{ "interproscan-version": "5.45-80.0", "results": [ { "sequence" : "MIEWLQTEVFPAAVESGSFGAGAKFLGYEPSGQQDSDISDIFFGTVNVELPDGGQLSERVYVKVQTKETKFYHLSHNIDAHFHNEVLFYTELLPLLRKYDTENFLAGSIPEFVYGRATLGAAPDQDVIVQKDLSLKGFRMTKEKLFLDEKHIRLTVDRLAKFHALAIMCQHENPEAFNEVVSKIKATNLHGPSDGPKQKDPFDQIKFRGIDPLKEDPEYSERLTEISRHCEWGASWLKKYMGPSDAINTLTHGDLTRHNLMFRYDDQGEPVEVVLCDWACIRYCTPVSDLSLFLILDTSPELKRSHWDIFLSEYYSALSRVLDGHASKPSFEDLQLEMRKKGVYGYHWAVYMLPAGFETELNHKMENTPLTELFQLLSEAGGPKATEYLTDIVKFMLDHEFIFEVDE", "md5" : "d9c3ec4f1b3c0df9af58a8a30a83aa73", "matches" : [ { "signature" : { "accession" : "PF02958", "name" : "EcKinase", "description" : "Ecdysteroid kinase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004119", "name" : "EcKL", "description" : "Ecdysteroid kinase-like", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Indole alkaloid biosynthesis", "databaseName" : "KEGG", "id" : "00901+2.7.1.222" }, { "name" : "Psilocybin biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-7936" } ] } }, "locations" : [ { "start" : 45, "end" : 322, "hmmStart" : 13, "hmmEnd" : 289, "hmmLength" : 294, "hmmBounds" : "INCOMPLETE", "evalue" : 6.2E-47, "score" : 160.3, "envelopeStart" : 34, "envelopeEnd" : 325, "postProcessed" : true, "location-fragments" : [ { "start" : 45, "end" : 322, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-47, "score" : 160.8, "model-ac" : "PF02958" }, { "signature" : { "accession" : "G3DSA:3.90.1200.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 174, "end" : 310, "hmmStart" : 82, "hmmEnd" : 152, "hmmLength" : 241, "hmmBounds" : "COMPLETE", "evalue" : 6.0E-6, "score" : 27.8, "envelopeStart" : 174, "envelopeEnd" : 310, "postProcessed" : true, "location-fragments" : [ { "start" : 174, "end" : 310, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-6, "score" : 28.7, "model-ac" : "3atsA02" }, { "signature" : { "accession" : "SM00587", "name" : "121neu2hmm", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR015897", "name" : "CHK_kinase-like", "description" : "CHK kinase-like", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 128, "end" : 324, "hmmStart" : 1, "hmmEnd" : 203, "hmmLength" : 203, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-29, "score" : 114.4, "location-fragments" : [ { "start" : 128, "end" : 324, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-29, "score" : 114.4, "model-ac" : "SM00587" }, { "signature" : { "accession" : "PTHR11012", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 31, "end" : 357, "hmmStart" : 43, "hmmEnd" : 362, "hmmLength" : 414, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 403, "location-fragments" : [ { "start" : 31, "end" : 357, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-53, "familyName" : "UNCHARACTERIZED", "score" : 185.5, "model-ac" : "PTHR11012" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 48, "end" : 339, "hmmLength" : 392, "location-fragments" : [ { "start" : 48, "end" : 339, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.67E-17, "model-ac" : "0054547" } ], "xref" : [ { "name" : "XP_018909697.1 PREDICTED: uncharacterized protein LOC109038891 [Bemisia tabaci]", "id" : "XP_018909697.1" }, { "name" : "XP_018909696.1 PREDICTED: uncharacterized protein LOC109038891 [Bemisia tabaci]", "id" : "XP_018909696.1" } ] },{ "sequence" : "MDSLIFADRIMYARSQQRNFTKMPVTGGTPVTQEVAIAFRSIVFGTSVAPPRGEWLRTGFVFRDADKELAYGLKAPRNGCRGLLSVVQAYILKQLLFERKDFKKNEPVMQPEMLLRPSRGKQLEALWLAISDILWRIGEKTKAVVCLPQDQPYVSHSLNYFQDSVTEKLHIFEIANLEELQIFIKRYIHLFLEEPGPGALLLLYSAVATRGTKNVISDIMDEKGYLVTGAEEGSQSIIMLLLTGRATPYLHNGVVYVGDEEHYAIPQFGVLQRSEIGFLLFDEGVEEKAPGSRLKTPSLPIWVVCCLGHFGVIFNTNRELLRNYHAERRFELIYYTCGGSQCQLTVDTRHDGSSTQVSTSEDTASSSLANLEKLIHTKWQDAHIHWNGTSNFI", "md5" : "bb7f2f9fc1207b05d7d1804696907133", "matches" : [ { "signature" : { "accession" : "PTHR12473:SF4", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 390, "hmmStart" : 186, "hmmEnd" : 549, "hmmLength" : 552, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 393, "location-fragments" : [ { "start" : 16, "end" : 390, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-104, "familyName" : "", "score" : 353.1, "model-ac" : "PTHR12473:SF4" }, { "signature" : { "accession" : "PTHR12473", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR039785", "name" : "MINY3/4", "description" : "Deubiquitinating enzyme MINDY-3/4", "type" : "FAMILY", "goXRefs" : [ { "name" : "Lys48-specific deubiquitinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:1990380" }, { "name" : "protein K48-linked deubiquitination", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0071108" }, { "name" : "thiol-dependent ubiquitin-specific protease activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004843" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 16, "end" : 390, "hmmStart" : 186, "hmmEnd" : 549, "hmmLength" : 552, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 393, "location-fragments" : [ { "start" : 16, "end" : 390, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-104, "familyName" : "", "score" : 353.1, "model-ac" : "PTHR12473" }, { "signature" : { "accession" : "SM01174", "name" : "DUF4205_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR025257", "name" : "MINDY-3/4_CD", "description" : "Deubiquitinating enzyme MINDY-3/4, conserved domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 40, "end" : 388, "hmmStart" : 1, "hmmEnd" : 438, "hmmLength" : 438, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-131, "score" : 452.1, "location-fragments" : [ { "start" : 40, "end" : 388, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-131, "score" : 452.1, "model-ac" : "SM01174" }, { "signature" : { "accession" : "PF13898", "name" : "DUF4205", "description" : "Domain of unknown function (DUF4205)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR025257", "name" : "MINDY-3/4_CD", "description" : "Deubiquitinating enzyme MINDY-3/4, conserved domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 40, "end" : 388, "hmmStart" : 1, "hmmEnd" : 351, "hmmLength" : 351, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-129, "score" : 432.3, "envelopeStart" : 40, "envelopeEnd" : 388, "postProcessed" : true, "location-fragments" : [ { "start" : 40, "end" : 388, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-129, "score" : 432.5, "model-ac" : "PF13898" } ], "xref" : [ { "name" : "XP_018910120.1 PREDICTED: protein FAM188B2 isoform X4 [Bemisia tabaci]", "id" : "XP_018910120.1" } ] },{ "sequence" : "MGDGKSNDIFPTLNSFCFCISLRTGSLCIAWYYLIAGLMGIIPMLPKQYDFITSISTTGNTGEMITRLLIVEYYFLLLLMVISCIFLIDGIRKKIPKEVRPFIFYGCIFFIHEIFVILLLLFTPLRHDAETFLTPISTVVATALTNPWLKAFDLVLAAYLLLTVHSYYKELKREVGQNNSGAIV", "md5" : "4d93fdf78cb0af8c1456b9e1f85b7315", "matches" : [ { "signature" : { "accession" : "PTHR34609", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 177, "hmmStart" : 5, "hmmEnd" : 159, "hmmLength" : 172, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 10, "envelopeEnd" : 181, "location-fragments" : [ { "start" : 12, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.2E-12, "familyName" : "FAMILY NOT NAMED", "score" : 48.3, "model-ac" : "PTHR34609" } ], "xref" : [ { "name" : "XP_018909746.1 PREDICTED: uncharacterized protein LOC109038929 isoform X1 [Bemisia tabaci]", "id" : "XP_018909746.1" } ] },{ "sequence" : "MDWFFAVTLLACLQSCITLPRRNLEGHFIGEGSNDLATSILKGYEHDTSNFVFSPLGYSTILAILAEGAVGKTREEIISTLKFPVDNTVVRETFKTVLQRMTDKETLNKPEFKTYFYIYKNISVHDEYRKVLLENYLTEVKSVERPEEEGTIEISYESSTETSEGSSGDEDLLAEDKRHSTTLYPLLPQETTTEKEQAQQEKLHSRSEVVHPQPEKESEKIIKKQVQPEDEIKEKVDAARRAENERILRLAKKFLGINLRQKRFSQPQELMGISANQLGSKNGNDIQSKMIVFNGLYFKGSFVTPFQTTKNQTDGVFYTSEKEKLPAEMMNALGNFQYGELTDLDAKAIELPYEGGRYSLLILLPRTRGGLSKLVADLSGYSLRNLHKQMSVQPVSVRLPKFDFRAISKPVSILKKSGISSIFSTDADLSRLSPDEGLFLNELVQLVTIKVDEDSSSTNLLTASALSLRSIYSVKFYADHPFLFFLRDHQENIIISAGKIANPSERYKN", "md5" : "cb8c674cbce368611dc377fe7628102e", "matches" : [ { "signature" : { "accession" : "PTHR11461:SF292", "name" : "SERPIN 100A", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 282, "end" : 501, "hmmStart" : 392, "hmmEnd" : 629, "hmmLength" : 649, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 272, "envelopeEnd" : 508, "location-fragments" : [ { "start" : 282, "end" : 501, "dc-status" : "CONTINUOUS" } ] }, { "start" : 7, "end" : 169, "hmmStart" : 11, "hmmEnd" : 174, "hmmLength" : 649, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 260, "location-fragments" : [ { "start" : 7, "end" : 169, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-76, "familyName" : "SERPIN 100A", "score" : 260.7, "model-ac" : "PTHR11461:SF292" }, { "signature" : { "accession" : "G3DSA:3.30.497.10", "name" : "Antithrombin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042178", "name" : "Serpin_sf_1", "description" : "Serpin superfamily, domain 1", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 20, "end" : 163, "hmmStart" : 26, "hmmEnd" : 140, "hmmLength" : 241, "hmmBounds" : "COMPLETE", "evalue" : 3.6E-19, "score" : 71.1, "envelopeStart" : 20, "envelopeEnd" : 163, "postProcessed" : true, "location-fragments" : [ { "start" : 20, "end" : 163, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-30, "score" : 106.9, "model-ac" : "2peeA01" }, { "signature" : { "accession" : "SSF56574", "name" : "Serpins", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036186", "name" : "Serpin_sf", "description" : "Serpin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 503, "hmmLength" : 378, "location-fragments" : [ { "start" : 264, "end" : 503, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 32, "end" : 144, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.6E-71, "model-ac" : "0051067" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 195, "end" : 216, "location-fragments" : [ { "start" : 195, "end" : 216, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR11461", "name" : "SERINE PROTEASE INHIBITOR, SERPIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR000215", "name" : "Serpin_fam", "description" : "Serpin family", "type" : "FAMILY", "goXRefs" : [ { "name" : "extracellular space", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005615" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 169, "hmmStart" : 11, "hmmEnd" : 174, "hmmLength" : 649, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 260, "location-fragments" : [ { "start" : 7, "end" : 169, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-76, "familyName" : "SERPIN 100A", "score" : 260.7, "model-ac" : "PTHR11461" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 148, "end" : 216, "location-fragments" : [ { "start" : 148, "end" : 216, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS00284", "name" : "SERPIN", "description" : "Serpins signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR023795", "name" : "Serpin_CS", "description" : "Serpin, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 476, "end" : 486, "level" : "STRONG", "cigarAlignment" : "9M1I1M", "alignment" : "FYADHPFLFfL", "location-fragments" : [ { "start" : 476, "end" : 486, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00284" }, { "signature" : { "accession" : "G3DSA:3.30.497.10", "name" : "Antithrombin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042178", "name" : "Serpin_sf_1", "description" : "Serpin superfamily, domain 1", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 399, "end" : 465, "hmmStart" : 188, "hmmEnd" : 235, "hmmLength" : 248, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.1E-6, "score" : 27.4, "envelopeStart" : 395, "envelopeEnd" : 465, "postProcessed" : true, "location-fragments" : [ { "start" : 399, "end" : 465, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-26, "score" : 95.3, "model-ac" : "3nddA01" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 153, "end" : 167, "location-fragments" : [ { "start" : 153, "end" : 167, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00172", "name" : "SERPIN", "description" : "SERPIN", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 32, "end" : 500, "sites" : [ ], "evalue" : 2.091E-68, "score" : 221.743, "location-fragments" : [ { "start" : 32, "end" : 500, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00172" }, { "signature" : { "accession" : "PTHR11461", "name" : "SERINE PROTEASE INHIBITOR, SERPIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR000215", "name" : "Serpin_fam", "description" : "Serpin family", "type" : "FAMILY", "goXRefs" : [ { "name" : "extracellular space", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005615" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 282, "end" : 501, "hmmStart" : 392, "hmmEnd" : 629, "hmmLength" : 649, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 272, "envelopeEnd" : 508, "location-fragments" : [ { "start" : 282, "end" : 501, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-76, "familyName" : "SERPIN 100A", "score" : 260.7, "model-ac" : "PTHR11461" }, { "signature" : { "accession" : "PF00079", "name" : "Serpin", "description" : "Serpin (serine protease inhibitor)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR023796", "name" : "Serpin_dom", "description" : "Serpin domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 285, "end" : 503, "hmmStart" : 150, "hmmEnd" : 371, "hmmLength" : 371, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.7E-49, "score" : 167.6, "envelopeStart" : 274, "envelopeEnd" : 503, "postProcessed" : true, "location-fragments" : [ { "start" : 285, "end" : 503, "dc-status" : "CONTINUOUS" } ] }, { "start" : 33, "end" : 144, "hmmStart" : 3, "hmmEnd" : 118, "hmmLength" : 371, "hmmBounds" : "INCOMPLETE", "evalue" : 9.3E-14, "score" : 51.5, "envelopeStart" : 31, "envelopeEnd" : 163, "postProcessed" : true, "location-fragments" : [ { "start" : 33, "end" : 144, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-65, "score" : 221.4, "model-ac" : "PF00079" }, { "signature" : { "accession" : "SM00093", "name" : "serpin2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR023796", "name" : "Serpin_dom", "description" : "Serpin domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 38, "end" : 503, "hmmStart" : 1, "hmmEnd" : 372, "hmmLength" : 372, "hmmBounds" : "COMPLETE", "evalue" : 1.0E-22, "score" : 91.5, "location-fragments" : [ { "start" : 38, "end" : 503, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-22, "score" : 91.5, "model-ac" : "SM00093" } ], "xref" : [ { "name" : "XP_018909869.1 PREDICTED: serpin B5-like [Bemisia tabaci]", "id" : "XP_018909869.1" } ] },{ "sequence" : "MKRFTVLPVTLFRIQHKLPVELRDHATQMAKQRTSFDLKTYTEKKLVRPMEGDKFHTPNGLSLRPKGQTMAQILTEFRGSPTIFCIQAGTPLPERCVLLHEHTDHYSLQVAEEMPLDEFNTILNEYLKKHPIITKKAWLEAWNDPDDQDN", "md5" : "54486b124a50d10955021baa9bc3a042", "matches" : [ ], "xref" : [ { "name" : "XP_018910531.1 PREDICTED: uncharacterized protein LOC109039495 [Bemisia tabaci]", "id" : "XP_018910531.1" } ] },{ "sequence" : "MLWCLRVSVGAFLFCSCFEQRPCATIGDAFYSLDPLLELYTPLNTENTRCSDQTIYFRNAAKKRTPWALQMLDASSKVPSSLLAGNFIDLGNFDQCLAVRSDASDAHLHVVGKYCLIKAIFNRTWNENQEVSLRDLSEAWTWSVCIPAACSGEDLTHHLKLSLNGIAKQVHEVHCTSGTDNAGLSATSLLMM", "md5" : "876a323788930cdf751f8cdcb12104f3", "matches" : [ { "signature" : { "accession" : "SM00703", "name" : "nrf", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006621", "name" : "Nose-resist-to-fluoxetine_N", "description" : "Nose resistant-to-fluoxetine protein, N-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 47, "end" : 177, "hmmStart" : 1, "hmmEnd" : 178, "hmmLength" : 178, "hmmBounds" : "COMPLETE", "evalue" : 2.6E-14, "score" : 63.6, "location-fragments" : [ { "start" : 47, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-14, "score" : 63.6, "model-ac" : "SM00703" }, { "signature" : { "accession" : "PTHR11161", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 36, "end" : 133, "hmmStart" : 140, "hmmEnd" : 240, "hmmLength" : 788, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 11, "envelopeEnd" : 141, "location-fragments" : [ { "start" : 36, "end" : 133, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-20, "familyName" : "DROP DEAD", "score" : 74.4, "model-ac" : "PTHR11161" }, { "signature" : { "accession" : "PTHR11161:SF4", "name" : "DROP DEAD", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 36, "end" : 133, "hmmStart" : 140, "hmmEnd" : 240, "hmmLength" : 788, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 11, "envelopeEnd" : 141, "location-fragments" : [ { "start" : 36, "end" : 133, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-20, "familyName" : "DROP DEAD", "score" : 74.4, "model-ac" : "PTHR11161:SF4" }, { "signature" : { "accession" : "PS51257", "name" : "PROKAR_LIPOPROTEIN", "description" : "Prokaryotic membrane lipoprotein lipid attachment site profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 17, "score" : 5.0, "alignment" : "MLWC-LR-----------------VSVGAFLFCSC", "location-fragments" : [ { "start" : 1, "end" : 17, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51257" } ], "xref" : [ { "name" : "XP_018910283.1 PREDICTED: uncharacterized protein LOC109039313 [Bemisia tabaci]", "id" : "XP_018910283.1" } ] },{ "sequence" : "MRGIMKPEVKPSDTQSVISDAGTSISGCGSSLSDNREDLQEFAFRLGLPSVDHLTRDRFRVDRRKLESMILGEEHLEPADVFFQNIMESTETRIVWPVKLKIGAKSKKDPCIRIAGRTEDVAEAKKKILAILETRPWVINFSSGYKGYRVTMKLDVSYTDHSHIIGKGGQTIKSVMEKTGCHIHFPDSNRINQTEKSNQISIAGEMTGVERARARVRELTPLIFSFELPLLGGIQPCPEQNCEEIKEVEGLYNVQVMFRTRPKLHSTLVVVKGCEWELASVKEATIVLMNKLCDSLANQMPVHMSMEISPIHHSVVLGRNNTNLKTIMHHTGVQVMFPDANDPNIPSLKKSSVTITGGINQVYLARQMLLGSLPMVIMFDITGDTAMMSNEQINELMHTLDVVISVRYKPKQSVTSVSIRGVERNASNVYEARRILLKLNEPSIKAVIPDSYNIPSPTPSYLFNAGLSTSPGAGLSNLLDNRFSKNNNISPINYNILNSRKVFPSELSQLPSSMWPLMPNLAPQFFSPNQRMHHQEQLTATLQNHQDILSQSSLSLPDIKDCQGAYSSLSSNTSSLSSPTASPRNVSPIPCAPENKLDLSSLLTNLTDENGFERPLSMDYNAAKMKAFRTVQNQNFSAGRLRIPTTSWCGLGFSQSSPTHKLKEQLMNDNLPVTQLEDANSSSPAASVCSDNDLNFAVSSYLDSAPGATLDSVFAAQERDITSLFISLGFEKYIPLFKSQEIDLYTFMTLSDCDLKEIGVNALGARRKLLLTIAELKKRKNSGLAFNGSAAPGAERKGSRSSLVDW", "md5" : "39ce5f44b25afe9858233b78b086aa3c", "matches" : [ { "signature" : { "accession" : "G3DSA:3.30.310.270", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 144, "end" : 266, "hmmStart" : 27, "hmmEnd" : 127, "hmmLength" : 216, "hmmBounds" : "COMPLETE", "evalue" : 3.7E-22, "score" : 80.5, "envelopeStart" : 144, "envelopeEnd" : 266, "postProcessed" : true, "location-fragments" : [ { "start" : 144, "end" : 266, "dc-status" : "CONTINUOUS" } ] }, { "start" : 278, "end" : 456, "hmmStart" : 25, "hmmEnd" : 198, "hmmLength" : 216, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-24, "score" : 86.9, "envelopeStart" : 278, "envelopeEnd" : 456, "postProcessed" : true, "location-fragments" : [ { "start" : 278, "end" : 456, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-54, "score" : 184.3, "model-ac" : "3n89A01" }, { "signature" : { "accession" : "PF00013", "name" : "KH_1", "description" : "KH domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004088", "name" : "KH_dom_type_1", "description" : "K Homology domain, type 1", "type" : "DOMAIN", "goXRefs" : [ { "name" : "RNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003723" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 153, "end" : 218, "hmmStart" : 3, "hmmEnd" : 66, "hmmLength" : 66, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.0E-14, "score" : 52.2, "envelopeStart" : 149, "envelopeEnd" : 218, "postProcessed" : true, "location-fragments" : [ { "start" : 153, "end" : 218, "dc-status" : "CONTINUOUS" } ] }, { "start" : 306, "end" : 370, "hmmStart" : 4, "hmmEnd" : 65, "hmmLength" : 66, "hmmBounds" : "INCOMPLETE", "evalue" : 4.8E-8, "score" : 32.7, "envelopeStart" : 303, "envelopeEnd" : 371, "postProcessed" : true, "location-fragments" : [ { "start" : 306, "end" : 370, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-29, "score" : 101.7, "model-ac" : "PF00013" }, { "signature" : { "accession" : "PTHR10627:SF39", "name" : "PROTEIN BICAUDAL C HOMOLOG 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 616, "end" : 782, "hmmStart" : 553, "hmmEnd" : 745, "hmmLength" : 753, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 569, "envelopeEnd" : 791, "location-fragments" : [ { "start" : 616, "end" : 782, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-159, "familyName" : "PROTEIN BICAUDAL C HOMOLOG 1", "score" : 534.7, "model-ac" : "PTHR10627:SF39" }, { "signature" : { "accession" : "cd02394", "name" : "vigilin_like_KH", "description" : "vigilin_like_KH", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 151, "end" : 217, "sites" : [ { "description" : "G-X-X-G motif", "numLocations" : 4, "siteLocations" : [ { "start" : 167, "end" : 167, "residue" : "K" }, { "start" : 169, "end" : 169, "residue" : "G" }, { "start" : 168, "end" : 168, "residue" : "G" }, { "start" : 166, "end" : 166, "residue" : "G" } ] }, { "description" : "putative nucleic acid binding region", "numLocations" : 17, "siteLocations" : [ { "start" : 185, "end" : 185, "residue" : "F" }, { "start" : 177, "end" : 177, "residue" : "E" }, { "start" : 183, "end" : 183, "residue" : "I" }, { "start" : 167, "end" : 167, "residue" : "K" }, { "start" : 172, "end" : 172, "residue" : "I" }, { "start" : 173, "end" : 173, "residue" : "K" }, { "start" : 184, "end" : 184, "residue" : "H" }, { "start" : 159, "end" : 159, "residue" : "T" }, { "start" : 162, "end" : 162, "residue" : "S" }, { "start" : 166, "end" : 166, "residue" : "G" }, { "start" : 163, "end" : 163, "residue" : "H" }, { "start" : 161, "end" : 161, "residue" : "H" }, { "start" : 169, "end" : 169, "residue" : "G" }, { "start" : 165, "end" : 165, "residue" : "I" }, { "start" : 176, "end" : 176, "residue" : "M" }, { "start" : 168, "end" : 168, "residue" : "G" }, { "start" : 182, "end" : 182, "residue" : "H" } ] } ], "evalue" : 1.78132E-17, "score" : 74.8557, "location-fragments" : [ { "start" : 151, "end" : 217, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd02394" }, { "signature" : { "accession" : "G3DSA:1.10.150.50", "name" : "Transcription Factor", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013761", "name" : "SAM/pointed_sf", "description" : "Sterile alpha motif/pointed domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 719, "end" : 787, "hmmStart" : 5, "hmmEnd" : 64, "hmmLength" : 74, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-17, "score" : 64.2, "envelopeStart" : 719, "envelopeEnd" : 787, "postProcessed" : true, "location-fragments" : [ { "start" : 719, "end" : 787, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-18, "score" : 65.8, "model-ac" : "3k1rB00" }, { "signature" : { "accession" : "PS50084", "name" : "KH_TYPE_1", "description" : "Type-1 KH domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 301, "end" : 369, "score" : 11.28, "alignment" : "PVHMSMEISPIHHSVVLGRNNTNLKTIMHHTGVQVMFPDANDPniPSLKKSSVTITGGINQVYLARQML", "location-fragments" : [ { "start" : 301, "end" : 369, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50084" }, { "signature" : { "accession" : "PTHR10627:SF39", "name" : "PROTEIN BICAUDAL C HOMOLOG 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 146, "end" : 568, "hmmStart" : 9, "hmmEnd" : 413, "hmmLength" : 753, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 144, "envelopeEnd" : 613, "location-fragments" : [ { "start" : 146, "end" : 568, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-159, "familyName" : "PROTEIN BICAUDAL C HOMOLOG 1", "score" : 534.7, "model-ac" : "PTHR10627:SF39" }, { "signature" : { "accession" : "PS50084", "name" : "KH_TYPE_1", "description" : "Type-1 KH domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 149, "end" : 216, "score" : 16.164, "alignment" : "RVTMKLDVSYTDHSHIIGKGGQTIKSVMEKTGCHIHFPDSNRInQTEKSNQISIAGEMTGVERARARV", "location-fragments" : [ { "start" : 149, "end" : 216, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50084" }, { "signature" : { "accession" : "SSF47769", "name" : "SAM/Pointed domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR013761", "name" : "SAM/pointed_sf", "description" : "Sterile alpha motif/pointed domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 718, "end" : 781, "hmmLength" : 78, "location-fragments" : [ { "start" : 718, "end" : 781, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.83E-12, "model-ac" : "0050795" }, { "signature" : { "accession" : "PF00536", "name" : "SAM_1", "description" : "SAM domain (Sterile alpha motif)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001660", "name" : "SAM", "description" : "Sterile alpha motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 727, "end" : 777, "hmmStart" : 14, "hmmEnd" : 64, "hmmLength" : 64, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.1E-9, "score" : 36.0, "envelopeStart" : 717, "envelopeEnd" : 777, "postProcessed" : true, "location-fragments" : [ { "start" : 727, "end" : 777, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-9, "score" : 37.0, "model-ac" : "PF00536" }, { "signature" : { "accession" : "SM00454", "name" : "SAM_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001660", "name" : "SAM", "description" : "Sterile alpha motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 713, "end" : 779, "hmmStart" : 1, "hmmEnd" : 67, "hmmLength" : 67, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-8, "score" : 43.7, "location-fragments" : [ { "start" : 713, "end" : 779, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-8, "score" : 43.7, "model-ac" : "SM00454" }, { "signature" : { "accession" : "PTHR10627", "name" : "SCP160", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 146, "end" : 568, "hmmStart" : 9, "hmmEnd" : 413, "hmmLength" : 753, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 144, "envelopeEnd" : 613, "location-fragments" : [ { "start" : 146, "end" : 568, "dc-status" : "CONTINUOUS" } ] }, { "start" : 616, "end" : 782, "hmmStart" : 553, "hmmEnd" : 745, "hmmLength" : 753, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 569, "envelopeEnd" : 791, "location-fragments" : [ { "start" : 616, "end" : 782, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-159, "familyName" : "PROTEIN BICAUDAL C HOMOLOG 1", "score" : 534.7, "model-ac" : "PTHR10627" }, { "signature" : { "accession" : "SSF54791", "name" : "Eukaryotic type KH-domain (KH-domain type I)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036612", "name" : "KH_dom_type_1_sf", "description" : "K Homology domain, type 1 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "RNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003723" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 301, "end" : 371, "hmmLength" : 84, "location-fragments" : [ { "start" : 301, "end" : 371, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.41E-12, "model-ac" : "0052299" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 21, "location-fragments" : [ { "start" : 1, "end" : 21, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd02394", "name" : "vigilin_like_KH", "description" : "vigilin_like_KH", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 304, "end" : 370, "sites" : [ { "description" : "putative nucleic acid binding region", "numLocations" : 17, "siteLocations" : [ { "start" : 311, "end" : 311, "residue" : "I" }, { "start" : 313, "end" : 313, "residue" : "H" }, { "start" : 329, "end" : 329, "residue" : "H" }, { "start" : 328, "end" : 328, "residue" : "M" }, { "start" : 334, "end" : 334, "residue" : "Q" }, { "start" : 320, "end" : 320, "residue" : "N" }, { "start" : 319, "end" : 319, "residue" : "R" }, { "start" : 315, "end" : 315, "residue" : "V" }, { "start" : 324, "end" : 324, "residue" : "L" }, { "start" : 337, "end" : 337, "residue" : "F" }, { "start" : 336, "end" : 336, "residue" : "M" }, { "start" : 317, "end" : 317, "residue" : "L" }, { "start" : 325, "end" : 325, "residue" : "K" }, { "start" : 335, "end" : 335, "residue" : "V" }, { "start" : 314, "end" : 314, "residue" : "S" }, { "start" : 321, "end" : 321, "residue" : "N" }, { "start" : 318, "end" : 318, "residue" : "G" } ] }, { "description" : "G-X-X-G motif", "numLocations" : 4, "siteLocations" : [ { "start" : 320, "end" : 320, "residue" : "N" }, { "start" : 319, "end" : 319, "residue" : "R" }, { "start" : 321, "end" : 321, "residue" : "N" }, { "start" : 318, "end" : 318, "residue" : "G" } ] } ], "evalue" : 1.65139E-10, "score" : 55.2105, "location-fragments" : [ { "start" : 304, "end" : 370, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd02394" }, { "signature" : { "accession" : "SM00322", "name" : "kh_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR004087", "name" : "KH_dom", "description" : "K Homology domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 148, "end" : 221, "hmmStart" : 1, "hmmEnd" : 63, "hmmLength" : 63, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-14, "score" : 64.9, "location-fragments" : [ { "start" : 148, "end" : 221, "dc-status" : "CONTINUOUS" } ] }, { "start" : 53, "end" : 133, "hmmStart" : 1, "hmmEnd" : 63, "hmmLength" : 63, "hmmBounds" : "COMPLETE", "evalue" : 61.0, "score" : 0.2, "location-fragments" : [ { "start" : 53, "end" : 133, "dc-status" : "CONTINUOUS" } ] }, { "start" : 300, "end" : 374, "hmmStart" : 1, "hmmEnd" : 63, "hmmLength" : 63, "hmmBounds" : "COMPLETE", "evalue" : 1.0E-5, "score" : 35.0, "location-fragments" : [ { "start" : 300, "end" : 374, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-25, "score" : 100.1, "model-ac" : "SM00322" }, { "signature" : { "accession" : "SSF54791", "name" : "Eukaryotic type KH-domain (KH-domain type I)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036612", "name" : "KH_dom_type_1_sf", "description" : "K Homology domain, type 1 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "RNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003723" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 147, "end" : 219, "hmmLength" : 91, "location-fragments" : [ { "start" : 147, "end" : 219, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.24E-15, "model-ac" : "0052298" }, { "signature" : { "accession" : "PS50105", "name" : "SAM_DOMAIN", "description" : "SAM domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001660", "name" : "SAM", "description" : "Sterile alpha motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 716, "end" : 779, "score" : 12.1, "alignment" : "AQERDITSLFISLGFEKYIPLFKSQEIDLYTFMTLSDCDLKEIGVNALGARRKLLLTIAELKKR", "location-fragments" : [ { "start" : 716, "end" : 779, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50105" } ], "xref" : [ { "name" : "XP_018909986.1 PREDICTED: protein bicaudal C [Bemisia tabaci]", "id" : "XP_018909986.1" } ] },{ "sequence" : "MDEAKKRERDRDRKRKYREKLVLNNPDKVLQTKLKNKKYYQARSSKGLLKTVNKMSDEEKFAKRQMWKNQKQRQRLRKSQEVHKIPVVNDDSGLNESNSEFESLGADPLYSAVDVCAIVGPSEIVSCSAPPPPSLNSSPNTTCRSIGPTPVFQNSVRESIALSATTSCPSNLVNSKTPSRQLILGKKIARRNRDKLLGRIKILEQQVHFYKRLSQKYKKRWQRAVRKRVSQNQSNQSSQTDSPQKVVRQIISSGKEEVKRQLLFGQALEKQLRKNSRECKNLVQKRNFAKSIGGRVCKKYGMEKELQRRKISTYYLRKKYGGKVMSIGSRLKRSSKFVKLKSTVMHFFEDDEVSVMTPGKKQYITRRKVQKQRRFLRDSLKNLHK", "md5" : "498ea1cf4ff3a54e020c0fbb0adf1038", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 227, "end" : 245, "location-fragments" : [ { "start" : 227, "end" : 245, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 20, "location-fragments" : [ { "start" : 1, "end" : 20, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 265, "end" : 285, "location-fragments" : [ { "start" : 265, "end" : 285, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 186, "end" : 220, "location-fragments" : [ { "start" : 186, "end" : 220, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 225, "end" : 245, "location-fragments" : [ { "start" : 225, "end" : 245, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910017.1 PREDICTED: uncharacterized protein LOC109039118, partial [Bemisia tabaci]", "id" : "XP_018910017.1" } ] },{ "sequence" : "MALSRKEFIEKYKEDRPAAAHFAECISRAYMTGVAFFGIGAVSFHLAQLAFKERLPYSPQIRLALTLFFGTGVAYQVGAKGMKECQAAFMEEEGRKSPPTSGALEDLSDL", "md5" : "b6ed3262b5092ae27af74c89d79eb6bd", "matches" : [ { "signature" : { "accession" : "G3DSA:1.10.3350.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR038259", "name" : "Tmem141_sf", "description" : "Tmem141 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 105, "hmmStart" : 10, "hmmEnd" : 100, "hmmLength" : 108, "hmmBounds" : "COMPLETE", "evalue" : 2.2E-15, "score" : 58.8, "envelopeStart" : 1, "envelopeEnd" : 105, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-15, "score" : 59.0, "model-ac" : "2lorA00" }, { "signature" : { "accession" : "PTHR47229", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR026788", "name" : "Tmem141", "description" : "Transmembrane protein 141", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 100, "hmmStart" : 14, "hmmEnd" : 101, "hmmLength" : 129, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 108, "location-fragments" : [ { "start" : 13, "end" : 100, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-13, "familyName" : "FAMILY NOT NAMED", "score" : 54.0, "model-ac" : "PTHR47229" }, { "signature" : { "accession" : "PF15110", "name" : "TMEM141", "description" : "TMEM141 protein family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR026788", "name" : "Tmem141", "description" : "Transmembrane protein 141", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 93, "hmmStart" : 6, "hmmEnd" : 89, "hmmLength" : 91, "hmmBounds" : "INCOMPLETE", "evalue" : 4.2E-16, "score" : 59.3, "envelopeStart" : 6, "envelopeEnd" : 95, "postProcessed" : true, "location-fragments" : [ { "start" : 10, "end" : 93, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-16, "score" : 59.5, "model-ac" : "PF15110" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 91, "end" : 110, "location-fragments" : [ { "start" : 91, "end" : 110, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909578.1 PREDICTED: uncharacterized protein LOC109038827 [Bemisia tabaci]", "id" : "XP_018909578.1" } ] },{ "sequence" : "MPEYPNQESAEGGRSVRLTNDDFRKLLMTPRSSAPSSFPTSSVVNQFKEAQAEEPKKFPEDVAQEDDKAERRRKKKSFYAKLKKQEEDKMAELAEKYRDRAKERREGANPDYQAEDPLASASGYRAVAPDLKSGMDAAERRRQMIQESKFLGGDMEHTHLVKGLDYALLQKVRSEIEMKEQEQEQEMEQIISKPRKEKKVEEEEMQFKTRLGRNVYRTIMGTKEIKRNDLFAPQRMAYVIDIQDEIADTDIPMTLIRSKADIPNLEEKPTLTTNDIVINKLAQILSYLRQGPRHSKKSKKKEKSQVEENIYPEVGDYNPSLVKSESSGKRKTSNYFSSTDRENELQQQSLDRQEERKKILRGVAAKEEGGKQSGLLSRLAAEPTGYAECYPGLEEMQDAIDDSDDEVDFTKMDLGNKKGPVGRWDFDTTEEYSNYMNSKEALPKAAFQYGVKMADGRRTRKYNKEKNDRAELDREWNKIQNIIQKHKPDSSSKDSDGPAFKIPRYA", "md5" : "854d4ba9b761a195ccf6f5f6f84f1ce5", "matches" : [ { "signature" : { "accession" : "PF07808", "name" : "RED_N", "description" : "RED-like protein N-terminal region", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR012916", "name" : "RED_N", "description" : "RED-like, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 74, "end" : 301, "hmmStart" : 1, "hmmEnd" : 234, "hmmLength" : 235, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.2E-100, "score" : 335.9, "envelopeStart" : 74, "envelopeEnd" : 302, "postProcessed" : true, "location-fragments" : [ { "start" : 74, "end" : 301, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-100, "score" : 335.9, "model-ac" : "PF07808" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 345, "end" : 365, "location-fragments" : [ { "start" : 345, "end" : 365, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF07807", "name" : "RED_C", "description" : "RED-like protein C-terminal region", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR012492", "name" : "RED_C", "description" : "Protein RED, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 386, "end" : 494, "hmmStart" : 1, "hmmEnd" : 108, "hmmLength" : 112, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.4E-52, "score" : 176.2, "envelopeStart" : 386, "envelopeEnd" : 497, "postProcessed" : true, "location-fragments" : [ { "start" : 386, "end" : 494, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-52, "score" : 176.2, "model-ac" : "PF07807" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 292, "end" : 365, "location-fragments" : [ { "start" : 292, "end" : 365, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 320, "end" : 344, "location-fragments" : [ { "start" : 320, "end" : 344, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 464, "end" : 506, "location-fragments" : [ { "start" : 464, "end" : 506, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 80, "end" : 111, "location-fragments" : [ { "start" : 80, "end" : 111, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12765", "name" : "RED PROTEIN IK FACTOR CYTOKINE IK", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR039896", "name" : "Red-like", "description" : "Protein Red-like", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 19, "end" : 492, "hmmStart" : 2, "hmmEnd" : 500, "hmmLength" : 518, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 18, "envelopeEnd" : 501, "location-fragments" : [ { "start" : 19, "end" : 492, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-158, "familyName" : "RED PROTEIN IK FACTOR CYTOKINE IK", "score" : 531.7, "model-ac" : "PTHR12765" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 464, "end" : 494, "location-fragments" : [ { "start" : 464, "end" : 494, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 30, "end" : 48, "location-fragments" : [ { "start" : 30, "end" : 48, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 50, "end" : 73, "location-fragments" : [ { "start" : 50, "end" : 73, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 127, "location-fragments" : [ { "start" : 1, "end" : 127, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 169, "end" : 193, "location-fragments" : [ { "start" : 169, "end" : 193, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 83, "end" : 103, "location-fragments" : [ { "start" : 83, "end" : 103, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" } ], "xref" : [ { "name" : "XP_018910087.1 PREDICTED: protein Red [Bemisia tabaci]", "id" : "XP_018910087.1" } ] },{ "sequence" : "MRNLQTLFMFGLMVMGLCAVSWAQESAAAAAPPPPPGPPPPESPNSDPEQNSLDKDISVLPSFPTNGLSLLPEGVTPTAAVIGVVALAALLAASWPATGMRMCSLLGTCQDYNLPTVGTAYNNDAYSYSNPPPYTPTTYQKRSVSYVEPILRLLSSAYLQYGDTRAAKAVTSSGARRQRRRR", "md5" : "1cfaaa012c7121c3409bd3253fbc9997", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 29, "end" : 58, "location-fragments" : [ { "start" : 29, "end" : 58, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 29, "end" : 46, "location-fragments" : [ { "start" : 29, "end" : 46, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909722.1 PREDICTED: protein YABBY 3-like [Bemisia tabaci]", "id" : "XP_018909722.1" }, { "name" : "XP_018909721.1 PREDICTED: protein YABBY 3-like [Bemisia tabaci]", "id" : "XP_018909721.1" } ] },{ "sequence" : "MNRDKNNRSFMERSGDDDADDSDDASNTVRKKASACCVNTCSSDANINNHSENLELNVCSGETGTGNSSNNPHTAENKHYPTNKIIEVSKSSNNETCPVASCVFFPNLVDTPPPKKERIEAPTEENALLRRSHDAAHKKAESMEFFSSLVANLNLRRRNFPSQESRIGINYFPSELSERIENEIEDDTSDGDGVSMLSRPVRFSRSRTSLLSQKFAAIAPRPCSRLEIIFEKSQRLQNEEIVDNLLSSLDILLPSCKPEISEENDNSLKVIIDSNKKINDHTKWNPSQIKEDKKVDVSQCDSAVKQAPMYPGGGGNKMQGTYRFPTGDSNSGAGSQPNYSSNMNNSGPGFRGPRPGFSSLLSNVSSVDLSPFRGGAPIRFRLGTTPRMNPKKVQDKVPSAASQASSSPQSDSPTKEDEDVDLYSDIEHDPHEDVDEDKNFGTLEPPPEPPALLMGLGDEGTDEEEALVIDDKGADVYDPAEPCDDSNDASDSRNDEPVEAMNLTKPSSGYLHSPTYNDIVAQHDDKIGNGSSYDGVPKMMEPPPIPDALKIMEPPPFPSELLSKEIQGDDDEECPNFSLYSSASMNLVKKSSSVLDIPIPAQSNLDIPIPTQPNLDIPMPGPPNLDIPVPGSPTVANIPVPNSGSKTEKSTKEKKKKKKKKPLMYSVPTLEETILKERLGNYSSEDNTDSDDSEEKVKIIIPKRKKKASKKSKKKLAEAEKVDEMNDDAFENVNGEKKPEEKEEEEKENEEEKIVEVNVELDDNDEQSNFDDVSESKAPEKEGGDETEGDTQDEVESKIVSESSMDSIRPQVDEQTIDDNQETVSSLDNSDVSKLPDDKSDSSKMAILSNEGKEKLYDGEDESSIQGDILDIEAEANLQDATSIPDEQDDIKSSTPSKSNAQKSDGLVDITDEEMSEYDHSREEPSNKLDSLNTEAISEDEASIVDGNKESEQSCPTLPGLEGLQTDPISDSDGNAFDESNYSADKESEYDGGKRRKKKKKVQKEKEQSASENEDANVSKSKEKRNSADFEEGEIVDDKPKSSSKKDKKKKAKDKEAKENLDRSKSDHEKDKEKDKKQKKSKDGKSKDKDSVLQSSENKSSEENKEGSPSQSAADVNWKKLSKSTKDRNYRDGKGKPTNDKGRKSPERSTPKEREKKKEKRKELERYNVRKVLGEKVRLIGKDDFGRDLSLNRSMSRSRSRSRNRKGKGKSRSTSRSPYRSPVRSRAARSRSRSRSRSRSRRRLGRKRSRSKNRTLRRSYDRSRSKSRGRSRDRLRKKRASSRDRLRRSLSKGRVSRKKKKSVERRRNRSYSPEYSPARKRRSNSRYSFSPSWSSYSYSPSPGYSRSYSLSPSPSWSPENRALVYNREKNRPPKNITVIVPNEDANAKKKGKKRLSKKNKENEKRRKKRDRSPAPSKEVFTSGDNILVSVNFSNNKNDGTMGSLLHTNEYSTARRRSVEAEPPAKKSKETKNKEKKSKNSTPKKSRSARAVAVNEAAKNAKPIAVIDLNMSPFREETPSPKEVIVVTDSDLEAEQIEKEAPTSNRKVSRKSGSGRERDRDRDRDRDRDRDRNRDRDLGPPTSVSQPESPINDFMNTSAGGPKTPPEPRVAFSISSKQPQMRTMINPLMDGDEEEEQMEEANNEAEMNEIFSKGPNTPPEPPPDTNTPASPPTTPYDPFDPTKSRSPSPELGEQTSTPVNLRDGNKAHDTLSPNVLESNDLDSRNKTSPQVPDENKKTPDNLRSLQKDTIPILESPKQSSPNVSGVNDSNDGVVMKILGQAKIDLTTYKSPEPIAGTPRSTQLTPKPITPSKQSILSVSRAPAPASANKIPVYTPSITLNGEKMDEAPMDISGDSPYSPEPFEAEDLFEPPPISPPRTANKLPMPPIIRSSLTKANKSKFDALFGSLTRKTNTKQLKPVPYTPKPIIPSIKGTKAQKQMKGSKKEVGVKMDEDQLKILDDLPSSAVEMQVKDKYLKKLNRQERVVEEVKLVLKPHYAKKHIAKEDYKEILRRAVPKICHNRSGEINPQKIQMLIEAYVRKFQAKTSKKKGGAETTTNNTSNLSKRSKATRS", "md5" : "ed908bec61a135e97347fe5001b2dfee", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 613, "end" : 629, "location-fragments" : [ { "start" : 613, "end" : 629, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1226, "end" : 1255, "location-fragments" : [ { "start" : 1226, "end" : 1255, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1710, "end" : 1725, "location-fragments" : [ { "start" : 1710, "end" : 1725, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1004, "end" : 1104, "location-fragments" : [ { "start" : 1004, "end" : 1104, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1864, "end" : 1881, "location-fragments" : [ { "start" : 1864, "end" : 1881, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 817, "end" : 831, "location-fragments" : [ { "start" : 817, "end" : 831, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 378, "end" : 574, "location-fragments" : [ { "start" : 378, "end" : 574, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 770, "end" : 785, "location-fragments" : [ { "start" : 770, "end" : 785, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 396, "end" : 411, "location-fragments" : [ { "start" : 396, "end" : 411, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 740, "end" : 767, "location-fragments" : [ { "start" : 740, "end" : 767, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1838, "end" : 1889, "location-fragments" : [ { "start" : 1838, "end" : 1889, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 539, "end" : 553, "location-fragments" : [ { "start" : 539, "end" : 553, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 412, "end" : 442, "location-fragments" : [ { "start" : 412, "end" : 442, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1269, "end" : 1306, "location-fragments" : [ { "start" : 1269, "end" : 1306, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1391, "end" : 1405, "location-fragments" : [ { "start" : 1391, "end" : 1405, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1439, "end" : 1768, "location-fragments" : [ { "start" : 1439, "end" : 1768, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 26, "location-fragments" : [ { "start" : 1, "end" : 26, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2044, "end" : 2070, "location-fragments" : [ { "start" : 2044, "end" : 2070, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1726, "end" : 1742, "location-fragments" : [ { "start" : 1726, "end" : 1742, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1792, "end" : 1820, "location-fragments" : [ { "start" : 1792, "end" : 1820, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1120, "end" : 1190, "location-fragments" : [ { "start" : 1120, "end" : 1190, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1105, "end" : 1119, "location-fragments" : [ { "start" : 1105, "end" : 1119, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1686, "end" : 1702, "location-fragments" : [ { "start" : 1686, "end" : 1702, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1364, "end" : 1422, "location-fragments" : [ { "start" : 1364, "end" : 1422, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 678, "end" : 701, "location-fragments" : [ { "start" : 678, "end" : 701, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1452, "end" : 1476, "location-fragments" : [ { "start" : 1452, "end" : 1476, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1750, "end" : 1768, "location-fragments" : [ { "start" : 1750, "end" : 1768, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1627, "end" : 1647, "location-fragments" : [ { "start" : 1627, "end" : 1647, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1198, "end" : 1213, "location-fragments" : [ { "start" : 1198, "end" : 1213, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1654, "end" : 1677, "location-fragments" : [ { "start" : 1654, "end" : 1677, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 15, "location-fragments" : [ { "start" : 1, "end" : 15, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 980, "end" : 994, "location-fragments" : [ { "start" : 980, "end" : 994, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 713, "end" : 744, "location-fragments" : [ { "start" : 713, "end" : 744, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1527, "end" : 1577, "location-fragments" : [ { "start" : 1527, "end" : 1577, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1058, "end" : 1078, "location-fragments" : [ { "start" : 1058, "end" : 1078, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 609, "end" : 1323, "location-fragments" : [ { "start" : 609, "end" : 1323, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1578, "end" : 1598, "location-fragments" : [ { "start" : 1578, "end" : 1598, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 322, "end" : 348, "location-fragments" : [ { "start" : 322, "end" : 348, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 745, "end" : 769, "location-fragments" : [ { "start" : 745, "end" : 769, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1307, "end" : 1321, "location-fragments" : [ { "start" : 1307, "end" : 1321, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2047, "end" : 2070, "location-fragments" : [ { "start" : 2047, "end" : 2070, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 907, "end" : 929, "location-fragments" : [ { "start" : 907, "end" : 929, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1788, "end" : 1821, "location-fragments" : [ { "start" : 1788, "end" : 1821, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 310, "end" : 354, "location-fragments" : [ { "start" : 310, "end" : 354, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12618", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1341, "end" : 2049, "hmmStart" : 911, "hmmEnd" : 1449, "hmmLength" : 1450, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1329, "envelopeEnd" : 2050, "location-fragments" : [ { "start" : 1341, "end" : 2049, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-45, "familyName" : "FAMILY NOT NAMED", "score" : 158.7, "model-ac" : "PTHR12618" } ], "xref" : [ { "name" : "XP_018910051.1 PREDICTED: serine/arginine repetitive matrix protein 2-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910051.1" } ] },{ "sequence" : "MSDVQYSYTKKRADFGRHCNFGNSTKLMVENIQPNKALCEEYIRKDPVDKSTQHTKQFALHELNTIRAEYESTHINHVEGGWPKDVNYLDVEHTLRFRKKIEKDEMYIHTVLQLSHPMEHVIHQNNAINIYELYFSDIEEGKAMEKISSRTINVFRDPNTVKRPVQHLSWSPDGGTRLAVTHANLEFQRAPHDLCTHSYIWEVENPNSPDLVLKPKTTILSLEYHPKDPHCLVSGFCSGQVGAWDTRKGSEPCELSNMTNSHRDPVLKVLWINSKSGTEFFSASTDGQMKWWDTRKLDAPLETLLIDLTKGDEQLLSRSLGISALEYDASIPIRFMIGTETGIVISGNRKGKTTLEKLTAQFKAHQGPVYALHRNPSFVKNFLSVGDWTAKIWTEDCRESAIIWTSNYRHLLTNGAWSPTKYSVFYTTSMDGSLDAWDILNQQREPSLSVKMFDRESRREKIIEAKLREQRLKSKAAAKLAAGAGALLKETKPHIQINKDDQLVIQAEEEFFAILAEQKEMQDEYAEKLASVLHSTVGKDEKKGIKEKESKESKAAKQEADDETKGKE", "md5" : "f34ecb79c7995e0262de01d418d76342", "matches" : [ { "signature" : { "accession" : "PTHR12442:SF7", "name" : "DYNEIN INTERMEDIATE CHAIN 2, AXONEMAL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4, "end" : 451, "hmmStart" : 3, "hmmEnd" : 450, "hmmLength" : 573, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 452, "location-fragments" : [ { "start" : 4, "end" : 451, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-192, "familyName" : "DYNEIN INTERMEDIATE CHAIN 2, AXONEMAL", "score" : 641.7, "model-ac" : "PTHR12442:SF7" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 259, "end" : 295, "score" : 8.704, "alignment" : "TNSHRDPVLKVLWINSksGTEFFSASTDGQMKWWDTR-------", "location-fragments" : [ { "start" : 259, "end" : 295, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "PTHR12442", "name" : "DYNEIN INTERMEDIATE CHAIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4, "end" : 451, "hmmStart" : 3, "hmmEnd" : 450, "hmmLength" : 573, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 452, "location-fragments" : [ { "start" : 4, "end" : 451, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-192, "familyName" : "DYNEIN INTERMEDIATE CHAIN 2, AXONEMAL", "score" : 641.7, "model-ac" : "PTHR12442" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 125, "end" : 321, "hmmStart" : 204, "hmmEnd" : 330, "hmmLength" : 401, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-19, "score" : 71.6, "envelopeStart" : 125, "envelopeEnd" : 321, "postProcessed" : true, "location-fragments" : [ { "start" : 125, "end" : 321, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-27, "score" : 97.9, "model-ac" : "4pswB00" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 349, "end" : 459, "hmmStart" : 133, "hmmEnd" : 227, "hmmLength" : 318, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-7, "score" : 33.1, "envelopeStart" : 349, "envelopeEnd" : 459, "postProcessed" : true, "location-fragments" : [ { "start" : 349, "end" : 459, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.0E-27, "score" : 96.0, "model-ac" : "4g56D00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 539, "end" : 568, "location-fragments" : [ { "start" : 539, "end" : 568, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50294", "name" : "WD_REPEATS_REGION", "description" : "Trp-Asp (WD) repeats circular profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR017986", "name" : "WD40_repeat_dom", "description" : "WD40-repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 200, "end" : 447, "score" : 10.917, "alignment" : "------------------------------IWEVENPNSPDLVLKPKTTILSLEYHPKdPHCLVSGFCSGQVGAWDTRKGSEPCElsnmTNSHRDPVLKVLWINSksGTEFFSASTDGQMKWWDTRKLDAPLEtllidltkgdeqLLSRSLGISALEYDASiPIRFMIGTETGIVISGNRKGKTTLEKltaqFKAHQGPVYALHRNPSFVKNFLSVGDWTAKIWTEDCRESAIIwTSNYRHLLTNGAWSPTkYSVFYTTSMDGSLDAWDILNQQREPS", "location-fragments" : [ { "start" : 200, "end" : 447, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50294" }, { "signature" : { "accession" : "SSF50978", "name" : "WD40 repeat-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036322", "name" : "WD40_repeat_dom_sf", "description" : "WD40-repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 160, "end" : 450, "hmmLength" : 340, "location-fragments" : [ { "start" : 160, "end" : 450, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.02E-30, "model-ac" : "0049784" }, { "signature" : { "accession" : "SM00320", "name" : "WD40_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 399, "end" : 438, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 94.0, "score" : 4.5, "location-fragments" : [ { "start" : 399, "end" : 438, "dc-status" : "CONTINUOUS" } ] }, { "start" : 251, "end" : 293, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 0.19, "score" : 20.8, "location-fragments" : [ { "start" : 251, "end" : 293, "dc-status" : "CONTINUOUS" } ] }, { "start" : 355, "end" : 394, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 0.52, "score" : 18.8, "location-fragments" : [ { "start" : 355, "end" : 394, "dc-status" : "CONTINUOUS" } ] }, { "start" : 206, "end" : 245, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 1.4, "score" : 16.0, "location-fragments" : [ { "start" : 206, "end" : 245, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-13, "score" : 60.2, "model-ac" : "SM00320" } ], "xref" : [ { "name" : "XP_018910150.1 PREDICTED: dynein intermediate chain 2, axonemal [Bemisia tabaci]", "id" : "XP_018910150.1" } ] },{ "sequence" : "MIVSLFDWNSMLPLVSLLLLATQTANGKIEVAVGQSEYRTFCHTEAPHYDSASQSLFFVDTYVGKVCRHHLKWNATYCTCSLDHVLGSVVPVSNQPDWYIIGLGPYSAKMYWDGYIPHAEVHILGRHDEDAGAGTVFNDGKADCAQRLFMDTKGNASLFHYTKQSCNFEKDIDNEDGAIYNGIAWNSASDKLFLAETARAVIYSFDYNIEIGKISNRSVLFDFKANNVNGLPDGMAMDVDDNLWVAAIFGSYVYQISTRDGTLLRAVKMPARDVTSVIWGGPKLDTLFVTSSQHNLNDEEKRQQPRAGSVFAVRGLGTKGRRGNNAAICTAGCAEDGCTRSRCGQEVASPPASEFQVEGCLSSQGHSLSSDETHFYFGDFKRKAIQD", "md5" : "464b78f0f30e461e28bc8cd9876d8db1", "matches" : [ { "signature" : { "accession" : "PTHR10907", "name" : "REGUCALCIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 40, "end" : 327, "hmmStart" : 30, "hmmEnd" : 319, "hmmLength" : 323, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 16, "envelopeEnd" : 331, "location-fragments" : [ { "start" : 40, "end" : 327, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.8E-67, "familyName" : "REGUCALCIN", "score" : 228.2, "model-ac" : "PTHR10907" }, { "signature" : { "accession" : "PR01791", "name" : "REGUCALCIN", "description" : "Regucalcin signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR008367", "name" : "Regucalcin", "description" : "Regucalcin", "type" : "FAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "enzyme regulator activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030234" } ], "pathwayXRefs" : [ { "name" : "L-ascorbate biosynthesis VI (engineered pathway)", "databaseName" : "MetaCyc", "id" : "PWY-7165" }, { "name" : "Pentose phosphate pathway", "databaseName" : "KEGG", "id" : "00030+3.1.1.17" }, { "name" : "Ascorbate and aldarate metabolism", "databaseName" : "KEGG", "id" : "00053+3.1.1.17" }, { "name" : "Caprolactam degradation", "databaseName" : "KEGG", "id" : "00930+3.1.1.17" }, { "name" : "Sorbitol biosynthesis II", "databaseName" : "MetaCyc", "id" : "PWY-5530" }, { "name" : "Entner-Doudoroff pathway III (semi-phosphorylative)", "databaseName" : "MetaCyc", "id" : "PWY-2221" } ] } }, "locations" : [ { "start" : 257, "end" : 270, "pvalue" : 0.0117, "score" : 33.33, "motifNumber" : 3, "location-fragments" : [ { "start" : 257, "end" : 270, "dc-status" : "CONTINUOUS" } ] }, { "start" : 218, "end" : 236, "pvalue" : 0.0398, "score" : 27.49, "motifNumber" : 2, "location-fragments" : [ { "start" : 218, "end" : 236, "dc-status" : "CONTINUOUS" } ] }, { "start" : 304, "end" : 320, "pvalue" : 3.28E-9, "score" : 56.86, "motifNumber" : 4, "location-fragments" : [ { "start" : 304, "end" : 320, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-6, "graphscan" : ".iII", "model-ac" : "PR01791" }, { "signature" : { "accession" : "PR01790", "name" : "SMP30FAMILY", "description" : "Senescence marker protein-30 (SMP30) family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR005511", "name" : "SMP-30", "description" : "Senescence marker protein-30 (SMP-30)", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 231, "end" : 248, "pvalue" : 1.0E-7, "score" : 49.18, "motifNumber" : 5, "location-fragments" : [ { "start" : 231, "end" : 248, "dc-status" : "CONTINUOUS" } ] }, { "start" : 44, "end" : 61, "pvalue" : 6.71E-6, "score" : 41.77, "motifNumber" : 1, "location-fragments" : [ { "start" : 44, "end" : 61, "dc-status" : "CONTINUOUS" } ] }, { "start" : 128, "end" : 149, "pvalue" : 2.31E-4, "score" : 34.34, "motifNumber" : 2, "location-fragments" : [ { "start" : 128, "end" : 149, "dc-status" : "CONTINUOUS" } ] }, { "start" : 274, "end" : 292, "pvalue" : 7.76E-9, "score" : 42.3, "motifNumber" : 6, "location-fragments" : [ { "start" : 274, "end" : 292, "dc-status" : "CONTINUOUS" } ] }, { "start" : 189, "end" : 209, "pvalue" : 0.0035, "score" : 16.93, "motifNumber" : 4, "location-fragments" : [ { "start" : 189, "end" : 209, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-21, "graphscan" : "II.iII", "model-ac" : "PR01790" }, { "signature" : { "accession" : "G3DSA:2.120.10.30", "name" : "TolB", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011042", "name" : "6-blade_b-propeller_TolB-like", "description" : "Six-bladed beta-propeller, TolB-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 30, "end" : 327, "hmmStart" : 17, "hmmEnd" : 304, "hmmLength" : 311, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-69, "score" : 235.3, "envelopeStart" : 30, "envelopeEnd" : 327, "postProcessed" : true, "location-fragments" : [ { "start" : 30, "end" : 327, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-70, "score" : 238.4, "model-ac" : "5gtqA00" }, { "signature" : { "accession" : "SSF63829", "name" : "Calcium-dependent phosphotriesterase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 41, "end" : 320, "hmmLength" : 319, "location-fragments" : [ { "start" : 41, "end" : 320, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.98E-34, "model-ac" : "0052427" }, { "signature" : { "accession" : "PF08450", "name" : "SGL", "description" : "SMP-30/Gluconolactonase/LRE-like region", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013658", "name" : "SGL", "description" : "SMP-30/Gluconolactonase/LRE-like region", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 292, "hmmStart" : 2, "hmmEnd" : 245, "hmmLength" : 246, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-39, "score" : 135.8, "envelopeStart" : 43, "envelopeEnd" : 293, "postProcessed" : true, "location-fragments" : [ { "start" : 44, "end" : 292, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-41, "score" : 141.5, "model-ac" : "PF08450" } ], "xref" : [ { "name" : "XP_018909888.1 PREDICTED: regucalcin-like [Bemisia tabaci]", "id" : "XP_018909888.1" } ] },{ "sequence" : "MTTNNYFGFTHGTQYSATPGTTYPTQQTGYSVTPGATAAAYPTQRTATGYETYQTQATPTAYAVPAGATTATTYDYGYARTAHSSPTAYDAKAYYQQQANPATPVTPAYSTSDYQTAGAAIVKPQYSATYSTQTTPQRQVVPPKPAVSAVQYSQYAPPQQQQQTPAQAVSSYTASYSTPASIQPTSQLNKAIGSAPRAITQRAPQQAVQQQTTGYQYTQRHPFKPQQQQQQQPPPQQVSQVQQLSQLQQQQQQQQHQQVQQQHAQLQQQQQQQQQQQQQQQVQQQQIKKPYQASPVSNVGSYQVNNPSTAQAAFVAQSTAAATNSNYNKPKPGYDTALFNAASHYINQQSGPNQNKPFYKKSFGNNASGLKNLRPKAPPKSQQLHYCEVCKISCAGPLTYREHLEGQKHKKKEAALKSDAPAPTISRGPISLHCDLCAVTCTGQDAYGAHIRGNKHQKVLKLHAMLGKPVPDIPEDPKIVVAKSIAAAKANQNTTAPDGKKTVVVPPKVNFVQSGSLSTTTKPEPKAEGKENTKSESTPEPKTEDIEMAAATLLENEVTPVGHEFVEEIKDELGKLVSFNCKLCECKFNDPNAKEMHMKGRRHRLAFKKKVNPNLQVDVKPSFNKKKHFEEKTRRTGGGGGPREEFMRGNQRNMHWQDRMMEVEERMYWDERRRFEEEMEFMEWGRRFHGPGMMPPPFPPGPGPRMMGPPFMPPPPPPQFPRRLDTSDDRHVIARHAAVYPNEQELKALQKIVSHTEKALKLVSDFLTENAQSTTDKKNGTSEVKTEVKVEPKTAESPAKPNATPNKKGPQKTKEDGRDGSLFSFEKETEERVLKGVMRVESLAKGLLLHGDTHVKLVVLCSEKPTRALLVKVAANLPSQLSIVAPEDSYLTNMKSEEAAITVQTKTEPKLTVSVILTSPLLREQVNAAGSDAPAAQSTPDPPDLLNKKKCLDALAALRHAKWFQARVAGMQNCLMIIRIFRDLCQRVPTWAPFSPWAMELLCEKALSSAGMPLSPGDSLRRVLEAVSSGVILQNGPGILDPCEKEPVDAAANLTPQQREDITASAQHALRLLAFRQIHKVLGMEPLPAPPPMPTNKFNNRGGYNRFGRKRRRDNSSGENTDSDAGVNEKKDKKDTDVVIKVEGAKVSSPAAATTPAKPAEAAKAPAATPAAAKGSLKSPAAAKPAVKK", "md5" : "0e0909d0baa7cc61269ff22da4016c85", "matches" : [ { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 581, "end" : 603, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M5I1M", "alignment" : "CklCeckFndpnakemHmkgrrH", "location-fragments" : [ { "start" : 581, "end" : 603, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 151, "end" : 170, "location-fragments" : [ { "start" : 151, "end" : 170, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00355", "name" : "c2h2final6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 432, "end" : 456, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 7.0, "score" : 14.7, "location-fragments" : [ { "start" : 432, "end" : 456, "dc-status" : "CONTINUOUS" } ] }, { "start" : 385, "end" : 409, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 5.7, "score" : 15.5, "location-fragments" : [ { "start" : 385, "end" : 409, "dc-status" : "CONTINUOUS" } ] }, { "start" : 579, "end" : 603, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.66, "score" : 19.0, "location-fragments" : [ { "start" : 579, "end" : 603, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-10, "score" : 49.2, "model-ac" : "SM00355" }, { "signature" : { "accession" : "PF07528", "name" : "DZF", "description" : "DZF domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006561", "name" : "DZF_dom", "description" : "DZF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 839, "end" : 1089, "hmmStart" : 1, "hmmEnd" : 247, "hmmLength" : 248, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.2E-66, "score" : 222.8, "envelopeStart" : 839, "envelopeEnd" : 1090, "postProcessed" : true, "location-fragments" : [ { "start" : 839, "end" : 1089, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-66, "score" : 223.6, "model-ac" : "PF07528" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 559, "end" : 610, "hmmLength" : 72, "location-fragments" : [ { "start" : 559, "end" : 610, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.48E-8, "model-ac" : "0053677" }, { "signature" : { "accession" : "SM00572", "name" : "rich3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006561", "name" : "DZF_dom", "description" : "DZF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 833, "end" : 1090, "hmmStart" : 1, "hmmEnd" : 263, "hmmLength" : 263, "hmmBounds" : "COMPLETE", "evalue" : 7.9E-126, "score" : 434.0, "location-fragments" : [ { "start" : 833, "end" : 1090, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-126, "score" : 434.0, "model-ac" : "SM00572" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1109, "end" : 1141, "location-fragments" : [ { "start" : 1109, "end" : 1141, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 774, "end" : 823, "location-fragments" : [ { "start" : 774, "end" : 823, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51703", "name" : "DZF", "description" : "DZF domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR006561", "name" : "DZF_dom", "description" : "DZF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 709, "end" : 1117, "score" : 95.983, "alignment" : "PPFM-PPPPPPQFPRRLDTSDDRHVIARHAAVYPNEQELKALQKIVSHTEKALKLVSDFLTENAQSTTDKKngtsevktevkvepktaespakpnatpnkkgpqktkedgrdGSLFSFEKETEERVLKGVMRVESLAKGLLLHGDTHVKLVVLCSEKPTRALLVKVAANLPSQLSIvapEDSYLTNMKSEEAAITVQTKtepkltvsviltspllREQVNAAGSDAPAAQSTPDPPDLLNKKKCLDALAALRHAKWFQARVAGMQNCLMIIRIFRDLCQRVPTWAPFSPWAMELLCEKALSSAGMPLSPGDSLRRVLEAVSSGVILQNGPGILDPCEKEPVDAAANLTPQQREDITASAQHALRLLAFRQIHKVLGMEPLPAPPPMPTNKFNN------RGGYNRFGRKRRRDNSS", "location-fragments" : [ { "start" : 709, "end" : 1117, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51703" }, { "signature" : { "accession" : "PTHR45762:SF5", "name" : "ZINC-FINGER PROTEIN AT 72D, ISOFORM B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 151, "end" : 1136, "hmmStart" : 1, "hmmEnd" : 793, "hmmLength" : 807, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 149, "envelopeEnd" : 1147, "location-fragments" : [ { "start" : 151, "end" : 1136, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-261, "familyName" : "ZINC-FINGER PROTEIN AT 72D, ISOFORM B", "score" : 872.3, "model-ac" : "PTHR45762:SF5" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 809, "end" : 823, "location-fragments" : [ { "start" : 809, "end" : 823, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00451", "name" : "ZnF_U1_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003604", "name" : "Matrin/U1-like-C_Znf_C2H2", "description" : "Matrin/U1-C-like, C2H2-type zinc finger", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 429, "end" : 463, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 37, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-4, "score" : 30.7, "location-fragments" : [ { "start" : 429, "end" : 463, "dc-status" : "CONTINUOUS" } ] }, { "start" : 576, "end" : 610, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 37, "hmmBounds" : "COMPLETE", "evalue" : 0.0012, "score" : 28.1, "location-fragments" : [ { "start" : 576, "end" : 610, "dc-status" : "CONTINUOUS" } ] }, { "start" : 382, "end" : 416, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 37, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-7, "score" : 39.6, "location-fragments" : [ { "start" : 382, "end" : 416, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.5E-25, "score" : 98.4, "model-ac" : "SM00451" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 780, "end" : 794, "location-fragments" : [ { "start" : 780, "end" : 794, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 152, "end" : 170, "location-fragments" : [ { "start" : 152, "end" : 170, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 372, "end" : 417, "hmmLength" : 72, "location-fragments" : [ { "start" : 372, "end" : 417, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.55E-10, "model-ac" : "0053677" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1085, "end" : 1189, "location-fragments" : [ { "start" : 1085, "end" : 1189, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 185, "end" : 243, "location-fragments" : [ { "start" : 185, "end" : 243, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF12874", "name" : "zf-met", "description" : "Zinc-finger of C2H2 type", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 579, "end" : 603, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-5, "score" : 25.0, "envelopeStart" : 579, "envelopeEnd" : 603, "postProcessed" : true, "location-fragments" : [ { "start" : 579, "end" : 603, "dc-status" : "CONTINUOUS" } ] }, { "start" : 433, "end" : 456, "hmmStart" : 2, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.5E-4, "score" : 22.0, "envelopeStart" : 432, "envelopeEnd" : 456, "postProcessed" : true, "location-fragments" : [ { "start" : 433, "end" : 456, "dc-status" : "CONTINUOUS" } ] }, { "start" : 386, "end" : 409, "hmmStart" : 2, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.6E-6, "score" : 27.2, "envelopeStart" : 385, "envelopeEnd" : 409, "postProcessed" : true, "location-fragments" : [ { "start" : 386, "end" : 409, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-18, "score" : 65.9, "model-ac" : "PF12874" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 514, "end" : 544, "location-fragments" : [ { "start" : 514, "end" : 544, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 429, "end" : 469, "hmmStart" : 18, "hmmEnd" : 56, "hmmLength" : 60, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-8, "score" : 35.7, "envelopeStart" : 429, "envelopeEnd" : 469, "postProcessed" : true, "location-fragments" : [ { "start" : 429, "end" : 469, "dc-status" : "CONTINUOUS" } ] }, { "start" : 570, "end" : 612, "hmmStart" : 18, "hmmEnd" : 48, "hmmLength" : 60, "hmmBounds" : "COMPLETE", "evalue" : 3.2E-6, "score" : 28.5, "envelopeStart" : 570, "envelopeEnd" : 612, "postProcessed" : true, "location-fragments" : [ { "start" : 570, "end" : 612, "dc-status" : "CONTINUOUS" } ] }, { "start" : 376, "end" : 419, "hmmStart" : 15, "hmmEnd" : 50, "hmmLength" : 60, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-11, "score" : 45.2, "envelopeStart" : 376, "envelopeEnd" : 419, "postProcessed" : true, "location-fragments" : [ { "start" : 376, "end" : 419, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-23, "score" : 83.8, "model-ac" : "2mknA00" }, { "signature" : { "accession" : "PTHR45762", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 151, "end" : 1136, "hmmStart" : 1, "hmmEnd" : 793, "hmmLength" : 807, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 149, "envelopeEnd" : 1147, "location-fragments" : [ { "start" : 151, "end" : 1136, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-261, "familyName" : "ZINC-FINGER PROTEIN AT 72D, ISOFORM B", "score" : 872.3, "model-ac" : "PTHR45762" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 524, "end" : 543, "location-fragments" : [ { "start" : 524, "end" : 543, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 249, "end" : 288, "location-fragments" : [ { "start" : 249, "end" : 288, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 432, "end" : 465, "hmmLength" : 72, "location-fragments" : [ { "start" : 432, "end" : 465, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.27E-6, "model-ac" : "0053677" } ], "xref" : [ { "name" : "XP_018909580.1 PREDICTED: zinc finger RNA-binding protein-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909580.1" } ] },{ "sequence" : "MDDKIPPTIRALDETVVNRIAAGEVIQRPANALKELLENSLDAKSTNIQITLKAGGLKLLQIQDNGTGIRKEDLSIVCKRFTTSKLSSFEDLNTIATFGFRGEALASISHVAHLTIITKTSLEPCAYKCTYEDGNLIGTPKMIAGNQGTTIIVEDLFYNIATRKKALKNPSEEFAKVADVVSKYAVHNPKVGFCLKKQGESLTDIRTHPNSTHVDNIKAIYGTNVARELLEVDLEDEKMKIKFKGFISNANYATKKPHFLLFINHRLVDSTALRKALENIYSLYLAKNSYPFMYLSLELDPRNVDVNVHPTKHEVFFLHEEVIIEKVKSAIEAKLAGADHSRAFYLKSKFLPSKPMIPSKEENPVKNKDKEAPVAPCKMVRTDPKAQKMDKFLLPSQSSDCDKDSQPKKVIAPAFKKTSSSNAQRREINLTSVLTLRRVIEEQCSVTLREIFNQATYVGCTKPHWLLFQSTTNLFCANIQTIMSEAFYQILLYEFGNFGAIKYSEPMNIKELLLLGLELDEAKKYLEDGPAEEVVPKALAKLKKRALMLDDYFSLEMDEDQNLITIPLLLDDYIPPQEGLPMYLLRLAFEVDWTSEIECFRTFCRVTAEYYGSFKYLTRSSNWQKLVEHTFFPVVKSQFLPPMNFSDNKCLLLIEDIQNLYKVFERC", "md5" : "39c5acdfe6e33d56749b25772cae2085", "matches" : [ { "signature" : { "accession" : "PF16413", "name" : "Mlh1_C", "description" : "DNA mismatch repair protein Mlh1 C-terminus", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR032189", "name" : "Mlh1_C", "description" : "DNA mismatch repair protein Mlh1, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "TP53 Regulates Transcription of DNA Repair Genes", "databaseName" : "Reactome", "id" : "R-HSA-6796648" }, { "name" : "Defective Mismatch Repair Associated With PMS2", "databaseName" : "Reactome", "id" : "R-HSA-5632987" }, { "name" : "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)", "databaseName" : "Reactome", "id" : "R-HSA-5358565" }, { "name" : "Meiotic recombination", "databaseName" : "Reactome", "id" : "R-HSA-912446" }, { "name" : "Defective Mismatch Repair Associated With MLH1", "databaseName" : "Reactome", "id" : "R-HSA-5545483" }, { "name" : "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)", "databaseName" : "Reactome", "id" : "R-HSA-5358606" } ] } }, "locations" : [ { "start" : 429, "end" : 667, "hmmStart" : 1, "hmmEnd" : 269, "hmmLength" : 269, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-71, "score" : 240.0, "envelopeStart" : 429, "envelopeEnd" : 667, "postProcessed" : true, "location-fragments" : [ { "start" : 429, "end" : 667, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-72, "score" : 243.9, "model-ac" : "PF16413" }, { "signature" : { "accession" : "PF13589", "name" : "HATPase_c_3", "description" : "Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 30, "end" : 132, "hmmStart" : 4, "hmmEnd" : 106, "hmmLength" : 137, "hmmBounds" : "INCOMPLETE", "evalue" : 6.3E-14, "score" : 52.1, "envelopeStart" : 26, "envelopeEnd" : 137, "postProcessed" : true, "location-fragments" : [ { "start" : 30, "end" : 132, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-14, "score" : 53.0, "model-ac" : "PF13589" }, { "signature" : { "accession" : "SSF55874", "name" : "ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036890", "name" : "HATPase_C_sf", "description" : "Histidine kinase/HSP90-like ATPase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 222, "hmmLength" : 218, "location-fragments" : [ { "start" : 8, "end" : 222, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.15E-50, "model-ac" : "0035364" }, { "signature" : { "accession" : "cd16926", "name" : "HATPase_MutL-MLH-PMS-like", "description" : "HATPase_MutL-MLH-PMS-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 203, "sites" : [ { "description" : "ATP-lid", "numLocations" : 2, "siteLocations" : [ { "start" : 78, "end" : 78, "residue" : "C" }, { "start" : 105, "end" : 105, "residue" : "L" } ] }, { "description" : "Mg binding site", "numLocations" : 1, "siteLocations" : [ { "start" : 39, "end" : 39, "residue" : "N" } ] }, { "description" : "ATP binding site", "numLocations" : 24, "siteLocations" : [ { "start" : 43, "end" : 43, "residue" : "A" }, { "start" : 151, "end" : 151, "residue" : "I" }, { "start" : 118, "end" : 118, "residue" : "T" }, { "start" : 66, "end" : 66, "residue" : "G" }, { "start" : 103, "end" : 103, "residue" : "E" }, { "start" : 84, "end" : 84, "residue" : "S" }, { "start" : 102, "end" : 102, "residue" : "G" }, { "start" : 149, "end" : 149, "residue" : "T" }, { "start" : 40, "end" : 40, "residue" : "S" }, { "start" : 105, "end" : 105, "residue" : "L" }, { "start" : 68, "end" : 68, "residue" : "G" }, { "start" : 83, "end" : 83, "residue" : "T" }, { "start" : 148, "end" : 148, "residue" : "G" }, { "start" : 104, "end" : 104, "residue" : "A" }, { "start" : 116, "end" : 116, "residue" : "I" }, { "start" : 69, "end" : 69, "residue" : "I" }, { "start" : 85, "end" : 85, "residue" : "K" }, { "start" : 42, "end" : 42, "residue" : "D" }, { "start" : 77, "end" : 77, "residue" : "V" }, { "start" : 82, "end" : 82, "residue" : "T" }, { "start" : 39, "end" : 39, "residue" : "N" }, { "start" : 64, "end" : 64, "residue" : "D" }, { "start" : 35, "end" : 35, "residue" : "E" }, { "start" : 62, "end" : 62, "residue" : "I" } ] } ], "evalue" : 5.63747E-99, "score" : 299.352, "location-fragments" : [ { "start" : 16, "end" : 203, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd16926" }, { "signature" : { "accession" : "PS00058", "name" : "DNA_MISMATCH_REPAIR_1", "description" : "DNA mismatch repair proteins mutL / hexB / PMS1 signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR014762", "name" : "DNA_mismatch_repair_CS", "description" : "DNA mismatch repair, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 99, "end" : 105, "level" : "STRONG", "cigarAlignment" : "7M", "alignment" : "GFRGEAL", "location-fragments" : [ { "start" : 99, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00058" }, { "signature" : { "accession" : "PF01119", "name" : "DNA_mis_repair", "description" : "DNA mismatch repair protein, C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013507", "name" : "DNA_mismatch_S5_2-like", "description" : "DNA mismatch repair protein, S5 domain 2-like", "type" : "DOMAIN", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 217, "end" : 335, "hmmStart" : 1, "hmmEnd" : 118, "hmmLength" : 119, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.3E-34, "score" : 118.4, "envelopeStart" : 217, "envelopeEnd" : 336, "postProcessed" : true, "location-fragments" : [ { "start" : 217, "end" : 335, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-35, "score" : 119.3, "model-ac" : "PF01119" }, { "signature" : { "accession" : "TIGR00585", "name" : "TIGR00585", "description" : "mutl: DNA mismatch repair protein MutL", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR002099", "name" : "DNA_mismatch_repair_N", "description" : "DNA mismatch repair protein family, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 315, "hmmStart" : 2, "hmmEnd" : 312, "hmmLength" : 313, "hmmBounds" : "INCOMPLETE", "evalue" : 1.0E-103, "score" : 345.3, "envelopeStart" : 7, "envelopeEnd" : 316, "postProcessed" : false, "location-fragments" : [ { "start" : 8, "end" : 315, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-104, "score" : 345.9, "model-ac" : "TIGR00585" }, { "signature" : { "accession" : "SM01340", "name" : "DNA_mis_repair_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013507", "name" : "DNA_mismatch_S5_2-like", "description" : "DNA mismatch repair protein, S5 domain 2-like", "type" : "DOMAIN", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 217, "end" : 336, "hmmStart" : 1, "hmmEnd" : 161, "hmmLength" : 161, "hmmBounds" : "COMPLETE", "evalue" : 1.0E-46, "score" : 171.2, "location-fragments" : [ { "start" : 217, "end" : 336, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-46, "score" : 171.2, "model-ac" : "SM01340" }, { "signature" : { "accession" : "PTHR10073:SF12", "name" : "DNA MISMATCH REPAIR PROTEIN MLH1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 6, "end" : 663, "hmmStart" : 5, "hmmEnd" : 678, "hmmLength" : 678, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 3, "envelopeEnd" : 663, "location-fragments" : [ { "start" : 6, "end" : 663, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-212, "familyName" : "DNA MISMATCH REPAIR PROTEIN MLH1", "score" : 710.2, "model-ac" : "PTHR10073:SF12" }, { "signature" : { "accession" : "cd03483", "name" : "MutL_Trans_MLH1", "description" : "MutL_Trans_MLH1", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 214, "end" : 336, "sites" : [ { "description" : "ATP binding site", "numLocations" : 1, "siteLocations" : [ { "start" : 312, "end" : 312, "residue" : "K" } ] } ], "evalue" : 3.46115E-58, "score" : 190.138, "location-fragments" : [ { "start" : 214, "end" : 336, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd03483" }, { "signature" : { "accession" : "G3DSA:3.30.565.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036890", "name" : "HATPase_C_sf", "description" : "Histidine kinase/HSP90-like ATPase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 221, "hmmStart" : 2, "hmmEnd" : 214, "hmmLength" : 214, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-80, "score" : 270.7, "envelopeStart" : 8, "envelopeEnd" : 221, "postProcessed" : true, "location-fragments" : [ { "start" : 8, "end" : 221, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-80, "score" : 271.2, "model-ac" : "4p7aA01" }, { "signature" : { "accession" : "SSF54211", "name" : "Ribosomal protein S5 domain 2-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR020568", "name" : "Ribosomal_S5_D2-typ_fold", "description" : "Ribosomal protein S5 domain 2-type fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 200, "end" : 335, "hmmLength" : 134, "location-fragments" : [ { "start" : 200, "end" : 335, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-33, "model-ac" : "0038464" }, { "signature" : { "accession" : "G3DSA:3.30.230.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR014721", "name" : "Ribosomal_S5_D2-typ_fold_subgr", "description" : "Ribosomal protein S5 domain 2-type fold, subgroup", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 222, "end" : 348, "hmmStart" : 2, "hmmEnd" : 124, "hmmLength" : 127, "hmmBounds" : "COMPLETE", "evalue" : 3.4E-46, "score" : 158.1, "envelopeStart" : 222, "envelopeEnd" : 348, "postProcessed" : true, "location-fragments" : [ { "start" : 222, "end" : 348, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-46, "score" : 159.1, "model-ac" : "4p7aA02" }, { "signature" : { "accession" : "PTHR10073", "name" : "DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR038973", "name" : "MutL/Mlh/Pms", "description" : "DNA mismatch repair protein MutL/Mlh/Pms", "type" : "FAMILY", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "ATPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016887" }, { "name" : "mismatch repair complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0032300" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 663, "hmmStart" : 5, "hmmEnd" : 678, "hmmLength" : 678, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 3, "envelopeEnd" : 663, "location-fragments" : [ { "start" : 6, "end" : 663, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-212, "familyName" : "DNA MISMATCH REPAIR PROTEIN MLH1", "score" : 710.2, "model-ac" : "PTHR10073" } ], "xref" : [ { "name" : "XP_018910086.1 PREDICTED: DNA mismatch repair protein Mlh1 [Bemisia tabaci]", "id" : "XP_018910086.1" } ] },{ "sequence" : "MIGHSISKCPSRPKRHILQQLCLATRSVKEGCSKPPTVGLPTTSSLSSKFGSLASDHVRQSSSVLPTQAQVVICGSGVVANSVAYHLVQHGWTDVLVIDQGSICGGTSNFGSGTLGLFKPIDERHIISNSIKLYRQLQEMGHDIGLKQVGSVNLAQTKDRIIMLKRRIAYNLPTGLHCEIIGPNELQKLHPHICTDNILGGVWVPEDAVVDTLSVCRVLAKLAKQGGASYVENCIVEKISTENNCIKSVTTNRGDVDCEYFVNCAGMWARELGLKSEPKVRIPVYPAEHYYAKTTPISGISDNLPYIRDFDSHIYMREYNGGFLVGGFEPQAKPAFLGHKGVPGDWKKQLPADWDHFKPLWQNAIQRLPILKDVPEPSLMNYPDTFTPNGKWILGETPEVDNYFVAVGMNGNSLQGAGGIGKALAEWIVEGEPTQELLKFDVQRFLDLHNNRNYLQQRIQEVVGRHYSIMYPSQSEFQLARKLRCSPLYSVLEKRGAVFGMRMGYERPLYFDSSYQPGQPLPTMPPGTFFKPKFFDYLLEEYYACREGVGVIDMSSFSKIKIKSGYIPGSHIQAQTPRNVVDWLQRLCSNDVNIPVGGIVHTGMQNERGGYENDCILVREAENSFFMVSPTSQQTRVFEWLRRHLPTDHSVSLNDVTSMYTVINVVGPKARQLLSELSNVDIDLQPFTYKKVNVGYASDVMMMSFTHTGEPGFCLYIPSEYALHVYQQLAAVGVDYGLRDVGTITQRWMRIEKFIPLWGEDLNSFTTPFECGSGYRVKLDNDYFMGKFALQKQKEQGVKKRLVLFQLEGIDPDKDVWAWGSEPIYRDSEFVGIVTSAGFGFTLGKLVCMGYIRRPGQSRRHERLDGHHNDQIVTNQFIMSTSARYEIDIAGQRVLAKPQIYAPKATSINPSSAGLETPYVPKVVISHSNNP", "md5" : "785c3334e35b2f07ab10040c022dd6ce", "matches" : [ { "signature" : { "accession" : "G3DSA:3.50.50.60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036188", "name" : "FAD/NAD-bd_sf", "description" : "FAD/NAD(P)-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 71, "end" : 446, "hmmStart" : 1, "hmmEnd" : 388, "hmmLength" : 243, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.7E-113, "score" : 381.6, "envelopeStart" : 71, "envelopeEnd" : 447, "postProcessed" : true, "location-fragments" : [ { "start" : 71, "end" : 147, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 207, "end" : 283, "dc-status" : "NC_TERMINAL_DISC" }, { "start" : 388, "end" : 446, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.2E-113, "score" : 382.1, "model-ac" : "1pj5A01" }, { "signature" : { "accession" : "G3DSA:3.30.1360.120", "name" : "Probable tRNA modification gtpase trme; domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR027266", "name" : "TrmE/GcvT_dom1", "description" : "GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 481, "end" : 765, "hmmStart" : 1, "hmmEnd" : 307, "hmmLength" : 198, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.1E-100, "score" : 338.5, "envelopeStart" : 481, "envelopeEnd" : 790, "postProcessed" : true, "location-fragments" : [ { "start" : 481, "end" : 556, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 656, "end" : 765, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 9.6E-102, "score" : 342.0, "model-ac" : "1pj5A03" }, { "signature" : { "accession" : "G3DSA:2.40.30.110", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 798, "end" : 897, "hmmStart" : 2, "hmmEnd" : 74, "hmmLength" : 77, "hmmBounds" : "COMPLETE", "evalue" : 2.6E-19, "score" : 70.5, "envelopeStart" : 798, "envelopeEnd" : 897, "postProcessed" : true, "location-fragments" : [ { "start" : 798, "end" : 897, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-19, "score" : 71.6, "model-ac" : "4pabA05" }, { "signature" : { "accession" : "PF08669", "name" : "GCV_T_C", "description" : "Glycine cleavage T-protein C-terminal barrel domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013977", "name" : "GCV_T_C", "description" : "Glycine cleavage T-protein, C-terminal barrel domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "One carbon pool by folate", "databaseName" : "KEGG", "id" : "00670+2.1.2.10" }, { "name" : "Glycine, serine and threonine metabolism", "databaseName" : "KEGG", "id" : "00260+2.1.2.10" } ] } }, "locations" : [ { "start" : 800, "end" : 897, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 80, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.2E-13, "score" : 49.4, "envelopeStart" : 800, "envelopeEnd" : 900, "postProcessed" : true, "location-fragments" : [ { "start" : 800, "end" : 897, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-13, "score" : 50.8, "model-ac" : "PF08669" }, { "signature" : { "accession" : "PF01571", "name" : "GCV_T", "description" : "Aminomethyltransferase folate-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006222", "name" : "GCV_T_N", "description" : "Aminomethyltransferase, folate-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 488, "end" : 774, "hmmStart" : 1, "hmmEnd" : 254, "hmmLength" : 256, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 7.3E-68, "score" : 228.7, "envelopeStart" : 488, "envelopeEnd" : 776, "postProcessed" : true, "location-fragments" : [ { "start" : 488, "end" : 774, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-68, "score" : 229.6, "model-ac" : "PF01571" }, { "signature" : { "accession" : "SSF51905", "name" : "FAD/NAD(P)-binding domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036188", "name" : "FAD/NAD-bd_sf", "description" : "FAD/NAD(P)-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 69, "end" : 472, "hmmLength" : 306, "location-fragments" : [ { "start" : 69, "end" : 282, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 388, "end" : 472, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 5.5E-48, "model-ac" : "0048771" }, { "signature" : { "accession" : "SSF103025", "name" : "Folate-binding domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 481, "end" : 798, "hmmLength" : 315, "location-fragments" : [ { "start" : 481, "end" : 798, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.21E-74, "model-ac" : "0042338" }, { "signature" : { "accession" : "PTHR13847:SF257", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 60, "end" : 860, "hmmStart" : 59, "hmmEnd" : 859, "hmmLength" : 924, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 41, "envelopeEnd" : 919, "location-fragments" : [ { "start" : 60, "end" : 860, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-183, "familyName" : "", "score" : 614.1, "model-ac" : "PTHR13847:SF257" }, { "signature" : { "accession" : "SSF101790", "name" : "Aminomethyltransferase beta-barrel domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029043", "name" : "GcvT/YgfZ_C", "description" : "Glycine cleavage T-protein/YgfZ, C-terminal", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 801, "end" : 854, "hmmLength" : 88, "location-fragments" : [ { "start" : 801, "end" : 854, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.74E-12, "model-ac" : "0042335" }, { "signature" : { "accession" : "PF01266", "name" : "DAO", "description" : "FAD dependent oxidoreductase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006076", "name" : "FAD-dep_OxRdtase", "description" : "FAD dependent oxidoreductase", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" }, { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 71, "end" : 427, "hmmStart" : 2, "hmmEnd" : 353, "hmmLength" : 353, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.1E-54, "score" : 184.9, "envelopeStart" : 70, "envelopeEnd" : 427, "postProcessed" : true, "location-fragments" : [ { "start" : 71, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-54, "score" : 185.6, "model-ac" : "PF01266" }, { "signature" : { "accession" : "G3DSA:3.30.70.1400", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 557, "end" : 790, "hmmStart" : 1, "hmmEnd" : 307, "hmmLength" : 120, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.1E-100, "score" : 338.5, "envelopeStart" : 481, "envelopeEnd" : 790, "postProcessed" : true, "location-fragments" : [ { "start" : 766, "end" : 790, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 557, "end" : 655, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 9.6E-102, "score" : 342.0, "model-ac" : "1pj5A04" }, { "signature" : { "accession" : "G3DSA:3.30.9.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 148, "end" : 387, "hmmStart" : 1, "hmmEnd" : 388, "hmmLength" : 178, "hmmBounds" : "INCOMPLETE", "evalue" : 1.7E-113, "score" : 381.6, "envelopeStart" : 71, "envelopeEnd" : 447, "postProcessed" : true, "location-fragments" : [ { "start" : 148, "end" : 206, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 284, "end" : 387, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.2E-113, "score" : 382.1, "model-ac" : "1pj5A02" }, { "signature" : { "accession" : "PTHR13847", "name" : "FAD NAD BINDING OXIDOREDUCTASES", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 60, "end" : 860, "hmmStart" : 59, "hmmEnd" : 859, "hmmLength" : 924, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 41, "envelopeEnd" : 919, "location-fragments" : [ { "start" : 60, "end" : 860, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-183, "familyName" : "", "score" : 614.1, "model-ac" : "PTHR13847" }, { "signature" : { "accession" : "PF16350", "name" : "FAO_M", "description" : "FAD dependent oxidoreductase central domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR032503", "name" : "FAO_M", "description" : "FAD dependent oxidoreductase, central domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 430, "end" : 486, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 56, "hmmBounds" : "COMPLETE", "evalue" : 4.1E-17, "score" : 62.2, "envelopeStart" : 430, "envelopeEnd" : 486, "postProcessed" : true, "location-fragments" : [ { "start" : 430, "end" : 486, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-17, "score" : 63.2, "model-ac" : "PF16350" }, { "signature" : { "accession" : "SSF54373", "name" : "FAD-linked reductases, C-terminal domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 284, "end" : 387, "hmmLength" : 119, "location-fragments" : [ { "start" : 284, "end" : 387, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.47E-23, "model-ac" : "0042337" } ], "xref" : [ { "name" : "XP_018910548.1 PREDICTED: pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910548.1" } ] },{ "sequence" : "MEGTVFTPNMEVAEFQDFAKAMIDYISKYMSTIRDRPVLPKLEPGYLRPLIPESAPEEPESWHNVMEDIERVIMPGVTHWHSPRFHAYFPTACSYPAIVADMLSDAIACIGFTWIASPACTELEVVMMDWLGKMLNLPDDFLASGKKGGGGVIQGTASEATLVALLGAKTRAIRRTKEQHPDWTDLEIASKLVAYCSKQAHSSVERAGLLGSVPFRLLPTDDMYRLQGSTLEEAIKKDKADGLVPFYVVATLGTTSCCSFDLLKEIGPVCKNEEVWLHVDAAYAGSAFICPEYQYLLEGVEYAESFNFNPHKWMLVNFDCSAMWLKNPDEVVNAFNVDPLYLKHDHQGAAPDYRHWQIPLGRRFRSLKLWFVLRLYGIKNLQTHIRHQIGLAHQFEAYVNEDEEFELFNEVLMGLVCFRVKGSNELNEQVLNRINKKGKIHMVPSKIKDVFFLRFAVCSRFTNAEDVKYSWSEVKATTQEIKKELAKQ", "md5" : "c1fb565810b6184931450afcf4edfa93", "matches" : [ { "signature" : { "accession" : "cd06450", "name" : "DOPA_deC_like", "description" : "DOPA_deC_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 85, "end" : 476, "sites" : [ { "description" : "catalytic residue", "numLocations" : 1, "siteLocations" : [ { "start" : 312, "end" : 312, "residue" : "K" } ] }, { "description" : "pyridoxal 5'-phosphate binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 251, "end" : 251, "residue" : "T" }, { "start" : 158, "end" : 158, "residue" : "S" }, { "start" : 309, "end" : 309, "residue" : "N" }, { "start" : 161, "end" : 161, "residue" : "T" }, { "start" : 312, "end" : 312, "residue" : "K" }, { "start" : 283, "end" : 283, "residue" : "Y" }, { "start" : 280, "end" : 280, "residue" : "D" }, { "start" : 157, "end" : 157, "residue" : "A" } ] } ], "evalue" : 1.64451E-132, "score" : 385.403, "location-fragments" : [ { "start" : 85, "end" : 476, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd06450" }, { "signature" : { "accession" : "PR00800", "name" : "YHDCRBOXLASE", "description" : "Aromatic-L-amino-acid decarboxylase signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR010977", "name" : "Aromatic_deC", "description" : "Aromatic-L-amino-acid decarboxylase", "type" : "FAMILY", "goXRefs" : [ { "name" : "carboxy-lyase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016831" }, { "name" : "cellular amino acid metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006520" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 149, "end" : 169, "pvalue" : 6.55E-15, "score" : 69.12, "motifNumber" : 7, "location-fragments" : [ { "start" : 149, "end" : 169, "dc-status" : "CONTINUOUS" } ] }, { "start" : 103, "end" : 121, "pvalue" : 9.18E-11, "score" : 66.77, "motifNumber" : 5, "location-fragments" : [ { "start" : 103, "end" : 121, "dc-status" : "CONTINUOUS" } ] }, { "start" : 82, "end" : 101, "pvalue" : 5.78E-12, "score" : 58.71, "motifNumber" : 4, "location-fragments" : [ { "start" : 82, "end" : 101, "dc-status" : "CONTINUOUS" } ] }, { "start" : 15, "end" : 34, "pvalue" : 1.43E-7, "score" : 38.29, "motifNumber" : 1, "location-fragments" : [ { "start" : 15, "end" : 34, "dc-status" : "CONTINUOUS" } ] }, { "start" : 56, "end" : 75, "pvalue" : 4.92E-11, "score" : 49.43, "motifNumber" : 3, "location-fragments" : [ { "start" : 56, "end" : 75, "dc-status" : "CONTINUOUS" } ] }, { "start" : 38, "end" : 55, "pvalue" : 8.97E-11, "score" : 60.0, "motifNumber" : 2, "location-fragments" : [ { "start" : 38, "end" : 55, "dc-status" : "CONTINUOUS" } ] }, { "start" : 122, "end" : 141, "pvalue" : 7.6E-11, "score" : 69.43, "motifNumber" : 6, "location-fragments" : [ { "start" : 122, "end" : 141, "dc-status" : "CONTINUOUS" } ] }, { "start" : 359, "end" : 374, "pvalue" : 2.97E-10, "score" : 82.32, "motifNumber" : 8, "location-fragments" : [ { "start" : 359, "end" : 374, "dc-status" : "CONTINUOUS" } ] }, { "start" : 402, "end" : 421, "pvalue" : 4.86E-10, "score" : 52.29, "motifNumber" : 9, "location-fragments" : [ { "start" : 402, "end" : 421, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-86, "graphscan" : "IIIIIIIII", "model-ac" : "PR00800" }, { "signature" : { "accession" : "PTHR11999:SF144", "name" : "MIP05841P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 486, "hmmStart" : 1, "hmmEnd" : 478, "hmmLength" : 559, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 10, "envelopeEnd" : 488, "location-fragments" : [ { "start" : 10, "end" : 486, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-223, "familyName" : "MIP05841P", "score" : 745.3, "model-ac" : "PTHR11999:SF144" }, { "signature" : { "accession" : "PF00282", "name" : "Pyridoxal_deC", "description" : "Pyridoxal-dependent decarboxylase conserved domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002129", "name" : "PyrdxlP-dep_de-COase", "description" : "Pyridoxal phosphate-dependent decarboxylase", "type" : "FAMILY", "goXRefs" : [ { "name" : "carboxy-lyase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016831" }, { "name" : "pyridoxal phosphate binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030170" }, { "name" : "carboxylic acid metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0019752" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 421, "hmmStart" : 1, "hmmEnd" : 375, "hmmLength" : 375, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-163, "score" : 543.2, "envelopeStart" : 44, "envelopeEnd" : 421, "postProcessed" : true, "location-fragments" : [ { "start" : 44, "end" : 421, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-163, "score" : 543.5, "model-ac" : "PF00282" }, { "signature" : { "accession" : "G3DSA:1.20.1340.10", "name" : "dopa decarboxylase", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 90, "hmmStart" : 1, "hmmEnd" : 81, "hmmLength" : 81, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-35, "score" : 122.8, "envelopeStart" : 10, "envelopeEnd" : 90, "postProcessed" : true, "location-fragments" : [ { "start" : 10, "end" : 90, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.1E-36, "score" : 124.5, "model-ac" : "3k40A01" }, { "signature" : { "accession" : "PS00392", "name" : "DDC_GAD_HDC_YDC", "description" : "DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR021115", "name" : "Pyridoxal-P_BS", "description" : "Pyridoxal-phosphate binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "carboxy-lyase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016831" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 305, "end" : 326, "level" : "STRONG", "cigarAlignment" : "2M1I1M3I3M1I1M1I3M2I2M1I1M", "alignment" : "SFnFnphKWMlVnFDCsaMWlK", "location-fragments" : [ { "start" : 305, "end" : 326, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00392" }, { "signature" : { "accession" : "G3DSA:3.90.1150.10", "name" : "Aspartate Aminotransferase", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015422", "name" : "PyrdxlP-dep_Trfase_dom1", "description" : "Pyridoxal phosphate-dependent transferase domain 1", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 387, "end" : 485, "hmmStart" : 3, "hmmEnd" : 97, "hmmLength" : 99, "hmmBounds" : "COMPLETE", "evalue" : 3.5E-35, "score" : 121.8, "envelopeStart" : 387, "envelopeEnd" : 485, "postProcessed" : true, "location-fragments" : [ { "start" : 387, "end" : 485, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-35, "score" : 123.6, "model-ac" : "3k40A03" }, { "signature" : { "accession" : "SSF53383", "name" : "PLP-dependent transferases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR015424", "name" : "PyrdxlP-dep_Trfase", "description" : "Pyridoxal phosphate-dependent transferase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 482, "hmmLength" : 476, "location-fragments" : [ { "start" : 10, "end" : 482, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.43E-150, "model-ac" : "0047670" }, { "signature" : { "accession" : "G3DSA:3.40.640.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015421", "name" : "PyrdxlP-dep_Trfase_major", "description" : "Pyridoxal phosphate-dependent transferase, major domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 91, "end" : 386, "hmmStart" : 3, "hmmEnd" : 295, "hmmLength" : 295, "hmmBounds" : "COMPLETE", "evalue" : 4.3E-118, "score" : 395.4, "envelopeStart" : 91, "envelopeEnd" : 386, "postProcessed" : true, "location-fragments" : [ { "start" : 91, "end" : 386, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-118, "score" : 395.7, "model-ac" : "3k40A02" }, { "signature" : { "accession" : "PTHR11999", "name" : "GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 486, "hmmStart" : 1, "hmmEnd" : 478, "hmmLength" : 559, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 10, "envelopeEnd" : 488, "location-fragments" : [ { "start" : 10, "end" : 486, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-223, "familyName" : "MIP05841P", "score" : 745.3, "model-ac" : "PTHR11999" } ], "xref" : [ { "name" : "XP_018910259.1 PREDICTED: aromatic-L-amino-acid decarboxylase isoform X1 [Bemisia tabaci]", "id" : "XP_018910259.1" } ] },{ "sequence" : "MTLAMSGSLHKFRMLIAWFPILVLPVLASYARAKPEEAEEVSQTSATRDGLSDASLYDQSEPATSPACDTSADSDIESVLQEQLPPENDSWPSDEDLSDYDPDDWADGQHRREKRQAEGQNNDPLDFLEHLDPKRAKPAFNSWGGKRTSSFHSWGGKRSSEDSIDALEETKRNDPFIILKFADSLYNTNGGFKRRPSFNSWGGKRAGTAAFNSWSGKRAGAAAFNSWGGKRGPNFNSWGGKRAPPKPAFNSWGGKRGPAFNSWGGKRGPAFNSWGGKRANFNSWGGKRGPAFNSWGGKRSPAFKSWGGKRANFNSWGGKRANFNSWGGKRSPAFNSWGGKRAPAFNSWGGKRAASGSTYNAQGGKRGPAFYSWGGKRSSNENYNLGQENKETGILELVKEPGNLDQPISLNKREATKSTAPEAGPSDKNSDNTHTLVKREVDSREGNLDPSIAAVEKLYRDFKEREKKCAKSKSIVHGERVKHLLNYILNLRLSDREPEEKKSVIHKMLLRAADYSPDSSTFTQSRRGAEFHSWGGKRSEVNSAWYGHD", "md5" : "a5a94db146712fd5725a3229c96c3ce6", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 39, "end" : 142, "location-fragments" : [ { "start" : 39, "end" : 142, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 399, "end" : 439, "location-fragments" : [ { "start" : 399, "end" : 439, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 409, "end" : 431, "location-fragments" : [ { "start" : 409, "end" : 431, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 103, "end" : 136, "location-fragments" : [ { "start" : 103, "end" : 136, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 44, "end" : 88, "location-fragments" : [ { "start" : 44, "end" : 88, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910201.1 PREDICTED: protein RNA-directed DNA methylation 3-like [Bemisia tabaci]", "id" : "XP_018910201.1" } ] },{ "sequence" : "MASIKVPEQKVILCGEYGVGKSSLFRRYAYDTFVSGSSRQLTLGLDHYNKEYRINDKSIGLQLWDTGGMERVASITSSYYKFAEAAILVFSLDNAASFHVLSQHLLEIVTYAENAKIFLCGNKMDLEGSTPQVTEADMESFCEQCHNLISATYKTSCKTGEGVEEMFRDIAYHLVQSNRSRIELQSVDVNAFKIAPAEEVTEPSCLC", "md5" : "c62855c4dcb19cc525925bc9e3de617f", "matches" : [ { "signature" : { "accession" : "PF00071", "name" : "Ras", "description" : "Ras family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001806", "name" : "Small_GTPase", "description" : "Small GTPase", "type" : "FAMILY", "goXRefs" : [ { "name" : "GTPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003924" }, { "name" : "GTP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005525" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 173, "hmmStart" : 1, "hmmEnd" : 159, "hmmLength" : 162, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.0E-35, "score" : 120.5, "envelopeStart" : 10, "envelopeEnd" : 176, "postProcessed" : true, "location-fragments" : [ { "start" : 10, "end" : 173, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-35, "score" : 120.7, "model-ac" : "PF00071" }, { "signature" : { "accession" : "PTHR24073:SF382", "name" : "RABX6, ISOFORM B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 193, "hmmStart" : 32, "hmmEnd" : 238, "hmmLength" : 497, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 205, "location-fragments" : [ { "start" : 7, "end" : 193, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-73, "familyName" : "RABX6, ISOFORM B", "score" : 249.9, "model-ac" : "PTHR24073:SF382" }, { "signature" : { "accession" : "SM00174", "name" : "rho_sub_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 177, "hmmStart" : 1, "hmmEnd" : 180, "hmmLength" : 180, "hmmBounds" : "COMPLETE", "evalue" : 3.1E-5, "score" : -50.4, "location-fragments" : [ { "start" : 11, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-5, "score" : -50.4, "model-ac" : "SM00174" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 184, "hmmLength" : 204, "location-fragments" : [ { "start" : 8, "end" : 184, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.46E-41, "model-ac" : "0044416" }, { "signature" : { "accession" : "cd00154", "name" : "Rab", "description" : "Rab", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 171, "sites" : [ { "description" : "Rab family motif 2 (RabF2)", "numLocations" : 5, "siteLocations" : [ { "start" : 60, "end" : 60, "residue" : "G" }, { "start" : 63, "end" : 63, "residue" : "L" }, { "start" : 62, "end" : 62, "residue" : "Q" }, { "start" : 61, "end" : 61, "residue" : "L" }, { "start" : 64, "end" : 64, "residue" : "W" } ] }, { "description" : "GEF interaction site", "numLocations" : 10, "siteLocations" : [ { "start" : 46, "end" : 46, "residue" : "D" }, { "start" : 44, "end" : 44, "residue" : "G" }, { "start" : 50, "end" : 50, "residue" : "K" }, { "start" : 60, "end" : 60, "residue" : "G" }, { "start" : 45, "end" : 45, "residue" : "L" }, { "start" : 47, "end" : 47, "residue" : "H" }, { "start" : 48, "end" : 48, "residue" : "Y" }, { "start" : 49, "end" : 49, "residue" : "N" }, { "start" : 58, "end" : 58, "residue" : "S" }, { "start" : 51, "end" : 51, "residue" : "E" } ] }, { "description" : "G4 box", "numLocations" : 4, "siteLocations" : [ { "start" : 122, "end" : 122, "residue" : "N" }, { "start" : 123, "end" : 123, "residue" : "K" }, { "start" : 125, "end" : 125, "residue" : "D" }, { "start" : 124, "end" : 124, "residue" : "M" } ] }, { "description" : "Rab family motif 3 (RabF3)", "numLocations" : 5, "siteLocations" : [ { "start" : 73, "end" : 73, "residue" : "A" }, { "start" : 76, "end" : 76, "residue" : "T" }, { "start" : 75, "end" : 75, "residue" : "I" }, { "start" : 71, "end" : 71, "residue" : "R" }, { "start" : 72, "end" : 72, "residue" : "V" } ] }, { "description" : "G1 box", "numLocations" : 8, "siteLocations" : [ { "start" : 20, "end" : 20, "residue" : "G" }, { "start" : 22, "end" : 22, "residue" : "S" }, { "start" : 18, "end" : 18, "residue" : "G" }, { "start" : 15, "end" : 15, "residue" : "G" }, { "start" : 21, "end" : 21, "residue" : "K" }, { "start" : 17, "end" : 17, "residue" : "Y" }, { "start" : 16, "end" : 16, "residue" : "E" }, { "start" : 19, "end" : 19, "residue" : "V" } ] }, { "description" : "G3 box", "numLocations" : 4, "siteLocations" : [ { "start" : 68, "end" : 68, "residue" : "G" }, { "start" : 65, "end" : 65, "residue" : "D" }, { "start" : 66, "end" : 66, "residue" : "T" }, { "start" : 67, "end" : 67, "residue" : "G" } ] }, { "description" : "G2 box", "numLocations" : 1, "siteLocations" : [ { "start" : 42, "end" : 42, "residue" : "T" } ] }, { "description" : "Switch I region", "numLocations" : 8, "siteLocations" : [ { "start" : 33, "end" : 33, "residue" : "F" }, { "start" : 46, "end" : 46, "residue" : "D" }, { "start" : 44, "end" : 44, "residue" : "G" }, { "start" : 45, "end" : 45, "residue" : "L" }, { "start" : 47, "end" : 47, "residue" : "H" }, { "start" : 48, "end" : 48, "residue" : "Y" }, { "start" : 43, "end" : 43, "residue" : "L" }, { "start" : 42, "end" : 42, "residue" : "T" } ] }, { "description" : "GTP/Mg2+ binding site", "numLocations" : 16, "siteLocations" : [ { "start" : 122, "end" : 122, "residue" : "N" }, { "start" : 18, "end" : 18, "residue" : "G" }, { "start" : 23, "end" : 23, "residue" : "S" }, { "start" : 42, "end" : 42, "residue" : "T" }, { "start" : 123, "end" : 123, "residue" : "K" }, { "start" : 125, "end" : 125, "residue" : "D" }, { "start" : 33, "end" : 33, "residue" : "F" }, { "start" : 20, "end" : 20, "residue" : "G" }, { "start" : 68, "end" : 68, "residue" : "G" }, { "start" : 22, "end" : 22, "residue" : "S" }, { "start" : 156, "end" : 156, "residue" : "S" }, { "start" : 21, "end" : 21, "residue" : "K" }, { "start" : 158, "end" : 158, "residue" : "K" }, { "start" : 17, "end" : 17, "residue" : "Y" }, { "start" : 19, "end" : 19, "residue" : "V" }, { "start" : 157, "end" : 157, "residue" : "C" } ] }, { "description" : "Rab family motif 1 (RabF1)", "numLocations" : 5, "siteLocations" : [ { "start" : 46, "end" : 46, "residue" : "D" }, { "start" : 44, "end" : 44, "residue" : "G" }, { "start" : 45, "end" : 45, "residue" : "L" }, { "start" : 47, "end" : 47, "residue" : "H" }, { "start" : 43, "end" : 43, "residue" : "L" } ] }, { "description" : "Rab family motif 4 (RabF4)", "numLocations" : 2, "siteLocations" : [ { "start" : 79, "end" : 79, "residue" : "Y" }, { "start" : 80, "end" : 80, "residue" : "Y" } ] }, { "description" : "G5 box", "numLocations" : 3, "siteLocations" : [ { "start" : 156, "end" : 156, "residue" : "S" }, { "start" : 158, "end" : 158, "residue" : "K" }, { "start" : 157, "end" : 157, "residue" : "C" } ] }, { "description" : "GDI interaction site", "numLocations" : 9, "siteLocations" : [ { "start" : 46, "end" : 46, "residue" : "D" }, { "start" : 44, "end" : 44, "residue" : "G" }, { "start" : 78, "end" : 78, "residue" : "S" }, { "start" : 65, "end" : 65, "residue" : "D" }, { "start" : 76, "end" : 76, "residue" : "T" }, { "start" : 43, "end" : 43, "residue" : "L" }, { "start" : 64, "end" : 64, "residue" : "W" }, { "start" : 77, "end" : 77, "residue" : "S" }, { "start" : 72, "end" : 72, "residue" : "V" } ] }, { "description" : "Switch II region", "numLocations" : 11, "siteLocations" : [ { "start" : 68, "end" : 68, "residue" : "G" }, { "start" : 78, "end" : 78, "residue" : "S" }, { "start" : 79, "end" : 79, "residue" : "Y" }, { "start" : 70, "end" : 70, "residue" : "E" }, { "start" : 73, "end" : 73, "residue" : "A" }, { "start" : 76, "end" : 76, "residue" : "T" }, { "start" : 80, "end" : 80, "residue" : "Y" }, { "start" : 75, "end" : 75, "residue" : "I" }, { "start" : 71, "end" : 71, "residue" : "R" }, { "start" : 77, "end" : 77, "residue" : "S" }, { "start" : 72, "end" : 72, "residue" : "V" } ] }, { "description" : "Rab subfamily motif 3 (RabSF3)", "numLocations" : 5, "siteLocations" : [ { "start" : 115, "end" : 115, "residue" : "A" }, { "start" : 118, "end" : 118, "residue" : "F" }, { "start" : 119, "end" : 119, "residue" : "L" }, { "start" : 117, "end" : 117, "residue" : "I" }, { "start" : 116, "end" : 116, "residue" : "K" } ] }, { "description" : "Rab family motif 5 (RabF5)", "numLocations" : 6, "siteLocations" : [ { "start" : 91, "end" : 91, "residue" : "S" }, { "start" : 89, "end" : 89, "residue" : "V" }, { "start" : 88, "end" : 88, "residue" : "L" }, { "start" : 90, "end" : 90, "residue" : "F" }, { "start" : 92, "end" : 92, "residue" : "L" }, { "start" : 93, "end" : 93, "residue" : "D" } ] }, { "description" : "Rab subfamily motif 2 (RabSF2)", "numLocations" : 11, "siteLocations" : [ { "start" : 25, "end" : 25, "residue" : "F" }, { "start" : 28, "end" : 28, "residue" : "Y" }, { "start" : 33, "end" : 33, "residue" : "F" }, { "start" : 27, "end" : 27, "residue" : "R" }, { "start" : 24, "end" : 24, "residue" : "L" }, { "start" : 23, "end" : 23, "residue" : "S" }, { "start" : 31, "end" : 31, "residue" : "D" }, { "start" : 30, "end" : 30, "residue" : "Y" }, { "start" : 26, "end" : 26, "residue" : "R" }, { "start" : 29, "end" : 29, "residue" : "A" }, { "start" : 32, "end" : 32, "residue" : "T" } ] }, { "description" : "effector interaction site", "numLocations" : 11, "siteLocations" : [ { "start" : 46, "end" : 46, "residue" : "D" }, { "start" : 79, "end" : 79, "residue" : "Y" }, { "start" : 62, "end" : 62, "residue" : "Q" }, { "start" : 45, "end" : 45, "residue" : "L" }, { "start" : 47, "end" : 47, "residue" : "H" }, { "start" : 84, "end" : 84, "residue" : "E" }, { "start" : 75, "end" : 75, "residue" : "I" }, { "start" : 43, "end" : 43, "residue" : "L" }, { "start" : 64, "end" : 64, "residue" : "W" }, { "start" : 71, "end" : 71, "residue" : "R" }, { "start" : 72, "end" : 72, "residue" : "V" } ] } ], "evalue" : 1.85396E-52, "score" : 163.781, "location-fragments" : [ { "start" : 10, "end" : 171, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00154" }, { "signature" : { "accession" : "TIGR00231", "name" : "TIGR00231", "description" : "small_GTP: small GTP-binding protein domain", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR005225", "name" : "Small_GTP-bd_dom", "description" : "Small GTP-binding protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "GTP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005525" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 9, "end" : 167, "hmmStart" : 4, "hmmEnd" : 159, "hmmLength" : 164, "hmmBounds" : "INCOMPLETE", "evalue" : 7.6E-20, "score" : 69.3, "envelopeStart" : 7, "envelopeEnd" : 171, "postProcessed" : false, "location-fragments" : [ { "start" : 9, "end" : 167, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-20, "score" : 69.7, "model-ac" : "TIGR00231" }, { "signature" : { "accession" : "PR00449", "name" : "RASTRNSFRMNG", "description" : "Transforming protein P21 ras signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : null }, "locations" : [ { "start" : 52, "end" : 74, "pvalue" : 5.74E-8, "score" : 36.29, "motifNumber" : 3, "location-fragments" : [ { "start" : 52, "end" : 74, "dc-status" : "CONTINUOUS" } ] }, { "start" : 152, "end" : 174, "pvalue" : 1.09E-5, "score" : 28.2, "motifNumber" : 5, "location-fragments" : [ { "start" : 152, "end" : 174, "dc-status" : "CONTINUOUS" } ] }, { "start" : 9, "end" : 30, "pvalue" : 6.26E-9, "score" : 39.83, "motifNumber" : 1, "location-fragments" : [ { "start" : 9, "end" : 30, "dc-status" : "CONTINUOUS" } ] }, { "start" : 113, "end" : 126, "pvalue" : 2.07E-6, "score" : 47.2, "motifNumber" : 4, "location-fragments" : [ { "start" : 113, "end" : 126, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-21, "graphscan" : "I.IIi", "model-ac" : "PR00449" }, { "signature" : { "accession" : "PS51419", "name" : "RAB", "description" : "small GTPase Rab1 family profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 207, "score" : 22.174, "alignment" : "SIKVpEQKVILCGEYGVGKSSLFRRYAYDTFvsGSSRQLTLGLDHYNKEYRINDKSIGLQLWDTGGMERVASITSSYYKFAEAAILVFSLDNAASFHVLSQHLLEIVTYA-ENAKIFLCGNKMDLeGSTPQVTEADMESFCEQChNliSATYKTSCKTGEGVEEMFRDIAYHLVQSNRSRIELQSvDVNAFKIAPAEEVTEPS--CLC", "location-fragments" : [ { "start" : 3, "end" : 207, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51419" }, { "signature" : { "accession" : "SM00173", "name" : "ras_sub_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 6, "end" : 177, "hmmStart" : 1, "hmmEnd" : 167, "hmmLength" : 167, "hmmBounds" : "COMPLETE", "evalue" : 1.0E-8, "score" : 10.4, "location-fragments" : [ { "start" : 6, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-8, "score" : 10.4, "model-ac" : "SM00173" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 200, "hmmStart" : 11, "hmmEnd" : 177, "hmmLength" : 219, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-47, "score" : 162.6, "envelopeStart" : 3, "envelopeEnd" : 200, "postProcessed" : true, "location-fragments" : [ { "start" : 3, "end" : 200, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-47, "score" : 162.9, "model-ac" : "3m1iA00" }, { "signature" : { "accession" : "PTHR24073", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 193, "hmmStart" : 32, "hmmEnd" : 238, "hmmLength" : 497, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 205, "location-fragments" : [ { "start" : 7, "end" : 193, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-73, "familyName" : "RABX6, ISOFORM B", "score" : 249.9, "model-ac" : "PTHR24073" }, { "signature" : { "accession" : "SM00175", "name" : "rab_sub_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 177, "hmmStart" : 1, "hmmEnd" : 172, "hmmLength" : 172, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-22, "score" : 91.0, "location-fragments" : [ { "start" : 9, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-22, "score" : 91.0, "model-ac" : "SM00175" } ], "xref" : [ { "name" : "XP_018909797.1 PREDICTED: ras-related protein Rab-30 [Bemisia tabaci]", "id" : "XP_018909797.1" } ] },{ "sequence" : "MSYDFKFPILLPKNHHFTRLVIDYYHDMTLHGGPSSTLAAINQRFWIINGRAVVRSKLQKCIQCFKVRPKFTQPLMGDLPKWRVQAAYPFLNTACDYGGPFQVKVNELRNARQTKGYLALFICMATKAVHLEFVSELTTKAFEGALARFVSRRGLCKNMFSDNGTNFVGMNNSLKELYAFLKTNETSIAENLCKKEINWHFQPASAPNFGGLHEAGIKSAKHHLKRIMGTQIFTFEEMTTLVTRVEAIMNSRPLCPLSTDPSDMDALTPGHFLVGRPLNALPEENLTETPSNRVDRWGLINKASQHFWQTWKNEYINCLRQRSKWTQETDPIKIDDLVIIQDNNLPP", "md5" : "1008262e6952072eaa4eb6be620268bf", "matches" : [ { "signature" : { "accession" : "PS50994", "name" : "INTEGRASE", "description" : "Integrase catalytic domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001584", "name" : "Integrase_cat-core", "description" : "Integrase, catalytic core", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA integration", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0015074" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 85, "end" : 277, "score" : 9.58, "alignment" : "QAAYPflntacdyGGPFQVKVNELRNARQTKGYLALFICMATKAVHLEFVSELTTKAFEGALARFVSRR-GLCKNMFSDNGTNFvgmnnslkelyaflktNETSIAENLCKKEINWHFQPASAPNFGGLHEAGIKSAKHHLKRIMGTQIftFEEMTTLVTRVEAIMNSRPLcplstdpSDMDALTPGHFLVGRP", "location-fragments" : [ { "start" : 85, "end" : 277, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50994" }, { "signature" : { "accession" : "G3DSA:3.30.420.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036397", "name" : "RNaseH_sf", "description" : "Ribonuclease H superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 83, "end" : 292, "hmmStart" : 11, "hmmEnd" : 148, "hmmLength" : 200, "hmmBounds" : "COMPLETE", "evalue" : 4.0E-6, "score" : 28.1, "envelopeStart" : 83, "envelopeEnd" : 292, "postProcessed" : true, "location-fragments" : [ { "start" : 83, "end" : 292, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-7, "score" : 30.3, "model-ac" : "2x78A00" }, { "signature" : { "accession" : "G3DSA:1.10.340.70", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 68, "hmmStart" : 41, "hmmEnd" : 89, "hmmLength" : 93, "hmmBounds" : "COMPLETE", "evalue" : 2.6E-5, "score" : 26.3, "envelopeStart" : 5, "envelopeEnd" : 68, "postProcessed" : true, "location-fragments" : [ { "start" : 5, "end" : 68, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-5, "score" : 27.6, "model-ac" : "3oymA01" }, { "signature" : { "accession" : "PF17921", "name" : "Integrase_H2C2", "description" : "Integrase zinc binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR041588", "name" : "Integrase_H2C2", "description" : "Integrase zinc-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 15, "end" : 69, "hmmStart" : 3, "hmmEnd" : 57, "hmmLength" : 58, "hmmBounds" : "INCOMPLETE", "evalue" : 2.7E-10, "score" : 40.1, "envelopeStart" : 13, "envelopeEnd" : 70, "postProcessed" : true, "location-fragments" : [ { "start" : 15, "end" : 69, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-10, "score" : 40.1, "model-ac" : "PF17921" }, { "signature" : { "accession" : "PF18701", "name" : "DUF5641", "description" : "Family of unknown function (DUF5641)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR040676", "name" : "DUF5641", "description" : "Domain of unknown function DUF5641", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 296, "end" : 347, "hmmStart" : 2, "hmmEnd" : 53, "hmmLength" : 94, "hmmBounds" : "INCOMPLETE", "evalue" : 1.3E-15, "score" : 57.3, "envelopeStart" : 295, "envelopeEnd" : 347, "postProcessed" : true, "location-fragments" : [ { "start" : 296, "end" : 347, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.2E-16, "score" : 58.1, "model-ac" : "PF18701" }, { "signature" : { "accession" : "SSF53098", "name" : "Ribonuclease H-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR012337", "name" : "RNaseH-like_sf", "description" : "Ribonuclease H-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 87, "end" : 261, "hmmLength" : 168, "location-fragments" : [ { "start" : 87, "end" : 261, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.22E-12, "model-ac" : "0046055" }, { "signature" : { "accession" : "PTHR22955", "name" : "RETROTRANSPOSON", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 49, "end" : 346, "hmmStart" : 1131, "hmmEnd" : 1418, "hmmLength" : 1437, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 347, "location-fragments" : [ { "start" : 49, "end" : 346, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-75, "familyName" : "RETROTRANSPOSON", "score" : 258.0, "model-ac" : "PTHR22955" } ], "xref" : [ { "name" : "XP_018910133.1 PREDICTED: uncharacterized protein LOC109039195 [Bemisia tabaci]", "id" : "XP_018910133.1" } ] },{ "sequence" : "MDQSCRILGFALSLLAHSVSTLESSVDRLELDTFKVYLGHESLRVNLDNPSHASPQDESLPGKIPSPIEIGVQLTSNGIALKNAKVLGQNKIGFGERTTVQLKNSKGEKRCVEVEWSTSNAKQTLEDCFHMRPHDWYGGAQQLDQYWPVQQAIFKEDSYVTKEFSHNRTHANIAEPYWFNSDGFMIYVDPTVPLFVDQNHHRNETLCLLAKHDAPYLRKGGPTLKYTMCKFENPRVAHEYAVKRFLGKPSGIPDTTMVQHPIWSTWAKYKTDIDEDVIMQFARQIVDNGFNNSQIEIDDMWQTCYGSVSFNETRFPNIKKLVTKLNKMGFRTTIWVPPVINLDCYIHEEATKKGYLVKNTEGNTTTFWWNGFGSYIDFTNPAAADWHEKRVRNMLRESGIDAPKFDAGESSWAPQIPVLSGPESEQPEIIVRNYVQLAAKFGPMVEVRTAKRTQNLPIFVRMHDRDAVWGLKHGLHSVITTVFQMNFNGYPFVLPDMVGGNLQMNDTADKEIFIRYLQTNVFLPTIQFSIPPWDYDNETIALSKRYTTLHYEYSGTIIELMKKAVETGQPINTPIWWVDPTNKETYGINTEYMLGEDILVAPVLEQGATSRDIYLPKGQWREEVKPDRPVVTGPTWLRNYPAPLDTLPYFTRVSSGAERLSLTVLLTVYIIGSFLLEFYFF", "md5" : "9559d131ce5c6be3daf8e1b6eb508929", "matches" : [ { "signature" : { "accession" : "PF01055", "name" : "Glyco_hydro_31", "description" : "Glycosyl hydrolases family 31", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000322", "name" : "Glyco_hydro_31", "description" : "Glycoside hydrolase family 31", "type" : "FAMILY", "goXRefs" : [ { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" }, { "name" : "hydrolase activity, hydrolyzing O-glycosyl compounds", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004553" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 244, "end" : 652, "hmmStart" : 17, "hmmEnd" : 438, "hmmLength" : 443, "hmmBounds" : "INCOMPLETE", "evalue" : 5.7E-45, "score" : 154.3, "envelopeStart" : 232, "envelopeEnd" : 655, "postProcessed" : true, "location-fragments" : [ { "start" : 244, "end" : 652, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-45, "score" : 154.3, "model-ac" : "PF01055" }, { "signature" : { "accession" : "cd06592", "name" : "GH31_NET37", "description" : "GH31_NET37", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 260, "end" : 620, "sites" : [ { "description" : "putative active site", "numLocations" : 9, "siteLocations" : [ { "start" : 406, "end" : 406, "residue" : "D" }, { "start" : 540, "end" : 540, "residue" : "I" }, { "start" : 299, "end" : 299, "residue" : "D" }, { "start" : 446, "end" : 446, "residue" : "E" }, { "start" : 298, "end" : 298, "residue" : "D" }, { "start" : 407, "end" : 407, "residue" : "A" }, { "start" : 542, "end" : 542, "residue" : "L" }, { "start" : 464, "end" : 464, "residue" : "D" }, { "start" : 404, "end" : 404, "residue" : "K" } ] }, { "description" : "catalytic site", "numLocations" : 2, "siteLocations" : [ { "start" : 406, "end" : 406, "residue" : "D" }, { "start" : 464, "end" : 464, "residue" : "D" } ] } ], "evalue" : 8.49847E-168, "score" : 482.874, "location-fragments" : [ { "start" : 260, "end" : 620, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd06592" }, { "signature" : { "accession" : "PTHR43053", "name" : "GLYCOSIDASE FAMILY 31", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 97, "end" : 653, "hmmStart" : 93, "hmmEnd" : 653, "hmmLength" : 655, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 62, "envelopeEnd" : 655, "location-fragments" : [ { "start" : 97, "end" : 653, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-197, "familyName" : "MYOGENESIS-REGULATING GLYCOSIDASE", "score" : 658.8, "model-ac" : "PTHR43053" }, { "signature" : { "accession" : "SSF51445", "name" : "(Trans)glycosidases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR017853", "name" : "Glycoside_hydrolase_SF", "description" : "Glycoside hydrolase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 260, "end" : 585, "hmmLength" : 348, "location-fragments" : [ { "start" : 260, "end" : 585, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.48E-69, "model-ac" : "0051664" }, { "signature" : { "accession" : "PTHR43053:SF4", "name" : "MYOGENESIS-REGULATING GLYCOSIDASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 97, "end" : 653, "hmmStart" : 93, "hmmEnd" : 653, "hmmLength" : 655, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 62, "envelopeEnd" : 655, "location-fragments" : [ { "start" : 97, "end" : 653, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-197, "familyName" : "MYOGENESIS-REGULATING GLYCOSIDASE", "score" : 658.8, "model-ac" : "PTHR43053:SF4" }, { "signature" : { "accession" : "G3DSA:2.60.40.1180", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013780", "name" : "Glyco_hydro_b", "description" : "Glycosyl hydrolase, all-beta", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 601, "end" : 652, "hmmStart" : 2, "hmmEnd" : 50, "hmmLength" : 51, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-7, "score" : 33.5, "envelopeStart" : 601, "envelopeEnd" : 652, "postProcessed" : true, "location-fragments" : [ { "start" : 601, "end" : 652, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-8, "score" : 34.8, "model-ac" : "4ba0A03" }, { "signature" : { "accession" : "G3DSA:3.20.20.80", "name" : "Glycosidases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 238, "end" : 600, "hmmStart" : 12, "hmmEnd" : 371, "hmmLength" : 371, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-64, "score" : 218.8, "envelopeStart" : 238, "envelopeEnd" : 600, "postProcessed" : true, "location-fragments" : [ { "start" : 238, "end" : 600, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-64, "score" : 219.7, "model-ac" : "2f2hA02" }, { "signature" : { "accession" : "SSF51011", "name" : "Glycosyl hydrolase domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 570, "end" : 652, "hmmLength" : 80, "location-fragments" : [ { "start" : 570, "end" : 652, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.09E-17, "model-ac" : "0052584" } ], "xref" : [ { "name" : "XP_018910486.1 PREDICTED: uncharacterized family 31 glucosidase KIAA1161-like [Bemisia tabaci]", "id" : "XP_018910486.1" } ] },{ "sequence" : "MFIYRKGLFNLSRVKMAVHLFYNLIAILLVITPAYSEFVDAESLDTYDIEGKVFPPIGYSMDISNWQADTKVMVKEGSYMGFLKEDGSFVVSNLPSGSYVLEVINPNFVYEPVRVEINSKGKIRARKVNYVQTSLVNQLPYPLKLKPLGQHRYFKIREQWRLTDFLFNPMVLMMVSPLLLIMILPRMLNDPETAKEMEQFNNLTNYDMPELSEAITSFLRGKTDKQKPKAIKSAKKGKPENSKQS", "md5" : "2d16a90b23310b4745be77dc60febdfb", "matches" : [ { "signature" : { "accession" : "PTHR13605:SF4", "name" : "ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 22, "end" : 226, "hmmStart" : 8, "hmmEnd" : 220, "hmmLength" : 221, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 12, "envelopeEnd" : 227, "location-fragments" : [ { "start" : 22, "end" : 226, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.6E-62, "familyName" : "ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7", "score" : 211.1, "model-ac" : "PTHR13605:SF4" }, { "signature" : { "accession" : "SSF49452", "name" : "Starch-binding domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR013784", "name" : "Carb-bd-like_fold", "description" : "Carbohydrate-binding-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "carbohydrate binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030246" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 122, "hmmLength" : 87, "location-fragments" : [ { "start" : 46, "end" : 122, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.32E-6, "model-ac" : "0048380" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 218, "end" : 245, "location-fragments" : [ { "start" : 218, "end" : 245, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR13605", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR039163", "name" : "EMC7", "description" : "ER membrane protein complex subunit 7", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 22, "end" : 226, "hmmStart" : 8, "hmmEnd" : 220, "hmmLength" : 221, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 12, "envelopeEnd" : 227, "location-fragments" : [ { "start" : 22, "end" : 226, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.6E-62, "familyName" : "ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7", "score" : 211.1, "model-ac" : "PTHR13605" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 220, "end" : 245, "location-fragments" : [ { "start" : 220, "end" : 245, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF09430", "name" : "DUF2012", "description" : "Protein of unknown function (DUF2012)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR019008", "name" : "DUF2012", "description" : "Domain of unknown function DUF2012", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 64, "end" : 173, "hmmStart" : 4, "hmmEnd" : 123, "hmmLength" : 123, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.7E-34, "score" : 117.9, "envelopeStart" : 61, "envelopeEnd" : 173, "postProcessed" : true, "location-fragments" : [ { "start" : 64, "end" : 173, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-34, "score" : 118.6, "model-ac" : "PF09430" } ], "xref" : [ { "name" : "XP_018909829.1 PREDICTED: ER membrane protein complex subunit 7 homolog [Bemisia tabaci]", "id" : "XP_018909829.1" }, { "name" : "XP_018909830.1 PREDICTED: ER membrane protein complex subunit 7 homolog [Bemisia tabaci]", "id" : "XP_018909830.1" } ] },{ "sequence" : "MEFASGNKWKAIIPLVMASVWSLFSLTEEHLTEKTRTPQVNMELDPHWDDFKSRYNKTFNRNTEAARRLAWEQNLIRIIQHNEEAAAGKHNYTLRDNHLSDMDPNTYAAKMIKLRHSGRRRRLPEETLGTPVHDPEKIPEEFDWREKGFETPAWNQEDCGACYAFAVSSTVSGQIFKEAGVLRYLSVQQIVDCSGNVGNLGCGGGSLRNTLKYIQGTGGLETYKDYPYKAKQDTCQFKKDKAVVRVISWAVLPPRDEHALKVAVWKVGPIAVSLNASPATFQLYHSGVYDDPECSSDFVNHAMLLVGYTKDSWILRNWWSDEWGEKGYMYLKRGANRCAISNYAAYAHIDKYSLKL", "md5" : "90c9ec9b01b6a840c520085ad9baf90c", "matches" : [ { "signature" : { "accession" : "cd02248", "name" : "Peptidase_C1A", "description" : "Peptidase_C1A", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR039417", "name" : "Peptidase_C1A_papain-like", "description" : "Papain-like cysteine endopeptidase", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 139, "end" : 347, "sites" : [ { "description" : "S2 subsite", "numLocations" : 6, "siteLocations" : [ { "start" : 206, "end" : 206, "residue" : "S" }, { "start" : 207, "end" : 207, "residue" : "L" }, { "start" : 343, "end" : 343, "residue" : "Y" }, { "start" : 273, "end" : 273, "residue" : "S" }, { "start" : 302, "end" : 302, "residue" : "A" }, { "start" : 299, "end" : 299, "residue" : "V" } ] }, { "description" : "active site", "numLocations" : 4, "siteLocations" : [ { "start" : 317, "end" : 317, "residue" : "N" }, { "start" : 156, "end" : 156, "residue" : "Q" }, { "start" : 162, "end" : 162, "residue" : "C" }, { "start" : 301, "end" : 301, "residue" : "H" } ] } ], "evalue" : 4.82021E-89, "score" : 264.486, "location-fragments" : [ { "start" : 139, "end" : 347, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd02248" }, { "signature" : { "accession" : "PF08246", "name" : "Inhibitor_I29", "description" : "Cathepsin propeptide inhibitor domain (I29)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013201", "name" : "Prot_inhib_I29", "description" : "Cathepsin propeptide inhibitor domain (I29)", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 48, "end" : 105, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 58, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.3E-8, "score" : 34.4, "envelopeStart" : 48, "envelopeEnd" : 107, "postProcessed" : true, "location-fragments" : [ { "start" : 48, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-8, "score" : 35.2, "model-ac" : "PF08246" }, { "signature" : { "accession" : "PF00112", "name" : "Peptidase_C1", "description" : "Papain family cysteine protease", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 138, "end" : 347, "hmmStart" : 1, "hmmEnd" : 217, "hmmLength" : 218, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.4E-57, "score" : 193.1, "envelopeStart" : 138, "envelopeEnd" : 348, "postProcessed" : true, "location-fragments" : [ { "start" : 138, "end" : 347, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-57, "score" : 193.6, "model-ac" : "PF00112" }, { "signature" : { "accession" : "SM00848", "name" : "Inhibitor_I29_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013201", "name" : "Prot_inhib_I29", "description" : "Cathepsin propeptide inhibitor domain (I29)", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 48, "end" : 107, "hmmStart" : 1, "hmmEnd" : 67, "hmmLength" : 67, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-14, "score" : 63.5, "location-fragments" : [ { "start" : 48, "end" : 107, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-14, "score" : 63.5, "model-ac" : "SM00848" }, { "signature" : { "accession" : "PS00139", "name" : "THIOL_PROTEASE_CYS", "description" : "Eukaryotic thiol (cysteine) proteases cysteine active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000169", "name" : "Pept_cys_AS", "description" : "Cysteine peptidase, cysteine active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 156, "end" : 167, "level" : "STRONG", "cigarAlignment" : "2M1I6M1I2M", "alignment" : "QEdCGACYAfAV", "location-fragments" : [ { "start" : 156, "end" : 167, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00139" }, { "signature" : { "accession" : "G3DSA:3.90.70.10", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 39, "end" : 349, "hmmStart" : 7, "hmmEnd" : 314, "hmmLength" : 316, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-89, "score" : 302.3, "envelopeStart" : 39, "envelopeEnd" : 349, "postProcessed" : true, "location-fragments" : [ { "start" : 39, "end" : 349, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-89, "score" : 302.6, "model-ac" : "1cs8A00" }, { "signature" : { "accession" : "PTHR12411", "name" : "CYSTEINE PROTEASE FAMILY C1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 34, "end" : 347, "hmmStart" : 15, "hmmEnd" : 334, "hmmLength" : 336, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 17, "envelopeEnd" : 349, "location-fragments" : [ { "start" : 34, "end" : 347, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-78, "familyName" : "CATHEPSIN L2", "score" : 266.1, "model-ac" : "PTHR12411" }, { "signature" : { "accession" : "SM00645", "name" : "pept_c1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 138, "end" : 348, "hmmStart" : 1, "hmmEnd" : 340, "hmmLength" : 340, "hmmBounds" : "COMPLETE", "evalue" : 3.1E-75, "score" : 265.9, "location-fragments" : [ { "start" : 138, "end" : 348, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-75, "score" : 265.9, "model-ac" : "SM00645" }, { "signature" : { "accession" : "PTHR12411:SF57", "name" : "CATHEPSIN L2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 34, "end" : 347, "hmmStart" : 15, "hmmEnd" : 334, "hmmLength" : 336, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 17, "envelopeEnd" : 349, "location-fragments" : [ { "start" : 34, "end" : 347, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-78, "familyName" : "CATHEPSIN L2", "score" : 266.1, "model-ac" : "PTHR12411:SF57" }, { "signature" : { "accession" : "SSF54001", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038765", "name" : "Papain-like_cys_pep_sf", "description" : "Papain-like cysteine peptidase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 40, "end" : 347, "hmmLength" : 316, "location-fragments" : [ { "start" : 40, "end" : 347, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.51E-90, "model-ac" : "0046209" } ], "xref" : [ { "name" : "XP_018910099.1 PREDICTED: cathepsin L1-like [Bemisia tabaci]", "id" : "XP_018910099.1" } ] },{ "sequence" : "MEQLDKLLQAAILFFVILSTINIEALYTYGAASDIFGEGKSDKEILDNLLLATRYDKRLLPPVVGTLTVNMSVLLLSLASPDESSLKYEVEFLLQQQWYDPRLTYSNQSKYDFLNAIHHHSDIWLPDTYFIMHGDFKDPLIPVHFALRIYRNGTVNYLMRRHLILSCQGRLHIFPFDDPLCSFAMESISYEQSAITYVWKNDEDTLRKSPSLTTLNAYLIQNQTIACPTKASWRGNYSCLKVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVAQGERKSDGPNDIVACTNCGPNTCTHTANNGCASEARRKEPPHPIRVAKTIDVIARITFPVAYSIFLIFFFIHYKGFQNNAEGIIIDSEPDAQPLKMPQPENTASTHQSNFDHQTTSHLSPFSSDTTPH", "md5" : "e1e68a43dc18bae4104b47139f32b684", "matches" : [ { "signature" : { "accession" : "SSF63712", "name" : "Nicotinic receptor ligand binding domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036734", "name" : "Neur_chan_lig-bd_sf", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 249, "hmmLength" : 205, "location-fragments" : [ { "start" : 42, "end" : 249, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.32E-39, "model-ac" : "0038932" }, { "signature" : { "accession" : "PF02932", "name" : "Neur_chan_memb", "description" : "Neurotransmitter-gated ion-channel transmembrane region", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006029", "name" : "Neurotrans-gated_channel_TM", "description" : "Neurotransmitter-gated ion-channel transmembrane domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 258, "end" : 344, "hmmStart" : 2, "hmmEnd" : 88, "hmmLength" : 238, "hmmBounds" : "INCOMPLETE", "evalue" : 1.4E-12, "score" : 48.2, "envelopeStart" : 257, "envelopeEnd" : 355, "postProcessed" : true, "location-fragments" : [ { "start" : 258, "end" : 344, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-15, "score" : 56.8, "model-ac" : "PF02932" }, { "signature" : { "accession" : "PTHR18945:SF819", "name" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 23, "end" : 63, "hmmStart" : 38, "hmmEnd" : 78, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 67, "location-fragments" : [ { "start" : 23, "end" : 63, "dc-status" : "CONTINUOUS" } ] }, { "start" : 358, "end" : 427, "hmmStart" : 417, "hmmEnd" : 494, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 346, "envelopeEnd" : 433, "location-fragments" : [ { "start" : 358, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-162, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 544.6, "model-ac" : "PTHR18945:SF819" }, { "signature" : { "accession" : "SSF90112", "name" : "Neurotransmitter-gated ion-channel transmembrane pore", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036719", "name" : "Neuro-gated_channel_TM_sf", "description" : "Neurotransmitter-gated ion-channel transmembrane domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 252, "end" : 430, "hmmLength" : 227, "location-fragments" : [ { "start" : 252, "end" : 430, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.27E-28, "model-ac" : "0041810" }, { "signature" : { "accession" : "cd19049", "name" : "LGIC_TM_anion", "description" : "LGIC_TM_anion", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 252, "end" : 341, "sites" : [ { "description" : "pentamer interface", "numLocations" : 34, "siteLocations" : [ { "start" : 298, "end" : 298, "residue" : "N" }, { "start" : 309, "end" : 309, "residue" : "N" }, { "start" : 332, "end" : 332, "residue" : "V" }, { "start" : 325, "end" : 325, "residue" : "Y" }, { "start" : 278, "end" : 278, "residue" : "A" }, { "start" : 279, "end" : 279, "residue" : "V" }, { "start" : 291, "end" : 291, "residue" : "L" }, { "start" : 321, "end" : 321, "residue" : "M" }, { "start" : 267, "end" : 267, "residue" : "S" }, { "start" : 274, "end" : 274, "residue" : "L" }, { "start" : 264, "end" : 264, "residue" : "L" }, { "start" : 281, "end" : 281, "residue" : "A" }, { "start" : 328, "end" : 328, "residue" : "L" }, { "start" : 336, "end" : 336, "residue" : "Y" }, { "start" : 270, "end" : 270, "residue" : "I" }, { "start" : 301, "end" : 301, "residue" : "R" }, { "start" : 263, "end" : 263, "residue" : "I" }, { "start" : 302, "end" : 302, "residue" : "S" }, { "start" : 285, "end" : 285, "residue" : "I" }, { "start" : 255, "end" : 255, "residue" : "T" }, { "start" : 266, "end" : 266, "residue" : "T" }, { "start" : 284, "end" : 284, "residue" : "M" }, { "start" : 292, "end" : 292, "residue" : "N" }, { "start" : 256, "end" : 256, "residue" : "T" }, { "start" : 283, "end" : 283, "residue" : "V" }, { "start" : 288, "end" : 288, "residue" : "T" }, { "start" : 299, "end" : 299, "residue" : "G" }, { "start" : 335, "end" : 335, "residue" : "N" }, { "start" : 273, "end" : 273, "residue" : "W" }, { "start" : 280, "end" : 280, "residue" : "P" }, { "start" : 252, "end" : 252, "residue" : "F" }, { "start" : 287, "end" : 287, "residue" : "V" }, { "start" : 310, "end" : 310, "residue" : "L" }, { "start" : 275, "end" : 275, "residue" : "E" } ] } ], "evalue" : 1.47954E-31, "score" : 115.242, "location-fragments" : [ { "start" : 252, "end" : 341, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd19049" }, { "signature" : { "accession" : "PF02931", "name" : "Neur_chan_LBD", "description" : "Neurotransmitter-gated ion-channel ligand binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006202", "name" : "Neur_chan_lig-bd", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 223, "hmmStart" : 3, "hmmEnd" : 181, "hmmLength" : 217, "hmmBounds" : "INCOMPLETE", "evalue" : 2.9E-31, "score" : 108.6, "envelopeStart" : 42, "envelopeEnd" : 250, "postProcessed" : true, "location-fragments" : [ { "start" : 44, "end" : 223, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-31, "score" : 109.1, "model-ac" : "PF02931" }, { "signature" : { "accession" : "G3DSA:2.70.170.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036734", "name" : "Neur_chan_lig-bd_sf", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 247, "hmmStart" : 9, "hmmEnd" : 218, "hmmLength" : 219, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.2E-43, "score" : 150.9, "envelopeStart" : 37, "envelopeEnd" : 249, "postProcessed" : true, "location-fragments" : [ { "start" : 37, "end" : 247, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-44, "score" : 151.3, "model-ac" : "5cfbA01" }, { "signature" : { "accession" : "PTHR18945", "name" : "NEUROTRANSMITTER GATED ION CHANNEL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 68, "end" : 349, "hmmStart" : 108, "hmmEnd" : 389, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 63, "envelopeEnd" : 361, "location-fragments" : [ { "start" : 68, "end" : 349, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-162, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 544.6, "model-ac" : "PTHR18945" }, { "signature" : { "accession" : "PTHR18945", "name" : "NEUROTRANSMITTER GATED ION CHANNEL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 358, "end" : 427, "hmmStart" : 417, "hmmEnd" : 494, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 346, "envelopeEnd" : 433, "location-fragments" : [ { "start" : 358, "end" : 427, "dc-status" : "CONTINUOUS" } ] }, { "start" : 23, "end" : 63, "hmmStart" : 38, "hmmEnd" : 78, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 67, "location-fragments" : [ { "start" : 23, "end" : 63, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-162, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 544.6, "model-ac" : "PTHR18945" }, { "signature" : { "accession" : "PTHR18945:SF819", "name" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 68, "end" : 349, "hmmStart" : 108, "hmmEnd" : 389, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 63, "envelopeEnd" : 361, "location-fragments" : [ { "start" : 68, "end" : 349, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-162, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 544.6, "model-ac" : "PTHR18945:SF819" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 444, "end" : 484, "location-fragments" : [ { "start" : 444, "end" : 484, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 453, "end" : 484, "location-fragments" : [ { "start" : 453, "end" : 484, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PR00253", "name" : "GABAARECEPTR", "description" : "Gamma-aminobutyric acid A (GABAA) receptor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR006028", "name" : "GABAA/Glycine_rcpt", "description" : "Gamma-aminobutyric acid A receptor/Glycine receptor alpha", "type" : "FAMILY", "goXRefs" : [ { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 253, "end" : 273, "pvalue" : 1.01E-5, "score" : 29.84, "motifNumber" : 1, "location-fragments" : [ { "start" : 253, "end" : 273, "dc-status" : "CONTINUOUS" } ] }, { "start" : 409, "end" : 429, "pvalue" : 2.78E-6, "score" : 34.22, "motifNumber" : 4, "location-fragments" : [ { "start" : 409, "end" : 429, "dc-status" : "CONTINUOUS" } ] }, { "start" : 279, "end" : 300, "pvalue" : 5.65E-10, "score" : 43.64, "motifNumber" : 2, "location-fragments" : [ { "start" : 279, "end" : 300, "dc-status" : "CONTINUOUS" } ] }, { "start" : 313, "end" : 334, "pvalue" : 1.31E-8, "score" : 35.36, "motifNumber" : 3, "location-fragments" : [ { "start" : 313, "end" : 334, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-22, "graphscan" : "iIII", "model-ac" : "PR00253" }, { "signature" : { "accession" : "cd18987", "name" : "LGIC_ECD_anion", "description" : "LGIC_ECD_anion", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 67, "end" : 249, "sites" : [ { "description" : "pentamer interface", "numLocations" : 30, "siteLocations" : [ { "start" : 160, "end" : 160, "residue" : "R" }, { "start" : 249, "end" : 249, "residue" : "D" }, { "start" : 148, "end" : 148, "residue" : "R" }, { "start" : 134, "end" : 134, "residue" : "G" }, { "start" : 136, "end" : 136, "residue" : "F" }, { "start" : 93, "end" : 93, "residue" : "L" }, { "start" : 126, "end" : 126, "residue" : "P" }, { "start" : 144, "end" : 144, "residue" : "H" }, { "start" : 131, "end" : 131, "residue" : "I" }, { "start" : 85, "end" : 85, "residue" : "S" }, { "start" : 188, "end" : 188, "residue" : "I" }, { "start" : 139, "end" : 139, "residue" : "P" }, { "start" : 158, "end" : 158, "residue" : "L" }, { "start" : 79, "end" : 79, "residue" : "A" }, { "start" : 130, "end" : 130, "residue" : "F" }, { "start" : 77, "end" : 77, "residue" : "S" }, { "start" : 128, "end" : 128, "residue" : "T" }, { "start" : 96, "end" : 96, "residue" : "Q" }, { "start" : 145, "end" : 145, "residue" : "F" }, { "start" : 115, "end" : 115, "residue" : "N" }, { "start" : 117, "end" : 117, "residue" : "I" }, { "start" : 86, "end" : 86, "residue" : "L" }, { "start" : 138, "end" : 138, "residue" : "D" }, { "start" : 95, "end" : 95, "residue" : "Q" }, { "start" : 127, "end" : 127, "residue" : "D" }, { "start" : 118, "end" : 118, "residue" : "H" }, { "start" : 159, "end" : 159, "residue" : "M" }, { "start" : 80, "end" : 80, "residue" : "S" }, { "start" : 129, "end" : 129, "residue" : "Y" }, { "start" : 146, "end" : 146, "residue" : "A" } ] } ], "evalue" : 9.95198E-48, "score" : 160.922, "location-fragments" : [ { "start" : 67, "end" : 249, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18987" } ], "xref" : [ { "name" : "XP_018910326.1 PREDICTED: glutamate-gated chloride channel isoform X6 [Bemisia tabaci]", "id" : "XP_018910326.1" } ] },{ "sequence" : "MESIISSAKYLIILIGILLRWCTSLHPHSGQNKPPLFGDYEAQRHWMEITTNLPVGEWYHNTTRNDLLYWGLDYPPLTAYHMWLCGVISSIFYPQSVELFSSRGYESYGHKIFMRSTVLISDLLIFFPAMYYYFLVINSSKNNVRGHNQSLLGILIALTFPGLIIVDYGHFQYNCVSLGLMTAAVAAVFKGSYKFACVLFALALNYKQMELYHALPFFFYLLGLIFKKYQKTRSIFGVALSFMTFAAMVLSTFLIVWFPFIFDASQVSQILHRVFPIYRGVFEDKVANFWCFFNVFYKLRAHCSNETIAQICLVTTAAAVLPSCFNLFIKPTLHKFKLSLIIVSLGFFLFSYHVHEKSILLVSVPVILHFLKDPFPCFWFLTVSTLSLSHLVVKDNLIIAFVALTGLFILISLSSMRKFSSINLASKSSSKSSGFLRGSIKKTHLFFLSVVGYFYLFVGLVSIEPPQRYPDIFPLLLAVYSFVHFASFFVYFYSQQFSTAEAKKEQ", "md5" : "7e63725a2e834329b4455b325c611738", "matches" : [ { "signature" : { "accession" : "PF03155", "name" : "Alg6_Alg8", "description" : "ALG6, ALG8 glycosyltransferase family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004856", "name" : "Glyco_trans_ALG6/ALG8", "description" : "Glycosyl transferase, ALG6/ALG8", "type" : "FAMILY", "goXRefs" : [ { "name" : "endoplasmic reticulum membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005789" }, { "name" : "transferase activity, transferring hexosyl groups", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016758" } ], "pathwayXRefs" : [ { "name" : "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein", "databaseName" : "Reactome", "id" : "R-HSA-446193" } ] } }, "locations" : [ { "start" : 17, "end" : 491, "hmmStart" : 2, "hmmEnd" : 484, "hmmLength" : 484, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 8.1E-134, "score" : 447.2, "envelopeStart" : 12, "envelopeEnd" : 491, "postProcessed" : true, "location-fragments" : [ { "start" : 17, "end" : 491, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-134, "score" : 447.6, "model-ac" : "PF03155" }, { "signature" : { "accession" : "PTHR12413:SF1", "name" : "DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR039488", "name" : "ALG6", "description" : "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "endoplasmic reticulum", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005783" }, { "name" : "dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0042281" }, { "name" : "dolichol-linked oligosaccharide biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006488" } ], "pathwayXRefs" : [ { "name" : "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein", "databaseName" : "Reactome", "id" : "R-HSA-446193" }, { "name" : "Defective ALG6 causes ALG6-CDG (CDG-1c)", "databaseName" : "Reactome", "id" : "R-HSA-4724289" }, { "name" : "N-Glycan biosynthesis", "databaseName" : "KEGG", "id" : "00510+2.4.1.267" } ] } }, "locations" : [ { "start" : 7, "end" : 502, "hmmStart" : 44, "hmmEnd" : 516, "hmmLength" : 526, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 506, "location-fragments" : [ { "start" : 7, "end" : 502, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-169, "familyName" : "DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE", "score" : 567.3, "model-ac" : "PTHR12413:SF1" }, { "signature" : { "accession" : "PTHR12413", "name" : "DOLICHYL GLYCOSYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR004856", "name" : "Glyco_trans_ALG6/ALG8", "description" : "Glycosyl transferase, ALG6/ALG8", "type" : "FAMILY", "goXRefs" : [ { "name" : "endoplasmic reticulum membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005789" }, { "name" : "transferase activity, transferring hexosyl groups", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016758" } ], "pathwayXRefs" : [ { "name" : "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein", "databaseName" : "Reactome", "id" : "R-HSA-446193" } ] } }, "locations" : [ { "start" : 7, "end" : 502, "hmmStart" : 44, "hmmEnd" : 516, "hmmLength" : 526, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 506, "location-fragments" : [ { "start" : 7, "end" : 502, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-169, "familyName" : "DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE", "score" : 567.3, "model-ac" : "PTHR12413" } ], "xref" : [ { "name" : "XP_018909955.1 PREDICTED: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909955.1" }, { "name" : "XP_018909956.1 PREDICTED: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909956.1" } ] },{ "sequence" : "MNNDGGGDALRKAANLGSVDLDLSEVDDVSAIYDYFNSVLKEKPKSLDIGSVSFDETTPDSSTATALHGKGSVSDCFYHIHKHGSQLGVRLLLPALNRVLCSDRVSQMTKTYNDVEAVTRLLEEKEKDIELTARIGKELLAHNQKLESTVAALEVEIKAANEKITQLTYDLHRKTELINVLTNDDSCSEASTPTGGVSLEFMQRRIGLLENENKILRDETSQLASQTDEIEAQEAKLYAELSEQLTAARVDVSCLTEEADRCREEARTAQNLASTLQEKLTVLEQKYNDLTMSNEDLSNILGFAKQTQEELTTELAELKERYAEVLGFLHDTQEALKQLQKKNQPTAKGGLLYASLQPQTYQSDSLAMELESSLFSELSLDSGISTERGLPHYKKVFDTVRCASRGSTISSGRSSDCSPYPDPLMKPSLYKPMSSDLLMTSSSQPRMSSHFSNSGSRSHRLSSITLDSAGLTDSDSSIDDFYNYPSSAAGVPGIPGSEDLAAALNKLTPGEVAARRRQLSSGVFSSHVFEPSETPRTPDSIMSTGSSGAFPFGFGMSMSTPWRLPEKLQIVKPMEGSQTLQQWSQLATPSMGGLLDEKPGIKIRGGKDLEALGLHVFTLDDVEEDDEVIHPGKSFQNSGTIYTYTNSTVMHPDDNTSVSASIAGSRMSTAANSRASSVAPTPLSRSRRNSCSTFSTGLGLAKLLNERGIQAATPSTFVTPRFSPTATPCNSPTRSRSPSPTFSPFTLPSYLMSSGAKLLRRTLTGSSSHRSRSTSRHRDSTPDKKPLGEIKLVETIERIGVNTLMSTTASDTNISDICSQLSKPSTIDATSSCLGIPGKPGSGILESRLKSLPNNARRRPTSGKQRQDLGVVLGSVSSLQKNDAANPPTTAAQSTSSPALGTLNKVLFGRKGGLL", "md5" : "80085a86f89b343a806977f35274a191", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 199, "end" : 236, "location-fragments" : [ { "start" : 199, "end" : 236, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF04849", "name" : "HAP1_N", "description" : "HAP1 N-terminal conserved region", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006933", "name" : "HAP1_N", "description" : "HAP1, N-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 99, "end" : 342, "hmmStart" : 52, "hmmEnd" : 309, "hmmLength" : 309, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 9.1E-67, "score" : 225.5, "envelopeStart" : 80, "envelopeEnd" : 342, "postProcessed" : true, "location-fragments" : [ { "start" : 99, "end" : 342, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-67, "score" : 226.2, "model-ac" : "PF04849" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 143, "end" : 170, "location-fragments" : [ { "start" : 143, "end" : 170, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 762, "end" : 789, "location-fragments" : [ { "start" : 762, "end" : 789, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR15751", "name" : "HUNTINGTIN ASSOCIATED PROTEIN 1/LATERAL SCLEROSIS-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 86, "end" : 812, "hmmStart" : 22, "hmmEnd" : 686, "hmmLength" : 689, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 74, "envelopeEnd" : 815, "location-fragments" : [ { "start" : 86, "end" : 812, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-163, "familyName" : "HUNTINGTIN ASSOCIATED PROTEIN 1/LATERAL SCLEROSIS-RELATED", "score" : 546.1, "model-ac" : "PTHR15751" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 238, "end" : 293, "location-fragments" : [ { "start" : 238, "end" : 293, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 301, "end" : 321, "location-fragments" : [ { "start" : 301, "end" : 321, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 844, "end" : 868, "location-fragments" : [ { "start" : 844, "end" : 868, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 878, "end" : 897, "location-fragments" : [ { "start" : 878, "end" : 897, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 723, "end" : 742, "location-fragments" : [ { "start" : 723, "end" : 742, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF12448", "name" : "Milton", "description" : "Kinesin associated protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022154", "name" : "TRAK1/2_C", "description" : "Trafficking kinesin-binding protein, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 435, "end" : 577, "hmmStart" : 20, "hmmEnd" : 175, "hmmLength" : 175, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.5E-23, "score" : 81.9, "envelopeStart" : 412, "envelopeEnd" : 577, "postProcessed" : true, "location-fragments" : [ { "start" : 435, "end" : 577, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-23, "score" : 81.9, "model-ac" : "PF12448" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 435, "end" : 455, "location-fragments" : [ { "start" : 435, "end" : 455, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 772, "end" : 789, "location-fragments" : [ { "start" : 772, "end" : 789, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910242.1 PREDICTED: trafficking kinesin-binding protein milt isoform X2 [Bemisia tabaci]", "id" : "XP_018910242.1" }, { "name" : "XP_018910243.1 PREDICTED: trafficking kinesin-binding protein milt isoform X2 [Bemisia tabaci]", "id" : "XP_018910243.1" }, { "name" : "XP_018910246.1 PREDICTED: trafficking kinesin-binding protein milt isoform X2 [Bemisia tabaci]", "id" : "XP_018910246.1" }, { "name" : "XP_018910245.1 PREDICTED: trafficking kinesin-binding protein milt isoform X2 [Bemisia tabaci]", "id" : "XP_018910245.1" } ] },{ "sequence" : "MAKGGVALCLSAQGRRNGEALVRFVNQEHRDMALKRHKHHIANRYIEVYKAPGEDFINVAGGRTTEAETFLTQGAEVIIRMRGLPYDCTASQIISFFEAGPEDKACHVMNGEEGVLFVKKPDKKATGDAFVLFAEESDAPKALSKHRQLIGVRYIELFRSTPAEVQQVLNRSLDTKSFESKLVMPQIQPPVPLVPQFVITSGVRKDCIRLRGLPYEASVENILEFLGDFSKNIVYQGVHMVYNSQGQPSGEAFIQMDSEASAFQAAQGRHHRYMIYGKKQRYIEVFQCSSDDMNLVHSGGLQSTNASSPVTKALISPGMLSSSGSSPTPTPVHPTVFTQPPPTLQSPWDPLVNGHLLNSLQVQSAVQQNMMRQSQPDLWMMNPTLQHLAASQMNLALAKQNWVDLSGTAATPGLLPPVQSLPALPSPNVASSAPTTNIASSSIATSPSTSVVSSSAMMPTPQAAAYLPPHFPQAQPLYLYVPPRLPAAHFQPELPPPTVQSPNQQSLQSLQSAYALTPNHLVPPASQVPQLMGVKRSWDQAFPTTQNPLSPNGNAMKRQFSYPAVSNATALYSVPPPGQSISGFQHTQFFHATI", "md5" : "e9c895a60664464a083b9d2ee071a77a", "matches" : [ { "signature" : { "accession" : "PTHR13976", "name" : "HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 318, "hmmStart" : 250, "hmmEnd" : 553, "hmmLength" : 681, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 359, "location-fragments" : [ { "start" : 1, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.8E-134, "familyName" : "EPITHELIAL SPLICING REGULATORY PROTEIN 1", "score" : 450.4, "model-ac" : "PTHR13976" }, { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 77, "end" : 162, "score" : 8.621, "alignment" : "VIIRMRGLPYDCTASQIISFF-EAGPEDKACHVMNgeegvlfvkkPDKKATGDAFVLFAEESDAPKALSkhrQLIGV----RYIELFRSTP", "location-fragments" : [ { "start" : 77, "end" : 162, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" }, { "signature" : { "accession" : "PTHR13976:SF37", "name" : "EPITHELIAL SPLICING REGULATORY PROTEIN 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 318, "hmmStart" : 250, "hmmEnd" : 553, "hmmLength" : 681, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 359, "location-fragments" : [ { "start" : 1, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.8E-134, "familyName" : "EPITHELIAL SPLICING REGULATORY PROTEIN 1", "score" : 450.4, "model-ac" : "PTHR13976:SF37" }, { "signature" : { "accession" : "SSF54928", "name" : "RNA-binding domain, RBD", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035979", "name" : "RBD_domain_sf", "description" : "RNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 79, "end" : 274, "hmmLength" : 183, "location-fragments" : [ { "start" : 203, "end" : 274, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 79, "end" : 172, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.3E-16, "model-ac" : "0049769" }, { "signature" : { "accession" : "cd12743", "name" : "RRM3_Fusilli", "description" : "RRM3_Fusilli", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 205, "end" : 289, "sites" : [ ], "evalue" : 6.6009E-53, "score" : 173.538, "location-fragments" : [ { "start" : 205, "end" : 289, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12743" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 58, "end" : 180, "hmmStart" : 8, "hmmEnd" : 114, "hmmLength" : 123, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.4E-29, "score" : 103.0, "envelopeStart" : 57, "envelopeEnd" : 180, "postProcessed" : true, "location-fragments" : [ { "start" : 58, "end" : 180, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-67, "score" : 224.8, "model-ac" : "2dhaA00" }, { "signature" : { "accession" : "SM00360", "name" : "rrm1_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 207, "end" : 286, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 0.037, "score" : 19.4, "location-fragments" : [ { "start" : 207, "end" : 286, "dc-status" : "CONTINUOUS" } ] }, { "start" : 78, "end" : 158, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 0.0032, "score" : 26.7, "location-fragments" : [ { "start" : 78, "end" : 158, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-9, "score" : 46.1, "model-ac" : "SM00360" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 321, "end" : 340, "location-fragments" : [ { "start" : 321, "end" : 340, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 200, "end" : 300, "hmmStart" : 6, "hmmEnd" : 94, "hmmLength" : 98, "hmmBounds" : "COMPLETE", "evalue" : 3.6E-26, "score" : 92.9, "envelopeStart" : 200, "envelopeEnd" : 300, "postProcessed" : true, "location-fragments" : [ { "start" : 200, "end" : 300, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-66, "score" : 219.9, "model-ac" : "2rvjA01" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 57, "hmmStart" : 42, "hmmEnd" : 93, "hmmLength" : 98, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-10, "score" : 41.9, "envelopeStart" : 1, "envelopeEnd" : 57, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 57, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-64, "score" : 214.2, "model-ac" : "4qu6A01" }, { "signature" : { "accession" : "SSF54928", "name" : "RNA-binding domain, RBD", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035979", "name" : "RBD_domain_sf", "description" : "RNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 61, "hmmLength" : 102, "location-fragments" : [ { "start" : 6, "end" : 61, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.02E-8, "model-ac" : "0050478" } ], "xref" : [ { "name" : "XP_018910050.1 PREDICTED: RNA-binding protein fusilli isoform X3 [Bemisia tabaci]", "id" : "XP_018910050.1" } ] },{ "sequence" : "MESVGGTESEAPSCKIEHLENDSVVQEVLQNGTDLRQYSRQVEKELKEVENKSIQDYIKESQNIVSLHNQIAACDDILERMESMLQSFQSDLGSISNEILSLQQKSCTMSQHLHNRQAIRGQLNQFIEEMVVSDSLISIVNDTPVTDKEFLAQLKILNHKLSFVRDQSTKEVRACQDVKDVLEKLKIKAVIKIRAYLLEQISKFRKPMTNYQIPQNAILKFKFFYEFVLTHERAVAMEVCTEYVNTMSKVYYSYFNSYSSELMKLQYDECATKHDLMATEDSAKSALFSKNSTYKQKSTIFSIGNRGEVLTSQLEAPIIVPHSAHKNDARYPFEAIFRSSQYALVDNACREYLFLGEFFMLKPSSALNIFSQVMDKTLNLLFKNLETYVDHCYDTIALFLCAHLAMRYQLLCHKRAVPALDQYWDLVQACIWPRFEFVFQLNIKSIKNCDPWKFNKEMKPHYIARRYAEYSSALIEISEEFPHELVTKLLAQLLEETHCFLLRMAAIFTTRKEQLIFLINNYDLIITTLMERTRENSKEVDNFRANLHARNMEFAEEILSPHFGGMIQYVKEEEMSGDKKQSEEMKKLENKQLAIVQPFVTSWKKSLDSIRNEVLSSFPNLVTGANLLQLTLTQFVEYYHRFLKLISLNARNQIPNIHYMMVEIKKYKTNFN", "md5" : "f3a61de144642084bc6b470123668de6", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 55, "location-fragments" : [ { "start" : 35, "end" : 55, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF04129", "name" : "Vps52", "description" : "Vps52 / Sac2 family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR007258", "name" : "Vps52", "description" : "Vps52", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Retrograde transport at the Trans-Golgi-Network", "databaseName" : "Reactome", "id" : "R-HSA-6811440" } ] } }, "locations" : [ { "start" : 49, "end" : 554, "hmmStart" : 1, "hmmEnd" : 507, "hmmLength" : 508, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.0E-190, "score" : 633.9, "envelopeStart" : 49, "envelopeEnd" : 555, "postProcessed" : true, "location-fragments" : [ { "start" : 49, "end" : 554, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-190, "score" : 634.4, "model-ac" : "PF04129" }, { "signature" : { "accession" : "PTHR14190:SF7", "name" : "VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 668, "hmmStart" : 34, "hmmEnd" : 692, "hmmLength" : 693, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 6, "envelopeEnd" : 670, "location-fragments" : [ { "start" : 16, "end" : 668, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-221, "familyName" : "VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG", "score" : 740.2, "model-ac" : "PTHR14190:SF7" }, { "signature" : { "accession" : "PTHR14190", "name" : "SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR007258", "name" : "Vps52", "description" : "Vps52", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Retrograde transport at the Trans-Golgi-Network", "databaseName" : "Reactome", "id" : "R-HSA-6811440" } ] } }, "locations" : [ { "start" : 16, "end" : 668, "hmmStart" : 34, "hmmEnd" : 692, "hmmLength" : 693, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 6, "envelopeEnd" : 670, "location-fragments" : [ { "start" : 16, "end" : 668, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-221, "familyName" : "VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG", "score" : 740.2, "model-ac" : "PTHR14190" } ], "xref" : [ { "name" : "XP_018910347.1 PREDICTED: vacuolar protein sorting-associated protein 52 homolog [Bemisia tabaci]", "id" : "XP_018910347.1" }, { "name" : "XP_018910345.1 PREDICTED: vacuolar protein sorting-associated protein 52 homolog [Bemisia tabaci]", "id" : "XP_018910345.1" }, { "name" : "XP_018910346.1 PREDICTED: vacuolar protein sorting-associated protein 52 homolog [Bemisia tabaci]", "id" : "XP_018910346.1" } ] },{ "sequence" : "MEEILGLINKEDLIRRNLIYFFLWVKKPMTTFFLREQIIEAARVCVITNSKPDLYKVFYNQASSDGLSNLKLVNWWSLEKGLFRQPLLPDPKQIYKNFHRREFEVPVLHKPPWNFVSYTNDSIRVIGGRDDKLISLLASKFKFRYTYIDPPERIQGAGVNGTMTGVLGMILRREVQLFAGDLGLTYERNQAVEFTFPTLADSEVFLTHSPGRLNEALALVRPFQWQVWLLVVLTVVASGPLLFIIIETPTCWQKKSRSMKPRNHWKVFLNCVWVSFTILLQQSIRLPSSSCRYRLVMSIFILSVVYVIGDMYSANLTSILAHPSKEQPISTLDQLADAMLFKDYQLLVEKQSSSHALLENGTGVYSWMWKKMKKQPLNLIDNIEEGMKYVKERRNYALLGGRETFTFDTRRFGTQHFHISEKLNTKYSAIAVQLGCPFLELFNEQLMFLYEAGILNKITEEEYQKLGELKVDEEVSEGGSANTGTAKQKDDEESTAMTMTSLQGSFYVLIVGHLISTVVLLIEKLYHRYNSILIGYSRKIAALIRKKQPINKAEMLERHYRYLN", "md5" : "3e68ab3f344a0dc9a7665ad0ec4d4e2e", "matches" : [ { "signature" : { "accession" : "G3DSA:3.40.190.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 202, "end" : 428, "hmmStart" : 11, "hmmEnd" : 355, "hmmLength" : 355, "hmmBounds" : "INCOMPLETE", "evalue" : 5.8E-61, "score" : 208.3, "envelopeStart" : 128, "envelopeEnd" : 523, "postProcessed" : true, "location-fragments" : [ { "start" : 202, "end" : 211, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 327, "end" : 428, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 4.4E-61, "score" : 208.7, "model-ac" : "3kg2B04" }, { "signature" : { "accession" : "PF10613", "name" : "Lig_chan-Glu_bd", "description" : "Ligated ion channel L-glutamate- and glycine-binding site", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR019594", "name" : "Glu/Gly-bd", "description" : "Ionotropic glutamate receptor, L-glutamate and glycine-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "ionotropic glutamate receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004970" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 126, "end" : 202, "hmmStart" : 29, "hmmEnd" : 107, "hmmLength" : 116, "hmmBounds" : "INCOMPLETE", "evalue" : 2.7E-8, "score" : 34.0, "envelopeStart" : 101, "envelopeEnd" : 210, "postProcessed" : true, "location-fragments" : [ { "start" : 126, "end" : 202, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-8, "score" : 35.0, "model-ac" : "PF10613" }, { "signature" : { "accession" : "PTHR42643", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 109, "end" : 531, "hmmStart" : 56, "hmmEnd" : 456, "hmmLength" : 482, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 551, "location-fragments" : [ { "start" : 109, "end" : 531, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-57, "familyName" : "IONOTROPIC RECEPTOR 40A-RELATED", "score" : 195.9, "model-ac" : "PTHR42643" }, { "signature" : { "accession" : "PTHR42643:SF13", "name" : "IONOTROPIC RECEPTOR 40A-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 109, "end" : 531, "hmmStart" : 56, "hmmEnd" : 456, "hmmLength" : 482, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 551, "location-fragments" : [ { "start" : 109, "end" : 531, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-57, "familyName" : "IONOTROPIC RECEPTOR 40A-RELATED", "score" : 195.9, "model-ac" : "PTHR42643:SF13" }, { "signature" : { "accession" : "G3DSA:3.40.190.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 133, "end" : 474, "hmmStart" : 11, "hmmEnd" : 355, "hmmLength" : 146, "hmmBounds" : "INCOMPLETE", "evalue" : 5.8E-61, "score" : 208.3, "envelopeStart" : 128, "envelopeEnd" : 523, "postProcessed" : true, "location-fragments" : [ { "start" : 429, "end" : 474, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 133, "end" : 201, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 4.4E-61, "score" : 208.7, "model-ac" : "3kg2B03" }, { "signature" : { "accession" : "SSF53850", "name" : "Periplasmic binding protein-like II", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 100, "end" : 460, "hmmLength" : 257, "location-fragments" : [ { "start" : 325, "end" : 460, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 100, "end" : 210, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 6.62E-27, "model-ac" : "0049318" }, { "signature" : { "accession" : "G3DSA:1.10.287.70", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 212, "end" : 523, "hmmStart" : 11, "hmmEnd" : 355, "hmmLength" : 355, "hmmBounds" : "INCOMPLETE", "evalue" : 5.8E-61, "score" : 208.3, "envelopeStart" : 128, "envelopeEnd" : 523, "postProcessed" : true, "location-fragments" : [ { "start" : 212, "end" : 326, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 495, "end" : 523, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 4.4E-61, "score" : 208.7, "model-ac" : "3kg2B05" }, { "signature" : { "accession" : "PF00060", "name" : "Lig_chan", "description" : "Ligand-gated ion channel", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001320", "name" : "Iontro_rcpt", "description" : "Ionotropic glutamate receptor", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0015276" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 224, "end" : 512, "hmmStart" : 1, "hmmEnd" : 148, "hmmLength" : 149, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.1E-19, "score" : 70.7, "envelopeStart" : 224, "envelopeEnd" : 513, "postProcessed" : true, "location-fragments" : [ { "start" : 224, "end" : 512, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-20, "score" : 71.1, "model-ac" : "PF00060" } ], "xref" : [ { "name" : "XP_018909625.1 PREDICTED: glutamate receptor ionotropic, kainate 4-like [Bemisia tabaci]", "id" : "XP_018909625.1" } ] },{ "sequence" : "MCNPVEPSRSLDVPGQEVKDHFQYANAKKSAWAQILATIMQNWLLIEIGLEMVMPTVIIGSLHNNPAEPLNMNDDQASWFGSIPDFCHPIGSLTSGLLQDKFGRKGAMMLINIPIFIGWMILYFAQSIHALYAVSVIMGLCTGLAEAPLHAYIGEIGEPRMRGTLSTISTSCCTIGVCAMFLFGYLFDWRTVALVSSSCSIITFTFMTQLPESPTWLIVRGRLDEAKKSLCWLRGWVSSAEVEPEFQSLVNYAVKSADLSRENSADSSLPIKEGEPVAERGGFLKQQLKELTNKRTFRPLRLMFFVFIITNIACVSGIMPYFVNELKMLESPIDPNLALMMCSGLFFVGAMVNVVFLRRFGKRKIALFSHILTGICILSVGMYASFLQSLTQYPLRVWLPLILWFIMNFLHGFSIITLPWQLVCEVFPPLGRGTATGLAAAWTHFFMSVLTKTYLYMEAWLGFSGVMYLYGVCTMAGVIYHYFYLPETEGKTLEQIETYFTKNHDKREKFSVGKSQRQRAQSESPS", "md5" : "e9b6e132b0fa21b486fa1751923fbf92", "matches" : [ { "signature" : { "accession" : "PTHR23500", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 392, "end" : 507, "hmmStart" : 534, "hmmEnd" : 649, "hmmLength" : 950, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 385, "envelopeEnd" : 524, "location-fragments" : [ { "start" : 392, "end" : 507, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-88, "familyName" : "", "score" : 301.0, "model-ac" : "PTHR23500" }, { "signature" : { "accession" : "PS50850", "name" : "MFS", "description" : "Major facilitator superfamily (MFS) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR020846", "name" : "MFS_dom", "description" : "Major facilitator superfamily domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 35, "end" : 489, "score" : 23.351, "alignment" : "ILATIMQNWLLIEIGLEMVmptviiGSLHNNPAEPLNMNDDQASWFGSIPDFCHPIGSLTSGLLQDKFGRKGAMMLINIPIFIGWMILYFAQSIHALYAVSVIMGLCTGLAEAPLHAYIGEIGEPRMRGTLSTI----STSCCTIGVCAMFLFGYLFDWRTVALVSSSCSIITFTFM-TQLPESPTWlivrgrldeakkslcwlrgwvssaevepefqslvnyavksadlsreNSADSSLPIKEGEPVAERGGFLKQQLkeltnkRTFRPLRLMFFVFIITnIACVSGIMPYFVNELKmLESPIDPNLALMMCSGL--FFVGAMVNVVFLRRFGKRKIALFSHILTGICILSVGMYASFLQsltqyplrvWLPLILWFIMNFLHGFSIITLPWQLVCEVFPPLGRGTATGLAAAWThFFMSVLTKTYLYMEAWlGFSG--VMYLYGVCTMAGVIYHYFYLPETE", "location-fragments" : [ { "start" : 35, "end" : 489, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50850" }, { "signature" : { "accession" : "PTHR23500:SF3", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 392, "end" : 507, "hmmStart" : 534, "hmmEnd" : 649, "hmmLength" : 950, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 385, "envelopeEnd" : 524, "location-fragments" : [ { "start" : 392, "end" : 507, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-88, "familyName" : "", "score" : 301.0, "model-ac" : "PTHR23500:SF3" }, { "signature" : { "accession" : "G3DSA:1.20.1250.20", "name" : "MFS general substrate transporter like domains", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 31, "end" : 504, "hmmStart" : 50, "hmmEnd" : 466, "hmmLength" : 470, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-79, "score" : 270.3, "envelopeStart" : 31, "envelopeEnd" : 504, "postProcessed" : true, "location-fragments" : [ { "start" : 31, "end" : 504, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.9E-80, "score" : 270.7, "model-ac" : "4zw9A00" }, { "signature" : { "accession" : "PS00217", "name" : "SUGAR_TRANSPORT_2", "description" : "Sugar transport proteins signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR005829", "name" : "Sugar_transporter_CS", "description" : "Sugar transporter, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 137, "end" : 162, "level" : "STRONG", "cigarAlignment" : "1M1I3M1I2M7I1M2I1M6I1M", "alignment" : "ImGLCtGLaeaplhaYigEigeprmR", "location-fragments" : [ { "start" : 137, "end" : 162, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00217" }, { "signature" : { "accession" : "cd17358", "name" : "MFS_GLUT6_8_Class3_like", "description" : "MFS_GLUT6_8_Class3_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 495, "sites" : [ { "description" : "chemical substrate binding pocket", "numLocations" : 21, "siteLocations" : [ { "start" : 412, "end" : 412, "residue" : "G" }, { "start" : 443, "end" : 443, "residue" : "T" }, { "start" : 420, "end" : 420, "residue" : "W" }, { "start" : 177, "end" : 177, "residue" : "V" }, { "start" : 320, "end" : 320, "residue" : "P" }, { "start" : 48, "end" : 48, "residue" : "I" }, { "start" : 170, "end" : 170, "residue" : "T" }, { "start" : 416, "end" : 416, "residue" : "I" }, { "start" : 315, "end" : 315, "residue" : "V" }, { "start" : 444, "end" : 444, "residue" : "H" }, { "start" : 415, "end" : 415, "residue" : "I" }, { "start" : 174, "end" : 174, "residue" : "T" }, { "start" : 316, "end" : 316, "residue" : "S" }, { "start" : 346, "end" : 346, "residue" : "F" }, { "start" : 312, "end" : 312, "residue" : "I" }, { "start" : 319, "end" : 319, "residue" : "M" }, { "start" : 411, "end" : 411, "residue" : "H" }, { "start" : 447, "end" : 447, "residue" : "M" }, { "start" : 52, "end" : 52, "residue" : "M" }, { "start" : 173, "end" : 173, "residue" : "C" }, { "start" : 311, "end" : 311, "residue" : "N" } ] } ], "evalue" : 2.94204E-81, "score" : 258.274, "location-fragments" : [ { "start" : 35, "end" : 495, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd17358" }, { "signature" : { "accession" : "PF00083", "name" : "Sugar_tr", "description" : "Sugar (and other) transporter", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005828", "name" : "MFS_sugar_transport-like", "description" : "Major facilitator, sugar transporter-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 69, "end" : 500, "hmmStart" : 40, "hmmEnd" : 452, "hmmLength" : 452, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.0E-49, "score" : 169.7, "envelopeStart" : 30, "envelopeEnd" : 500, "postProcessed" : true, "location-fragments" : [ { "start" : 69, "end" : 500, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-50, "score" : 170.4, "model-ac" : "PF00083" }, { "signature" : { "accession" : "SSF103473", "name" : "MFS general substrate transporter", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036259", "name" : "MFS_trans_sf", "description" : "MFS transporter superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 53, "end" : 497, "hmmLength" : 447, "location-fragments" : [ { "start" : 53, "end" : 237, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 278, "end" : 497, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.57E-53, "model-ac" : "0042501" }, { "signature" : { "accession" : "PTHR23500:SF3", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 31, "end" : 385, "hmmStart" : 60, "hmmEnd" : 405, "hmmLength" : 950, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 395, "location-fragments" : [ { "start" : 31, "end" : 385, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-88, "familyName" : "", "score" : 301.0, "model-ac" : "PTHR23500:SF3" }, { "signature" : { "accession" : "PTHR23500", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 31, "end" : 385, "hmmStart" : 60, "hmmEnd" : 405, "hmmLength" : 950, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 395, "location-fragments" : [ { "start" : 31, "end" : 385, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-88, "familyName" : "", "score" : 301.0, "model-ac" : "PTHR23500" } ], "xref" : [ { "name" : "XP_018909634.1 PREDICTED: facilitated trehalose transporter Tret1-like [Bemisia tabaci]", "id" : "XP_018909634.1" } ] },{ "sequence" : "MMVEVKVWQNLEEQTTGRGVSVSGTSGSFANCGSKTFAVCSNYKAQELSAMPSDSMDDIELQNVQLQFPSARSLSREGSDVEEIKVETDRGHLLVAVQGNRSKPAIVTYHDLGLNYVSSFQAFFNYLDMRQLLNNFSVYHVNAPGQEEGAPPFPDDYEYPTMDDLAAQLNFVLTHFGLRSIIGLGVGAGGNILARFALSNPDKVEALCLINVVSTAAGWIEWGYQKLNARYLRSKGMTQGVLDYLMWHHFGRGTEERNHDLVQVYRNYFERCVNPGNLALFIDSYIRRTDLNIERDPDPNRRKEGGGSPTLSMPVMNITGSLSPHVNDTVTLNSRLDPSNSSWMKISDCGMVLEEQPNKVCEALRLFLQGLGYAVKLGRPKITNSTSAEAFIVMSVKTSRSLDSVRSAPWSIRITENPISETAAC", "md5" : "abdf205395da76a31ee5daf424430432", "matches" : [ { "signature" : { "accession" : "G3DSA:3.40.50.1820", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 74, "end" : 370, "hmmStart" : 9, "hmmEnd" : 286, "hmmLength" : 286, "hmmBounds" : "COMPLETE", "evalue" : 3.5E-93, "score" : 314.1, "envelopeStart" : 74, "envelopeEnd" : 370, "postProcessed" : true, "location-fragments" : [ { "start" : 74, "end" : 370, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-93, "score" : 314.5, "model-ac" : "2qmqA00" }, { "signature" : { "accession" : "PTHR11034:SF19", "name" : "GH09802P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 84, "end" : 382, "hmmStart" : 3, "hmmEnd" : 294, "hmmLength" : 301, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 48, "envelopeEnd" : 393, "location-fragments" : [ { "start" : 84, "end" : 382, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-128, "familyName" : "GH09802P", "score" : 429.4, "model-ac" : "PTHR11034:SF19" }, { "signature" : { "accession" : "SSF53474", "name" : "alpha/beta-Hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 81, "end" : 369, "hmmLength" : 281, "location-fragments" : [ { "start" : 81, "end" : 369, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.31E-26, "model-ac" : "0046077" }, { "signature" : { "accession" : "PTHR11034", "name" : "N-MYC DOWNSTREAM REGULATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR004142", "name" : "NDRG", "description" : "NDRG", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 84, "end" : 382, "hmmStart" : 3, "hmmEnd" : 294, "hmmLength" : 301, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 48, "envelopeEnd" : 393, "location-fragments" : [ { "start" : 84, "end" : 382, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-128, "familyName" : "GH09802P", "score" : 429.4, "model-ac" : "PTHR11034" }, { "signature" : { "accession" : "PF03096", "name" : "Ndr", "description" : "Ndr family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004142", "name" : "NDRG", "description" : "NDRG", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 85, "end" : 373, "hmmStart" : 3, "hmmEnd" : 281, "hmmLength" : 283, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-103, "score" : 345.1, "envelopeStart" : 83, "envelopeEnd" : 375, "postProcessed" : true, "location-fragments" : [ { "start" : 85, "end" : 373, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-103, "score" : 345.5, "model-ac" : "PF03096" } ], "xref" : [ { "name" : "XP_018910085.1 PREDICTED: protein NDRG3 isoform X4 [Bemisia tabaci]", "id" : "XP_018910085.1" } ] },{ "sequence" : "MATKEVLRKKLEDMIHYLTPFLPLVNSHVVNFITDNQWDNTVPENLRAEFSTKGFENITNLLWRYHDDPTCLSDDVSNSPLVQHFIEAQKMSLTSQPNLCLSLNDLQTKLASLHCKEHTNLKISRLMSEKKSYEVDVMSQVVLSMVSATDCSHIVDIGGGKAYLSSNLSLQHNLKVLSIDQCRGNTHGAAERLERLKKVWNRMKYNAENPYEGKKGKNWKSKKKIPAAESTLNFLNSEAAGNPLFKQRTEFITSTTDIRHILRDSFPGDSISGAGLVGLHTCGNLASAHLRIFVQNLNVFKFLLNIGCCYHLIQEEFSEDKFWNEIKACTEDQSEPGFPMSSFLREREFFLSRNPRMLATQSPERVLHERKLVTVPLFYRSLLQVLLTKKSNGDDFPYCVVGRLALKCTNFTEYALKAVKKIGLKATVTEDELDELYRSHYHHFDRIQMFFLIRVGLSPVLESLILLDRLLYLHEQGVEDSFIAQIFDPVKSPRCYAIISIRKDDSRDGKS", "md5" : "292011a4ac44745906cb9da4a19752fa", "matches" : [ { "signature" : { "accession" : "PTHR12496:SF0", "name" : "METHYLTRANSFERASE-LIKE PROTEIN 25", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 503, "hmmStart" : 21, "hmmEnd" : 520, "hmmLength" : 523, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 506, "location-fragments" : [ { "start" : 5, "end" : 503, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-107, "familyName" : "METHYLTRANSFERASE-LIKE PROTEIN 25", "score" : 361.9, "model-ac" : "PTHR12496:SF0" }, { "signature" : { "accession" : "PF13679", "name" : "Methyltransf_32", "description" : "Methyltransferase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR025714", "name" : "Methyltranfer_dom", "description" : "Methyltransferase domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 130, "end" : 316, "hmmStart" : 1, "hmmEnd" : 158, "hmmLength" : 158, "hmmBounds" : "COMPLETE", "evalue" : 7.0E-26, "score" : 91.1, "envelopeStart" : 130, "envelopeEnd" : 316, "postProcessed" : true, "location-fragments" : [ { "start" : 130, "end" : 316, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-26, "score" : 92.0, "model-ac" : "PF13679" }, { "signature" : { "accession" : "PTHR12496", "name" : "CGI-41 METHYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 503, "hmmStart" : 21, "hmmEnd" : 520, "hmmLength" : 523, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 506, "location-fragments" : [ { "start" : 5, "end" : 503, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-107, "familyName" : "METHYLTRANSFERASE-LIKE PROTEIN 25", "score" : 361.9, "model-ac" : "PTHR12496" } ], "xref" : [ { "name" : "XP_018910524.1 PREDICTED: methyltransferase-like protein 25 [Bemisia tabaci]", "id" : "XP_018910524.1" } ] },{ "sequence" : "MDDLPPEQISVLRKAFDAFDRERSGSIPTDMVADILRLMGQPFNKKILDELIEEVDADKSGRLEFDEFVTLAAKFIVEEDDEAMQKELREAFRLYDKEGNGYIPTSCLKEILRELDDQLTNEELDMMIDEIDSDGSGTVDFDEFMEMMTGE", "md5" : "2581525f73a2e0de94446302272a8523", "matches" : [ { "signature" : { "accession" : "PS00018", "name" : "EF_HAND_1", "description" : "EF-hand calcium-binding domain.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018247", "name" : "EF_Hand_1_Ca_BS", "description" : "EF-Hand 1, calcium-binding site", "type" : "BINDING_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 132, "end" : 144, "level" : "STRONG", "cigarAlignment" : "9M2I2M", "alignment" : "DSDGSGTVDfdEF", "location-fragments" : [ { "start" : 132, "end" : 144, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00018" }, { "signature" : { "accession" : "SSF47473", "name" : "EF-hand", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011992", "name" : "EF-hand-dom_pair", "description" : "EF-hand domain pair", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 149, "hmmLength" : 194, "location-fragments" : [ { "start" : 2, "end" : 149, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.73E-41, "model-ac" : "0037066" }, { "signature" : { "accession" : "PTHR23050", "name" : "CALCIUM BINDING PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 151, "hmmStart" : 6, "hmmEnd" : 155, "hmmLength" : 155, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 151, "location-fragments" : [ { "start" : 2, "end" : 151, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-84, "familyName" : "TROPONIN C, ISOFORM 2-RELATED", "score" : 282.4, "model-ac" : "PTHR23050" }, { "signature" : { "accession" : "G3DSA:1.10.238.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 74, "end" : 151, "hmmStart" : 42, "hmmEnd" : 115, "hmmLength" : 139, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 6.9E-25, "score" : 89.1, "envelopeStart" : 72, "envelopeEnd" : 151, "postProcessed" : true, "location-fragments" : [ { "start" : 74, "end" : 151, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1, "end" : 73, "hmmStart" : 46, "hmmEnd" : 114, "hmmLength" : 139, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.2E-19, "score" : 69.8, "envelopeStart" : 1, "envelopeEnd" : 75, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 73, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-45, "score" : 154.4, "model-ac" : "2g2bA01" }, { "signature" : { "accession" : "PS50222", "name" : "EF_HAND_2", "description" : "EF-hand calcium-binding domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002048", "name" : "EF_hand_dom", "description" : "EF-hand domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 42, "score" : 11.556, "alignment" : "EQISVLRKAFDAFDRERSGSIPTDMVADILRlMGqP", "location-fragments" : [ { "start" : 7, "end" : 42, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50222" }, { "signature" : { "accession" : "PS00018", "name" : "EF_HAND_1", "description" : "EF-hand calcium-binding domain.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018247", "name" : "EF_Hand_1_Ca_BS", "description" : "EF-Hand 1, calcium-binding site", "type" : "BINDING_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 56, "end" : 68, "level" : "STRONG", "cigarAlignment" : "9M2I2M", "alignment" : "DADKSGRLEfdEF", "location-fragments" : [ { "start" : 56, "end" : 68, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00018" }, { "signature" : { "accession" : "SM00054", "name" : "efh_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002048", "name" : "EF_hand_dom", "description" : "EF-hand domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 123, "end" : 151, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-6, "score" : 37.5, "location-fragments" : [ { "start" : 123, "end" : 151, "dc-status" : "CONTINUOUS" } ] }, { "start" : 11, "end" : 39, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 7.3, "score" : 10.8, "location-fragments" : [ { "start" : 11, "end" : 39, "dc-status" : "CONTINUOUS" } ] }, { "start" : 87, "end" : 115, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 0.0053, "score" : 26.0, "location-fragments" : [ { "start" : 87, "end" : 115, "dc-status" : "CONTINUOUS" } ] }, { "start" : 47, "end" : 75, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-4, "score" : 31.5, "location-fragments" : [ { "start" : 47, "end" : 75, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-27, "score" : 105.8, "model-ac" : "SM00054" }, { "signature" : { "accession" : "PS50222", "name" : "EF_HAND_2", "description" : "EF-hand calcium-binding domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002048", "name" : "EF_hand_dom", "description" : "EF-hand domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 83, "end" : 118, "score" : 11.166, "alignment" : "AMQKELREAFRLYDKEGNGYIPTSCLKEILReLDdQ", "location-fragments" : [ { "start" : 83, "end" : 118, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50222" }, { "signature" : { "accession" : "PTHR23050:SF244", "name" : "TROPONIN C, ISOFORM 2-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 151, "hmmStart" : 6, "hmmEnd" : 155, "hmmLength" : 155, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 151, "location-fragments" : [ { "start" : 2, "end" : 151, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-84, "familyName" : "TROPONIN C, ISOFORM 2-RELATED", "score" : 282.4, "model-ac" : "PTHR23050:SF244" }, { "signature" : { "accession" : "PF13499", "name" : "EF-hand_7", "description" : "EF-hand domain pair", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002048", "name" : "EF_hand_dom", "description" : "EF-hand domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 71, "hmmStart" : 2, "hmmEnd" : 68, "hmmLength" : 70, "hmmBounds" : "INCOMPLETE", "evalue" : 1.4E-9, "score" : 38.3, "envelopeStart" : 9, "envelopeEnd" : 73, "postProcessed" : true, "location-fragments" : [ { "start" : 10, "end" : 71, "dc-status" : "CONTINUOUS" } ] }, { "start" : 86, "end" : 148, "hmmStart" : 2, "hmmEnd" : 69, "hmmLength" : 70, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-14, "score" : 54.1, "envelopeStart" : 85, "envelopeEnd" : 149, "postProcessed" : true, "location-fragments" : [ { "start" : 86, "end" : 148, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.3E-26, "score" : 90.1, "model-ac" : "PF13499" }, { "signature" : { "accession" : "PS50222", "name" : "EF_HAND_2", "description" : "EF-hand calcium-binding domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002048", "name" : "EF_hand_dom", "description" : "EF-hand domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 119, "end" : 151, "score" : 13.928, "alignment" : "LTNEELDMMIDEIDSDGSGTVDFDEFMEMMTgE--", "location-fragments" : [ { "start" : 119, "end" : 151, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50222" }, { "signature" : { "accession" : "PS50222", "name" : "EF_HAND_2", "description" : "EF-hand calcium-binding domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002048", "name" : "EF_hand_dom", "description" : "EF-hand domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 43, "end" : 78, "score" : 11.975, "alignment" : "FNKKILDELIEEVDADKSGRLEFDEFVTLAAkFIvE", "location-fragments" : [ { "start" : 43, "end" : 78, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50222" }, { "signature" : { "accession" : "cd00051", "name" : "EFh", "description" : "EFh", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR002048", "name" : "EF_hand_dom", "description" : "EF-hand domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 87, "end" : 149, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 134, "end" : 134, "residue" : "D" }, { "start" : 107, "end" : 107, "residue" : "C" }, { "start" : 132, "end" : 132, "residue" : "D" }, { "start" : 143, "end" : 143, "residue" : "E" }, { "start" : 98, "end" : 98, "residue" : "E" }, { "start" : 96, "end" : 96, "residue" : "D" }, { "start" : 100, "end" : 100, "residue" : "N" }, { "start" : 136, "end" : 136, "residue" : "S" } ] } ], "evalue" : 8.04899E-18, "score" : 70.6545, "location-fragments" : [ { "start" : 87, "end" : 149, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00051" } ], "xref" : [ { "name" : "XP_018910308.1 PREDICTED: troponin C [Bemisia tabaci]", "id" : "XP_018910308.1" } ] },{ "sequence" : "MKSIAVFSILALAVVRAEESAGDSKSVKKNEKRSYEGFGYGYGGLGLGHSTLGGLYAGHGLVGGHGPVVGHGLYGASYGAYPTSIHTTITKQVPVPVPHPVAVPVEKHVPYPVAAPYPVEVPRPYPVAVPKPVAVPVEKPVPVPVDRPYPVAVPHPVAVPVAKPVPVPYPQPYAVPVVKPYPVAVSHPVPVPVAKPIIAHAPYHSYHNYW", "md5" : "1bb6e15f7305a34a8ef7231a1b950ce5", "matches" : [ { "signature" : { "accession" : "PTHR47771:SF3", "name" : "HDC01644", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 206, "hmmStart" : 1, "hmmEnd" : 207, "hmmLength" : 207, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 209, "location-fragments" : [ { "start" : 1, "end" : 206, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-45, "familyName" : "HDC01644", "score" : 156.7, "model-ac" : "PTHR47771:SF3" }, { "signature" : { "accession" : "PTHR47771", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 206, "hmmStart" : 1, "hmmEnd" : 207, "hmmLength" : 207, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 209, "location-fragments" : [ { "start" : 1, "end" : 206, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-45, "familyName" : "HDC01644", "score" : 156.7, "model-ac" : "PTHR47771" } ], "xref" : [ { "name" : "XP_018909845.1 PREDICTED: uncharacterized protein LOC109038997 [Bemisia tabaci]", "id" : "XP_018909845.1" } ] },{ "sequence" : "MASIVGSTLNLFTSSINSLFKNQQPWEIVAITSSTILFLSWAWQVYEIEESLFSRGKKKFFKLARKIPFVSKKLETELDKIRELFHKDTVERLQETSYCVSLPKEAKTETEIMDSLQKFLNLGEFEWEKGFISGAIYCENKALKNLVGEVYKLTSYTNPLHPDVFPGICFIEADIIRMAANLFHGTHDTCGSVTSGGTESIVMACKAYRDYAEATKGITNPVILLPTTAHPAFDKGCAYFKVYAKHVKVDPVTFKVDIQAMEKAISKNTILLVGSAPNFPYGTMDDIVAIAALGRKYNIPVHVDSCLGGFLTAFMPHAGFEVEHCDFSVPGVTSISADTHKYGFTPKGSSVILYAHPKYRHHQYFVVADWPGGTYGSPSMNGSRTGGLIAAAWATLLYFGFDGYVKATKEIISTTRYIEKRIREECDDVFIFGTPATSVIAVGSNKFHIYRLVEGLKKHGWNLNTLQFPSGFHLCVTHLHTQEGVADKFIDNMKEELVKIKENPNVKLEGMMAMYGVSHTIPDRTIVEDFARIYLDYLTFLPPEETDKEKKPSNGVLKAA", "md5" : "2efc2814155563aeb110a5005412aff0", "matches" : [ { "signature" : { "accession" : "PF00282", "name" : "Pyridoxal_deC", "description" : "Pyridoxal-dependent decarboxylase conserved domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002129", "name" : "PyrdxlP-dep_de-COase", "description" : "Pyridoxal phosphate-dependent decarboxylase", "type" : "FAMILY", "goXRefs" : [ { "name" : "carboxy-lyase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016831" }, { "name" : "pyridoxal phosphate binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030170" }, { "name" : "carboxylic acid metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0019752" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 101, "end" : 427, "hmmStart" : 11, "hmmEnd" : 358, "hmmLength" : 375, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-16, "score" : 60.0, "envelopeStart" : 93, "envelopeEnd" : 442, "postProcessed" : true, "location-fragments" : [ { "start" : 101, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-16, "score" : 60.6, "model-ac" : "PF00282" }, { "signature" : { "accession" : "PTHR42735", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 539, "hmmStart" : 16, "hmmEnd" : 543, "hmmLength" : 546, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 541, "location-fragments" : [ { "start" : 12, "end" : 539, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-202, "familyName" : "SPHINGOSINE-1-PHOSPHATE LYASE 1", "score" : 674.3, "model-ac" : "PTHR42735" }, { "signature" : { "accession" : "PTHR42735:SF6", "name" : "SPHINGOSINE-1-PHOSPHATE LYASE 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 539, "hmmStart" : 16, "hmmEnd" : 543, "hmmLength" : 546, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 541, "location-fragments" : [ { "start" : 12, "end" : 539, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-202, "familyName" : "SPHINGOSINE-1-PHOSPHATE LYASE 1", "score" : 674.3, "model-ac" : "PTHR42735:SF6" }, { "signature" : { "accession" : "SSF53383", "name" : "PLP-dependent transferases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR015424", "name" : "PyrdxlP-dep_Trfase", "description" : "Pyridoxal phosphate-dependent transferase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 92, "end" : 497, "hmmLength" : 450, "location-fragments" : [ { "start" : 92, "end" : 497, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.01E-105, "model-ac" : "0042383" }, { "signature" : { "accession" : "G3DSA:3.40.640.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015421", "name" : "PyrdxlP-dep_Trfase_major", "description" : "Pyridoxal phosphate-dependent transferase, major domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 172, "end" : 400, "hmmStart" : 1, "hmmEnd" : 317, "hmmLength" : 320, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.6E-117, "score" : 393.0, "envelopeStart" : 172, "envelopeEnd" : 498, "postProcessed" : true, "location-fragments" : [ { "start" : 172, "end" : 400, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-117, "score" : 394.3, "model-ac" : "4w8iA02" }, { "signature" : { "accession" : "G3DSA:3.90.1150.10", "name" : "Aspartate Aminotransferase", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015422", "name" : "PyrdxlP-dep_Trfase_dom1", "description" : "Pyridoxal phosphate-dependent transferase domain 1", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 401, "end" : 495, "hmmStart" : 1, "hmmEnd" : 317, "hmmLength" : 123, "hmmBounds" : "INCOMPLETE", "evalue" : 3.6E-117, "score" : 393.0, "envelopeStart" : 172, "envelopeEnd" : 498, "postProcessed" : true, "location-fragments" : [ { "start" : 401, "end" : 495, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-117, "score" : 394.3, "model-ac" : "4w8iA01" } ], "xref" : [ { "name" : "XP_018910056.1 PREDICTED: sphingosine-1-phosphate lyase [Bemisia tabaci]", "id" : "XP_018910056.1" } ] },{ "sequence" : "MDQELAKSEKRLQLREVNPYLICVLCGGYFVDAASIVECLHTFCWTCIVKYLEKNKFCPICDVQAYKTKPHLSIRPDYTIQRLTYKMVPGLFAKEMKRRKEFYLSSDPPPTAVNLPPSAFYSPDDNISLSLEYYEAGMNNNDEKCRQAGDEHDSLKMKLLPHKRYLQCPAAVTINHLKKFVRMKYGLAAEQMVDIIYQEECLPEDFSLMDVAYTFMWDRTTPMRFSYRILERAAVPAESNSDINGAHGYSASKNDFKRNSWPRNGPNSSSESGTTNTTNGRQLRGNVFSKRKSDSGNESNEASTKDEADELDDLSLVKRLRMNARQTRSSNKKASPRRRSRSTSTKRKKQKKTAIESDALSGYSSATSPDYPSSSVPSNVDEMDSFDDDAKYEDDIEEITDDFDDDDDEGRLWISPTEDETKDKDSEVTSQESSGDIDMDDDEKMVIDPSEEIDDRSEVKVKKKSKKGKHHHHHHHHHRHTKKTPPATILKSESNDIMKLKVKLNPIIACEKYDKPSKSSSKSRTVGEVVPMYSSNSRLTADSANDSKSNAFNNNAGITNVSNKLSNKTNERRKSTDRSCSKISSSSDISSSTSRLKSGSCNSSKDYDNIAHNSFADDSSQGSRVSEENAELKRAMDVINEDLECQEVASKVADAKVPKVPEKSYRPPSLPQSLPNSTSFTRKSSPTPLIFTTCDSNSSRSKSPLLHPPSSITVSKITAAEKRKLDEDKLLNNNQDPKAADNLRPSLEIMLVNGPKMQSFFNVDSKKDASRLKGNNGQTVKSSIPASHCTSVSTSVSSSSSASLSTSPLVRLQKMSINLPSVTVTHSTSTSKTTNTSKTVVQNKNEPCIQAGSIEISLQKENTAPTRIENRDMKKTDGQKKGTVGSTGALDLSPTSQLTRPSVSGASSGTVHTSSSTNHSNITLKRPKSVPPVCIKPQVNKIPPQLNTGKVGSTNGPKSIPVSMQNLTVLSNAAAHLAAKSQQDQRNTIQINGNSSPSIKSAQNPQILPASPSPKNNHSVSNLNNCLQQNMSLKIPSLQQRPIKNPSFKQDNSPVRSKPMNMPKLNEIDRKQFIRPAPHGNNSSGINTTKPGQNQFVRHITDPSVMIYARQQNASVVSGNHSSSGNSMSKKFVSGNNGRLSSPPGVIPIASMFRQGGIAREIEKVSAGLQMKTTVNKELTSVK", "md5" : "0ae6715b88ec6e3d0ed0d9fc63a12917", "matches" : [ { "signature" : { "accession" : "PS00518", "name" : "ZF_RING_1", "description" : "Zinc finger RING-type signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017907", "name" : "Znf_RING_CS", "description" : "Zinc finger, RING-type, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 39, "end" : 48, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I2M2I2M", "alignment" : "ClHtFCwtCI", "location-fragments" : [ { "start" : 39, "end" : 48, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00518" }, { "signature" : { "accession" : "G3DSA:3.10.20.90", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 118, "end" : 235, "hmmStart" : 4, "hmmEnd" : 109, "hmmLength" : 115, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-38, "score" : 132.4, "envelopeStart" : 118, "envelopeEnd" : 235, "postProcessed" : true, "location-fragments" : [ { "start" : 118, "end" : 235, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-39, "score" : 134.2, "model-ac" : "5fr6A00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 880, "end" : 924, "location-fragments" : [ { "start" : 880, "end" : 924, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR10825", "name" : "RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 361, "hmmStart" : 5, "hmmEnd" : 362, "hmmLength" : 1189, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 385, "location-fragments" : [ { "start" : 10, "end" : 361, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-96, "familyName" : "POLYCOMB GROUP PROTEIN PSC-RELATED", "score" : 326.2, "model-ac" : "PTHR10825" }, { "signature" : { "accession" : "PF16207", "name" : "RAWUL", "description" : "RAWUL domain RING finger- and WD40-associated ubiquitin-like", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR032443", "name" : "RAWUL", "description" : "RAWUL domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 164, "end" : 228, "hmmStart" : 1, "hmmEnd" : 74, "hmmLength" : 74, "hmmBounds" : "COMPLETE", "evalue" : 8.8E-16, "score" : 58.3, "envelopeStart" : 164, "envelopeEnd" : 228, "postProcessed" : true, "location-fragments" : [ { "start" : 164, "end" : 228, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.7E-16, "score" : 59.5, "model-ac" : "PF16207" }, { "signature" : { "accession" : "PTHR10825:SF72", "name" : "POLYCOMB GROUP PROTEIN PSC-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 361, "hmmStart" : 5, "hmmEnd" : 362, "hmmLength" : 1189, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 385, "location-fragments" : [ { "start" : 10, "end" : 361, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-96, "familyName" : "POLYCOMB GROUP PROTEIN PSC-RELATED", "score" : 326.2, "model-ac" : "PTHR10825:SF72" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 862, "end" : 924, "location-fragments" : [ { "start" : 862, "end" : 924, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 510, "end" : 583, "location-fragments" : [ { "start" : 510, "end" : 583, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 294, "end" : 319, "location-fragments" : [ { "start" : 294, "end" : 319, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 865, "end" : 879, "location-fragments" : [ { "start" : 865, "end" : 879, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 331, "end" : 348, "location-fragments" : [ { "start" : 331, "end" : 348, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57850", "name" : "RING/U-box", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 69, "hmmLength" : 78, "location-fragments" : [ { "start" : 15, "end" : 69, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.29E-12, "model-ac" : "0043836" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 660, "end" : 682, "location-fragments" : [ { "start" : 660, "end" : 682, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 434, "end" : 448, "location-fragments" : [ { "start" : 434, "end" : 448, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 382, "end" : 413, "location-fragments" : [ { "start" : 382, "end" : 413, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50089", "name" : "ZF_RING_2", "description" : "Zinc finger RING-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 23, "end" : 62, "score" : 11.176, "alignment" : "CVLCGGYFVDA-ASIVECLHTFCWTCIVKY--LEKNKFCPICD", "location-fragments" : [ { "start" : 23, "end" : 62, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50089" }, { "signature" : { "accession" : "PF13923", "name" : "zf-C3HC4_2", "description" : "Zinc finger, C3HC4 type (RING finger)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 23, "end" : 61, "hmmStart" : 2, "hmmEnd" : 40, "hmmLength" : 40, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.6E-8, "score" : 32.8, "envelopeStart" : 22, "envelopeEnd" : 61, "postProcessed" : true, "location-fragments" : [ { "start" : 23, "end" : 61, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-8, "score" : 33.8, "model-ac" : "PF13923" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 414, "end" : 431, "location-fragments" : [ { "start" : 414, "end" : 431, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00184", "name" : "ring_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 23, "end" : 61, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-4, "score" : 31.5, "location-fragments" : [ { "start" : 23, "end" : 61, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-4, "score" : 31.5, "model-ac" : "SM00184" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 522, "end" : 566, "location-fragments" : [ { "start" : 522, "end" : 566, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 357, "end" : 381, "location-fragments" : [ { "start" : 357, "end" : 381, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 629, "end" : 649, "location-fragments" : [ { "start" : 629, "end" : 649, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "cd16736", "name" : "RING-HC_PCGF4", "description" : "RING-HC_PCGF4", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 17, "end" : 70, "sites" : [ { "description" : "polypeptide substrate binding site", "numLocations" : 20, "siteLocations" : [ { "start" : 20, "end" : 20, "residue" : "Y" }, { "start" : 35, "end" : 35, "residue" : "S" }, { "start" : 28, "end" : 28, "residue" : "G" }, { "start" : 50, "end" : 50, "residue" : "K" }, { "start" : 41, "end" : 41, "residue" : "H" }, { "start" : 38, "end" : 38, "residue" : "E" }, { "start" : 49, "end" : 49, "residue" : "V" }, { "start" : 44, "end" : 44, "residue" : "C" }, { "start" : 45, "end" : 45, "residue" : "W" }, { "start" : 26, "end" : 26, "residue" : "C" }, { "start" : 37, "end" : 37, "residue" : "V" }, { "start" : 47, "end" : 47, "residue" : "C" }, { "start" : 22, "end" : 22, "residue" : "I" }, { "start" : 46, "end" : 46, "residue" : "T" }, { "start" : 40, "end" : 40, "residue" : "L" }, { "start" : 29, "end" : 29, "residue" : "Y" }, { "start" : 31, "end" : 31, "residue" : "V" }, { "start" : 39, "end" : 39, "residue" : "C" }, { "start" : 32, "end" : 32, "residue" : "D" }, { "start" : 34, "end" : 34, "residue" : "A" } ] }, { "description" : "Zn binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 41, "end" : 41, "residue" : "H" }, { "start" : 44, "end" : 44, "residue" : "C" }, { "start" : 26, "end" : 26, "residue" : "C" }, { "start" : 58, "end" : 58, "residue" : "C" }, { "start" : 23, "end" : 23, "residue" : "C" }, { "start" : 39, "end" : 39, "residue" : "C" }, { "start" : 47, "end" : 47, "residue" : "C" }, { "start" : 61, "end" : 61, "residue" : "C" } ] } ], "evalue" : 2.47851E-25, "score" : 97.7677, "location-fragments" : [ { "start" : 17, "end" : 70, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd16736" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 246, "end" : 293, "location-fragments" : [ { "start" : 246, "end" : 293, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 462, "end" : 485, "location-fragments" : [ { "start" : 462, "end" : 485, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.40.10", "name" : "Zinc/RING finger domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013083", "name" : "Znf_RING/FYVE/PHD", "description" : "Zinc finger, RING/FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 109, "hmmStart" : 5, "hmmEnd" : 98, "hmmLength" : 108, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-22, "score" : 80.0, "envelopeStart" : 7, "envelopeEnd" : 109, "postProcessed" : true, "location-fragments" : [ { "start" : 7, "end" : 109, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-22, "score" : 80.0, "model-ac" : "2cklA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 981, "end" : 1053, "location-fragments" : [ { "start" : 981, "end" : 1053, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 246, "end" : 496, "location-fragments" : [ { "start" : 246, "end" : 496, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd17082", "name" : "RAWUL_PCGF2_like", "description" : "RAWUL_PCGF2_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 127, "end" : 228, "sites" : [ { "description" : "key conserved lysine K27", "numLocations" : 1, "siteLocations" : [ { "start" : 178, "end" : 178, "residue" : "K" } ] }, { "description" : "key conserved lysines", "numLocations" : 2, "siteLocations" : [ { "start" : 178, "end" : 178, "residue" : "K" }, { "start" : 184, "end" : 184, "residue" : "K" } ] } ], "evalue" : 1.03122E-32, "score" : 120.519, "location-fragments" : [ { "start" : 127, "end" : 228, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd17082" } ], "xref" : [ { "name" : "XP_018910076.1 PREDICTED: dentin sialophosphoprotein-like [Bemisia tabaci]", "id" : "XP_018910076.1" } ] },{ "sequence" : "MDDGDGERQLQFYTAARKFENLTFSFCDCWPNADEHFIRCSCGEDSKDIDYEWSWDEASSSDSTVLYKENREVRFHPGYSSGTAAVRGDSTFKFGHVYYWEIKILTTLYGTDVMIGVGTPKVELNNSRFSFCSLLGADKESWGFSYKGKSQHNGVTEKYGSPFDKGSIIGIYLNMWTGRLEFFLNRMPLGVAYKVLQDQELYPMVCSTAAKSAVRIILTRSRPISLKLLSLENIGPSEELLREYLKTMPGLRNYVQNLWWIIKDTDEQSTSTSKQNNKHYQKWCGKRCFPSDGQEKNVRKIRNKCFVGTANLPGSSSDQADSCICRLRRYNPNRPHGPCWFCHEYL", "md5" : "cd74d1bf38f20d2bee3aca07fab83d51", "matches" : [ { "signature" : { "accession" : "PF00622", "name" : "SPRY", "description" : "SPRY domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR003877", "name" : "SPRY_dom", "description" : "SPRY domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 98, "end" : 218, "hmmStart" : 2, "hmmEnd" : 117, "hmmLength" : 120, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-21, "score" : 76.6, "envelopeStart" : 97, "envelopeEnd" : 221, "postProcessed" : true, "location-fragments" : [ { "start" : 98, "end" : 218, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.2E-22, "score" : 77.6, "model-ac" : "PF00622" }, { "signature" : { "accession" : "PTHR12245", "name" : "SPRY DOMAIN CONTAINING SOCS BOX PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 38, "end" : 248, "hmmStart" : 154, "hmmEnd" : 346, "hmmLength" : 381, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 300, "location-fragments" : [ { "start" : 38, "end" : 248, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-59, "familyName" : "SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3", "score" : 202.3, "model-ac" : "PTHR12245" }, { "signature" : { "accession" : "SM00449", "name" : "SPRY_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003877", "name" : "SPRY_dom", "description" : "SPRY domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 95, "end" : 222, "hmmStart" : 1, "hmmEnd" : 145, "hmmLength" : 145, "hmmBounds" : "COMPLETE", "evalue" : 5.0E-21, "score" : 85.8, "location-fragments" : [ { "start" : 95, "end" : 222, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-21, "score" : 85.8, "model-ac" : "SM00449" }, { "signature" : { "accession" : "cd12876", "name" : "SPRY_SOCS3", "description" : "SPRY_SOCS3", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR035754", "name" : "SPRY_SPSB3", "description" : "SPRY domain-containing SOCS box protein 3, SPRY domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Neddylation", "databaseName" : "Reactome", "id" : "R-HSA-8951664" } ] } }, "locations" : [ { "start" : 52, "end" : 234, "sites" : [ ], "evalue" : 2.8798E-94, "score" : 276.349, "location-fragments" : [ { "start" : 52, "end" : 234, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12876" }, { "signature" : { "accession" : "SSF49899", "name" : "Concanavalin A-like lectins/glucanases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR013320", "name" : "ConA-like_dom_sf", "description" : "Concanavalin A-like lectin/glucanase domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 49, "end" : 221, "hmmLength" : 217, "location-fragments" : [ { "start" : 49, "end" : 221, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.78E-43, "model-ac" : "0052728" }, { "signature" : { "accession" : "G3DSA:2.60.120.920", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR043136", "name" : "B30.2/SPRY_sf", "description" : "B30.2/SPRY domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 49, "end" : 232, "hmmStart" : 5, "hmmEnd" : 155, "hmmLength" : 205, "hmmBounds" : "COMPLETE", "evalue" : 4.5E-33, "score" : 116.6, "envelopeStart" : 49, "envelopeEnd" : 232, "postProcessed" : true, "location-fragments" : [ { "start" : 49, "end" : 232, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-33, "score" : 117.2, "model-ac" : "4xw3A00" }, { "signature" : { "accession" : "PTHR12245:SF5", "name" : "SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 38, "end" : 248, "hmmStart" : 154, "hmmEnd" : 346, "hmmLength" : 381, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 300, "location-fragments" : [ { "start" : 38, "end" : 248, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-59, "familyName" : "SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3", "score" : 202.3, "model-ac" : "PTHR12245:SF5" }, { "signature" : { "accession" : "PS50188", "name" : "B302_SPRY", "description" : "B30.2/SPRY domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001870", "name" : "B30.2/SPRY", "description" : "B30.2/SPRY domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 33, "end" : 223, "score" : 19.354, "alignment" : "ADEHFIRCSCGEDSKDIDYEWSWDEASSSDSTVLYKENREVRFHP---------GYSSGTAAVRGDSTFKfGHVYYWEIKILTTlyGTDVMIGVGTPKVELNNSRFsfcsLLGaDKESWGFSYKGKSQHNGVTEK--YGSPFDKGSIIGIYLNMWTGRLEFFLNRMP-LGVAYK-VLQDQELYPMVCSTAAKSAVRIILTRSRP", "location-fragments" : [ { "start" : 33, "end" : 223, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50188" } ], "xref" : [ { "name" : "XP_018909604.1 PREDICTED: SPRY domain-containing SOCS box protein 3 [Bemisia tabaci]", "id" : "XP_018909604.1" } ] },{ "sequence" : "MNSLARQRSCSSGSSVELEQLEELWSQEEKDMDPAEENEPRSESIPLAKKFEILAKARHIFVGKLARNPHPVTGGDRIMYARSQQRNFTKMPVTGGTPVTQEVAIAFRSIVFGTSVAPPRGEWLRTGFVFRDADKELAYGLKAPRNGCRGLLSVVQAYILKQLLFERKDFKKNEPVMQPEMLLRPSRGKQLEALWLAISDILWRIGEKTKAVVCLPQDQPYVSHSLNYFQDSVTEKLHIFEIANLEELQIFIKRYIHLFLEEPGPGALLLLYSAVATRGTKNVISDIMDEKGYLVTGAEEGSQSIIMLLLTGRATPYLHNGVVYVGDEEHYAIPQFGVLQRSEIGFLLFDEGVEEKAPGSRLKTPSLPIWVVCCLGHFGVIFNTNRELLRNYHAERRFELIYYTCGGSQCQLTVDTRHDGSSTQVSTSEDTASSSLANLEKLIHTKWQDAHIHWNGTSNFI", "md5" : "bb5f369a92bda7a86aada58fe16c626a", "matches" : [ { "signature" : { "accession" : "PTHR12473", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR039785", "name" : "MINY3/4", "description" : "Deubiquitinating enzyme MINDY-3/4", "type" : "FAMILY", "goXRefs" : [ { "name" : "Lys48-specific deubiquitinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:1990380" }, { "name" : "protein K48-linked deubiquitination", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0071108" }, { "name" : "thiol-dependent ubiquitin-specific protease activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004843" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 77, "end" : 458, "hmmStart" : 179, "hmmEnd" : 549, "hmmLength" : 552, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 461, "location-fragments" : [ { "start" : 77, "end" : 458, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-104, "familyName" : "", "score" : 353.6, "model-ac" : "PTHR12473" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 38, "location-fragments" : [ { "start" : 18, "end" : 38, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF13898", "name" : "DUF4205", "description" : "Domain of unknown function (DUF4205)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR025257", "name" : "MINDY-3/4_CD", "description" : "Deubiquitinating enzyme MINDY-3/4, conserved domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 108, "end" : 456, "hmmStart" : 1, "hmmEnd" : 351, "hmmLength" : 351, "hmmBounds" : "COMPLETE", "evalue" : 2.0E-129, "score" : 431.5, "envelopeStart" : 108, "envelopeEnd" : 456, "postProcessed" : true, "location-fragments" : [ { "start" : 108, "end" : 456, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-129, "score" : 431.7, "model-ac" : "PF13898" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 21, "location-fragments" : [ { "start" : 1, "end" : 21, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM01174", "name" : "DUF4205_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR025257", "name" : "MINDY-3/4_CD", "description" : "Deubiquitinating enzyme MINDY-3/4, conserved domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 108, "end" : 456, "hmmStart" : 1, "hmmEnd" : 438, "hmmLength" : 438, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-131, "score" : 452.1, "location-fragments" : [ { "start" : 108, "end" : 456, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-131, "score" : 452.1, "model-ac" : "SM01174" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 43, "location-fragments" : [ { "start" : 1, "end" : 43, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12473:SF4", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 77, "end" : 458, "hmmStart" : 179, "hmmEnd" : 549, "hmmLength" : 552, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 461, "location-fragments" : [ { "start" : 77, "end" : 458, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-104, "familyName" : "", "score" : 353.6, "model-ac" : "PTHR12473:SF4" } ], "xref" : [ { "name" : "XP_018910115.1 PREDICTED: protein FAM188B2 isoform X1 [Bemisia tabaci]", "id" : "XP_018910115.1" } ] },{ "sequence" : "MKLTKYLHRVYLVSLNCLLTFAASVENSTVEPTTARAERSLGSGLAFVDANSIDRDDPAASLDGVYSECLLNLSFPCLQKKIIVFLDRLGRKKQVSLIGDFLTVVRTGPVSATVSEETTARRDESSLRSVIDGQVDRFFETHVLRVRVPSFLDDPGTENTVVDIDFGTGASTSEGRGKKGGKMKGMKKMMMMMGMMMCMKMAMMGPLMMGLIGLKAVKALILSAVSLTISKILLLKKLKGGGGGGGGGGGWKEAGGDSSGQGWDRSIESSYAHKTAFSAYAPIES", "md5" : "55c64033a7800497f8fbb57b61d960ff", "matches" : [ { "signature" : { "accession" : "PTHR21879", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR012464", "name" : "DUF1676", "description" : "Protein of unknown function DUF1676", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 57, "end" : 282, "hmmStart" : 31, "hmmEnd" : 253, "hmmLength" : 266, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 6, "envelopeEnd" : 285, "location-fragments" : [ { "start" : 57, "end" : 282, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-33, "familyName" : "UNCHARACTERIZED", "score" : 117.5, "model-ac" : "PTHR21879" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 246, "end" : 267, "location-fragments" : [ { "start" : 246, "end" : 267, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF07898", "name" : "DUF1676", "description" : "Protein of unknown function (DUF1676)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR012464", "name" : "DUF1676", "description" : "Protein of unknown function DUF1676", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 68, "end" : 237, "hmmStart" : 1, "hmmEnd" : 172, "hmmLength" : 172, "hmmBounds" : "COMPLETE", "evalue" : 8.0E-36, "score" : 123.7, "envelopeStart" : 68, "envelopeEnd" : 237, "postProcessed" : true, "location-fragments" : [ { "start" : 68, "end" : 237, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.1E-36, "score" : 124.0, "model-ac" : "PF07898" } ], "xref" : [ { "name" : "XP_018909941.1 PREDICTED: uncharacterized protein LOC109039066 [Bemisia tabaci]", "id" : "XP_018909941.1" } ] },{ "sequence" : "MTGRIGVGSARVPFALALCMLFTPCNWSHAKQQVTLAHGTVFLDSADAFSVLDITTAETSSSYYSMSIFMISPAFDRR", "md5" : "c136759661145c841d244359139076a3", "matches" : [ ], "xref" : [ { "name" : "XP_018910224.1 PREDICTED: uncharacterized protein LOC109039272 [Bemisia tabaci]", "id" : "XP_018910224.1" }, { "name" : "XP_018910223.1 PREDICTED: uncharacterized protein LOC109039272 [Bemisia tabaci]", "id" : "XP_018910223.1" } ] },{ "sequence" : "MEQIWHSTSKTSGRVVLLAIWLSIIPWFCSAQSWKKLDDARYSDGSDDVSVEESVSKNASLYLDRSVVGEDFNIELNFFRWGTCQRADLSKSLKCCETDINTDEDRRYYACEDIPADTASKFIRVRLEVGDLQRSLMSRYNREVNSLFNASENPAWAEVSRRPIGELGDVPFSYFLGRPVEGLLRRALNRSLEESLDPANDRRRIEKRLQDLRQAVNAALNHTLNDIVNESLDYVFQLDDQDFDYVSGRQWFRIRNLSLENIFDSMLQANGANMTGVETLLRIAWRLFLNQQQESFEKFLSNPGEVVAWIFNTYMNLFGNNRTGIFNREALRGFVQYYTATESYRVTIPLCYAPIPASSLCWNINFMINTNKWTVRKTVNLAAESNLLAADPFVLELFDMDLNLTGFRERRQEGVCANGRISMLDMDGYPFPKFELGCHPVFYHPLQYVDQVLCLLYERTVTSRNSLRNTTLGKVCIDPIQATLMHELTRNFIRMTVRNNNLQPSSNKVCKNMVYQLHTLGAGTPRDELMSRAITEMLSYSITNLLGVRSDRRTILNFVRLARAAPILMDAWGAIAQNSNSTEQFNRNLMECGVLLLQHGEEHRTLALHPTPPPQPPTSPPNRLRDLLRRRISDHRLAPPAPSSNRRIRQVDDLEMSQWDDLSGTREEGQIGDPRDDDIPTIQQIQGQSALKNSLAALFRQLDEMRFRLRDFLDGQRVNFESRLDGLWDRYANTIRAWLESFLARVLGTVTQYAPLITRHPG", "md5" : "a1deba6eabfb58a2af6a46d06eca0638", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 202, "end" : 222, "location-fragments" : [ { "start" : 202, "end" : 222, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 603, "end" : 650, "location-fragments" : [ { "start" : 603, "end" : 650, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909728.1 PREDICTED: uncharacterized protein LOC109038914 isoform X1 [Bemisia tabaci]", "id" : "XP_018909728.1" } ] },{ "sequence" : "MTAVMSPAIPTSDSVKSLCRGDSAGVAKIKPEFVVENHVRSLAIDCVSASDKRKLAEINSDDEDNSSRKKHKNEKKKMFKGQNKSRGPTFKQSKENTLCPILVDVKKGDPTPVCHYDNCKFIHDVQSYLSCKPPDLGPQCHVFDLKGHCPRGVTCRYGKSHISEDGFNIINETLQAEWNAKSKTSTTQNFTKELQRALQKRTYNFEKSERIISAVKDGKIDLPSKASESEKNVETTKNCEMKTNNGEKCMISTESNLESMSQSEQEADVSVGSKEQLGPVSDTDLIKLRPAEKKKIDWTDKLYLSPLTTVGNLPFRRICKEFGADITCGEMALATSLLQGRKQEWALAKRHESEDLFGAQICGSNMNTMTRCAQVLQENANIDFVDINLGCPIDLIFQKGAGSGLLRQEKILKSVVVSMNQVLDIPLTVKVRTGIHKDKKIADQLVPKFRDWGVSLITLHGRTREQRYTRSADWGYIEKCAQLCKPVPLFGNGDILSFSDYNTAREICPSIAGTMIGRGALIKPWIFTEIKEQRDWDISSSERFDIIKKYSNYGLEHWGSDTQGVENTRKFLLEWLSFFHRYIPYGLLENPPHQINQRPPMFKGRDDLETLLASPNCADWIRITEMLLGKVPDGFNFLPKHKANSWK", "md5" : "3733503f13dd0eb5dff0f73032d5c5a2", "matches" : [ { "signature" : { "accession" : "PS01136", "name" : "UPF0034", "description" : "Uncharacterized protein family UPF0034 signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018517", "name" : "tRNA_hU_synthase_CS", "description" : "tRNA-dihydrouridine synthase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "tRNA dihydrouridine synthase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0017150" }, { "name" : "flavin adenine dinucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0050660" }, { "name" : "tRNA processing", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0008033" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 385, "end" : 403, "level" : "STRONG", "cigarAlignment" : "4M1I3M3I1M5I2M", "alignment" : "VDINlGCPidlIfqkgaGS", "location-fragments" : [ { "start" : 385, "end" : 403, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01136" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 58, "end" : 90, "location-fragments" : [ { "start" : 58, "end" : 90, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd02801", "name" : "DUS_like_FMN", "description" : "DUS_like_FMN", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR035587", "name" : "DUS-like_FMN-bd", "description" : "DUS-like, FMN-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 301, "end" : 535, "sites" : [ { "description" : "substrate binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 494, "end" : 494, "residue" : "D" }, { "start" : 392, "end" : 392, "residue" : "P" }, { "start" : 459, "end" : 459, "residue" : "L" }, { "start" : 463, "end" : 463, "residue" : "T" }, { "start" : 430, "end" : 430, "residue" : "K" }, { "start" : 493, "end" : 493, "residue" : "G" } ] }, { "description" : "catalytic residues", "numLocations" : 4, "siteLocations" : [ { "start" : 460, "end" : 460, "residue" : "H" }, { "start" : 432, "end" : 432, "residue" : "R" }, { "start" : 462, "end" : 462, "residue" : "R" }, { "start" : 391, "end" : 391, "residue" : "C" } ] }, { "description" : "active site", "numLocations" : 12, "siteLocations" : [ { "start" : 360, "end" : 360, "residue" : "Q" }, { "start" : 460, "end" : 460, "residue" : "H" }, { "start" : 494, "end" : 494, "residue" : "D" }, { "start" : 432, "end" : 432, "residue" : "R" }, { "start" : 392, "end" : 392, "residue" : "P" }, { "start" : 462, "end" : 462, "residue" : "R" }, { "start" : 518, "end" : 518, "residue" : "R" }, { "start" : 459, "end" : 459, "residue" : "L" }, { "start" : 463, "end" : 463, "residue" : "T" }, { "start" : 430, "end" : 430, "residue" : "K" }, { "start" : 391, "end" : 391, "residue" : "C" }, { "start" : 493, "end" : 493, "residue" : "G" } ] }, { "description" : "FMN binding site", "numLocations" : 12, "siteLocations" : [ { "start" : 360, "end" : 360, "residue" : "Q" }, { "start" : 460, "end" : 460, "residue" : "H" }, { "start" : 494, "end" : 494, "residue" : "D" }, { "start" : 305, "end" : 305, "residue" : "S" }, { "start" : 518, "end" : 518, "residue" : "R" }, { "start" : 331, "end" : 331, "residue" : "M" }, { "start" : 307, "end" : 307, "residue" : "L" }, { "start" : 430, "end" : 430, "residue" : "K" }, { "start" : 517, "end" : 517, "residue" : "G" }, { "start" : 388, "end" : 388, "residue" : "N" }, { "start" : 492, "end" : 492, "residue" : "N" }, { "start" : 306, "end" : 306, "residue" : "P" } ] } ], "evalue" : 6.69328E-95, "score" : 289.78, "location-fragments" : [ { "start" : 301, "end" : 535, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd02801" }, { "signature" : { "accession" : "PF01207", "name" : "Dus", "description" : "Dihydrouridine synthase (Dus)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001269", "name" : "tRNA_hU_synthase", "description" : "tRNA-dihydrouridine synthase", "type" : "FAMILY", "goXRefs" : [ { "name" : "tRNA dihydrouridine synthase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0017150" }, { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "flavin adenine dinucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0050660" }, { "name" : "tRNA processing", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0008033" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 304, "end" : 561, "hmmStart" : 2, "hmmEnd" : 261, "hmmLength" : 310, "hmmBounds" : "INCOMPLETE", "evalue" : 5.4E-55, "score" : 186.7, "envelopeStart" : 303, "envelopeEnd" : 580, "postProcessed" : true, "location-fragments" : [ { "start" : 304, "end" : 561, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-55, "score" : 187.6, "model-ac" : "PF01207" }, { "signature" : { "accession" : "G3DSA:3.20.20.70", "name" : "Aldolase class I", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013785", "name" : "Aldolase_TIM", "description" : "Aldolase-type TIM barrel", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 297, "end" : 538, "hmmStart" : 5, "hmmEnd" : 228, "hmmLength" : 238, "hmmBounds" : "COMPLETE", "evalue" : 9.0E-78, "score" : 262.6, "envelopeStart" : 297, "envelopeEnd" : 538, "postProcessed" : true, "location-fragments" : [ { "start" : 297, "end" : 538, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-78, "score" : 263.4, "model-ac" : "1vhnA01" }, { "signature" : { "accession" : "PTHR45846:SF1", "name" : "TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 646, "hmmStart" : 7, "hmmEnd" : 521, "hmmLength" : 527, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 20, "envelopeEnd" : 647, "location-fragments" : [ { "start" : 24, "end" : 646, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-218, "familyName" : "TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE", "score" : 729.2, "model-ac" : "PTHR45846:SF1" }, { "signature" : { "accession" : "SSF51395", "name" : "FMN-linked oxidoreductases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 301, "end" : 614, "hmmLength" : 305, "location-fragments" : [ { "start" : 301, "end" : 614, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-66, "model-ac" : "0044760" }, { "signature" : { "accession" : "PS50103", "name" : "ZF_C3H1", "description" : "Zinc finger C3H1-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000571", "name" : "Znf_CCCH", "description" : "Zinc finger, CCCH-type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "metal ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046872" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 134, "end" : 164, "score" : 10.305, "alignment" : "PDLGPQCHVFDlKGHCPRGVTCRYgkSHISE", "location-fragments" : [ { "start" : 134, "end" : 164, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50103" }, { "signature" : { "accession" : "PTHR45846", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 646, "hmmStart" : 7, "hmmEnd" : 521, "hmmLength" : 527, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 20, "envelopeEnd" : 647, "location-fragments" : [ { "start" : 24, "end" : 646, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-218, "familyName" : "TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE", "score" : 729.2, "model-ac" : "PTHR45846" } ], "xref" : [ { "name" : "XP_018909589.1 PREDICTED: tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like [Bemisia tabaci]", "id" : "XP_018909589.1" } ] },{ "sequence" : "MMSSENLKYIYHLPYHVRKKLCTVLDVNDKWEELGGMHMELDNACLYHIGQAVKRKSSPTNELLQLWETYNHTIEELFILLSRMQHYQAMSILKPYVDPKYHKLIFEGEENLSRLLLADKCENIAPHLQQGYTETNEKKNLDLEGNLNIQKETGVKDKLCLPKTENKISNNNDQAANIEIPKKTTDLSAASFAAEACTPCVPYKELEIATNNWNSSNILGRGGFGTVFVGTWKSTKVAIKRLEPHKSLGKGANLELQKQLSYRELKYLNDCRHDNILALFAFSTDGDRFCLVYQYMLNGSLEDRLLCRQNTKPLTWSQRYNIARGTALGLQFLHDRKPPLIHGDIKSANILLDKSFEPKIGDFGLTQEGPLQHYTSVKVSKVHGTKAYLPEEFFRGKKFSVKVDVYSFGVVLFEIATGLRAYDDKRPQKLLRDFVHEYDKSKLHELLDHKAETDELKASTGFLQLGLICTHSSAKQRLEMFTVLTQIDAIIATQKITSRAQQNLHLMQMNTFTPSNPYEMQLMHDFLRQQHRLSIPSPSPSTRSSSPGTVNAPQRRSSSPAKLTHVQGTIFEEAAPLKPDDGVSMPTNMLLQRRTITPPNTNASLQRKSGVASMEQSPRMPLSVTVDSSLSQNSSVPASNLPASSLPTSSPLVASIPASSLPTISHPASSLPAFSLPASSGSIQKSEPPVSSANQAPVSSDIEAKSLPSSSLPSIVVNQLQSNQSIAIEPKDLLPITSISTLYSSSDEISSIIEPESDSAGALPPVYETDESNRGSENHTGIDKSNEIIPLISALLNSEEDMELQS", "md5" : "8bdcf39a91fefab83d98e55a0c8aa556", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 532, "end" : 565, "location-fragments" : [ { "start" : 532, "end" : 565, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 680, "end" : 705, "location-fragments" : [ { "start" : 680, "end" : 705, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR24419:SF33", "name" : "SERINE/THREONINE-PROTEIN KINASE PELLE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 643, "hmmStart" : 2, "hmmEnd" : 637, "hmmLength" : 688, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 691, "location-fragments" : [ { "start" : 3, "end" : 643, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-173, "familyName" : "SERINE/THREONINE-PROTEIN KINASE PELLE", "score" : 582.0, "model-ac" : "PTHR24419:SF33" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 588, "end" : 631, "location-fragments" : [ { "start" : 588, "end" : 631, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.10.510.10", "name" : "Transferase(Phosphotransferase) domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 296, "end" : 514, "hmmStart" : 1, "hmmEnd" : 208, "hmmLength" : 224, "hmmBounds" : "COMPLETE", "evalue" : 8.5E-49, "score" : 167.6, "envelopeStart" : 296, "envelopeEnd" : 514, "postProcessed" : true, "location-fragments" : [ { "start" : 296, "end" : 514, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-49, "score" : 168.3, "model-ac" : "4l68A02" }, { "signature" : { "accession" : "cd08307", "name" : "Death_Pelle", "description" : "Death_Pelle", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR037924", "name" : "Pelle_death", "description" : "Pelle, death domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Relaxin signaling pathway", "databaseName" : "KEGG", "id" : "04926+2.7.11.1" }, { "name" : "PI3K-Akt signaling pathway", "databaseName" : "KEGG", "id" : "04151+2.7.11.1" }, { "name" : "mTOR signaling pathway", "databaseName" : "KEGG", "id" : "04150+2.7.11.1" }, { "name" : "Thermogenesis", "databaseName" : "KEGG", "id" : "04714+2.7.11.1" }, { "name" : "Human immunodeficiency virus 1 infection", "databaseName" : "KEGG", "id" : "05170+2.7.11.1" }, { "name" : "Human papillomavirus infection", "databaseName" : "KEGG", "id" : "05165+2.7.11.1" }, { "name" : "Human cytomegalovirus infection", "databaseName" : "KEGG", "id" : "05163+2.7.11.1" } ] } }, "locations" : [ { "start" : 8, "end" : 104, "sites" : [ { "description" : "Pelle-Tube interaction site", "numLocations" : 18, "siteLocations" : [ { "start" : 78, "end" : 78, "residue" : "F" }, { "start" : 80, "end" : 80, "residue" : "L" }, { "start" : 101, "end" : 101, "residue" : "Y" }, { "start" : 76, "end" : 76, "residue" : "E" }, { "start" : 72, "end" : 72, "residue" : "H" }, { "start" : 82, "end" : 82, "residue" : "S" }, { "start" : 67, "end" : 67, "residue" : "W" }, { "start" : 69, "end" : 69, "residue" : "T" }, { "start" : 41, "end" : 41, "residue" : "L" }, { "start" : 66, "end" : 66, "residue" : "L" }, { "start" : 79, "end" : 79, "residue" : "I" }, { "start" : 65, "end" : 65, "residue" : "Q" }, { "start" : 48, "end" : 48, "residue" : "H" }, { "start" : 11, "end" : 11, "residue" : "Y" }, { "start" : 38, "end" : 38, "residue" : "H" }, { "start" : 70, "end" : 70, "residue" : "Y" }, { "start" : 71, "end" : 71, "residue" : "N" }, { "start" : 45, "end" : 45, "residue" : "C" } ] } ], "evalue" : 2.92038E-44, "score" : 152.45, "location-fragments" : [ { "start" : 8, "end" : 104, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd08307" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 526, "end" : 631, "location-fragments" : [ { "start" : 526, "end" : 631, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00531", "name" : "Death", "description" : "Death domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000488", "name" : "Death_domain", "description" : "Death domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" }, { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 18, "end" : 95, "hmmStart" : 1, "hmmEnd" : 84, "hmmLength" : 86, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.0E-7, "score" : 31.1, "envelopeStart" : 18, "envelopeEnd" : 97, "postProcessed" : true, "location-fragments" : [ { "start" : 18, "end" : 95, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.1E-8, "score" : 32.2, "model-ac" : "PF00531" }, { "signature" : { "accession" : "PS50011", "name" : "PROTEIN_KINASE_DOM", "description" : "Protein kinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 213, "end" : 491, "score" : 33.107, "alignment" : "WNSSNILGRGGFGTVFVGTWK--STKVAIKRLEPHKSLGKganlelQKQLSYRELKYLNDCRHDNILALFAFSTDGDRFCLVYQYMLNGSLEDRLLCRQNTkpLTWSQRYNIARGTALGLQFLHDRkpPLIHGDIKSANILLDKSFEPKIGDFGLTQEGplQHYTSvKVSKVHGTKAYLPEEFFR-GKKFSVKVDVYSFGVVLFEIATGLRAYDD-KRPQKLLRDFVHE--------YDKsklhelldhkaetdelkASTGFLQLGLICTHSSAKQRLEMFTVLTqiDAII", "location-fragments" : [ { "start" : 213, "end" : 491, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50011" }, { "signature" : { "accession" : "SM00220", "name" : "serkin_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 213, "end" : 491, "hmmStart" : 1, "hmmEnd" : 231, "hmmLength" : 231, "hmmBounds" : "COMPLETE", "evalue" : 4.7E-29, "score" : 112.5, "location-fragments" : [ { "start" : 213, "end" : 491, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-29, "score" : 112.5, "model-ac" : "SM00220" }, { "signature" : { "accession" : "SSF47986", "name" : "DEATH domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011029", "name" : "DEATH-like_dom_sf", "description" : "Death-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 105, "hmmLength" : 127, "location-fragments" : [ { "start" : 6, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.12E-25, "model-ac" : "0050544" }, { "signature" : { "accession" : "PS00108", "name" : "PROTEIN_KINASE_ST", "description" : "Serine/Threonine protein kinases active-site signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR008271", "name" : "Ser/Thr_kinase_AS", "description" : "Serine/threonine-protein kinase, active site", "type" : "ACTIVE_SITE", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 340, "end" : 352, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I3M2I4M", "alignment" : "LiHgDIKsaNILL", "location-fragments" : [ { "start" : 340, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00108" }, { "signature" : { "accession" : "PTHR24419", "name" : "INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 643, "hmmStart" : 2, "hmmEnd" : 637, "hmmLength" : 688, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 691, "location-fragments" : [ { "start" : 3, "end" : 643, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-173, "familyName" : "SERINE/THREONINE-PROTEIN KINASE PELLE", "score" : 582.0, "model-ac" : "PTHR24419" }, { "signature" : { "accession" : "G3DSA:1.10.533.10", "name" : "Death Domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 105, "hmmStart" : 9, "hmmEnd" : 108, "hmmLength" : 108, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-30, "score" : 107.2, "envelopeStart" : 1, "envelopeEnd" : 105, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.6E-31, "score" : 108.2, "model-ac" : "1d2zA00" }, { "signature" : { "accession" : "cd14066", "name" : "STKc_IRAK", "description" : "STKc_IRAK", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 219, "end" : 484, "sites" : [ { "description" : "activation loop (A-loop)", "numLocations" : 16, "siteLocations" : [ { "start" : 364, "end" : 364, "residue" : "G" }, { "start" : 386, "end" : 386, "residue" : "K" }, { "start" : 381, "end" : 381, "residue" : "K" }, { "start" : 385, "end" : 385, "residue" : "T" }, { "start" : 383, "end" : 383, "residue" : "H" }, { "start" : 384, "end" : 384, "residue" : "G" }, { "start" : 368, "end" : 368, "residue" : "E" }, { "start" : 382, "end" : 382, "residue" : "V" }, { "start" : 387, "end" : 387, "residue" : "A" }, { "start" : 361, "end" : 361, "residue" : "G" }, { "start" : 366, "end" : 366, "residue" : "T" }, { "start" : 365, "end" : 365, "residue" : "L" }, { "start" : 380, "end" : 380, "residue" : "S" }, { "start" : 362, "end" : 362, "residue" : "D" }, { "start" : 367, "end" : 367, "residue" : "Q" }, { "start" : 363, "end" : 363, "residue" : "F" } ] }, { "description" : "polypeptide substrate binding site", "numLocations" : 11, "siteLocations" : [ { "start" : 346, "end" : 346, "residue" : "K" }, { "start" : 387, "end" : 387, "residue" : "A" }, { "start" : 386, "end" : 386, "residue" : "K" }, { "start" : 302, "end" : 302, "residue" : "E" }, { "start" : 365, "end" : 365, "residue" : "L" }, { "start" : 385, "end" : 385, "residue" : "T" }, { "start" : 300, "end" : 300, "residue" : "S" }, { "start" : 223, "end" : 223, "residue" : "G" }, { "start" : 384, "end" : 384, "residue" : "G" }, { "start" : 348, "end" : 348, "residue" : "A" }, { "start" : 344, "end" : 344, "residue" : "D" } ] }, { "description" : "ATP binding site", "numLocations" : 20, "siteLocations" : [ { "start" : 220, "end" : 220, "residue" : "G" }, { "start" : 351, "end" : 351, "residue" : "L" }, { "start" : 296, "end" : 296, "residue" : "M" }, { "start" : 277, "end" : 277, "residue" : "L" }, { "start" : 293, "end" : 293, "residue" : "Y" }, { "start" : 344, "end" : 344, "residue" : "D" }, { "start" : 346, "end" : 346, "residue" : "K" }, { "start" : 295, "end" : 295, "residue" : "Y" }, { "start" : 349, "end" : 349, "residue" : "N" }, { "start" : 294, "end" : 294, "residue" : "Q" }, { "start" : 240, "end" : 240, "residue" : "K" }, { "start" : 300, "end" : 300, "residue" : "S" }, { "start" : 223, "end" : 223, "residue" : "G" }, { "start" : 238, "end" : 238, "residue" : "A" }, { "start" : 362, "end" : 362, "residue" : "D" }, { "start" : 219, "end" : 219, "residue" : "L" }, { "start" : 348, "end" : 348, "residue" : "A" }, { "start" : 222, "end" : 222, "residue" : "G" }, { "start" : 221, "end" : 221, "residue" : "R" }, { "start" : 227, "end" : 227, "residue" : "V" } ] }, { "description" : "active site", "numLocations" : 26, "siteLocations" : [ { "start" : 220, "end" : 220, "residue" : "G" }, { "start" : 293, "end" : 293, "residue" : "Y" }, { "start" : 344, "end" : 344, "residue" : "D" }, { "start" : 387, "end" : 387, "residue" : "A" }, { "start" : 295, "end" : 295, "residue" : "Y" }, { "start" : 302, "end" : 302, "residue" : "E" }, { "start" : 294, "end" : 294, "residue" : "Q" }, { "start" : 300, "end" : 300, "residue" : "S" }, { "start" : 223, "end" : 223, "residue" : "G" }, { "start" : 238, "end" : 238, "residue" : "A" }, { "start" : 219, "end" : 219, "residue" : "L" }, { "start" : 222, "end" : 222, "residue" : "G" }, { "start" : 227, "end" : 227, "residue" : "V" }, { "start" : 351, "end" : 351, "residue" : "L" }, { "start" : 386, "end" : 386, "residue" : "K" }, { "start" : 296, "end" : 296, "residue" : "M" }, { "start" : 385, "end" : 385, "residue" : "T" }, { "start" : 277, "end" : 277, "residue" : "L" }, { "start" : 384, "end" : 384, "residue" : "G" }, { "start" : 346, "end" : 346, "residue" : "K" }, { "start" : 349, "end" : 349, "residue" : "N" }, { "start" : 240, "end" : 240, "residue" : "K" }, { "start" : 365, "end" : 365, "residue" : "L" }, { "start" : 362, "end" : 362, "residue" : "D" }, { "start" : 348, "end" : 348, "residue" : "A" }, { "start" : 221, "end" : 221, "residue" : "R" } ] } ], "evalue" : 2.18457E-89, "score" : 281.084, "location-fragments" : [ { "start" : 219, "end" : 484, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd14066" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 753, "end" : 785, "location-fragments" : [ { "start" : 753, "end" : 785, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS00107", "name" : "PROTEIN_KINASE_ATP", "description" : "Protein kinases ATP-binding region signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017441", "name" : "Protein_kinase_ATP_BS", "description" : "Protein kinase, ATP binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 219, "end" : 240, "level" : "STRONG", "cigarAlignment" : "10M1I1M6I4M", "alignment" : "LGRGGFGTVFvGtwkstkVAIK", "location-fragments" : [ { "start" : 219, "end" : 240, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00107" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 197, "end" : 485, "hmmLength" : 326, "location-fragments" : [ { "start" : 197, "end" : 485, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.34E-64, "model-ac" : "0035371" }, { "signature" : { "accession" : "G3DSA:3.30.200.20", "name" : "Phosphorylase Kinase; domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 195, "end" : 295, "hmmStart" : 9, "hmmEnd" : 105, "hmmLength" : 105, "hmmBounds" : "COMPLETE", "evalue" : 6.6E-22, "score" : 79.6, "envelopeStart" : 195, "envelopeEnd" : 295, "postProcessed" : true, "location-fragments" : [ { "start" : 195, "end" : 295, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-22, "score" : 80.9, "model-ac" : "2oibA01" }, { "signature" : { "accession" : "PF00069", "name" : "Pkinase", "description" : "Protein kinase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 215, "end" : 483, "hmmStart" : 3, "hmmEnd" : 258, "hmmLength" : 264, "hmmBounds" : "INCOMPLETE", "evalue" : 4.9E-40, "score" : 137.6, "envelopeStart" : 213, "envelopeEnd" : 487, "postProcessed" : true, "location-fragments" : [ { "start" : 215, "end" : 483, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-40, "score" : 138.4, "model-ac" : "PF00069" } ], "xref" : [ { "name" : "XP_018910088.1 PREDICTED: serine/threonine-protein kinase pelle-like [Bemisia tabaci]", "id" : "XP_018910088.1" } ] },{ "sequence" : "MRPTWSWVILSFLAIVQGSVGFKALFLFPFPAKSHFGSLSPLAEELARRGHQVTVVSHFPKKNALYKEIIMDSTEFHKQFNNNNVNMTELGTANPLISRAFMYTMFNKFAELSVSAKEMQELIASKEEFDIIAGEVSFFQPSLLAFAHRFQAPFVDLSPTSPFTHVSSFMGNPFSFSYIPDTLLTLSDSMSFLERLENTVNGLWDLAWFNWYFAPAQDAIIKKHFKYPGVEKIPSVSELIKNISLSLVNSHFSIGYSRPFSPNMIEIAGMHLKPVQKLPKDLQGFMDAAENGVVYFSLGSVLKEEDIGEGRLLAIADALKRLKQRVIVKVGAAAAKYFEGAKNLHILSWAPQQEILAHPKLLVFITHGGYNSLIEATRAGVPVLGLPVFGDQPRNIRFYETRGIGKGLDLGFTADQFYDSIMHIITTPSYRENAKEISRRTQDRPMSPLDTAVFWVEYVVRHKGAHHLKPVSANLPLYQYALLDIIVVLLLAVFLVYKLICKLYRLLCGTKKTKKEGVKKKTN", "md5" : "5547d755c837c1ce08a042c232d6c07c", "matches" : [ { "signature" : { "accession" : "PTHR11926", "name" : "GLUCOSYL/GLUCURONOSYL TRANSFERASES", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 200, "end" : 395, "hmmStart" : 26, "hmmEnd" : 124, "hmmLength" : 134, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 30, "envelopeEnd" : 480, "location-fragments" : [ { "start" : 200, "end" : 395, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-19, "familyName" : "GLUCOSYL/GLUCURONOSYL TRANSFERASES", "score" : 71.7, "model-ac" : "PTHR11926" }, { "signature" : { "accession" : "SSF53756", "name" : "UDP-Glycosyltransferase/glycogen phosphorylase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 468, "hmmLength" : 471, "location-fragments" : [ { "start" : 25, "end" : 468, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.83E-103, "model-ac" : "0054711" }, { "signature" : { "accession" : "G3DSA:3.40.50.2000", "name" : "Glycogen Phosphorylase B;", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 176, "hmmStart" : 17, "hmmEnd" : 146, "hmmLength" : 261, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-9, "score" : 40.5, "envelopeStart" : 25, "envelopeEnd" : 176, "postProcessed" : true, "location-fragments" : [ { "start" : 25, "end" : 176, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-10, "score" : 42.7, "model-ac" : "2iyaA01" }, { "signature" : { "accession" : "G3DSA:3.40.50.2000", "name" : "Glycogen Phosphorylase B;", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 273, "end" : 443, "hmmStart" : 5, "hmmEnd" : 166, "hmmLength" : 170, "hmmBounds" : "COMPLETE", "evalue" : 8.6E-43, "score" : 147.7, "envelopeStart" : 273, "envelopeEnd" : 443, "postProcessed" : true, "location-fragments" : [ { "start" : 273, "end" : 443, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-43, "score" : 148.4, "model-ac" : "2o6lB00" }, { "signature" : { "accession" : "cd03784", "name" : "GT1_Gtf-like", "description" : "GT1_Gtf-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 27, "end" : 455, "sites" : [ { "description" : "homodimer interface", "numLocations" : 5, "siteLocations" : [ { "start" : 137, "end" : 137, "residue" : "S" }, { "start" : 49, "end" : 49, "residue" : "R" }, { "start" : 450, "end" : 450, "residue" : "D" }, { "start" : 453, "end" : 453, "residue" : "V" }, { "start" : 449, "end" : 449, "residue" : "L" } ] }, { "description" : "active site", "numLocations" : 14, "siteLocations" : [ { "start" : 369, "end" : 369, "residue" : "G" }, { "start" : 375, "end" : 375, "residue" : "E" }, { "start" : 367, "end" : 367, "residue" : "H" }, { "start" : 372, "end" : 372, "residue" : "S" }, { "start" : 34, "end" : 34, "residue" : "S" }, { "start" : 37, "end" : 37, "residue" : "G" }, { "start" : 196, "end" : 196, "residue" : "L" }, { "start" : 35, "end" : 35, "residue" : "H" }, { "start" : 188, "end" : 188, "residue" : "D" }, { "start" : 300, "end" : 300, "residue" : "S" }, { "start" : 371, "end" : 371, "residue" : "N" }, { "start" : 191, "end" : 191, "residue" : "S" }, { "start" : 243, "end" : 243, "residue" : "I" }, { "start" : 192, "end" : 192, "residue" : "F" } ] }, { "description" : "acceptor substrate-binding pocket", "numLocations" : 1, "siteLocations" : [ { "start" : 35, "end" : 35, "residue" : "H" } ] }, { "description" : "TDP-binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 369, "end" : 369, "residue" : "G" }, { "start" : 300, "end" : 300, "residue" : "S" }, { "start" : 367, "end" : 367, "residue" : "H" }, { "start" : 372, "end" : 372, "residue" : "S" }, { "start" : 371, "end" : 371, "residue" : "N" }, { "start" : 34, "end" : 34, "residue" : "S" } ] } ], "evalue" : 1.56276E-59, "score" : 200.085, "location-fragments" : [ { "start" : 27, "end" : 455, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd03784" }, { "signature" : { "accession" : "PF00201", "name" : "UDPGT", "description" : "UDP-glucoronosyl and UDP-glucosyl transferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002213", "name" : "UDP_glucos_trans", "description" : "UDP-glucuronosyl/UDP-glucosyltransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "UDP-glycosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008194" } ], "pathwayXRefs" : [ { "name" : "Glucuronidation", "databaseName" : "Reactome", "id" : "R-HSA-156588" } ] } }, "locations" : [ { "start" : 33, "end" : 508, "hmmStart" : 10, "hmmEnd" : 489, "hmmLength" : 499, "hmmBounds" : "INCOMPLETE", "evalue" : 4.0E-86, "score" : 289.8, "envelopeStart" : 25, "envelopeEnd" : 520, "postProcessed" : true, "location-fragments" : [ { "start" : 33, "end" : 508, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-86, "score" : 290.8, "model-ac" : "PF00201" } ], "xref" : [ { "name" : "XP_018910301.1 PREDICTED: UDP-glucuronosyltransferase 2B20-like [Bemisia tabaci]", "id" : "XP_018910301.1" }, { "name" : "XP_018910303.1 PREDICTED: UDP-glucuronosyltransferase 2B20-like [Bemisia tabaci]", "id" : "XP_018910303.1" } ] },{ "sequence" : "MYLLTCPNYYKSGRRAAGHFTSVSTCVRGPPLGRATAPVSQPPSRYIYLLHSTMPAIINNKGPYIAVIEEGTRTVKFVLFSAETQEEVVSYSVDVPGESPQEGWAEQDPNTLLSAVHLCIEETMPQLATIGASSKDIVALGITNQRETTIVWDSITGEPLYNAILWSDMRADVTVDEVLAKFPDNNKDYLKPLSGLPVSPYFSALKLKWLIDNVPSVRKAIREHRCLFGTVDSWLIWNLTGGKDGGLHITDVTNASRTMLMNIDSLQWDPLLCKHFHIPMEILPEIRSSSEIYGLVKGHMLDGVPISGILGNQQAALVGQRCFKEGQAKNTYRSGCFLLYNTGNNRVHSSQGLVTTVAFQHGRDKRPVYALEGSVAVAGTALKWLRDNLNMMKDNEEAEDLAEAVKTTGDVYFVPAFAGLYAPYWRKDARGILCGLTQFTTKGHIIRAALEAVCYQTRDILEAMHRDCGFPLSTLHVDGQMTTNRLLMQLQADISGIPVQRNNKKDITALGVAYMAASAAGIDVWDLENLSANSGSDASLEDTFLPSISHEERNLRYTKWKMAVHRSLGWAMPKKSDVMTDERYRLLSSIPASLFILGSFVMLTLSEKVLA", "md5" : "6c94854b83bb08012cfe826a15243d86", "matches" : [ { "signature" : { "accession" : "TIGR01311", "name" : "TIGR01311", "description" : "glycerol_kin: glycerol kinase", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR005999", "name" : "Glycerol_kin", "description" : "Glycerol kinase", "type" : "FAMILY", "goXRefs" : [ { "name" : "glycerol-3-phosphate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006072" }, { "name" : "glycerol kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004370" } ], "pathwayXRefs" : [ { "name" : "Glycerol degradation I", "databaseName" : "MetaCyc", "id" : "PWY-4261" }, { "name" : "Triglyceride biosynthesis", "databaseName" : "Reactome", "id" : "R-HSA-75109" }, { "name" : "Glycerolipid metabolism", "databaseName" : "KEGG", "id" : "00561+2.7.1.30" } ] } }, "locations" : [ { "start" : 63, "end" : 570, "hmmStart" : 1, "hmmEnd" : 496, "hmmLength" : 496, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-199, "score" : 661.7, "envelopeStart" : 63, "envelopeEnd" : 570, "postProcessed" : false, "location-fragments" : [ { "start" : 63, "end" : 570, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-199, "score" : 661.9, "model-ac" : "TIGR01311" }, { "signature" : { "accession" : "PF00370", "name" : "FGGY_N", "description" : "FGGY family of carbohydrate kinases, N-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018484", "name" : "Carb_kinase_FGGY_N", "description" : "Carbohydrate kinase, FGGY, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 64, "end" : 319, "hmmStart" : 1, "hmmEnd" : 245, "hmmLength" : 245, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-66, "score" : 224.5, "envelopeStart" : 64, "envelopeEnd" : 319, "postProcessed" : true, "location-fragments" : [ { "start" : 64, "end" : 319, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.5E-67, "score" : 225.3, "model-ac" : "PF00370" }, { "signature" : { "accession" : "PS00933", "name" : "FGGY_KINASES_1", "description" : "FGGY family of carbohydrate kinases signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018483", "name" : "Carb_kinase_FGGY_CS", "description" : "Carbohydrate kinase, FGGY, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Glycerol degradation I", "databaseName" : "MetaCyc", "id" : "PWY-4261" }, { "name" : "Glycerolipid metabolism", "databaseName" : "KEGG", "id" : "00561+2.7.1.30" } ] } }, "locations" : [ { "start" : 201, "end" : 213, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I8M", "alignment" : "YfSalKLKWLIDN", "location-fragments" : [ { "start" : 201, "end" : 213, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00933" }, { "signature" : { "accession" : "PF02782", "name" : "FGGY_C", "description" : "FGGY family of carbohydrate kinases, C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018485", "name" : "Carb_kinase_FGGY_C", "description" : "Carbohydrate kinase, FGGY, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 328, "end" : 519, "hmmStart" : 1, "hmmEnd" : 197, "hmmLength" : 198, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 7.3E-61, "score" : 205.4, "envelopeStart" : 328, "envelopeEnd" : 520, "postProcessed" : true, "location-fragments" : [ { "start" : 328, "end" : 519, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-61, "score" : 206.4, "model-ac" : "PF02782" }, { "signature" : { "accession" : "SSF53067", "name" : "Actin-like ATPase domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR043129", "name" : "ATPase_NBD", "description" : "ATPase, nucleotide binding domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 322, "end" : 571, "hmmLength" : 246, "location-fragments" : [ { "start" : 322, "end" : 571, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.55E-69, "model-ac" : "0035709" }, { "signature" : { "accession" : "G3DSA:3.30.420.40", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 58, "end" : 320, "hmmStart" : 9, "hmmEnd" : 267, "hmmLength" : 268, "hmmBounds" : "COMPLETE", "evalue" : 6.1E-91, "score" : 306.4, "envelopeStart" : 58, "envelopeEnd" : 320, "postProcessed" : true, "location-fragments" : [ { "start" : 58, "end" : 320, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-92, "score" : 309.6, "model-ac" : "3wxlA01" }, { "signature" : { "accession" : "G3DSA:3.30.420.40", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 321, "end" : 572, "hmmStart" : 2, "hmmEnd" : 244, "hmmLength" : 247, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-81, "score" : 275.4, "envelopeStart" : 321, "envelopeEnd" : 572, "postProcessed" : true, "location-fragments" : [ { "start" : 321, "end" : 572, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.1E-82, "score" : 276.0, "model-ac" : "3ezwD02" }, { "signature" : { "accession" : "PTHR10196:SF40", "name" : "FI03690P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 63, "end" : 584, "hmmStart" : 8, "hmmEnd" : 529, "hmmLength" : 558, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 52, "envelopeEnd" : 607, "location-fragments" : [ { "start" : 63, "end" : 584, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-255, "familyName" : "FI03690P", "score" : 851.8, "model-ac" : "PTHR10196:SF40" }, { "signature" : { "accession" : "PTHR10196", "name" : "SUGAR KINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 63, "end" : 584, "hmmStart" : 8, "hmmEnd" : 529, "hmmLength" : 558, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 52, "envelopeEnd" : 607, "location-fragments" : [ { "start" : 63, "end" : 584, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-255, "familyName" : "FI03690P", "score" : 851.8, "model-ac" : "PTHR10196" }, { "signature" : { "accession" : "SSF53067", "name" : "Actin-like ATPase domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR043129", "name" : "ATPase_NBD", "description" : "ATPase, nucleotide binding domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 64, "end" : 322, "hmmLength" : 252, "location-fragments" : [ { "start" : 64, "end" : 322, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-70, "model-ac" : "0049108" }, { "signature" : { "accession" : "PS00445", "name" : "FGGY_KINASES_2", "description" : "FGGY family of carbohydrate kinases signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018483", "name" : "Carb_kinase_FGGY_CS", "description" : "Carbohydrate kinase, FGGY, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Glycerol degradation I", "databaseName" : "MetaCyc", "id" : "PWY-4261" }, { "name" : "Glycerolipid metabolism", "databaseName" : "KEGG", "id" : "00561+2.7.1.30" } ] } }, "locations" : [ { "start" : 431, "end" : 451, "level" : "STRONG", "cigarAlignment" : "1M1I4M7I8M", "alignment" : "GiLCGLtqfttkgHIIRAALE", "location-fragments" : [ { "start" : 431, "end" : 451, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00445" } ], "xref" : [ { "name" : "XP_018909614.1 PREDICTED: glycerol kinase-like isoform X3 [Bemisia tabaci]", "id" : "XP_018909614.1" } ] },{ "sequence" : "MGLILSASAVYVGVVEFLSVIDRIQRSIKFANEHKIESEAVEKLPYSQIEQDSAEVLNQNPVEFERLAEITYHKSNVSFEEDKSNYVTTDAVAALENSCTSGPMPAEGELTFESKSETYVSEETDCEIDSHKSSHTNKNSNSKCPESVEIVVKNENQNQIRDENENNMEIKKIPVDLSEDLSKINSAVSLEQLESTSELSSICDVGGSQNEMQTADSKERASDEIENRSVAINESMEKELGANLAILEENKFTSGVTDENAEVLMEDIKNDINNTFHDDLPQSENIPQCRMIHVKESTTDDKPRENDVQDEIPKREGNLREAEGNIEHGNGCDVGRENGSDIGGGVDVSIDSESHFARGSENFKTDRESSTTNSRFQENENVCSEIDANLIEQYRTDQCQNEQEGVASRVDGCSNGVNVLTDTIFEENSEGKHLEEGTIADKISTGSLKPQQALKVSTIKDEICSETSNQSSEANESINSSNSDEGQSDSINSKDDINNERATSQSEQRVNDSIDDNSTSDSVIDNVPNTQVSSQLVSDQIHTNICNDFGSVSVNNKNNSVHSFESDKDSCDAILDANNEEIVNKFPESVENNSNNLSGIGKSADDRFIDPHSHFIDDSFNSVDESCDHNKTNVDTDDHSTESSLLPLESNSCQNAPNTASNSVRYPESSNSSDSAAVKSSRESQEISKDSTSCSRSDSQISVVRPPENEGYETQPISYSKNERQRTSSPSEATFLSTNDRSIPGSPLFQGPAPRTICENDISESISPKKTFEDDCSSNAAQEPSDAQSENQQESRSRLAACFPFLPSLALGYRNTESTCLESERPKQITRYLRDE", "md5" : "78fce12a5d7a0d3fa699d8b76316b7b3", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 465, "end" : 531, "location-fragments" : [ { "start" : 465, "end" : 531, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 465, "end" : 488, "location-fragments" : [ { "start" : 465, "end" : 488, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 772, "end" : 797, "location-fragments" : [ { "start" : 772, "end" : 797, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 629, "end" : 797, "location-fragments" : [ { "start" : 629, "end" : 797, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 503, "end" : 531, "location-fragments" : [ { "start" : 503, "end" : 531, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 208, "end" : 229, "location-fragments" : [ { "start" : 208, "end" : 229, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 639, "end" : 704, "location-fragments" : [ { "start" : 639, "end" : 704, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 713, "end" : 745, "location-fragments" : [ { "start" : 713, "end" : 745, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910456.1 PREDICTED: TNF receptor-associated factor family protein DDB_G0272098-like [Bemisia tabaci]", "id" : "XP_018910456.1" } ] },{ "sequence" : "MKIEEEEKVEVTLLYFHSFFVHLRLVVVILIRRMKKSNNYFNGLIPKGSPGDLHSMRVEKVKENLRKMYNVKQAPYAVISGMILNGKSDDLIIMEIVRYLAPAPPPLPAIGPPGYPASAPPPVPAIGPPGYPAYHQLYGHQYGASQSWAGPPMQNDAFREAIAYEMEKFKKEERMKAEEKERLERKERDRKERDRKERERERRDKERKLEEQRVREREERKARGEQEKKAKEEEEKKKAKEEEEKKKAKEEEEKKKAKEEEEKKKEKEGGSKAKRRKKVSQTFFSLEYFSCHNDE", "md5" : "7774cfb88938ba3441b246fb31910563", "matches" : [ { "signature" : { "accession" : "PTHR31780:SF1", "name" : "STRESS RESPONSE PROTEIN NST1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 165, "end" : 271, "hmmStart" : 575, "hmmEnd" : 686, "hmmLength" : 1370, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 285, "location-fragments" : [ { "start" : 165, "end" : 271, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-14, "familyName" : "STRESS RESPONSE PROTEIN NST1", "score" : 52.6, "model-ac" : "PTHR31780:SF1" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 195, "end" : 275, "location-fragments" : [ { "start" : 195, "end" : 275, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 166, "end" : 270, "location-fragments" : [ { "start" : 166, "end" : 270, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR31780", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 165, "end" : 271, "hmmStart" : 575, "hmmEnd" : 686, "hmmLength" : 1370, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 285, "location-fragments" : [ { "start" : 165, "end" : 271, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-14, "familyName" : "STRESS RESPONSE PROTEIN NST1", "score" : 52.6, "model-ac" : "PTHR31780" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 195, "end" : 282, "location-fragments" : [ { "start" : 195, "end" : 282, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910141.1 PREDICTED: ensconsin-like [Bemisia tabaci]", "id" : "XP_018910141.1" } ] },{ "sequence" : "MKWRKECRFCKPSWSRAPALCAIILCVGTFVIFSITTRGYSDPNKAVLGWEPSKNLSVAAFLETVDVNGRREDSENGSVCDSELLLLVVVCSSPEKEALRTAIRQTWASLQDQSVRVVFLLGHPLPSHESAYVQSRISREKEMYQDIIQEDFIDSYNNLTIKSIMMLRWFTKNCERTSYLLKTDDDIFLDFRVLNQSLRRPFPKWIAPDNFLGGTLIRGASPNKDNNDKWFMPNYLYAGSKYPNYLSGTAYLMSRQVAEKLFTASFGVNMIHMEDIYITGLCARKAGVRPFSLFGFTLSKVKRMGCKSRHIMSHRVTPADMYRIWNTRAACSEFYVTSIFQDRQFGLWEKVANKLHGGR", "md5" : "ee934c7b10bdab1cd95ee73ec11460f4", "matches" : [ { "signature" : { "accession" : "PF01762", "name" : "Galactosyl_T", "description" : "Galactosyltransferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002659", "name" : "Glyco_trans_31", "description" : "Glycosyl transferase, family 31", "type" : "FAMILY", "goXRefs" : [ { "name" : "protein glycosylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006486" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 100, "end" : 290, "hmmStart" : 3, "hmmEnd" : 191, "hmmLength" : 195, "hmmBounds" : "INCOMPLETE", "evalue" : 2.4E-45, "score" : 154.8, "envelopeStart" : 98, "envelopeEnd" : 293, "postProcessed" : true, "location-fragments" : [ { "start" : 100, "end" : 290, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-45, "score" : 155.2, "model-ac" : "PF01762" }, { "signature" : { "accession" : "PTHR11214:SF148", "name" : "HEXOSYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 76, "end" : 318, "hmmStart" : 74, "hmmEnd" : 297, "hmmLength" : 303, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 36, "envelopeEnd" : 336, "location-fragments" : [ { "start" : 76, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.7E-67, "familyName" : "HEXOSYLTRANSFERASE", "score" : 228.0, "model-ac" : "PTHR11214:SF148" }, { "signature" : { "accession" : "PTHR11214", "name" : "BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR002659", "name" : "Glyco_trans_31", "description" : "Glycosyl transferase, family 31", "type" : "FAMILY", "goXRefs" : [ { "name" : "protein glycosylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006486" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 76, "end" : 318, "hmmStart" : 74, "hmmEnd" : 297, "hmmLength" : 303, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 36, "envelopeEnd" : 336, "location-fragments" : [ { "start" : 76, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.7E-67, "familyName" : "HEXOSYLTRANSFERASE", "score" : 228.0, "model-ac" : "PTHR11214" } ], "xref" : [ { "name" : "XP_018910332.1 PREDICTED: beta-1,3-galactosyltransferase 1-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910332.1" } ] },{ "sequence" : "MFLFRSTQHCARYLSSTAHLKHAAKMGTKVESPMGELAGKPLYLDAQATTPLDPRVLDAMLPFMTSAYGNPHSRTHAYGWESEKAVENAREEVASLIGCDPKEIIFTSGATESNNIAVKGVARFYASKKKHIITTQTEHKCVLDSCRVLEGEGFSITYLPVGTNGIIDLEELEKAITPQTSLVSIMTVNNEIGVKQPILEIGAICKAKKVFFHTDAAQAIGKLEIDVSQQNIDLMSISGHKVYGPKGIGALYVRRRPRVRVEPIQSGGGQERGMRSGTVPTPLVVGLGEACRIAKKEMKYDHAWMEKLSQRLLDRIFSSLTHVVRNGDPVHSYPGCVNLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGADEDLAHSSIRFGFGRFTTLEEVDYTAERCIKDVERLRNMSPLWEMVQEGIDLKSIKWTQH", "md5" : "4beeb23e714db745b734382129bd2080", "matches" : [ { "signature" : { "accession" : "TIGR02006", "name" : "TIGR02006", "description" : "IscS: cysteine desulfurase IscS", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR010240", "name" : "Cys_deSase_IscS", "description" : "Cysteine desulfurase IscS", "type" : "FAMILY", "goXRefs" : [ { "name" : "pyridoxal phosphate binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030170" }, { "name" : "[2Fe-2S] cluster assembly", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0044571" }, { "name" : "cysteine desulfurase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0031071" } ], "pathwayXRefs" : [ { "name" : "[2Fe-2S] iron-sulfur cluster biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-7250" }, { "name" : "Molybdenum cofactor biosynthesis", "databaseName" : "Reactome", "id" : "R-HSA-947581" }, { "name" : "Thiamine metabolism", "databaseName" : "KEGG", "id" : "00730+2.8.1.7" }, { "name" : "Mitochondrial iron-sulfur cluster biogenesis", "databaseName" : "Reactome", "id" : "R-HSA-1362409" } ] } }, "locations" : [ { "start" : 40, "end" : 440, "hmmStart" : 3, "hmmEnd" : 402, "hmmLength" : 402, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.7E-199, "score" : 660.2, "envelopeStart" : 38, "envelopeEnd" : 440, "postProcessed" : false, "location-fragments" : [ { "start" : 40, "end" : 440, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-199, "score" : 660.4, "model-ac" : "TIGR02006" }, { "signature" : { "accession" : "PS00595", "name" : "AA_TRANSFER_CLASS_5", "description" : "Aminotransferases class-V pyridoxal-phosphate attachment site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR020578", "name" : "Aminotrans_V_PyrdxlP_BS", "description" : "Aminotransferase class-V, pyridoxal-phosphate binding site", "type" : "BINDING_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 232, "end" : 251, "level" : "STRONG", "cigarAlignment" : "4M2I4M5I1M1I1M1I1M", "alignment" : "IDLMsiSGHKvygpkGiGaL", "location-fragments" : [ { "start" : 232, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00595" }, { "signature" : { "accession" : "G3DSA:3.40.640.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015421", "name" : "PyrdxlP-dep_Trfase_major", "description" : "Pyridoxal phosphate-dependent transferase, major domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 53, "end" : 297, "hmmStart" : 2, "hmmEnd" : 364, "hmmLength" : 368, "hmmBounds" : "INCOMPLETE", "evalue" : 2.2E-155, "score" : 519.3, "envelopeStart" : 42, "envelopeEnd" : 413, "postProcessed" : true, "location-fragments" : [ { "start" : 53, "end" : 297, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-155, "score" : 519.5, "model-ac" : "3lvmB02" }, { "signature" : { "accession" : "PF00266", "name" : "Aminotran_5", "description" : "Aminotransferase class-V", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000192", "name" : "Aminotrans_V_dom", "description" : "Aminotransferase class V domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 43, "end" : 404, "hmmStart" : 2, "hmmEnd" : 370, "hmmLength" : 371, "hmmBounds" : "INCOMPLETE", "evalue" : 2.3E-90, "score" : 303.2, "envelopeStart" : 42, "envelopeEnd" : 405, "postProcessed" : true, "location-fragments" : [ { "start" : 43, "end" : 404, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-90, "score" : 303.5, "model-ac" : "PF00266" }, { "signature" : { "accession" : "MF_00331", "name" : "Cys_desulf_IscS", "description" : "Cysteine desulfurase IscS [iscS].", "signatureLibraryRelease" : { "library" : "HAMAP", "version" : "2020_01" }, "entry" : { "accession" : "IPR010240", "name" : "Cys_deSase_IscS", "description" : "Cysteine desulfurase IscS", "type" : "FAMILY", "goXRefs" : [ { "name" : "pyridoxal phosphate binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030170" }, { "name" : "[2Fe-2S] cluster assembly", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0044571" }, { "name" : "cysteine desulfurase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0031071" } ], "pathwayXRefs" : [ { "name" : "[2Fe-2S] iron-sulfur cluster biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-7250" }, { "name" : "Molybdenum cofactor biosynthesis", "databaseName" : "Reactome", "id" : "R-HSA-947581" }, { "name" : "Thiamine metabolism", "databaseName" : "KEGG", "id" : "00730+2.8.1.7" }, { "name" : "Mitochondrial iron-sulfur cluster biogenesis", "databaseName" : "Reactome", "id" : "R-HSA-1362409" } ] } }, "locations" : [ { "start" : 38, "end" : 431, "score" : 51.818, "alignment" : "AGKPLYLDAQATTPLDPRVLDAMLPFMTSAYGNPHSrTHAYGWESEKAVENAREEVASLIGCDPKEIIFTSGATESNNIAVKGVARFYASKKKHIITTQTEHKCVLDSCRVLEGEGFSITYLPVGTNGIIDLEELEKAITPQTSLVSIMTVNNEIGVKQPILEIGAICKAKKVFFHTDAAQAIGKLEIDVSQQNIDLMSISGHKVYGPKGIGALYVRRRprVRVEPIQSGGGQERGMRSGTVPTPLVVGLGEACRIAKKEMKYDHAWMEKLSQRLLDRIFSSLTHVVRNGDPVHSYPGCVNLSFAYVEGES--LLMALKDVALSSGSACTSASLEPSYVLRAIGADEDLAHSSIRFGFGRFTTLEEVDYTAERCIKDVERLRNMSPLWEMVQEGID", "location-fragments" : [ { "start" : 38, "end" : 431, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "MF_00331" }, { "signature" : { "accession" : "PIRSF005572", "name" : "NifS", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR016454", "name" : "Cysteine_dSase", "description" : "Cysteine desulfurase", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Thiamine metabolism", "databaseName" : "KEGG", "id" : "00730+2.8.1.7" }, { "name" : "[2Fe-2S] iron-sulfur cluster biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-7250" } ] } }, "locations" : [ { "start" : 40, "end" : 420, "hmmStart" : 42, "hmmEnd" : 416, "hmmLength" : 382, "hmmBounds" : "INCOMPLETE", "evalue" : 1.5E-129, "score" : 428.1, "envelopeStart" : 40, "envelopeEnd" : 420, "postProcessed" : false, "location-fragments" : [ { "start" : 40, "end" : 420, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-129, "score" : 428.4, "model-ac" : "PIRSF005572" }, { "signature" : { "accession" : "SSF53383", "name" : "PLP-dependent transferases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR015424", "name" : "PyrdxlP-dep_Trfase", "description" : "Pyridoxal phosphate-dependent transferase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 41, "end" : 427, "hmmLength" : 391, "location-fragments" : [ { "start" : 41, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.99E-105, "model-ac" : "0042144" }, { "signature" : { "accession" : "PTHR11601", "name" : "CYSTEINE DESULFURYLASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 17, "end" : 440, "hmmStart" : 34, "hmmEnd" : 457, "hmmLength" : 457, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 4, "envelopeEnd" : 440, "location-fragments" : [ { "start" : 17, "end" : 440, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-243, "familyName" : "CYSTEINE DESULFURASE, MITOCHONDRIAL", "score" : 811.5, "model-ac" : "PTHR11601" }, { "signature" : { "accession" : "G3DSA:3.90.1150.10", "name" : "Aspartate Aminotransferase", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015422", "name" : "PyrdxlP-dep_Trfase_dom1", "description" : "Pyridoxal phosphate-dependent transferase domain 1", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 43, "end" : 409, "hmmStart" : 2, "hmmEnd" : 364, "hmmLength" : 176, "hmmBounds" : "INCOMPLETE", "evalue" : 2.2E-155, "score" : 519.3, "envelopeStart" : 42, "envelopeEnd" : 413, "postProcessed" : true, "location-fragments" : [ { "start" : 298, "end" : 409, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 43, "end" : 52, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.9E-155, "score" : 519.5, "model-ac" : "3lvmB01" }, { "signature" : { "accession" : "PTHR11601:SF34", "name" : "CYSTEINE DESULFURASE, MITOCHONDRIAL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR010240", "name" : "Cys_deSase_IscS", "description" : "Cysteine desulfurase IscS", "type" : "FAMILY", "goXRefs" : [ { "name" : "pyridoxal phosphate binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030170" }, { "name" : "[2Fe-2S] cluster assembly", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0044571" }, { "name" : "cysteine desulfurase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0031071" } ], "pathwayXRefs" : [ { "name" : "[2Fe-2S] iron-sulfur cluster biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-7250" }, { "name" : "Molybdenum cofactor biosynthesis", "databaseName" : "Reactome", "id" : "R-HSA-947581" }, { "name" : "Thiamine metabolism", "databaseName" : "KEGG", "id" : "00730+2.8.1.7" }, { "name" : "Mitochondrial iron-sulfur cluster biogenesis", "databaseName" : "Reactome", "id" : "R-HSA-1362409" } ] } }, "locations" : [ { "start" : 17, "end" : 440, "hmmStart" : 34, "hmmEnd" : 457, "hmmLength" : 457, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 4, "envelopeEnd" : 440, "location-fragments" : [ { "start" : 17, "end" : 440, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-243, "familyName" : "CYSTEINE DESULFURASE, MITOCHONDRIAL", "score" : 811.5, "model-ac" : "PTHR11601:SF34" } ], "xref" : [ { "name" : "XP_018909790.1 PREDICTED: cysteine desulfurase, mitochondrial [Bemisia tabaci]", "id" : "XP_018909790.1" } ] },{ "sequence" : "MCSLLEPSASMAPVLLVVFLATAFHQTDTLQVCMTSGDARVGRSDVREVLRGQIDPSFWPTRGRRGGSSEESEPPFWANRGREFQSEEEQPPFWGNRGRTLDQDPDTHHHSRPPVEALLAVDRDPEALIPHIQKWFNVRKRQQRLASCCDTPFSANYSMYVEEPQHILLERRGGSEEKDDQFWVSRGRREATEKRESNLERLNREFSPLYEDAEEGPSVQKRSEPPPAPKVEDPNAEDAKFWKSLASTIGAKRARPSNASDAEPQQ", "md5" : "e76e2c5255de9af25c94b79647a14fa3", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 194, "end" : 219, "location-fragments" : [ { "start" : 194, "end" : 219, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 57, "end" : 113, "location-fragments" : [ { "start" : 57, "end" : 113, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 251, "end" : 266, "location-fragments" : [ { "start" : 251, "end" : 266, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 194, "end" : 266, "location-fragments" : [ { "start" : 194, "end" : 266, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910152.1 PREDICTED: uncharacterized protein LOC109039214 isoform X1 [Bemisia tabaci]", "id" : "XP_018910152.1" } ] },{ "sequence" : "MSTNDNALHDAFAEIYAAKAEKIIINTTDFEVVTHSSGYIDKTPLILDLLPLPSHIVIHGPRGFSKSTNLNMLKTFFEHELGENHLAKDPQKTHKLGLFRDKSIFSNGTQFWKHFARYPVIYLDLGSVKTKTFHDFTTSFIEHCVHPLMEKFSYLLNNTNIWESSALKTVSFSKSYKWKKEELIKFGVNLAELVRRHHDTKSILLIDDYDHPVISAVLDTHVSQDDTINIIEFMGAFVNAMTKHSDHIYRSVLTGTIAVTLEYDMDTSSSNVEYYSIFDARIFYNAYGLTGDDLKVLQKQLHVPPSQMELTRSYYQGYNVFDNRFAADTGLYIRWAPVAPKTKIYNTYSVLASLKNVDLKPWWPSGEVPLIPLITADKYATDFEECMLRSCSIDVETYISRFDLLQLKKSLLTPEKPTVTSDIILAFLFQSGYFTPLERNGDERTITAPNYEVQTKMIESFYRTAYLYKRYNYTKEDEKQYVTAMDKLNSTISTFQDVVKSVRNLFRSEAPLGEKFMQAVLLYPLVNSDKFYAYRIEKHDDPFLRYDAVAERRRDNAAIVVTLRCRPQDLKRAVGQIVKAPVGNKFDLLPNRKDKIDLRFIITQDKEVYGYFNYTTSKGDSTSELWPTLKHY", "md5" : "d6d7ff88ec0502c7cdb006ce703ee168", "matches" : [ { "signature" : { "accession" : "PF09820", "name" : "AAA-ATPase_like", "description" : "Predicted AAA-ATPase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018631", "name" : "AAA-ATPase-like_dom", "description" : "AAA-ATPase-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 28, "end" : 320, "hmmStart" : 5, "hmmEnd" : 259, "hmmLength" : 279, "hmmBounds" : "INCOMPLETE", "evalue" : 3.4E-24, "score" : 85.7, "envelopeStart" : 25, "envelopeEnd" : 356, "postProcessed" : true, "location-fragments" : [ { "start" : 28, "end" : 320, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-24, "score" : 86.9, "model-ac" : "PF09820" }, { "signature" : { "accession" : "PTHR34825", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 20, "end" : 588, "hmmStart" : 26, "hmmEnd" : 580, "hmmLength" : 590, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 9, "envelopeEnd" : 597, "location-fragments" : [ { "start" : 20, "end" : 588, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-67, "familyName" : "FAMILY NOT NAMED", "score" : 231.3, "model-ac" : "PTHR34825" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 47, "end" : 213, "hmmLength" : 283, "location-fragments" : [ { "start" : 47, "end" : 73, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 112, "end" : 213, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 2.63E-6, "model-ac" : "0052726" } ], "xref" : [ { "name" : "XP_018909809.1 PREDICTED: uncharacterized protein LOC109038977 isoform X3 [Bemisia tabaci]", "id" : "XP_018909809.1" }, { "name" : "XP_018909810.1 PREDICTED: uncharacterized protein LOC109038977 isoform X3 [Bemisia tabaci]", "id" : "XP_018909810.1" } ] },{ "sequence" : "MDGENVNSNGVSETDARGDKAAGAAMFPQNGRGETKTEVTSASRGCSFCGWRFVWEGRLIKCYKDTAETVTARMASDRDAWYYNMNHKNRGIAIIFNHENFTNPKLKTRCGTKTDCENLASTLRSLRFEVYTYFDASYSKVMSVISEVRNMDHSDNDCFLMAVLSHGEQNIIHAYDSPYQPEDLWHPFTADKCPSLAGKPKLFFIQACQGDRLDPGVTLMKRTETDSGPMSYRIPVHADFLIAYSTIPERRKVRTRLGRILAFFSCKERRRSRLRHQQCCYTLTPDEGTENMMTEDQCCQGFYSWRNTQRGSWFMQALCEELKKHCYSLDLLTILTFVNRRVATDYQSNVPGNNEMDAQKQIPCITYMLTRLLKFKPK", "md5" : "aa5e187706a6594e9f540d1c6d4152ce", "matches" : [ { "signature" : { "accession" : "PS50208", "name" : "CASPASE_P20", "description" : "Caspase family p20 domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001309", "name" : "Pept_C14_p20", "description" : "Peptidase C14, p20 domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "cysteine-type endopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004197" }, { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 89, "end" : 212, "score" : 39.066, "alignment" : "NRGIAIIFNHENFTnpKLKTRCGTKTDCENLASTLRSLRFEVYTYFDASYSKVMSVISEVRNMDHSDNDCFLMAVLSHGEQNIIHAYDS-PYQPEDLWHPFTADKCPSLAGKPKLFFIQACQGDR", "location-fragments" : [ { "start" : 89, "end" : 212, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50208" }, { "signature" : { "accession" : "PS50207", "name" : "CASPASE_P10", "description" : "Caspase family p10 domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002138", "name" : "Pept_C14_p10", "description" : "Peptidase C14, caspase non-catalytic subunit p10", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type endopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004197" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 298, "end" : 377, "score" : 26.57, "alignment" : "----------------CCQGFYSWRNTQRGSWFMQALCEELKKHCYSLDLLTILTFVNRRVAtdyqSNVPGNNEMDAQKQIPCITYMLTRLLKFKP", "location-fragments" : [ { "start" : 298, "end" : 377, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50207" }, { "signature" : { "accession" : "PS01122", "name" : "CASPASE_CYS", "description" : "Caspase family cysteine active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR033139", "name" : "Caspase_cys_AS", "description" : "Peptidase family C14A, cysteine active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 199, "end" : 210, "level" : "STRONG", "cigarAlignment" : "12M", "alignment" : "KPKLFFIQACQG", "location-fragments" : [ { "start" : 199, "end" : 210, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01122" }, { "signature" : { "accession" : "SSF52129", "name" : "Caspase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029030", "name" : "Caspase-like_dom_sf", "description" : "Caspase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 74, "end" : 251, "hmmLength" : 256, "location-fragments" : [ { "start" : 74, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.94E-59, "model-ac" : "0040830" }, { "signature" : { "accession" : "PTHR10454:SF216", "name" : "AT03047P-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 298, "end" : 377, "hmmStart" : 196, "hmmEnd" : 271, "hmmLength" : 272, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 288, "envelopeEnd" : 378, "location-fragments" : [ { "start" : 298, "end" : 377, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-96, "familyName" : "AT03047P-RELATED", "score" : 324.1, "model-ac" : "PTHR10454:SF216" }, { "signature" : { "accession" : "cd00032", "name" : "CASc", "description" : "CASc", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR015917", "name" : "Pept_C14A", "description" : "Peptidase C14A, caspase catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 82, "end" : 376, "sites" : [ { "description" : "substrate pocket", "numLocations" : 12, "siteLocations" : [ { "start" : 305, "end" : 305, "residue" : "W" }, { "start" : 313, "end" : 313, "residue" : "W" }, { "start" : 303, "end" : 303, "residue" : "Y" }, { "start" : 206, "end" : 206, "residue" : "Q" }, { "start" : 213, "end" : 213, "residue" : "L" }, { "start" : 167, "end" : 167, "residue" : "G" }, { "start" : 307, "end" : 307, "residue" : "N" }, { "start" : 308, "end" : 308, "residue" : "T" }, { "start" : 306, "end" : 306, "residue" : "R" }, { "start" : 304, "end" : 304, "residue" : "S" }, { "start" : 312, "end" : 312, "residue" : "S" }, { "start" : 109, "end" : 109, "residue" : "R" } ] }, { "description" : "active site", "numLocations" : 2, "siteLocations" : [ { "start" : 166, "end" : 166, "residue" : "H" }, { "start" : 208, "end" : 208, "residue" : "C" } ] }, { "description" : "proteolytic cleavage site", "numLocations" : 2, "siteLocations" : [ { "start" : 235, "end" : 235, "residue" : "P" }, { "start" : 215, "end" : 215, "residue" : "P" } ] }, { "description" : "dimer interface", "numLocations" : 15, "siteLocations" : [ { "start" : 244, "end" : 244, "residue" : "Y" }, { "start" : 247, "end" : 247, "residue" : "I" }, { "start" : 302, "end" : 302, "residue" : "F" }, { "start" : 236, "end" : 236, "residue" : "V" }, { "start" : 360, "end" : 360, "residue" : "K" }, { "start" : 365, "end" : 365, "residue" : "I" }, { "start" : 237, "end" : 237, "residue" : "H" }, { "start" : 372, "end" : 372, "residue" : "L" }, { "start" : 214, "end" : 214, "residue" : "D" }, { "start" : 366, "end" : 366, "residue" : "T" }, { "start" : 371, "end" : 371, "residue" : "R" }, { "start" : 368, "end" : 368, "residue" : "M" }, { "start" : 339, "end" : 339, "residue" : "N" }, { "start" : 325, "end" : 325, "residue" : "H" }, { "start" : 333, "end" : 333, "residue" : "T" } ] } ], "evalue" : 5.17974E-93, "score" : 276.789, "location-fragments" : [ { "start" : 82, "end" : 376, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00032" }, { "signature" : { "accession" : "PF00656", "name" : "Peptidase_C14", "description" : "Caspase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 298, "end" : 374, "hmmStart" : 177, "hmmEnd" : 246, "hmmLength" : 247, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-10, "score" : 41.4, "envelopeStart" : 297, "envelopeEnd" : 375, "postProcessed" : true, "location-fragments" : [ { "start" : 298, "end" : 374, "dc-status" : "CONTINUOUS" } ] }, { "start" : 91, "end" : 249, "hmmStart" : 1, "hmmEnd" : 180, "hmmLength" : 247, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.5E-26, "score" : 93.2, "envelopeStart" : 91, "envelopeEnd" : 266, "postProcessed" : true, "location-fragments" : [ { "start" : 91, "end" : 249, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-39, "score" : 136.6, "model-ac" : "PF00656" }, { "signature" : { "accession" : "SM00115", "name" : "caspase_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR015917", "name" : "Pept_C14A", "description" : "Peptidase C14A, caspase catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 82, "end" : 377, "hmmStart" : 1, "hmmEnd" : 282, "hmmLength" : 282, "hmmBounds" : "COMPLETE", "evalue" : 9.6E-91, "score" : 317.4, "location-fragments" : [ { "start" : 82, "end" : 377, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.6E-91, "score" : 317.4, "model-ac" : "SM00115" }, { "signature" : { "accession" : "PTHR10454:SF216", "name" : "AT03047P-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 65, "end" : 254, "hmmStart" : 15, "hmmEnd" : 204, "hmmLength" : 272, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 34, "envelopeEnd" : 278, "location-fragments" : [ { "start" : 65, "end" : 254, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-96, "familyName" : "AT03047P-RELATED", "score" : 324.1, "model-ac" : "PTHR10454:SF216" }, { "signature" : { "accession" : "PS01121", "name" : "CASPASE_HIS", "description" : "Caspase family histidine active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR016129", "name" : "Caspase_his_AS", "description" : "Peptidase family C14A, His active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 153, "end" : 167, "level" : "STRONG", "cigarAlignment" : "1M4I1M2I1M1I5M", "alignment" : "HsdndCflMaVLSHG", "location-fragments" : [ { "start" : 153, "end" : 167, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01121" }, { "signature" : { "accession" : "PTHR10454", "name" : "CASPASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR002398", "name" : "Pept_C14", "description" : "Peptidase C14 family", "type" : "FAMILY", "goXRefs" : [ { "name" : "cysteine-type endopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004197" }, { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 298, "end" : 377, "hmmStart" : 196, "hmmEnd" : 271, "hmmLength" : 272, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 288, "envelopeEnd" : 378, "location-fragments" : [ { "start" : 298, "end" : 377, "dc-status" : "CONTINUOUS" } ] }, { "start" : 65, "end" : 254, "hmmStart" : 15, "hmmEnd" : 204, "hmmLength" : 272, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 34, "envelopeEnd" : 278, "location-fragments" : [ { "start" : 65, "end" : 254, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-96, "familyName" : "AT03047P-RELATED", "score" : 324.1, "model-ac" : "PTHR10454" }, { "signature" : { "accession" : "PR00376", "name" : "IL1BCENZYME", "description" : "Interleukin-1B converting enzyme signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR015917", "name" : "Pept_C14A", "description" : "Peptidase C14A, caspase catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 109, "end" : 127, "pvalue" : 1.56E-5, "score" : 34.61, "motifNumber" : 2, "location-fragments" : [ { "start" : 109, "end" : 127, "dc-status" : "CONTINUOUS" } ] }, { "start" : 127, "end" : 145, "pvalue" : 0.0294, "score" : 17.38, "motifNumber" : 3, "location-fragments" : [ { "start" : 127, "end" : 145, "dc-status" : "CONTINUOUS" } ] }, { "start" : 89, "end" : 102, "pvalue" : 3.72E-6, "score" : 39.83, "motifNumber" : 1, "location-fragments" : [ { "start" : 89, "end" : 102, "dc-status" : "CONTINUOUS" } ] }, { "start" : 159, "end" : 167, "pvalue" : 6.93E-4, "score" : 48.48, "motifNumber" : 4, "location-fragments" : [ { "start" : 159, "end" : 167, "dc-status" : "CONTINUOUS" } ] }, { "start" : 193, "end" : 211, "pvalue" : 1.27E-11, "score" : 68.26, "motifNumber" : 5, "location-fragments" : [ { "start" : 193, "end" : 211, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-20, "graphscan" : "IIiII..", "model-ac" : "PR00376" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 36, "location-fragments" : [ { "start" : 1, "end" : 36, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF52129", "name" : "Caspase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029030", "name" : "Caspase-like_dom_sf", "description" : "Caspase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 298, "end" : 377, "hmmLength" : 256, "location-fragments" : [ { "start" : 298, "end" : 377, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.29E-25, "model-ac" : "0040830" } ], "xref" : [ { "name" : "XP_018910198.1 PREDICTED: caspase-1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910198.1" } ] },{ "sequence" : "MTFLVVVVHAITSENILKSSLNTKNHEKWISRIFSDHIWNYNMTARYNPDCMQHFKIFRQHQANFSTWALQMLDASDLIPTGFLVGDGYRLGNFDECLQTNIPSELGFFPQYCLPTFTILQEEDTQNFAASSNDWRESIWKRLQAESRIKVPKNRFSLSFCIPSTCSPYDLQTSLQVLLHNVTRPLGYDLNVTVDDLHCTTGRDRPESAGYVIMRSFLVVATVVLIFCSVADIVLAAIQDGKYDLNNCSFTKASGVAKWLIPFSFYRNMSQLLAAPTSPDDYKILHGIKCVLLVMTIVGHRSMFVAERAAITNWSYFEKRFHEFSIFYVAMPIPDIFFSITGFLLCLSMLKQLENKTFNVWVHATNKFLRVMPAYMFVLAYFIFIFPHSGDGPLWKTTTAADLKYCHKNWWMNLLFINNYFNLGEWCLPHFYYIAADVHFFIVGSIIVFLCWRWKSLKWIILGSALILSALIPFTITYLNRYEGLVKIYADFYRNMRNHKMLTDVNMKSHNRFGGYMIGIAGAFWMRHLQAERRPLSKAGAWAGVFIGVIMIAAITIARHLLHLPTTEYNVTIHALFAGLNTQILCAGVITIAVIQITTDFGALDSLFLTQNIFPPISRLSFWAFLINIPLIMNRVGSYKTHIHITHEDMVYGGQYWGDVPLTYFLSLYCHLLIDAPISYIKPIILKYLSRKQLQVDKKE", "md5" : "35d97df9b804e84494b9044461c4c87d", "matches" : [ { "signature" : { "accession" : "PTHR11161", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 38, "end" : 690, "hmmStart" : 71, "hmmEnd" : 704, "hmmLength" : 730, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 700, "location-fragments" : [ { "start" : 38, "end" : 690, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-85, "familyName" : "FI22618P1-RELATED", "score" : 288.4, "model-ac" : "PTHR11161" }, { "signature" : { "accession" : "SM00703", "name" : "nrf", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006621", "name" : "Nose-resist-to-fluoxetine_N", "description" : "Nose resistant-to-fluoxetine protein, N-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 48, "end" : 201, "hmmStart" : 1, "hmmEnd" : 178, "hmmLength" : 178, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-4, "score" : 15.2, "location-fragments" : [ { "start" : 48, "end" : 201, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-4, "score" : 15.2, "model-ac" : "SM00703" }, { "signature" : { "accession" : "PF01757", "name" : "Acyl_transf_3", "description" : "Acyltransferase family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002656", "name" : "Acyl_transf_3", "description" : "Acyltransferase 3", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transferase activity, transferring acyl groups other than amino-acyl groups", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016747" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 285, "end" : 634, "hmmStart" : 4, "hmmEnd" : 306, "hmmLength" : 340, "hmmBounds" : "INCOMPLETE", "evalue" : 7.6E-9, "score" : 35.1, "envelopeStart" : 282, "envelopeEnd" : 674, "postProcessed" : true, "location-fragments" : [ { "start" : 285, "end" : 634, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-9, "score" : 35.9, "model-ac" : "PF01757" }, { "signature" : { "accession" : "PTHR11161:SF58", "name" : "FI22618P1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 38, "end" : 690, "hmmStart" : 71, "hmmEnd" : 704, "hmmLength" : 730, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 700, "location-fragments" : [ { "start" : 38, "end" : 690, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-85, "familyName" : "FI22618P1-RELATED", "score" : 288.4, "model-ac" : "PTHR11161:SF58" } ], "xref" : [ { "name" : "XP_018909774.1 PREDICTED: nose resistant to fluoxetine protein 6-like [Bemisia tabaci]", "id" : "XP_018909774.1" } ] },{ "sequence" : "MQRCAQLSDSSSDDDDNFEEVPSENSNYFSPGFHQSGGYDLPSPVKRRKPSQSTSSNPINDDESDNLSSISANCESDYGSVSGKRNHRSMSLMSEDSEKNFHDSTHDESIYGNSSLPKFYATPSERGRTISQDFSEKDESNDEGSTRTAQGYFSGASERVRTKSQELSEFESNEEDYMSSTSASDVDVKPSKRRSEDFPSYNPRTSFYGSNQSEGVSASKSYESNDEEADKLSATLANISKKQSSSPTKGIKMTENLYIPKTRFSKSSSCDTVQSSSTSDFSSFEGKRKSTDSEEEVNSGPPPKKSKSVAIKTSGAVSKMMEKMGYSSGKGLGKHAQGVVEPVALSSQRGRRGLGHIVEGFEEEDVEWDFDQEKVEVIENVDWLEYYGKDILQLKPPEDLTKRLLEKGLKEELEREKRKTLLGGVQKPCPKKMSLDDETNFCDPKLVKKVIKHKTAFDKLHADEMRKARDRSNPFELIRGGMFLNRAAMKMANMDKRFDFMFTKPVHQNGEPMVGKDELLYFADVCAGPGGFTEYVLWRKKWRAKGFGLTLKASNDFKLDDFYAGPAESFEPHYGAADDGNIYTPANIESFRDLIFEQTDNKGVHFMMADGGFSVAGEENLQEILSKQLYLCQCLVALFVVRTNGHFVTKLFDLFTPFSVGIIYLMYRCFEKICIFKPNTSRPANSERYLVCKWKRSESVIEDIRKYMENVNKLLCNVYGKNEKAKEEAKESKEKVVELDVYEIVLMDIMKSDENFFNYMIKSNNELASRQIVNLKKVVAFVKNPNLLEARQKDLKEQCLKYWEVPDDLRHAPKCPMPSNRLFSLAFGKDSKMPAPTELSKDGDLRSDILKKEFLSIYDWQCVTLQDHEKTTLFYGQGRKRVHKWGSSSWSELPSEHSLLELSPGTLVYGELVYEFIGEGKGLRKSAAFHIIDAYQLGKEVVGNLKYDERYEICQLFCKAMTRRGCPVRMKKLHKLFEVPSLLNEGLVRKQLKNVSIHRLCFPIPPFHHEVTSLLFLSSTANGWCKHWSKSQSKFYYYHGKSKASKYEDHVNMEVFNTFGLTMERLKIWSWKNYVPDCHPPRSVTDKLINFLRTNTVHKRT", "md5" : "b5002be631df5395eb5ca97eced38bc7", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 260, "end" : 284, "location-fragments" : [ { "start" : 260, "end" : 284, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 722, "end" : 742, "location-fragments" : [ { "start" : 722, "end" : 742, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PS50174", "name" : "G_PATCH", "description" : "G-patch domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000467", "name" : "G_patch_dom", "description" : "G-patch domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 313, "end" : 359, "score" : 14.288, "alignment" : "TSGAVSKMMEKMGYSSGKGLGKHAQGVVEPVALSSQRGRRGLGHIVE", "location-fragments" : [ { "start" : 313, "end" : 359, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50174" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 107, "end" : 129, "location-fragments" : [ { "start" : 107, "end" : 129, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.40.50.12760", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 366, "end" : 814, "hmmStart" : 38, "hmmEnd" : 409, "hmmLength" : 410, "hmmBounds" : "COMPLETE", "evalue" : 4.1E-166, "score" : 555.0, "envelopeStart" : 366, "envelopeEnd" : 814, "postProcessed" : true, "location-fragments" : [ { "start" : 366, "end" : 814, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-166, "score" : 555.8, "model-ac" : "4n49A00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 236, "end" : 252, "location-fragments" : [ { "start" : 236, "end" : 252, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR16121:SF0", "name" : "CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR030376", "name" : "Cap_mRNA_MeTrfase_1", "description" : "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1", "type" : "FAMILY", "goXRefs" : [ { "name" : "7-methylguanosine mRNA capping", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006370" }, { "name" : "mRNA methylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0080009" }, { "name" : "mRNA (nucleoside-2'-O-)-methyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004483" } ], "pathwayXRefs" : [ { "name" : "Mrna capping II", "databaseName" : "MetaCyc", "id" : "PWY-7379" } ] } }, "locations" : [ { "start" : 275, "end" : 1075, "hmmStart" : 19, "hmmEnd" : 781, "hmmLength" : 809, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 256, "envelopeEnd" : 1096, "location-fragments" : [ { "start" : 275, "end" : 1075, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-240, "familyName" : "CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1", "score" : 801.8, "model-ac" : "PTHR16121:SF0" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 285, "end" : 301, "location-fragments" : [ { "start" : 285, "end" : 301, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF01728", "name" : "FtsJ", "description" : "FtsJ-like methyltransferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002877", "name" : "rRNA_MeTrfase_FtsJ_dom", "description" : "Ribosomal RNA methyltransferase FtsJ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "methylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0032259" }, { "name" : "methyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008168" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 484, "end" : 694, "hmmStart" : 2, "hmmEnd" : 176, "hmmLength" : 177, "hmmBounds" : "INCOMPLETE", "evalue" : 9.1E-36, "score" : 123.6, "envelopeStart" : 483, "envelopeEnd" : 695, "postProcessed" : true, "location-fragments" : [ { "start" : 484, "end" : 694, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-36, "score" : 124.5, "model-ac" : "PF01728" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 89, "end" : 106, "location-fragments" : [ { "start" : 89, "end" : 106, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 145, "end" : 161, "location-fragments" : [ { "start" : 145, "end" : 161, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR16121", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 275, "end" : 1075, "hmmStart" : 19, "hmmEnd" : 781, "hmmLength" : 809, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 256, "envelopeEnd" : 1096, "location-fragments" : [ { "start" : 275, "end" : 1075, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-240, "familyName" : "CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1", "score" : 801.8, "model-ac" : "PTHR16121" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 200, "end" : 220, "location-fragments" : [ { "start" : 200, "end" : 220, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 314, "location-fragments" : [ { "start" : 1, "end" : 314, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 130, "end" : 144, "location-fragments" : [ { "start" : 130, "end" : 144, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF01585", "name" : "G-patch", "description" : "G-patch domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000467", "name" : "G_patch_dom", "description" : "G-patch domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 313, "end" : 356, "hmmStart" : 1, "hmmEnd" : 44, "hmmLength" : 45, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.5E-13, "score" : 48.6, "envelopeStart" : 313, "envelopeEnd" : 356, "postProcessed" : true, "location-fragments" : [ { "start" : 313, "end" : 356, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-13, "score" : 49.6, "model-ac" : "PF01585" }, { "signature" : { "accession" : "PS51613", "name" : "SAM_MT_RRMJ", "description" : "RrmJ-type ribose 2'-O-methyltransferase (EC 2.1.1.57) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR025816", "name" : "RrmJ-type_MeTrfase", "description" : "RrmJ-type ribose 2-O-methyltransferase domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Mrna capping II", "databaseName" : "MetaCyc", "id" : "PWY-7379" } ] } }, "locations" : [ { "start" : 482, "end" : 696, "score" : 63.573, "alignment" : "MFLNRAAMKMANMDKRFDFmftKPvhqngepmvGKDELLYFADVCAGPGGFTEYVLWRKKWRAKGFGLTLKASNDFKLDDFYAGPAESFEPHYGAADDGNIYTPANIESFRDLIFEQTDNKGVHFMMADGGFSVAGEENLQEILSKQLYLCQCLVALFVVRTNGHFVTKLFDLFTPFSVGIIYLMYRCFEKICIFKPNTSRPANSERYLVCKWKR", "location-fragments" : [ { "start" : 482, "end" : 696, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51613" }, { "signature" : { "accession" : "SSF53335", "name" : "S-adenosyl-L-methionine-dependent methyltransferases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029063", "name" : "SAM-dependent_MTases", "description" : "S-adenosyl-L-methionine-dependent methyltransferase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 484, "end" : 695, "hmmLength" : 180, "location-fragments" : [ { "start" : 484, "end" : 695, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.49E-15, "model-ac" : "0046568" }, { "signature" : { "accession" : "SM00443", "name" : "G-patch_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000467", "name" : "G_patch_dom", "description" : "G-patch domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 311, "end" : 357, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 3.6E-14, "score" : 63.1, "location-fragments" : [ { "start" : 311, "end" : 357, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-14, "score" : 63.1, "model-ac" : "SM00443" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 47, "end" : 88, "location-fragments" : [ { "start" : 47, "end" : 88, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910184.1 PREDICTED: cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 [Bemisia tabaci]", "id" : "XP_018910184.1" } ] },{ "sequence" : "MAELLLDPNIRCWVFLPIVVITFLVGIVRHYVSLLITTQKKAEITQIQDSQVMLRARALREHGKYLPKQSFLMRRHFFNNEETGYFKTQTRAAPAQNPMTDPSMLVDMLKGNVTNVLPMIIIGGWINWMFSGFVTTKVPFPLTLRFKPMLQRGVELVSLDAAWVSSASWYFLNVFGLRSIYALVLGENNAADQSKITQDQMSGAAMAMPLDPKAAFKAEWEALEICEHSWTLSNIEAELLESADFKFETAEEQNHM", "md5" : "852c46e283feaebfbb6925802bcd3763", "matches" : [ { "signature" : { "accession" : "PF01956", "name" : "EMC3_TMCO1", "description" : "Integral membrane protein EMC3/TMCO1-like", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002809", "name" : "EMC3/TMCO1", "description" : "Integral membrane protein EMC3/TMCO1-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3, "end" : 189, "hmmStart" : 1, "hmmEnd" : 170, "hmmLength" : 170, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-53, "score" : 181.2, "envelopeStart" : 3, "envelopeEnd" : 189, "postProcessed" : true, "location-fragments" : [ { "start" : 3, "end" : 189, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-53, "score" : 181.2, "model-ac" : "PF01956" }, { "signature" : { "accession" : "PTHR13116", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR008568", "name" : "EMC3", "description" : "ER membrane protein complex subunit 3", "type" : "FAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 246, "hmmStart" : 4, "hmmEnd" : 248, "hmmLength" : 261, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 255, "location-fragments" : [ { "start" : 2, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-124, "familyName" : "ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3", "score" : 415.9, "model-ac" : "PTHR13116" }, { "signature" : { "accession" : "SM01415", "name" : "DUF106_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002809", "name" : "EMC3/TMCO1", "description" : "Integral membrane protein EMC3/TMCO1-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3, "end" : 189, "hmmStart" : 1, "hmmEnd" : 248, "hmmLength" : 248, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-92, "score" : 323.9, "location-fragments" : [ { "start" : 3, "end" : 189, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-92, "score" : 323.9, "model-ac" : "SM01415" }, { "signature" : { "accession" : "PTHR13116:SF7", "name" : "ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 246, "hmmStart" : 4, "hmmEnd" : 248, "hmmLength" : 261, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 255, "location-fragments" : [ { "start" : 2, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-124, "familyName" : "ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3", "score" : 415.9, "model-ac" : "PTHR13116:SF7" }, { "signature" : { "accession" : "PIRSF010045", "name" : "TMP_111", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR008568", "name" : "EMC3", "description" : "ER membrane protein complex subunit 3", "type" : "FAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 244, "hmmStart" : 2, "hmmEnd" : 242, "hmmLength" : 263, "hmmBounds" : "INCOMPLETE", "evalue" : 3.5E-90, "score" : 297.9, "envelopeStart" : 1, "envelopeEnd" : 244, "postProcessed" : false, "location-fragments" : [ { "start" : 1, "end" : 244, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-90, "score" : 298.1, "model-ac" : "PIRSF010045" } ], "xref" : [ { "name" : "XP_018910515.1 PREDICTED: ER membrane protein complex subunit 3 [Bemisia tabaci]", "id" : "XP_018910515.1" } ] },{ "sequence" : "MLKPTKLREGISLNSGHNGLLSIDAGRLNALIKNELITNVYDVEQTPFARGKFAAVRKCTHKVTGIEYAAKFIRKRRRSMDTRQDILHEVAVLCLAEMSSRIVALHEVYETPTDMALVLELVPGGELQRVVDLQDGLEEREVIRVMRQILEGLIYLHDLNIAHLDLKPQNLLLTANYPDCDIKLCDFGISRVIQSGVEVREILGTPDYVAPEILNYEPISLGTDVWSLGILAYVLLSGHSPFAGDTKQETFCNISQCNLDFPDDLFGSVSQTAKDFINATLVPEPGARLTARQCLSHPWLSSCSSPLNLVTPLSITSQPDGDKEEASSRLPTVPASTVSISSVNYQLSSCISKCGAQCGCNHEKEKHSSITSSPVVEIILDSRSIIC", "md5" : "bff1454efd97883a71f08588b766aea9", "matches" : [ { "signature" : { "accession" : "PS50011", "name" : "PROTEIN_KINASE_DOM", "description" : "Protein kinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 300, "score" : 42.153, "alignment" : "DVEQTPFARGKFAAVRKCTHKVTGIEYAAKFIRKRRRSMDTRQDILHEVAVLC-LaeMSSRIVALHEVYETPTDMALVLELVPGGELQRVVDLQ--DgLEEREVIRVMRQILEGLIYLHDLNIAHLDLKPQNLLLTANypdCDIKLCDFGISRVIQ---SgvEVREILGTPDYVAPEIL-NYEPISLGTDVWSLGILAYVLLSGHSPFAG-DTKQETFCNISQC---------NLdfpddlfgsVSQTAKDFINATLVPEPGARLTARQCLSHPWL", "location-fragments" : [ { "start" : 42, "end" : 300, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50011" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 351, "hmmLength" : 364, "location-fragments" : [ { "start" : 50, "end" : 351, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.47E-75, "model-ac" : "0041927" }, { "signature" : { "accession" : "PTHR24342:SF12", "name" : "DEATH-ASSOCIATED PROTEIN KINASE RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 331, "hmmStart" : 5, "hmmEnd" : 292, "hmmLength" : 595, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 11, "envelopeEnd" : 382, "location-fragments" : [ { "start" : 14, "end" : 331, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-157, "familyName" : "DEATH-ASSOCIATED PROTEIN KINASE RELATED", "score" : 528.6, "model-ac" : "PTHR24342:SF12" }, { "signature" : { "accession" : "PF00069", "name" : "Pkinase", "description" : "Protein kinase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 300, "hmmStart" : 9, "hmmEnd" : 264, "hmmLength" : 264, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.4E-64, "score" : 216.1, "envelopeStart" : 44, "envelopeEnd" : 300, "postProcessed" : true, "location-fragments" : [ { "start" : 50, "end" : 300, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-64, "score" : 216.5, "model-ac" : "PF00069" }, { "signature" : { "accession" : "G3DSA:3.30.200.20", "name" : "Phosphorylase Kinase; domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 45, "end" : 127, "hmmStart" : 7, "hmmEnd" : 86, "hmmLength" : 89, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.6E-25, "score" : 90.1, "envelopeStart" : 45, "envelopeEnd" : 130, "postProcessed" : true, "location-fragments" : [ { "start" : 45, "end" : 127, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-25, "score" : 91.2, "model-ac" : "3lm5A01" }, { "signature" : { "accession" : "PS00108", "name" : "PROTEIN_KINASE_ST", "description" : "Serine/Threonine protein kinases active-site signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR008271", "name" : "Ser/Thr_kinase_AS", "description" : "Serine/threonine-protein kinase, active site", "type" : "ACTIVE_SITE", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 161, "end" : 173, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I3M2I4M", "alignment" : "IaHlDLKpqNLLL", "location-fragments" : [ { "start" : 161, "end" : 173, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00108" }, { "signature" : { "accession" : "G3DSA:1.10.510.10", "name" : "Transferase(Phosphotransferase) domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 128, "end" : 343, "hmmStart" : 2, "hmmEnd" : 184, "hmmLength" : 256, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.8E-58, "score" : 198.4, "envelopeStart" : 124, "envelopeEnd" : 343, "postProcessed" : true, "location-fragments" : [ { "start" : 128, "end" : 343, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.7E-58, "score" : 198.7, "model-ac" : "1kobA02" }, { "signature" : { "accession" : "PTHR24342", "name" : "SERINE/THREONINE-PROTEIN KINASE 17", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 331, "hmmStart" : 5, "hmmEnd" : 292, "hmmLength" : 595, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 11, "envelopeEnd" : 382, "location-fragments" : [ { "start" : 14, "end" : 331, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-157, "familyName" : "DEATH-ASSOCIATED PROTEIN KINASE RELATED", "score" : 528.6, "model-ac" : "PTHR24342" }, { "signature" : { "accession" : "SM00220", "name" : "serkin_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 300, "hmmStart" : 1, "hmmEnd" : 231, "hmmLength" : 231, "hmmBounds" : "COMPLETE", "evalue" : 9.1E-78, "score" : 274.3, "location-fragments" : [ { "start" : 42, "end" : 300, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.1E-78, "score" : 274.3, "model-ac" : "SM00220" } ], "xref" : [ { "name" : "XP_018910079.1 PREDICTED: death-associated protein kinase related-like [Bemisia tabaci]", "id" : "XP_018910079.1" }, { "name" : "XP_018910078.1 PREDICTED: death-associated protein kinase related-like [Bemisia tabaci]", "id" : "XP_018910078.1" } ] },{ "sequence" : "MKFKNRTFLNSPLILTMRLFGVFPINPDTLECSRFDVIYCGCSGVLSILELLYTPVFIIHQKDKLVPANFPATTTIMFIQSTITSIAARYTALHRVIKYFPRINDNIIKTTSLLYTHSLADEKYKRERALLRNRLLCIFIFIGVVGLNVNRVQCFIRMSEIIGDTIYFVYFIMFQNSAVLLIEIMFLRTVAQLNLNFSKINKELELILEETELFEKQAQRLMCKVEGAEKVNKDDKSSSRMTSTTHGHPIRSPYVWPSSGKSCDSTLKLNIEMVEIPEIFPMNTLSRLKRLFFLHIQCSEAVESSNSLFEVQLLFSVFRLFCVSFLVVYQHLSRYVEYGFAYTVLIYVYIFFIILRSTLLTSSTGCTISEAQYTKVLITKINNRFLDVDTKEELELFWEHITSSKLEFTACGFFTLNTRLIASAFVAGTTYLVILLQFNPEKQNMVS", "md5" : "540b4c4b84649c40cadf8643cbe3dcda", "matches" : [ { "signature" : { "accession" : "PTHR21143", "name" : "INVERTEBRATE GUSTATORY RECEPTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR013604", "name" : "7TM_chemorcpt", "description" : "7TM chemoreceptor", "type" : "FAMILY", "goXRefs" : [ { "name" : "sensory perception of taste", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0050909" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 11, "end" : 440, "hmmStart" : 11, "hmmEnd" : 389, "hmmLength" : 392, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 443, "location-fragments" : [ { "start" : 11, "end" : 440, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-26, "familyName" : "INVERTEBRATE GUSTATORY RECEPTOR", "score" : 94.6, "model-ac" : "PTHR21143" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 190, "end" : 210, "location-fragments" : [ { "start" : 190, "end" : 210, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF08395", "name" : "7tm_7", "description" : "7tm Chemosensory receptor", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013604", "name" : "7TM_chemorcpt", "description" : "7TM chemoreceptor", "type" : "FAMILY", "goXRefs" : [ { "name" : "sensory perception of taste", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0050909" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 12, "end" : 439, "hmmStart" : 3, "hmmEnd" : 368, "hmmLength" : 371, "hmmBounds" : "INCOMPLETE", "evalue" : 2.9E-22, "score" : 79.4, "envelopeStart" : 11, "envelopeEnd" : 442, "postProcessed" : true, "location-fragments" : [ { "start" : 12, "end" : 439, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.1E-23, "score" : 81.4, "model-ac" : "PF08395" } ], "xref" : [ { "name" : "XP_018910041.1 PREDICTED: gustatory receptor for sugar taste 43a-like [Bemisia tabaci]", "id" : "XP_018910041.1" } ] },{ "sequence" : "MTTNNYFGFTHGTQYSATPGTTYPTQQTGYSVTPGATAAAYPTQRTATGYETYQTQATPTAYAVPAGATTATTYDYGYARTAHSSPTAYDAKAYYQQQANPATPVTPAYSTSDYQTAGAAIVKPQYSATYSTQTTPQRQVVPPKPAVSAVQYSQYAPPQQQQQTPAQAVSSYTASYSTPASIQPTSQLNKAIGSAPRAITQRAPQQAVQQQTTGYQYTQRHPFKPQQQQQQQPPPQQVSQVQQLSQLQQQQQQQQHQQIKKPYQASPVSNVGSYQVNNPSTAQAAFVAQSTAAATNSNYNKPKPGYDTALFNAASHYINQQSGPNQNKPFYKKSFGNNASGLKNLRPKAPPKSQQLHYCEVCKISCAGPLTYREHLEGQKHKKKEAALKSDAPAPTISRGPISLHCDLCAVTCTGQDAYGAHIRGNKHQKVLKLHAMLGKPVPDIPEDPKIVVAKSIAAAKANQNTTAPDGKKTVVVPPKVNFVQSGSLSTTTKPEPKAEGKENTKSESTPEPKTEDIEMAAATLLENEVTPVGHEFVEEIKDELGKLVSFNCKLCECKFNDPNAKEMHMKGRRHRLAFKKKVNPNLQVDVKPSFNKKKHFEEKTRRTGGGGGPREEFMRGNQRNMHWQDRMMEVEERMYWDERRRFEEEMEFMEWGRRFHGPGMMPPPFPPGPGPRMMGPPFMPPPPPPQFPRRLDTSDDRHVIARHAAVYPNEQELKALQKIVSHTEKALKLVSDFLTENAQSTTDKKNGTSEVKTEVKVEPKTAESPAKPNATPNKKGPQKTKEDGRDGSLFSFEKETEERVLKGVMRVESLAKGLLLHGDTHVKLVVLCSEKPTRALLVKVAANLPSQLSIVAPEDSYLTNMKSEEAAITVQTKTEPKLTVSVILTSPLLREQVNAAGSDAPAAQSTPDPPDLLNKKKCLDALAALRHAKWFQARVAGMQNCLMIIRIFRDLCQRVPTWAPFSPWAMELLCEKALSSAGMPLSPGDSLRRVLEAVSSGVILQNGPGILDPCEKEPVDAAANLTPQQREDITASAQHALRLLAFRQIHKVLGMEPLPAPPPMPTNKFNNRGGYNRFGRKRRRDNSSGENTDSDAGVNEKKDKKDTDVVIKVEGAKVSSPAAATTPAKPAEAAKAPAATPAAAKGSLKSPAAAKPAVKK", "md5" : "93bbdf28fef737e67e6c1bfd5c80f6af", "matches" : [ { "signature" : { "accession" : "PTHR45762", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 151, "end" : 1108, "hmmStart" : 1, "hmmEnd" : 793, "hmmLength" : 807, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 151, "envelopeEnd" : 1118, "location-fragments" : [ { "start" : 151, "end" : 1108, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.6E-263, "familyName" : "ZINC-FINGER PROTEIN AT 72D, ISOFORM B", "score" : 877.5, "model-ac" : "PTHR45762" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 151, "end" : 170, "location-fragments" : [ { "start" : 151, "end" : 170, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR45762:SF5", "name" : "ZINC-FINGER PROTEIN AT 72D, ISOFORM B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 151, "end" : 1108, "hmmStart" : 1, "hmmEnd" : 793, "hmmLength" : 807, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 151, "envelopeEnd" : 1118, "location-fragments" : [ { "start" : 151, "end" : 1108, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.6E-263, "familyName" : "ZINC-FINGER PROTEIN AT 72D, ISOFORM B", "score" : 877.5, "model-ac" : "PTHR45762:SF5" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 531, "end" : 582, "hmmLength" : 72, "location-fragments" : [ { "start" : 531, "end" : 582, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.01E-8, "model-ac" : "0053677" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 746, "end" : 795, "location-fragments" : [ { "start" : 746, "end" : 795, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 185, "end" : 276, "location-fragments" : [ { "start" : 185, "end" : 276, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 781, "end" : 795, "location-fragments" : [ { "start" : 781, "end" : 795, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1081, "end" : 1113, "location-fragments" : [ { "start" : 1081, "end" : 1113, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 348, "end" : 391, "hmmStart" : 15, "hmmEnd" : 50, "hmmLength" : 60, "hmmBounds" : "COMPLETE", "evalue" : 2.0E-11, "score" : 45.2, "envelopeStart" : 348, "envelopeEnd" : 391, "postProcessed" : true, "location-fragments" : [ { "start" : 348, "end" : 391, "dc-status" : "CONTINUOUS" } ] }, { "start" : 542, "end" : 584, "hmmStart" : 18, "hmmEnd" : 48, "hmmLength" : 60, "hmmBounds" : "COMPLETE", "evalue" : 3.1E-6, "score" : 28.6, "envelopeStart" : 542, "envelopeEnd" : 584, "postProcessed" : true, "location-fragments" : [ { "start" : 542, "end" : 584, "dc-status" : "CONTINUOUS" } ] }, { "start" : 401, "end" : 441, "hmmStart" : 18, "hmmEnd" : 56, "hmmLength" : 60, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-8, "score" : 35.7, "envelopeStart" : 401, "envelopeEnd" : 441, "postProcessed" : true, "location-fragments" : [ { "start" : 401, "end" : 441, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-28, "score" : 100.6, "model-ac" : "2mknA00" }, { "signature" : { "accession" : "SM00355", "name" : "c2h2final6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 357, "end" : 381, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 5.7, "score" : 15.5, "location-fragments" : [ { "start" : 357, "end" : 381, "dc-status" : "CONTINUOUS" } ] }, { "start" : 404, "end" : 428, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 7.0, "score" : 14.7, "location-fragments" : [ { "start" : 404, "end" : 428, "dc-status" : "CONTINUOUS" } ] }, { "start" : 551, "end" : 575, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.66, "score" : 19.0, "location-fragments" : [ { "start" : 551, "end" : 575, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-10, "score" : 49.2, "model-ac" : "SM00355" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 553, "end" : 575, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M5I1M", "alignment" : "CklCeckFndpnakemHmkgrrH", "location-fragments" : [ { "start" : 553, "end" : 575, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS51703", "name" : "DZF", "description" : "DZF domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR006561", "name" : "DZF_dom", "description" : "DZF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 681, "end" : 1089, "score" : 95.983, "alignment" : "PPFM-PPPPPPQFPRRLDTSDDRHVIARHAAVYPNEQELKALQKIVSHTEKALKLVSDFLTENAQSTTDKKngtsevktevkvepktaespakpnatpnkkgpqktkedgrdGSLFSFEKETEERVLKGVMRVESLAKGLLLHGDTHVKLVVLCSEKPTRALLVKVAANLPSQLSIvapEDSYLTNMKSEEAAITVQTKtepkltvsviltspllREQVNAAGSDAPAAQSTPDPPDLLNKKKCLDALAALRHAKWFQARVAGMQNCLMIIRIFRDLCQRVPTWAPFSPWAMELLCEKALSSAGMPLSPGDSLRRVLEAVSSGVILQNGPGILDPCEKEPVDAAANLTPQQREDITASAQHALRLLAFRQIHKVLGMEPLPAPPPMPTNKFNN------RGGYNRFGRKRRRDNSS", "location-fragments" : [ { "start" : 681, "end" : 1089, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51703" }, { "signature" : { "accession" : "SM00572", "name" : "rich3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006561", "name" : "DZF_dom", "description" : "DZF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 805, "end" : 1062, "hmmStart" : 1, "hmmEnd" : 263, "hmmLength" : 263, "hmmBounds" : "COMPLETE", "evalue" : 7.9E-126, "score" : 434.0, "location-fragments" : [ { "start" : 805, "end" : 1062, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-126, "score" : 434.0, "model-ac" : "SM00572" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 752, "end" : 766, "location-fragments" : [ { "start" : 752, "end" : 766, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 404, "end" : 437, "hmmLength" : 72, "location-fragments" : [ { "start" : 404, "end" : 437, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.38E-7, "model-ac" : "0053677" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 152, "end" : 170, "location-fragments" : [ { "start" : 152, "end" : 170, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 344, "end" : 389, "hmmLength" : 72, "location-fragments" : [ { "start" : 344, "end" : 389, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.12E-10, "model-ac" : "0053677" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1057, "end" : 1161, "location-fragments" : [ { "start" : 1057, "end" : 1161, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 496, "end" : 515, "location-fragments" : [ { "start" : 496, "end" : 515, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 486, "end" : 516, "location-fragments" : [ { "start" : 486, "end" : 516, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF12874", "name" : "zf-met", "description" : "Zinc-finger of C2H2 type", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 358, "end" : 381, "hmmStart" : 2, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.5E-6, "score" : 27.2, "envelopeStart" : 357, "envelopeEnd" : 381, "postProcessed" : true, "location-fragments" : [ { "start" : 358, "end" : 381, "dc-status" : "CONTINUOUS" } ] }, { "start" : 551, "end" : 575, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-5, "score" : 25.1, "envelopeStart" : 551, "envelopeEnd" : 575, "postProcessed" : true, "location-fragments" : [ { "start" : 551, "end" : 575, "dc-status" : "CONTINUOUS" } ] }, { "start" : 405, "end" : 428, "hmmStart" : 2, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.5E-4, "score" : 22.0, "envelopeStart" : 404, "envelopeEnd" : 428, "postProcessed" : true, "location-fragments" : [ { "start" : 405, "end" : 428, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-18, "score" : 66.2, "model-ac" : "PF12874" }, { "signature" : { "accession" : "PF07528", "name" : "DZF", "description" : "DZF domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006561", "name" : "DZF_dom", "description" : "DZF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 811, "end" : 1061, "hmmStart" : 1, "hmmEnd" : 247, "hmmLength" : 248, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.0E-66, "score" : 222.9, "envelopeStart" : 811, "envelopeEnd" : 1062, "postProcessed" : true, "location-fragments" : [ { "start" : 811, "end" : 1061, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-66, "score" : 223.4, "model-ac" : "PF07528" }, { "signature" : { "accession" : "SM00451", "name" : "ZnF_U1_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003604", "name" : "Matrin/U1-like-C_Znf_C2H2", "description" : "Matrin/U1-C-like, C2H2-type zinc finger", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 548, "end" : 582, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 37, "hmmBounds" : "COMPLETE", "evalue" : 0.0012, "score" : 28.1, "location-fragments" : [ { "start" : 548, "end" : 582, "dc-status" : "CONTINUOUS" } ] }, { "start" : 354, "end" : 388, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 37, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-7, "score" : 39.6, "location-fragments" : [ { "start" : 354, "end" : 388, "dc-status" : "CONTINUOUS" } ] }, { "start" : 401, "end" : 435, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 37, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-4, "score" : 30.7, "location-fragments" : [ { "start" : 401, "end" : 435, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.5E-25, "score" : 98.4, "model-ac" : "SM00451" } ], "xref" : [ { "name" : "XP_018909583.1 PREDICTED: zinc finger RNA-binding protein-like isoform X4 [Bemisia tabaci]", "id" : "XP_018909583.1" } ] },{ "sequence" : "MFKGLHHSTDPGDVISDLKSKGFKPISVINIVQKKRIVTKTSKEKSVKNSPQNIPVNSQKSDKMPENIPDNSNTNNNPDANSPAISNSESNNMSQTLPQDEQPQPDPNTNRDQNPVNQDHNTQTEGI", "md5" : "3452f7586098becf611eec3201d0528c", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 44, "end" : 127, "location-fragments" : [ { "start" : 44, "end" : 127, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 127, "location-fragments" : [ { "start" : 1, "end" : 127, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910024.1 PREDICTED: putative uncharacterized protein DDB_G0283223 [Bemisia tabaci]", "id" : "XP_018910024.1" } ] },{ "sequence" : "MPKLKIQLEEHSALSTPEDYNPVIPPNDKSAKDPVGDVSRIDCTSPSMQAPPEACTSWESSVMPGNPSPPSGGSHPQDSNNTRLASVEETEDTSPSSILDSPSAHPPKIECEDEKDYASWTNQLHTSIEIKSEPTPQTDESELRLGRGGGEHDLENDIRDFVPTTARVKREDMSSPLPDHSHESWIDLSDTNIEIKSEPPTQTNASESEFVEHIRTHASENPFTCGECLSLFSSESALITHMQTHDGEIPFNYSHCSSSSSIEDNLKKHMRTHTRNEKLLSCNPCSSSFSSKDDLKMHMRTHTGEKPFSCSHCTACFSHKKSLTAHVRKHTGEKPFSCSHCTACFSHKKSLTAHVRTHTGEKPFSCNHCSSSFSRKHNLKRHMRTHTGEKPFSCSHCSSSFSIKNYLKMHMRTHTGEKPFSCSHCTACFSHKKSLTEHVRTHTGEKPFSCSHCTACFSHKKSLTEHVRTHTGEKPFSCNHCSSSFSSKDYLKVHMRTHTGEKPFSCSHCSSSFLRKIHLKMHMRTHTGEKPFSCSHCTACFSHKKSLTEHVRTHTGEKPFSCNHCSSSFSIKINLKMHMRTHTGEKPFSCSLTEHVRTHTGEKPFSCNHCSSSFSRKHNLKMHMRTHTGEKPFSCSHCSSSFSIKKNLKTHMRTHTGEKVRTHTGEKPFSCSHCRACFSHKKSLTEHVRTHTGEKPFSCNHCSSSFSSKKSLKKHMQTHTSEKPFSCSHCTACFSHKKSLTEHVRAHTGEKPFRCNHCSSSFSSKDFIKVHMRTHTGEKPFSCSHCTACFSHKNSLTEHVRTHTGEKPFSCNHCSSSFSIKNSLKKHMRTHTGEKPFSCSHCMACFAQKHTLTEHVRTHTGAKPFSCSHCTSCFSHKKSLTAHVRTHTGEKPFSCSHCTACFSHKKSLTEHV", "md5" : "b2ca9895127a03bbdcaee095bc044e65", "matches" : [ { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 422, "end" : 442, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCtacFshkkslteHvrtH", "location-fragments" : [ { "start" : 422, "end" : 442, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 237, "end" : 274, "hmmStart" : 1, "hmmEnd" : 43, "hmmLength" : 44, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.2E-10, "score" : 41.9, "envelopeStart" : 232, "envelopeEnd" : 274, "postProcessed" : true, "location-fragments" : [ { "start" : 237, "end" : 274, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-293, "score" : 947.1, "model-ac" : "2i13A01" }, { "signature" : { "accession" : "PTHR24376:SF131", "name" : "ZINC FINGER PROTEIN 467", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 592, "end" : 911, "hmmStart" : 351, "hmmEnd" : 662, "hmmLength" : 679, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 591, "envelopeEnd" : 912, "location-fragments" : [ { "start" : 592, "end" : 911, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "ZINC FINGER PROTEIN 467", "score" : 1197.9, "model-ac" : "PTHR24376:SF131" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 888, "end" : 912, "hmmStart" : 3, "hmmEnd" : 29, "hmmLength" : 36, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.4E-7, "score" : 33.2, "envelopeStart" : 884, "envelopeEnd" : 912, "postProcessed" : true, "location-fragments" : [ { "start" : 888, "end" : 912, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-219, "score" : 711.8, "model-ac" : "2drpA01" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 605, "end" : 632, "score" : 16.623, "alignment" : "FSCNHCSSSFSRKHNLKMHMRTHTGEKP", "location-fragments" : [ { "start" : 605, "end" : 632, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 867, "end" : 887, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCtscFshkksltaHvrtH", "location-fragments" : [ { "start" : 867, "end" : 887, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 317, "end" : 373, "hmmLength" : 61, "location-fragments" : [ { "start" : 317, "end" : 373, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.08E-17, "model-ac" : "0050784" }, { "signature" : { "accession" : "PTHR24376", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 592, "end" : 911, "hmmStart" : 351, "hmmEnd" : 662, "hmmLength" : 679, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 591, "envelopeEnd" : 912, "location-fragments" : [ { "start" : 592, "end" : 911, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "ZINC FINGER PROTEIN 467", "score" : 1197.9, "model-ac" : "PTHR24376" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 628, "end" : 658, "hmmStart" : 4, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.9E-14, "score" : 55.3, "envelopeStart" : 623, "envelopeEnd" : 658, "postProcessed" : true, "location-fragments" : [ { "start" : 628, "end" : 658, "dc-status" : "CONTINUOUS" } ] }, { "start" : 527, "end" : 554, "hmmStart" : 4, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "INCOMPLETE", "evalue" : 9.8E-13, "score" : 49.9, "envelopeStart" : 522, "envelopeEnd" : 557, "postProcessed" : true, "location-fragments" : [ { "start" : 527, "end" : 554, "dc-status" : "CONTINUOUS" } ] }, { "start" : 776, "end" : 804, "hmmStart" : 4, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "INCOMPLETE", "evalue" : 4.3E-13, "score" : 51.0, "envelopeStart" : 771, "envelopeEnd" : 806, "postProcessed" : true, "location-fragments" : [ { "start" : 776, "end" : 804, "dc-status" : "CONTINUOUS" } ] }, { "start" : 415, "end" : 443, "hmmStart" : 4, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "INCOMPLETE", "evalue" : 9.3E-13, "score" : 49.9, "envelopeStart" : 410, "envelopeEnd" : 445, "postProcessed" : true, "location-fragments" : [ { "start" : 415, "end" : 443, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-245, "score" : 794.6, "model-ac" : "2m9aA01" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 865, "end" : 892, "score" : 15.376, "alignment" : "FSCSHCTSCFSHKKSLTAHVRTHTGEKP", "location-fragments" : [ { "start" : 865, "end" : 892, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 592, "end" : 639, "hmmLength" : 61, "location-fragments" : [ { "start" : 592, "end" : 639, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.08E-18, "model-ac" : "0050784" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 394, "end" : 414, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCsssFsiknylkmHmrtH", "location-fragments" : [ { "start" : 394, "end" : 414, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 809, "end" : 836, "score" : 16.415, "alignment" : "FSCNHCSSSFSIKNSLKKHMRTHTGEKP", "location-fragments" : [ { "start" : 809, "end" : 836, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PF13894", "name" : "zf-C2H2_4", "description" : "C2H2-type zinc finger", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 697, "end" : 719, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 24, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 8.1E-4, "score" : 20.0, "envelopeStart" : 697, "envelopeEnd" : 720, "postProcessed" : true, "location-fragments" : [ { "start" : 697, "end" : 719, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-48, "score" : 159.3, "model-ac" : "PF13894" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 444, "end" : 472, "hmmStart" : 6, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 9.1E-13, "score" : 49.7, "envelopeStart" : 441, "envelopeEnd" : 475, "postProcessed" : true, "location-fragments" : [ { "start" : 444, "end" : 472, "dc-status" : "CONTINUOUS" } ] }, { "start" : 361, "end" : 388, "hmmStart" : 7, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 1.3E-15, "score" : 58.9, "envelopeStart" : 358, "envelopeEnd" : 391, "postProcessed" : true, "location-fragments" : [ { "start" : 361, "end" : 388, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-245, "score" : 795.4, "model-ac" : "2enaA00" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 781, "end" : 808, "score" : 15.708, "alignment" : "FSCSHCTACFSHKNSLTEHVRTHTGEKP", "location-fragments" : [ { "start" : 781, "end" : 808, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PTHR24376:SF131", "name" : "ZINC FINGER PROTEIN 467", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 264, "end" : 591, "hmmStart" : 321, "hmmEnd" : 647, "hmmLength" : 679, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 259, "envelopeEnd" : 594, "location-fragments" : [ { "start" : 264, "end" : 591, "dc-status" : "CONTINUOUS" } ] }, { "start" : 206, "end" : 415, "hmmStart" : 459, "hmmEnd" : 667, "hmmLength" : 679, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 199, "envelopeEnd" : 415, "location-fragments" : [ { "start" : 206, "end" : 415, "dc-status" : "CONTINUOUS" } ] }, { "start" : 401, "end" : 659, "hmmStart" : 373, "hmmEnd" : 642, "hmmLength" : 679, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 401, "envelopeEnd" : 660, "location-fragments" : [ { "start" : 401, "end" : 659, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "ZINC FINGER PROTEIN 467", "score" : 1197.9, "model-ac" : "PTHR24376:SF131" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 208, "end" : 257, "hmmLength" : 61, "location-fragments" : [ { "start" : 208, "end" : 257, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.9E-12, "model-ac" : "0050784" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 448, "end" : 475, "score" : 15.48, "alignment" : "FSCSHCTACFSHKKSLTEHVRTHTGEKP", "location-fragments" : [ { "start" : 448, "end" : 475, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 671, "end" : 691, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCracFshkkslteHvrtH", "location-fragments" : [ { "start" : 671, "end" : 691, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 893, "end" : 912, "score" : 8.912, "alignment" : "FSCSHCTACFSHKKSLTEHV--------", "location-fragments" : [ { "start" : 893, "end" : 912, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 264, "end" : 317, "hmmLength" : 61, "location-fragments" : [ { "start" : 264, "end" : 317, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.11E-14, "model-ac" : "0050784" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 761, "end" : 818, "hmmLength" : 61, "location-fragments" : [ { "start" : 761, "end" : 818, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.27E-18, "model-ac" : "0050784" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 560, "end" : 587, "score" : 15.771, "alignment" : "FSCNHCSSSFSIKINLKMHMRTHTGEKP", "location-fragments" : [ { "start" : 560, "end" : 587, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 429, "end" : 485, "hmmLength" : 61, "location-fragments" : [ { "start" : 429, "end" : 485, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.07E-18, "model-ac" : "0050784" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 366, "end" : 386, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CnhCsssFsrkhnlkrHmrtH", "location-fragments" : [ { "start" : 366, "end" : 386, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 473, "end" : 500, "hmmStart" : 7, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 9.1E-16, "score" : 59.4, "envelopeStart" : 470, "envelopeEnd" : 503, "postProcessed" : true, "location-fragments" : [ { "start" : 473, "end" : 500, "dc-status" : "CONTINUOUS" } ] }, { "start" : 389, "end" : 414, "hmmStart" : 7, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 1.9E-14, "score" : 55.3, "envelopeStart" : 386, "envelopeEnd" : 419, "postProcessed" : true, "location-fragments" : [ { "start" : 389, "end" : 414, "dc-status" : "CONTINUOUS" } ] }, { "start" : 307, "end" : 331, "hmmStart" : 7, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 2.1E-11, "score" : 45.5, "envelopeStart" : 302, "envelopeEnd" : 335, "postProcessed" : true, "location-fragments" : [ { "start" : 307, "end" : 331, "dc-status" : "CONTINUOUS" } ] }, { "start" : 750, "end" : 775, "hmmStart" : 7, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 3.9E-14, "score" : 54.2, "envelopeStart" : 746, "envelopeEnd" : 780, "postProcessed" : true, "location-fragments" : [ { "start" : 750, "end" : 775, "dc-status" : "CONTINUOUS" } ] }, { "start" : 721, "end" : 749, "hmmStart" : 6, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 7.1E-11, "score" : 43.8, "envelopeStart" : 717, "envelopeEnd" : 752, "postProcessed" : true, "location-fragments" : [ { "start" : 721, "end" : 749, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-248, "score" : 804.0, "model-ac" : "2el4A00" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 607, "end" : 627, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CnhCsssFsrkhnlkmHmrtH", "location-fragments" : [ { "start" : 607, "end" : 627, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 504, "end" : 531, "score" : 15.854, "alignment" : "FSCSHCSSSFLRKIHLKMHMRTHTGEKP", "location-fragments" : [ { "start" : 504, "end" : 531, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 705, "end" : 762, "hmmLength" : 61, "location-fragments" : [ { "start" : 705, "end" : 762, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.28E-17, "model-ac" : "0050784" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 484, "end" : 541, "hmmLength" : 61, "location-fragments" : [ { "start" : 484, "end" : 541, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.93E-20, "model-ac" : "0050784" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 699, "end" : 719, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CnhCsssFsskkslkkHmqtH", "location-fragments" : [ { "start" : 699, "end" : 719, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 308, "end" : 335, "score" : 14.856, "alignment" : "FSCSHCTACFSHKKSLTAHVRKHTGEKP", "location-fragments" : [ { "start" : 308, "end" : 335, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 364, "end" : 391, "score" : 16.997, "alignment" : "FSCNHCSSSFSRKHNLKRHMRTHTGEKP", "location-fragments" : [ { "start" : 364, "end" : 391, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 450, "end" : 470, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCtacFshkkslteHvrtH", "location-fragments" : [ { "start" : 450, "end" : 470, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 859, "end" : 911, "hmmLength" : 53, "location-fragments" : [ { "start" : 859, "end" : 911, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.64E-13, "model-ac" : "0053891" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 201, "end" : 236, "hmmStart" : 16, "hmmEnd" : 51, "hmmLength" : 57, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.4E-5, "score" : 26.1, "envelopeStart" : 201, "envelopeEnd" : 241, "postProcessed" : true, "location-fragments" : [ { "start" : 201, "end" : 236, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-251, "score" : 813.1, "model-ac" : "4is1C00" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 336, "end" : 363, "score" : 15.355, "alignment" : "FSCSHCTACFSHKKSLTAHVRTHTGEKP", "location-fragments" : [ { "start" : 336, "end" : 363, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 839, "end" : 859, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCmacFaqkhtlteHvrtH", "location-fragments" : [ { "start" : 839, "end" : 859, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 420, "end" : 447, "score" : 15.48, "alignment" : "FSCSHCTACFSHKKSLTEHVRTHTGEKP", "location-fragments" : [ { "start" : 420, "end" : 447, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 534, "end" : 554, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCtacFshkkslteHvrtH", "location-fragments" : [ { "start" : 534, "end" : 554, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 630, "end" : 659, "hmmLength" : 32, "location-fragments" : [ { "start" : 630, "end" : 659, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.18E-8, "model-ac" : "0053892" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 310, "end" : 330, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCtacFshkksltaHvrkH", "location-fragments" : [ { "start" : 310, "end" : 330, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 223, "end" : 250, "score" : 12.778, "alignment" : "FTCGECLSLFSSESALITHMQTHDGEIP", "location-fragments" : [ { "start" : 223, "end" : 250, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 392, "end" : 419, "score" : 15.937, "alignment" : "FSCSHCSSSFSIKNYLKMHMRTHTGEKP", "location-fragments" : [ { "start" : 392, "end" : 419, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 532, "end" : 559, "score" : 15.48, "alignment" : "FSCSHCTACFSHKKSLTEHVRTHTGEKP", "location-fragments" : [ { "start" : 532, "end" : 559, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PTHR24376", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 264, "end" : 591, "hmmStart" : 321, "hmmEnd" : 647, "hmmLength" : 679, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 259, "envelopeEnd" : 594, "location-fragments" : [ { "start" : 264, "end" : 591, "dc-status" : "CONTINUOUS" } ] }, { "start" : 206, "end" : 415, "hmmStart" : 459, "hmmEnd" : 667, "hmmLength" : 679, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 199, "envelopeEnd" : 415, "location-fragments" : [ { "start" : 206, "end" : 415, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "ZINC FINGER PROTEIN 467", "score" : 1197.9, "model-ac" : "PTHR24376" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 862, "end" : 887, "hmmStart" : 7, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 2.2E-11, "score" : 45.3, "envelopeStart" : 859, "envelopeEnd" : 892, "postProcessed" : true, "location-fragments" : [ { "start" : 862, "end" : 887, "dc-status" : "CONTINUOUS" } ] }, { "start" : 332, "end" : 360, "hmmStart" : 6, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 5.5E-13, "score" : 50.5, "envelopeStart" : 328, "envelopeEnd" : 363, "postProcessed" : true, "location-fragments" : [ { "start" : 332, "end" : 360, "dc-status" : "CONTINUOUS" } ] }, { "start" : 694, "end" : 720, "hmmStart" : 7, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 1.5E-12, "score" : 49.1, "envelopeStart" : 691, "envelopeEnd" : 724, "postProcessed" : true, "location-fragments" : [ { "start" : 694, "end" : 720, "dc-status" : "CONTINUOUS" } ] }, { "start" : 805, "end" : 833, "hmmStart" : 7, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 6.0E-15, "score" : 56.7, "envelopeStart" : 803, "envelopeEnd" : 836, "postProcessed" : true, "location-fragments" : [ { "start" : 805, "end" : 833, "dc-status" : "CONTINUOUS" } ] }, { "start" : 834, "end" : 861, "hmmStart" : 7, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 3.0E-12, "score" : 48.1, "envelopeStart" : 830, "envelopeEnd" : 864, "postProcessed" : true, "location-fragments" : [ { "start" : 834, "end" : 861, "dc-status" : "CONTINUOUS" } ] }, { "start" : 501, "end" : 526, "hmmStart" : 7, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 4.8E-14, "score" : 53.8, "envelopeStart" : 498, "envelopeEnd" : 531, "postProcessed" : true, "location-fragments" : [ { "start" : 501, "end" : 526, "dc-status" : "CONTINUOUS" } ] }, { "start" : 661, "end" : 693, "hmmStart" : 6, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.5E-13, "score" : 51.1, "envelopeStart" : 661, "envelopeEnd" : 696, "postProcessed" : true, "location-fragments" : [ { "start" : 661, "end" : 693, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.5E-252, "score" : 814.8, "model-ac" : "2emyA00" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 753, "end" : 780, "score" : 15.417, "alignment" : "FRCNHCSSSFSSKDFIKVHMRTHTGEKP", "location-fragments" : [ { "start" : 753, "end" : 780, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 755, "end" : 775, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CnhCsssFsskdfikvHmrtH", "location-fragments" : [ { "start" : 755, "end" : 775, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PTHR24376", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 401, "end" : 659, "hmmStart" : 373, "hmmEnd" : 642, "hmmLength" : 679, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 401, "envelopeEnd" : 660, "location-fragments" : [ { "start" : 401, "end" : 659, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "ZINC FINGER PROTEIN 467", "score" : 1197.9, "model-ac" : "PTHR24376" }, { "signature" : { "accession" : "SM00355", "name" : "c2h2final6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 753, "end" : 775, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.0056, "score" : 25.9, "location-fragments" : [ { "start" : 753, "end" : 775, "dc-status" : "CONTINUOUS" } ] }, { "start" : 392, "end" : 414, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.016, "score" : 24.4, "location-fragments" : [ { "start" : 392, "end" : 414, "dc-status" : "CONTINUOUS" } ] }, { "start" : 605, "end" : 627, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.0057, "score" : 25.9, "location-fragments" : [ { "start" : 605, "end" : 627, "dc-status" : "CONTINUOUS" } ] }, { "start" : 560, "end" : 582, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.0091, "score" : 25.2, "location-fragments" : [ { "start" : 560, "end" : 582, "dc-status" : "CONTINUOUS" } ] }, { "start" : 308, "end" : 330, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.1, "score" : 21.7, "location-fragments" : [ { "start" : 308, "end" : 330, "dc-status" : "CONTINUOUS" } ] }, { "start" : 364, "end" : 386, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.0021, "score" : 27.3, "location-fragments" : [ { "start" : 364, "end" : 386, "dc-status" : "CONTINUOUS" } ] }, { "start" : 223, "end" : 245, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.025, "score" : 23.7, "location-fragments" : [ { "start" : 223, "end" : 245, "dc-status" : "CONTINUOUS" } ] }, { "start" : 504, "end" : 526, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.026, "score" : 23.7, "location-fragments" : [ { "start" : 504, "end" : 526, "dc-status" : "CONTINUOUS" } ] }, { "start" : 476, "end" : 498, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 6.7E-4, "score" : 29.0, "location-fragments" : [ { "start" : 476, "end" : 498, "dc-status" : "CONTINUOUS" } ] }, { "start" : 837, "end" : 859, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.44, "score" : 19.6, "location-fragments" : [ { "start" : 837, "end" : 859, "dc-status" : "CONTINUOUS" } ] }, { "start" : 532, "end" : 554, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.04, "score" : 23.1, "location-fragments" : [ { "start" : 532, "end" : 554, "dc-status" : "CONTINUOUS" } ] }, { "start" : 251, "end" : 273, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 7.0, "score" : 14.6, "location-fragments" : [ { "start" : 251, "end" : 273, "dc-status" : "CONTINUOUS" } ] }, { "start" : 633, "end" : 655, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.0068, "score" : 25.6, "location-fragments" : [ { "start" : 633, "end" : 655, "dc-status" : "CONTINUOUS" } ] }, { "start" : 420, "end" : 442, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.04, "score" : 23.1, "location-fragments" : [ { "start" : 420, "end" : 442, "dc-status" : "CONTINUOUS" } ] }, { "start" : 697, "end" : 719, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 5.0E-4, "score" : 29.4, "location-fragments" : [ { "start" : 697, "end" : 719, "dc-status" : "CONTINUOUS" } ] }, { "start" : 809, "end" : 831, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.0031, "score" : 26.8, "location-fragments" : [ { "start" : 809, "end" : 831, "dc-status" : "CONTINUOUS" } ] }, { "start" : 336, "end" : 358, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.076, "score" : 22.1, "location-fragments" : [ { "start" : 336, "end" : 358, "dc-status" : "CONTINUOUS" } ] }, { "start" : 865, "end" : 887, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.22, "score" : 20.6, "location-fragments" : [ { "start" : 865, "end" : 887, "dc-status" : "CONTINUOUS" } ] }, { "start" : 725, "end" : 747, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.079, "score" : 22.1, "location-fragments" : [ { "start" : 725, "end" : 747, "dc-status" : "CONTINUOUS" } ] }, { "start" : 781, "end" : 803, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.024, "score" : 23.8, "location-fragments" : [ { "start" : 781, "end" : 803, "dc-status" : "CONTINUOUS" } ] }, { "start" : 669, "end" : 691, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.053, "score" : 22.7, "location-fragments" : [ { "start" : 669, "end" : 691, "dc-status" : "CONTINUOUS" } ] }, { "start" : 448, "end" : 470, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.04, "score" : 23.1, "location-fragments" : [ { "start" : 448, "end" : 470, "dc-status" : "CONTINUOUS" } ] }, { "start" : 280, "end" : 302, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.0071, "score" : 25.6, "location-fragments" : [ { "start" : 280, "end" : 302, "dc-status" : "CONTINUOUS" } ] }, { "start" : 893, "end" : 912, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 290.0, "score" : 0.3, "location-fragments" : [ { "start" : 893, "end" : 912, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-160, "score" : 549.0, "model-ac" : "SM00355" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 42, "end" : 101, "location-fragments" : [ { "start" : 42, "end" : 101, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 633, "end" : 660, "score" : 14.565, "alignment" : "FSCSHCSSSFSIKKNLKTHMRTHTGEKV", "location-fragments" : [ { "start" : 633, "end" : 660, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 506, "end" : 526, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCsssFlrkihlkmHmrtH", "location-fragments" : [ { "start" : 506, "end" : 526, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 282, "end" : 302, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CnpCsssFsskddlkmHmrtH", "location-fragments" : [ { "start" : 282, "end" : 302, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 783, "end" : 803, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCtacFshknslteHvrtH", "location-fragments" : [ { "start" : 783, "end" : 803, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 607, "end" : 627, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 36, "hmmBounds" : "INCOMPLETE", "evalue" : 3.0E-13, "score" : 51.3, "envelopeStart" : 603, "envelopeEnd" : 632, "postProcessed" : true, "location-fragments" : [ { "start" : 607, "end" : 627, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-223, "score" : 724.5, "model-ac" : "2ytqA01" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 225, "end" : 245, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CgeClslFssesalitHmqtH", "location-fragments" : [ { "start" : 225, "end" : 245, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 817, "end" : 874, "hmmLength" : 61, "location-fragments" : [ { "start" : 817, "end" : 874, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.59E-17, "model-ac" : "0050784" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 555, "end" : 592, "hmmStart" : 4, "hmmEnd" : 43, "hmmLength" : 59, "hmmBounds" : "INCOMPLETE", "evalue" : 6.7E-15, "score" : 56.9, "envelopeStart" : 552, "envelopeEnd" : 596, "postProcessed" : true, "location-fragments" : [ { "start" : 555, "end" : 592, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-291, "score" : 942.2, "model-ac" : "2lvhA00" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 478, "end" : 498, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CnhCsssFsskdylkvHmrtH", "location-fragments" : [ { "start" : 478, "end" : 498, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 697, "end" : 724, "score" : 15.251, "alignment" : "FSCNHCSSSFSSKKSLKKHMQTHTSEKP", "location-fragments" : [ { "start" : 697, "end" : 724, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 280, "end" : 306, "hmmStart" : 4, "hmmEnd" : 33, "hmmLength" : 38, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.0E-11, "score" : 44.3, "envelopeStart" : 280, "envelopeEnd" : 311, "postProcessed" : true, "location-fragments" : [ { "start" : 280, "end" : 306, "dc-status" : "CONTINUOUS" } ] }, { "start" : 593, "end" : 606, "hmmStart" : 17, "hmmEnd" : 33, "hmmLength" : 38, "hmmBounds" : "INCOMPLETE", "evalue" : 2.0E-5, "score" : 26.3, "envelopeStart" : 591, "envelopeEnd" : 609, "postProcessed" : true, "location-fragments" : [ { "start" : 593, "end" : 606, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-220, "score" : 715.0, "model-ac" : "2eprA01" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 280, "end" : 307, "score" : 15.417, "alignment" : "LSCNPCSSSFSSKDDLKMHMRTHTGEKP", "location-fragments" : [ { "start" : 280, "end" : 307, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 541, "end" : 591, "hmmLength" : 61, "location-fragments" : [ { "start" : 541, "end" : 591, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.79E-18, "model-ac" : "0050784" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 811, "end" : 831, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CnhCsssFsiknslkkHmrtH", "location-fragments" : [ { "start" : 811, "end" : 831, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 120, "end" : 134, "location-fragments" : [ { "start" : 120, "end" : 134, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 663, "end" : 715, "hmmLength" : 53, "location-fragments" : [ { "start" : 663, "end" : 715, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.77E-15, "model-ac" : "0053891" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 669, "end" : 696, "score" : 15.5, "alignment" : "FSCSHCRACFSHKKSLTEHVRTHTGEKP", "location-fragments" : [ { "start" : 669, "end" : 696, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PF00096", "name" : "zf-C2H2", "description" : "Zinc finger, C2H2 type", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 476, "end" : 498, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 3.5E-4, "score" : 20.9, "envelopeStart" : 476, "envelopeEnd" : 498, "postProcessed" : true, "location-fragments" : [ { "start" : 476, "end" : 498, "dc-status" : "CONTINUOUS" } ] }, { "start" : 753, "end" : 775, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.012, "score" : 16.0, "envelopeStart" : 753, "envelopeEnd" : 775, "postProcessed" : true, "location-fragments" : [ { "start" : 753, "end" : 775, "dc-status" : "CONTINUOUS" } ] }, { "start" : 364, "end" : 386, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-4, "score" : 21.3, "envelopeStart" : 364, "envelopeEnd" : 386, "postProcessed" : true, "location-fragments" : [ { "start" : 364, "end" : 386, "dc-status" : "CONTINUOUS" } ] }, { "start" : 605, "end" : 627, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.0013, "score" : 19.0, "envelopeStart" : 605, "envelopeEnd" : 627, "postProcessed" : true, "location-fragments" : [ { "start" : 605, "end" : 627, "dc-status" : "CONTINUOUS" } ] }, { "start" : 560, "end" : 582, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.014, "score" : 15.8, "envelopeStart" : 560, "envelopeEnd" : 582, "postProcessed" : true, "location-fragments" : [ { "start" : 560, "end" : 582, "dc-status" : "CONTINUOUS" } ] }, { "start" : 633, "end" : 655, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.009, "score" : 16.4, "envelopeStart" : 633, "envelopeEnd" : 655, "postProcessed" : true, "location-fragments" : [ { "start" : 633, "end" : 655, "dc-status" : "CONTINUOUS" } ] }, { "start" : 809, "end" : 831, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.0076, "score" : 16.7, "envelopeStart" : 809, "envelopeEnd" : 831, "postProcessed" : true, "location-fragments" : [ { "start" : 809, "end" : 831, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-57, "score" : 189.4, "model-ac" : "PF00096" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 837, "end" : 864, "score" : 14.378, "alignment" : "FSCSHCMACFAQKHTLTEHVRTHTGAKP", "location-fragments" : [ { "start" : 837, "end" : 864, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 141, "location-fragments" : [ { "start" : 1, "end" : 141, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 562, "end" : 582, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CnhCsssFsikinlkmHmrtH", "location-fragments" : [ { "start" : 562, "end" : 582, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 338, "end" : 358, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCtacFshkksltaHvrtH", "location-fragments" : [ { "start" : 338, "end" : 358, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 635, "end" : 655, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCsssFsikknlktHmrtH", "location-fragments" : [ { "start" : 635, "end" : 655, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 372, "end" : 429, "hmmLength" : 61, "location-fragments" : [ { "start" : 372, "end" : 429, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.21E-20, "model-ac" : "0050784" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 727, "end" : 747, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCtacFshkkslteHvraH", "location-fragments" : [ { "start" : 727, "end" : 747, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 725, "end" : 752, "score" : 15.23, "alignment" : "FSCSHCTACFSHKKSLTEHVRAHTGEKP", "location-fragments" : [ { "start" : 725, "end" : 752, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 476, "end" : 503, "score" : 16.103, "alignment" : "FSCNHCSSSFSSKDYLKVHMRTHTGEKP", "location-fragments" : [ { "start" : 476, "end" : 503, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" } ], "xref" : [ { "name" : "XP_018910215.1 PREDICTED: zinc finger protein 271-like [Bemisia tabaci]", "id" : "XP_018910215.1" } ] },{ "sequence" : "MVITSSLVVLFYAGGPLDIIRVVRSMMHLIGAVILLFNIFSKTILAERTPRSIKAQLDLFDVVPDVINTYPESECEVIYSCMNCPEDGRVVDFGTEIHPIETQVEPSVEWPADPHLNYALILVDPDVPSKEVPTMREWQHWLVVNIPGIDFMSGKVLTEYQGAAPPNGTGPHRYVFSVYQQPRKNMTFDEPKIEKRSDKNRSMFSTRRFADEYKLGDPIAVNFFMSEYNYPPRKPGE", "md5" : "2b533b1460bc1c66b53e0196bd6343e2", "matches" : [ { "signature" : { "accession" : "PS01220", "name" : "PBP", "description" : "Phosphatidylethanolamine-binding protein family signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR001858", "name" : "Phosphatidylethanolamine-bd_CS", "description" : "Phosphatidylethanolamine-binding, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 118, "end" : 140, "level" : "STRONG", "cigarAlignment" : "1M1I2M1I4M1I2M10I1M", "alignment" : "YaLIlVDPDvPSkevptmrewqH", "location-fragments" : [ { "start" : 118, "end" : 140, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01220" }, { "signature" : { "accession" : "PTHR11362:SF28", "name" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 61, "end" : 231, "hmmStart" : 16, "hmmEnd" : 179, "hmmLength" : 193, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 48, "envelopeEnd" : 236, "location-fragments" : [ { "start" : 61, "end" : 231, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-53, "familyName" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "score" : 184.3, "model-ac" : "PTHR11362:SF28" }, { "signature" : { "accession" : "PF01161", "name" : "PBP", "description" : "Phosphatidylethanolamine-binding protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR008914", "name" : "PEBP", "description" : "Phosphatidylethanolamine-binding protein", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 102, "end" : 223, "hmmStart" : 9, "hmmEnd" : 132, "hmmLength" : 132, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.2E-19, "score" : 70.1, "envelopeStart" : 92, "envelopeEnd" : 223, "postProcessed" : true, "location-fragments" : [ { "start" : 102, "end" : 223, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-19, "score" : 70.6, "model-ac" : "PF01161" }, { "signature" : { "accession" : "SSF49777", "name" : "PEBP-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 57, "end" : 229, "hmmLength" : 185, "location-fragments" : [ { "start" : 57, "end" : 229, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.42E-46, "model-ac" : "0034862" }, { "signature" : { "accession" : "G3DSA:3.90.280.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 53, "end" : 231, "hmmStart" : 14, "hmmEnd" : 176, "hmmLength" : 190, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-55, "score" : 189.6, "envelopeStart" : 53, "envelopeEnd" : 231, "postProcessed" : true, "location-fragments" : [ { "start" : 53, "end" : 231, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-55, "score" : 190.0, "model-ac" : "2iqyA00" }, { "signature" : { "accession" : "cd00866", "name" : "PEBP_euk", "description" : "PEBP_euk", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR035810", "name" : "PEBP_euk", "description" : "Phosphatidylethanolamine-binding protein, eukaryotic", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 87, "end" : 226, "sites" : [ { "description" : "substrate binding site", "numLocations" : 9, "siteLocations" : [ { "start" : 140, "end" : 140, "residue" : "H" }, { "start" : 172, "end" : 172, "residue" : "H" }, { "start" : 163, "end" : 163, "residue" : "A" }, { "start" : 165, "end" : 165, "residue" : "P" }, { "start" : 124, "end" : 124, "residue" : "D" }, { "start" : 138, "end" : 138, "residue" : "W" }, { "start" : 166, "end" : 166, "residue" : "P" }, { "start" : 164, "end" : 164, "residue" : "A" }, { "start" : 174, "end" : 174, "residue" : "Y" } ] } ], "evalue" : 1.2196E-48, "score" : 155.224, "location-fragments" : [ { "start" : 87, "end" : 226, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00866" }, { "signature" : { "accession" : "PTHR11362", "name" : "PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR035810", "name" : "PEBP_euk", "description" : "Phosphatidylethanolamine-binding protein, eukaryotic", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 61, "end" : 231, "hmmStart" : 16, "hmmEnd" : 179, "hmmLength" : 193, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 48, "envelopeEnd" : 236, "location-fragments" : [ { "start" : 61, "end" : 231, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-53, "familyName" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "score" : 184.3, "model-ac" : "PTHR11362" } ], "xref" : [ { "name" : "XP_018909664.1 PREDICTED: protein D3-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909664.1" } ] },{ "sequence" : "MAYQEDFNTFVGGLTGAFKGIKVTRKGKIIIKNLQNTKHLSNKNQITALNWGDDAERDILMGLSDQSVKVYDTEHKQFISSFEAKHGKGPIIGLAKFNRHILAGYKSGDVKFLNCDNHKMMRTEWRVGPSLDSMKVKKHLMATGGEENQLKLWDLNSTKLIYHAKNVKPDFLDLKVPVFISDIGFFPSNDKIVYCSKHGHVRIHDPSVSQKRPVLDMSVKSNNGDPHVLTALAIAPMREQHVVVGSAAGQMSLLDLRHKGIPIKKYKSFRGSIKAIAVPETEPIILTVSLDRFFRIHNMFNHGLRYQQYFQSRLSSILIRSDFSMSSKGTKEDVEILD", "md5" : "7785c916a8451a7d7ce0740991587bb5", "matches" : [ { "signature" : { "accession" : "SSF50978", "name" : "WD40 repeat-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036322", "name" : "WD40_repeat_dom_sf", "description" : "WD40-repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 34, "end" : 304, "hmmLength" : 393, "location-fragments" : [ { "start" : 34, "end" : 304, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.93E-28, "model-ac" : "0049440" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 175, "end" : 327, "hmmStart" : 211, "hmmEnd" : 327, "hmmLength" : 401, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 9.5E-11, "score" : 43.3, "envelopeStart" : 174, "envelopeEnd" : 327, "postProcessed" : true, "location-fragments" : [ { "start" : 175, "end" : 327, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-23, "score" : 84.3, "model-ac" : "4pswB00" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 23, "end" : 174, "hmmStart" : 40, "hmmEnd" : 184, "hmmLength" : 342, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 7.5E-13, "score" : 50.2, "envelopeStart" : 23, "envelopeEnd" : 175, "postProcessed" : true, "location-fragments" : [ { "start" : 23, "end" : 174, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-25, "score" : 91.9, "model-ac" : "1yfqA00" }, { "signature" : { "accession" : "PTHR16038", "name" : "NOP SEVEN ASSOCIATED PROTEIN 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR037379", "name" : "WDR74/Nsa1", "description" : "WDR74/Nsa1", "type" : "FAMILY", "goXRefs" : [ { "name" : "nucleolus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005730" }, { "name" : "ribosomal large subunit biogenesis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0042273" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 334, "hmmStart" : 15, "hmmEnd" : 357, "hmmLength" : 453, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 337, "location-fragments" : [ { "start" : 7, "end" : 334, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-70, "familyName" : "NOP SEVEN ASSOCIATED PROTEIN 1", "score" : 239.7, "model-ac" : "PTHR16038" }, { "signature" : { "accession" : "PS50294", "name" : "WD_REPEATS_REGION", "description" : "Trp-Asp (WD) repeats circular profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR017986", "name" : "WD40_repeat_dom", "description" : "WD40-repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 39, "end" : 163, "score" : 9.283, "alignment" : "HLSNKNQITALNWGDDaERDILMGLSDQSVKVYDTEHKQFISSFEAKHGKGPIIGLAKFNRHILAGYKSGDVKFLNCDNHKMMRTEWRVGPSLDSMKVKKH--LMATGGEENQLKLWDLNSTKLIYH", "location-fragments" : [ { "start" : 39, "end" : 163, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50294" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 140, "end" : 163, "score" : 8.771, "alignment" : "------------------LMATGGEENQLKLWDLNSTKLIYH", "location-fragments" : [ { "start" : 140, "end" : 163, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "SM00320", "name" : "WD40_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 215, "end" : 255, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 170.0, "score" : 2.9, "location-fragments" : [ { "start" : 215, "end" : 255, "dc-status" : "CONTINUOUS" } ] }, { "start" : 33, "end" : 72, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 15.0, "score" : 9.5, "location-fragments" : [ { "start" : 33, "end" : 72, "dc-status" : "CONTINUOUS" } ] }, { "start" : 170, "end" : 205, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 110.0, "score" : 4.2, "location-fragments" : [ { "start" : 170, "end" : 205, "dc-status" : "CONTINUOUS" } ] }, { "start" : 259, "end" : 298, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 2.6, "score" : 14.4, "location-fragments" : [ { "start" : 259, "end" : 298, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-4, "score" : 31.0, "model-ac" : "SM00320" } ], "xref" : [ { "name" : "XP_018909733.1 PREDICTED: WD repeat-containing protein 74 [Bemisia tabaci]", "id" : "XP_018909733.1" } ] },{ "sequence" : "MEETASSSNTKVSNDSAYSTCSNSQSRRSGSSKSHSHHSTTSSTSSGYGGHPSSSTLGSGSNDQLFPEPAKKSKVKDHKKKKIKSSNTTSSSTVPTPPTSTPTINEATSSEELSASSQVKSTPVAAELAEKSAATLECPQKTGKTREVVQDRRKLRSHPDSVLSSIINNGATPSAENESLQMAALSQTLLCFKKMKNKELHPPDLQTSNIDEEQFIRSNQKNDESFKSYVETSVKEKEFCVVVSMHDGIVLYTSSGLTDVLGFHKDMWLGRSFTDFVHPKDRIAFVSHVTSGVTKPFLDNQFSADASSSSKHNAKNSTFYCHLRCYRGLKSSGFNIIDRDVKYIACQFTLSFKEIVANSESSCFLNSPHGIFSVINVQPVFSAYTSSNEVINSPKFMTRHSANGVFCHVDSLVVSYLGYLPQDMMNHSIFNFYCSEDLPMLRDVYKEVMSEQGHLVASKPYKFKCQNGSFAVIETEWSTFINPWTKNLEFVIGQHKVIQGPADVDVTVPSKTEDSTPETDSQAELLKKEILEILQKPVNASNRVVKVQVSKRCRDLASFIETLVEEITKPETKNDTQKDANVSERDSVMLGEISPHHEYGSKVSSETPPSYTQLNYNENIQRFFQSQPKTSFSDRTSENKIMNSTPETSEGNEESSSSNPSNSKDRPCENVQSASSSSRSSKGSSRNAKTYKKSKINYQPPPLTEEMLSRHNEDMEKQMVINHRAQRGKMLKVKAKPQDRVGDAHGVKRSGSHSWDNGPYRRSMKQIHGNDQPHDTNRQSNRRSVVTVTMQSSIGNAYNPPEPSSISNFTYWPMFSYNGPMLQHMDHNESVPTSVPAVMGPGMHPGLAPGMPAVMPVSTPSSLPPYYIPREQQIRPEHAGPPFPPFTYIATNQAHVMSPMIHPNWPGYSPMFYAPCPVIPPLSNLGSKSGMTPSSDFNRPVSRATSVKAEPGSARSSFILMQSDASKKGGHLSVSPNNYNSNVFPGGKDNAPGGKEESGEFSFSETGDESSYYSSFYSFLKTEEKMDDSMRSSSGDDVKKYEDELWGILNGTNDDEGKKCLRRGPTWLEGVDITPELQFRYQISTKGISDVLQADMKALAKLNQPDMVNEQLSTLYLELEGIYNSLKLEDSSSSGEEGTSNKPRKRKPFNYDKMVMIFEEEAPLPPPVTTAIPVSVTVTASGN", "md5" : "fc7aa8f11dd5a656b4f50d445873a694", "matches" : [ { "signature" : { "accession" : "cd00130", "name" : "PAS", "description" : "PAS", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 393, "end" : 497, "sites" : [ { "description" : "heme pocket", "numLocations" : 7, "siteLocations" : [ { "start" : 475, "end" : 475, "residue" : "T" }, { "start" : 429, "end" : 429, "residue" : "I" }, { "start" : 444, "end" : 444, "residue" : "V" }, { "start" : 445, "end" : 445, "residue" : "Y" }, { "start" : 477, "end" : 477, "residue" : "W" }, { "start" : 441, "end" : 441, "residue" : "L" }, { "start" : 433, "end" : 433, "residue" : "Y" } ] }, { "description" : "putative active site", "numLocations" : 9, "siteLocations" : [ { "start" : 435, "end" : 435, "residue" : "S" }, { "start" : 468, "end" : 468, "residue" : "G" }, { "start" : 409, "end" : 409, "residue" : "V" }, { "start" : 463, "end" : 463, "residue" : "F" }, { "start" : 434, "end" : 434, "residue" : "C" }, { "start" : 419, "end" : 419, "residue" : "Y" }, { "start" : 413, "end" : 413, "residue" : "V" }, { "start" : 432, "end" : 432, "residue" : "F" }, { "start" : 433, "end" : 433, "residue" : "Y" } ] } ], "evalue" : 1.61756E-7, "score" : 48.7835, "location-fragments" : [ { "start" : 393, "end" : 497, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00130" }, { "signature" : { "accession" : "PS50112", "name" : "PAS", "description" : "PAS repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 401, "end" : 452, "score" : 10.168, "alignment" : "-------------------SANGVFCHVDSLVVSYLGYLPQDMMNHS-IFNFYCSEDLPMLRDVYKEVMSEQ", "location-fragments" : [ { "start" : 401, "end" : 452, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50112" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 86, "end" : 122, "location-fragments" : [ { "start" : 86, "end" : 122, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF14598", "name" : "PAS_11", "description" : "PAS domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 395, "end" : 499, "hmmStart" : 3, "hmmEnd" : 109, "hmmLength" : 113, "hmmBounds" : "INCOMPLETE", "evalue" : 1.9E-11, "score" : 44.0, "envelopeStart" : 393, "envelopeEnd" : 502, "postProcessed" : true, "location-fragments" : [ { "start" : 395, "end" : 499, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-14, "score" : 54.4, "model-ac" : "PF14598" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 571, "end" : 706, "location-fragments" : [ { "start" : 571, "end" : 706, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.450.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 381, "end" : 539, "hmmStart" : 2, "hmmEnd" : 157, "hmmLength" : 158, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-42, "score" : 146.1, "envelopeStart" : 381, "envelopeEnd" : 539, "postProcessed" : true, "location-fragments" : [ { "start" : 381, "end" : 539, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-52, "score" : 179.3, "model-ac" : "4dj2B02" }, { "signature" : { "accession" : "PTHR11269:SF16", "name" : "PERIOD CIRCADIAN PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 1167, "hmmStart" : 8, "hmmEnd" : 1196, "hmmLength" : 1203, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 1171, "location-fragments" : [ { "start" : 5, "end" : 1167, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-224, "familyName" : "PERIOD CIRCADIAN PROTEIN", "score" : 749.7, "model-ac" : "PTHR11269:SF16" }, { "signature" : { "accession" : "SM00091", "name" : "pas_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 384, "end" : 450, "hmmStart" : 1, "hmmEnd" : 68, "hmmLength" : 68, "hmmBounds" : "COMPLETE", "evalue" : 0.18, "score" : 20.9, "location-fragments" : [ { "start" : 384, "end" : 450, "dc-status" : "CONTINUOUS" } ] }, { "start" : 224, "end" : 294, "hmmStart" : 1, "hmmEnd" : 68, "hmmLength" : 68, "hmmBounds" : "COMPLETE", "evalue" : 0.0034, "score" : 26.6, "location-fragments" : [ { "start" : 224, "end" : 294, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-9, "score" : 47.5, "model-ac" : "SM00091" }, { "signature" : { "accession" : "PS50112", "name" : "PAS", "description" : "PAS repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 247, "end" : 282, "score" : 10.908, "alignment" : "---------------------DGIVLYTSSGLTDVLGFHKDMWLGRS-FTDFVHPKDR--------------", "location-fragments" : [ { "start" : 247, "end" : 282, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50112" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 600, "end" : 694, "location-fragments" : [ { "start" : 600, "end" : 694, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF55785", "name" : "PYP-like sensor domain (PAS domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035965", "name" : "PAS-like_dom_sf", "description" : "PAS domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 394, "end" : 498, "hmmLength" : 109, "location-fragments" : [ { "start" : 394, "end" : 498, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.68E-21, "model-ac" : "0048579" }, { "signature" : { "accession" : "cd00130", "name" : "PAS", "description" : "PAS", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 241, "end" : 285, "sites" : [ ], "evalue" : 2.70415E-5, "score" : 42.2351, "location-fragments" : [ { "start" : 241, "end" : 285, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00130" }, { "signature" : { "accession" : "G3DSA:3.30.450.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 235, "end" : 380, "hmmStart" : 4, "hmmEnd" : 138, "hmmLength" : 138, "hmmBounds" : "COMPLETE", "evalue" : 1.0E-35, "score" : 124.9, "envelopeStart" : 235, "envelopeEnd" : 380, "postProcessed" : true, "location-fragments" : [ { "start" : 235, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-40, "score" : 138.8, "model-ac" : "3rtyB01" }, { "signature" : { "accession" : "G3DSA:1.20.5.770", "name" : "Single helix bin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 542, "end" : 575, "hmmStart" : 4, "hmmEnd" : 32, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 6.3E-10, "score" : 40.5, "envelopeStart" : 542, "envelopeEnd" : 575, "postProcessed" : true, "location-fragments" : [ { "start" : 542, "end" : 575, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-10, "score" : 41.5, "model-ac" : "1wa9B03" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 742, "end" : 784, "location-fragments" : [ { "start" : 742, "end" : 784, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 122, "location-fragments" : [ { "start" : 1, "end" : 122, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 63, "location-fragments" : [ { "start" : 1, "end" : 63, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 984, "end" : 1004, "location-fragments" : [ { "start" : 984, "end" : 1004, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF55785", "name" : "PYP-like sensor domain (PAS domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035965", "name" : "PAS-like_dom_sf", "description" : "PAS domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 238, "end" : 289, "hmmLength" : 109, "location-fragments" : [ { "start" : 238, "end" : 289, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.08E-8, "model-ac" : "0048579" }, { "signature" : { "accession" : "PF12114", "name" : "Period_C", "description" : "Period protein 2/3C-terminal region", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022728", "name" : "Period_circadian-like_C", "description" : "Period circadian-like, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1000, "end" : 1143, "hmmStart" : 48, "hmmEnd" : 185, "hmmLength" : 195, "hmmBounds" : "INCOMPLETE", "evalue" : 2.7E-14, "score" : 53.2, "envelopeStart" : 952, "envelopeEnd" : 1154, "postProcessed" : true, "location-fragments" : [ { "start" : 1000, "end" : 1143, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-14, "score" : 53.2, "model-ac" : "PF12114" }, { "signature" : { "accession" : "PTHR11269", "name" : "PERIOD CIRCADIAN PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 1167, "hmmStart" : 8, "hmmEnd" : 1196, "hmmLength" : 1203, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 1171, "location-fragments" : [ { "start" : 5, "end" : 1167, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-224, "familyName" : "PERIOD CIRCADIAN PROTEIN", "score" : 749.7, "model-ac" : "PTHR11269" } ], "xref" : [ { "name" : "XP_018910230.1 PREDICTED: period circadian protein isoform X1 [Bemisia tabaci]", "id" : "XP_018910230.1" } ] },{ "sequence" : "MAIQNSLIIFAKNVDSIWARTMSTRLSANINRKNNNDDEDDEDCDIGTGEEGADKQKEKAKKKKKRTFNVEEFKLLPFLNTDKNIDMKLDKKEDKLAKQSAKLVLPTSLNTKSG", "md5" : "85ce00a0eb8f2efac2bd451dcd6eec43", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 29, "end" : 61, "location-fragments" : [ { "start" : 29, "end" : 61, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909961.1 PREDICTED: uncharacterized protein LOC109039080 [Bemisia tabaci]", "id" : "XP_018909961.1" } ] },{ "sequence" : "MFRQRSSEGSPVAPDGRDESETSKSRTSVTRSISSNNASAMNIDSTKNEPDVKEKLSNLGNVNLALLTKHLFSKEDLKEDDMPWTWDAIFTEVSSELRSQWEKSKQDGTP", "md5" : "a6524fa5108379964acbdc741b6f09ce", "matches" : [ { "signature" : { "accession" : "PTHR33724", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR029302", "name" : "IFT43", "description" : "Intraflagellar transport protein 43", "type" : "FAMILY", "goXRefs" : [ { "name" : "intraciliary transport particle A", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0030991" } ], "pathwayXRefs" : [ { "name" : "Intraflagellar transport", "databaseName" : "Reactome", "id" : "R-HSA-5620924" } ] } }, "locations" : [ { "start" : 10, "end" : 107, "hmmStart" : 100, "hmmEnd" : 197, "hmmLength" : 208, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 110, "location-fragments" : [ { "start" : 10, "end" : 107, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-15, "familyName" : "FAMILY NOT NAMED", "score" : 60.6, "model-ac" : "PTHR33724" }, { "signature" : { "accession" : "PF15305", "name" : "IFT43", "description" : "Intraflagellar transport protein 43", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR029302", "name" : "IFT43", "description" : "Intraflagellar transport protein 43", "type" : "FAMILY", "goXRefs" : [ { "name" : "intraciliary transport particle A", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0030991" } ], "pathwayXRefs" : [ { "name" : "Intraflagellar transport", "databaseName" : "Reactome", "id" : "R-HSA-5620924" } ] } }, "locations" : [ { "start" : 58, "end" : 103, "hmmStart" : 92, "hmmEnd" : 136, "hmmLength" : 136, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.8E-9, "score" : 37.9, "envelopeStart" : 8, "envelopeEnd" : 103, "postProcessed" : true, "location-fragments" : [ { "start" : 58, "end" : 103, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-10, "score" : 39.3, "model-ac" : "PF15305" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 54, "location-fragments" : [ { "start" : 1, "end" : 54, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 26, "end" : 46, "location-fragments" : [ { "start" : 26, "end" : 46, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910389.1 PREDICTED: intraflagellar transport protein 43 homolog [Bemisia tabaci]", "id" : "XP_018910389.1" } ] },{ "sequence" : "MATSNSDSEDKDSGILTNSQHSLKSVFDLVRNGSITDLDNLVDRVGPESLSSRDEWGYTPAHWAALDGNADVVRYLIQHQVPVDFPCLGIQGSRPIHWACRKGHTAVVQLLLQAGVAVNAADFKGLTPLMTACMFGRAATTAYLLGRGALHHLVDINGDTALHWAAYKGHSDVVRLLTFSGVDLQKADNFGSTPLHLACLSGNVNCVRTLCEASKLELEPRDKNGKTPLMLATSHRHNDIIECLSTVIKKRARIMPPLSEIWSLLFGGGGNSKGPLFLFLGSFLLWCYPMYVLRCIPLTWNTLRGWHYIFLYWNAVMWVCWTIANRIDPGYIPCNTETYHRIIRQIPHSDKWNKKRDGMLTRLCHTCRCVRPLRAKHCRICDRCVAHFDHHCPFIYNCVGVRNRMWFFTFVLSIAINCSLTIFFACHCLALEGFELLYVLGLSEALIFCALGWILTCSSMLHACMNLTTNEMFNYKRYSYLRDKRGKYYNVFSRGPFFNLMDFFICSGRTQLDCDLLTEEFS", "md5" : "5003b9b1121f871658f814032ef56e07", "matches" : [ { "signature" : { "accession" : "PF13857", "name" : "Ank_5", "description" : "Ankyrin repeats (many copies)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 41, "end" : 82, "hmmStart" : 1, "hmmEnd" : 41, "hmmLength" : 56, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.2E-7, "score" : 30.5, "envelopeStart" : 41, "envelopeEnd" : 87, "postProcessed" : true, "location-fragments" : [ { "start" : 41, "end" : 82, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.3E-32, "score" : 108.7, "model-ac" : "PF13857" }, { "signature" : { "accession" : "PF12796", "name" : "Ank_2", "description" : "Ankyrin repeats (3 copies)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR020683", "name" : "Ankyrin_rpt-contain_dom", "description" : "Ankyrin repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 107, "end" : 186, "hmmStart" : 12, "hmmEnd" : 81, "hmmLength" : 83, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-13, "score" : 50.9, "envelopeStart" : 107, "envelopeEnd" : 188, "postProcessed" : true, "location-fragments" : [ { "start" : 107, "end" : 186, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-40, "score" : 135.4, "model-ac" : "PF12796" }, { "signature" : { "accession" : "PS50297", "name" : "ANK_REP_REGION", "description" : "Ankyrin repeat region circular profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR020683", "name" : "Ankyrin_rpt-contain_dom", "description" : "Ankyrin repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 49, "end" : 244, "score" : 49.95, "alignment" : "--------------------------SLSSRDEWGYTPAHWAALDGNADVVRYLIQHQVPVDFPCLgiQGSRPIHWACRKGHTAVVQLLLQAGVAVNAADFKGLTPLMTACMFGRAATTAYLLGRGALHHLVDINGDTALHWAAYKGHSDVVRLLTFSGVDLQKADNFGSTPLHLACLSGNVNcVRTLCEASKLELEPRDKNGKTPLMLATSHRHNDIIECL------------", "location-fragments" : [ { "start" : 49, "end" : 244, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50297" }, { "signature" : { "accession" : "PTHR22883:SF88", "name" : "PALMITOYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 176, "end" : 520, "hmmStart" : 240, "hmmEnd" : 583, "hmmLength" : 585, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 14, "envelopeEnd" : 521, "location-fragments" : [ { "start" : 176, "end" : 520, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-146, "familyName" : "PALMITOYLTRANSFERASE", "score" : 491.3, "model-ac" : "PTHR22883:SF88" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 157, "end" : 189, "score" : 13.197, "alignment" : "NGDTALHWAAYKGHSDVVRLLTFSGVDLQKADN", "location-fragments" : [ { "start" : 157, "end" : 189, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "SSF48403", "name" : "Ankyrin repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 30, "end" : 244, "hmmLength" : 291, "location-fragments" : [ { "start" : 30, "end" : 244, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.08E-56, "model-ac" : "0049331" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 91, "end" : 123, "score" : 12.876, "alignment" : "QGSRPIHWACRKGHTAVVQLLLQAGVAVNAADF", "location-fragments" : [ { "start" : 91, "end" : 123, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "PF13637", "name" : "Ank_4", "description" : "Ankyrin repeats (many copies)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 192, "end" : 243, "hmmStart" : 2, "hmmEnd" : 53, "hmmLength" : 55, "hmmBounds" : "INCOMPLETE", "evalue" : 1.0E-4, "score" : 22.8, "envelopeStart" : 191, "envelopeEnd" : 246, "postProcessed" : true, "location-fragments" : [ { "start" : 192, "end" : 243, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-40, "score" : 135.2, "model-ac" : "PF13637" }, { "signature" : { "accession" : "PR01415", "name" : "ANKYRIN", "description" : "Ankyrin repeat signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 57, "end" : 72, "pvalue" : 4.25E-7, "score" : 38.43, "motifNumber" : 1, "location-fragments" : [ { "start" : 57, "end" : 72, "dc-status" : "CONTINUOUS" } ] }, { "start" : 107, "end" : 121, "pvalue" : 1.15E-5, "score" : 37.0, "motifNumber" : 2, "location-fragments" : [ { "start" : 107, "end" : 121, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-5, "graphscan" : "II", "model-ac" : "PR01415" }, { "signature" : { "accession" : "G3DSA:1.25.40.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 155, "end" : 253, "hmmStart" : 103, "hmmEnd" : 194, "hmmLength" : 228, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.7E-27, "score" : 98.2, "envelopeStart" : 151, "envelopeEnd" : 253, "postProcessed" : true, "location-fragments" : [ { "start" : 155, "end" : 253, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.1E-66, "score" : 223.9, "model-ac" : "2dznA00" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 190, "end" : 210, "score" : 8.897, "alignment" : "FGSTPLHLACLSGNVNCVRTL------------", "location-fragments" : [ { "start" : 190, "end" : 210, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "PS50216", "name" : "DHHC", "description" : "DHHC domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 362, "end" : 412, "score" : 23.736, "alignment" : "RLCHTCRCVRPLRAKHCRICDRCVAHFDHHCPFIYNCVGVRNRMWFFTFVL", "location-fragments" : [ { "start" : 362, "end" : 412, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50216" }, { "signature" : { "accession" : "PTHR22883", "name" : "ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 176, "end" : 520, "hmmStart" : 240, "hmmEnd" : 583, "hmmLength" : 585, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 14, "envelopeEnd" : 521, "location-fragments" : [ { "start" : 176, "end" : 520, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-146, "familyName" : "PALMITOYLTRANSFERASE", "score" : 491.3, "model-ac" : "PTHR22883" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 56, "end" : 84, "score" : 9.377, "alignment" : "WGYTPAHWAALDGNADVVRYLIQHQVPVD----", "location-fragments" : [ { "start" : 56, "end" : 84, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "PF01529", "name" : "DHHC", "description" : "DHHC palmitoyltransferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001594", "name" : "Palmitoyltrfase_DHHC", "description" : "Palmitoyltransferase, DHHC domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "palmitoyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016409" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 361, "end" : 476, "hmmStart" : 5, "hmmEnd" : 134, "hmmLength" : 134, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.2E-20, "score" : 71.9, "envelopeStart" : 358, "envelopeEnd" : 476, "postProcessed" : true, "location-fragments" : [ { "start" : 361, "end" : 476, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.2E-20, "score" : 71.9, "model-ac" : "PF01529" }, { "signature" : { "accession" : "G3DSA:1.25.40.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 19, "end" : 154, "hmmStart" : 7, "hmmEnd" : 137, "hmmLength" : 179, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.4E-31, "score" : 111.2, "envelopeStart" : 19, "envelopeEnd" : 158, "postProcessed" : true, "location-fragments" : [ { "start" : 19, "end" : 154, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-61, "score" : 208.3, "model-ac" : "4hi8A00" }, { "signature" : { "accession" : "SM00248", "name" : "ANK_2a", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 91, "end" : 120, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-4, "score" : 30.3, "location-fragments" : [ { "start" : 91, "end" : 120, "dc-status" : "CONTINUOUS" } ] }, { "start" : 190, "end" : 218, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 0.014, "score" : 24.6, "location-fragments" : [ { "start" : 190, "end" : 218, "dc-status" : "CONTINUOUS" } ] }, { "start" : 124, "end" : 153, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 2.3, "score" : 17.2, "location-fragments" : [ { "start" : 124, "end" : 153, "dc-status" : "CONTINUOUS" } ] }, { "start" : 224, "end" : 253, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 15.0, "score" : 14.5, "location-fragments" : [ { "start" : 224, "end" : 253, "dc-status" : "CONTINUOUS" } ] }, { "start" : 56, "end" : 85, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 0.001, "score" : 28.4, "location-fragments" : [ { "start" : 56, "end" : 85, "dc-status" : "CONTINUOUS" } ] }, { "start" : 157, "end" : 186, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 5.0E-5, "score" : 32.7, "location-fragments" : [ { "start" : 157, "end" : 186, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-39, "score" : 147.6, "model-ac" : "SM00248" } ], "xref" : [ { "name" : "XP_018910207.1 PREDICTED: palmitoyltransferase AKR1 isoform X1 [Bemisia tabaci]", "id" : "XP_018910207.1" }, { "name" : "XP_018910208.1 PREDICTED: palmitoyltransferase AKR1 isoform X2 [Bemisia tabaci]", "id" : "XP_018910208.1" } ] },{ "sequence" : "MLGTRPVMDWKHLAGSWIQLLTILCALSLAPSWCDSSLTCSPGIDYGVTIPRGDIILEEGQELRIRCELNVNHVEVQDKNASSLYFVRNETEVPGELVRILNESAIELLDPAPKPSDSIYSCRFHHEDRAQFPQGVGICLNRVSVGFRPGKYLVTNISCISYNWQNLTCSWTPPQNFIKTEYQIVLYEVGKRNPYYKCPETTRRENSCTWSHSTEPMYRQAIENYNITITGINSFGKHTQYLVFNSYERVLPDKPKLSVLNKTSNSILLHWQVLFPLETFPPGLIQKVEYQPRWESRDPWHTADTSSLGLRNVNYTFHLTNLKYANTHYDIRVFMKSAKVEGDSLWSEPASVTVKTLPDVPSSPPKTDVGTFEIVPRDHPHHDRDVYVYWQQIPDYSKNGDDFEYKVIEVKEAGIPRNILPTYVTKAFAKFDRISNNAHEFTIIASNRKGRSVNSSKVFVPNKLFMPSEPVSFTKVAYDQGIYELSWKASNRHHLVDNYTIFWCDNERERPYQCEGILQWIFVDQNTFIKNVTVPDITKNYQFAISANSKDGSSGMVWAKCTIIHNKVIGKMNDVWVQKVGSTSIELGWKLDCSGRIGVLQGFRIFYCPIINLQNPECTEPQQNTTVGDQSSATIHNLRPYRTYRISVAVLTISETGALSDPIYETTLEAAPEKPPMNLRLGTVTNTTAHISWDPPPPESHNGVISYYEINYSSLTYNTSLNETEALLTNLKSHKVYSVTVSACTKSCSKPSASLKFKTNIGTPGEIQQPIVRFTNSTQALVSWLPPALKGGNLDFYDIEISDDDRRNSTFIIRQANRTETLVSCPNGKTKTKEVRVRAVNTDGNMTYIGPWSSPGTVACIVSGMSPFMLGLIYIFFFTIFAGCAVWAGKTSWYRCAKMKDFDVKLPPSLNAICDDKNKEQHECSLPMQNWSGHSRKDEHAAKAESCADEELLLQKKEIGSENDDAAEDSESKHETVFQGDSPTISNSDNNHSSTKSVPKSNENYSDKKDVGEGSTSKGNSSDRDLTYCKVGGGYVSIAPISGPSSASQPAPTIIENPYVPNHFENPTVSSYVKAFNIPNPSQLYCRIGLGPPDMQTMPDAGTKLLLNPEPRYVTVGESIKLNREKNSVST", "md5" : "617d819cc2f0b85aac3db666dbc93e67", "matches" : [ { "signature" : { "accession" : "PF00041", "name" : "fn3", "description" : "Fibronectin type III domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR003961", "name" : "FN3_dom", "description" : "Fibronectin type III", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 574, "end" : 653, "hmmStart" : 5, "hmmEnd" : 78, "hmmLength" : 85, "hmmBounds" : "INCOMPLETE", "evalue" : 2.8E-7, "score" : 30.8, "envelopeStart" : 570, "envelopeEnd" : 660, "postProcessed" : true, "location-fragments" : [ { "start" : 574, "end" : 653, "dc-status" : "CONTINUOUS" } ] }, { "start" : 675, "end" : 747, "hmmStart" : 2, "hmmEnd" : 79, "hmmLength" : 85, "hmmBounds" : "INCOMPLETE", "evalue" : 3.6E-10, "score" : 40.1, "envelopeStart" : 674, "envelopeEnd" : 752, "postProcessed" : true, "location-fragments" : [ { "start" : 675, "end" : 747, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-31, "score" : 109.0, "model-ac" : "PF00041" }, { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 154, "end" : 248, "hmmStart" : 8, "hmmEnd" : 90, "hmmLength" : 101, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-14, "score" : 56.4, "envelopeStart" : 154, "envelopeEnd" : 248, "postProcessed" : true, "location-fragments" : [ { "start" : 154, "end" : 248, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-19, "score" : 70.2, "model-ac" : "3n06B01" }, { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 763, "end" : 860, "hmmStart" : 13, "hmmEnd" : 107, "hmmLength" : 119, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.6E-8, "score" : 35.4, "envelopeStart" : 758, "envelopeEnd" : 860, "postProcessed" : true, "location-fragments" : [ { "start" : 763, "end" : 860, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-51, "score" : 175.1, "model-ac" : "2ed7A00" }, { "signature" : { "accession" : "SM00060", "name" : "FN3_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003961", "name" : "FN3_dom", "description" : "Fibronectin type III", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 467, "end" : 554, "hmmStart" : 1, "hmmEnd" : 69, "hmmLength" : 69, "hmmBounds" : "COMPLETE", "evalue" : 9.0, "score" : 11.9, "location-fragments" : [ { "start" : 467, "end" : 554, "dc-status" : "CONTINUOUS" } ] }, { "start" : 252, "end" : 342, "hmmStart" : 1, "hmmEnd" : 69, "hmmLength" : 69, "hmmBounds" : "COMPLETE", "evalue" : 0.0029, "score" : 26.8, "location-fragments" : [ { "start" : 252, "end" : 342, "dc-status" : "CONTINUOUS" } ] }, { "start" : 569, "end" : 657, "hmmStart" : 1, "hmmEnd" : 69, "hmmLength" : 69, "hmmBounds" : "COMPLETE", "evalue" : 0.16, "score" : 21.1, "location-fragments" : [ { "start" : 569, "end" : 657, "dc-status" : "CONTINUOUS" } ] }, { "start" : 672, "end" : 749, "hmmStart" : 1, "hmmEnd" : 69, "hmmLength" : 69, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-8, "score" : 44.5, "location-fragments" : [ { "start" : 672, "end" : 749, "dc-status" : "CONTINUOUS" } ] }, { "start" : 764, "end" : 846, "hmmStart" : 1, "hmmEnd" : 69, "hmmLength" : 69, "hmmBounds" : "COMPLETE", "evalue" : 13.0, "score" : 10.6, "location-fragments" : [ { "start" : 764, "end" : 846, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.7E-30, "score" : 114.9, "model-ac" : "SM00060" }, { "signature" : { "accession" : "cd00063", "name" : "FN3", "description" : "FN3", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR003961", "name" : "FN3_dom", "description" : "Fibronectin type III", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 252, "end" : 354, "sites" : [ { "description" : "Cytokine receptor motif", "numLocations" : 4, "siteLocations" : [ { "start" : 347, "end" : 347, "residue" : "S" }, { "start" : 346, "end" : 346, "residue" : "W" }, { "start" : 343, "end" : 343, "residue" : "D" }, { "start" : 344, "end" : 344, "residue" : "S" } ] }, { "description" : "Interdomain contacts", "numLocations" : 3, "siteLocations" : [ { "start" : 252, "end" : 252, "residue" : "P" }, { "start" : 325, "end" : 325, "residue" : "A" }, { "start" : 342, "end" : 342, "residue" : "G" } ] } ], "evalue" : 5.55344E-6, "score" : 44.0243, "location-fragments" : [ { "start" : 252, "end" : 354, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00063" }, { "signature" : { "accession" : "cd00063", "name" : "FN3", "description" : "FN3", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR003961", "name" : "FN3_dom", "description" : "Fibronectin type III", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 764, "end" : 858, "sites" : [ { "description" : "Interdomain contacts", "numLocations" : 3, "siteLocations" : [ { "start" : 844, "end" : 844, "residue" : "G" }, { "start" : 830, "end" : 830, "residue" : "T" }, { "start" : 764, "end" : 764, "residue" : "P" } ] }, { "description" : "Cytokine receptor motif", "numLocations" : 4, "siteLocations" : [ { "start" : 852, "end" : 852, "residue" : "W" }, { "start" : 850, "end" : 850, "residue" : "G" }, { "start" : 853, "end" : 853, "residue" : "S" }, { "start" : 849, "end" : 849, "residue" : "I" } ] } ], "evalue" : 5.99901E-7, "score" : 46.7207, "location-fragments" : [ { "start" : 764, "end" : 858, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00063" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 954, "end" : 976, "location-fragments" : [ { "start" : 954, "end" : 976, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF49265", "name" : "Fibronectin type III", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036116", "name" : "FN3_sf", "description" : "Fibronectin type III superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 155, "end" : 250, "hmmLength" : 107, "location-fragments" : [ { "start" : 155, "end" : 250, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.34E-9, "model-ac" : "0052411" }, { "signature" : { "accession" : "PS50853", "name" : "FN3", "description" : "Fibronectin type-III domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR003961", "name" : "FN3_dom", "description" : "Fibronectin type III", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 251, "end" : 359, "score" : 11.882, "alignment" : "LPDKPKLSVLNktSNSILLHWQVLFplETFPPGLIQKVEYQPRWeSRDPWHTADTSslglrnVNYTFHLTNLKYANTHYDIRVFMKSAKVEgdSLWSEPASVTvkTLPD", "location-fragments" : [ { "start" : 251, "end" : 359, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50853" }, { "signature" : { "accession" : "SSF49265", "name" : "Fibronectin type III", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036116", "name" : "FN3_sf", "description" : "Fibronectin type III superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 252, "end" : 458, "hmmLength" : 196, "location-fragments" : [ { "start" : 252, "end" : 458, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-10, "model-ac" : "0053850" }, { "signature" : { "accession" : "PS50853", "name" : "FN3", "description" : "Fibronectin type-III domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR003961", "name" : "FN3_dom", "description" : "Fibronectin type III", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 571, "end" : 670, "score" : 12.821, "alignment" : "KMNDVWVQKVGSTSIELGWKLDCsGRIGVLQGFRIFYCPIINLQNPECTEPqqnTtvGDQSSATIHNLRPYRTYRISVAVLTISETGALSDPIYETTLEA", "location-fragments" : [ { "start" : 571, "end" : 670, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50853" }, { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 671, "end" : 762, "hmmStart" : 9, "hmmEnd" : 119, "hmmLength" : 122, "hmmBounds" : "INCOMPLETE", "evalue" : 9.5E-20, "score" : 72.9, "envelopeStart" : 666, "envelopeEnd" : 766, "postProcessed" : true, "location-fragments" : [ { "start" : 671, "end" : 762, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-56, "score" : 189.3, "model-ac" : "1va9A00" }, { "signature" : { "accession" : "PTHR23036", "name" : "CYTOKINE RECEPTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 506, "end" : 924, "hmmStart" : 469, "hmmEnd" : 893, "hmmLength" : 991, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 502, "envelopeEnd" : 1023, "location-fragments" : [ { "start" : 506, "end" : 924, "dc-status" : "CONTINUOUS" } ] }, { "start" : 137, "end" : 394, "hmmStart" : 69, "hmmEnd" : 289, "hmmLength" : 991, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 131, "envelopeEnd" : 430, "location-fragments" : [ { "start" : 137, "end" : 394, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-44, "familyName" : "INTERLEUKIN 12 RECEPTOR, BETA 2A,-LIKE", "score" : 153.0, "model-ac" : "PTHR23036" }, { "signature" : { "accession" : "PF09240", "name" : "IL6Ra-bind", "description" : "Interleukin-6 receptor alpha chain, binding", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR015321", "name" : "TypeI_recpt_CBD", "description" : "Type I cytokine receptor, cytokine-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 156, "end" : 238, "hmmStart" : 1, "hmmEnd" : 84, "hmmLength" : 96, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.3E-6, "score" : 27.5, "envelopeStart" : 156, "envelopeEnd" : 247, "postProcessed" : true, "location-fragments" : [ { "start" : 156, "end" : 238, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.3E-7, "score" : 29.2, "model-ac" : "PF09240" }, { "signature" : { "accession" : "PS50853", "name" : "FN3", "description" : "Fibronectin type-III domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR003961", "name" : "FN3_dom", "description" : "Fibronectin type III", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 153, "end" : 249, "score" : 7.574, "alignment" : "LVTNISCISYNWQNLTCSWTPP--QNFIKTEYQIVLYEVGKRNPYYKCPETtRRENSCTWSHstepmyRQAIENYNITITGINSFGK--HTQYLVFNSYER", "location-fragments" : [ { "start" : 153, "end" : 249, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50853" }, { "signature" : { "accession" : "PTHR23036:SF158", "name" : "INTERLEUKIN 12 RECEPTOR, BETA 2A,-LIKE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 506, "end" : 924, "hmmStart" : 469, "hmmEnd" : 893, "hmmLength" : 991, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 502, "envelopeEnd" : 1023, "location-fragments" : [ { "start" : 506, "end" : 924, "dc-status" : "CONTINUOUS" } ] }, { "start" : 137, "end" : 394, "hmmStart" : 69, "hmmEnd" : 289, "hmmLength" : 991, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 131, "envelopeEnd" : 430, "location-fragments" : [ { "start" : 137, "end" : 394, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-44, "familyName" : "INTERLEUKIN 12 RECEPTOR, BETA 2A,-LIKE", "score" : 153.0, "model-ac" : "PTHR23036:SF158" }, { "signature" : { "accession" : "PS50853", "name" : "FN3", "description" : "Fibronectin type-III domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR003961", "name" : "FN3_dom", "description" : "Fibronectin type III", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 675, "end" : 762, "score" : 18.659, "alignment" : "PPMNLRLGTVTNTTAHISWDPPPpeSHNGVISYYEINY-------SSLTYNTSLNETEALLTNLKSHKVYSVTVSACTKSC-SKPSASLKFKTNIG", "location-fragments" : [ { "start" : 675, "end" : 762, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50853" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 977, "end" : 1001, "location-fragments" : [ { "start" : 977, "end" : 1001, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 954, "end" : 1021, "location-fragments" : [ { "start" : 954, "end" : 1021, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 565, "end" : 670, "hmmStart" : 22, "hmmEnd" : 117, "hmmLength" : 120, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.2E-14, "score" : 55.4, "envelopeStart" : 565, "envelopeEnd" : 674, "postProcessed" : true, "location-fragments" : [ { "start" : 565, "end" : 670, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.0E-42, "score" : 143.8, "model-ac" : "1ujtA00" }, { "signature" : { "accession" : "SSF49265", "name" : "Fibronectin type III", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036116", "name" : "FN3_sf", "description" : "Fibronectin type III superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 758, "end" : 857, "hmmLength" : 123, "location-fragments" : [ { "start" : 758, "end" : 857, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.38E-9, "model-ac" : "0050505" }, { "signature" : { "accession" : "SSF49265", "name" : "Fibronectin type III", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036116", "name" : "FN3_sf", "description" : "Fibronectin type III superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 574, "end" : 746, "hmmLength" : 196, "location-fragments" : [ { "start" : 574, "end" : 746, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.12E-28, "model-ac" : "0053850" }, { "signature" : { "accession" : "cd00063", "name" : "FN3", "description" : "FN3", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR003961", "name" : "FN3_dom", "description" : "Fibronectin type III", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 574, "end" : 667, "sites" : [ { "description" : "Cytokine receptor motif", "numLocations" : 4, "siteLocations" : [ { "start" : 657, "end" : 657, "residue" : "G" }, { "start" : 660, "end" : 660, "residue" : "S" }, { "start" : 659, "end" : 659, "residue" : "L" }, { "start" : 656, "end" : 656, "residue" : "T" } ] } ], "evalue" : 7.148E-8, "score" : 49.4171, "location-fragments" : [ { "start" : 574, "end" : 667, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00063" }, { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 252, "end" : 367, "hmmStart" : 3, "hmmEnd" : 108, "hmmLength" : 111, "hmmBounds" : "COMPLETE", "evalue" : 7.2E-9, "score" : 37.9, "envelopeStart" : 252, "envelopeEnd" : 367, "postProcessed" : true, "location-fragments" : [ { "start" : 252, "end" : 367, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-46, "score" : 157.8, "model-ac" : "1bquA02" }, { "signature" : { "accession" : "cd00063", "name" : "FN3", "description" : "FN3", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR003961", "name" : "FN3_dom", "description" : "Fibronectin type III", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 675, "end" : 759, "sites" : [ { "description" : "Cytokine receptor motif", "numLocations" : 4, "siteLocations" : [ { "start" : 748, "end" : 748, "residue" : "C" }, { "start" : 749, "end" : 749, "residue" : "S" }, { "start" : 751, "end" : 751, "residue" : "P" }, { "start" : 752, "end" : 752, "residue" : "S" } ] } ], "evalue" : 2.92818E-12, "score" : 61.7435, "location-fragments" : [ { "start" : 675, "end" : 759, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00063" }, { "signature" : { "accession" : "PS50853", "name" : "FN3", "description" : "Fibronectin type-III domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR003961", "name" : "FN3_dom", "description" : "Fibronectin type III", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 763, "end" : 864, "score" : 12.576, "alignment" : "TPGEIQqpiVRFTNSTQALVSWLPPALKGGNLDFYDIEISDDDRRNSTFIIRQaNRTETLVSCPN-GKTKTKEVRVRAVNTDGNmtyiGPWSSPGTVAcIVSG", "location-fragments" : [ { "start" : 763, "end" : 864, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50853" }, { "signature" : { "accession" : "SSF49265", "name" : "Fibronectin type III", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036116", "name" : "FN3_sf", "description" : "Fibronectin type III superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 467, "end" : 555, "hmmLength" : 107, "location-fragments" : [ { "start" : 467, "end" : 555, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.66E-5, "model-ac" : "0035921" } ], "xref" : [ { "name" : "XP_018910513.1 PREDICTED: cytokine receptor [Bemisia tabaci]", "id" : "XP_018910513.1" } ] },{ "sequence" : "MKLLTFVTVLSSASCCSAYNILVFSPYPTWSQYIQMEPLFSALGLRGHNVTVVSPFPPKKEQSHFHHIHFVADLYWKIKFSAPTSLKDWMAEIKDKRLPIDFWKELPDASMPEILESSVFQDLIHNENKFDLVFMEVFFGQEPLVVLGHLLDAPVVAFATFGHMPDILRYMGAPNAVAYLSHFNVDYAGSLILTQRLENAWIHYRTTLYDEYWYYPQHDAVLAKYFPGPLPSISDMLRNISLFFLTANTAVDGAKLYPPNVIELPVLHLKDPAPLDKELDVIMNNAQDGVIYFSFGSIVTPSILGEEETQIFLSVLKELNQTVLWKTDWNSTAHDIPKNVYTRDWFDQKSILAHPRCVLFLTHGGLSSLMEAINYAVPVVGMSVFGDQPKNLAYAEYLGYGLHIPHKDLTQNSLRRALRTVLQDGRFKENINRASKIFQDKPMSSLDTAIYWIEYAIRHKGAHHLKPLAVRMPWYQLFLLDIITVCFTIFVVLSYLMFKMISLLLRKYFTRSRPLKEKSN", "md5" : "796910ecf482521a5cabc004b3695770", "matches" : [ { "signature" : { "accession" : "cd03784", "name" : "GT1_Gtf-like", "description" : "GT1_Gtf-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 450, "sites" : [ { "description" : "acceptor substrate-binding pocket", "numLocations" : 1, "siteLocations" : [ { "start" : 32, "end" : 32, "residue" : "Q" } ] }, { "description" : "active site", "numLocations" : 14, "siteLocations" : [ { "start" : 190, "end" : 190, "residue" : "S" }, { "start" : 191, "end" : 191, "residue" : "L" }, { "start" : 195, "end" : 195, "residue" : "Q" }, { "start" : 297, "end" : 297, "residue" : "S" }, { "start" : 34, "end" : 34, "residue" : "I" }, { "start" : 222, "end" : 222, "residue" : "L" }, { "start" : 32, "end" : 32, "residue" : "Q" }, { "start" : 31, "end" : 31, "residue" : "S" }, { "start" : 367, "end" : 367, "residue" : "S" }, { "start" : 187, "end" : 187, "residue" : "Y" }, { "start" : 365, "end" : 365, "residue" : "G" }, { "start" : 371, "end" : 371, "residue" : "E" }, { "start" : 363, "end" : 363, "residue" : "H" }, { "start" : 368, "end" : 368, "residue" : "S" } ] }, { "description" : "TDP-binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 297, "end" : 297, "residue" : "S" }, { "start" : 31, "end" : 31, "residue" : "S" }, { "start" : 367, "end" : 367, "residue" : "S" }, { "start" : 365, "end" : 365, "residue" : "G" }, { "start" : 363, "end" : 363, "residue" : "H" }, { "start" : 368, "end" : 368, "residue" : "S" } ] }, { "description" : "homodimer interface", "numLocations" : 5, "siteLocations" : [ { "start" : 131, "end" : 131, "residue" : "D" }, { "start" : 46, "end" : 46, "residue" : "R" }, { "start" : 19, "end" : 19, "residue" : "Y" }, { "start" : 447, "end" : 447, "residue" : "D" }, { "start" : 448, "end" : 448, "residue" : "T" } ] } ], "evalue" : 4.36662E-61, "score" : 204.322, "location-fragments" : [ { "start" : 19, "end" : 450, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd03784" }, { "signature" : { "accession" : "PS51257", "name" : "PROKAR_LIPOPROTEIN", "description" : "Prokaryotic membrane lipoprotein lipid attachment site profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 15, "score" : 5.0, "alignment" : "MKLL--------------------TFVTVLSSASC", "location-fragments" : [ { "start" : 1, "end" : 15, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51257" }, { "signature" : { "accession" : "PTHR11926", "name" : "GLUCOSYL/GLUCURONOSYL TRANSFERASES", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 282, "end" : 392, "hmmStart" : 52, "hmmEnd" : 126, "hmmLength" : 134, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 120, "envelopeEnd" : 472, "location-fragments" : [ { "start" : 282, "end" : 392, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-14, "familyName" : "GLUCOSYL/GLUCURONOSYL TRANSFERASES", "score" : 55.5, "model-ac" : "PTHR11926" }, { "signature" : { "accession" : "SSF53756", "name" : "UDP-Glycosyltransferase/glycogen phosphorylase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 465, "hmmLength" : 471, "location-fragments" : [ { "start" : 19, "end" : 465, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.08E-87, "model-ac" : "0054711" }, { "signature" : { "accession" : "PF00201", "name" : "UDPGT", "description" : "UDP-glucoronosyl and UDP-glucosyl transferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002213", "name" : "UDP_glucos_trans", "description" : "UDP-glucuronosyl/UDP-glucosyltransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "UDP-glycosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008194" } ], "pathwayXRefs" : [ { "name" : "Glucuronidation", "databaseName" : "Reactome", "id" : "R-HSA-156588" } ] } }, "locations" : [ { "start" : 31, "end" : 509, "hmmStart" : 11, "hmmEnd" : 493, "hmmLength" : 499, "hmmBounds" : "INCOMPLETE", "evalue" : 4.7E-66, "score" : 223.6, "envelopeStart" : 21, "envelopeEnd" : 513, "postProcessed" : true, "location-fragments" : [ { "start" : 31, "end" : 509, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-66, "score" : 224.4, "model-ac" : "PF00201" }, { "signature" : { "accession" : "G3DSA:3.40.50.2000", "name" : "Glycogen Phosphorylase B;", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 270, "end" : 440, "hmmStart" : 6, "hmmEnd" : 169, "hmmLength" : 170, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-45, "score" : 156.4, "envelopeStart" : 270, "envelopeEnd" : 440, "postProcessed" : true, "location-fragments" : [ { "start" : 270, "end" : 440, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-45, "score" : 157.0, "model-ac" : "2o6lB00" } ], "xref" : [ { "name" : "XP_018910401.1 PREDICTED: UDP-glucuronosyltransferase 2C1-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910401.1" } ] },{ "sequence" : "FSPSVFTWSSEVSICGLRHFISIRGNLCHRKESVSPLDDDFSLPERRVLTGHIYPFAVVLRLRVLQIVCGISALVMGTVAFIEERGGFNLGLGVPAGVTTVVAAAASIHTSRGFSGYQQPSCDPPLSRFRFLGPSIQAAIPLTLLWLTACTLNVLLLLFAVRSFIHKPELTVLASVLLTFSLMTLIAVVLLLRIDIKYDPD", "md5" : "ba0554b7576f564757856430465e81b8", "matches" : [ ], "xref" : [ { "name" : "XP_018910151.1 PREDICTED: uncharacterized protein LOC109039213, partial [Bemisia tabaci]", "id" : "XP_018910151.1" } ] },{ "sequence" : "MIFVGYCKNSKGYRLIDPQNPKKVTTSRDVIFLETSLGAAQPEVNGNAHSPDLISPISDEDTSSSENDSQFSSNSKLDDSSSSDSESSASSLSEEVSSEDNYSESSSVSLTSTTLEGQDQEVSERRFPTRIREIPKRLADYVLNLASTSSVCR", "md5" : "e9d3c4b1773e7cda300432940faedb1e", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 56, "end" : 118, "location-fragments" : [ { "start" : 56, "end" : 118, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 38, "end" : 130, "location-fragments" : [ { "start" : 38, "end" : 130, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910022.1 PREDICTED: uncharacterized protein LOC109039124 [Bemisia tabaci]", "id" : "XP_018910022.1" } ] },{ "sequence" : "MTADQIAEKPTLIKWPTQSGAFYTLLMFGPDVPTREKSCEMMWRHWAVGNIPKNDIDKGDTLVEYENIEPFYRAGFHRILFFIYKQPGRRRLNFTSSKGVIKKGSKWEVRGVWYIERFLAKFNLTEPIAANFFFLYDLNPHPEIPHVTVDPLSLIR", "md5" : "49c32bd3dad2e0bee249463a5786ec76", "matches" : [ { "signature" : { "accession" : "PF01161", "name" : "PBP", "description" : "Phosphatidylethanolamine-binding protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR008914", "name" : "PEBP", "description" : "Phosphatidylethanolamine-binding protein", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 108, "hmmStart" : 15, "hmmEnd" : 108, "hmmLength" : 132, "hmmBounds" : "INCOMPLETE", "evalue" : 4.7E-7, "score" : 30.2, "envelopeStart" : 2, "envelopeEnd" : 132, "postProcessed" : true, "location-fragments" : [ { "start" : 13, "end" : 108, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-7, "score" : 30.4, "model-ac" : "PF01161" }, { "signature" : { "accession" : "G3DSA:3.90.280.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 139, "hmmStart" : 45, "hmmEnd" : 173, "hmmLength" : 190, "hmmBounds" : "COMPLETE", "evalue" : 5.5E-34, "score" : 119.4, "envelopeStart" : 1, "envelopeEnd" : 139, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 139, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-34, "score" : 119.6, "model-ac" : "2iqyA00" }, { "signature" : { "accession" : "PTHR11362:SF28", "name" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 134, "hmmStart" : 47, "hmmEnd" : 173, "hmmLength" : 193, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 149, "location-fragments" : [ { "start" : 2, "end" : 134, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-32, "familyName" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "score" : 113.8, "model-ac" : "PTHR11362:SF28" }, { "signature" : { "accession" : "cd00866", "name" : "PEBP_euk", "description" : "PEBP_euk", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR035810", "name" : "PEBP_euk", "description" : "Phosphatidylethanolamine-binding protein, eukaryotic", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 134, "sites" : [ { "description" : "substrate binding site", "numLocations" : 9, "siteLocations" : [ { "start" : 79, "end" : 79, "residue" : "I" }, { "start" : 68, "end" : 68, "residue" : "I" }, { "start" : 70, "end" : 70, "residue" : "P" }, { "start" : 71, "end" : 71, "residue" : "F" }, { "start" : 69, "end" : 69, "residue" : "E" }, { "start" : 45, "end" : 45, "residue" : "H" }, { "start" : 77, "end" : 77, "residue" : "H" }, { "start" : 29, "end" : 29, "residue" : "G" }, { "start" : 43, "end" : 43, "residue" : "W" } ] } ], "evalue" : 1.88129E-30, "score" : 105.918, "location-fragments" : [ { "start" : 1, "end" : 134, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00866" }, { "signature" : { "accession" : "PTHR11362", "name" : "PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR035810", "name" : "PEBP_euk", "description" : "Phosphatidylethanolamine-binding protein, eukaryotic", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 134, "hmmStart" : 47, "hmmEnd" : 173, "hmmLength" : 193, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 149, "location-fragments" : [ { "start" : 2, "end" : 134, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-32, "familyName" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "score" : 113.8, "model-ac" : "PTHR11362" }, { "signature" : { "accession" : "SSF49777", "name" : "PEBP-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 134, "hmmLength" : 184, "location-fragments" : [ { "start" : 2, "end" : 134, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.46E-28, "model-ac" : "0035501" } ], "xref" : [ { "name" : "XP_018910114.1 PREDICTED: phosphatidylethanolamine-binding protein homolog F40A3.3-like isoform X4 [Bemisia tabaci]", "id" : "XP_018910114.1" } ] },{ "sequence" : "MSVRVSGVYLYPQSPNSLSPNSEKNNLNSINSGNGSPAPTMKPPAVAIVTPQRSNSLDYLNFEEKRRIIASSLSLTDFLHHHHHTDGSATTPASPNSLAKKQNGAALRTNSLGSGTRTPPLPLERKPVSKFSALGRLFKPWKWKRRKKSDKFEAASRSLERKISVRANRDELVQKGILILESPTSPIPESHCETPLSGALPTISTSLSAGNGNHLSNNATDLKKDKTESMPAVNGSCIVSEQPPPPAPSLDMHSMQNMSMGRMESMNMQNMQQMSMTMAGTPRPERPERPSSLGGAVPPSQGGPGASLARRLRSYHNDHYSPTSNRPLQPPSLLQTVVDGGTPNRQGCSTPPPPPVAPSLVLSELPEPPIPVSEIGPIPPPPMFSSPSPIPRNTHTNRSDQHPDYGYSNAFKSIRRREEDYSDGEEGDVRCDYDSDIDDDDCFSPQPDPSIDTNRVEEILAKEPKFHAMPLKSALKKPPTPTQDLPSHTAANTRPVRLGLTLPCTMENKENSRPFSDSDSSSDGDGPILYRDDEEGGLATKIARKDSLALKLALRPDRQELIDRNILQIQSEKERQESKEAVGARLIRRLSMRPTQEELEERNILKKQSAAEERKLKEEKKRVLLRKLSFRPTVEELKEKKIIRFNDYIEVTQAHDYDRRADKPWTRLTPKDKAAIRKELNEFKSTEMEVHQESRHLTRFHRP", "md5" : "39729c9b9d28ce59571a3e1242772979", "matches" : [ { "signature" : { "accession" : "PF02755", "name" : "RPEL", "description" : "RPEL repeat", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004018", "name" : "RPEL_repeat", "description" : "RPEL repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 624, "end" : 646, "hmmStart" : 2, "hmmEnd" : 24, "hmmLength" : 24, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.3E-6, "score" : 27.9, "envelopeStart" : 623, "envelopeEnd" : 646, "postProcessed" : true, "location-fragments" : [ { "start" : 624, "end" : 646, "dc-status" : "CONTINUOUS" } ] }, { "start" : 586, "end" : 607, "hmmStart" : 2, "hmmEnd" : 23, "hmmLength" : 24, "hmmBounds" : "INCOMPLETE", "evalue" : 4.9E-7, "score" : 29.2, "envelopeStart" : 585, "envelopeEnd" : 608, "postProcessed" : true, "location-fragments" : [ { "start" : 586, "end" : 607, "dc-status" : "CONTINUOUS" } ] }, { "start" : 158, "end" : 178, "hmmStart" : 1, "hmmEnd" : 21, "hmmLength" : 24, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.7E-7, "score" : 29.0, "envelopeStart" : 158, "envelopeEnd" : 179, "postProcessed" : true, "location-fragments" : [ { "start" : 158, "end" : 178, "dc-status" : "CONTINUOUS" } ] }, { "start" : 547, "end" : 568, "hmmStart" : 1, "hmmEnd" : 22, "hmmLength" : 24, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.5E-7, "score" : 29.7, "envelopeStart" : 547, "envelopeEnd" : 570, "postProcessed" : true, "location-fragments" : [ { "start" : 547, "end" : 568, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-31, "score" : 105.0, "model-ac" : "PF02755" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 389, "end" : 406, "location-fragments" : [ { "start" : 389, "end" : 406, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51073", "name" : "RPEL", "description" : "RPEL repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR004018", "name" : "RPEL_repeat", "description" : "RPEL repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 622, "end" : 647, "score" : 9.153, "alignment" : "RVLLRKLSFRPTVEELKEKKIIRFND", "location-fragments" : [ { "start" : 622, "end" : 647, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51073" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 45, "location-fragments" : [ { "start" : 14, "end" : 45, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 347, "end" : 388, "location-fragments" : [ { "start" : 347, "end" : 388, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 274, "end" : 434, "location-fragments" : [ { "start" : 274, "end" : 434, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 84, "end" : 124, "location-fragments" : [ { "start" : 84, "end" : 124, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 318, "end" : 346, "location-fragments" : [ { "start" : 318, "end" : 346, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 38, "location-fragments" : [ { "start" : 14, "end" : 38, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 505, "end" : 523, "location-fragments" : [ { "start" : 505, "end" : 523, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51073", "name" : "RPEL", "description" : "RPEL repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR004018", "name" : "RPEL_repeat", "description" : "RPEL repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 157, "end" : 182, "score" : 9.892, "alignment" : "RSLERKISVRANRDELVQKGILILES", "location-fragments" : [ { "start" : 157, "end" : 182, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51073" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 602, "end" : 622, "location-fragments" : [ { "start" : 602, "end" : 622, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR12751", "name" : "PHOSPHATASE AND ACTIN REGULATOR PHACTR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 88, "end" : 703, "hmmStart" : 7, "hmmEnd" : 688, "hmmLength" : 688, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 41, "envelopeEnd" : 703, "location-fragments" : [ { "start" : 88, "end" : 703, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-134, "familyName" : "PHOSPHATASE AND ACTIN REGULATOR PHACTR", "score" : 451.9, "model-ac" : "PTHR12751" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 88, "end" : 117, "location-fragments" : [ { "start" : 88, "end" : 117, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51073", "name" : "RPEL", "description" : "RPEL repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR004018", "name" : "RPEL_repeat", "description" : "RPEL repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 584, "end" : 609, "score" : 9.724, "alignment" : "ARLIRRLSMRPTQEELEERNILKKQS", "location-fragments" : [ { "start" : 584, "end" : 609, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51073" }, { "signature" : { "accession" : "PS51073", "name" : "RPEL", "description" : "RPEL repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR004018", "name" : "RPEL_repeat", "description" : "RPEL repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 546, "end" : 571, "score" : 11.238, "alignment" : "DSLALKLALRPDRQELIDRNILQIQS", "location-fragments" : [ { "start" : 546, "end" : 571, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51073" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 475, "end" : 532, "location-fragments" : [ { "start" : 475, "end" : 532, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00707", "name" : "rpel", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR004018", "name" : "RPEL_repeat", "description" : "RPEL repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 546, "end" : 571, "hmmStart" : 1, "hmmEnd" : 26, "hmmLength" : 26, "hmmBounds" : "COMPLETE", "evalue" : 8.7E-7, "score" : 38.6, "location-fragments" : [ { "start" : 546, "end" : 571, "dc-status" : "CONTINUOUS" } ] }, { "start" : 622, "end" : 647, "hmmStart" : 1, "hmmEnd" : 26, "hmmLength" : 26, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-8, "score" : 44.9, "location-fragments" : [ { "start" : 622, "end" : 647, "dc-status" : "CONTINUOUS" } ] }, { "start" : 157, "end" : 182, "hmmStart" : 1, "hmmEnd" : 26, "hmmLength" : 26, "hmmBounds" : "COMPLETE", "evalue" : 0.0067, "score" : 25.6, "location-fragments" : [ { "start" : 157, "end" : 182, "dc-status" : "CONTINUOUS" } ] }, { "start" : 584, "end" : 609, "hmmStart" : 1, "hmmEnd" : 26, "hmmLength" : 26, "hmmBounds" : "COMPLETE", "evalue" : 8.0E-8, "score" : 42.0, "location-fragments" : [ { "start" : 584, "end" : 609, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-40, "score" : 151.1, "model-ac" : "SM00707" } ], "xref" : [ { "name" : "XP_018909757.1 PREDICTED: phosphatase and actin regulator 4B isoform X2 [Bemisia tabaci]", "id" : "XP_018909757.1" } ] },{ "sequence" : "MYFKTFSFYLMSIVLGGFAAPLLDGLLGSNGLTSDPSNLAHQVTGNSPVDVSAALNNAQGLTTRALPGLDILNGVTSNVPQGVTGNVPVDVSDALNIVQGLATRALGLDILKSDPTNVAQEVVGNSPVDVSGALNIAQGLATRALPGLDILNGASSNLPQEVVGNSPVDVSGALNIAQGLATRALPGLDILNGASSNLPQEVMNNAPADPSNVLNMVQGLATRALPGLNILNGDLTNLPQEALANVPTDILPNGTVDVQGLLTRGLNNGNQARKPNKQGGQPQSFGPLGGNLQSFNGLLRNGQGSGTRV", "md5" : "ac4bac8f6bb570c2cd32c3045ed928be", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 266, "end" : 309, "location-fragments" : [ { "start" : 266, "end" : 309, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909711.1 PREDICTED: uncharacterized protein LOC109038902 isoform X1 [Bemisia tabaci]", "id" : "XP_018909711.1" } ] },{ "sequence" : "MLALIYGLYYIQLGPISSAVYVALSHTSWALALSWIIIMCMIGRAGFIDKVLSFKYLYPLSRITYCAYLIHPQLMRSAVLTSDATTHISVQMASVIFLGFVLLSYSLAFAMSLMFEAPFVSLLKVAHPTRRKTR", "md5" : "4d4edd3595fe415ea1df8faa604ca7ef", "matches" : [ { "signature" : { "accession" : "PTHR11161:SF0", "name" : "O-ACYLTRANSFERASE LIKE PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 132, "hmmStart" : 409, "hmmEnd" : 543, "hmmLength" : 554, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 134, "location-fragments" : [ { "start" : 2, "end" : 132, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-35, "familyName" : "O-ACYLTRANSFERASE LIKE PROTEIN", "score" : 125.0, "model-ac" : "PTHR11161:SF0" }, { "signature" : { "accession" : "PTHR11161", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 132, "hmmStart" : 409, "hmmEnd" : 543, "hmmLength" : 554, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 134, "location-fragments" : [ { "start" : 2, "end" : 132, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-35, "familyName" : "O-ACYLTRANSFERASE LIKE PROTEIN", "score" : 125.0, "model-ac" : "PTHR11161" } ], "xref" : [ { "name" : "XP_018910280.1 PREDICTED: nose resistant to fluoxetine protein 6-like [Bemisia tabaci]", "id" : "XP_018910280.1" } ] },{ "sequence" : "MYPGMDRNFRRSPARLANIAARKQSPARPKSPAKSKSPARSKSPSKPKSPAKSKSPSRSRPKSPARGKSPAKKSPARKASKSPARKPKSPTKAKSEPKPSPAKKPSKKKVFPEDDYSDSETSSVSVEPMKLDPKVEAVAAEVSQLPYRRSVRQVIKQIAASGEGKLDDGIKDEVKEILKANNVRTSSKSSSPKGYEVLFKALLYLIVFPAIVTLTHLSCTRAESCKLWPVRFPQTWRYFVNLESSLIFLGFVVWQIFLSILPVGKKVSGISESLEYRLSGLLSAFLTLSAIGGLRYFKFPVLSVLDRPMPLITTSYAVALLVSIVLFVKGGKAAKKSLNPKGNTGNKINDFIVGRELNPRIKSFDFKLFFKRHALLTALVYNALVALKLYETHKTLNTLPVTAVTIIALQTLFILDSLFFEDNFVTTFEAQVEGVGFRSVVYYTLYPFVFINLVKYLLISKVEKSPYVLGAIVVAQLIGYLIYRASNYQKNEFRKNPLNPRASALETIPTVQGRKLIVSGLWGKLQHPNYLGQLIIEWSWAFAADFKLWVPFVSAILLTITLIYRAVVVNAHNKSVYGTSWDRYTSRVKYSLIPKVF", "md5" : "de5e7db0dad42e36f370889629e994be", "matches" : [ { "signature" : { "accession" : "PTHR21257", "name" : "STEROL REDUCTASE/LAMIN B RECEPTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 184, "end" : 597, "hmmStart" : 41, "hmmEnd" : 467, "hmmLength" : 467, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 15, "envelopeEnd" : 597, "location-fragments" : [ { "start" : 184, "end" : 597, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-94, "familyName" : "DELTA(14)-STEROL REDUCTASE", "score" : 319.6, "model-ac" : "PTHR21257" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 36, "end" : 52, "location-fragments" : [ { "start" : 36, "end" : 52, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF01222", "name" : "ERG4_ERG24", "description" : "Ergosterol biosynthesis ERG4/ERG24 family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001171", "name" : "Ergosterol_biosynth_ERG4_ERG24", "description" : "Ergosterol biosynthesis ERG4/ERG24", "type" : "FAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "sterol biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0016126" }, { "name" : "oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016628" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 240, "end" : 597, "hmmStart" : 66, "hmmEnd" : 432, "hmmLength" : 432, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.1E-66, "score" : 223.5, "envelopeStart" : 195, "envelopeEnd" : 597, "postProcessed" : true, "location-fragments" : [ { "start" : 240, "end" : 597, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-66, "score" : 223.8, "model-ac" : "PF01222" }, { "signature" : { "accession" : "G3DSA:1.20.120.1630", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 401, "end" : 597, "hmmStart" : 45, "hmmEnd" : 193, "hmmLength" : 194, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-5, "score" : 26.1, "envelopeStart" : 401, "envelopeEnd" : 597, "postProcessed" : true, "location-fragments" : [ { "start" : 401, "end" : 597, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-5, "score" : 26.1, "model-ac" : "4a2nB00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 89, "end" : 116, "location-fragments" : [ { "start" : 89, "end" : 116, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR21257:SF17", "name" : "DELTA(14)-STEROL REDUCTASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 184, "end" : 597, "hmmStart" : 41, "hmmEnd" : 467, "hmmLength" : 467, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 15, "envelopeEnd" : 597, "location-fragments" : [ { "start" : 184, "end" : 597, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-94, "familyName" : "DELTA(14)-STEROL REDUCTASE", "score" : 319.6, "model-ac" : "PTHR21257:SF17" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 53, "end" : 88, "location-fragments" : [ { "start" : 53, "end" : 88, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 128, "location-fragments" : [ { "start" : 1, "end" : 128, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910356.1 PREDICTED: delta(14)-sterol reductase-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910356.1" } ] },{ "sequence" : "MAIFEQKHLKKEIIDDTHSLSCTIINAQLTQGHIDYTLRVLRSKFEDKVWHVTKRYSDFDSLYNALQISGLKFQFPPKKYFGNLNPEFVAERQVGLQSFLDTVLMNPILSLSLPVRRFLNPETYSIPFQEQAMTKVSMILRGERDYEIVKPLDDIGWRIRKQYVHIRNRNSSISKQDFILAWIEFGPDKYLTDKELQSSLKCLMDLQHPFIEPTLLAVCNESGGLVIRRYNPPGSLRDILYGSSPNQPFLKKYCNPKERKPLPPNTVANYATQILHALKFLRDKKLPFGHLHTSNILVENNRVKLTDIENSLFGVSNYYRPYISQLRKVNTMEAVDVYCFAHTLYEMSTGSPLQQSTCDELPANCPSMFRPVLELILSSEACRKTGLPTLDYLLDHPLFSHNSFIPVTEPKPHFKVSSHLKEAFRKLSLQIEKRLGEEQKKIRYQKKLYLMQEQLIVEENNRQKEKKKQRSKKHSESIANGKSERCSSPNSVATSAGTVTPPSGASSSHFTPPSASDLASSLSTPPPPPPPPFQSNGNSRSELLNSICNFKKSELKKTKPT", "md5" : "d68bf5cfb176ac076b08ec9ded772732", "matches" : [ { "signature" : { "accession" : "SSF64268", "name" : "PX domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036871", "name" : "PX_dom_sf", "description" : "PX domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "phosphatidylinositol binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0035091" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 18, "end" : 123, "hmmLength" : 132, "location-fragments" : [ { "start" : 18, "end" : 123, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.44E-22, "model-ac" : "0041789" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 481, "end" : 521, "location-fragments" : [ { "start" : 481, "end" : 521, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00787", "name" : "PX", "description" : "PX domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001683", "name" : "Phox", "description" : "Phox homologous domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "phosphatidylinositol binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0035091" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 121, "hmmStart" : 3, "hmmEnd" : 83, "hmmLength" : 84, "hmmBounds" : "INCOMPLETE", "evalue" : 3.8E-13, "score" : 49.9, "envelopeStart" : 42, "envelopeEnd" : 122, "postProcessed" : true, "location-fragments" : [ { "start" : 44, "end" : 121, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.6E-14, "score" : 51.8, "model-ac" : "PF00787" }, { "signature" : { "accession" : "PF07714", "name" : "PK_Tyr_Ser-Thr", "description" : "Protein tyrosine and serine/threonine kinase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001245", "name" : "Ser-Thr/Tyr_kinase_cat_dom", "description" : "Serine-threonine/tyrosine-protein kinase, catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 193, "end" : 309, "hmmStart" : 45, "hmmEnd" : 148, "hmmLength" : 259, "hmmBounds" : "INCOMPLETE", "evalue" : 1.2E-8, "score" : 34.5, "envelopeStart" : 187, "envelopeEnd" : 370, "postProcessed" : true, "location-fragments" : [ { "start" : 193, "end" : 309, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-10, "score" : 39.4, "model-ac" : "PF07714" }, { "signature" : { "accession" : "G3DSA:3.30.1520.10", "name" : "PX domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036871", "name" : "PX_dom_sf", "description" : "PX domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "phosphatidylinositol binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0035091" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 141, "hmmStart" : 11, "hmmEnd" : 125, "hmmLength" : 154, "hmmBounds" : "COMPLETE", "evalue" : 7.2E-23, "score" : 82.9, "envelopeStart" : 14, "envelopeEnd" : 141, "postProcessed" : true, "location-fragments" : [ { "start" : 14, "end" : 141, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-23, "score" : 83.4, "model-ac" : "4ikdA00" }, { "signature" : { "accession" : "PS51082", "name" : "WH2", "description" : "WH2 domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR003124", "name" : "WH2_dom", "description" : "WH2 domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "actin binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003779" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 539, "end" : 558, "score" : 8.089, "alignment" : "SRSELLNSICNfKK-SELKKT", "location-fragments" : [ { "start" : 539, "end" : 558, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51082" }, { "signature" : { "accession" : "PTHR22999", "name" : "PX SERINE/THREONINE KINASE PXK", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 13, "end" : 559, "hmmStart" : 4, "hmmEnd" : 552, "hmmLength" : 562, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 561, "location-fragments" : [ { "start" : 13, "end" : 559, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-164, "familyName" : "PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN", "score" : 550.7, "model-ac" : "PTHR22999" }, { "signature" : { "accession" : "G3DSA:1.10.510.10", "name" : "Transferase(Phosphotransferase) domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 192, "end" : 405, "hmmStart" : 5, "hmmEnd" : 222, "hmmLength" : 230, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-16, "score" : 62.6, "envelopeStart" : 192, "envelopeEnd" : 405, "postProcessed" : true, "location-fragments" : [ { "start" : 192, "end" : 405, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-17, "score" : 63.6, "model-ac" : "2y4pD00" }, { "signature" : { "accession" : "PTHR22999:SF18", "name" : "PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 13, "end" : 559, "hmmStart" : 4, "hmmEnd" : 552, "hmmLength" : 562, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 561, "location-fragments" : [ { "start" : 13, "end" : 559, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-164, "familyName" : "PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN", "score" : 550.7, "model-ac" : "PTHR22999:SF18" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 190, "end" : 401, "hmmLength" : 293, "location-fragments" : [ { "start" : 190, "end" : 401, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.28E-22, "model-ac" : "0046210" }, { "signature" : { "accession" : "PS50195", "name" : "PX", "description" : "PX domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001683", "name" : "Phox", "description" : "Phox homologous domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "phosphatidylinositol binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0035091" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 126, "score" : 14.263, "alignment" : "IDDTHSLSCTIINAQLTQGHIDYTLRVLRSKFeDKVWHVTKRYSDFDSLYNALQIS---GLKFQFPPKKYFGN-LNPEFVAERQVGLQSFLDTVLMNPILSLSLPVRRFLNPETYSI", "location-fragments" : [ { "start" : 14, "end" : 126, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50195" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 461, "end" : 561, "location-fragments" : [ { "start" : 461, "end" : 561, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50011", "name" : "PROTEIN_KINASE_DOM", "description" : "Protein kinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 149, "end" : 399, "score" : 10.28, "alignment" : "VKPLDDIGWRIRKQYVHIRNRNssiSKQDFILAWIEF---GPDkylTDKELQSSLKCLMDLQHPFIEPTLLAVCNESGGLVIRRYNPPGSLRDILYGSSPNqpflkkycnpkerkpLPPNTVANYATQILHALKFLRDKKLPFGHLHTSNILVEN-NRVKLTD------------IENSLFGVSNYYRPYISQLRKVNTMeAVDVYCFAHTLYEMSTGS-PLQ--QSTCDELPANCPS-----------MFRPVLELILSSEACRKTGLPTLDYLLDHPLF", "location-fragments" : [ { "start" : 149, "end" : 399, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50011" }, { "signature" : { "accession" : "cd00180", "name" : "PKc", "description" : "PKc", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 194, "end" : 348, "sites" : [ ], "evalue" : 1.32527E-13, "score" : 68.0659, "location-fragments" : [ { "start" : 194, "end" : 348, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00180" }, { "signature" : { "accession" : "SM00312", "name" : "PX_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001683", "name" : "Phox", "description" : "Phox homologous domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "phosphatidylinositol binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0035091" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 17, "end" : 122, "hmmStart" : 1, "hmmEnd" : 142, "hmmLength" : 142, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-8, "score" : 44.7, "location-fragments" : [ { "start" : 17, "end" : 122, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-8, "score" : 44.7, "model-ac" : "SM00312" } ], "xref" : [ { "name" : "XP_018910413.1 PREDICTED: PX domain-containing protein kinase-like protein [Bemisia tabaci]", "id" : "XP_018910413.1" } ] },{ "sequence" : "IPELAGFWMLSFLLQLPLQLFLLANEGVRPTGVERAVQGVEVALLLAQLGTGFVALRTTAAHQAHKFHLAQFLAPGPGAFKEAAGSTPDAPRDEDPFHDVRRNPRGTENPFEDMQRNLLVSDQLFRDAERIPLASISRGSSTKTD", "md5" : "a1f73f70a2745f9e98cbe539645a6b77", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 78, "end" : 115, "location-fragments" : [ { "start" : 78, "end" : 115, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR13531:SF14", "name" : "TRANSMEMBRANE PROTEIN 17", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 72, "hmmStart" : 108, "hmmEnd" : 179, "hmmLength" : 224, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 116, "location-fragments" : [ { "start" : 1, "end" : 72, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-21, "familyName" : "TRANSMEMBRANE PROTEIN 17", "score" : 79.1, "model-ac" : "PTHR13531:SF14" }, { "signature" : { "accession" : "PTHR13531", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR019184", "name" : "Uncharacterised_TM-17", "description" : "Uncharacterised protein family, transmembrane-17", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 72, "hmmStart" : 108, "hmmEnd" : 179, "hmmLength" : 224, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 116, "location-fragments" : [ { "start" : 1, "end" : 72, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-21, "familyName" : "TRANSMEMBRANE PROTEIN 17", "score" : 79.1, "model-ac" : "PTHR13531" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 87, "end" : 109, "location-fragments" : [ { "start" : 87, "end" : 109, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910279.1 PREDICTED: uncharacterized protein LOC109039310, partial [Bemisia tabaci]", "id" : "XP_018910279.1" } ] },{ "sequence" : "MSSYRSNYSSYSSSYLGSRFNTVTRTYTSSGSSRSSFSSGFTPTSSSVLSLRDKYNSLSRNSTSSVGTSRTERSSSQYDSKSGSDSYSRSYSTYKPYSSTSTESSTRASSYTPYKSYTAGSSDSSSKSTYTPWSKSYRSSVPESTYSYRSRYSSKPDAEASTEKSSTYRSSYSKPEPESNSYTSSSRDVDSRSSYSRFKSDPEPTPRKDEPEVSSYSKPSSEYKPSSYSSKNETDTSSAKDSLSVYSRYGHYGTRKSPAPSASEESKDEVKVSVTTRYTSPTPPSNSAYLRNRRAELESIYQCEIVRKSRVSKTDCQTQTDENDIYAAMKSESSEGENSEPAEPPLAASRSPVHISKSDVDVNQNIKESESFNYVRPTDITSKTVITVDSSLDPARGVHPSTEESLFAPSTFQYTSSYPNLKNSSTVSSHPNSLSVSTAILNLPNKSPTFSESDVSEKQSSPDGSLSAGKASFEKFPSPEKISEDSKNSAASKEGYKSSSSPSFGLEKAVPNQKCSLKSSSPARSPSPNSRLSRSRSPTPSYSFTISPRHHQTRSKDSSASQTNEFSVAQPEILDKSSSYHLNIPSAFQLNLEKKMSDPSRSLSRSPSPSPARGRTPENINYSSLNDPNQPSAGRLLSLAKSTSFVSKKAEYIEPVVSVPFKSTHRFSEQFSDSDISRSETSVPKIRLATYPSDSEEPYRKDTKGCSSERVPEKPIKTSESDSLSFNGPPSSTSQSPFPQEECASKPPVHPASPIVGIRVSSKERMESLRYAMMRSETPAMAFKNKSFESSSEDISDLTFDFSGKHYVINEFTENHIPNARKPLESINNEKPKEGDSFSQTEGMGQAQSQKIRKFDSGERDWWARDDTQSESFRHSSRHDSTEPPNDSSKEFSYHGAQSESMSPDGTKYPSQHHIRKFDSGERDWWAQNEPGRDAPSESPQNDIQHDSSNDSSGEFSNHEAQSRSVSPDYPKQSSQHHIRKFDSGEREWWLEDERNSGSVEGALDEDEAVENEEEEVDFWAELAAENEKHELELQHAYQLRNMDVDSSSWWIEEKTKDGDRDNQPSSGISRRTPEEDEANADEYYDAEADNSAHERNEEIYSYSIRKFDSGETPWFAEQENDDQTDKRPGSDSCQDQNQVESGIWSMETFDSTSNRPSEQFLIRTGSGHTLWYAADKSEPPVELANNERFFKIGEGERMCWIDDNTLSHTYSGSATEQPWFPDKTLSEDQVEGPYKIKRIESGEKPWWLDEDEKTDAGFDDTLCSHFRGSESRSENNVTRADLSSKASDGEEDLEPFSRVVRRVPNPTLFISELTNIDQLLGDELSFSNQCLEPTFAKIKDDGPASEDEDEIEEVSADQVKIHDNTPQTYIIEPFKGILKLDDAALQLYKDGDYSSYLDLDATISEQQEEFEGFQSNRKNSIVLRTQLSVRVHTIIEKLLNSEGSELRRALFCLKQIFQEDKDLVHEFVQNDGLSCLIKVGSDANQNYQNYILRALGQVMLYVDGMNGVIEHNETIQWLYCLVSSKFRLVVKTALKLLLVFVEYVESNCLLLIQAIHTVDKSRGSLPWSNIMKLLNEYDVTDTELLIYAMTLINKTLNRVPDLDMYYDQVDEIEKQGIQEIVQRYMSRPGTDLDFLHQLQSYEAVLNHEDGGDKTIPLKQLDDNVRTTRFSNASMISDIERRRSRRHSTGTVPLSLSVSPYNKANEDYHLKQAEDGVGVTPALRRRLERGDRQKLLIPQEELCKSSTENYSSDDGGMKNGLKSELSNGDLKYYNGETESCLPRENTVKDLTQRLATLNSPNEESPTKLTPPPRVGEMKGIISKAIEGLAKSQSKSELKSPTNETPPMRIPEVKKSETELHWEELLASTTRALQLCDLDFTDLGSDDEKNILAPTSVANGIPPPPPPCVLPPPAPAAPLQSLTKTKKTVKLFWKEVCEDPIVMAKMNSSLIWDELTPVPVDTQKLEHLFESRTKDLITKEKQHELNKNKEIIVLDPKRSNAINIGMTKLPPPRAIKTAILKMDATVMNREGIEKLLTMLPSEEERTKIQEAQTANPELPLGSAEQFLLTLASIIELPARLKLWAFKLDYENSEKEIAEPLMDLKQGMELLKANKTFRAILATLLSIGIFLNGNEVKGFQIEYLAKVPEVKDTVHKHSLLHHLCHMVMSKFPQSTDLYSEIGAVTRASKVDFDELALSIHRMEQECKASFDHLKVIVKHDGSNAMKGKMSDFLADCAERIIVLCKVHRRVINRYHKFCLWLGIPLHRVCLTKPNELCRIISEFALEYRTTRERVLQQLEKKANHRERNKTRGKMITEIGKVDTKEDRADAELRQLLGNESIDRPNSASPLHGSLPWRRQKKNSNGKGSPDQRKNGHLTDGDDELLETLVKTATKIPATRSAPRERKRIRNADRKSFRQRTLRNGLSEEDKKYLASYIESF", "md5" : "214f875f0cbf2f99d9b9d39574b483f0", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 144, "end" : 294, "location-fragments" : [ { "start" : 144, "end" : 294, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51232", "name" : "GBD_FH3", "description" : "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR014768", "name" : "GBD/FH3_dom", "description" : "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1373, "end" : 1729, "score" : 20.381, "alignment" : "EPFKGILKLDDAALQLYKDGDYSS---YLDLDATISEQQEEFEGFQSNR--------KNSIVLRTQLSVRVHTIIEKLLNSEGSELRRALFCLKqifqedKDLVHEFVQNDGLSCLIKVGSDANQN---------YQNYILRALGQVMLYVDGMNGVIEHNETIQWLYCLVSSKFRLVVKTALKLLLVFVEY-VESNCLLLIQAIHTVDKS-RGSLPWSNIMKLLNEYDVTDTELLIYAMTLINKTLNRVPDLDMYYDQVDEIEKQGIQEIVQRYMSrPGTDLDFLHQLQSYeAVLNHEDGGDKTIPLKQLDD-NVRTTRFSNASMISDIERRRSRRHSTGTVPLSLSVSPYNKANEDYHLKQAEDGVGVTPALRRRLER", "location-fragments" : [ { "start" : 1373, "end" : 1729, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51232" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 439, "end" : 467, "location-fragments" : [ { "start" : 439, "end" : 467, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 974, "end" : 1002, "location-fragments" : [ { "start" : 974, "end" : 1002, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF18382", "name" : "Formin_GBD_N", "description" : "Formin N-terminal GTPase-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR041387", "name" : "FHOD1_GBD_N", "description" : "FHOD1, N-terminal GTPase-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1378, "end" : 1427, "hmmStart" : 50, "hmmEnd" : 99, "hmmLength" : 99, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.3E-16, "score" : 59.0, "envelopeStart" : 1360, "envelopeEnd" : 1427, "postProcessed" : true, "location-fragments" : [ { "start" : 1378, "end" : 1427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-16, "score" : 60.8, "model-ac" : "PF18382" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 887, "end" : 908, "location-fragments" : [ { "start" : 887, "end" : 908, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2397, "end" : 2412, "location-fragments" : [ { "start" : 2397, "end" : 2412, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 588, "end" : 635, "location-fragments" : [ { "start" : 588, "end" : 635, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 492, "end" : 549, "location-fragments" : [ { "start" : 492, "end" : 549, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 273, "end" : 289, "location-fragments" : [ { "start" : 273, "end" : 289, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1048, "end" : 1078, "location-fragments" : [ { "start" : 1048, "end" : 1078, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 593, "end" : 635, "location-fragments" : [ { "start" : 593, "end" : 635, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF101447", "name" : "Formin homology 2 domain (FH2 domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 1901, "end" : 2305, "hmmLength" : 411, "location-fragments" : [ { "start" : 1901, "end" : 2305, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.96E-84, "model-ac" : "0044554" }, { "signature" : { "accession" : "SM00498", "name" : "it6_source", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR015425", "name" : "FH2_Formin", "description" : "Formin, FH2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1917, "end" : 2364, "hmmStart" : 1, "hmmEnd" : 499, "hmmLength" : 499, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-58, "score" : 209.8, "location-fragments" : [ { "start" : 1917, "end" : 2364, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-58, "score" : 209.8, "model-ac" : "SM00498" }, { "signature" : { "accession" : "PS51444", "name" : "FH2", "description" : "Formin homology-2 (FH2) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR015425", "name" : "FH2_Formin", "description" : "Formin, FH2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1917, "end" : 2311, "score" : 43.936, "alignment" : "PLQSLTKTKKTVKLFWKEVcEDPIVMAKMNSSLIWdELTPVPVDTQKLEHLFESR---TKDLITKEKQHELNKNKEIIVLDPKRSNAINIGMTKL-PPPRAIKTAILKMDATVMNREGIEKLLTMLPSEEERTKIQEAQTANPeLPLGSAEQFLLTLASIIELPARLKLWAFKLDYENSEKEIAEPLMDLKQGMELLKANKTFRAILATLLSIGIFLNGN----EVKGFQIEYLAKVPEVKDTVHKHSLLHHLCHMVMSKFPQSTDLYSEIGAVTRASKVDFDELALSIHRMEQECKASFDHLKVIVKH--DGSNAMKGKMSDFLADCAERIIVLCKVHRRVINRYHKFCLWLGIPLHrvcLTKPNELCRIISEFALEYRTTRERVLQQLEKKANHRERNKTRGK", "location-fragments" : [ { "start" : 1917, "end" : 2311, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51444" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 192, "end" : 215, "location-fragments" : [ { "start" : 192, "end" : 215, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 934, "end" : 973, "location-fragments" : [ { "start" : 934, "end" : 973, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 216, "end" : 244, "location-fragments" : [ { "start" : 216, "end" : 244, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 910, "end" : 929, "location-fragments" : [ { "start" : 910, "end" : 929, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 318, "end" : 335, "location-fragments" : [ { "start" : 318, "end" : 335, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 813, "end" : 1015, "location-fragments" : [ { "start" : 813, "end" : 1015, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 694, "end" : 717, "location-fragments" : [ { "start" : 694, "end" : 717, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 144, "end" : 191, "location-fragments" : [ { "start" : 144, "end" : 191, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 477, "end" : 491, "location-fragments" : [ { "start" : 477, "end" : 491, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 718, "end" : 741, "location-fragments" : [ { "start" : 718, "end" : 741, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2361, "end" : 2386, "location-fragments" : [ { "start" : 2361, "end" : 2386, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 674, "end" : 688, "location-fragments" : [ { "start" : 674, "end" : 688, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF48371", "name" : "ARM repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016024", "name" : "ARM-type_fold", "description" : "Armadillo-type fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1436, "end" : 1651, "hmmLength" : 343, "location-fragments" : [ { "start" : 1436, "end" : 1651, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.38E-27, "model-ac" : "0052018" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 52, "end" : 109, "location-fragments" : [ { "start" : 52, "end" : 109, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1087, "end" : 1105, "location-fragments" : [ { "start" : 1087, "end" : 1105, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 314, "end" : 359, "location-fragments" : [ { "start" : 314, "end" : 359, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2297, "end" : 2412, "location-fragments" : [ { "start" : 2297, "end" : 2412, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF02181", "name" : "FH2", "description" : "Formin Homology 2 Domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR015425", "name" : "FH2_Formin", "description" : "Formin, FH2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1920, "end" : 2285, "hmmStart" : 4, "hmmEnd" : 371, "hmmLength" : 372, "hmmBounds" : "INCOMPLETE", "evalue" : 6.4E-83, "score" : 278.9, "envelopeStart" : 1917, "envelopeEnd" : 2286, "postProcessed" : true, "location-fragments" : [ { "start" : 1920, "end" : 2285, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.4E-83, "score" : 278.9, "model-ac" : "PF02181" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 439, "end" : 574, "location-fragments" : [ { "start" : 439, "end" : 574, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2297, "end" : 2331, "location-fragments" : [ { "start" : 2297, "end" : 2331, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 2435, "end" : 2438, "location-fragments" : [ { "start" : 2435, "end" : 2438, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 557, "end" : 574, "location-fragments" : [ { "start" : 557, "end" : 574, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 853, "end" : 886, "location-fragments" : [ { "start" : 853, "end" : 886, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.20.58.2220", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042201", "name" : "FH2_Formin_sf", "description" : "Formin, FH2 domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1983, "end" : 2315, "hmmStart" : 4, "hmmEnd" : 327, "hmmLength" : 340, "hmmBounds" : "COMPLETE", "evalue" : 5.4E-80, "score" : 270.9, "envelopeStart" : 1983, "envelopeEnd" : 2315, "postProcessed" : true, "location-fragments" : [ { "start" : 1983, "end" : 2315, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-80, "score" : 271.6, "model-ac" : "1v9dB00" }, { "signature" : { "accession" : "G3DSA:1.25.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011989", "name" : "ARM-like", "description" : "Armadillo-like helical", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1351, "end" : 1651, "hmmStart" : 62, "hmmEnd" : 339, "hmmLength" : 339, "hmmBounds" : "COMPLETE", "evalue" : 8.7E-132, "score" : 440.9, "envelopeStart" : 1351, "envelopeEnd" : 1651, "postProcessed" : true, "location-fragments" : [ { "start" : 1351, "end" : 1651, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.7E-132, "score" : 440.9, "model-ac" : "3dadA00" }, { "signature" : { "accession" : "PTHR45920", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1782, "end" : 2434, "hmmStart" : 513, "hmmEnd" : 1161, "hmmLength" : 1165, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1739, "envelopeEnd" : 2437, "location-fragments" : [ { "start" : 1782, "end" : 2434, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1371, "end" : 1706, "hmmStart" : 37, "hmmEnd" : 349, "hmmLength" : 1165, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1290, "envelopeEnd" : 1767, "location-fragments" : [ { "start" : 1371, "end" : 1706, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "FAMILY NOT NAMED", "score" : 1385.4, "model-ac" : "PTHR45920" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 668, "end" : 761, "location-fragments" : [ { "start" : 668, "end" : 761, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1043, "end" : 1139, "location-fragments" : [ { "start" : 1043, "end" : 1139, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909676.1 PREDICTED: uncharacterized protein LOC109038874 isoform X3 [Bemisia tabaci]", "id" : "XP_018909676.1" } ] },{ "sequence" : "MLPVRSSILFLCCAVISQVASAPNSPPAKLPKTFKRCKKLDPNLPDCLRTAVQGVIPEFVKGVPSLGVLPLDPLELKTLVIEQGDGPVSIKLDFKDLFIHGIASAVITSVTSNLKNYTINLTAELKKPIILDGMYNVHGKVLILPITGTGKCKLVLEGFRAKIGIKGKAITKNGIKYMEVQTFKFGLSTTKLRVKLENLFNGDKALGDNMNVFLNENWEDILKELQPGFEDSLSQAFLEISNRVFTKVPFDQIFLD", "md5" : "b8c5e5188979c719903c08b13934e42c", "matches" : [ { "signature" : { "accession" : "PTHR11008", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 255, "hmmStart" : 5, "hmmEnd" : 253, "hmmLength" : 254, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 256, "location-fragments" : [ { "start" : 7, "end" : 255, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-68, "familyName" : "RE08075P", "score" : 234.1, "model-ac" : "PTHR11008" }, { "signature" : { "accession" : "PTHR11008:SF38", "name" : "RE08075P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 255, "hmmStart" : 5, "hmmEnd" : 253, "hmmLength" : 254, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 256, "location-fragments" : [ { "start" : 7, "end" : 255, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-68, "familyName" : "RE08075P", "score" : 234.1, "model-ac" : "PTHR11008:SF38" }, { "signature" : { "accession" : "SM00700", "name" : "jhbp", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR010562", "name" : "Haemolymph_juvenile_hormone-bd", "description" : "Haemolymph juvenile hormone binding", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 28, "end" : 256, "hmmStart" : 1, "hmmEnd" : 243, "hmmLength" : 243, "hmmBounds" : "COMPLETE", "evalue" : 7.0E-64, "score" : 228.2, "location-fragments" : [ { "start" : 28, "end" : 256, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-64, "score" : 228.2, "model-ac" : "SM00700" }, { "signature" : { "accession" : "G3DSA:3.15.10.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR038606", "name" : "To_sf", "description" : "Takeout superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 33, "end" : 255, "hmmStart" : 5, "hmmEnd" : 217, "hmmLength" : 220, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-63, "score" : 215.5, "envelopeStart" : 33, "envelopeEnd" : 255, "postProcessed" : true, "location-fragments" : [ { "start" : 33, "end" : 255, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-63, "score" : 215.8, "model-ac" : "3e8tA00" }, { "signature" : { "accession" : "PF06585", "name" : "JHBP", "description" : "Haemolymph juvenile hormone binding protein (JHBP)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR010562", "name" : "Haemolymph_juvenile_hormone-bd", "description" : "Haemolymph juvenile hormone binding", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 16, "end" : 254, "hmmStart" : 7, "hmmEnd" : 238, "hmmLength" : 239, "hmmBounds" : "INCOMPLETE", "evalue" : 2.7E-77, "score" : 259.2, "envelopeStart" : 8, "envelopeEnd" : 255, "postProcessed" : true, "location-fragments" : [ { "start" : 16, "end" : 254, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-77, "score" : 259.3, "model-ac" : "PF06585" } ], "xref" : [ { "name" : "XP_018909796.1 PREDICTED: protein takeout-like [Bemisia tabaci]", "id" : "XP_018909796.1" } ] },{ "sequence" : "MEQAESANPQVWVFGYGSLCWHPGFEYEEAVTGYIKGYTRKFWQGSANHRGTSEKGIVWGRAFKLTGDLALHYLNDRECKLGGYTTLHLDFYPKPDALLSDSTDSISTSTSTSSASSSTSSEISASDSSSTGFSSATTELSTSNSTTAHSTPSSTEGSETTAISVLNSSSSSKPFKALVFIATPANDLWLGEAPLNDIADHIVGCKGQSGYNVEYVLRLAHFMHEHIPEAKDNHLFTLEYLLLNKIEAANLCLNEMMGTKATAGSAGSSRGTTDTALPAPPQASYQFSARVPSKKLRCLNI", "md5" : "db2c9a14c931f0e62e6b532ead34bf81", "matches" : [ { "signature" : { "accession" : "cd06661", "name" : "GGCT_like", "description" : "GGCT_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR013024", "name" : "GGCT-like", "description" : "Gamma-glutamyl cyclotransferase-like", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 93, "sites" : [ { "description" : "putative catalytic residue", "numLocations" : 1, "siteLocations" : [ { "start" : 78, "end" : 78, "residue" : "E" } ] }, { "description" : "putative active site pocket", "numLocations" : 7, "siteLocations" : [ { "start" : 84, "end" : 84, "residue" : "Y" }, { "start" : 78, "end" : 78, "residue" : "E" }, { "start" : 16, "end" : 16, "residue" : "Y" }, { "start" : 18, "end" : 18, "residue" : "S" }, { "start" : 19, "end" : 19, "residue" : "L" }, { "start" : 13, "end" : 13, "residue" : "V" }, { "start" : 77, "end" : 77, "residue" : "R" } ] } ], "evalue" : 4.22003E-11, "score" : 56.5842, "location-fragments" : [ { "start" : 13, "end" : 93, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd06661" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 135, "end" : 162, "location-fragments" : [ { "start" : 135, "end" : 162, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12192:SF2", "name" : "GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 6, "end" : 244, "hmmStart" : 5, "hmmEnd" : 180, "hmmLength" : 205, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 271, "location-fragments" : [ { "start" : 6, "end" : 244, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-50, "familyName" : "GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1", "score" : 173.5, "model-ac" : "PTHR12192:SF2" }, { "signature" : { "accession" : "PTHR12192", "name" : "CATION TRANSPORT PROTEIN CHAC-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006840", "name" : "ChaC", "description" : "Glutathione-specific gamma-glutamylcyclotransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "glutathione catabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006751" }, { "name" : "gamma-glutamylcyclotransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003839" } ], "pathwayXRefs" : [ { "name" : "5-oxo-L-proline metabolism", "databaseName" : "MetaCyc", "id" : "PWY-7942" }, { "name" : "Glutathione synthesis and recycling", "databaseName" : "Reactome", "id" : "R-HSA-174403" }, { "name" : "Glutathione metabolism", "databaseName" : "KEGG", "id" : "00480+4.3.2.7" } ] } }, "locations" : [ { "start" : 6, "end" : 244, "hmmStart" : 5, "hmmEnd" : 180, "hmmLength" : 205, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 271, "location-fragments" : [ { "start" : 6, "end" : 244, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-50, "familyName" : "GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1", "score" : 173.5, "model-ac" : "PTHR12192" }, { "signature" : { "accession" : "PF04752", "name" : "ChaC", "description" : "ChaC-like protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006840", "name" : "ChaC", "description" : "Glutathione-specific gamma-glutamylcyclotransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "glutathione catabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006751" }, { "name" : "gamma-glutamylcyclotransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003839" } ], "pathwayXRefs" : [ { "name" : "5-oxo-L-proline metabolism", "databaseName" : "MetaCyc", "id" : "PWY-7942" }, { "name" : "Glutathione synthesis and recycling", "databaseName" : "Reactome", "id" : "R-HSA-174403" }, { "name" : "Glutathione metabolism", "databaseName" : "KEGG", "id" : "00480+4.3.2.7" } ] } }, "locations" : [ { "start" : 11, "end" : 240, "hmmStart" : 1, "hmmEnd" : 176, "hmmLength" : 181, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.7E-43, "score" : 148.1, "envelopeStart" : 11, "envelopeEnd" : 245, "postProcessed" : true, "location-fragments" : [ { "start" : 11, "end" : 240, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-46, "score" : 157.2, "model-ac" : "PF04752" } ], "xref" : [ { "name" : "XP_018909873.1 PREDICTED: putative glutathione-specific gamma-glutamylcyclotransferase 2 isoform X2 [Bemisia tabaci]", "id" : "XP_018909873.1" } ] },{ "sequence" : "MAEDVSQKTPIVGDNSKLSKSSSRASSDIHCNCGDLDKVSGQPTPLSSGNNQKKKTSFQITSVTVGSRVSNDGGEDSADDLDESHTDDMSDVIDTSRVTDVENETPSFSEDTFSKEDVFFNSSTSLGSAPVIPTSSQYGLAIVSAPDICNNSNSSAQCGAISNNDLHVTVADSVLNLSVLGAKQHEADMRDLHNHPGRNERFKVVKIESTEPFKRGRWVCMDFLDHSIVQSKPNSISKPSDPSDNQSGLHTGNDSGISVADSNLVNDEPVSSDHVNSSNNHAQNEQITSASSGLNQSLPGQAQNVPGSNHTMSGQNHSVSAPPQSAPATHSNASPGQTLQFNPVNCSQPQQHAQSMSQIPLQQTPNFINQNQHQSLQAQQLQQALANANYQMQNATNSNQQQQHMNVNNVMQQSMPMQQHVQQQYQTSMPPPQVVQPIQVQNVPQQQFQQPQQPQQQQHQQVQMMQQIPVSQQQPAFVQQCTPVVGSQQPVVPQQPQPMPQQAQQYYTNPSVVHNSNALSNQVPIINSQNQNLTNMIPVHQPQQVVSTSQPQQIMTQQSQPQVISQPNSMQGQPQQTVPIISNSMPAQPQTQTNLIQSQPVMSQQSQAQPMMTQQNQIPNQPQQQMMSQNTVVQSQPQHMMAQPTTQQNQPQQMMGQQSNSQSQPSTLISIQTQPQQMMQQQAPIQTQQVISQQPANTVQPQQLLAQQMQSHMMSQASTPPVQSQPILTQTNLQSQPQQMMTQPSNQVQPQQLMNQQSNNIQPQQSVMPPQTMVQNQMMPQQMMAQPSMMPPTNHMTNQQANFTVTNIQPTNQPAQTQHLPNYPVSQPSSGHHYIPSSLNQQSYPSAMSMLNEVEISENKMIEQLGVQSTLVESLNDVQNTTNNGDEAQLEDHADSER", "md5" : "e0d65a8bc40a70de0be6702d9d385b3a", "matches" : [ { "signature" : { "accession" : "PTHR12348:SF25", "name" : "ZGC:153012", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 44, "end" : 104, "hmmStart" : 14, "hmmEnd" : 76, "hmmLength" : 329, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 38, "envelopeEnd" : 124, "location-fragments" : [ { "start" : 44, "end" : 104, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-17, "familyName" : "ZGC:153012", "score" : 67.0, "model-ac" : "PTHR12348:SF25" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 231, "end" : 375, "location-fragments" : [ { "start" : 231, "end" : 375, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 378, "end" : 398, "location-fragments" : [ { "start" : 378, "end" : 398, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 636, "end" : 663, "location-fragments" : [ { "start" : 636, "end" : 663, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 29, "location-fragments" : [ { "start" : 9, "end" : 29, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 868, "end" : 887, "location-fragments" : [ { "start" : 868, "end" : 887, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 90, "location-fragments" : [ { "start" : 1, "end" : 90, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 868, "end" : 898, "location-fragments" : [ { "start" : 868, "end" : 898, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12348", "name" : "TSC22", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 44, "end" : 104, "hmmStart" : 14, "hmmEnd" : 76, "hmmLength" : 329, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 38, "envelopeEnd" : 124, "location-fragments" : [ { "start" : 44, "end" : 104, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-17, "familyName" : "ZGC:153012", "score" : 67.0, "model-ac" : "PTHR12348" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 41, "end" : 71, "location-fragments" : [ { "start" : 41, "end" : 71, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910139.1 PREDICTED: putative mediator of RNA polymerase II transcription subunit 12 isoform X3 [Bemisia tabaci]", "id" : "XP_018910139.1" } ] },{ "sequence" : "MARTAQDREKSPKKKAKKRILESPKKKAKKRDYGSYASFVYKVLKQVHPAVGISKRAMVIMDSFVADIFERLATEAGKLCKKSNTRTISSREIQTATRLVIPGELCKHAVSEGTKAVTKYVSSKGTA", "md5" : "a3825a077118fa2b24558d58b5091c14", "matches" : [ { "signature" : { "accession" : "PS00357", "name" : "HISTONE_H2B", "description" : "Histone H2B signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000558", "name" : "Histone_H2B", "description" : "Histone H2B", "type" : "FAMILY", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" }, { "name" : "nucleosome", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0000786" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 91, "end" : 113, "level" : "STRONG", "cigarAlignment" : "5M2I1M1I2M1I3M1I7M", "alignment" : "REIQTatRlVIpGELcKHAVSEG", "location-fragments" : [ { "start" : 91, "end" : 113, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00357" }, { "signature" : { "accession" : "PTHR23428", "name" : "HISTONE H2B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR000558", "name" : "Histone_H2B", "description" : "Histone H2B", "type" : "FAMILY", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" }, { "name" : "nucleosome", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0000786" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 124, "hmmStart" : 9, "hmmEnd" : 126, "hmmLength" : 126, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 124, "location-fragments" : [ { "start" : 7, "end" : 124, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-46, "familyName" : "H2B HISTONE FAMILY, MEMBER M", "score" : 158.1, "model-ac" : "PTHR23428" }, { "signature" : { "accession" : "SM00427", "name" : "h2b3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000558", "name" : "Histone_H2B", "description" : "Histone H2B", "type" : "FAMILY", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" }, { "name" : "nucleosome", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0000786" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 26, "end" : 122, "hmmStart" : 1, "hmmEnd" : 97, "hmmLength" : 97, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-55, "score" : 199.7, "location-fragments" : [ { "start" : 26, "end" : 122, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-55, "score" : 199.7, "model-ac" : "SM00427" }, { "signature" : { "accession" : "PR00621", "name" : "HISTONEH2B", "description" : "Histone H2B signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000558", "name" : "Histone_H2B", "description" : "Histone H2B", "type" : "FAMILY", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" }, { "name" : "nucleosome", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0000786" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 55, "end" : 75, "pvalue" : 1.96E-10, "score" : 63.85, "motifNumber" : 2, "location-fragments" : [ { "start" : 55, "end" : 75, "dc-status" : "CONTINUOUS" } ] }, { "start" : 107, "end" : 120, "pvalue" : 5.4E-10, "score" : 95.85, "motifNumber" : 5, "location-fragments" : [ { "start" : 107, "end" : 120, "dc-status" : "CONTINUOUS" } ] }, { "start" : 94, "end" : 107, "pvalue" : 6.79E-9, "score" : 71.5, "motifNumber" : 4, "location-fragments" : [ { "start" : 94, "end" : 107, "dc-status" : "CONTINUOUS" } ] }, { "start" : 77, "end" : 94, "pvalue" : 9.04E-6, "score" : 45.61, "motifNumber" : 3, "location-fragments" : [ { "start" : 77, "end" : 94, "dc-status" : "CONTINUOUS" } ] }, { "start" : 36, "end" : 54, "pvalue" : 1.8E-10, "score" : 66.62, "motifNumber" : 1, "location-fragments" : [ { "start" : 36, "end" : 54, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-36, "graphscan" : "IIIII", "model-ac" : "PR00621" }, { "signature" : { "accession" : "PF00125", "name" : "Histone", "description" : "Core histone H2A/H2B/H3/H4", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR007125", "name" : "Histone_H2A/H2B/H3", "description" : "Histone H2A/H2B/H3", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 99, "hmmStart" : 35, "hmmEnd" : 130, "hmmLength" : 131, "hmmBounds" : "INCOMPLETE", "evalue" : 2.3E-17, "score" : 63.6, "envelopeStart" : 1, "envelopeEnd" : 100, "postProcessed" : true, "location-fragments" : [ { "start" : 8, "end" : 99, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-17, "score" : 63.9, "model-ac" : "PF00125" }, { "signature" : { "accession" : "G3DSA:1.10.20.10", "name" : "Histone", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR009072", "name" : "Histone-fold", "description" : "Histone-fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein heterodimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046982" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 124, "hmmStart" : 13, "hmmEnd" : 129, "hmmLength" : 129, "hmmBounds" : "COMPLETE", "evalue" : 7.6E-49, "score" : 166.9, "envelopeStart" : 1, "envelopeEnd" : 124, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 124, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-49, "score" : 167.0, "model-ac" : "2rvqD00" }, { "signature" : { "accession" : "SSF47113", "name" : "Histone-fold", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009072", "name" : "Histone-fold", "description" : "Histone-fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein heterodimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046982" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 124, "hmmLength" : 122, "location-fragments" : [ { "start" : 8, "end" : 124, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.34E-43, "model-ac" : "0047904" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 27, "location-fragments" : [ { "start" : 1, "end" : 27, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR23428:SF159", "name" : "H2B HISTONE FAMILY, MEMBER M", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 124, "hmmStart" : 9, "hmmEnd" : 126, "hmmLength" : 126, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 124, "location-fragments" : [ { "start" : 7, "end" : 124, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-46, "familyName" : "H2B HISTONE FAMILY, MEMBER M", "score" : 158.1, "model-ac" : "PTHR23428:SF159" } ], "xref" : [ { "name" : "XP_018910100.1 PREDICTED: late histone H2B.L4-like [Bemisia tabaci]", "id" : "XP_018910100.1" } ] },{ "sequence" : "MSVRKGFCWVVLCLGVVAAQGFPSAPQSNSVWSGTPMDAVVEDLRLECARENDGVSCIKFKVLGLLDQALRKDSFKVGDDIKIVKNSGSDSTSETESRGFSDQIESYIQNHDVEVQVPGSLFKGTVLTFSPRNLDKDELNLSVKLPSEENSALGTDRGRKSKLKKILIPILVFILLKALTLIPLAIGVLGLKAWNALQLSFFSFVVSVALAIFQLCKKIAADNAIPQLTAHPWADHYAAARNLFLTPEELEQPLTAADASSPDAQDLAFNAYNALSRRR", "md5" : "b9eee438f54f02bd34bad862eb6dc94d", "matches" : [ { "signature" : { "accession" : "PF07898", "name" : "DUF1676", "description" : "Protein of unknown function (DUF1676)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR012464", "name" : "DUF1676", "description" : "Protein of unknown function DUF1676", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 47, "end" : 213, "hmmStart" : 1, "hmmEnd" : 171, "hmmLength" : 172, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.7E-26, "score" : 92.7, "envelopeStart" : 47, "envelopeEnd" : 214, "postProcessed" : true, "location-fragments" : [ { "start" : 47, "end" : 213, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.8E-27, "score" : 94.1, "model-ac" : "PF07898" }, { "signature" : { "accession" : "PTHR21879", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR012464", "name" : "DUF1676", "description" : "Protein of unknown function DUF1676", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 239, "hmmStart" : 5, "hmmEnd" : 218, "hmmLength" : 239, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 273, "location-fragments" : [ { "start" : 13, "end" : 239, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-73, "familyName" : "OSIRIS 19, ISOFORM A", "score" : 248.1, "model-ac" : "PTHR21879" }, { "signature" : { "accession" : "PTHR21879:SF6", "name" : "OSIRIS 19, ISOFORM A", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 13, "end" : 239, "hmmStart" : 5, "hmmEnd" : 218, "hmmLength" : 239, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 273, "location-fragments" : [ { "start" : 13, "end" : 239, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-73, "familyName" : "OSIRIS 19, ISOFORM A", "score" : 248.1, "model-ac" : "PTHR21879:SF6" } ], "xref" : [ { "name" : "XP_018909773.1 PREDICTED: uncharacterized protein LOC109038950 isoform X2 [Bemisia tabaci]", "id" : "XP_018909773.1" } ] },{ "sequence" : "MQVRMGNKMDLLLQRWNFMTRSGLTLLTMLVCCASQLQPTAEPEFYFLHPCSRSDPRINDCLTYAANNLAMHFRKGIPELEITNVEPIVIDEINLALGSGPDGYRATFRDIEAFGVSNLTVTQVRSDLSSLQFQLSFYIPKISAKARYRSSGVLIMVQATGGGDYWGEYEGVKAKVYFRASEYQAEGRSYLQVEDLKMDFSVKSIQMGIQNVHNGNAVIEAALNLFINSNAQDLLREMKPSIKRKLLVTMKGFIDNLFSRIPYDSWIVD", "md5" : "1aa6be326fcafe7005e55cf8e84d7f0b", "matches" : [ { "signature" : { "accession" : "PF06585", "name" : "JHBP", "description" : "Haemolymph juvenile hormone binding protein (JHBP)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR010562", "name" : "Haemolymph_juvenile_hormone-bd", "description" : "Haemolymph juvenile hormone binding", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 30, "end" : 267, "hmmStart" : 3, "hmmEnd" : 238, "hmmLength" : 239, "hmmBounds" : "INCOMPLETE", "evalue" : 1.0E-66, "score" : 224.6, "envelopeStart" : 26, "envelopeEnd" : 268, "postProcessed" : true, "location-fragments" : [ { "start" : 30, "end" : 267, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-67, "score" : 224.8, "model-ac" : "PF06585" }, { "signature" : { "accession" : "PTHR11008:SF31", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 28, "end" : 267, "hmmStart" : 9, "hmmEnd" : 247, "hmmLength" : 248, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 19, "envelopeEnd" : 268, "location-fragments" : [ { "start" : 28, "end" : 267, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-114, "familyName" : "", "score" : 384.1, "model-ac" : "PTHR11008:SF31" }, { "signature" : { "accession" : "PTHR11008", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 28, "end" : 267, "hmmStart" : 9, "hmmEnd" : 247, "hmmLength" : 248, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 19, "envelopeEnd" : 268, "location-fragments" : [ { "start" : 28, "end" : 267, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-114, "familyName" : "", "score" : 384.1, "model-ac" : "PTHR11008" }, { "signature" : { "accession" : "G3DSA:3.15.10.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR038606", "name" : "To_sf", "description" : "Takeout superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 47, "end" : 267, "hmmStart" : 4, "hmmEnd" : 216, "hmmLength" : 220, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-43, "score" : 150.7, "envelopeStart" : 47, "envelopeEnd" : 267, "postProcessed" : true, "location-fragments" : [ { "start" : 47, "end" : 267, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-43, "score" : 151.1, "model-ac" : "3e8tA00" }, { "signature" : { "accession" : "SM00700", "name" : "jhbp", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR010562", "name" : "Haemolymph_juvenile_hormone-bd", "description" : "Haemolymph juvenile hormone binding", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 269, "hmmStart" : 1, "hmmEnd" : 243, "hmmLength" : 243, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-57, "score" : 206.4, "location-fragments" : [ { "start" : 42, "end" : 269, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-57, "score" : 206.4, "model-ac" : "SM00700" } ], "xref" : [ { "name" : "XP_018910316.1 PREDICTED: protein takeout-like [Bemisia tabaci]", "id" : "XP_018910316.1" } ] },{ "sequence" : "MRECFAHGTRQCLTCKCTTHNKTDCLDSLCSQIKDAKIAGEYSNIYSHSSQPSISLSQTRRNSLPNDKLNTASKYSNPQAARSANFSIPHMSANNSTSAPQSNNLPPNQTTNSNNMSSKRDEELEFLRNQNSQLLSQVQQLTSQLNTMSQQISELVASSQSQNNNNSKRPRDSTNDSPRKIKKVPSLAQKQLFADQNKFANLSDDMDEDSAEDDNDISLGSDDGIFINPGNLNPVVNSAINRIKKTKAVAKKTKTIEKNKINDKKDDNNSNPNVSVTTSSANSINSSQSTENKTRKLKKPPPIYTAIKTNFNDLCKALNKIDSTKWSSTVLSNDSFKINSIDDETHNLIIKELQTVNIYFNTFENKNIRPIRVLVKGLHHDTSVTNIINSLKASGFKPLNATANLKRIVEYPGKNQSDTPLNVSATSKETDKSTNTTPDSVPNNEISANDPQLVTIDSDASAEPSGGDAKVEGTQGKTGNDTNLQSIPPVIKYQPLNTFTVSFDHSDNIEKIFEIKTIANMRVMIEPIPSNSPLTPIQCKKCQGYNHSSNFCNYPPRCVKCSGEHMSFLCEKPKYIPDPKCVNCGGNHAASYRGCLIAKTITEQRRELFKKIEEKKAIRTGQQVTPAASTLKKGVSFRDAFRNDRSFPKLNNTSQEPATANQNDNSTNSQNPQHQPQDRFDELFATMSQILDSVNNLAQRVATLENKLQVRPDSTQRSLK", "md5" : "ccec07b56df46ec7b66d651b57958194", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 124, "end" : 158, "location-fragments" : [ { "start" : 124, "end" : 158, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 268, "end" : 291, "location-fragments" : [ { "start" : 268, "end" : 291, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 642, "end" : 681, "location-fragments" : [ { "start" : 642, "end" : 681, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 152, "end" : 217, "location-fragments" : [ { "start" : 152, "end" : 217, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 416, "end" : 483, "location-fragments" : [ { "start" : 416, "end" : 483, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 53, "end" : 128, "location-fragments" : [ { "start" : 53, "end" : 128, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 687, "end" : 707, "location-fragments" : [ { "start" : 687, "end" : 707, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 152, "end" : 171, "location-fragments" : [ { "start" : 152, "end" : 171, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 53, "end" : 117, "location-fragments" : [ { "start" : 53, "end" : 117, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 646, "end" : 677, "location-fragments" : [ { "start" : 646, "end" : 677, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 416, "end" : 459, "location-fragments" : [ { "start" : 416, "end" : 459, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 254, "end" : 300, "location-fragments" : [ { "start" : 254, "end" : 300, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910285.1 PREDICTED: rho GTPase-activating protein gacF-like [Bemisia tabaci]", "id" : "XP_018910285.1" } ] },{ "sequence" : "MRKKSKRNPFSPSTFCIRGKSRNRNGDRASSDKVLWAEENNYINYGEEDQMEVYGYASSFIRKMSIWILMCLTCGIVRLVFHWWPEWMLYATHRRCPLNEAEKILVINNYEGHIISHFVKDVKLISIHDLSSDSTKDKDRISGLDIQALVQLQSNLRSKKLKAFLFDGSRKAREFPKINSLRNLDRYVFLKLHVIWHSESIMVSTKIRISVFHQAGRNYETG", "md5" : "96614c2c0309f165331696c8986fa0c2", "matches" : [ { "signature" : { "accession" : "PF12409", "name" : "P5-ATPase", "description" : "P5-type ATPase cation transporter", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006544", "name" : "P-type_TPase_V", "description" : "P-type ATPase, subfamily V", "type" : "FAMILY", "goXRefs" : [ { "name" : "ATPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016887" }, { "name" : "cation transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006812" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ { "name" : "Ion transport by P-type ATPases", "databaseName" : "Reactome", "id" : "R-HSA-936837" } ] } }, "locations" : [ { "start" : 47, "end" : 134, "hmmStart" : 1, "hmmEnd" : 85, "hmmLength" : 126, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.2E-21, "score" : 77.0, "envelopeStart" : 47, "envelopeEnd" : 173, "postProcessed" : true, "location-fragments" : [ { "start" : 47, "end" : 134, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-22, "score" : 77.6, "model-ac" : "PF12409" }, { "signature" : { "accession" : "PTHR45630", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 39, "end" : 199, "hmmStart" : 16, "hmmEnd" : 160, "hmmLength" : 1160, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 20, "envelopeEnd" : 214, "location-fragments" : [ { "start" : 39, "end" : 199, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.4E-15, "familyName" : "CATION-TRANSPORTING ATPASE 13A2", "score" : 56.1, "model-ac" : "PTHR45630" }, { "signature" : { "accession" : "PTHR45630:SF2", "name" : "CATION-TRANSPORTING ATPASE 13A2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 39, "end" : 199, "hmmStart" : 16, "hmmEnd" : 160, "hmmLength" : 1160, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 20, "envelopeEnd" : 214, "location-fragments" : [ { "start" : 39, "end" : 199, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.4E-15, "familyName" : "CATION-TRANSPORTING ATPASE 13A2", "score" : 56.1, "model-ac" : "PTHR45630:SF2" } ], "xref" : [ { "name" : "XP_018909881.1 PREDICTED: probable cation-transporting ATPase 13A5 isoform X1 [Bemisia tabaci]", "id" : "XP_018909881.1" } ] },{ "sequence" : "MASRTTLALISSLALIISLPGGGCILSSLLDGLSAAGAQAGTAASDIGQASLDTLATGTKGLHRMVKFGTKTLTEYHTNSLDYLVGGHKRAAKMIDDGIGGLAELGQKIGVQVRDTAFTGTKQAGRVGVDLAKSGVNLLNRAATGATGTLKTVLQESAGRVLQALPKTPILTPIIEMPYDMAHSTLDALTEMANDSAQNTHNILDKFRPDVPDDENP", "md5" : "ad533ae84c14d854fef81db6deb5a71e", "matches" : [ ], "xref" : [ { "name" : "XP_018910128.1 PREDICTED: uncharacterized protein LOC109039191 [Bemisia tabaci]", "id" : "XP_018910128.1" } ] },{ "sequence" : "MANAPQQGEAPAQNRNENDGPLMRDMRCIVCLDREREIMFLPCRHFAVCEPCNEVLIRQVPPMQDQRCPTCREPVIDAVRVFVA", "md5" : "849cb49bc6e54744432a446c9944af89", "matches" : [ { "signature" : { "accession" : "G3DSA:3.30.40.10", "name" : "Zinc/RING finger domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013083", "name" : "Znf_RING/FYVE/PHD", "description" : "Zinc finger, RING/FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3, "end" : 84, "hmmStart" : 12, "hmmEnd" : 73, "hmmLength" : 74, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-17, "score" : 63.9, "envelopeStart" : 3, "envelopeEnd" : 84, "postProcessed" : true, "location-fragments" : [ { "start" : 3, "end" : 84, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-17, "score" : 64.0, "model-ac" : "3eb5A00" }, { "signature" : { "accession" : "PS50089", "name" : "ZF_RING_2", "description" : "Zinc finger RING-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 28, "end" : 72, "score" : 10.306, "alignment" : "CIVCLDREREI--MFLPCRHFaVCEPCNEVLirqVPPMQDQRCPTCR", "location-fragments" : [ { "start" : 28, "end" : 72, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50089" }, { "signature" : { "accession" : "PTHR22696", "name" : "RING FINGER PROTEIN 26 RNF26", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 82, "hmmStart" : 472, "hmmEnd" : 527, "hmmLength" : 528, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 83, "location-fragments" : [ { "start" : 25, "end" : 82, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-18, "familyName" : "RING FINGER PROTEIN 26 RNF26", "score" : 69.8, "model-ac" : "PTHR22696" }, { "signature" : { "accession" : "SSF57850", "name" : "RING/U-box", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 23, "end" : 77, "hmmLength" : 56, "location-fragments" : [ { "start" : 23, "end" : 77, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.13E-9, "model-ac" : "0035646" }, { "signature" : { "accession" : "SM00184", "name" : "ring_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 28, "end" : 71, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.0014, "score" : 27.9, "location-fragments" : [ { "start" : 28, "end" : 71, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0014, "score" : 27.9, "model-ac" : "SM00184" }, { "signature" : { "accession" : "PF13920", "name" : "zf-C3HC4_3", "description" : "Zinc finger, C3HC4 type (RING finger)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 76, "hmmStart" : 2, "hmmEnd" : 48, "hmmLength" : 50, "hmmBounds" : "INCOMPLETE", "evalue" : 1.7E-14, "score" : 53.4, "envelopeStart" : 24, "envelopeEnd" : 78, "postProcessed" : true, "location-fragments" : [ { "start" : 25, "end" : 76, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-14, "score" : 53.7, "model-ac" : "PF13920" } ], "xref" : [ { "name" : "XP_018909889.1 PREDICTED: ring finger protein 26-like [Bemisia tabaci]", "id" : "XP_018909889.1" } ] },{ "sequence" : "DLQAEIESHRDVFSSLSGSGRSLLSSLGSQEDAVMLQRRLDEMNQRWHHLKARSMAIRNRLESNAEHWNALLLSLRELVEWVIRKDTELTGLGPIATDVNALQKQQDDYRAFRRQLEDKRPVVESNLFSGKQYIASEPPLSDTSDQE", "md5" : "9747fd0c2560eec52cb4662c385afe28", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 99, "end" : 119, "location-fragments" : [ { "start" : 99, "end" : 119, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "G3DSA:1.20.58.60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 71, "end" : 147, "hmmStart" : 10, "hmmEnd" : 78, "hmmLength" : 118, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-6, "score" : 30.0, "envelopeStart" : 71, "envelopeEnd" : 147, "postProcessed" : true, "location-fragments" : [ { "start" : 71, "end" : 147, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-16, "score" : 62.4, "model-ac" : "3uulA00" }, { "signature" : { "accession" : "PF00435", "name" : "Spectrin", "description" : "Spectrin repeat", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002017", "name" : "Spectrin_repeat", "description" : "Spectrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 62, "hmmStart" : 45, "hmmEnd" : 104, "hmmLength" : 105, "hmmBounds" : "INCOMPLETE", "evalue" : 1.2E-5, "score" : 25.7, "envelopeStart" : 1, "envelopeEnd" : 63, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 62, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-11, "score" : 43.9, "model-ac" : "PF00435" }, { "signature" : { "accession" : "G3DSA:1.20.58.60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 60, "hmmStart" : 44, "hmmEnd" : 94, "hmmLength" : 102, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-7, "score" : 34.1, "envelopeStart" : 1, "envelopeEnd" : 60, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 60, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-11, "score" : 45.7, "model-ac" : "1s35A01" }, { "signature" : { "accession" : "PTHR12268", "name" : "E3 UBIQUITIN-PROTEIN LIGASE KCMF1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 145, "hmmStart" : 320, "hmmEnd" : 464, "hmmLength" : 1231, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 147, "location-fragments" : [ { "start" : 1, "end" : 145, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.9E-54, "familyName" : "E3 UBIQUITIN-PROTEIN LIGASE KCMF1", "score" : 185.8, "model-ac" : "PTHR12268" }, { "signature" : { "accession" : "SSF46966", "name" : "Spectrin repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 13, "end" : 142, "hmmLength" : 156, "location-fragments" : [ { "start" : 13, "end" : 142, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-20, "model-ac" : "0048652" } ], "xref" : [ { "name" : "XP_018910417.1 PREDICTED: dystrophin-like, partial [Bemisia tabaci]", "id" : "XP_018910417.1" } ] },{ "sequence" : "MDAEWFWRHSKYYVQLLIFFLALSFEFAESFDYKNNQMAPIILVPGVAGTKIEAKYHTTGHPRGCDEDSDWELIWINLKAAAGGLPLRCWVYRYRLFYDRAAHRCRNQAGVETRVMGRFGSLKPVDYLTKDPFSRIGTNYFNDMSDALKDSGYSTDINLKAAGYDGRYAPLQQKEFGYFDRFTELVEKVATDSKRKVSIVSHSMGGLVAAYFLGLKSQEWKDKYIHNFVAVSTPWLGSVFALESYILGTNYGVPTFKKSLMKELVRTFQSVAFLLPAEEAFGETVLVDWTLKNKKYTAKDYKELFTDLQYEDGYLMREDVRSFFPVDIDKLGVKVVCIYSNLNKIETLQRYEIADDILNPKSVKSHFVEGDGTVTLNSLQHCDKFKNVTVKVFQGYDHLKIIFKDDVIDFIQSVTVNAQSL", "md5" : "45b7ed116d0a20b3d9fcdc624c33ba00", "matches" : [ { "signature" : { "accession" : "PTHR11440", "name" : "LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 414, "hmmStart" : 42, "hmmEnd" : 410, "hmmLength" : 420, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 10, "envelopeEnd" : 419, "location-fragments" : [ { "start" : 35, "end" : 414, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.7E-70, "familyName" : "BCDNA.GH02384", "score" : 238.4, "model-ac" : "PTHR11440" }, { "signature" : { "accession" : "SSF53474", "name" : "alpha/beta-Hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 39, "end" : 408, "hmmLength" : 388, "location-fragments" : [ { "start" : 140, "end" : 408, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 39, "end" : 52, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.6E-22, "model-ac" : "0047879" }, { "signature" : { "accession" : "PF02450", "name" : "LCAT", "description" : "Lecithin:cholesterol acyltransferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR003386", "name" : "LACT/PDAT_acylTrfase", "description" : "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "lipid metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006629" }, { "name" : "O-acyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008374" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 73, "end" : 286, "hmmStart" : 5, "hmmEnd" : 214, "hmmLength" : 392, "hmmBounds" : "INCOMPLETE", "evalue" : 5.3E-41, "score" : 141.1, "envelopeStart" : 71, "envelopeEnd" : 329, "postProcessed" : true, "location-fragments" : [ { "start" : 73, "end" : 286, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.7E-44, "score" : 150.1, "model-ac" : "PF02450" }, { "signature" : { "accession" : "PTHR11440:SF35", "name" : "BCDNA.GH02384", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 414, "hmmStart" : 42, "hmmEnd" : 410, "hmmLength" : 420, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 10, "envelopeEnd" : 419, "location-fragments" : [ { "start" : 35, "end" : 414, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.7E-70, "familyName" : "BCDNA.GH02384", "score" : 238.4, "model-ac" : "PTHR11440:SF35" } ], "xref" : [ { "name" : "XP_018909748.1 PREDICTED: phosphatidylcholine-sterol acyltransferase-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909748.1" } ] },{ "sequence" : "MIGETIDSKPVKNGKLLDPLRSFMLYRHFLGGSLMIIVYHLSFNSAQTLEETVVLKDLEEKLETQKFKEIFDKPLENTIELQWDHGKYIVKAGDKVDIEKVYEKPTSVIWDADLDYYYTLVLYDYDAPLRVHPHLRSFVHWMIGNIPEKNLTAGTTFYDYYGLKLFEKGGR", "md5" : "8438797e89d31d87778852353246c0bb", "matches" : [ { "signature" : { "accession" : "PF01161", "name" : "PBP", "description" : "Phosphatidylethanolamine-binding protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR008914", "name" : "PEBP", "description" : "Phosphatidylethanolamine-binding protein", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 117, "end" : 153, "hmmStart" : 26, "hmmEnd" : 60, "hmmLength" : 132, "hmmBounds" : "INCOMPLETE", "evalue" : 6.6E-5, "score" : 23.2, "envelopeStart" : 77, "envelopeEnd" : 168, "postProcessed" : true, "location-fragments" : [ { "start" : 117, "end" : 153, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-5, "score" : 24.2, "model-ac" : "PF01161" }, { "signature" : { "accession" : "G3DSA:3.90.280.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 53, "end" : 170, "hmmStart" : 10, "hmmEnd" : 112, "hmmLength" : 190, "hmmBounds" : "COMPLETE", "evalue" : 6.7E-21, "score" : 76.7, "envelopeStart" : 53, "envelopeEnd" : 170, "postProcessed" : true, "location-fragments" : [ { "start" : 53, "end" : 170, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-21, "score" : 77.1, "model-ac" : "2iqyA00" }, { "signature" : { "accession" : "SSF49777", "name" : "PEBP-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 68, "end" : 162, "hmmLength" : 180, "location-fragments" : [ { "start" : 68, "end" : 162, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.83E-16, "model-ac" : "0040158" }, { "signature" : { "accession" : "PTHR11362:SF28", "name" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 71, "end" : 162, "hmmStart" : 22, "hmmEnd" : 111, "hmmLength" : 193, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 44, "envelopeEnd" : 169, "location-fragments" : [ { "start" : 71, "end" : 162, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-18, "familyName" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "score" : 70.0, "model-ac" : "PTHR11362:SF28" }, { "signature" : { "accession" : "PTHR11362", "name" : "PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR035810", "name" : "PEBP_euk", "description" : "Phosphatidylethanolamine-binding protein, eukaryotic", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 71, "end" : 162, "hmmStart" : 22, "hmmEnd" : 111, "hmmLength" : 193, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 44, "envelopeEnd" : 169, "location-fragments" : [ { "start" : 71, "end" : 162, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-18, "familyName" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "score" : 70.0, "model-ac" : "PTHR11362" } ], "xref" : [ { "name" : "XP_018909758.1 PREDICTED: putative odorant-binding protein A5 [Bemisia tabaci]", "id" : "XP_018909758.1" } ] },{ "sequence" : "MAFGARTVSIAAFLCVTTVIAEPSPVQEQNRNLNPPQQWVARAIAEHIWNYQLTSEKNPECTRHFNIYREHLSNFTLWAVQMLDASDVVPSGLLAADIFKLGNFEECINTKVPTEYGFTAQYCLPTINFNRTNLEISTKHENEWEDPVWIKILNSRDRRKAPKDRFTFALCIPSTCSSEDLKISLQSSLEVPLREAAYDINVTLDNLLCTTMEGPPGSLGSMIMKYFLVGLTGLFLFCSITDLVLAGARGDDYDITNFSFSKAVGIQKWLLPFSLCRNVFQLTAQPTSPDEYRILHGLKATLMMFIIMAHIALFRCGKVPFVNWSYTEDKMARSSITYIIGGLLPDVFFCMTGFTVCQSMLNQLEKGSFNVRTHIANKLLRVLPPYIFVIACMIFVLPYLGSGPIWRTFIEPEVEFCRNNWWLNLLFVNNYFRIGEWCLPQSYYIAADMHFFIVGSLIVYLCWRWAPYKLVILGSALFLTFLLPFLTVFRNEYNGFLRLDYEFLTDQFRKQPEVQHVYMKSHCRSGGYIVGITAAFVLRHFKKTDCKLSKGMSWAGVLFAVCILFGTLLAKYVLYNSSPSLMIRAIHTGLSTQLIGGAFMIVIVIQITSDLGAWNKILFTQDVFIPFSRITYWLYLLNVPIVMALIGSLKTPIHMTYEETGFLGRHLGDFFPIYAFAIYGYLTIEAPITHLKPKILRFISGSPSPTDKKNQ", "md5" : "e905ba53859dcdc46b8eeeeb52f4bfbd", "matches" : [ { "signature" : { "accession" : "PTHR11161", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 50, "end" : 693, "hmmStart" : 39, "hmmEnd" : 618, "hmmLength" : 633, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 12, "envelopeEnd" : 698, "location-fragments" : [ { "start" : 50, "end" : 693, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-82, "familyName" : "UNCHARACTERIZED", "score" : 280.1, "model-ac" : "PTHR11161" }, { "signature" : { "accession" : "SM00703", "name" : "nrf", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006621", "name" : "Nose-resist-to-fluoxetine_N", "description" : "Nose resistant-to-fluoxetine protein, N-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 58, "end" : 201, "hmmStart" : 1, "hmmEnd" : 178, "hmmLength" : 178, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-5, "score" : 27.8, "location-fragments" : [ { "start" : 58, "end" : 201, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-5, "score" : 27.8, "model-ac" : "SM00703" }, { "signature" : { "accession" : "PF01757", "name" : "Acyl_transf_3", "description" : "Acyltransferase family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002656", "name" : "Acyl_transf_3", "description" : "Acyltransferase 3", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transferase activity, transferring acyl groups other than amino-acyl groups", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016747" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 295, "end" : 649, "hmmStart" : 4, "hmmEnd" : 311, "hmmLength" : 340, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-15, "score" : 57.0, "envelopeStart" : 292, "envelopeEnd" : 681, "postProcessed" : true, "location-fragments" : [ { "start" : 295, "end" : 649, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-15, "score" : 57.6, "model-ac" : "PF01757" } ], "xref" : [ { "name" : "XP_018909879.1 PREDICTED: nose resistant to fluoxetine protein 6-like [Bemisia tabaci]", "id" : "XP_018909879.1" }, { "name" : "XP_018909875.1 PREDICTED: nose resistant to fluoxetine protein 6-like [Bemisia tabaci]", "id" : "XP_018909875.1" }, { "name" : "XP_018909874.1 PREDICTED: nose resistant to fluoxetine protein 6-like [Bemisia tabaci]", "id" : "XP_018909874.1" }, { "name" : "XP_018909878.1 PREDICTED: nose resistant to fluoxetine protein 6-like [Bemisia tabaci]", "id" : "XP_018909878.1" } ] },{ "sequence" : "MAHSLHLLGFPPRKVRSRKNKENMESTDSPESTEMESTKGTESTKKTRRTKSTKGKKRTRSTKTKSTESKKPKSTRSTKTKSTKITKTKKNTKTPKIKKSARNTRLPRISKSTESTKISKTTEVIGSTEILTTTRHETTRSRPKIISPFDAIFRENEIVPQIVNNTPIYKCEVEYGKEKIHFGNNMTADQIAEKPTLIKWPTQSGAFYTLLMFGPDVPTREKSCEMMWRHWAVGNIPKNDIDKGDTLVEYENIEPFYRAGFHRILFFIYKQPGRRRLNFTSSKGVIKKGSKWEVRGVWYIERFLAKFNLTEPIAANFFFLYDLNPHPEIPHVTVDPLSLIR", "md5" : "0dc65b4e265df9a91315788ba7581054", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 76, "end" : 105, "location-fragments" : [ { "start" : 76, "end" : 105, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 117, "location-fragments" : [ { "start" : 1, "end" : 117, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF01161", "name" : "PBP", "description" : "Phosphatidylethanolamine-binding protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR008914", "name" : "PEBP", "description" : "Phosphatidylethanolamine-binding protein", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 195, "end" : 287, "hmmStart" : 13, "hmmEnd" : 103, "hmmLength" : 132, "hmmBounds" : "INCOMPLETE", "evalue" : 2.5E-6, "score" : 27.9, "envelopeStart" : 177, "envelopeEnd" : 317, "postProcessed" : true, "location-fragments" : [ { "start" : 195, "end" : 287, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-6, "score" : 28.6, "model-ac" : "PF01161" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 49, "end" : 64, "location-fragments" : [ { "start" : 49, "end" : 64, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF49777", "name" : "PEBP-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 153, "end" : 319, "hmmLength" : 185, "location-fragments" : [ { "start" : 153, "end" : 319, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-32, "model-ac" : "0034862" }, { "signature" : { "accession" : "G3DSA:3.90.280.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 148, "end" : 324, "hmmStart" : 12, "hmmEnd" : 173, "hmmLength" : 190, "hmmBounds" : "COMPLETE", "evalue" : 3.7E-41, "score" : 142.8, "envelopeStart" : 148, "envelopeEnd" : 324, "postProcessed" : true, "location-fragments" : [ { "start" : 148, "end" : 324, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-41, "score" : 143.6, "model-ac" : "2iqyA00" }, { "signature" : { "accession" : "cd00866", "name" : "PEBP_euk", "description" : "PEBP_euk", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR035810", "name" : "PEBP_euk", "description" : "Phosphatidylethanolamine-binding protein, eukaryotic", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 172, "end" : 319, "sites" : [ { "description" : "substrate binding site", "numLocations" : 9, "siteLocations" : [ { "start" : 228, "end" : 228, "residue" : "W" }, { "start" : 254, "end" : 254, "residue" : "E" }, { "start" : 253, "end" : 253, "residue" : "I" }, { "start" : 264, "end" : 264, "residue" : "I" }, { "start" : 230, "end" : 230, "residue" : "H" }, { "start" : 262, "end" : 262, "residue" : "H" }, { "start" : 214, "end" : 214, "residue" : "G" }, { "start" : 255, "end" : 255, "residue" : "P" }, { "start" : 256, "end" : 256, "residue" : "F" } ] } ], "evalue" : 9.10243E-33, "score" : 117.474, "location-fragments" : [ { "start" : 172, "end" : 319, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00866" }, { "signature" : { "accession" : "PTHR11362", "name" : "PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR035810", "name" : "PEBP_euk", "description" : "Phosphatidylethanolamine-binding protein, eukaryotic", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 149, "end" : 319, "hmmStart" : 8, "hmmEnd" : 173, "hmmLength" : 193, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 143, "envelopeEnd" : 334, "location-fragments" : [ { "start" : 149, "end" : 319, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-39, "familyName" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "score" : 136.2, "model-ac" : "PTHR11362" }, { "signature" : { "accession" : "PTHR11362:SF28", "name" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 149, "end" : 319, "hmmStart" : 8, "hmmEnd" : 173, "hmmLength" : 193, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 143, "envelopeEnd" : 334, "location-fragments" : [ { "start" : 149, "end" : 319, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-39, "familyName" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "score" : 136.2, "model-ac" : "PTHR11362:SF28" } ], "xref" : [ { "name" : "XP_018910110.1 PREDICTED: uncharacterized protein LOC109039182 isoform X2 [Bemisia tabaci]", "id" : "XP_018910110.1" }, { "name" : "XP_018910111.1 PREDICTED: uncharacterized protein LOC109039182 isoform X2 [Bemisia tabaci]", "id" : "XP_018910111.1" } ] },{ "sequence" : "MCDKGSSSGCFFTRKGRETQVDLATSPRRQPQINNTNMGPRPKDPLPMVVQGDFRKVSGISNEIFRQIETIENELDGSIAAALASVERRGEMVVRMLDYRSMGKNAAELAKRFLSMQDAQHSVHFVEIVKRPGQTLGLYIREGNGVDRADGVFISRIALESAVYNSGCLKVGDEILAVNLVDVTRMSLDDVVIIMSIPRRLVLATRQVKGLRQAQGTPSQPRALELKVPPVVVIKKSLTREEDQDDEEDEENNHRFADLNRESKIRGRVGQSRSHLALGSLDTNGDIGSGALYYNSRPHAATLDRRMGNSDNKSWSYQPPPPPVVTQQPKPQHFQPFDKSYPNTLESLAEKVHPFNPGNGPGSSYGAGSSRYATTGRSSSRLSNRGPSMPRSGSDQHLPRVEYDYGNGLPARHSGSLLRSSLRASTGMGGSYSRSRDQYNASPSSTLLPRRQRPALDYASDTEATCSSSSRASYYYCRPSPPVSSLTRGVSFRSNSLPRHSLTSQSSGRTPLSVRFERNNLLDEGDSDGALSAPELPIARKHRGRLSSTPSVFTSDEYRAWLSRTPSTSAIYDRLRAGQQKAQRFTFSAENLPERTRQSELLASYRSSGLSALTGLSGLTSSTLDRHTLANRTTSLRRMRHLLELEAKHQADRAKIMEINPAEFLKYKMEKWNGPEPVGASGLLWVHLLAGRGLRNPSPSQTTGNRDLYCVLECDRVHKARTVVRTGDLVFDWDETFELDLVGNKQLDFLIYSWDPQYRHKLCYKGSVHLASLLRDSPIHQLALKIEPRGTLYLRLRHTSPYRTFLRQSRSATGLFGGDLEATVAREGGSIPIIVRRCVEEVERRGLDIIGLYRLCGSATKKRILREAFERNARIVDLSPDHVPDINVITGVLKDYLRELPEPLFTKCLYQMMVDALTVCLPDDPEGNAKLMFSILDCLPRINKATLVFLLDHLAMVVGASGRNKMCSGSVASCLAPVLILHSESATDPMDFMQPISVLRYLLDIWPNKSGYNTILLTIPTSYNQLQVVFNS", "md5" : "1983ec737bb06c27e5b4d887161f7204", "matches" : [ { "signature" : { "accession" : "G3DSA:1.10.555.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR008936", "name" : "Rho_GTPase_activation_prot", "description" : "Rho GTPase activation protein", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 814, "end" : 1011, "hmmStart" : 3, "hmmEnd" : 191, "hmmLength" : 208, "hmmBounds" : "COMPLETE", "evalue" : 7.5E-50, "score" : 171.0, "envelopeStart" : 814, "envelopeEnd" : 1011, "postProcessed" : true, "location-fragments" : [ { "start" : 814, "end" : 1011, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-50, "score" : 171.8, "model-ac" : "4u3kA00" }, { "signature" : { "accession" : "PS50238", "name" : "RHOGAP", "description" : "Rho GTPase-activating proteins domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 818, "end" : 1010, "score" : 38.893, "alignment" : "GDLEATVAREGGSIPIIVRRCVEEVERRGLDIIGLYRLCGSATKKRILREAFERNARIVDLSPDhvpDINVITGVLKDYLRELPEPLFTKCLYQMMVDaltVCLPDDPEGNAKLMFSILDCLPRINKATLVFLLDHLAMVVGASGRNKMCSGSVASCLAPVLILHSE-SATDPMDFMQPISVLRYLLDIWPNKS", "location-fragments" : [ { "start" : 818, "end" : 1010, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50238" }, { "signature" : { "accession" : "SSF50156", "name" : "PDZ domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036034", "name" : "PDZ_sf", "description" : "PDZ superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 118, "end" : 198, "hmmLength" : 124, "location-fragments" : [ { "start" : 118, "end" : 198, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.59E-16, "model-ac" : "0050541" }, { "signature" : { "accession" : "G3DSA:2.60.40.150", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR035892", "name" : "C2_domain_sf", "description" : "C2 domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 680, "end" : 804, "hmmStart" : 6, "hmmEnd" : 126, "hmmLength" : 143, "hmmBounds" : "COMPLETE", "evalue" : 5.8E-11, "score" : 44.5, "envelopeStart" : 680, "envelopeEnd" : 804, "postProcessed" : true, "location-fragments" : [ { "start" : 680, "end" : 804, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-11, "score" : 45.5, "model-ac" : "4npkA01" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 497, "end" : 520, "location-fragments" : [ { "start" : 497, "end" : 520, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR46150:SF3", "name" : "RHO GTPASE-ACTIVATING PROTEIN 100F", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 47, "end" : 1011, "hmmStart" : 6, "hmmEnd" : 956, "hmmLength" : 1027, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 38, "envelopeEnd" : 1024, "location-fragments" : [ { "start" : 47, "end" : 1011, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "RHO GTPASE-ACTIVATING PROTEIN 100F", "score" : 1129.4, "model-ac" : "PTHR46150:SF3" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 427, "end" : 449, "location-fragments" : [ { "start" : 427, "end" : 449, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00239", "name" : "C2_3c", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000008", "name" : "C2_dom", "description" : "C2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 683, "end" : 782, "hmmStart" : 1, "hmmEnd" : 92, "hmmLength" : 92, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-4, "score" : 30.1, "location-fragments" : [ { "start" : 683, "end" : 782, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-4, "score" : 30.1, "model-ac" : "SM00239" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 497, "end" : 514, "location-fragments" : [ { "start" : 497, "end" : 514, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00228", "name" : "pdz_new", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 134, "end" : 209, "hmmStart" : 1, "hmmEnd" : 80, "hmmLength" : 80, "hmmBounds" : "COMPLETE", "evalue" : 4.7E-8, "score" : 42.7, "location-fragments" : [ { "start" : 134, "end" : 209, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-8, "score" : 42.7, "model-ac" : "SM00228" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 362, "end" : 391, "location-fragments" : [ { "start" : 362, "end" : 391, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF49562", "name" : "C2 domain (Calcium/lipid-binding domain, CaLB)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 681, "end" : 799, "hmmLength" : 136, "location-fragments" : [ { "start" : 681, "end" : 799, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.07E-16, "model-ac" : "0038166" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 253, "end" : 268, "location-fragments" : [ { "start" : 253, "end" : 268, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 303, "end" : 407, "location-fragments" : [ { "start" : 303, "end" : 407, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 39, "location-fragments" : [ { "start" : 19, "end" : 39, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00324", "name" : "RhoGAP_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 829, "end" : 1007, "hmmStart" : 1, "hmmEnd" : 193, "hmmLength" : 193, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-40, "score" : 148.9, "location-fragments" : [ { "start" : 829, "end" : 1007, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-40, "score" : 148.9, "model-ac" : "SM00324" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 40, "location-fragments" : [ { "start" : 18, "end" : 40, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00992", "name" : "PDZ_signaling", "description" : "PDZ_signaling", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 123, "end" : 203, "sites" : [ { "description" : "protein binding site", "numLocations" : 9, "siteLocations" : [ { "start" : 138, "end" : 138, "residue" : "L" }, { "start" : 137, "end" : 137, "residue" : "G" }, { "start" : 140, "end" : 140, "residue" : "I" }, { "start" : 136, "end" : 136, "residue" : "L" }, { "start" : 195, "end" : 195, "residue" : "M" }, { "start" : 191, "end" : 191, "residue" : "V" }, { "start" : 194, "end" : 194, "residue" : "I" }, { "start" : 135, "end" : 135, "residue" : "T" }, { "start" : 192, "end" : 192, "residue" : "V" } ] } ], "evalue" : 8.4819E-15, "score" : 68.3622, "location-fragments" : [ { "start" : 123, "end" : 203, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00992" }, { "signature" : { "accession" : "PS50106", "name" : "PDZ", "description" : "PDZ domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 125, "end" : 195, "score" : 13.692, "alignment" : "FVEIVKRPGQTLGLYIREGNGVDRADGVFISRIALESAVYNSGCLKVGDEILAVNLVDVTRMSLDDVVIIM---------------", "location-fragments" : [ { "start" : 125, "end" : 195, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50106" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 237, "end" : 268, "location-fragments" : [ { "start" : 237, "end" : 268, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00030", "name" : "C2", "description" : "C2", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 684, "end" : 786, "sites" : [ ], "evalue" : 1.63654E-10, "score" : 57.0767, "location-fragments" : [ { "start" : 684, "end" : 786, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00030" }, { "signature" : { "accession" : "G3DSA:2.30.42.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036034", "name" : "PDZ_sf", "description" : "PDZ superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 110, "end" : 224, "hmmStart" : 20, "hmmEnd" : 108, "hmmLength" : 128, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-16, "score" : 62.1, "envelopeStart" : 110, "envelopeEnd" : 224, "postProcessed" : true, "location-fragments" : [ { "start" : 110, "end" : 224, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.9E-17, "score" : 63.1, "model-ac" : "1uf1A00" }, { "signature" : { "accession" : "PF00620", "name" : "RhoGAP", "description" : "RhoGAP domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 832, "end" : 985, "hmmStart" : 1, "hmmEnd" : 149, "hmmLength" : 152, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.1E-37, "score" : 127.0, "envelopeStart" : 832, "envelopeEnd" : 988, "postProcessed" : true, "location-fragments" : [ { "start" : 832, "end" : 985, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-37, "score" : 128.0, "model-ac" : "PF00620" }, { "signature" : { "accession" : "PF00595", "name" : "PDZ", "description" : "PDZ domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 129, "end" : 196, "hmmStart" : 5, "hmmEnd" : 71, "hmmLength" : 82, "hmmBounds" : "INCOMPLETE", "evalue" : 2.1E-10, "score" : 40.8, "envelopeStart" : 126, "envelopeEnd" : 204, "postProcessed" : true, "location-fragments" : [ { "start" : 129, "end" : 196, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-10, "score" : 41.6, "model-ac" : "PF00595" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 427, "end" : 462, "location-fragments" : [ { "start" : 427, "end" : 462, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF48350", "name" : "GTPase activation domain, GAP", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR008936", "name" : "Rho_GTPase_activation_prot", "description" : "Rho GTPase activation protein", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 815, "end" : 1006, "hmmLength" : 196, "location-fragments" : [ { "start" : 815, "end" : 1006, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.18E-44, "model-ac" : "0050892" }, { "signature" : { "accession" : "PTHR46150", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 47, "end" : 1011, "hmmStart" : 6, "hmmEnd" : 956, "hmmLength" : 1027, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 38, "envelopeEnd" : 1024, "location-fragments" : [ { "start" : 47, "end" : 1011, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "RHO GTPASE-ACTIVATING PROTEIN 100F", "score" : 1129.4, "model-ac" : "PTHR46150" } ], "xref" : [ { "name" : "XP_018910343.1 PREDICTED: rho GTPase-activating protein 100F-like isoform X6 [Bemisia tabaci]", "id" : "XP_018910343.1" } ] },{ "sequence" : "MDFGGPIQTRTSTLRNSKVVKTYICVFVCFSTKAVHIETTSDLTTNSFIAALTRFICRRGKPSDLWSDCGSNFLGASNELQKITREFFNAPQNLEIINRFSIANSIKFHNNPPAAPEQGGLWEGAIKSVKTHLKRVVGTHLLTREEFDTLMSKIEAMLNSRPLTPLSQDPSEIDVLTPGHFLIGTTLTALPERPLLDISNNRLKRWETVQAFSQRVRKRWYLEYLTKLQQREKWAKKQPYLKVGDLVLLIEPNAPPLQWPLARVSKVCPGKDNLVRVAEVKTENSTFTRPVSKLCPLPME", "md5" : "c68f03d8b5f969a530ecec26d7b184f5", "matches" : [ { "signature" : { "accession" : "PS50994", "name" : "INTEGRASE", "description" : "Integrase catalytic domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001584", "name" : "Integrase_cat-core", "description" : "Integrase, catalytic core", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA integration", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0015074" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 186, "score" : 11.072, "alignment" : "----------MDFGGPIQTRtstlrnskVVKTYICVFVCFSTKAVHIETTSDLTTNSFIAALTRFICRR-GKPSDLWSDCGSNFlgasnelqkitreffnapqNLEIINRFSIANSIKFHNNPPAAPEQGGLWEGAIKSVKTHLKRVVGTHLltREEFDTLMSKIEAMLNSRPLtplsqdpSEIDVLTPGHFLIGTT", "location-fragments" : [ { "start" : 1, "end" : 186, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50994" }, { "signature" : { "accession" : "PTHR22955", "name" : "RETROTRANSPOSON", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 293, "hmmStart" : 1196, "hmmEnd" : 1456, "hmmLength" : 1456, "hmmBounds" : "COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 293, "location-fragments" : [ { "start" : 1, "end" : 293, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-73, "familyName" : "", "score" : 251.2, "model-ac" : "PTHR22955" }, { "signature" : { "accession" : "SSF53098", "name" : "Ribonuclease H-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR012337", "name" : "RNaseH-like_sf", "description" : "Ribonuclease H-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 172, "hmmLength" : 168, "location-fragments" : [ { "start" : 1, "end" : 172, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.95E-16, "model-ac" : "0046055" }, { "signature" : { "accession" : "PTHR22955:SF60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 293, "hmmStart" : 1196, "hmmEnd" : 1456, "hmmLength" : 1456, "hmmBounds" : "COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 293, "location-fragments" : [ { "start" : 1, "end" : 293, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-73, "familyName" : "", "score" : 251.2, "model-ac" : "PTHR22955:SF60" }, { "signature" : { "accession" : "G3DSA:3.30.420.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036397", "name" : "RNaseH_sf", "description" : "Ribonuclease H superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 185, "hmmStart" : 18, "hmmEnd" : 159, "hmmLength" : 200, "hmmBounds" : "COMPLETE", "evalue" : 4.1E-11, "score" : 44.4, "envelopeStart" : 1, "envelopeEnd" : 185, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 185, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-12, "score" : 47.2, "model-ac" : "2x78A00" }, { "signature" : { "accession" : "PF18701", "name" : "DUF5641", "description" : "Family of unknown function (DUF5641)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR040676", "name" : "DUF5641", "description" : "Domain of unknown function DUF5641", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 204, "end" : 297, "hmmStart" : 1, "hmmEnd" : 94, "hmmLength" : 94, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-35, "score" : 121.5, "envelopeStart" : 204, "envelopeEnd" : 297, "postProcessed" : true, "location-fragments" : [ { "start" : 204, "end" : 297, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-36, "score" : 122.3, "model-ac" : "PF18701" } ], "xref" : [ { "name" : "XP_018910144.1 PREDICTED: uncharacterized protein LOC109039207 [Bemisia tabaci]", "id" : "XP_018910144.1" } ] },{ "sequence" : "MAPRRNNHSVALHAPAAGHTATANEIGHFFLDPLSLDQDNYTHCCVPSGECLHHQQPIPLNDLEDAVKVVCNNDNCTMGKFMHRECFEHWEQSVLNYLKTCGRARSWSERQRHQNLWTKKGYDLAFKACGCKCGRGHLKKDLDWVPSSGSVFREDTDTSKKKKRKNKSNARPTLAISAAHANGNLPNMGHIGNIGTKSFENHILSADLRTRTGSLSSSTGSSSPPASTSSISPVHSSGTGASKRKIKFDFFSDRHISSMNGSGIFTRRQDFTSFNSIPKVKLNSYNIKMEDEGNHGNDDTRCFVLSTLAAKHQPRVNCLLCHSTMLVFDRYPLVDGTFFLSPKQHSHFSIETKSEGKTQYLSAVCMGCLQGWTKLRCRHCSEPWDGSSLMIGSMYSYDIFAAMPCCADRLKCNGCQKALLLPHQRLNFYSDYSHKVACPQCGVQDNHFVKPLASCFTRGWP", "md5" : "f30941a86b4590e7e5a5c34e1f9aa0b1", "matches" : [ { "signature" : { "accession" : "PF15353", "name" : "HECA", "description" : "Headcase protein family homologue", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR026066", "name" : "Headcase", "description" : "Headcase protein", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 43, "end" : 144, "hmmStart" : 1, "hmmEnd" : 102, "hmmLength" : 102, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-49, "score" : 166.4, "envelopeStart" : 43, "envelopeEnd" : 144, "postProcessed" : true, "location-fragments" : [ { "start" : 43, "end" : 144, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-50, "score" : 167.8, "model-ac" : "PF15353" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 154, "end" : 181, "location-fragments" : [ { "start" : 154, "end" : 181, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR13425", "name" : "HEADCASE PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR026066", "name" : "Headcase", "description" : "Headcase protein", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 40, "end" : 457, "hmmStart" : 65, "hmmEnd" : 513, "hmmLength" : 524, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 35, "envelopeEnd" : 459, "location-fragments" : [ { "start" : 40, "end" : 457, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.4E-162, "familyName" : "HEADCASE PROTEIN", "score" : 542.8, "model-ac" : "PTHR13425" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 210, "end" : 238, "location-fragments" : [ { "start" : 210, "end" : 238, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF16002", "name" : "Headcase", "description" : "Headcase protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR031947", "name" : "Headcase_mid", "description" : "Headcase, middle domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 258, "end" : 452, "hmmStart" : 3, "hmmEnd" : 198, "hmmLength" : 198, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.8E-96, "score" : 320.7, "envelopeStart" : 256, "envelopeEnd" : 452, "postProcessed" : true, "location-fragments" : [ { "start" : 258, "end" : 452, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-96, "score" : 320.7, "model-ac" : "PF16002" } ], "xref" : [ { "name" : "XP_018910461.1 PREDICTED: headcase protein [Bemisia tabaci]", "id" : "XP_018910461.1" } ] },{ "sequence" : "MCDKGSSSGCFFTRKGRETQVDLATSPRRQPQINNTNMGPRPKDPLPMVVQGDFRKVSGISNEIFRQIETIENELDGSIAAALASVERRGEMVVRMLDYRSMGKNAAELAKRFLSMQDAQHSVHFVEIVKRPGQTLGLYIREGNGVDRADGVFISRIALESAVYNSGCLKVGDEILAVNLVDVTRMSLDDVVIIMSIPRRLVLATRQVKGLRQAQGTPSQPRALELKVPPVVVIKKSLTREEDQDDEEDEENNHRFADLNRESKIRGRVGQSRSHLALGSLDTNGDIGSGALYYNSRPHAATLDRRMGNSDNKSWSYQPPPPPVVTQQPKPQHFQPFDKSYPNTLESLAEKVHPFNPGNGPGSSYGAGSSRYATTGRSSSRLSNRGPSMPRSGSDQHLPRVEYDYGNGLPARHSGSLLRSSLRASTGMGGSYSRSRDQYNASPSSTLLPRRQRPALDYASDTEATCSSSSRASYYYCRPSPPVSSLTRGVSFRSNSLPRHSLTSQSSGRTPLSVRFERNNLLDEGDSDGALSAPELPIARKHRGRLSSTPSVFTSDEYRAWLSRTPSTSAIYDRLRAGQQKAQRFTFSAENLPERTRQSELLASYRSSGLSALTGLSGLTSSTLDRHTLANRTTSLRRMRHLLELEAKHQADRAKIMEINPAEFLKYKMEKWNGPEPVGASGLLWVHLLAGRGLRNPSPSQTTGNRDLYCVLECDRVHKARTVVRTGDLVFDWDETFELDLVGNKQLDFLIYSWDPQYRHKLCYKGSVHLASLLRDSPIHQLALKIEPRGTLYLRLRHTSPYRTFLRQSRSATGLFGGDLEATVAREGGSIPIIVRRCVEEVERRGLDIIGLYRLCGSATKKRILREAFERNARIVDLSPDHVPDINVITGVLKDYLRELPEPLFTKCLYQMMVDALTVCLPDDPEGNAKLMFSILDCLPRINKATLVFLLDHLAMVVGASGRNKMCSGSVASCLAPVLILHSESATDPMDFMQPISVLRYLLDIWPNKSVRDSVGHPVRPSKCLLPQQPPPLPAKPVGFRQTSGPVVVASPTSDTSPEENDEQDDVVSVIQAHTDSKPSPLDTSRSDANLINSLAQSVVTSSNPENGNSIANIIERFNQTTKTSNLSAPGSPATVARGINYGQPPKLPPRNNISTLGNTTVVNSVTSSSNLFANSPSNYLKDKNILSSANNLHTTNGNNSSINELPERNGLSNGTKSGRENNPFLCDPKPPPIAARNILSEGNSDILQNNVFSNSIFQRENNISGGATSNGARLFSYSPAISSAADTATNHDASYSYTNVFAKTNPFQTENMLRINVTSSLDISSGNLPTRLSSQHSPISPGQRDVETPSSSTGTEEDSRRERGVDADQESSEEDLK", "md5" : "f2d98e1164733c18ff8696da508591cd", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1197, "end" : 1221, "location-fragments" : [ { "start" : 1197, "end" : 1221, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR46150", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 47, "end" : 1122, "hmmStart" : 6, "hmmEnd" : 957, "hmmLength" : 1027, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 38, "envelopeEnd" : 1365, "location-fragments" : [ { "start" : 47, "end" : 1122, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "RHO GTPASE-ACTIVATING PROTEIN 100F", "score" : 1138.1, "model-ac" : "PTHR46150" }, { "signature" : { "accession" : "G3DSA:1.10.555.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR008936", "name" : "Rho_GTPase_activation_prot", "description" : "Rho GTPase activation protein", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 814, "end" : 1013, "hmmStart" : 3, "hmmEnd" : 191, "hmmLength" : 208, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-49, "score" : 170.5, "envelopeStart" : 814, "envelopeEnd" : 1013, "postProcessed" : true, "location-fragments" : [ { "start" : 814, "end" : 1013, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-50, "score" : 171.3, "model-ac" : "4u3kA00" }, { "signature" : { "accession" : "PTHR46150:SF3", "name" : "RHO GTPASE-ACTIVATING PROTEIN 100F", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 47, "end" : 1122, "hmmStart" : 6, "hmmEnd" : 957, "hmmLength" : 1027, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 38, "envelopeEnd" : 1365, "location-fragments" : [ { "start" : 47, "end" : 1122, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "RHO GTPASE-ACTIVATING PROTEIN 100F", "score" : 1138.1, "model-ac" : "PTHR46150:SF3" }, { "signature" : { "accession" : "G3DSA:2.60.40.150", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR035892", "name" : "C2_domain_sf", "description" : "C2 domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 680, "end" : 803, "hmmStart" : 6, "hmmEnd" : 126, "hmmLength" : 143, "hmmBounds" : "COMPLETE", "evalue" : 8.8E-11, "score" : 43.9, "envelopeStart" : 680, "envelopeEnd" : 803, "postProcessed" : true, "location-fragments" : [ { "start" : 680, "end" : 803, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-11, "score" : 44.9, "model-ac" : "4npkA01" }, { "signature" : { "accession" : "PS50238", "name" : "RHOGAP", "description" : "Rho GTPase-activating proteins domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 818, "end" : 1010, "score" : 38.893, "alignment" : "GDLEATVAREGGSIPIIVRRCVEEVERRGLDIIGLYRLCGSATKKRILREAFERNARIVDLSPDhvpDINVITGVLKDYLRELPEPLFTKCLYQMMVDaltVCLPDDPEGNAKLMFSILDCLPRINKATLVFLLDHLAMVVGASGRNKMCSGSVASCLAPVLILHSE-SATDPMDFMQPISVLRYLLDIWPNKS", "location-fragments" : [ { "start" : 818, "end" : 1010, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50238" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1355, "end" : 1372, "location-fragments" : [ { "start" : 1355, "end" : 1372, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 497, "end" : 520, "location-fragments" : [ { "start" : 497, "end" : 520, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1042, "end" : 1087, "location-fragments" : [ { "start" : 1042, "end" : 1087, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 427, "end" : 449, "location-fragments" : [ { "start" : 427, "end" : 449, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00239", "name" : "C2_3c", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000008", "name" : "C2_dom", "description" : "C2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 683, "end" : 782, "hmmStart" : 1, "hmmEnd" : 92, "hmmLength" : 92, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-4, "score" : 30.1, "location-fragments" : [ { "start" : 683, "end" : 782, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-4, "score" : 30.1, "model-ac" : "SM00239" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 497, "end" : 514, "location-fragments" : [ { "start" : 497, "end" : 514, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00228", "name" : "pdz_new", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 134, "end" : 209, "hmmStart" : 1, "hmmEnd" : 80, "hmmLength" : 80, "hmmBounds" : "COMPLETE", "evalue" : 4.7E-8, "score" : 42.7, "location-fragments" : [ { "start" : 134, "end" : 209, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-8, "score" : 42.7, "model-ac" : "SM00228" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 362, "end" : 391, "location-fragments" : [ { "start" : 362, "end" : 391, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:2.30.42.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036034", "name" : "PDZ_sf", "description" : "PDZ superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 111, "end" : 224, "hmmStart" : 20, "hmmEnd" : 108, "hmmLength" : 128, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-16, "score" : 61.5, "envelopeStart" : 111, "envelopeEnd" : 224, "postProcessed" : true, "location-fragments" : [ { "start" : 111, "end" : 224, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-16, "score" : 62.6, "model-ac" : "1uf1A00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1068, "end" : 1087, "location-fragments" : [ { "start" : 1068, "end" : 1087, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 253, "end" : 268, "location-fragments" : [ { "start" : 253, "end" : 268, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF48350", "name" : "GTPase activation domain, GAP", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR008936", "name" : "Rho_GTPase_activation_prot", "description" : "Rho GTPase activation protein", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 815, "end" : 1006, "hmmLength" : 196, "location-fragments" : [ { "start" : 815, "end" : 1006, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.81E-44, "model-ac" : "0050892" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1197, "end" : 1224, "location-fragments" : [ { "start" : 1197, "end" : 1224, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 303, "end" : 407, "location-fragments" : [ { "start" : 303, "end" : 407, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 39, "location-fragments" : [ { "start" : 19, "end" : 39, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00324", "name" : "RhoGAP_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 829, "end" : 1007, "hmmStart" : 1, "hmmEnd" : 193, "hmmLength" : 193, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-40, "score" : 148.9, "location-fragments" : [ { "start" : 829, "end" : 1007, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-40, "score" : 148.9, "model-ac" : "SM00324" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 40, "location-fragments" : [ { "start" : 18, "end" : 40, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1327, "end" : 1354, "location-fragments" : [ { "start" : 1327, "end" : 1354, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00620", "name" : "RhoGAP", "description" : "RhoGAP domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 832, "end" : 984, "hmmStart" : 1, "hmmEnd" : 148, "hmmLength" : 152, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 7.7E-37, "score" : 126.4, "envelopeStart" : 832, "envelopeEnd" : 988, "postProcessed" : true, "location-fragments" : [ { "start" : 832, "end" : 984, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-37, "score" : 127.6, "model-ac" : "PF00620" }, { "signature" : { "accession" : "cd00992", "name" : "PDZ_signaling", "description" : "PDZ_signaling", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 123, "end" : 203, "sites" : [ { "description" : "protein binding site", "numLocations" : 9, "siteLocations" : [ { "start" : 138, "end" : 138, "residue" : "L" }, { "start" : 137, "end" : 137, "residue" : "G" }, { "start" : 140, "end" : 140, "residue" : "I" }, { "start" : 136, "end" : 136, "residue" : "L" }, { "start" : 195, "end" : 195, "residue" : "M" }, { "start" : 191, "end" : 191, "residue" : "V" }, { "start" : 194, "end" : 194, "residue" : "I" }, { "start" : 135, "end" : 135, "residue" : "T" }, { "start" : 192, "end" : 192, "residue" : "V" } ] } ], "evalue" : 7.50394E-15, "score" : 68.7474, "location-fragments" : [ { "start" : 123, "end" : 203, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00992" }, { "signature" : { "accession" : "PS50106", "name" : "PDZ", "description" : "PDZ domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 125, "end" : 195, "score" : 13.692, "alignment" : "FVEIVKRPGQTLGLYIREGNGVDRADGVFISRIALESAVYNSGCLKVGDEILAVNLVDVTRMSLDDVVIIM---------------", "location-fragments" : [ { "start" : 125, "end" : 195, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50106" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 237, "end" : 268, "location-fragments" : [ { "start" : 237, "end" : 268, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00030", "name" : "C2", "description" : "C2", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 684, "end" : 786, "sites" : [ ], "evalue" : 2.21221E-10, "score" : 57.0767, "location-fragments" : [ { "start" : 684, "end" : 786, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00030" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1327, "end" : 1378, "location-fragments" : [ { "start" : 1327, "end" : 1378, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00595", "name" : "PDZ", "description" : "PDZ domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 129, "end" : 195, "hmmStart" : 5, "hmmEnd" : 70, "hmmLength" : 82, "hmmBounds" : "INCOMPLETE", "evalue" : 3.2E-10, "score" : 40.2, "envelopeStart" : 126, "envelopeEnd" : 203, "postProcessed" : true, "location-fragments" : [ { "start" : 129, "end" : 195, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-10, "score" : 41.4, "model-ac" : "PF00595" }, { "signature" : { "accession" : "SSF49562", "name" : "C2 domain (Calcium/lipid-binding domain, CaLB)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 681, "end" : 799, "hmmLength" : 136, "location-fragments" : [ { "start" : 681, "end" : 799, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.77E-16, "model-ac" : "0038166" }, { "signature" : { "accession" : "SSF50156", "name" : "PDZ domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036034", "name" : "PDZ_sf", "description" : "PDZ superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 118, "end" : 198, "hmmLength" : 124, "location-fragments" : [ { "start" : 118, "end" : 198, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.99E-16, "model-ac" : "0050541" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 427, "end" : 462, "location-fragments" : [ { "start" : 427, "end" : 462, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910338.1 PREDICTED: rho GTPase-activating protein 100F-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910338.1" } ] },{ "sequence" : "MISLKLALVLLSLSASALSVSVTSSLKPSDRAKFKQIFTASLDSNDVASVYYSVLGLKDLGEAIPKQQAICALVANSLKTTTSVENSFYASSTYQALSNCKETIHVANLIKKFKDVLADSTSSVPDLYFAAQGLKDLNQAVPHTDVVKTIQTALKTDDTLVNLGYVFHIASFLGSNGAFAYNRIEDAIVQADEVDGKFLQFEGGLSITALIINGAYKLGTSLNKAPQLSPDQAIKFANYFLSRRSVQLPKGAYFLLNVLKTLADNKFQIPVVIEIAETATISSSNPSLNVHVSDVLGNALTAPLTVTAESATRLSDNVVVLSKKKLEQTPANSKIYGVNILDAKLDAGLYRVSISAVPNKADPRLIGNVGTTVIIKVTCPVSVQNVQIGIVDSDQTSAPKLNDLVFPTRLGSVLSADVSQRLILKFGLKNKASGKALSVHQAFVKFTNLASQQEITFLAESSSDNNYKFDIDFNSKSSLFEHKSGDYMISLIVGDAILSDSFLWDMAKVQLKFPSDAPDAAKSSTDIYKPKPEIQHLFREPEPRPRAAVSTFFTGLVILPLLILLGLWVKLGVNIKNFPFSLSAVLFHLGLGAIFGLFTLFWLKLNMFETLKYLIGLAIVTFLCGNKMLSHVAANRKR", "md5" : "b09872ecfbcb514dd056fb227005e71e", "matches" : [ { "signature" : { "accession" : "PF05817", "name" : "Ribophorin_II", "description" : "Oligosaccharyltransferase subunit Ribophorin II", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR008814", "name" : "Swp1", "description" : "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1", "type" : "FAMILY", "goXRefs" : [ { "name" : "protein N-linked glycosylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006487" }, { "name" : "oligosaccharyltransferase complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0008250" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ { "name" : "Asparagine N-linked glycosylation", "databaseName" : "Reactome", "id" : "R-HSA-446203" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" } ] } }, "locations" : [ { "start" : 8, "end" : 634, "hmmStart" : 3, "hmmEnd" : 632, "hmmLength" : 633, "hmmBounds" : "INCOMPLETE", "evalue" : 7.2E-219, "score" : 728.5, "envelopeStart" : 5, "envelopeEnd" : 635, "postProcessed" : true, "location-fragments" : [ { "start" : 8, "end" : 634, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-219, "score" : 728.8, "model-ac" : "PF05817" }, { "signature" : { "accession" : "PTHR12640", "name" : "RIBOPHORIN II", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR008814", "name" : "Swp1", "description" : "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1", "type" : "FAMILY", "goXRefs" : [ { "name" : "protein N-linked glycosylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006487" }, { "name" : "oligosaccharyltransferase complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0008250" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ { "name" : "Asparagine N-linked glycosylation", "databaseName" : "Reactome", "id" : "R-HSA-446203" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" } ] } }, "locations" : [ { "start" : 7, "end" : 637, "hmmStart" : 6, "hmmEnd" : 636, "hmmLength" : 641, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 638, "location-fragments" : [ { "start" : 7, "end" : 637, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-200, "familyName" : "DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2", "score" : 671.2, "model-ac" : "PTHR12640" }, { "signature" : { "accession" : "PTHR12640:SF0", "name" : "DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 637, "hmmStart" : 6, "hmmEnd" : 636, "hmmLength" : 641, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 638, "location-fragments" : [ { "start" : 7, "end" : 637, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-200, "familyName" : "DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2", "score" : 671.2, "model-ac" : "PTHR12640:SF0" } ], "xref" : [ { "name" : "XP_018909835.1 PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 [Bemisia tabaci]", "id" : "XP_018909835.1" } ] },{ "sequence" : "NLTGLLHHSTHYLCLQDCNHDGKINCYDYAAIHKLGGYGCSGLGAENPYYRKFDQCARLIYNQSALPSAPTQPTYPNSPPQAEFSQESQHFGQQIQQQPHYPPPQPQYPPQPPQYPPQQSQFPTPPPQYPPQPQYPPQQSQYPPQQPQYPVKPQPGPIKPQKPGNKPQQIQQPYPQPPQQPYPQPFPQQPPQQFPQPPQSYPKPPPPQQGTYPPPPPAQQGSYPQPPQQQFPSQYPQPPQQQYPQKPPQQVYQPPQKPPQQAFQPQPPNNQIYQPGQQQFQQKPPVGYPQPAPQPGGGGYGNSLDNFELLPTPAVVVKSPGDGTTDDLDAFVYPTSVASFDSSSGSLTTYDTSGALTSYDKPSVLTSSSY", "md5" : "c6e69186873f14b16e3a7ad9d5038219", "matches" : [ { "signature" : { "accession" : "PS51909", "name" : "LYSOZYME_I", "description" : "Invertebrate (I)-type lysozyme domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 59, "score" : 12.04, "alignment" : "-----------------------------------------------------------------------NltGLLHHSTHYLCLQDCNHdgkiNCYDYAAIHKLGGYGCSGLgAENPYYRKFDQCARL", "location-fragments" : [ { "start" : 1, "end" : 59, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51909" }, { "signature" : { "accession" : "cd16890", "name" : "lyz_i", "description" : "lyz_i", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 56, "sites" : [ ], "evalue" : 2.31507E-11, "score" : 58.5128, "location-fragments" : [ { "start" : 16, "end" : 56, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd16890" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 78, "end" : 98, "location-fragments" : [ { "start" : 78, "end" : 98, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS00018", "name" : "EF_HAND_1", "description" : "EF-hand calcium-binding domain.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018247", "name" : "EF_Hand_1_Ca_BS", "description" : "EF-Hand 1, calcium-binding site", "type" : "BINDING_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 17, "end" : 29, "level" : "STRONG", "cigarAlignment" : "9M2I2M", "alignment" : "DCNHDGKINcyDY", "location-fragments" : [ { "start" : 17, "end" : 29, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00018" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 99, "end" : 162, "location-fragments" : [ { "start" : 99, "end" : 162, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.10.530.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 60, "hmmStart" : 78, "hmmEnd" : 116, "hmmLength" : 122, "hmmBounds" : "COMPLETE", "evalue" : 4.7E-8, "score" : 35.0, "envelopeStart" : 8, "envelopeEnd" : 60, "postProcessed" : true, "location-fragments" : [ { "start" : 8, "end" : 60, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-8, "score" : 35.7, "model-ac" : "4pj2C00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 67, "end" : 311, "location-fragments" : [ { "start" : 67, "end" : 311, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 266, "end" : 285, "location-fragments" : [ { "start" : 266, "end" : 285, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 170, "end" : 265, "location-fragments" : [ { "start" : 170, "end" : 265, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF05497", "name" : "Destabilase", "description" : "Destabilase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR008597", "name" : "Invert_lysozyme", "description" : "Invertebrate-type lysozyme", "type" : "FAMILY", "goXRefs" : [ { "name" : "lysozyme activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003796" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 16, "end" : 56, "hmmStart" : 77, "hmmEnd" : 118, "hmmLength" : 118, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.8E-7, "score" : 31.5, "envelopeStart" : 9, "envelopeEnd" : 56, "postProcessed" : true, "location-fragments" : [ { "start" : 16, "end" : 56, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-7, "score" : 32.1, "model-ac" : "PF05497" } ], "xref" : [ { "name" : "XP_018910140.1 PREDICTED: calcium-binding protein P-like, partial [Bemisia tabaci]", "id" : "XP_018910140.1" } ] },{ "sequence" : "MSEDYKLPLKQNRPSFSPPPKLRKNVITSKFVSPVLNRLTPNKTSFPYPSFNPEVGETLIEQCFKIISKIGEGSYGNVFKVQRNSDKCIFAAKVTKAPFLNEQDRNKKLNEVRLHFLFSNHNNVVTLHDAWEERGYLYLLMEFCKETLSNRSNRDHAIPETIVWKMLHDILQALSYIHSKEVIHMDVKMANIMIGQDDDFKLIDFGISNFAGEVNFQNMCGGDQRYLAPEIINQHCTKAADIFSLGVVALEMAGDFILPHEMELLAKLRKGLLPSNHNISPELSRIIQSMLTPDHTIRPSALELLKNETLIKEVRKYHLESCKRKIHGIKDCYSKYIAALACRLLSILNFGLKFFTNVLFSRQRIPVIVEPKTPDCTPEEVGSVSNVISATPPGLTSSGIKDRSSKQLASAISTRRLALTKMTSLKTASSPARNLKHEFSSDDED", "md5" : "3cc5e28ae6d3ba8a898eaa06aed60b1f", "matches" : [ { "signature" : { "accession" : "G3DSA:1.10.510.10", "name" : "Transferase(Phosphotransferase) domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 142, "end" : 313, "hmmStart" : 9, "hmmEnd" : 171, "hmmLength" : 175, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-42, "score" : 146.5, "envelopeStart" : 142, "envelopeEnd" : 313, "postProcessed" : true, "location-fragments" : [ { "start" : 142, "end" : 313, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-42, "score" : 147.0, "model-ac" : "3p1aA02" }, { "signature" : { "accession" : "PTHR11042:SF99", "name" : "MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 395, "hmmStart" : 169, "hmmEnd" : 454, "hmmLength" : 523, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 443, "location-fragments" : [ { "start" : 18, "end" : 395, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-76, "familyName" : "MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE", "score" : 260.2, "model-ac" : "PTHR11042:SF99" }, { "signature" : { "accession" : "G3DSA:3.30.200.20", "name" : "Phosphorylase Kinase; domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 36, "end" : 140, "hmmStart" : 16, "hmmEnd" : 110, "hmmLength" : 112, "hmmBounds" : "COMPLETE", "evalue" : 8.9E-28, "score" : 98.7, "envelopeStart" : 36, "envelopeEnd" : 140, "postProcessed" : true, "location-fragments" : [ { "start" : 36, "end" : 140, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-28, "score" : 99.6, "model-ac" : "3p1aA01" }, { "signature" : { "accession" : "PTHR11042", "name" : "EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 395, "hmmStart" : 169, "hmmEnd" : 454, "hmmLength" : 523, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 443, "location-fragments" : [ { "start" : 18, "end" : 395, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-76, "familyName" : "MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE", "score" : 260.2, "model-ac" : "PTHR11042" }, { "signature" : { "accession" : "PF00069", "name" : "Pkinase", "description" : "Protein kinase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 65, "end" : 308, "hmmStart" : 2, "hmmEnd" : 262, "hmmLength" : 264, "hmmBounds" : "INCOMPLETE", "evalue" : 9.1E-55, "score" : 185.9, "envelopeStart" : 64, "envelopeEnd" : 310, "postProcessed" : true, "location-fragments" : [ { "start" : 65, "end" : 308, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-55, "score" : 186.3, "model-ac" : "PF00069" }, { "signature" : { "accession" : "PS00108", "name" : "PROTEIN_KINASE_ST", "description" : "Serine/Threonine protein kinases active-site signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR008271", "name" : "Ser/Thr_kinase_AS", "description" : "Serine/threonine-protein kinase, active site", "type" : "ACTIVE_SITE", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 182, "end" : 194, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I3M2I4M", "alignment" : "ViHmDVKmaNIMI", "location-fragments" : [ { "start" : 182, "end" : 194, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00108" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 54, "end" : 323, "hmmLength" : 346, "location-fragments" : [ { "start" : 54, "end" : 323, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.65E-65, "model-ac" : "0046180" }, { "signature" : { "accession" : "SM00220", "name" : "serkin_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 64, "end" : 310, "hmmStart" : 1, "hmmEnd" : 231, "hmmLength" : 231, "hmmBounds" : "COMPLETE", "evalue" : 7.9E-52, "score" : 188.2, "location-fragments" : [ { "start" : 64, "end" : 310, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-52, "score" : 188.2, "model-ac" : "SM00220" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 20, "location-fragments" : [ { "start" : 1, "end" : 20, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS00107", "name" : "PROTEIN_KINASE_ATP", "description" : "Protein kinases ATP-binding region signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017441", "name" : "Protein_kinase_ATP_BS", "description" : "Protein kinase, ATP binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 70, "end" : 93, "level" : "STRONG", "cigarAlignment" : "10M1I1M8I4M", "alignment" : "IGEGSYGNVFkVqrnsdkciFAAK", "location-fragments" : [ { "start" : 70, "end" : 93, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00107" }, { "signature" : { "accession" : "PS50011", "name" : "PROTEIN_KINASE_DOM", "description" : "Protein kinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 64, "end" : 310, "score" : 38.365, "alignment" : "FKIISKIGEGSYGNVFKVQRNSDKCIFAAKVTKAPFLNEQDRNKKLNEVRLHFLFsNHNNVVTLHDAWEERGYLYLLMEFCKE-TLSNRSNRD--HaIPETIVWKMLHDILQALSYIHSKEVIHMDVKMANIMIGQDDDFKLIDFGISNFA--GEVnFQNMCGGDQRYLAPEII--NQHCTKAADIFSLGVVALEMA-GDFIL---PHEMELLAKLRKGLL----PSNHNISPELSRIIQSMLTPDHTIRPSALELLKNETL", "location-fragments" : [ { "start" : 64, "end" : 310, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50011" } ], "xref" : [ { "name" : "XP_018910449.1 PREDICTED: membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [Bemisia tabaci]", "id" : "XP_018910449.1" } ] },{ "sequence" : "MLIIDQTFQNSAMGGDQTCYSECRKLVENLVNDISSGLDGIETEVLPKISLLKKSIGVLIDQSVSVSRAHIYKDFLSEFADVDIKTRVQTKIFNALEEEISKLKLLVNDQDMKLMKCRSAMVPLETFTLSLKESHVNLLNAVEMTKDCSQIFTYLCIKLQIATACIKYEDISSLNKLTNFPNDIRNAKKTILEKKKAIADLLLLPMNEEEIKLVTVGN", "md5" : "8ad8a11f69db5fbc36373d7708d8386d", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 93, "end" : 113, "location-fragments" : [ { "start" : 93, "end" : 113, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" } ], "xref" : [ { "name" : "XP_018909752.1 PREDICTED: uncharacterized protein LOC109038933 isoform X1 [Bemisia tabaci]", "id" : "XP_018909752.1" } ] },{ "sequence" : "MADIELNIDNLIQRLLEVRGCRPGKSVQMSEAEVRGLCSKSREIFLQQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQGMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGIDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYAGMNSGRPSTPQRNPIKKK", "md5" : "cfe8d6a8e0d9c0cf0b7e077b4cba4320", "matches" : [ { "signature" : { "accession" : "PTHR11668:SF414", "name" : "SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-BETA CATALYTIC SUBUNIT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 320, "hmmStart" : 1, "hmmEnd" : 320, "hmmLength" : 327, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 325, "location-fragments" : [ { "start" : 1, "end" : 320, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.2E-220, "familyName" : "SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-BETA CATALYTIC SUBUNIT", "score" : 731.3, "model-ac" : "PTHR11668:SF414" }, { "signature" : { "accession" : "cd07414", "name" : "MPP_PP1_PPKL", "description" : "MPP_PP1_PPKL", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 297, "sites" : [ { "description" : "natural toxin binding site", "numLocations" : 16, "siteLocations" : [ { "start" : 271, "end" : 271, "residue" : "Y" }, { "start" : 273, "end" : 273, "residue" : "G" }, { "start" : 196, "end" : 196, "residue" : "D" }, { "start" : 133, "end" : 133, "residue" : "Y" }, { "start" : 205, "end" : 205, "residue" : "W" }, { "start" : 95, "end" : 95, "residue" : "R" }, { "start" : 275, "end" : 275, "residue" : "F" }, { "start" : 129, "end" : 129, "residue" : "I" }, { "start" : 272, "end" : 272, "residue" : "C" }, { "start" : 219, "end" : 219, "residue" : "D" }, { "start" : 195, "end" : 195, "residue" : "P" }, { "start" : 194, "end" : 194, "residue" : "V" }, { "start" : 220, "end" : 220, "residue" : "R" }, { "start" : 221, "end" : 221, "residue" : "G" }, { "start" : 274, "end" : 274, "residue" : "E" }, { "start" : 128, "end" : 128, "residue" : "S" } ] }, { "description" : "active site", "numLocations" : 23, "siteLocations" : [ { "start" : 271, "end" : 271, "residue" : "Y" }, { "start" : 273, "end" : 273, "residue" : "G" }, { "start" : 123, "end" : 123, "residue" : "N" }, { "start" : 196, "end" : 196, "residue" : "D" }, { "start" : 133, "end" : 133, "residue" : "Y" }, { "start" : 205, "end" : 205, "residue" : "W" }, { "start" : 95, "end" : 95, "residue" : "R" }, { "start" : 275, "end" : 275, "residue" : "F" }, { "start" : 129, "end" : 129, "residue" : "I" }, { "start" : 272, "end" : 272, "residue" : "C" }, { "start" : 124, "end" : 124, "residue" : "H" }, { "start" : 172, "end" : 172, "residue" : "H" }, { "start" : 65, "end" : 65, "residue" : "H" }, { "start" : 91, "end" : 91, "residue" : "D" }, { "start" : 219, "end" : 219, "residue" : "D" }, { "start" : 195, "end" : 195, "residue" : "P" }, { "start" : 247, "end" : 247, "residue" : "H" }, { "start" : 194, "end" : 194, "residue" : "V" }, { "start" : 220, "end" : 220, "residue" : "R" }, { "start" : 63, "end" : 63, "residue" : "D" }, { "start" : 221, "end" : 221, "residue" : "G" }, { "start" : 274, "end" : 274, "residue" : "E" }, { "start" : 128, "end" : 128, "residue" : "S" } ] }, { "description" : "metal binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 172, "end" : 172, "residue" : "H" }, { "start" : 65, "end" : 65, "residue" : "H" }, { "start" : 91, "end" : 91, "residue" : "D" }, { "start" : 123, "end" : 123, "residue" : "N" }, { "start" : 247, "end" : 247, "residue" : "H" }, { "start" : 63, "end" : 63, "residue" : "D" } ] }, { "description" : "MYPT1 binding site", "numLocations" : 21, "siteLocations" : [ { "start" : 240, "end" : 240, "residue" : "L" }, { "start" : 288, "end" : 288, "residue" : "L" }, { "start" : 292, "end" : 292, "residue" : "F" }, { "start" : 178, "end" : 178, "residue" : "D" }, { "start" : 260, "end" : 260, "residue" : "R" }, { "start" : 287, "end" : 287, "residue" : "T" }, { "start" : 197, "end" : 197, "residue" : "T" }, { "start" : 294, "end" : 294, "residue" : "I" }, { "start" : 232, "end" : 232, "residue" : "A" }, { "start" : 215, "end" : 215, "residue" : "W" }, { "start" : 241, "end" : 241, "residue" : "D" }, { "start" : 180, "end" : 180, "residue" : "Q" }, { "start" : 202, "end" : 202, "residue" : "D" }, { "start" : 290, "end" : 290, "residue" : "C" }, { "start" : 235, "end" : 235, "residue" : "L" }, { "start" : 239, "end" : 239, "residue" : "D" }, { "start" : 236, "end" : 236, "residue" : "N" }, { "start" : 224, "end" : 224, "residue" : "F" }, { "start" : 256, "end" : 256, "residue" : "F" }, { "start" : 233, "end" : 233, "residue" : "K" }, { "start" : 237, "end" : 237, "residue" : "R" } ] } ], "evalue" : 0.0, "score" : 667.891, "location-fragments" : [ { "start" : 7, "end" : 297, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd07414" }, { "signature" : { "accession" : "SM00156", "name" : "pp2a_7", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006186", "name" : "Ser/Thr-sp_prot-phosphatase", "description" : "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase", "type" : "DOMAIN", "goXRefs" : [ { "name" : "hydrolase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016787" } ], "pathwayXRefs" : [ { "name" : "PD-L1 expression and PD-1 checkpoint pathway in cancer", "databaseName" : "KEGG", "id" : "05235+3.1.3.16" }, { "name" : "T cell receptor signaling pathway", "databaseName" : "KEGG", "id" : "04660+3.1.3.16" }, { "name" : "Th1 and Th2 cell differentiation", "databaseName" : "KEGG", "id" : "04658+3.1.3.16" } ] } }, "locations" : [ { "start" : 29, "end" : 299, "hmmStart" : 1, "hmmEnd" : 321, "hmmLength" : 321, "hmmBounds" : "COMPLETE", "evalue" : 7.5E-163, "score" : 557.0, "location-fragments" : [ { "start" : 29, "end" : 299, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.5E-163, "score" : 557.0, "model-ac" : "SM00156" }, { "signature" : { "accession" : "SSF56300", "name" : "Metallo-dependent phosphatases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 302, "hmmLength" : 473, "location-fragments" : [ { "start" : 24, "end" : 302, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.73E-117, "model-ac" : "0045823" }, { "signature" : { "accession" : "PF16891", "name" : "STPPase_N", "description" : "Serine-threonine protein phosphatase N-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR031675", "name" : "STPPase_N", "description" : "Serine-threonine protein phosphatase, N-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "T cell receptor signaling pathway", "databaseName" : "KEGG", "id" : "04660+3.1.3.16" }, { "name" : "PD-L1 expression and PD-1 checkpoint pathway in cancer", "databaseName" : "KEGG", "id" : "05235+3.1.3.16" }, { "name" : "Triglyceride catabolism", "databaseName" : "Reactome", "id" : "R-HSA-163560" }, { "name" : "Downregulation of TGF-beta receptor signaling", "databaseName" : "Reactome", "id" : "R-HSA-2173788" }, { "name" : "Circadian Clock", "databaseName" : "Reactome", "id" : "R-HSA-400253" }, { "name" : "Th1 and Th2 cell differentiation", "databaseName" : "KEGG", "id" : "04658+3.1.3.16" } ] } }, "locations" : [ { "start" : 8, "end" : 55, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-20, "score" : 73.6, "envelopeStart" : 8, "envelopeEnd" : 55, "postProcessed" : true, "location-fragments" : [ { "start" : 8, "end" : 55, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.3E-21, "score" : 74.0, "model-ac" : "PF16891" }, { "signature" : { "accession" : "PF00149", "name" : "Metallophos", "description" : "Calcineurin-like phosphoesterase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004843", "name" : "Calcineurin-like_PHP_ApaH", "description" : "Calcineurin-like phosphoesterase domain, ApaH type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "hydrolase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016787" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 59, "end" : 249, "hmmStart" : 4, "hmmEnd" : 203, "hmmLength" : 205, "hmmBounds" : "INCOMPLETE", "evalue" : 9.7E-39, "score" : 134.0, "envelopeStart" : 56, "envelopeEnd" : 251, "postProcessed" : true, "location-fragments" : [ { "start" : 59, "end" : 249, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.8E-39, "score" : 134.3, "model-ac" : "PF00149" }, { "signature" : { "accession" : "G3DSA:3.60.21.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029052", "name" : "Metallo-depent_PP-like", "description" : "Metallo-dependent phosphatase-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 308, "hmmStart" : 7, "hmmEnd" : 311, "hmmLength" : 311, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-141, "score" : 472.7, "envelopeStart" : 1, "envelopeEnd" : 308, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 308, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-141, "score" : 472.9, "model-ac" : "1s70A00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 305, "end" : 325, "location-fragments" : [ { "start" : 305, "end" : 325, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR11668", "name" : "SERINE/THREONINE PROTEIN PHOSPHATASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 320, "hmmStart" : 1, "hmmEnd" : 320, "hmmLength" : 327, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 325, "location-fragments" : [ { "start" : 1, "end" : 320, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.2E-220, "familyName" : "SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-BETA CATALYTIC SUBUNIT", "score" : 731.3, "model-ac" : "PTHR11668" }, { "signature" : { "accession" : "PS00125", "name" : "SER_THR_PHOSPHATASE", "description" : "Serine/threonine specific protein phosphatases signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR006186", "name" : "Ser/Thr-sp_prot-phosphatase", "description" : "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase", "type" : "DOMAIN", "goXRefs" : [ { "name" : "hydrolase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016787" } ], "pathwayXRefs" : [ { "name" : "PD-L1 expression and PD-1 checkpoint pathway in cancer", "databaseName" : "KEGG", "id" : "05235+3.1.3.16" }, { "name" : "T cell receptor signaling pathway", "databaseName" : "KEGG", "id" : "04660+3.1.3.16" }, { "name" : "Th1 and Th2 cell differentiation", "databaseName" : "KEGG", "id" : "04658+3.1.3.16" } ] } }, "locations" : [ { "start" : 120, "end" : 125, "level" : "STRONG", "cigarAlignment" : "6M", "alignment" : "LRGNHE", "location-fragments" : [ { "start" : 120, "end" : 125, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00125" }, { "signature" : { "accession" : "PR00114", "name" : "STPHPHTASE", "description" : "Serine/threonine phosphatase family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR006186", "name" : "Ser/Thr-sp_prot-phosphatase", "description" : "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase", "type" : "DOMAIN", "goXRefs" : [ { "name" : "hydrolase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016787" } ], "pathwayXRefs" : [ { "name" : "PD-L1 expression and PD-1 checkpoint pathway in cancer", "databaseName" : "KEGG", "id" : "05235+3.1.3.16" }, { "name" : "T cell receptor signaling pathway", "databaseName" : "KEGG", "id" : "04660+3.1.3.16" }, { "name" : "Th1 and Th2 cell differentiation", "databaseName" : "KEGG", "id" : "04658+3.1.3.16" } ] } }, "locations" : [ { "start" : 182, "end" : 209, "pvalue" : 3.33E-15, "score" : 58.33, "motifNumber" : 5, "location-fragments" : [ { "start" : 182, "end" : 209, "dc-status" : "CONTINUOUS" } ] }, { "start" : 239, "end" : 259, "pvalue" : 3.92E-13, "score" : 61.61, "motifNumber" : 6, "location-fragments" : [ { "start" : 239, "end" : 259, "dc-status" : "CONTINUOUS" } ] }, { "start" : 261, "end" : 277, "pvalue" : 2.72E-11, "score" : 69.93, "motifNumber" : 7, "location-fragments" : [ { "start" : 261, "end" : 277, "dc-status" : "CONTINUOUS" } ] }, { "start" : 57, "end" : 84, "pvalue" : 1.0E-16, "score" : 64.53, "motifNumber" : 1, "location-fragments" : [ { "start" : 57, "end" : 84, "dc-status" : "CONTINUOUS" } ] }, { "start" : 153, "end" : 179, "pvalue" : 1.0E-16, "score" : 61.27, "motifNumber" : 4, "location-fragments" : [ { "start" : 153, "end" : 179, "dc-status" : "CONTINUOUS" } ] }, { "start" : 119, "end" : 143, "pvalue" : 2.22E-16, "score" : 69.68, "motifNumber" : 3, "location-fragments" : [ { "start" : 119, "end" : 143, "dc-status" : "CONTINUOUS" } ] }, { "start" : 86, "end" : 113, "pvalue" : 1.0E-16, "score" : 73.97, "motifNumber" : 2, "location-fragments" : [ { "start" : 86, "end" : 113, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-96, "graphscan" : "IIIIIII", "model-ac" : "PR00114" } ], "xref" : [ { "name" : "XP_018909856.1 PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit [Bemisia tabaci]", "id" : "XP_018909856.1" } ] },{ "sequence" : "MTLKVVICVAALLIDLQGTWSDEASSAAKIGSMQSNIKGLLQKADKEIEEEVRDIMSRILFIRDQEVAEKKTKLATDMKPVTESLRELLERTRADEPENGCLAEFDPNYAQAVTNAGYEHFRGCVANYPPGGSVNMDITELRQSFRDLERNTSDALNDCKQGPEVHAEICLESLNEAFRADLARLKESRMTHMKSEAAEAEILERVKMEECMKEALTNARVMKDTFKDVIHNCVTQPRQIDPRINLALPRE", "md5" : "25d13def7d5aa3f9e1e4c7bac7587aa9", "matches" : [ ], "xref" : [ { "name" : "XP_018910239.1 PREDICTED: uncharacterized protein LOC109039257 [Bemisia tabaci]", "id" : "XP_018910239.1" } ] },{ "sequence" : "MSDAQAQAAEYESSLGDLTVNSKPLINVLTMLAEENIAIAPLIVKAIENHIQTVSGDVKLPALYLVDSILKNVGKDYTNLFLRNLVSMFCGAFEKVDEKTRSQMFKLRSTWTNVLPPMILYELDTKVCTIDPAWPVGPPPPIPHIASSNNRIHLNPKFLNATTPSPSAAPSKKSIFSPTPIGTPSVAKTPEQTMSAEELKIQKKKLAELEELNKFLDSNIKAGQQQIKSKQQVASYPVGITNIEQLEKLVATCEAELGALILKCSELSKSPKNMDALKEAMLKKKLLTDMLKTLKRKQPVSSAPLTTVTSSKPVVASTAVAPHASSSLATDLSSSSPKSLAVPVPSKLAASSGHRQETMNVDEVTSISCDSTSLSKQSPRAKSVAAPSQAPRVAISPASSLLINAAQRVRDPRLRKLKDSKSGGTSPPVSSPVSSPAESNCAINNGAPSSPRKGVVDAAKEEADALKPEKSTERSKDKEKRRKSKKSSKTDTHPSSPKGSPKTDKLESEESASTDLKKSCSDELIQKAMSSPVVAPALLKTEMILKPPQDVDLRVLPTSPKKRVSDNKSEEPPTKKNKAEMYNMLFGNEDVDLRQDVDLRLPVTGVPLLVSSISAPTQHLATAAVFDSSMTMSTASSPKAVAPVTIAQRPETSKTSKPSSSSTSSPKRESAKESSRPSSSKSKAESKKSSEKSASSRRAKKSPSPPLSKTPSPPPPPIISMKRDSPLKESTKENSRSWAKYKEVKPDKFKSPYRIPTKRFNPRLERPIEPNKLDHIIQHQSPLSYRSELDAGKETRSYLDNQHLNMNTYRSSYYTDMNHSNDISSIGERRPKTMADMKAEPLDEGSRAPEPYQPELRMSEPVSVKMEQCLEPYTSPKMETEPGSEVPVVLPEPPKPPATLLPPLPQPPQPLPMPQHYPAPLLQPPIVPVRPMVHPQGPLRHDLVDHPERSRMMLDHPERPRMMNHQERPRMMLDHQERHPFPRPNFNFNHHPGMRPSHLFVGPGRPPLRLSCDFAPTNPKLLEICALDVMTTINIDGVPREIRFYGLTAVVFLSNDDPREIRFQEGYRNVLFNDEDSIRLKLNDEAVDFELDGKIHKIRLGAPTRELYIDGKGFSLGWNTEPTPIFIDGKEHHVQLEGEPPPVTILPEKRLDLVAGKINLVVDGEQLITMYLDYKPQRFDIDGVPYVLQFMNALKRVKINNRVFNTDFGGKPKPFVFHGIRHFLRLSALPKGIVPGEVKLYGMEDVVSPPVPPAGSHPPLRQEDGAPHPSSDHIGDRPDHRRMSSRHRSKLGPQDKHFAVESRNERRPRHEVDKHSNSGASDGFSGSHSTSHSKSNQDNENSNESSTSSKTTSFLGELPSYSVTELVQKLFAKGMLGKAVEEKKEETPKAVDSELKQVDFTKPETLKVRQPAMITKLYSGQQCSTCGLRFLDGLTDKYSQHLDWHYRQNRRKKDMAHTVQSRQWYYDISDWIQFEEIEILEERAQSWFESQVIDEEGREIPGELVSVPAGSDLAEGVCVHCHDPFELFYHAEAEEWHFRHAICVDKKLYHPVCHQDWLLSLEVEAENARKELEELETKKLEEEKKKEEEKRIEEEKKKEEEIKKEEELKMEEEKGKESVSVKTEVTESDSEMTGNDAVKSETEVKIESNSGSGAVEELVVTIKEEPMEISVEEGDSSKMKTDVDSEATAEQPKEEILEKMETEDSDLQTEVVIANIEIKKEDTDLNVVADSQVDTTYAGVTSSIDGNVELKESSQETVRSSGKIKINISKPVLSPAIPEEPVEPEPMAEESEPIGEPASGVTIDPNEPFPPGLEPTEPVVKLKPRLVGRKLTEYPPISKGTELSGLCSIM", "md5" : "dbe097e074e61e3d5395a6e058865d41", "matches" : [ { "signature" : { "accession" : "PS51391", "name" : "CID", "description" : "CID domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR006569", "name" : "CID_dom", "description" : "CID domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3, "end" : 131, "score" : 35.39, "alignment" : "DAQAQAAEYESSLGDLTvNSKPLINVLTMLAEENIAIAPLIVKAIENHIQTVSGDV-KLPALYLVDSILKNV-----GKDYTNLFLRNLVSMFCGAFEKVDEKT-RSQMFKLRSTWT--NVLPPMILYELDTKVCTID", "location-fragments" : [ { "start" : 3, "end" : 131, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51391" }, { "signature" : { "accession" : "PTHR15921", "name" : "PRE-MRNA CLEAVAGE COMPLEX II", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 1698, "hmmStart" : 1, "hmmEnd" : 1052, "hmmLength" : 1099, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 1808, "location-fragments" : [ { "start" : 1, "end" : 1698, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-137, "familyName" : "PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11", "score" : 462.9, "model-ac" : "PTHR15921" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 455, "end" : 478, "location-fragments" : [ { "start" : 455, "end" : 478, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.25.40.90", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR008942", "name" : "ENTH_VHS", "description" : "ENTH/VHS", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 128, "hmmStart" : 10, "hmmEnd" : 138, "hmmLength" : 143, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-39, "score" : 137.0, "envelopeStart" : 1, "envelopeEnd" : 128, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 128, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-40, "score" : 138.0, "model-ac" : "2bf0X00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 345, "end" : 365, "location-fragments" : [ { "start" : 345, "end" : 365, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 351, "end" : 365, "location-fragments" : [ { "start" : 351, "end" : 365, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 648, "end" : 668, "location-fragments" : [ { "start" : 648, "end" : 668, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 640, "end" : 739, "location-fragments" : [ { "start" : 640, "end" : 739, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 557, "end" : 577, "location-fragments" : [ { "start" : 557, "end" : 577, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 370, "end" : 384, "location-fragments" : [ { "start" : 370, "end" : 384, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 423, "end" : 447, "location-fragments" : [ { "start" : 423, "end" : 447, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 370, "end" : 389, "location-fragments" : [ { "start" : 370, "end" : 389, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00582", "name" : "558neu5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006569", "name" : "CID_dom", "description" : "CID domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 128, "hmmStart" : 1, "hmmEnd" : 146, "hmmLength" : 146, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-27, "score" : 107.8, "location-fragments" : [ { "start" : 6, "end" : 128, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-27, "score" : 107.8, "model-ac" : "SM00582" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 706, "end" : 721, "location-fragments" : [ { "start" : 706, "end" : 721, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 277, "end" : 297, "location-fragments" : [ { "start" : 277, "end" : 297, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 669, "end" : 698, "location-fragments" : [ { "start" : 669, "end" : 698, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR15921:SF3", "name" : "PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 1698, "hmmStart" : 1, "hmmEnd" : 1052, "hmmLength" : 1099, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 1808, "location-fragments" : [ { "start" : 1, "end" : 1698, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-137, "familyName" : "PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11", "score" : 462.9, "model-ac" : "PTHR15921:SF3" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 498, "end" : 518, "location-fragments" : [ { "start" : 498, "end" : 518, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1661, "end" : 1704, "location-fragments" : [ { "start" : 1661, "end" : 1704, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 199, "end" : 226, "location-fragments" : [ { "start" : 199, "end" : 226, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF04818", "name" : "CID", "description" : "CID domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006569", "name" : "CID_dom", "description" : "CID domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 20, "end" : 112, "hmmStart" : 11, "hmmEnd" : 110, "hmmLength" : 123, "hmmBounds" : "INCOMPLETE", "evalue" : 1.2E-11, "score" : 44.8, "envelopeStart" : 9, "envelopeEnd" : 123, "postProcessed" : true, "location-fragments" : [ { "start" : 20, "end" : 112, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-12, "score" : 46.7, "model-ac" : "PF04818" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 243, "end" : 263, "location-fragments" : [ { "start" : 243, "end" : 263, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1249, "end" : 1351, "location-fragments" : [ { "start" : 1249, "end" : 1351, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1266, "end" : 1317, "location-fragments" : [ { "start" : 1266, "end" : 1317, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 725, "end" : 739, "location-fragments" : [ { "start" : 725, "end" : 739, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1656, "end" : 1704, "location-fragments" : [ { "start" : 1656, "end" : 1704, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 406, "end" : 518, "location-fragments" : [ { "start" : 406, "end" : 518, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF48464", "name" : "ENTH/VHS domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR008942", "name" : "ENTH_VHS", "description" : "ENTH/VHS", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3, "end" : 141, "hmmLength" : 144, "location-fragments" : [ { "start" : 3, "end" : 141, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.01E-39, "model-ac" : "0049499" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1558, "end" : 1616, "location-fragments" : [ { "start" : 1558, "end" : 1616, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1318, "end" : 1351, "location-fragments" : [ { "start" : 1318, "end" : 1351, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd16982", "name" : "CID_Pcf11", "description" : "CID_Pcf11", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 131, "sites" : [ { "description" : "CTD binding site", "numLocations" : 11, "siteLocations" : [ { "start" : 24, "end" : 24, "residue" : "P" }, { "start" : 67, "end" : 67, "residue" : "D" }, { "start" : 23, "end" : 23, "residue" : "K" }, { "start" : 71, "end" : 71, "residue" : "K" }, { "start" : 110, "end" : 110, "residue" : "T" }, { "start" : 68, "end" : 68, "residue" : "S" }, { "start" : 72, "end" : 72, "residue" : "N" }, { "start" : 26, "end" : 26, "residue" : "I" }, { "start" : 64, "end" : 64, "residue" : "Y" }, { "start" : 103, "end" : 103, "residue" : "Q" }, { "start" : 107, "end" : 107, "residue" : "L" } ] } ], "evalue" : 1.30779E-56, "score" : 190.084, "location-fragments" : [ { "start" : 8, "end" : 131, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd16982" }, { "signature" : { "accession" : "PF11526", "name" : "CFIA_Pcf11", "description" : "Subunit of cleavage factor IA Pcf11", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR021605", "name" : "CFIA_Pcf11", "description" : "Subunit of cleavage factor IA Pcf11", "type" : "FAMILY", "goXRefs" : [ { "name" : "termination of RNA polymerase II transcription", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006369" }, { "name" : "mRNA cleavage", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006379" }, { "name" : "mRNA cleavage factor complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005849" }, { "name" : "mRNA polyadenylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006378" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1451, "end" : 1484, "hmmStart" : 3, "hmmEnd" : 36, "hmmLength" : 90, "hmmBounds" : "INCOMPLETE", "evalue" : 7.5E-5, "score" : 23.1, "envelopeStart" : 1449, "envelopeEnd" : 1496, "postProcessed" : true, "location-fragments" : [ { "start" : 1451, "end" : 1484, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.5E-5, "score" : 23.1, "model-ac" : "PF11526" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1775, "end" : 1817, "location-fragments" : [ { "start" : 1775, "end" : 1817, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909607.1 PREDICTED: uncharacterized protein LOC109038843 isoform X2 [Bemisia tabaci]", "id" : "XP_018909607.1" } ] },{ "sequence" : "MWELARRALLGALTLCLLSNVVDLSIPATPKNAAKSATPCKLSEFYCDTGQCLPLDKFCNGADDCGDKSDEPKYCTPCNRTYYGQVGRTYELEIRRPREDRLPLLCFLNFTAAGGSLGDLVQLTFDAFTVGRFVSFTMDGCPDGYMTIREEGRPDTKGQWCGSAWGYTVYYSETRSLNLSLNLFTLSDQGISGYNFDFKLSYKFLKYNEAHLRYGNSSQLSYRGELVQGSYCTRQLNKCDTRPCRVQSPNFPGIYPRNVTCYYRLEHNKVPSGKQALIAVRQRNSHKIHIKDQMVKYERSQRLLRVWDECNVVQDYLTVYDGGSTMDPVLVRLCGGDAVPDIISSGPDMLLEFHTSPYDNPFHPVPLSYLPGFELDVQIMYVEARSGSSSSPGGVSSVGGAGGGQRSRAGDGGRSRLKCLFTVSSFDSSWGLVENPRHSLPPNTTCFYQFQGRKDETVWLSFIKYHAASAGTIQSGAYHDAECNARLRIWDGRLPSEAQPQTNSTLIHEFCKEDAPKLCDHYFLSNTTRMTRPCSLSESYISRSQDLTLELFLRQGSVLYPINFLLRYEFVNTALEGARYNESGNQCDRLFKSEKSPLGSFRSPKSVFFYGRGGRRNVTCIFRFEPRWDEQVRIKLTRVKFGNRLCSTVFDSRIPGKQVCSREFHTFGFFNSPHNSTEGVSELWINEYPWAEEIKLPRHCVCSELDKVLTFTSLISSVIELNFTILNMNITEDYNDYFFEGEFNFVHIADADSVRKCELLKLDRRLSGTSGEITLPRKPEVVDHNSEVKITQIRLPEHLLCNNYPYLIQSSDSYLYLRVRGYELGYQSLLHWQDKLYQTQCSTKNRVVVYSVADSRDFKVVCPQDTSRYTSFDEDVQLFSKGWHDAFNQDYTILKPLERNFVVEFIGDEQETESYSIFWMQVSKRPDLAPAVSSRLSSEHTILDCPYRCPELNACISWTLWCDGKPHCPGGFDEEESNCAFQFGVSFLYITIGSSCLFILSVLLLLTLCIRSRSKEKYDPSERPRPPHPHPHGGHNHLHLNQNGDSAKHIHQLQTQLPSTDDLFIGVKDIC", "md5" : "10c993f9e373878b1cc9ad5b5d8882f5", "matches" : [ { "signature" : { "accession" : "PS01180", "name" : "CUB", "description" : "CUB domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000859", "name" : "CUB_dom", "description" : "CUB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 78, "end" : 205, "score" : 8.886, "alignment" : "CNRTYYGQVGRTYELEIRR---PREdrlpLLCFLNFTAAGGsLGDLVQLTFDA-FTVGRFVSftmdgCPDGYMTIREEgrpDTKGQWCGSAWGYTVyyseTRSLNLSLNLFTLSDQGISGynFDFKLSYKFL", "location-fragments" : [ { "start" : 78, "end" : 205, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01180" }, { "signature" : { "accession" : "PR00261", "name" : "LDLRECEPTOR", "description" : "Low density lipoprotein (LDL) receptor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 71, "pvalue" : 5.13E-8, "score" : 46.78, "motifNumber" : 1, "location-fragments" : [ { "start" : 50, "end" : 71, "dc-status" : "CONTINUOUS" } ] }, { "start" : 953, "end" : 974, "pvalue" : 7.06E-5, "score" : 37.69, "motifNumber" : 6, "location-fragments" : [ { "start" : 953, "end" : 974, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.9E-6, "graphscan" : "I....I", "model-ac" : "PR00261" }, { "signature" : { "accession" : "PS01180", "name" : "CUB", "description" : "CUB domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000859", "name" : "CUB_dom", "description" : "CUB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 232, "end" : 380, "score" : 12.855, "alignment" : "CTRQLNKCdtrPCRVQSPNFPGI-YPRNVTCYYRLEHNKVpsgkqaliavrqrNSHKIHIKDQM-VKYERSQRllrvwdecnVVQDYLTVYDGgstmdPVLVRLCGGDAVPDIISS-GPDMLLEFHTspyDNPFHPvplsylPGFELDVQIM", "location-fragments" : [ { "start" : 232, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01180" }, { "signature" : { "accession" : "cd00112", "name" : "LDLa", "description" : "LDLa", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 40, "end" : 71, "sites" : [ { "description" : "putative binding surface", "numLocations" : 4, "siteLocations" : [ { "start" : 53, "end" : 53, "residue" : "L" }, { "start" : 65, "end" : 65, "residue" : "C" }, { "start" : 45, "end" : 45, "residue" : "F" }, { "start" : 64, "end" : 64, "residue" : "D" } ] }, { "description" : "D-X-S-D-E motif", "numLocations" : 5, "siteLocations" : [ { "start" : 70, "end" : 70, "residue" : "D" }, { "start" : 67, "end" : 67, "residue" : "D" }, { "start" : 71, "end" : 71, "residue" : "E" }, { "start" : 69, "end" : 69, "residue" : "S" }, { "start" : 68, "end" : 68, "residue" : "K" } ] }, { "description" : "calcium-binding site", "numLocations" : 5, "siteLocations" : [ { "start" : 70, "end" : 70, "residue" : "D" }, { "start" : 71, "end" : 71, "residue" : "E" }, { "start" : 64, "end" : 64, "residue" : "D" }, { "start" : 60, "end" : 60, "residue" : "N" }, { "start" : 57, "end" : 57, "residue" : "K" } ] } ], "evalue" : 1.8161E-9, "score" : 51.8238, "location-fragments" : [ { "start" : 40, "end" : 71, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00112" }, { "signature" : { "accession" : "cd00041", "name" : "CUB", "description" : "CUB", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000859", "name" : "CUB_dom", "description" : "CUB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 245, "end" : 360, "sites" : [ ], "evalue" : 4.00073E-16, "score" : 73.2154, "location-fragments" : [ { "start" : 245, "end" : 360, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00041" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1017, "end" : 1041, "location-fragments" : [ { "start" : 1017, "end" : 1041, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF49854", "name" : "Spermadhesin, CUB domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035914", "name" : "Sperma_CUB_dom_sf", "description" : "Spermadhesin, CUB domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 246, "end" : 359, "hmmLength" : 108, "location-fragments" : [ { "start" : 246, "end" : 359, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.97E-15, "model-ac" : "0054622" }, { "signature" : { "accession" : "SM00042", "name" : "CUB_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000859", "name" : "CUB_dom", "description" : "CUB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 232, "end" : 380, "hmmStart" : 1, "hmmEnd" : 144, "hmmLength" : 144, "hmmBounds" : "COMPLETE", "evalue" : 9.2E-4, "score" : 24.8, "location-fragments" : [ { "start" : 232, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.2E-4, "score" : 24.8, "model-ac" : "SM00042" }, { "signature" : { "accession" : "PS01209", "name" : "LDLRA_1", "description" : "LDL-receptor class A (LDLRA) domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR023415", "name" : "LDLR_class-A_CS", "description" : "Low-density lipoprotein (LDL) receptor class A, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 52, "end" : 75, "level" : "STRONG", "cigarAlignment" : "2M5I2M3I2M3I3M3I1M", "alignment" : "CLpldkfCNgadDCgdkSDEpkyC", "location-fragments" : [ { "start" : 52, "end" : 75, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01209" }, { "signature" : { "accession" : "PF00431", "name" : "CUB", "description" : "CUB domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000859", "name" : "CUB_dom", "description" : "CUB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 240, "end" : 356, "hmmStart" : 6, "hmmEnd" : 98, "hmmLength" : 110, "hmmBounds" : "INCOMPLETE", "evalue" : 1.3E-7, "score" : 32.0, "envelopeStart" : 232, "envelopeEnd" : 361, "postProcessed" : true, "location-fragments" : [ { "start" : 240, "end" : 356, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-13, "score" : 49.1, "model-ac" : "PF00431" }, { "signature" : { "accession" : "PTHR47537:SF3", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 58, "end" : 1022, "hmmStart" : 6, "hmmEnd" : 922, "hmmLength" : 949, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 31, "envelopeEnd" : 1052, "location-fragments" : [ { "start" : 58, "end" : 1022, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-262, "familyName" : "", "score" : 876.5, "model-ac" : "PTHR47537:SF3" }, { "signature" : { "accession" : "SM00192", "name" : "LDLa_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 944, "end" : 981, "hmmStart" : 1, "hmmEnd" : 47, "hmmLength" : 47, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-4, "score" : 29.4, "location-fragments" : [ { "start" : 944, "end" : 981, "dc-status" : "CONTINUOUS" } ] }, { "start" : 39, "end" : 77, "hmmStart" : 1, "hmmEnd" : 47, "hmmLength" : 47, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-11, "score" : 54.6, "location-fragments" : [ { "start" : 39, "end" : 77, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-20, "score" : 84.0, "model-ac" : "SM00192" }, { "signature" : { "accession" : "PTHR47537", "name" : "CUBILIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 58, "end" : 1022, "hmmStart" : 6, "hmmEnd" : 922, "hmmLength" : 949, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 31, "envelopeEnd" : 1052, "location-fragments" : [ { "start" : 58, "end" : 1022, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-262, "familyName" : "", "score" : 876.5, "model-ac" : "PTHR47537" }, { "signature" : { "accession" : "G3DSA:2.40.128.620", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 944, "end" : 1018, "hmmStart" : 8, "hmmEnd" : 44, "hmmLength" : 170, "hmmBounds" : "COMPLETE", "evalue" : 3.8E-6, "score" : 29.3, "envelopeStart" : 944, "envelopeEnd" : 1018, "postProcessed" : true, "location-fragments" : [ { "start" : 944, "end" : 1018, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-13, "score" : 53.3, "model-ac" : "4u8uN02" }, { "signature" : { "accession" : "PF00057", "name" : "Ldl_recept_a", "description" : "Low-density lipoprotein receptor domain class A", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 39, "end" : 75, "hmmStart" : 2, "hmmEnd" : 37, "hmmLength" : 37, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.8E-9, "score" : 36.6, "envelopeStart" : 38, "envelopeEnd" : 75, "postProcessed" : true, "location-fragments" : [ { "start" : 39, "end" : 75, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-9, "score" : 36.6, "model-ac" : "PF00057" }, { "signature" : { "accession" : "G3DSA:2.60.120.290", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR035914", "name" : "Sperma_CUB_dom_sf", "description" : "Spermadhesin, CUB domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 424, "end" : 574, "hmmStart" : 20, "hmmEnd" : 100, "hmmLength" : 124, "hmmBounds" : "COMPLETE", "evalue" : 2.6E-5, "score" : 26.5, "envelopeStart" : 424, "envelopeEnd" : 574, "postProcessed" : true, "location-fragments" : [ { "start" : 424, "end" : 574, "dc-status" : "CONTINUOUS" } ] }, { "start" : 232, "end" : 380, "hmmStart" : 9, "hmmEnd" : 108, "hmmLength" : 124, "hmmBounds" : "COMPLETE", "evalue" : 9.5E-17, "score" : 63.5, "envelopeStart" : 232, "envelopeEnd" : 380, "postProcessed" : true, "location-fragments" : [ { "start" : 232, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-31, "score" : 110.1, "model-ac" : "4gz9A02" }, { "signature" : { "accession" : "PS50068", "name" : "LDLRA_2", "description" : "LDL-receptor class A (LDLRA) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 39, "end" : 76, "score" : 12.512, "alignment" : "PCKLSEFYCDTGQCLPLDKFCNGADDCGDKSDEpKYCT", "location-fragments" : [ { "start" : 39, "end" : 76, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50068" }, { "signature" : { "accession" : "SSF57424", "name" : "LDL receptor-like module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036055", "name" : "LDL_receptor-like_sf", "description" : "LDL receptor-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 73, "hmmLength" : 47, "location-fragments" : [ { "start" : 37, "end" : 73, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-9, "model-ac" : "0039720" }, { "signature" : { "accession" : "cd00112", "name" : "LDLa", "description" : "LDLa", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 955, "end" : 979, "sites" : [ { "description" : "D-X-S-D-E motif", "numLocations" : 5, "siteLocations" : [ { "start" : 974, "end" : 974, "residue" : "E" }, { "start" : 972, "end" : 972, "residue" : "F" }, { "start" : 970, "end" : 970, "residue" : "G" }, { "start" : 971, "end" : 971, "residue" : "G" }, { "start" : 973, "end" : 973, "residue" : "D" } ] }, { "description" : "calcium-binding site", "numLocations" : 5, "siteLocations" : [ { "start" : 974, "end" : 974, "residue" : "E" }, { "start" : 963, "end" : 963, "residue" : "D" }, { "start" : 967, "end" : 967, "residue" : "H" }, { "start" : 960, "end" : 960, "residue" : "L" }, { "start" : 973, "end" : 973, "residue" : "D" } ] } ], "evalue" : 0.00482809, "score" : 33.7194, "location-fragments" : [ { "start" : 955, "end" : 979, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00112" }, { "signature" : { "accession" : "G3DSA:4.10.400.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036055", "name" : "LDL_receptor-like_sf", "description" : "LDL receptor-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 36, "end" : 71, "hmmStart" : 5, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-9, "score" : 38.9, "envelopeStart" : 36, "envelopeEnd" : 71, "postProcessed" : true, "location-fragments" : [ { "start" : 36, "end" : 71, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-12, "score" : 48.6, "model-ac" : "1xfeA01" } ], "xref" : [ { "name" : "XP_018910538.1 PREDICTED: uncharacterized protein LOC109039500 [Bemisia tabaci]", "id" : "XP_018910538.1" } ] },{ "sequence" : "MNLIHNVKCFPRKKFFQTLSAIENENIILRKHSAFSPYRTNNKYCFSSPFTKVSITYSQNYYSTGLQFCKVPRTNVSTRTRQSTRSFFESSGADINTNVSRDVVIFEYNNDRLFAIIKVFGISQIFVWGYLANTAYTCLKDAPVEKPPHRELQWWEKVNLGENWVRNGITTLCVIMGFGLSLLAHALSLRTVKQIILHRGGRDITIHTYSSFVGNRFRVPLHMVSCSVSRKGSPHHLPLKIKGKWFYFTLDSRGTYPHPTLFEWTAGLKRSL", "md5" : "31ba05048d04808fb47dfc07aff8f754", "matches" : [ { "signature" : { "accession" : "PF14640", "name" : "TMEM223", "description" : "Transmembrane protein 223", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 101, "end" : 270, "hmmStart" : 1, "hmmEnd" : 169, "hmmLength" : 169, "hmmBounds" : "COMPLETE", "evalue" : 8.2E-49, "score" : 165.9, "envelopeStart" : 101, "envelopeEnd" : 270, "postProcessed" : true, "location-fragments" : [ { "start" : 101, "end" : 270, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-49, "score" : 166.7, "model-ac" : "PF14640" }, { "signature" : { "accession" : "PTHR14549", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR026100", "name" : "Tmem223", "description" : "Transmembrane protein 223", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 67, "end" : 272, "hmmStart" : 14, "hmmEnd" : 222, "hmmLength" : 222, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 54, "envelopeEnd" : 272, "location-fragments" : [ { "start" : 67, "end" : 272, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-57, "familyName" : "TRANSMEMBRANE PROTEIN 223", "score" : 197.5, "model-ac" : "PTHR14549" }, { "signature" : { "accession" : "PTHR14549:SF2", "name" : "TRANSMEMBRANE PROTEIN 223", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 67, "end" : 272, "hmmStart" : 14, "hmmEnd" : 222, "hmmLength" : 222, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 54, "envelopeEnd" : 272, "location-fragments" : [ { "start" : 67, "end" : 272, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-57, "familyName" : "TRANSMEMBRANE PROTEIN 223", "score" : 197.5, "model-ac" : "PTHR14549:SF2" } ], "xref" : [ { "name" : "XP_018910273.1 PREDICTED: transmembrane protein 223 [Bemisia tabaci]", "id" : "XP_018910273.1" } ] },{ "sequence" : "MTRSLLEIFILMAYLSSIAEVHCDSLCTEKHPTKLNEENCDVYCNSRWGRAPLVNKPWATGKCLQDGDLDRAYCTCSFNDKDLQKFFPTKCFATGAYAPLSEKKALAEEEYLRQVSEMKFEEKFALYAEAYGKSYKSEDETRKRMQIFKDNLIVIDELNEKHKGRGNLVFGVGPFTDLTSEEYKSSIGLLSRQSSSLRPRGLDAWSDSATTGGSSKGYPTSPKKERVSTSPKRGRRSPSRSLSPRRDNPFERSTSRSPSPGRDNPSGRKSRSRSKDDSNASTSGRSGKKTGSGRSKSSPIKGTPRSRSRSTTPRKERLWVGEDPPSSEPLGAPVNRYAPSSSRPLATRWIGKDPEGDSLSDWRDPADTYPEVQNQVWYGRMCRSCWAFAVNSAIEILWALEQKEVTILSAQDLIDCVKECNGCKGGSLKPTLEHIRRVGVAKAKDYPYWADSGTCFGHIPRYLRINHFEQVKRQGEMEAALSHSPLPTGIHQPDELQHYASGIYNSDECLSDEESLNHAVTIVGHYKDAWIVRNTLGTAFGLAGHLLVEKGKCGIGHETFAVYGPELMPQPQPQG", "md5" : "8799c1959df2d2b16218c133163af368", "matches" : [ { "signature" : { "accession" : "PF08246", "name" : "Inhibitor_I29", "description" : "Cathepsin propeptide inhibitor domain (I29)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013201", "name" : "Prot_inhib_I29", "description" : "Cathepsin propeptide inhibitor domain (I29)", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 124, "end" : 183, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-12, "score" : 46.3, "envelopeStart" : 124, "envelopeEnd" : 183, "postProcessed" : true, "location-fragments" : [ { "start" : 124, "end" : 183, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-12, "score" : 47.1, "model-ac" : "PF08246" }, { "signature" : { "accession" : "PTHR12411:SF626", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 128, "end" : 188, "hmmStart" : 34, "hmmEnd" : 90, "hmmLength" : 304, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 97, "envelopeEnd" : 220, "location-fragments" : [ { "start" : 128, "end" : 188, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-43, "familyName" : "", "score" : 151.2, "model-ac" : "PTHR12411:SF626" }, { "signature" : { "accession" : "SM00645", "name" : "pept_c1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 355, "end" : 563, "hmmStart" : 1, "hmmEnd" : 340, "hmmLength" : 340, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-24, "score" : 97.6, "location-fragments" : [ { "start" : 355, "end" : 563, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-24, "score" : 97.6, "model-ac" : "SM00645" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 201, "end" : 339, "location-fragments" : [ { "start" : 201, "end" : 339, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00848", "name" : "Inhibitor_I29_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013201", "name" : "Prot_inhib_I29", "description" : "Cathepsin propeptide inhibitor domain (I29)", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 124, "end" : 183, "hmmStart" : 1, "hmmEnd" : 67, "hmmLength" : 67, "hmmBounds" : "COMPLETE", "evalue" : 1.0E-15, "score" : 68.2, "location-fragments" : [ { "start" : 124, "end" : 183, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-15, "score" : 68.2, "model-ac" : "SM00848" }, { "signature" : { "accession" : "cd02248", "name" : "Peptidase_C1A", "description" : "Peptidase_C1A", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR039417", "name" : "Peptidase_C1A_papain-like", "description" : "Papain-like cysteine endopeptidase", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 361, "end" : 563, "sites" : [ { "description" : "S2 subsite", "numLocations" : 6, "siteLocations" : [ { "start" : 427, "end" : 427, "residue" : "S" }, { "start" : 489, "end" : 489, "residue" : "G" }, { "start" : 519, "end" : 519, "residue" : "A" }, { "start" : 560, "end" : 560, "residue" : "F" }, { "start" : 428, "end" : 428, "residue" : "L" }, { "start" : 516, "end" : 516, "residue" : "L" } ] }, { "description" : "active site", "numLocations" : 4, "siteLocations" : [ { "start" : 385, "end" : 385, "residue" : "C" }, { "start" : 534, "end" : 534, "residue" : "N" }, { "start" : 375, "end" : 375, "residue" : "Q" }, { "start" : 518, "end" : 518, "residue" : "H" } ] } ], "evalue" : 3.44675E-49, "score" : 167.801, "location-fragments" : [ { "start" : 361, "end" : 563, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd02248" }, { "signature" : { "accession" : "PTHR12411", "name" : "CYSTEINE PROTEASE FAMILY C1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 128, "end" : 188, "hmmStart" : 34, "hmmEnd" : 90, "hmmLength" : 304, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 97, "envelopeEnd" : 220, "location-fragments" : [ { "start" : 128, "end" : 188, "dc-status" : "CONTINUOUS" } ] }, { "start" : 360, "end" : 557, "hmmStart" : 116, "hmmEnd" : 299, "hmmLength" : 304, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 344, "envelopeEnd" : 565, "location-fragments" : [ { "start" : 360, "end" : 557, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-43, "familyName" : "", "score" : 151.2, "model-ac" : "PTHR12411" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 279, "end" : 307, "location-fragments" : [ { "start" : 279, "end" : 307, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 201, "end" : 225, "location-fragments" : [ { "start" : 201, "end" : 225, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF54001", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038765", "name" : "Papain-like_cys_pep_sf", "description" : "Papain-like cysteine peptidase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 117, "end" : 197, "hmmLength" : 314, "location-fragments" : [ { "start" : 117, "end" : 197, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.49E-11, "model-ac" : "0053371" }, { "signature" : { "accession" : "G3DSA:3.90.70.10", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 109, "end" : 245, "hmmStart" : 11, "hmmEnd" : 87, "hmmLength" : 316, "hmmBounds" : "COMPLETE", "evalue" : 9.6E-12, "score" : 47.0, "envelopeStart" : 109, "envelopeEnd" : 245, "postProcessed" : true, "location-fragments" : [ { "start" : 109, "end" : 245, "dc-status" : "CONTINUOUS" } ] }, { "start" : 307, "end" : 563, "hmmStart" : 110, "hmmEnd" : 309, "hmmLength" : 316, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-46, "score" : 161.6, "envelopeStart" : 307, "envelopeEnd" : 563, "postProcessed" : true, "location-fragments" : [ { "start" : 307, "end" : 563, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-61, "score" : 210.7, "model-ac" : "4qrvA00" }, { "signature" : { "accession" : "SSF54001", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038765", "name" : "Papain-like_cys_pep_sf", "description" : "Papain-like cysteine peptidase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 358, "end" : 563, "hmmLength" : 302, "location-fragments" : [ { "start" : 358, "end" : 563, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.37E-40, "model-ac" : "0050999" }, { "signature" : { "accession" : "PF00112", "name" : "Peptidase_C1", "description" : "Papain family cysteine protease", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 360, "end" : 561, "hmmStart" : 5, "hmmEnd" : 216, "hmmLength" : 218, "hmmBounds" : "INCOMPLETE", "evalue" : 3.7E-37, "score" : 128.5, "envelopeStart" : 357, "envelopeEnd" : 563, "postProcessed" : true, "location-fragments" : [ { "start" : 360, "end" : 561, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-37, "score" : 129.5, "model-ac" : "PF00112" }, { "signature" : { "accession" : "PTHR12411:SF626", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 360, "end" : 557, "hmmStart" : 116, "hmmEnd" : 299, "hmmLength" : 304, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 344, "envelopeEnd" : 565, "location-fragments" : [ { "start" : 360, "end" : 557, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-43, "familyName" : "", "score" : 151.2, "model-ac" : "PTHR12411:SF626" } ], "xref" : [ { "name" : "XP_018910209.1 PREDICTED: uncharacterized protein LOC109039252 [Bemisia tabaci]", "id" : "XP_018910209.1" } ] },{ "sequence" : "MSDPSEHSKSLCTGKNPEKTSSRYGYSSRSAFAQVIATLIQSWLILENGLLFGAPTLILGALHGNSSAEGLRMNDDEASWFGAIPSICTPLASFASGYLQDRFGRKGVALLANIPILATWLLLYTANSIPALYIGAGMMGLSQGLAEAPIISYTGEISEPHLRGILSTITSTAVMIGMIIMFVLGYYFDWRTATLISAAFPMITIAVMTQIPESPTWLLGKNRLDDAKRSLCWLRGWISNEEIEEEFQNLVNYTRNSAKEDCSATSNGHVQDSCNVKSDGFLKTHYNILTRKNVLRPLRLVMLTAFFTFVAVLVGMRPYYINELKALNSPLDPKLLLIIGQFLFIGGAVTNMAVLWMTGKRKLVLFSYLTAAISILGLAAYSSFLKDSATWVTWIPIVLLCVISFLSGLSILILPWQLSGEVYPPVGRGLATGISAAWTHLVISALIKSYLYMKAWVGFSGVMYLHCGCVVIGFVYLYCNLPETEGKSLEQIETYFTKNVSRREKFSISKATNKSKSLRGDQRL", "md5" : "c167606148b1d144c669d3e6252a3443", "matches" : [ { "signature" : { "accession" : "PTHR23500", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 389, "end" : 504, "hmmStart" : 535, "hmmEnd" : 650, "hmmLength" : 950, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 382, "envelopeEnd" : 522, "location-fragments" : [ { "start" : 389, "end" : 504, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-93, "familyName" : "", "score" : 315.6, "model-ac" : "PTHR23500" }, { "signature" : { "accession" : "SSF103473", "name" : "MFS general substrate transporter", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036259", "name" : "MFS_trans_sf", "description" : "MFS transporter superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 60, "end" : 493, "hmmLength" : 447, "location-fragments" : [ { "start" : 275, "end" : 493, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 60, "end" : 238, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.31E-47, "model-ac" : "0042501" }, { "signature" : { "accession" : "PF00083", "name" : "Sugar_tr", "description" : "Sugar (and other) transporter", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005828", "name" : "MFS_sugar_transport-like", "description" : "Major facilitator, sugar transporter-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 77, "end" : 496, "hmmStart" : 47, "hmmEnd" : 452, "hmmLength" : 452, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 6.8E-42, "score" : 143.9, "envelopeStart" : 27, "envelopeEnd" : 496, "postProcessed" : true, "location-fragments" : [ { "start" : 77, "end" : 496, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-42, "score" : 144.3, "model-ac" : "PF00083" }, { "signature" : { "accession" : "PTHR23500", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 29, "end" : 382, "hmmStart" : 58, "hmmEnd" : 404, "hmmLength" : 950, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 21, "envelopeEnd" : 390, "location-fragments" : [ { "start" : 29, "end" : 382, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-93, "familyName" : "", "score" : 315.6, "model-ac" : "PTHR23500" }, { "signature" : { "accession" : "cd17358", "name" : "MFS_GLUT6_8_Class3_like", "description" : "MFS_GLUT6_8_Class3_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 70, "end" : 491, "sites" : [ { "description" : "chemical substrate binding pocket", "numLocations" : 19, "siteLocations" : [ { "start" : 178, "end" : 178, "residue" : "M" }, { "start" : 407, "end" : 407, "residue" : "S" }, { "start" : 440, "end" : 440, "residue" : "H" }, { "start" : 314, "end" : 314, "residue" : "V" }, { "start" : 411, "end" : 411, "residue" : "I" }, { "start" : 443, "end" : 443, "residue" : "I" }, { "start" : 313, "end" : 313, "residue" : "L" }, { "start" : 171, "end" : 171, "residue" : "S" }, { "start" : 174, "end" : 174, "residue" : "V" }, { "start" : 343, "end" : 343, "residue" : "L" }, { "start" : 308, "end" : 308, "residue" : "T" }, { "start" : 318, "end" : 318, "residue" : "P" }, { "start" : 309, "end" : 309, "residue" : "F" }, { "start" : 408, "end" : 408, "residue" : "G" }, { "start" : 439, "end" : 439, "residue" : "T" }, { "start" : 416, "end" : 416, "residue" : "W" }, { "start" : 175, "end" : 175, "residue" : "M" }, { "start" : 317, "end" : 317, "residue" : "R" }, { "start" : 412, "end" : 412, "residue" : "L" } ] } ], "evalue" : 1.9299E-69, "score" : 227.073, "location-fragments" : [ { "start" : 70, "end" : 491, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd17358" }, { "signature" : { "accession" : "G3DSA:1.20.1250.20", "name" : "MFS general substrate transporter like domains", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 30, "end" : 500, "hmmStart" : 21, "hmmEnd" : 466, "hmmLength" : 470, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-75, "score" : 256.9, "envelopeStart" : 30, "envelopeEnd" : 500, "postProcessed" : true, "location-fragments" : [ { "start" : 30, "end" : 500, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-75, "score" : 257.3, "model-ac" : "4zw9A00" }, { "signature" : { "accession" : "PTHR23500:SF3", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 389, "end" : 504, "hmmStart" : 535, "hmmEnd" : 650, "hmmLength" : 950, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 382, "envelopeEnd" : 522, "location-fragments" : [ { "start" : 389, "end" : 504, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-93, "familyName" : "", "score" : 315.6, "model-ac" : "PTHR23500:SF3" }, { "signature" : { "accession" : "PS50850", "name" : "MFS", "description" : "Major facilitator superfamily (MFS) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR020846", "name" : "MFS_dom", "description" : "Major facilitator superfamily domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 41, "end" : 485, "score" : 23.224, "alignment" : "QSWLILENGLLFGAPTLILgALHGNSSAEGLRMNDDEASWFGAIPSICTPLASFASGYLQDRFGRKGVALLANIPILATWLLLYTANSIPALYIGAGMMGLSQGLAEAPIISYTGEISEPHLRGILSTI----TSTAVMIGMIIMFVLGYYFDWRTATLISAAFPMITIAVM-TQIPESPTWllgknrlddakrslcwlrgwisneeieeefqnlvnytrnsakedcsatsnGHVQDSCNVKSDGFLKTHYNILTRKNvlrPLRLVMLTAFFTF---VAVLVGMRPYYINEL-KALNSPLDPKLLLIIGQFLFIGGAVTNMAVLWMTGKRKLVLFSYLTAAISILGLAAYSSFLKdsatwvtWIPIVLLCVISFLSGLSILILPWQLSGEVYPPVGRGLATGISAAWThlVISALIKSYLYMKAWVGFSG--VMYLHCGCVVIGFVYLYCNLPETE", "location-fragments" : [ { "start" : 41, "end" : 485, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50850" }, { "signature" : { "accession" : "PTHR23500:SF3", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 29, "end" : 382, "hmmStart" : 58, "hmmEnd" : 404, "hmmLength" : 950, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 21, "envelopeEnd" : 390, "location-fragments" : [ { "start" : 29, "end" : 382, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-93, "familyName" : "", "score" : 315.6, "model-ac" : "PTHR23500:SF3" }, { "signature" : { "accession" : "PS00217", "name" : "SUGAR_TRANSPORT_2", "description" : "Sugar transport proteins signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR005829", "name" : "Sugar_transporter_CS", "description" : "Sugar transporter, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 138, "end" : 163, "level" : "STRONG", "cigarAlignment" : "1M1I3M1I2M7I1M2I1M6I1M", "alignment" : "MmGLSqGLaeapiisYtgEisephlR", "location-fragments" : [ { "start" : 138, "end" : 163, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00217" } ], "xref" : [ { "name" : "XP_018909732.1 PREDICTED: facilitated trehalose transporter Tret1-like [Bemisia tabaci]", "id" : "XP_018909732.1" } ] },{ "sequence" : "MYFKLCIIIYFTSLCVGLTYTSSENRNHKDWSSSLKDDIYMDDDEPEGSGQREIKDDLESSGSGYGPDDEDGEGGSGININKQQPTKTKTIVDENPPPSPVDQENVAVRTQNVGVEFAPNGGTGVNEIGPPPAREPTDVEATDDNNRQDNDVTYSPEDRATSFFAQPGILAAVFGGAVVGLLCAILVVMFIVYRMRKKDEGSYALEEPKRSPTSNSYTKNSHREFYA", "md5" : "56ecd2069fdfcbd82c901834203c9a19", "matches" : [ { "signature" : { "accession" : "PS00964", "name" : "SYNDECAN", "description" : "Syndecans signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR030479", "name" : "Syndecan_CS", "description" : "Syndecan, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "A tetrasaccharide linker sequence is required for GAG synthesis", "databaseName" : "Reactome", "id" : "R-HSA-1971475" }, { "name" : "Cell surface interactions at the vascular wall", "databaseName" : "Reactome", "id" : "R-HSA-202733" }, { "name" : "Defective B3GAT3 causes JDSSDHD", "databaseName" : "Reactome", "id" : "R-HSA-3560801" }, { "name" : "HS-GAG degradation", "databaseName" : "Reactome", "id" : "R-HSA-2024096" }, { "name" : "Defective B3GALT6 causes EDSP2 and SEMDJL1", "databaseName" : "Reactome", "id" : "R-HSA-4420332" }, { "name" : "Defective EXT1 causes exostoses 1, TRPS2 and CHDS", "databaseName" : "Reactome", "id" : "R-HSA-3656253" }, { "name" : "Retinoid metabolism and transport", "databaseName" : "Reactome", "id" : "R-HSA-975634" }, { "name" : "Defective B4GALT7 causes EDS, progeroid type", "databaseName" : "Reactome", "id" : "R-HSA-3560783" }, { "name" : "HS-GAG biosynthesis", "databaseName" : "Reactome", "id" : "R-HSA-2022928" }, { "name" : "Defective EXT2 causes exostoses 2", "databaseName" : "Reactome", "id" : "R-HSA-3656237" }, { "name" : "Syndecan interactions", "databaseName" : "Reactome", "id" : "R-HSA-3000170" } ] } }, "locations" : [ { "start" : 193, "end" : 203, "level" : "STRONG", "cigarAlignment" : "11M", "alignment" : "YRMRKKDEGSY", "location-fragments" : [ { "start" : 193, "end" : 203, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00964" }, { "signature" : { "accession" : "PF01034", "name" : "Syndecan", "description" : "Syndecan domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR027789", "name" : "Syndecan/Neurexin_dom", "description" : "Syndecan/Neurexin domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 162, "end" : 225, "hmmStart" : 1, "hmmEnd" : 62, "hmmLength" : 62, "hmmBounds" : "COMPLETE", "evalue" : 4.8E-29, "score" : 100.0, "envelopeStart" : 162, "envelopeEnd" : 225, "postProcessed" : true, "location-fragments" : [ { "start" : 162, "end" : 225, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-29, "score" : 100.8, "model-ac" : "PF01034" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 37, "end" : 59, "location-fragments" : [ { "start" : 37, "end" : 59, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR10915", "name" : "SYNDECAN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR001050", "name" : "Syndecan", "description" : "Syndecan", "type" : "FAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ { "name" : "A tetrasaccharide linker sequence is required for GAG synthesis", "databaseName" : "Reactome", "id" : "R-HSA-1971475" }, { "name" : "Defective B4GALT7 causes EDS, progeroid type", "databaseName" : "Reactome", "id" : "R-HSA-3560783" }, { "name" : "Defective EXT2 causes exostoses 2", "databaseName" : "Reactome", "id" : "R-HSA-3656237" }, { "name" : "Cell surface interactions at the vascular wall", "databaseName" : "Reactome", "id" : "R-HSA-202733" }, { "name" : "Retinoid metabolism and transport", "databaseName" : "Reactome", "id" : "R-HSA-975634" }, { "name" : "Syndecan interactions", "databaseName" : "Reactome", "id" : "R-HSA-3000170" }, { "name" : "Defective B3GAT3 causes JDSSDHD", "databaseName" : "Reactome", "id" : "R-HSA-3560801" }, { "name" : "HS-GAG biosynthesis", "databaseName" : "Reactome", "id" : "R-HSA-2022928" }, { "name" : "HS-GAG degradation", "databaseName" : "Reactome", "id" : "R-HSA-2024096" }, { "name" : "Defective EXT1 causes exostoses 1, TRPS2 and CHDS", "databaseName" : "Reactome", "id" : "R-HSA-3656253" }, { "name" : "Defective B3GALT6 causes EDSP2 and SEMDJL1", "databaseName" : "Reactome", "id" : "R-HSA-4420332" } ] } }, "locations" : [ { "start" : 83, "end" : 227, "hmmStart" : 137, "hmmEnd" : 279, "hmmLength" : 279, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 74, "envelopeEnd" : 227, "location-fragments" : [ { "start" : 83, "end" : 227, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.2E-54, "familyName" : "SYNDECAN", "score" : 186.7, "model-ac" : "PTHR10915" }, { "signature" : { "accession" : "PTHR10915:SF1", "name" : "SYNDECAN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR031198", "name" : "Syndecan_inverte", "description" : "Syndecan, invertebrate", "type" : "FAMILY", "goXRefs" : [ { "name" : "axon guidance", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007411" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 83, "end" : 227, "hmmStart" : 137, "hmmEnd" : 279, "hmmLength" : 279, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 74, "envelopeEnd" : 227, "location-fragments" : [ { "start" : 83, "end" : 227, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.2E-54, "familyName" : "SYNDECAN", "score" : 186.7, "model-ac" : "PTHR10915:SF1" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 121, "end" : 148, "location-fragments" : [ { "start" : 121, "end" : 148, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00294", "name" : "4.1m_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003585", "name" : "Neurexin-like", "description" : "Neurexin/syndecan/glycophorin C", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 192, "end" : 210, "hmmStart" : 1, "hmmEnd" : 19, "hmmLength" : 19, "hmmBounds" : "COMPLETE", "evalue" : 0.0016, "score" : 27.7, "location-fragments" : [ { "start" : 192, "end" : 210, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0016, "score" : 27.7, "model-ac" : "SM00294" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 77, "end" : 93, "location-fragments" : [ { "start" : 77, "end" : 93, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 37, "end" : 101, "location-fragments" : [ { "start" : 37, "end" : 101, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910337.1 PREDICTED: syndecan-like [Bemisia tabaci]", "id" : "XP_018910337.1" } ] },{ "sequence" : "MKGSEVALTINGVLYKVPESLPADTTLNEFIRTAAHLKGTKFMCLEGGCGACIVTAKRKDPATGKDLIFAVNSCLTPIFACHGWAITTVEGIGSKATGYNKVQSRLASFSGTQCGYCSPGMVMNMYSLMKGNEQVTMKAVENSFGGNICRCTGYRPILDAFKSLCTDSPKDFYPDKCADIEDFPKVCPKTAEICTKICNDKNRCHTDEHFNEEYDFLYVDNLALSLANNTKWYKVDGKKEIFEIFDMIDDPQSYQLVAGNTAHGVYRNSDFDFYIDINSVAELSDWNLQDNALNLGANITLTKAMSIFESVSKKYPKFSYLKAFADHIDLIANVPVRNVGTLAGNLSIKNQHTEFPSDIYLMFVTVGAMYTYETPMGSSDIREVEELIETDMRKKLITSFVLPSLDDSYIVKTYKIMPRAQNAHAYVNAGFKIKLGNKDTMTVSEASIVYGGIRRNFVHASQTENFLVGKSLLDSHVVQGALDKLASEVDPDVVLTDASPAYRKGLAQSLFYKFVLSLKPTSISPKYRSGGEKLVRPLSSGKQSFDSDEKMWPVNKAMPKLEAYSQCSGEAEFSNDVLAPPGELYGAFVLAPVGPGILDSIDTSASMAMNGVKSFFSAKNIPGLNSFTPVDAATGAQENELLFAEKEVLFAGQPVGLLIATSQHLANKAAKRVKVHVKDVKKPLTSTQEVLSSGDKSRIKPIKTVERKLENAASGKNIIKGVFEIKEQYHFTMETQVCLAVPTEEGLDVYPSSQFLSMIQRSISQCLKLPENCINVQNRRVGGGYGSKISRNSQVATACALAAYILRKPVRVMLTIETNMQSVGKRIPCLSTYEVSVDDAGKIQYLNLDIHQDLGSSWNENAVSGTLAFLASGYDSRTWNINGFAVRTDKSSNTWCRAPGSAEAIATIEHILDHIATVLNKDPVDVRTANFSDDYKEQLVAMITQLKETSDFDNRKQQIKEFNEKNRWRKKGISLVPMRYPMGLWGNYHALISIYQSDGTVSIAHGGIEMGQGINTKAAQVCAYKFGIDVSMVKIKPTNVLTAPNNAVSGGSMASEAVSLGVIKCCDVLLARLAPIKAKLGPDADWQKIIGTAAAENVDLCANYMYTNKDFGEKVSSYDIFGVAALEVEVDVLTGNYLIQRCDIIEDAGVSLSPEVDIGQVEGAFVMGLGYWLTEEIIFDPNTGSVLTDRTWNYKPPGAKDIPVDLHVTLLKNGSNPVGVLRSKATGEPPLCMSCGVMFALRDAINSSLADAGKQKQWIDIKVPFTPEKVFLAASAGTQEYKL", "md5" : "c14c27f9efb85392cff922d2d2f84673", "matches" : [ { "signature" : { "accession" : "PTHR11908", "name" : "XANTHINE DEHYDROGENASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4, "end" : 1279, "hmmStart" : 2, "hmmEnd" : 1177, "hmmLength" : 1181, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 1283, "location-fragments" : [ { "start" : 4, "end" : 1279, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "ALDEHYDE OXIDASE 1-RELATED", "score" : 1479.4, "model-ac" : "PTHR11908" }, { "signature" : { "accession" : "SSF54292", "name" : "2Fe-2S ferredoxin-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036010", "name" : "2Fe-2S_ferredoxin-like_sf", "description" : "2Fe-2S ferredoxin-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "electron transfer activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0009055" }, { "name" : "iron-sulfur cluster binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0051536" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5, "end" : 92, "hmmLength" : 90, "location-fragments" : [ { "start" : 5, "end" : 92, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.78E-15, "model-ac" : "0037699" }, { "signature" : { "accession" : "PF00111", "name" : "Fer2", "description" : "2Fe-2S iron-sulfur cluster binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001041", "name" : "2Fe-2S_ferredoxin-type", "description" : "2Fe-2S ferredoxin-type iron-sulfur binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "electron transfer activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0009055" }, { "name" : "iron-sulfur cluster binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0051536" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 22, "end" : 77, "hmmStart" : 11, "hmmEnd" : 76, "hmmLength" : 78, "hmmBounds" : "INCOMPLETE", "evalue" : 4.5E-4, "score" : 20.1, "envelopeStart" : 8, "envelopeEnd" : 78, "postProcessed" : true, "location-fragments" : [ { "start" : 22, "end" : 77, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-4, "score" : 21.4, "model-ac" : "PF00111" }, { "signature" : { "accession" : "SSF54665", "name" : "CO dehydrogenase molybdoprotein N-domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036856", "name" : "Ald_Oxase/Xan_DH_a/b_sf", "description" : "Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 527, "end" : 678, "hmmLength" : 158, "location-fragments" : [ { "start" : 527, "end" : 678, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.11E-33, "model-ac" : "0046832" }, { "signature" : { "accession" : "SSF55447", "name" : "CO dehydrogenase flavoprotein C-terminal domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036683", "name" : "CO_DH_flav_C_dom_sf", "description" : "CO dehydrogenase flavoprotein, C-terminal domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 410, "end" : 519, "hmmLength" : 117, "location-fragments" : [ { "start" : 410, "end" : 519, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.72E-28, "model-ac" : "0037701" }, { "signature" : { "accession" : "PF01799", "name" : "Fer2_2", "description" : "[2Fe-2S] binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002888", "name" : "2Fe-2S-bd", "description" : "[2Fe-2S]-binding", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" }, { "name" : "metal ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046872" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 88, "end" : 161, "hmmStart" : 1, "hmmEnd" : 75, "hmmLength" : 76, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.8E-24, "score" : 83.9, "envelopeStart" : 88, "envelopeEnd" : 162, "postProcessed" : true, "location-fragments" : [ { "start" : 88, "end" : 161, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-24, "score" : 85.1, "model-ac" : "PF01799" }, { "signature" : { "accession" : "PF02738", "name" : "Ald_Xan_dh_C2", "description" : "Molybdopterin-binding domain of aldehyde dehydrogenase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR008274", "name" : "AldOxase/xan_DH_Mopterin-bd", "description" : "Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 714, "end" : 1203, "hmmStart" : 24, "hmmEnd" : 552, "hmmLength" : 552, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.4E-128, "score" : 427.4, "envelopeStart" : 694, "envelopeEnd" : 1203, "postProcessed" : true, "location-fragments" : [ { "start" : 714, "end" : 1203, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-128, "score" : 428.9, "model-ac" : "PF02738" }, { "signature" : { "accession" : "PS00197", "name" : "2FE2S_FER_1", "description" : "2Fe-2S ferredoxin-type iron-sulfur binding region signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR006058", "name" : "2Fe2S_fd_BS", "description" : "2Fe-2S ferredoxin, iron-sulphur binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "2 iron, 2 sulfur cluster binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0051537" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 52, "level" : "STRONG", "cigarAlignment" : "9M", "alignment" : "CLEGGCGAC", "location-fragments" : [ { "start" : 44, "end" : 52, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00197" }, { "signature" : { "accession" : "SSF56003", "name" : "Molybdenum cofactor-binding domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR037165", "name" : "AldOxase/xan_DH_Mopterin-bd_sf", "description" : "Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 713, "end" : 1274, "hmmLength" : 654, "location-fragments" : [ { "start" : 713, "end" : 1274, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.14E-143, "model-ac" : "0039729" }, { "signature" : { "accession" : "SM01008", "name" : "Ald_Xan_dh_C_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000674", "name" : "Ald_Oxase/Xan_DH_a/b", "description" : "Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 568, "end" : 681, "hmmStart" : 1, "hmmEnd" : 136, "hmmLength" : 136, "hmmBounds" : "COMPLETE", "evalue" : 7.4E-30, "score" : 115.2, "location-fragments" : [ { "start" : 568, "end" : 681, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-30, "score" : 115.2, "model-ac" : "SM01008" }, { "signature" : { "accession" : "PTHR11908:SF132", "name" : "ALDEHYDE OXIDASE 1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4, "end" : 1279, "hmmStart" : 2, "hmmEnd" : 1177, "hmmLength" : 1181, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 1283, "location-fragments" : [ { "start" : 4, "end" : 1279, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "ALDEHYDE OXIDASE 1-RELATED", "score" : 1479.4, "model-ac" : "PTHR11908:SF132" }, { "signature" : { "accession" : "G3DSA:3.30.365.10", "name" : "Aldehyde Oxidoreductase; domain 4", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 1282, "hmmStart" : 4, "hmmEnd" : 1310, "hmmLength" : 1333, "hmmBounds" : "COMPLETE", "evalue" : 0.0, "score" : 1242.6, "envelopeStart" : 1, "envelopeEnd" : 1282, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 1282, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "score" : 1242.9, "model-ac" : "2ckjB00" }, { "signature" : { "accession" : "SSF56176", "name" : "FAD-binding/transporter-associated domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036318", "name" : "FAD-bd_PCMH-like_sf", "description" : "FAD-binding, type PCMH-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "flavin adenine dinucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0050660" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 227, "end" : 403, "hmmLength" : 216, "location-fragments" : [ { "start" : 227, "end" : 403, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.38E-25, "model-ac" : "0049208" }, { "signature" : { "accession" : "PIRSF000127", "name" : "Xanthine_dh", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR016208", "name" : "Ald_Oxase/xanthine_DH", "description" : "Aldehyde oxidase/xanthine dehydrogenase", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 1282, "hmmStart" : 3, "hmmEnd" : 1275, "hmmLength" : 1331, "hmmBounds" : "INCOMPLETE", "evalue" : 0.0, "score" : 1295.6, "envelopeStart" : 1, "envelopeEnd" : 1282, "postProcessed" : false, "location-fragments" : [ { "start" : 1, "end" : 1282, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "score" : 1296.0, "model-ac" : "PIRSF000127" }, { "signature" : { "accession" : "PS51387", "name" : "FAD_PCMH", "description" : "PCMH-type FAD-binding domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR016166", "name" : "FAD-bd_PCMH", "description" : "FAD-binding domain, PCMH-type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "FAD binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0071949" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 225, "end" : 407, "score" : 15.688, "alignment" : "SLANNTKWYKVDGKKEIFEIFDMI-DDPQSYQLVAGNTAHGVYRNSD--FDFYIDINSVAELSDWNLQDNALNLGANITLTKAMSIfesvskkyPKFSYLKAFADHIDLIANVPVRNVGTLAGNLSiknQHTEFPSDIYLMFVTVGAMYTYETPMGSSDIREVEELIE----TDMRKKLITSFVLPSLDD", "location-fragments" : [ { "start" : 225, "end" : 407, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51387" }, { "signature" : { "accession" : "PF00941", "name" : "FAD_binding_5", "description" : "FAD binding domain in molybdopterin dehydrogenase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002346", "name" : "Mopterin_DH_FAD-bd", "description" : "Molybdopterin dehydrogenase, FAD-binding", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 231, "end" : 404, "hmmStart" : 4, "hmmEnd" : 170, "hmmLength" : 171, "hmmBounds" : "INCOMPLETE", "evalue" : 3.4E-21, "score" : 75.7, "envelopeStart" : 228, "envelopeEnd" : 405, "postProcessed" : true, "location-fragments" : [ { "start" : 231, "end" : 404, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-21, "score" : 77.0, "model-ac" : "PF00941" }, { "signature" : { "accession" : "PF01315", "name" : "Ald_Xan_dh_C", "description" : "Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000674", "name" : "Ald_Oxase/Xan_DH_a/b", "description" : "Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 568, "end" : 677, "hmmStart" : 1, "hmmEnd" : 106, "hmmLength" : 110, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.4E-19, "score" : 70.4, "envelopeStart" : 568, "envelopeEnd" : 681, "postProcessed" : true, "location-fragments" : [ { "start" : 568, "end" : 677, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-20, "score" : 71.6, "model-ac" : "PF01315" }, { "signature" : { "accession" : "PF03450", "name" : "CO_deh_flav_C", "description" : "CO dehydrogenase flavoprotein C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005107", "name" : "CO_DH_flav_C", "description" : "CO dehydrogenase flavoprotein, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 412, "end" : 517, "hmmStart" : 1, "hmmEnd" : 102, "hmmLength" : 103, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.0E-26, "score" : 91.1, "envelopeStart" : 412, "envelopeEnd" : 518, "postProcessed" : true, "location-fragments" : [ { "start" : 412, "end" : 517, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-26, "score" : 92.6, "model-ac" : "PF03450" }, { "signature" : { "accession" : "SM01092", "name" : "CO_deh_flav_C_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR005107", "name" : "CO_DH_flav_C", "description" : "CO dehydrogenase flavoprotein, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 412, "end" : 518, "hmmStart" : 1, "hmmEnd" : 118, "hmmLength" : 118, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-20, "score" : 83.3, "location-fragments" : [ { "start" : 412, "end" : 518, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-20, "score" : 83.3, "model-ac" : "SM01092" }, { "signature" : { "accession" : "SSF47741", "name" : "CO dehydrogenase ISP C-domain like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036884", "name" : "2Fe-2S-bd_dom_sf", "description" : "[2Fe-2S]-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 100, "end" : 172, "hmmLength" : 113, "location-fragments" : [ { "start" : 100, "end" : 172, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.22E-28, "model-ac" : "0044863" } ], "xref" : [ { "name" : "XP_018909622.1 PREDICTED: xanthine dehydrogenase-like [Bemisia tabaci]", "id" : "XP_018909622.1" } ] },{ "sequence" : "MTGDLGLTMPETSLVNGYQGNGHMEPEIPDGENFLFTSESVGEGHPDKMCDQISDAILDAHLKEDPDAKVACETVTKTGMVLLCGEITSKANVDYQKVVRDTIKHIGYDDSSKGFDYETCNVLVAMDAQSPNIAEGVHVNRAEDMIGAGDQGLMFGYATDETEECMPLTVVLAHKLNERIADMRRSGVFWWARPDSKTQVTCEYCFQHGACVPLRVHTVVVSIQHSEKITLEELRTEIMNKVIKEVIPTKYLDDKTMFHINPCGQFVLGGPRCDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKSGLCRRCLVQVSYAIGVAEPISITLFEYGTAKKTQKELLEIVKRNFDLRPGKIVRDLNLRNPIYQKTSTYGHFGRDIFPWEQPKLLV", "md5" : "407c2fec504b9da7f03d26a4c2b9726b", "matches" : [ { "signature" : { "accession" : "cd18079", "name" : "S-AdoMet_synt", "description" : "S-AdoMet_synt", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 407, "sites" : [ { "description" : "active site", "numLocations" : 28, "siteLocations" : [ { "start" : 195, "end" : 195, "residue" : "D" }, { "start" : 222, "end" : 222, "residue" : "S" }, { "start" : 86, "end" : 86, "residue" : "E" }, { "start" : 295, "end" : 295, "residue" : "G" }, { "start" : 45, "end" : 45, "residue" : "H" }, { "start" : 305, "end" : 305, "residue" : "K" }, { "start" : 280, "end" : 280, "residue" : "R" }, { "start" : 133, "end" : 133, "residue" : "I" }, { "start" : 296, "end" : 296, "residue" : "G" }, { "start" : 47, "end" : 47, "residue" : "D" }, { "start" : 266, "end" : 266, "residue" : "F" }, { "start" : 263, "end" : 263, "residue" : "C" }, { "start" : 307, "end" : 307, "residue" : "D" }, { "start" : 39, "end" : 39, "residue" : "E" }, { "start" : 265, "end" : 265, "residue" : "Q" }, { "start" : 301, "end" : 301, "residue" : "K" }, { "start" : 338, "end" : 338, "residue" : "I" }, { "start" : 274, "end" : 274, "residue" : "D" }, { "start" : 149, "end" : 149, "residue" : "G" }, { "start" : 132, "end" : 132, "residue" : "N" }, { "start" : 150, "end" : 150, "residue" : "D" }, { "start" : 46, "end" : 46, "residue" : "P" }, { "start" : 297, "end" : 297, "residue" : "A" }, { "start" : 129, "end" : 129, "residue" : "Q" }, { "start" : 197, "end" : 197, "residue" : "K" }, { "start" : 71, "end" : 71, "residue" : "A" }, { "start" : 268, "end" : 268, "residue" : "L" }, { "start" : 281, "end" : 281, "residue" : "K" } ] }, { "description" : "ATP binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 195, "end" : 195, "residue" : "D" }, { "start" : 46, "end" : 46, "residue" : "P" }, { "start" : 39, "end" : 39, "residue" : "E" }, { "start" : 197, "end" : 197, "residue" : "K" }, { "start" : 45, "end" : 45, "residue" : "H" }, { "start" : 281, "end" : 281, "residue" : "K" } ] }, { "description" : "homodimer interface", "numLocations" : 50, "siteLocations" : [ { "start" : 295, "end" : 295, "residue" : "G" }, { "start" : 35, "end" : 35, "residue" : "L" }, { "start" : 218, "end" : 218, "residue" : "T" }, { "start" : 37, "end" : 37, "residue" : "T" }, { "start" : 259, "end" : 259, "residue" : "H" }, { "start" : 333, "end" : 333, "residue" : "Q" }, { "start" : 75, "end" : 75, "residue" : "V" }, { "start" : 84, "end" : 84, "residue" : "C" }, { "start" : 290, "end" : 290, "residue" : "W" }, { "start" : 344, "end" : 344, "residue" : "I" }, { "start" : 339, "end" : 339, "residue" : "G" }, { "start" : 278, "end" : 278, "residue" : "T" }, { "start" : 289, "end" : 289, "residue" : "G" }, { "start" : 345, "end" : 345, "residue" : "S" }, { "start" : 39, "end" : 39, "residue" : "E" }, { "start" : 36, "end" : 36, "residue" : "F" }, { "start" : 301, "end" : 301, "residue" : "K" }, { "start" : 338, "end" : 338, "residue" : "I" }, { "start" : 274, "end" : 274, "residue" : "D" }, { "start" : 283, "end" : 283, "residue" : "I" }, { "start" : 199, "end" : 199, "residue" : "Q" }, { "start" : 292, "end" : 292, "residue" : "A" }, { "start" : 150, "end" : 150, "residue" : "D" }, { "start" : 197, "end" : 197, "residue" : "K" }, { "start" : 152, "end" : 152, "residue" : "G" }, { "start" : 155, "end" : 155, "residue" : "F" }, { "start" : 291, "end" : 291, "residue" : "G" }, { "start" : 347, "end" : 347, "residue" : "T" }, { "start" : 86, "end" : 86, "residue" : "E" }, { "start" : 262, "end" : 262, "residue" : "P" }, { "start" : 273, "end" : 273, "residue" : "C" }, { "start" : 151, "end" : 151, "residue" : "Q" }, { "start" : 294, "end" : 294, "residue" : "G" }, { "start" : 153, "end" : 153, "residue" : "L" }, { "start" : 82, "end" : 82, "residue" : "L" }, { "start" : 280, "end" : 280, "residue" : "R" }, { "start" : 201, "end" : 201, "residue" : "T" }, { "start" : 336, "end" : 336, "residue" : "Y" }, { "start" : 293, "end" : 293, "residue" : "H" }, { "start" : 220, "end" : 220, "residue" : "V" }, { "start" : 337, "end" : 337, "residue" : "A" }, { "start" : 277, "end" : 277, "residue" : "L" }, { "start" : 77, "end" : 77, "residue" : "K" }, { "start" : 279, "end" : 279, "residue" : "G" }, { "start" : 288, "end" : 288, "residue" : "G" }, { "start" : 85, "end" : 85, "residue" : "G" }, { "start" : 73, "end" : 73, "residue" : "E" }, { "start" : 275, "end" : 275, "residue" : "A" }, { "start" : 297, "end" : 297, "residue" : "A" }, { "start" : 335, "end" : 335, "residue" : "S" } ] } ], "evalue" : 0.0, "score" : 679.125, "location-fragments" : [ { "start" : 35, "end" : 407, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18079" }, { "signature" : { "accession" : "PF02773", "name" : "S-AdoMet_synt_C", "description" : "S-adenosylmethionine synthetase, C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022630", "name" : "S-AdoMet_synt_C", "description" : "S-adenosylmethionine synthetase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" } ], "pathwayXRefs" : [ { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 268, "end" : 405, "hmmStart" : 1, "hmmEnd" : 138, "hmmLength" : 138, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-66, "score" : 221.7, "envelopeStart" : 268, "envelopeEnd" : 405, "postProcessed" : true, "location-fragments" : [ { "start" : 268, "end" : 405, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-66, "score" : 222.9, "model-ac" : "PF02773" }, { "signature" : { "accession" : "PS00376", "name" : "ADOMET_SYNTHASE_1", "description" : "S-adenosylmethionine synthase signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR022631", "name" : "ADOMET_SYNTHASE_CS", "description" : "S-adenosylmethionine synthetase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" } ] } }, "locations" : [ { "start" : 147, "end" : 157, "level" : "STRONG", "cigarAlignment" : "6M3I2M", "alignment" : "GAGDQGlmfGY", "location-fragments" : [ { "start" : 147, "end" : 157, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00376" }, { "signature" : { "accession" : "PF02772", "name" : "S-AdoMet_synt_M", "description" : "S-adenosylmethionine synthetase, central domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022629", "name" : "S-AdoMet_synt_central", "description" : "S-adenosylmethionine synthetase, central domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" } ] } }, "locations" : [ { "start" : 146, "end" : 266, "hmmStart" : 2, "hmmEnd" : 120, "hmmLength" : 120, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 8.0E-45, "score" : 152.0, "envelopeStart" : 145, "envelopeEnd" : 266, "postProcessed" : true, "location-fragments" : [ { "start" : 146, "end" : 266, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-45, "score" : 152.8, "model-ac" : "PF02772" }, { "signature" : { "accession" : "PS00377", "name" : "ADOMET_SYNTHASE_2", "description" : "S-adenosylmethionine synthase signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR022631", "name" : "ADOMET_SYNTHASE_CS", "description" : "S-adenosylmethionine synthetase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" } ] } }, "locations" : [ { "start" : 294, "end" : 302, "level" : "STRONG", "cigarAlignment" : "6M1I2M", "alignment" : "GGGAFSgKD", "location-fragments" : [ { "start" : 294, "end" : 302, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00377" }, { "signature" : { "accession" : "SSF55973", "name" : "S-adenosylmethionine synthetase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR022636", "name" : "S-AdoMet_synthetase_sfam", "description" : "S-adenosylmethionine synthetase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" } ], "pathwayXRefs" : [ { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 144, "end" : 267, "hmmLength" : 126, "location-fragments" : [ { "start" : 144, "end" : 267, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.93E-50, "model-ac" : "0054442" }, { "signature" : { "accession" : "G3DSA:3.30.300.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 145, "end" : 404, "hmmStart" : 1, "hmmEnd" : 368, "hmmLength" : 128, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.3E-173, "score" : 578.4, "envelopeStart" : 35, "envelopeEnd" : 404, "postProcessed" : true, "location-fragments" : [ { "start" : 308, "end" : 404, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 145, "end" : 167, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.0E-173, "score" : 578.5, "model-ac" : "5a1iA03" }, { "signature" : { "accession" : "G3DSA:3.30.300.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 41, "end" : 307, "hmmStart" : 1, "hmmEnd" : 368, "hmmLength" : 141, "hmmBounds" : "INCOMPLETE", "evalue" : 2.3E-173, "score" : 578.4, "envelopeStart" : 35, "envelopeEnd" : 404, "postProcessed" : true, "location-fragments" : [ { "start" : 271, "end" : 307, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 41, "end" : 144, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.0E-173, "score" : 578.5, "model-ac" : "5a1iA02" }, { "signature" : { "accession" : "PTHR11964:SF11", "name" : "S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 409, "hmmStart" : 9, "hmmEnd" : 394, "hmmLength" : 396, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 16, "envelopeEnd" : 410, "location-fragments" : [ { "start" : 24, "end" : 409, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-219, "familyName" : "S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1", "score" : 729.3, "model-ac" : "PTHR11964:SF11" }, { "signature" : { "accession" : "G3DSA:3.30.300.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 270, "hmmStart" : 1, "hmmEnd" : 368, "hmmLength" : 125, "hmmBounds" : "INCOMPLETE", "evalue" : 2.3E-173, "score" : 578.4, "envelopeStart" : 35, "envelopeEnd" : 404, "postProcessed" : true, "location-fragments" : [ { "start" : 168, "end" : 270, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 35, "end" : 40, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.0E-173, "score" : 578.5, "model-ac" : "5a1iA01" }, { "signature" : { "accession" : "MF_00086", "name" : "S_AdoMet_synth1", "description" : "S-adenosylmethionine synthase [metK].", "signatureLibraryRelease" : { "library" : "HAMAP", "version" : "2020_01" }, "entry" : { "accession" : "IPR002133", "name" : "S-AdoMet_synthetase", "description" : "S-adenosylmethionine synthetase", "type" : "FAMILY", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 32, "end" : 410, "score" : 49.917, "alignment" : "ENFLFTSESVGEGHPDKMCDQISDAILDAHLKEDPDAKVACETVTKTGMVLLCGEITSKANVDYQKVVRDTIKHIGYDDSSKGFDYETCNVLVAMDAQSPNIAEGVHVNRAeDMIGAGDQGLMFGYATDETEECMPLTVVLAHKLNERIADMRRSGVFWWARPDSKTQVTCEYCFQHgacvPLRVHTVVVSIQHSEKITLEELRTEIMNKVIKEVIPTKYLDD-KTMFHINPCGQFVLGGPRCDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKSGLCRRCLVQVSYAIGVAEPISITLFEYGTAKKTQKELLEIVKRNFDLRPGKIVRDLNLRNPIYQKTSTYGHFGRDIFPWEQP------KLLV", "location-fragments" : [ { "start" : 32, "end" : 410, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "MF_00086" }, { "signature" : { "accession" : "SSF55973", "name" : "S-adenosylmethionine synthetase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR022636", "name" : "S-AdoMet_synthetase_sfam", "description" : "S-adenosylmethionine synthetase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" } ], "pathwayXRefs" : [ { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 33, "end" : 140, "hmmLength" : 110, "location-fragments" : [ { "start" : 33, "end" : 140, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.33E-47, "model-ac" : "0054441" }, { "signature" : { "accession" : "PIRSF000497", "name" : "MAT", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR002133", "name" : "S-AdoMet_synthetase", "description" : "S-adenosylmethionine synthetase", "type" : "FAMILY", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 29, "end" : 410, "hmmStart" : 32, "hmmEnd" : 408, "hmmLength" : 389, "hmmBounds" : "INCOMPLETE", "evalue" : 1.1E-162, "score" : 537.1, "envelopeStart" : 29, "envelopeEnd" : 410, "postProcessed" : false, "location-fragments" : [ { "start" : 29, "end" : 410, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.0E-163, "score" : 537.4, "model-ac" : "PIRSF000497" }, { "signature" : { "accession" : "SSF55973", "name" : "S-adenosylmethionine synthetase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR022636", "name" : "S-AdoMet_synthetase_sfam", "description" : "S-adenosylmethionine synthetase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" } ], "pathwayXRefs" : [ { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 268, "end" : 408, "hmmLength" : 152, "location-fragments" : [ { "start" : 268, "end" : 408, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.02E-64, "model-ac" : "0041133" }, { "signature" : { "accession" : "TIGR01034", "name" : "TIGR01034", "description" : "metK: methionine adenosyltransferase", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR002133", "name" : "S-AdoMet_synthetase", "description" : "S-adenosylmethionine synthetase", "type" : "FAMILY", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 35, "end" : 408, "hmmStart" : 1, "hmmEnd" : 369, "hmmLength" : 377, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 9.8E-179, "score" : 592.1, "envelopeStart" : 35, "envelopeEnd" : 410, "postProcessed" : false, "location-fragments" : [ { "start" : 35, "end" : 408, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-179, "score" : 592.3, "model-ac" : "TIGR01034" }, { "signature" : { "accession" : "PF00438", "name" : "S-AdoMet_synt_N", "description" : "S-adenosylmethionine synthetase, N-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022628", "name" : "S-AdoMet_synt_N", "description" : "S-adenosylmethionine synthetase, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" } ] } }, "locations" : [ { "start" : 33, "end" : 131, "hmmStart" : 1, "hmmEnd" : 99, "hmmLength" : 99, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-43, "score" : 147.8, "envelopeStart" : 33, "envelopeEnd" : 131, "postProcessed" : true, "location-fragments" : [ { "start" : 33, "end" : 131, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-45, "score" : 153.5, "model-ac" : "PF00438" }, { "signature" : { "accession" : "PTHR11964", "name" : "S-ADENOSYLMETHIONINE SYNTHETASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR002133", "name" : "S-AdoMet_synthetase", "description" : "S-adenosylmethionine synthetase", "type" : "FAMILY", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 24, "end" : 409, "hmmStart" : 9, "hmmEnd" : 394, "hmmLength" : 396, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 16, "envelopeEnd" : 410, "location-fragments" : [ { "start" : 24, "end" : 409, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-219, "familyName" : "S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1", "score" : 729.3, "model-ac" : "PTHR11964" } ], "xref" : [ { "name" : "XP_018910511.1 PREDICTED: S-adenosylmethionine synthase isoform X3 [Bemisia tabaci]", "id" : "XP_018910511.1" }, { "name" : "XP_018910509.1 PREDICTED: S-adenosylmethionine synthase isoform X3 [Bemisia tabaci]", "id" : "XP_018910509.1" } ] },{ "sequence" : "MITSKYLLLIIFYLHCVRCSLKPETKHDDILPPCSSCKVLVESFMKGVKRTSRENFAGGDAAWEEEKLGTYATSEVRLIEIQEKLCSEVGRGKDQCLTLSETHEALLEDWWFNEQKVSPDLKQWLCVDLLKVCCPAGHFGADCQPCPGFPKVCFGNGKCKGDGTRKGNGACICDAGYTGEYCDACGPGYYQSYKDDDKLLCSKCHPACSGNCTEAGTKGCEACNEGWAMTAENGCVDVNECVLPDVCKHNQFCVNEEGNYSCIECDAACSGCYGDGPDMCIKCAPGYFLQDNFCVVMTARQWAQTSTLTRYLTYFGLCVATCIIFQKNVIVASVIGLAVAVYVSVSEYMLSSINNEPQMLSGLDFNKLFAKT", "md5" : "07ae0819b480dcf2079fc43b5897f410", "matches" : [ { "signature" : { "accession" : "PS01248", "name" : "EGF_LAM_1", "description" : "Laminin-type EGF-like (LE) domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR002049", "name" : "Laminin_EGF", "description" : "Laminin EGF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 171, "end" : 204, "level" : "STRONG", "cigarAlignment" : "1M1I1M5I1M2I1M2I1M4I1M13I1M", "alignment" : "CiCdagytGeyCdaCgpgyYqsykdddkllcskC", "location-fragments" : [ { "start" : 171, "end" : 204, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01248" }, { "signature" : { "accession" : "SSF57184", "name" : "Growth factor receptor domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009030", "name" : "Growth_fac_rcpt_cys_sf", "description" : "Growth factor receptor cysteine-rich domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 179, "end" : 297, "hmmLength" : 145, "location-fragments" : [ { "start" : 179, "end" : 297, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.57E-14, "model-ac" : "0048103" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 142, "end" : 183, "score" : 10.747, "alignment" : "DCQPCPgfpKVCFGNGKCKGDGTrKGNGACICDAGYTGEYCD", "location-fragments" : [ { "start" : 142, "end" : 183, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01187", "name" : "EGF_CA", "description" : "Calcium-binding EGF-like domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018097", "name" : "EGF_Ca-bd_CS", "description" : "EGF-like calcium-binding, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 237, "end" : 262, "level" : "STRONG", "cigarAlignment" : "1M1I3M5I1M5I1M1I1M4I1M1I1M", "alignment" : "DvNECvlpdvCkhnqfCvNeegnYsC", "location-fragments" : [ { "start" : 237, "end" : 262, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01187" }, { "signature" : { "accession" : "SM00261", "name" : "furin_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006212", "name" : "Furin_repeat", "description" : "Furin-like repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 198, "end" : 253, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 2.4, "score" : 17.1, "location-fragments" : [ { "start" : 198, "end" : 253, "dc-status" : "CONTINUOUS" } ] }, { "start" : 259, "end" : 303, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-5, "score" : 34.7, "location-fragments" : [ { "start" : 259, "end" : 303, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.7E-11, "score" : 51.8, "model-ac" : "SM00261" }, { "signature" : { "accession" : "PTHR24034", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 295, "hmmStart" : 22, "hmmEnd" : 289, "hmmLength" : 353, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 308, "location-fragments" : [ { "start" : 25, "end" : 295, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-65, "familyName" : "CYSTEINE-RICH WITH EGF-LIKE DOMAIN PROTEIN 2", "score" : 223.8, "model-ac" : "PTHR24034" }, { "signature" : { "accession" : "cd00064", "name" : "FU", "description" : "FU", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR006212", "name" : "Furin_repeat", "description" : "Furin-like repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 264, "end" : 295, "sites" : [ ], "evalue" : 7.58571E-5, "score" : 37.8836, "location-fragments" : [ { "start" : 264, "end" : 295, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00064" }, { "signature" : { "accession" : "G3DSA:2.10.220.10", "name" : "Hormone Receptor", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 211, "end" : 316, "hmmStart" : 8, "hmmEnd" : 96, "hmmLength" : 120, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-5, "score" : 25.7, "envelopeStart" : 211, "envelopeEnd" : 316, "postProcessed" : true, "location-fragments" : [ { "start" : 211, "end" : 316, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-5, "score" : 25.7, "model-ac" : "4ufrB00" }, { "signature" : { "accession" : "PTHR24034:SF110", "name" : "CYSTEINE-RICH WITH EGF-LIKE DOMAIN PROTEIN 2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 295, "hmmStart" : 22, "hmmEnd" : 289, "hmmLength" : 353, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 308, "location-fragments" : [ { "start" : 25, "end" : 295, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-65, "familyName" : "CYSTEINE-RICH WITH EGF-LIKE DOMAIN PROTEIN 2", "score" : 223.8, "model-ac" : "PTHR24034:SF110" }, { "signature" : { "accession" : "PS00022", "name" : "EGF_1", "description" : "EGF-like domain signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 171, "end" : 182, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I1M2I2M1I1M", "alignment" : "CiCdaGytGEyC", "location-fragments" : [ { "start" : 171, "end" : 182, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00022" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 237, "end" : 263, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 237, "end" : 237, "residue" : "D" }, { "start" : 240, "end" : 240, "residue" : "E" }, { "start" : 255, "end" : 255, "residue" : "N" } ] } ], "evalue" : 6.95346E-4, "score" : 34.9198, "location-fragments" : [ { "start" : 237, "end" : 263, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" } ], "xref" : [ { "name" : "XP_018909868.1 PREDICTED: cysteine-rich with EGF-like domain protein 2 isoform X1 [Bemisia tabaci]", "id" : "XP_018909868.1" } ] },{ "sequence" : "MKYILVTGGVISGVGKGVVSSSFGAILRACGLHVTAIKIDPYMNIDAGTFSPYEHGEVFVLDDGGEVDIDLGNYERFLDITLNSDNSITTGKINQQVIAKERKGEYLGKTVQIVPHMSNAIIDWVEDVASRPIKSDGDDDDTPPSVPDVCIVELGGTVGDIEGRPYTEAFRPFSRKHHDSFCVAHVSYVPQPASTKEHKTRPTRQSVKELQDCGLLPDLLVCRSENPIPLPVKEKISSFCNVGLDEVICLHDQSSIYYVPLVLRDQGILEYFQKRLCLEYKVSLSTNVLSSWEALTKKLETVRREVNIVLVGKYIKLHDAYASVIKALQHASLKANYKLNLKFVNAENLEVDAEKTNPDLFHESWMTVCNSDGVIVPGGFGKRGMEGKIAVIKWCRTLKKPFLGICLGLHAAVIEFARNVLGHKDANSTEMDPECKDPVISDMPGHTNIDMGGTMRLGRQTTVFSKEHMDYSVVRKLYGNRKEIKERHRHRYEVNQKYLQELESNGLYFVGTDVDGLRMEILELDTDKHPYFIATQFHPEYLSRPMKPSPPFLGFILAATNNLESYLKYGLNQLS", "md5" : "456e4904308ab7fe6a7f922c45dd5445", "matches" : [ { "signature" : { "accession" : "cd01746", "name" : "GATase1_CTP_Synthase", "description" : "GATase1_CTP_Synthase", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR033828", "name" : "GATase1_CTP_Synthase", "description" : "CTP synthase GATase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "CTP biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006241" }, { "name" : "CTP synthase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003883" } ], "pathwayXRefs" : [ { "name" : "UTP and CTP de novo biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-7176" }, { "name" : "Interconversion of nucleotide di- and triphosphates", "databaseName" : "Reactome", "id" : "R-HSA-499943" }, { "name" : "Pyrimidine metabolism", "databaseName" : "KEGG", "id" : "00240+6.3.4.2" }, { "name" : "UTP and CTP dephosphorylation II", "databaseName" : "MetaCyc", "id" : "PWY-7177" }, { "name" : "UTP and CTP dephosphorylation I", "databaseName" : "MetaCyc", "id" : "PWY-7185" } ] } }, "locations" : [ { "start" : 306, "end" : 556, "sites" : [ { "description" : "active site", "numLocations" : 15, "siteLocations" : [ { "start" : 406, "end" : 406, "residue" : "C" }, { "start" : 491, "end" : 491, "residue" : "R" }, { "start" : 410, "end" : 410, "residue" : "H" }, { "start" : 490, "end" : 490, "residue" : "H" }, { "start" : 538, "end" : 538, "residue" : "H" }, { "start" : 540, "end" : 540, "residue" : "E" }, { "start" : 377, "end" : 377, "residue" : "P" }, { "start" : 379, "end" : 379, "residue" : "G" }, { "start" : 492, "end" : 492, "residue" : "Y" }, { "start" : 407, "end" : 407, "residue" : "L" }, { "start" : 430, "end" : 430, "residue" : "E" }, { "start" : 378, "end" : 378, "residue" : "G" }, { "start" : 380, "end" : 380, "residue" : "F" }, { "start" : 489, "end" : 489, "residue" : "R" }, { "start" : 381, "end" : 381, "residue" : "G" } ] }, { "description" : "putative oxyanion hole", "numLocations" : 2, "siteLocations" : [ { "start" : 407, "end" : 407, "residue" : "L" }, { "start" : 379, "end" : 379, "residue" : "G" } ] }, { "description" : "catalytic triad", "numLocations" : 3, "siteLocations" : [ { "start" : 406, "end" : 406, "residue" : "C" }, { "start" : 538, "end" : 538, "residue" : "H" }, { "start" : 540, "end" : 540, "residue" : "E" } ] } ], "evalue" : 5.63558E-123, "score" : 359.945, "location-fragments" : [ { "start" : 306, "end" : 556, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01746" }, { "signature" : { "accession" : "G3DSA:3.40.50.880", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029062", "name" : "Class_I_gatase-like", "description" : "Class I glutamine amidotransferase-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 302, "end" : 573, "hmmStart" : 3, "hmmEnd" : 262, "hmmLength" : 268, "hmmBounds" : "COMPLETE", "evalue" : 7.5E-107, "score" : 358.6, "envelopeStart" : 302, "envelopeEnd" : 573, "postProcessed" : true, "location-fragments" : [ { "start" : 302, "end" : 573, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-107, "score" : 359.0, "model-ac" : "2vktA00" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 301, "hmmStart" : 10, "hmmEnd" : 296, "hmmLength" : 298, "hmmBounds" : "COMPLETE", "evalue" : 6.6E-127, "score" : 424.5, "envelopeStart" : 1, "envelopeEnd" : 301, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 301, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-127, "score" : 424.9, "model-ac" : "4zdjA01" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 278, "hmmLength" : 273, "location-fragments" : [ { "start" : 1, "end" : 278, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.26E-105, "model-ac" : "0054726" }, { "signature" : { "accession" : "PTHR11550:SF2", "name" : "CTP SYNTHASE 2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 570, "hmmStart" : 1, "hmmEnd" : 558, "hmmLength" : 586, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 575, "location-fragments" : [ { "start" : 1, "end" : 570, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-242, "familyName" : "CTP SYNTHASE 2", "score" : 808.2, "model-ac" : "PTHR11550:SF2" }, { "signature" : { "accession" : "PF00117", "name" : "GATase", "description" : "Glutamine amidotransferase class-I", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR017926", "name" : "GATASE", "description" : "Glutamine amidotransferase", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 317, "end" : 556, "hmmStart" : 2, "hmmEnd" : 189, "hmmLength" : 191, "hmmBounds" : "INCOMPLETE", "evalue" : 4.2E-51, "score" : 173.4, "envelopeStart" : 316, "envelopeEnd" : 558, "postProcessed" : true, "location-fragments" : [ { "start" : 317, "end" : 556, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-51, "score" : 174.2, "model-ac" : "PF00117" }, { "signature" : { "accession" : "SSF52317", "name" : "Class I glutamine amidotransferase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029062", "name" : "Class_I_gatase-like", "description" : "Class I glutamine amidotransferase-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 304, "end" : 563, "hmmLength" : 258, "location-fragments" : [ { "start" : 304, "end" : 563, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-64, "model-ac" : "0049298" }, { "signature" : { "accession" : "TIGR00337", "name" : "TIGR00337", "description" : "PyrG: CTP synthase", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR004468", "name" : "CTP_synthase", "description" : "CTP synthase", "type" : "FAMILY", "goXRefs" : [ { "name" : "CTP synthase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003883" }, { "name" : "pyrimidine nucleotide biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006221" } ], "pathwayXRefs" : [ { "name" : "UTP and CTP dephosphorylation II", "databaseName" : "MetaCyc", "id" : "PWY-7177" }, { "name" : "UTP and CTP dephosphorylation I", "databaseName" : "MetaCyc", "id" : "PWY-7185" }, { "name" : "Interconversion of nucleotide di- and triphosphates", "databaseName" : "Reactome", "id" : "R-HSA-499943" }, { "name" : "UTP and CTP de novo biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-7176" }, { "name" : "Pyrimidine metabolism", "databaseName" : "KEGG", "id" : "00240+6.3.4.2" } ] } }, "locations" : [ { "start" : 1, "end" : 557, "hmmStart" : 3, "hmmEnd" : 525, "hmmLength" : 526, "hmmBounds" : "INCOMPLETE", "evalue" : 2.5E-209, "score" : 694.2, "envelopeStart" : 1, "envelopeEnd" : 558, "postProcessed" : false, "location-fragments" : [ { "start" : 1, "end" : 557, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-209, "score" : 694.4, "model-ac" : "TIGR00337" }, { "signature" : { "accession" : "cd03113", "name" : "CTPS_N", "description" : "CTPS_N", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 274, "sites" : [ { "description" : "dimer interface", "numLocations" : 12, "siteLocations" : [ { "start" : 158, "end" : 158, "residue" : "V" }, { "start" : 199, "end" : 199, "residue" : "K" }, { "start" : 12, "end" : 12, "residue" : "S" }, { "start" : 159, "end" : 159, "residue" : "G" }, { "start" : 201, "end" : 201, "residue" : "R" }, { "start" : 10, "end" : 10, "residue" : "V" }, { "start" : 11, "end" : 11, "residue" : "I" }, { "start" : 13, "end" : 13, "residue" : "G" }, { "start" : 160, "end" : 160, "residue" : "D" }, { "start" : 157, "end" : 157, "residue" : "T" }, { "start" : 205, "end" : 205, "residue" : "Q" }, { "start" : 202, "end" : 202, "residue" : "P" } ] }, { "description" : "active site", "numLocations" : 20, "siteLocations" : [ { "start" : 250, "end" : 250, "residue" : "L" }, { "start" : 17, "end" : 17, "residue" : "G" }, { "start" : 38, "end" : 38, "residue" : "K" }, { "start" : 223, "end" : 223, "residue" : "R" }, { "start" : 256, "end" : 256, "residue" : "I" }, { "start" : 161, "end" : 161, "residue" : "I" }, { "start" : 253, "end" : 253, "residue" : "Q" }, { "start" : 70, "end" : 70, "residue" : "D" }, { "start" : 14, "end" : 14, "residue" : "V" }, { "start" : 153, "end" : 153, "residue" : "E" }, { "start" : 252, "end" : 252, "residue" : "D" }, { "start" : 16, "end" : 16, "residue" : "K" }, { "start" : 12, "end" : 12, "residue" : "S" }, { "start" : 15, "end" : 15, "residue" : "G" }, { "start" : 18, "end" : 18, "residue" : "V" }, { "start" : 13, "end" : 13, "residue" : "G" }, { "start" : 162, "end" : 162, "residue" : "E" }, { "start" : 160, "end" : 160, "residue" : "D" }, { "start" : 251, "end" : 251, "residue" : "H" }, { "start" : 259, "end" : 259, "residue" : "V" } ] } ], "evalue" : 1.46805E-157, "score" : 448.857, "location-fragments" : [ { "start" : 2, "end" : 274, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd03113" }, { "signature" : { "accession" : "PS51273", "name" : "GATASE_TYPE_1", "description" : "Glutamine amidotransferase type 1 domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR017926", "name" : "GATASE", "description" : "Glutamine amidotransferase", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 314, "end" : 565, "score" : 20.943, "alignment" : "YIKLHDAYASVIKALQHASLKANYklNLKFVNAENLevdaektnpdlfheswmtVCNSDGVIVPGGFG----KRGMEGKIAVIKWCRTLKKPFLGICLGLHAAVIEFARnvlghkdanstemdpeckdpvisdmpgHTNIDMGGTMRLGRqttvfskeHMDYSVVRKLYGNRKeiKERHRHRYEVNQkylqelESNGLYFVGTDVDGLRmeILELDTDkHPYFIATQFHPEYLSRPMkpSPPFLGFILAATNNLES", "location-fragments" : [ { "start" : 314, "end" : 565, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51273" }, { "signature" : { "accession" : "PF06418", "name" : "CTP_synth_N", "description" : "CTP synthase N-terminus", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR017456", "name" : "CTP_synthase_N", "description" : "CTP synthase, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "CTP synthase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003883" }, { "name" : "pyrimidine nucleotide biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006221" } ], "pathwayXRefs" : [ { "name" : "Pyrimidine metabolism", "databaseName" : "KEGG", "id" : "00240+6.3.4.2" }, { "name" : "Interconversion of nucleotide di- and triphosphates", "databaseName" : "Reactome", "id" : "R-HSA-499943" }, { "name" : "UTP and CTP de novo biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-7176" }, { "name" : "UTP and CTP dephosphorylation II", "databaseName" : "MetaCyc", "id" : "PWY-7177" }, { "name" : "UTP and CTP dephosphorylation I", "databaseName" : "MetaCyc", "id" : "PWY-7185" } ] } }, "locations" : [ { "start" : 2, "end" : 278, "hmmStart" : 1, "hmmEnd" : 265, "hmmLength" : 265, "hmmBounds" : "COMPLETE", "evalue" : 5.5E-111, "score" : 370.2, "envelopeStart" : 2, "envelopeEnd" : 278, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 278, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-111, "score" : 370.6, "model-ac" : "PF06418" }, { "signature" : { "accession" : "PTHR11550", "name" : "CTP SYNTHASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR004468", "name" : "CTP_synthase", "description" : "CTP synthase", "type" : "FAMILY", "goXRefs" : [ { "name" : "CTP synthase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003883" }, { "name" : "pyrimidine nucleotide biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006221" } ], "pathwayXRefs" : [ { "name" : "UTP and CTP dephosphorylation II", "databaseName" : "MetaCyc", "id" : "PWY-7177" }, { "name" : "UTP and CTP dephosphorylation I", "databaseName" : "MetaCyc", "id" : "PWY-7185" }, { "name" : "Interconversion of nucleotide di- and triphosphates", "databaseName" : "Reactome", "id" : "R-HSA-499943" }, { "name" : "UTP and CTP de novo biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-7176" }, { "name" : "Pyrimidine metabolism", "databaseName" : "KEGG", "id" : "00240+6.3.4.2" } ] } }, "locations" : [ { "start" : 1, "end" : 570, "hmmStart" : 1, "hmmEnd" : 558, "hmmLength" : 586, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 575, "location-fragments" : [ { "start" : 1, "end" : 570, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-242, "familyName" : "CTP SYNTHASE 2", "score" : 808.2, "model-ac" : "PTHR11550" } ], "xref" : [ { "name" : "XP_018910266.1 PREDICTED: CTP synthase-like [Bemisia tabaci]", "id" : "XP_018910266.1" } ] },{ "sequence" : "MALVQKPDTEVIEKTDTNTTEAQIVKHPLQHTWTLWYFENDRSRKWEENQREVIDFNTVEDFWCLFNHIKPAGELKNSSDYSLFKKGIRPMWEDDANKNGGRWLINIDKPTRDEINLCWLELVLCMIGEAFDEASDEICGAVVSIRAKAAKLGLWTGNANNEKAVKYIGYKLKESLKLQPKVLIYQTHKDTVNHGSTIRSTYQI", "md5" : "ee081fe0a999ec35c622cd3add47221b", "matches" : [ { "signature" : { "accession" : "PF01652", "name" : "IF4E", "description" : "Eukaryotic initiation factor 4E", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001040", "name" : "TIF_eIF_4E", "description" : "Translation Initiation factor eIF- 4e", "type" : "FAMILY", "goXRefs" : [ { "name" : "translation initiation factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003743" }, { "name" : "translational initiation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006413" }, { "name" : "RNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003723" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 28, "end" : 182, "hmmStart" : 1, "hmmEnd" : 155, "hmmLength" : 159, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.1E-56, "score" : 188.6, "envelopeStart" : 28, "envelopeEnd" : 186, "postProcessed" : true, "location-fragments" : [ { "start" : 28, "end" : 182, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-56, "score" : 188.9, "model-ac" : "PF01652" }, { "signature" : { "accession" : "G3DSA:3.30.760.10", "name" : "RNA Cap", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR023398", "name" : "TIF_eIF4e-like", "description" : "Translation Initiation factor eIF- 4e-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 18, "end" : 204, "hmmStart" : 6, "hmmEnd" : 187, "hmmLength" : 191, "hmmBounds" : "COMPLETE", "evalue" : 9.1E-69, "score" : 232.7, "envelopeStart" : 18, "envelopeEnd" : 204, "postProcessed" : true, "location-fragments" : [ { "start" : 18, "end" : 204, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.5E-69, "score" : 233.0, "model-ac" : "4tpwB00" }, { "signature" : { "accession" : "PTHR11960:SF3", "name" : "EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 1B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 196, "hmmStart" : 36, "hmmEnd" : 220, "hmmLength" : 229, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 202, "location-fragments" : [ { "start" : 14, "end" : 196, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-69, "familyName" : "EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 1B", "score" : 234.8, "model-ac" : "PTHR11960:SF3" }, { "signature" : { "accession" : "SSF55418", "name" : "eIF4e-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR023398", "name" : "TIF_eIF4e-like", "description" : "Translation Initiation factor eIF- 4e-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 15, "end" : 199, "hmmLength" : 213, "location-fragments" : [ { "start" : 15, "end" : 199, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.62E-67, "model-ac" : "0049154" }, { "signature" : { "accession" : "PS00813", "name" : "IF4E", "description" : "Eukaryotic initiation factor 4E signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019770", "name" : "TIF_eIF_4E_CS", "description" : "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "RNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003723" }, { "name" : "translation initiation factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003743" }, { "name" : "cytoplasm", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005737" }, { "name" : "translational initiation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006413" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 80, "end" : 103, "level" : "STRONG", "cigarAlignment" : "2M2I2M2I1M1I1M1I3M5I4M", "alignment" : "DYslFKkgIrPmWEDdanknGGRW", "location-fragments" : [ { "start" : 80, "end" : 103, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00813" }, { "signature" : { "accession" : "PTHR11960", "name" : "EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR001040", "name" : "TIF_eIF_4E", "description" : "Translation Initiation factor eIF- 4e", "type" : "FAMILY", "goXRefs" : [ { "name" : "translation initiation factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003743" }, { "name" : "translational initiation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006413" }, { "name" : "RNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003723" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 196, "hmmStart" : 36, "hmmEnd" : 220, "hmmLength" : 229, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 202, "location-fragments" : [ { "start" : 14, "end" : 196, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-69, "familyName" : "EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 1B", "score" : 234.8, "model-ac" : "PTHR11960" } ], "xref" : [ { "name" : "XP_018909988.1 PREDICTED: eukaryotic translation initiation factor 4E-like [Bemisia tabaci]", "id" : "XP_018909988.1" } ] },{ "sequence" : "MCSLLEPSASMAPVLLVVFLATAFHQVCMTSGDARVGRSDVREVLRGQIDPSFWPTRGRRGGSSEESEPPFWANRGREFQSEEEQPPFWGNRGRTLDQDPDTHHHSRPPVEALLAVDRDPEALIPHIQKWFNVRKRQQRLASCCDTPFSANYSMYVEEPQHILLERRGGSEEKDDQFWVSRGRREATEKRESNLERLNREFSPLYEDAEEGPSVQKRSEPPPAPKVEDPNAEDAKFWKSLASTIGAKRARPSNASDAEPQQ", "md5" : "57b6fb6078fb12e072860e3a9024a305", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 189, "end" : 214, "location-fragments" : [ { "start" : 189, "end" : 214, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 246, "end" : 261, "location-fragments" : [ { "start" : 246, "end" : 261, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 52, "end" : 108, "location-fragments" : [ { "start" : 52, "end" : 108, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 189, "end" : 261, "location-fragments" : [ { "start" : 189, "end" : 261, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910153.1 PREDICTED: uncharacterized protein LOC109039214 isoform X2 [Bemisia tabaci]", "id" : "XP_018910153.1" } ] },{ "sequence" : "MSPQSDTTKKQSREVTQKESVASSLLAGAIAGAIAKTTIAPLDRTKIYFQVNHAPYSTKKALKFMIQSYKTDGVISLWRGNSATMARIIPYAAIQFTAHDQWKHFLRVESNDKADENFLNLSSQVRRFLAGSLAGVTSQSLTYPLDLARACMAVTRKDQYASLSRVFAHLYKENGFLGLYKGYTPTILGIIPYAGASFFTYGTLKKHYIEKKGHTTFFENLCFGAVSGVCGQTTSYPLDIIRRRMQTATAIGNKHFSMRETIRNIYNLEGIRRGFFKGLSMNWIKGPVAVGVSFSTYDWASSSIKKFVVTFT", "md5" : "797041fcaa1156b55509d9b1bc513415", "matches" : [ { "signature" : { "accession" : "PTHR24089", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 302, "hmmStart" : 85, "hmmEnd" : 366, "hmmLength" : 374, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 309, "location-fragments" : [ { "start" : 15, "end" : 302, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-116, "familyName" : "MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A42", "score" : 391.6, "model-ac" : "PTHR24089" }, { "signature" : { "accession" : "G3DSA:1.50.40.10", "name" : "Mitochondrial carrier domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR023395", "name" : "Mt_carrier_dom_sf", "description" : "Mitochondrial carrier domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 307, "hmmStart" : 5, "hmmEnd" : 294, "hmmLength" : 304, "hmmBounds" : "COMPLETE", "evalue" : 2.0E-82, "score" : 278.2, "envelopeStart" : 14, "envelopeEnd" : 307, "postProcessed" : true, "location-fragments" : [ { "start" : 14, "end" : 307, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-82, "score" : 278.5, "model-ac" : "4c9qA00" }, { "signature" : { "accession" : "SSF103506", "name" : "Mitochondrial carrier", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR023395", "name" : "Mt_carrier_dom_sf", "description" : "Mitochondrial carrier domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 19, "end" : 299, "hmmLength" : 292, "location-fragments" : [ { "start" : 19, "end" : 299, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.45E-72, "model-ac" : "0048588" }, { "signature" : { "accession" : "PR00928", "name" : "GRAVESDC", "description" : "Graves disease carrier protein signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002167", "name" : "Graves_DC", "description" : "Graves disease carrier protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "mitochondrial inner membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005743" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 16, "end" : 36, "pvalue" : 0.0037, "score" : 42.86, "motifNumber" : 1, "location-fragments" : [ { "start" : 16, "end" : 36, "dc-status" : "CONTINUOUS" } ] }, { "start" : 41, "end" : 61, "pvalue" : 0.00134, "score" : 33.33, "motifNumber" : 2, "location-fragments" : [ { "start" : 41, "end" : 61, "dc-status" : "CONTINUOUS" } ] }, { "start" : 266, "end" : 286, "pvalue" : 1.76E-7, "score" : 47.62, "motifNumber" : 6, "location-fragments" : [ { "start" : 266, "end" : 286, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-6, "graphscan" : "II...I", "model-ac" : "PR00928" }, { "signature" : { "accession" : "PS50920", "name" : "SOLCAR", "description" : "Solute carrier (Solcar) repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR018108", "name" : "Mitochondrial_sb/sol_carrier", "description" : "Mitochondrial substrate/solute carrier", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 122, "end" : 207, "score" : 21.333, "alignment" : "SSQVRRFLAGSLAGVTSQSLTYPLDLARACMAV-----TRKDQYASLSRVFAHLYKENGFLGLYKGYTPTILGIIPYAGASFFTYGTLKKH", "location-fragments" : [ { "start" : 122, "end" : 207, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50920" }, { "signature" : { "accession" : "PS50920", "name" : "SOLCAR", "description" : "Solute carrier (Solcar) repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR018108", "name" : "Mitochondrial_sb/sol_carrier", "description" : "Mitochondrial substrate/solute carrier", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 215, "end" : 303, "score" : 11.25, "alignment" : "TTFFENLCFGAVSGVCGQTTSYPLDIIRRRMQT---ATAIGNKHFSMRETIRNIYNLEGIRrGFFKGLSMNWIKGPVAVGVSFSTYDWASSS", "location-fragments" : [ { "start" : 215, "end" : 303, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50920" }, { "signature" : { "accession" : "PTHR24089:SF621", "name" : "MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A42", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 302, "hmmStart" : 85, "hmmEnd" : 366, "hmmLength" : 374, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 309, "location-fragments" : [ { "start" : 15, "end" : 302, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-116, "familyName" : "MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A42", "score" : 391.6, "model-ac" : "PTHR24089:SF621" }, { "signature" : { "accession" : "PF00153", "name" : "Mito_carr", "description" : "Mitochondrial carrier protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018108", "name" : "Mitochondrial_sb/sol_carrier", "description" : "Mitochondrial substrate/solute carrier", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 18, "end" : 107, "hmmStart" : 2, "hmmEnd" : 94, "hmmLength" : 97, "hmmBounds" : "INCOMPLETE", "evalue" : 6.4E-21, "score" : 74.1, "envelopeStart" : 17, "envelopeEnd" : 110, "postProcessed" : true, "location-fragments" : [ { "start" : 18, "end" : 107, "dc-status" : "CONTINUOUS" } ] }, { "start" : 214, "end" : 305, "hmmStart" : 2, "hmmEnd" : 94, "hmmLength" : 97, "hmmBounds" : "INCOMPLETE", "evalue" : 4.1E-19, "score" : 68.3, "envelopeStart" : 213, "envelopeEnd" : 308, "postProcessed" : true, "location-fragments" : [ { "start" : 214, "end" : 305, "dc-status" : "CONTINUOUS" } ] }, { "start" : 125, "end" : 211, "hmmStart" : 6, "hmmEnd" : 96, "hmmLength" : 97, "hmmBounds" : "INCOMPLETE", "evalue" : 1.3E-22, "score" : 79.5, "envelopeStart" : 121, "envelopeEnd" : 212, "postProcessed" : true, "location-fragments" : [ { "start" : 125, "end" : 211, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-66, "score" : 220.4, "model-ac" : "PF00153" }, { "signature" : { "accession" : "PS50920", "name" : "SOLCAR", "description" : "Solute carrier (Solcar) repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR018108", "name" : "Mitochondrial_sb/sol_carrier", "description" : "Mitochondrial substrate/solute carrier", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 19, "end" : 105, "score" : 20.711, "alignment" : "ESVASSLLAGAIAGAIAKTTIAPLDRTKIYFQVN----HAPYSTKKALKFMIQSYKTDGVISLWRGNSATMARIIPYAAIQFTAHDQWKHF", "location-fragments" : [ { "start" : 19, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50920" }, { "signature" : { "accession" : "PR00926", "name" : "MITOCARRIER", "description" : "Mitochondrial carrier protein signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002067", "name" : "Mit_carrier", "description" : "Mitochondrial carrier protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "ATP transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005347" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 51, "pvalue" : 8.08E-7, "score" : 46.56, "motifNumber" : 2, "location-fragments" : [ { "start" : 37, "end" : 51, "dc-status" : "CONTINUOUS" } ] }, { "start" : 80, "end" : 100, "pvalue" : 9.98E-7, "score" : 38.95, "motifNumber" : 3, "location-fragments" : [ { "start" : 80, "end" : 100, "dc-status" : "CONTINUOUS" } ] }, { "start" : 180, "end" : 198, "pvalue" : 9.08E-9, "score" : 44.95, "motifNumber" : 5, "location-fragments" : [ { "start" : 180, "end" : 198, "dc-status" : "CONTINUOUS" } ] }, { "start" : 137, "end" : 155, "pvalue" : 8.21E-6, "score" : 40.47, "motifNumber" : 4, "location-fragments" : [ { "start" : 137, "end" : 155, "dc-status" : "CONTINUOUS" } ] }, { "start" : 224, "end" : 246, "pvalue" : 3.28E-9, "score" : 43.26, "motifNumber" : 6, "location-fragments" : [ { "start" : 224, "end" : 246, "dc-status" : "CONTINUOUS" } ] }, { "start" : 24, "end" : 37, "pvalue" : 7.61E-7, "score" : 48.01, "motifNumber" : 1, "location-fragments" : [ { "start" : 24, "end" : 37, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-34, "graphscan" : "IIIIII", "model-ac" : "PR00926" } ], "xref" : [ { "name" : "XP_018910158.1 PREDICTED: mitochondrial coenzyme A transporter SLC25A42 [Bemisia tabaci]", "id" : "XP_018910158.1" }, { "name" : "XP_018910159.1 PREDICTED: mitochondrial coenzyme A transporter SLC25A42 [Bemisia tabaci]", "id" : "XP_018910159.1" }, { "name" : "XP_018910155.1 PREDICTED: mitochondrial coenzyme A transporter SLC25A42 [Bemisia tabaci]", "id" : "XP_018910155.1" }, { "name" : "XP_018910156.1 PREDICTED: mitochondrial coenzyme A transporter SLC25A42 [Bemisia tabaci]", "id" : "XP_018910156.1" } ] },{ "sequence" : "MDISYKNLEGPVAKKLDTMFGVENCLIEVYPGKVLVPPKYKDLGERIRKMTVRPDDTFLVSLPRTGSTWAQEMVWCVGNDLDFKKATEVLSSVRTPLLELTALVGNDKRPWTGMFGNSVETVENLASPRYIKTHLSLDLLPAQIETVKPKIVYVTRNPKDVCVSYFHYCRLVHELVGGTFEDFCELFLQDRVPMSPFWPHVLSFWNRRHEPNVLFLKYEDMKRDGRKAIRQVAEFLDKKLSDEEITALEDYLSFDKMKENPSVNLEPIVNLMGNVNTQEKFIRKGVVGDYKAHMNEEMIARFDKWIEENTKGTGLTFE", "md5" : "93e023f72e90c816b816e094b124fd12", "matches" : [ { "signature" : { "accession" : "PF00685", "name" : "Sulfotransfer_1", "description" : "Sulfotransferase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000863", "name" : "Sulfotransferase_dom", "description" : "Sulfotransferase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "sulfotransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008146" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 54, "end" : 314, "hmmStart" : 1, "hmmEnd" : 267, "hmmLength" : 267, "hmmBounds" : "COMPLETE", "evalue" : 3.7E-70, "score" : 236.5, "envelopeStart" : 54, "envelopeEnd" : 314, "postProcessed" : true, "location-fragments" : [ { "start" : 54, "end" : 314, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-70, "score" : 236.7, "model-ac" : "PF00685" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 31, "end" : 317, "hmmLength" : 285, "location-fragments" : [ { "start" : 31, "end" : 317, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.31E-84, "model-ac" : "0054829" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 318, "hmmStart" : 29, "hmmEnd" : 346, "hmmLength" : 351, "hmmBounds" : "COMPLETE", "evalue" : 8.4E-100, "score" : 336.4, "envelopeStart" : 7, "envelopeEnd" : 318, "postProcessed" : true, "location-fragments" : [ { "start" : 7, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-100, "score" : 336.6, "model-ac" : "1fmjA00" }, { "signature" : { "accession" : "PTHR11783:SF154", "name" : "MIP25022P1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 13, "end" : 317, "hmmStart" : 13, "hmmEnd" : 323, "hmmLength" : 326, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 318, "location-fragments" : [ { "start" : 13, "end" : 317, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-123, "familyName" : "MIP25022P1", "score" : 412.6, "model-ac" : "PTHR11783:SF154" }, { "signature" : { "accession" : "PTHR11783", "name" : "SULFOTRANSFERASE SULT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 13, "end" : 317, "hmmStart" : 13, "hmmEnd" : 323, "hmmLength" : 326, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 318, "location-fragments" : [ { "start" : 13, "end" : 317, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-123, "familyName" : "MIP25022P1", "score" : 412.6, "model-ac" : "PTHR11783" } ], "xref" : [ { "name" : "XP_018909916.1 PREDICTED: estrogen sulfotransferase [Bemisia tabaci]", "id" : "XP_018909916.1" }, { "name" : "XP_018909917.1 PREDICTED: estrogen sulfotransferase [Bemisia tabaci]", "id" : "XP_018909917.1" } ] },{ "sequence" : "MIGHSISKCPSRPKRHILQQLCLATRSVKEGCSKPPTVGLPTTSSLSSKFGSLASDHVRQSSSVLPTQAQVVICGSGVVANSVAYHLVQHGWTDVLVIDQGSICGGTSNFGSGTLGLFKPIDERHIISNSIKLYRQLQEMGHDIGLKQVGSVNLAQTKDRIIMLKRRIAYNLPTGLHCEIIGPNELQKLHPHICTDNILGGVWVPEDAVVDTLSVCRVLAKLAKQGGASYVENCIVEKISTENNCIKSVTTNRGDVDCEYFVNCAGMWARELGLKSEPKVRIPVYPAEHYYAKTTPISGISDNLPYIRDFDSHIYMREYNGGFLVGGFEPQAKPAFLGHKGVPGDWKKQLPADWDHFKPLWQNAIQRLPILKDVPEPSLMNYPDTFTPNGKWILGETPEVDNYFVAVGMNGNSLQGAGGIGKALAEWIVEGEPTQELLKFDVQRFLDLHNNRNYLQQRIQEVVGRHYSIMYPSQSEFQLARKLRCSPLYSVLEKRGAVFGMRMGYERPLYFDSSYQPGQPLPTMPPGTFFKPKFFDYLLEEYYACREGVGVIDMSSFSKIKIKMQKPPIDSGDLPWENLAQTPRNVVDWLQRLCSNDVNIPVGGIVHTGMQNERGGYENDCILVREAENSFFMVSPTSQQTRVFEWLRRHLPTDHSVSLNDVTSMYTVINVVGPKARQLLSELSNVDIDLQPFTYKKVNVGYASDVMMMSFTHTGEPGFCLYIPSEYALHVYQQLAAVGVDYGLRDVGTITQRWMRIEKFIPLWGEDLNSFTTPFECGSGYRVKLDNDYFMGKFALQKQKEQGVKKRLVLFQLEGIDPDKDVWAWGSEPIYRDSEFVGIVTSAGFGFTLGKLVCMGYIRRPGQSRRHERLDGHHNDQIVTNQFIMSTSARYEIDIAGQRVLAKPQIYAPKATSINPSSAGLETPYVPKVVISHSNNP", "md5" : "49d9a858b3a81f49066bca00536ec888", "matches" : [ { "signature" : { "accession" : "PF08669", "name" : "GCV_T_C", "description" : "Glycine cleavage T-protein C-terminal barrel domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013977", "name" : "GCV_T_C", "description" : "Glycine cleavage T-protein, C-terminal barrel domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "One carbon pool by folate", "databaseName" : "KEGG", "id" : "00670+2.1.2.10" }, { "name" : "Glycine, serine and threonine metabolism", "databaseName" : "KEGG", "id" : "00260+2.1.2.10" } ] } }, "locations" : [ { "start" : 806, "end" : 903, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 80, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.2E-13, "score" : 49.4, "envelopeStart" : 806, "envelopeEnd" : 906, "postProcessed" : true, "location-fragments" : [ { "start" : 806, "end" : 903, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-13, "score" : 50.7, "model-ac" : "PF08669" }, { "signature" : { "accession" : "SSF103025", "name" : "Folate-binding domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 481, "end" : 804, "hmmLength" : 315, "location-fragments" : [ { "start" : 481, "end" : 804, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.73E-73, "model-ac" : "0042338" }, { "signature" : { "accession" : "PTHR13847:SF257", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 60, "end" : 866, "hmmStart" : 59, "hmmEnd" : 859, "hmmLength" : 924, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 41, "envelopeEnd" : 925, "location-fragments" : [ { "start" : 60, "end" : 866, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.4E-183, "familyName" : "", "score" : 613.2, "model-ac" : "PTHR13847:SF257" }, { "signature" : { "accession" : "G3DSA:3.30.1360.120", "name" : "Probable tRNA modification gtpase trme; domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR027266", "name" : "TrmE/GcvT_dom1", "description" : "GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 481, "end" : 771, "hmmStart" : 1, "hmmEnd" : 307, "hmmLength" : 198, "hmmBounds" : "INCOMPLETE", "evalue" : 1.0E-99, "score" : 335.3, "envelopeStart" : 481, "envelopeEnd" : 796, "postProcessed" : true, "location-fragments" : [ { "start" : 662, "end" : 771, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 481, "end" : 556, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 8.8E-101, "score" : 338.8, "model-ac" : "1pj5A03" }, { "signature" : { "accession" : "SSF101790", "name" : "Aminomethyltransferase beta-barrel domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029043", "name" : "GcvT/YgfZ_C", "description" : "Glycine cleavage T-protein/YgfZ, C-terminal", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 807, "end" : 860, "hmmLength" : 88, "location-fragments" : [ { "start" : 807, "end" : 860, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.91E-12, "model-ac" : "0042335" }, { "signature" : { "accession" : "PF16350", "name" : "FAO_M", "description" : "FAD dependent oxidoreductase central domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR032503", "name" : "FAO_M", "description" : "FAD dependent oxidoreductase, central domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 430, "end" : 486, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 56, "hmmBounds" : "COMPLETE", "evalue" : 4.1E-17, "score" : 62.2, "envelopeStart" : 430, "envelopeEnd" : 486, "postProcessed" : true, "location-fragments" : [ { "start" : 430, "end" : 486, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-17, "score" : 63.2, "model-ac" : "PF16350" }, { "signature" : { "accession" : "SSF51905", "name" : "FAD/NAD(P)-binding domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036188", "name" : "FAD/NAD-bd_sf", "description" : "FAD/NAD(P)-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 69, "end" : 472, "hmmLength" : 306, "location-fragments" : [ { "start" : 69, "end" : 282, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 388, "end" : 472, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 5.5E-48, "model-ac" : "0048771" }, { "signature" : { "accession" : "G3DSA:2.40.30.110", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 804, "end" : 903, "hmmStart" : 2, "hmmEnd" : 74, "hmmLength" : 77, "hmmBounds" : "COMPLETE", "evalue" : 2.6E-19, "score" : 70.5, "envelopeStart" : 804, "envelopeEnd" : 903, "postProcessed" : true, "location-fragments" : [ { "start" : 804, "end" : 903, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-19, "score" : 71.5, "model-ac" : "4pabA05" }, { "signature" : { "accession" : "SSF54373", "name" : "FAD-linked reductases, C-terminal domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 284, "end" : 387, "hmmLength" : 119, "location-fragments" : [ { "start" : 284, "end" : 387, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.51E-23, "model-ac" : "0042337" }, { "signature" : { "accession" : "G3DSA:3.30.70.1400", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 557, "end" : 796, "hmmStart" : 1, "hmmEnd" : 307, "hmmLength" : 120, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.0E-99, "score" : 335.3, "envelopeStart" : 481, "envelopeEnd" : 796, "postProcessed" : true, "location-fragments" : [ { "start" : 772, "end" : 796, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 557, "end" : 661, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 8.8E-101, "score" : 338.8, "model-ac" : "1pj5A04" }, { "signature" : { "accession" : "PF01571", "name" : "GCV_T", "description" : "Aminomethyltransferase folate-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006222", "name" : "GCV_T_N", "description" : "Aminomethyltransferase, folate-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 488, "end" : 780, "hmmStart" : 1, "hmmEnd" : 254, "hmmLength" : 256, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.0E-67, "score" : 225.7, "envelopeStart" : 488, "envelopeEnd" : 782, "postProcessed" : true, "location-fragments" : [ { "start" : 488, "end" : 780, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-67, "score" : 226.8, "model-ac" : "PF01571" }, { "signature" : { "accession" : "G3DSA:3.50.50.60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036188", "name" : "FAD/NAD-bd_sf", "description" : "FAD/NAD(P)-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 71, "end" : 446, "hmmStart" : 1, "hmmEnd" : 388, "hmmLength" : 243, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-113, "score" : 381.6, "envelopeStart" : 71, "envelopeEnd" : 447, "postProcessed" : true, "location-fragments" : [ { "start" : 388, "end" : 446, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 71, "end" : 147, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 207, "end" : 283, "dc-status" : "NC_TERMINAL_DISC" } ] } ], "evalue" : 1.3E-113, "score" : 382.1, "model-ac" : "1pj5A01" }, { "signature" : { "accession" : "PF01266", "name" : "DAO", "description" : "FAD dependent oxidoreductase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006076", "name" : "FAD-dep_OxRdtase", "description" : "FAD dependent oxidoreductase", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" }, { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 71, "end" : 427, "hmmStart" : 2, "hmmEnd" : 353, "hmmLength" : 353, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.1E-54, "score" : 184.9, "envelopeStart" : 70, "envelopeEnd" : 427, "postProcessed" : true, "location-fragments" : [ { "start" : 71, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-54, "score" : 185.6, "model-ac" : "PF01266" }, { "signature" : { "accession" : "G3DSA:3.30.9.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 148, "end" : 387, "hmmStart" : 1, "hmmEnd" : 388, "hmmLength" : 178, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-113, "score" : 381.6, "envelopeStart" : 71, "envelopeEnd" : 447, "postProcessed" : true, "location-fragments" : [ { "start" : 148, "end" : 206, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 284, "end" : 387, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.3E-113, "score" : 382.1, "model-ac" : "1pj5A02" }, { "signature" : { "accession" : "PTHR13847", "name" : "FAD NAD BINDING OXIDOREDUCTASES", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 60, "end" : 866, "hmmStart" : 59, "hmmEnd" : 859, "hmmLength" : 924, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 41, "envelopeEnd" : 925, "location-fragments" : [ { "start" : 60, "end" : 866, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.4E-183, "familyName" : "", "score" : 613.2, "model-ac" : "PTHR13847" } ], "xref" : [ { "name" : "XP_018910547.1 PREDICTED: pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910547.1" } ] },{ "sequence" : "MTICEKVDLSDIPVSALRPASKEKLCAMLNFNLVIPSPSGLPRDWRGLAQLLNVKPPCGYMPNPTGHILCQFEKLPNSTLDKLHKVFGELDRWDVFDDMDNIFQTDGKNYLQVVQNSPGNSSSLHIDFLTDDIVTLDDLHRAKNNQPPLIYDAFVLFAQEDEEFAQMTIDKLEKEYLAKVCYKDRDFIAGLPLEHTGVMKMLEERCHHLVVIISNSFIRSEFNKYFLNFAAAVGIEQRRVKIIPIVLEYCPDLPSVVRFCHLLDYTRSSKLYNFWDKLGQAVAQSRVSRTVLEHSTQRLMLEDIKPRSTNQEKKISQDESYSQEAKEKSLRKEEQLWNAENYFQQKASTCKSSQEPSPKSSDKKREKPGKIIKSITDAIRKLPKSKLSKKSKELACPSD", "md5" : "08fbb89c4c11de71be4a7304c18207c1", "matches" : [ { "signature" : { "accession" : "PF01582", "name" : "TIR", "description" : "TIR domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000157", "name" : "TIR_dom", "description" : "Toll/interleukin-1 receptor homology (TIR) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" }, { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 151, "end" : 281, "hmmStart" : 2, "hmmEnd" : 138, "hmmLength" : 176, "hmmBounds" : "INCOMPLETE", "evalue" : 1.7E-6, "score" : 28.0, "envelopeStart" : 150, "envelopeEnd" : 339, "postProcessed" : true, "location-fragments" : [ { "start" : 151, "end" : 281, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-6, "score" : 28.0, "model-ac" : "PF01582" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 155, "end" : 175, "location-fragments" : [ { "start" : 155, "end" : 175, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PS50104", "name" : "TIR", "description" : "TIR domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000157", "name" : "TIR_dom", "description" : "Toll/interleukin-1 receptor homology (TIR) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" }, { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 149, "end" : 252, "score" : 15.287, "alignment" : "LIYDAFVLFA--QEDEEFAQ-MTIDKLEKEYLAKVCYKDRDFIAGLPLEHTgVMKMLEErCHHLVVIISNSFIRSEFNKYFLNFAAAVGIEQRRVKIIPIVLEYCPD---------------------------------------", "location-fragments" : [ { "start" : 149, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50104" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 305, "end" : 325, "location-fragments" : [ { "start" : 305, "end" : 325, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00255", "name" : "till_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000157", "name" : "TIR_dom", "description" : "Toll/interleukin-1 receptor homology (TIR) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" }, { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 150, "end" : 285, "hmmStart" : 1, "hmmEnd" : 147, "hmmLength" : 147, "hmmBounds" : "COMPLETE", "evalue" : 0.0057, "score" : 11.6, "location-fragments" : [ { "start" : 150, "end" : 285, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0057, "score" : 11.6, "model-ac" : "SM00255" }, { "signature" : { "accession" : "G3DSA:1.10.533.10", "name" : "Death Domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 118, "hmmStart" : 2, "hmmEnd" : 101, "hmmLength" : 110, "hmmBounds" : "COMPLETE", "evalue" : 3.4E-18, "score" : 67.6, "envelopeStart" : 11, "envelopeEnd" : 118, "postProcessed" : true, "location-fragments" : [ { "start" : 11, "end" : 118, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-19, "score" : 70.9, "model-ac" : "3mopA00" }, { "signature" : { "accession" : "PTHR15079:SF3", "name" : "MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 318, "hmmStart" : 41, "hmmEnd" : 381, "hmmLength" : 469, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 392, "location-fragments" : [ { "start" : 11, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-44, "familyName" : "MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88", "score" : 152.7, "model-ac" : "PTHR15079:SF3" }, { "signature" : { "accession" : "SSF47986", "name" : "DEATH domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011029", "name" : "DEATH-like_dom_sf", "description" : "Death-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 101, "hmmLength" : 90, "location-fragments" : [ { "start" : 14, "end" : 101, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.24E-11, "model-ac" : "0050656" }, { "signature" : { "accession" : "SSF52200", "name" : "Toll/Interleukin receptor TIR domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035897", "name" : "Toll_tir_struct_dom_sf", "description" : "Toll/interleukin-1 receptor homology (TIR) domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 148, "end" : 278, "hmmLength" : 149, "location-fragments" : [ { "start" : 148, "end" : 278, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.53E-18, "model-ac" : "0046889" }, { "signature" : { "accession" : "G3DSA:3.40.50.10140", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR035897", "name" : "Toll_tir_struct_dom_sf", "description" : "Toll/interleukin-1 receptor homology (TIR) domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 151, "end" : 283, "hmmStart" : 2, "hmmEnd" : 133, "hmmLength" : 137, "hmmBounds" : "COMPLETE", "evalue" : 6.6E-25, "score" : 89.7, "envelopeStart" : 151, "envelopeEnd" : 283, "postProcessed" : true, "location-fragments" : [ { "start" : 151, "end" : 283, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-25, "score" : 90.9, "model-ac" : "4eo7A01" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 357, "end" : 393, "location-fragments" : [ { "start" : 357, "end" : 393, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR15079", "name" : "MYD88", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR017281", "name" : "Myelin_different_resp_MyD88", "description" : "Myeloid differentiation primary response protein MyD88", "type" : "FAMILY", "goXRefs" : [ { "name" : "TIR domain binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0070976" }, { "name" : "positive regulation of I-kappaB kinase/NF-kappaB signaling", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0043123" }, { "name" : "MyD88-dependent toll-like receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0002755" } ], "pathwayXRefs" : [ { "name" : "p75NTR recruits signalling complexes", "databaseName" : "Reactome", "id" : "R-HSA-209543" }, { "name" : "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling", "databaseName" : "Reactome", "id" : "R-HSA-6811558" }, { "name" : "PIP3 activates AKT signaling", "databaseName" : "Reactome", "id" : "R-HSA-1257604" }, { "name" : "IRAK4 deficiency (TLR5)", "databaseName" : "Reactome", "id" : "R-HSA-5603037" }, { "name" : "ER-Phagosome pathway", "databaseName" : "Reactome", "id" : "R-HSA-1236974" }, { "name" : "IRAK4 deficiency (TLR2/4)", "databaseName" : "Reactome", "id" : "R-HSA-5603041" }, { "name" : "DEx/H-box helicases activate type I IFN and inflammatory cytokines production", "databaseName" : "Reactome", "id" : "R-HSA-3134963" }, { "name" : "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation", "databaseName" : "Reactome", "id" : "R-HSA-975138" }, { "name" : "MyD88 deficiency (TLR2/4)", "databaseName" : "Reactome", "id" : "R-HSA-5602498" }, { "name" : "MyD88 dependent cascade initiated on endosome", "databaseName" : "Reactome", "id" : "R-HSA-975155" }, { "name" : "TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling", "databaseName" : "Reactome", "id" : "R-HSA-975110" }, { "name" : "MyD88:MAL(TIRAP) cascade initiated on plasma membrane", "databaseName" : "Reactome", "id" : "R-HSA-166058" }, { "name" : "MyD88 cascade initiated on plasma membrane", "databaseName" : "Reactome", "id" : "R-HSA-975871" }, { "name" : "Interleukin-1 signaling", "databaseName" : "Reactome", "id" : "R-HSA-9020702" }, { "name" : "MyD88 deficiency (TLR5)", "databaseName" : "Reactome", "id" : "R-HSA-5602680" }, { "name" : "RIP-mediated NFkB activation via ZBP1", "databaseName" : "Reactome", "id" : "R-HSA-1810476" } ] } }, "locations" : [ { "start" : 11, "end" : 318, "hmmStart" : 41, "hmmEnd" : 381, "hmmLength" : 469, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 392, "location-fragments" : [ { "start" : 11, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-44, "familyName" : "MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88", "score" : 152.7, "model-ac" : "PTHR15079" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 344, "end" : 399, "location-fragments" : [ { "start" : 344, "end" : 399, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909603.1 PREDICTED: myeloid differentiation primary response protein MyD88-A [Bemisia tabaci]", "id" : "XP_018909603.1" } ] },{ "sequence" : "MSAEEQFEAFKKAYKKKYASTTEELRRFDIFKQNLIVIDKLMATKRGNVVFGVGPFTDYTNVTPSMVNYKKCHRQSSESNIKPRWPTTSWEKTILETELRFCCQEWMDEMGIVKLNPVPNENQQLQPRMLNAFSKMTLSRKSSSRSSSRSSNRGDRSNRGSRSPSPAPSERSSRASERSTRSSRGQSVPPSWSPGPFVRKIVGRDPQGGPTLDWRVPAAFYPPTESQNQHGRKCGACWAFAVLGAVEILLPRVQGYITSLSKQALIDCVVTNDGCNGGDMRDAIVYMIKIGVPSAVSYPYMARNGRCKSFIGPYMKLNYYTDVPGSNQLAEHLEHSPLPSILYAPLELQHYVSGLYDSPGCTNEVSKINHAGVIVGQYTDAWIVRFSVESDWGLQGHILIAKGRCGLGLQSFEINSPFTILRRS", "md5" : "f596649c34af25eff73275c202a514a3", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 125, "end" : 208, "location-fragments" : [ { "start" : 125, "end" : 208, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd02248", "name" : "Peptidase_C1A", "description" : "Peptidase_C1A", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR039417", "name" : "Peptidase_C1A_papain-like", "description" : "Papain-like cysteine endopeptidase", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 212, "end" : 412, "sites" : [ { "description" : "S2 subsite", "numLocations" : 6, "siteLocations" : [ { "start" : 371, "end" : 371, "residue" : "A" }, { "start" : 280, "end" : 280, "residue" : "M" }, { "start" : 341, "end" : 341, "residue" : "I" }, { "start" : 279, "end" : 279, "residue" : "D" }, { "start" : 368, "end" : 368, "residue" : "I" }, { "start" : 410, "end" : 410, "residue" : "Q" } ] }, { "description" : "active site", "numLocations" : 4, "siteLocations" : [ { "start" : 370, "end" : 370, "residue" : "H" }, { "start" : 386, "end" : 386, "residue" : "F" }, { "start" : 229, "end" : 229, "residue" : "Q" }, { "start" : 237, "end" : 237, "residue" : "C" } ] } ], "evalue" : 7.08263E-47, "score" : 158.171, "location-fragments" : [ { "start" : 212, "end" : 412, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd02248" }, { "signature" : { "accession" : "G3DSA:3.90.70.10", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 106, "end" : 412, "hmmStart" : 63, "hmmEnd" : 306, "hmmLength" : 316, "hmmBounds" : "COMPLETE", "evalue" : 5.4E-45, "score" : 156.3, "envelopeStart" : 106, "envelopeEnd" : 412, "postProcessed" : true, "location-fragments" : [ { "start" : 106, "end" : 412, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1, "end" : 100, "hmmStart" : 15, "hmmEnd" : 79, "hmmLength" : 316, "hmmBounds" : "COMPLETE", "evalue" : 8.5E-9, "score" : 37.4, "envelopeStart" : 1, "envelopeEnd" : 100, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 100, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-57, "score" : 195.9, "model-ac" : "4qrvA00" }, { "signature" : { "accession" : "PF08246", "name" : "Inhibitor_I29", "description" : "Cathepsin propeptide inhibitor domain (I29)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013201", "name" : "Prot_inhib_I29", "description" : "Cathepsin propeptide inhibitor domain (I29)", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 7, "end" : 61, "hmmStart" : 1, "hmmEnd" : 55, "hmmLength" : 58, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.1E-9, "score" : 38.5, "envelopeStart" : 7, "envelopeEnd" : 62, "postProcessed" : true, "location-fragments" : [ { "start" : 7, "end" : 61, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-10, "score" : 40.7, "model-ac" : "PF08246" }, { "signature" : { "accession" : "SM00848", "name" : "Inhibitor_I29_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013201", "name" : "Prot_inhib_I29", "description" : "Cathepsin propeptide inhibitor domain (I29)", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 7, "end" : 61, "hmmStart" : 1, "hmmEnd" : 67, "hmmLength" : 67, "hmmBounds" : "COMPLETE", "evalue" : 6.8E-7, "score" : 38.9, "location-fragments" : [ { "start" : 7, "end" : 61, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-7, "score" : 38.9, "model-ac" : "SM00848" }, { "signature" : { "accession" : "PF00112", "name" : "Peptidase_C1", "description" : "Papain family cysteine protease", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 211, "end" : 407, "hmmStart" : 4, "hmmEnd" : 210, "hmmLength" : 218, "hmmBounds" : "INCOMPLETE", "evalue" : 4.9E-33, "score" : 115.1, "envelopeStart" : 209, "envelopeEnd" : 415, "postProcessed" : true, "location-fragments" : [ { "start" : 211, "end" : 407, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-33, "score" : 115.8, "model-ac" : "PF00112" }, { "signature" : { "accession" : "SSF54001", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038765", "name" : "Papain-like_cys_pep_sf", "description" : "Papain-like cysteine peptidase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5, "end" : 76, "hmmLength" : 311, "location-fragments" : [ { "start" : 5, "end" : 76, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.34E-8, "model-ac" : "0048736" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 125, "end" : 190, "location-fragments" : [ { "start" : 125, "end" : 190, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12411", "name" : "CYSTEINE PROTEASE FAMILY C1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 6, "end" : 411, "hmmStart" : 25, "hmmEnd" : 302, "hmmLength" : 328, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 419, "location-fragments" : [ { "start" : 6, "end" : 411, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.7E-39, "familyName" : "", "score" : 136.7, "model-ac" : "PTHR12411" }, { "signature" : { "accession" : "SSF54001", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038765", "name" : "Papain-like_cys_pep_sf", "description" : "Papain-like cysteine peptidase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 210, "end" : 406, "hmmLength" : 314, "location-fragments" : [ { "start" : 210, "end" : 406, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.47E-39, "model-ac" : "0053371" }, { "signature" : { "accession" : "SM00645", "name" : "pept_c1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 208, "end" : 415, "hmmStart" : 1, "hmmEnd" : 340, "hmmLength" : 340, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-24, "score" : 96.0, "location-fragments" : [ { "start" : 208, "end" : 415, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-24, "score" : 96.0, "model-ac" : "SM00645" }, { "signature" : { "accession" : "PTHR12411:SF387", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 6, "end" : 411, "hmmStart" : 25, "hmmEnd" : 302, "hmmLength" : 328, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 419, "location-fragments" : [ { "start" : 6, "end" : 411, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.7E-39, "familyName" : "", "score" : 136.7, "model-ac" : "PTHR12411:SF387" } ], "xref" : [ { "name" : "XP_018910149.1 PREDICTED: cathepsin K-like [Bemisia tabaci]", "id" : "XP_018910149.1" } ] },{ "sequence" : "MNKPEIVSVGVVWDSDRPSLEHIMAVLGTLRTSLRLSDVFNGCDAPGSPQHELVGVVTYYGKHYSTFFFHTKLRVWIYFDDATVREVGPRWEQVVEKCRRGRYQPLLLLFAVPEGTPLDTTNAPKTITRAQNKPMNGFMRSSLCKPLQPGMVPNLNSPTIIGGRRSLTPSPEKPNGMNGMNQRRAVTPNPDQTQDKPKIMNDYQNLSLIQVSINKPPDSPTRCSLNSYGMQSPAHKRNEIVRRDSGNWSGDRNSASSSSSTSLENPYLYIVNKMQLRGSNGVPRSPTSIKPGELSSSSTGSGGVCDPGYDSYSLSSTDSLPLQQSLKHNLQLAQIPEGHQTPINGVGAYANGLPNSIDDCERLCAEADQLLGRSEEAPDLETALSLANAAAGKARAAMDAPYSNPQTASFARMKHNSCIMRARSLHRKLEEPLNTKHGEGRHSREGSGISTRGSSHSRQNSADKSNIHHSRQNSRELLASTPALSPSQLSTKLDRHIESKLPSTNERSGPNKNIEIYATLPKSKKGLLSRSSSNGSTNKSGHIMEDEEYVYDRPGRSLYSSRSKSGKKEMEKRARSEERNSKKQQEFVSNSLPKEKDSKAKKAEKKAEAKAKQEETKEAGKKQHKIRRKLLMGGLIKRKNRSMPDLRDDEIAAKEPSAISTGSLKIMAKDDSVVGKHSKLDKDSSSGLSDYLSEGHLEYSANPNLERSKLMRKSFHSSKLIHFAKVPPPPPLRTTSQLSKTDQPQYPLPNNQNHLKEHKNWNNEPLSLPFMTHYGEKPKTDSITYANGGILLHNYPQTNTLVTKALVHQEQHTSPVKTPDIDVVDGMIVNKVEDVATAFPLPPYPSPLVSATHSRQASEEFPPPPPSVVPLAEDNGGFDEPESSLLLELRQKRQQILTESVERDVTEAVAITKSLGGGDTWLKELQAKQAALRGKTLLKNSPVITNLNDATSRLPTQTDVSTIKAASPVQQPAVDEQCSLVKDLKSKFEQIKIPRTDSEPIRSVSSPCESPATLGQNPGPSPNFEQIEKAPYPTKSIIDLDPKRRSGKKKNVTFCEQVVLVATADDDEVDSFIPNPILERVLRSVLHKDSPAIDVSRDVKSVVPLKRTDSCNKYEQSLSLRNSSSTNIDDQPSTQSNDETPSQPLTKAVSDQIANANAQSQNPSPVASQIVSHSSVYQHATKVQHSPLFNRPMTANAYQQVPVSNSQRVSQPLPSPSYQSNQPAASAHAYQANETPSPQYTHSQVSQQHRASTQPTTHQHSSQYSHQLNSHSHPIQYSSHQQAQSQVSNQQSPQTQTNHHQHHPQSPSTSQYSPSHPSHPHSSSQSPYQHVPAPAQQNSSPHLPPTGPPLTSPYQPIPSSPHHSQSHPPTSPYQQVPSQHSPSPHLSQSPSHLSQSPYQQVPNLQSNNPYQKHGPNNAQHSSSYHGSHHSSPQTNMPNQQLSNSNHYDQHVNSHSPYQQVPYANGSSSETHSHPSSMSHSTSYQSLPSQSSSNHSNQSSISSSVYQHVPHPQQSSPSYHSTNGNQQFHSNERPNSSPYQHIPQSSPASQQYQKSTLGMSPSAYQSVPSHSPSQSSDQGQSNHLPNHNPHASMNGHQHSNPGRPYDPRTNNFSQSSGNLAHPDIRGQSDRFSTHHGQAAIHSSYQQNSLKMQSRHQPIARTTIAPPSQQMLSRNQRVQGIYQQDPPEYQHPPSPRISIPNGNHIPNGNHIPNGHVPNSNHLPNGNHLPNGAHIPNGHIPNGGHMGKDGDTQSEVYQRIPLNAQAQMKQRQLIDHHNSVNQQLSYGPGKYPVPQHVPNTTKVIENGTVKGSPQGLAHLRTIQCNLCRKKDIIPPAVYCADCDFYMSRFKPKA", "md5" : "c0cee921f299a514d92daed0b51930fd", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 423, "end" : 446, "location-fragments" : [ { "start" : 423, "end" : 446, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1187, "end" : 1653, "location-fragments" : [ { "start" : 1187, "end" : 1653, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 168, "end" : 195, "location-fragments" : [ { "start" : 168, "end" : 195, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 216, "end" : 233, "location-fragments" : [ { "start" : 216, "end" : 233, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1357, "end" : 1621, "location-fragments" : [ { "start" : 1357, "end" : 1621, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50235", "name" : "USP_3", "description" : "Ubiquitin specific protease (USP) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR028889", "name" : "USP_dom", "description" : "Ubiquitin specific protease domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 113, "score" : 10.234, "alignment" : "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNKPEIVSVGVVWDSDRPSLEHIMAVLGTLRTSLRLSDVFNG----CDAPGSPQHELVGVVTYYGK----HYSTFFFHTKLRVWIYFDDATVREVGPRweqvvekcRRGRYQPLLLLFAVP", "location-fragments" : [ { "start" : 1, "end" : 113, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50235" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1694, "end" : 1724, "location-fragments" : [ { "start" : 1694, "end" : 1724, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 995, "end" : 1023, "location-fragments" : [ { "start" : 995, "end" : 1023, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR22975:SF9", "name" : "ECHINUS SPLICE FORM 3", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 615, "hmmStart" : 269, "hmmEnd" : 915, "hmmLength" : 1267, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 633, "location-fragments" : [ { "start" : 1, "end" : 615, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-60, "familyName" : "ECHINUS SPLICE FORM 3", "score" : 208.6, "model-ac" : "PTHR22975:SF9" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 447, "end" : 461, "location-fragments" : [ { "start" : 447, "end" : 461, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1338, "end" : 1356, "location-fragments" : [ { "start" : 1338, "end" : 1356, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 525, "end" : 540, "location-fragments" : [ { "start" : 525, "end" : 540, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 595, "end" : 619, "location-fragments" : [ { "start" : 595, "end" : 619, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 562, "end" : 621, "location-fragments" : [ { "start" : 562, "end" : 621, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR22975", "name" : "UBIQUITIN SPECIFIC PROTEINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 615, "hmmStart" : 269, "hmmEnd" : 915, "hmmLength" : 1267, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 633, "location-fragments" : [ { "start" : 1, "end" : 615, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-60, "familyName" : "ECHINUS SPLICE FORM 3", "score" : 208.6, "model-ac" : "PTHR22975" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1630, "end" : 1653, "location-fragments" : [ { "start" : 1630, "end" : 1653, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 216, "end" : 260, "location-fragments" : [ { "start" : 216, "end" : 260, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF54001", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038765", "name" : "Papain-like_cys_pep_sf", "description" : "Papain-like cysteine peptidase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 33, "end" : 111, "hmmLength" : 347, "location-fragments" : [ { "start" : 33, "end" : 111, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.16E-5, "model-ac" : "0041295" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 422, "end" : 642, "location-fragments" : [ { "start" : 422, "end" : 642, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 278, "end" : 302, "location-fragments" : [ { "start" : 278, "end" : 302, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1676, "end" : 1753, "location-fragments" : [ { "start" : 1676, "end" : 1753, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 472, "end" : 492, "location-fragments" : [ { "start" : 472, "end" : 492, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1187, "end" : 1337, "location-fragments" : [ { "start" : 1187, "end" : 1337, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 999, "end" : 1023, "location-fragments" : [ { "start" : 999, "end" : 1023, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1114, "end" : 1173, "location-fragments" : [ { "start" : 1114, "end" : 1173, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 171, "end" : 195, "location-fragments" : [ { "start" : 171, "end" : 195, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910183.1 PREDICTED: histone-lysine N-methyltransferase, H3 lysine-79 specific-like isoform X3 [Bemisia tabaci]", "id" : "XP_018910183.1" } ] },{ "sequence" : "MLKTFFEHELGENHLAKDPQKTHKLGLFRDKSIFSNGTQFWKHFARYPVIYLDLGSVKTKTFHDFTTSFIEHCVHPLMEKFSYLLNNTNIWESSALKTVSFSKSYKWKKEELIKFGVNLAELVRRHHDTKSILLIDDYDHPVISAVLDTHVSQDDTINIIEFMGAFVNAMTKHSDHIYRSVLTGTIAVTLEYDMDTSSSNVEYYSIFDARIFYNAYGLTGDDLKVLQKQLHVPPSQMELTRSYYQGYNVFDNRFAADTGLYIRWAPVAPKTKIYNTYSVLASLKNVDLKPWWPSGEVPLIPLITADKYATDFEECMLRSCSIDVETYISRFDLLQLKKSLLTPEKPTVTSDIILAFLFQSGYFTPLERNGDERTITAPNYEVQTKMIESFYRTAYLYKRYNYTKEDEKQYVTAMDKLNSTISTFQDVVKSVRNLFRSEAPLGEKFMQAVLLYPLVNSDKFYAYRIEKHDDPFLRYDAVAERRRDNAAIVVTLRCRPQDLKRAVGQIVKAPVGNKFDLLPNRKDKIDLRFIITQDKEVYGYFNYTTSKGDSTSELWPTLKHY", "md5" : "b8f32d3412e8b0c7f32311fd31221b5c", "matches" : [ { "signature" : { "accession" : "PF09820", "name" : "AAA-ATPase_like", "description" : "Predicted AAA-ATPase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018631", "name" : "AAA-ATPase-like_dom", "description" : "AAA-ATPase-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 23, "end" : 249, "hmmStart" : 57, "hmmEnd" : 259, "hmmLength" : 279, "hmmBounds" : "INCOMPLETE", "evalue" : 1.9E-13, "score" : 50.5, "envelopeStart" : 1, "envelopeEnd" : 285, "postProcessed" : true, "location-fragments" : [ { "start" : 23, "end" : 249, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-14, "score" : 51.6, "model-ac" : "PF09820" }, { "signature" : { "accession" : "PTHR34825", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 517, "hmmStart" : 80, "hmmEnd" : 580, "hmmLength" : 590, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 526, "location-fragments" : [ { "start" : 1, "end" : 517, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-52, "familyName" : "FAMILY NOT NAMED", "score" : 180.8, "model-ac" : "PTHR34825" } ], "xref" : [ { "name" : "XP_018909811.1 PREDICTED: uncharacterized protein LOC109038977 isoform X4 [Bemisia tabaci]", "id" : "XP_018909811.1" } ] },{ "sequence" : "MFKKSAMNCRIILYLYFLCIISLLVSLCLFLNSSKHNYQNGHKKQPDFLVRRDPEAAHENEVFILSKANIGQFVWHHVLNASSYFIRHRMWQMGSLDFDGVSYKFYAGPGLIQTTAPKQIERLILILNGRTESKVASSKLWLDYLSVFKNLQKVGVVLLGNENCDNNWILPYLESNGGPVTFVFLVYDSPLVNNQDVFQWPLGVADYRGFPNVNPSDVDIILKRPFICNFMGTVYEDSSRKFLMDILQSSPLNRSIYLKGRDKWTEGESTESIKNYLNALKNSDYTLNPVGLNSECYRIYEAMSVGSTPVIENVVTPGSCSRGKDSPLRLLKKYNAPVVYVNDWSNIMDIIRDQLNISQQDLMNQRIRILNWYTEFKRKMKHQFHRVVKSKFAIANSAFI", "md5" : "751a3756527e1c7eef83df007918e4da", "matches" : [ { "signature" : { "accession" : "PTHR15576", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 51, "end" : 393, "hmmStart" : 72, "hmmEnd" : 415, "hmmLength" : 420, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 397, "location-fragments" : [ { "start" : 51, "end" : 393, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-118, "familyName" : "FAMILY NOT NAMED", "score" : 398.7, "model-ac" : "PTHR15576" } ], "xref" : [ { "name" : "XP_018910514.1 PREDICTED: transmembrane protein 5-like [Bemisia tabaci]", "id" : "XP_018910514.1" } ] },{ "sequence" : "MACKIVLLGIIGVAASTTHRKVMIRMPKQMKNTEMKEAMSNDPQMPTMSQPKDQSPEQSRVAVGNEDTGKGKGEYFMDVYSLETGPEQLEFGHVLEDPNEWEQRYERKDHENNRFQGKVRWGDKRGSYGEHYWDFNHGGHDKEQPGMASESQKEPQMMKMSETKRSHDYAMPQPSTKNHRMNQRAATVKPDVNERVKRHKKIQLPKLVFDTETWTVIDENTDQHFFLQPIVNP", "md5" : "f296e85abe3a86e2be443bd2de31a3e0", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 62, "location-fragments" : [ { "start" : 35, "end" : 62, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 70, "location-fragments" : [ { "start" : 35, "end" : 70, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910453.1 PREDICTED: uncharacterized protein LOC109039434 isoform X2 [Bemisia tabaci]", "id" : "XP_018910453.1" } ] },{ "sequence" : "MKDKPIGGRTTGYRKKALFQITKVLWHLDIFRRSFRELSGHTCMAESCIFCALKELFSQLQSSHENALPPDALRRALAESFFDQQRFQLGFMDDAAECFENMLLRIHYHLACNESEDMCRALHCIPHRKFAMTLVEQSVCGSCGATSEPLPFTQMVHYVSASALTAQAKQTAMPSHPDLFGQLLKKAGGMGDIRDCPSACGAKIQIQRTLMNKPEIVSVGVVWDSDRPSLEHIMAVLGTLRTSLRLSDVFNGCDAPGSPQHELVGVVTYYGKHYSTFFFHTKLRVWIYFDDATVREVGPRWEQVVEKCRRGRYQPLLLLFAVPEGTPLDTTNAPKTITRAQNKPMNGFMRSSLCKPLQPGMVPNLNSPTIIGGRRSLTPSPEKPNGMNGMNQRRAVTPNPDQTQDKPKIMNDYQNLSLIQVSINKPPDSPTRCSLNSYGMQSPAHKRNEIVRRDSGNWSGDRNSASSSSSTSLENPYLYIVNKMQLRGSNGVPRSPTSIKPGELSSSSTGSGGVCDPGYDSYSLSSTDSLPLQQSLKHNLQLAQIPEGHQTPINGVGAYANGLPNSIDDCERLCAEADQLLGRSEEAPDLETALSLANAAAGKARAAMDAPYSNPQTASFARMKHNSCIMRARSLHRKLEEPLNTKHGEGRHSREGSGISTRGSSHSRQNSADKSNIHHSRQNSRELLASTPALSPSQLSTKLDRHIESKLPSTNERSGPNKNIEIYATLPKSKKGLLSRSSSNGSTNKSGHIMEDEEYVYDRPGRSLYSSRSKSGKKEMEKRARSEERNSKKQQEFVSNSLPKEKDSKAKKAEKKAEAKAKQEETKEAGKKQHKIRRKLLMGGLIKRKNRSMPDLRDDEIAAKEPSAISTGSLKIMAKDDSVVGKHSKLDKDSSSGLSDYLSEGHLEYSANPNLERSKLMRKSFHSSKLIHFAKVPPPPPLRTTSQLSKTDQPQYPLPNNQNHLKEHKNWNNEPLSLPFMTHYGEKPKTDSITYANGGILLHNYPQTNTLVTKALVHQEQHTSPVKTPDIDVVDGMIVNKVEDVATAFPLPPYPSPLVSATHSRQASEEFPPPPPSVVPLAEDNGGFDEPESSLLLELRQKRQQILTESVERDVTEAVAITKSLGGGDTWLKELQAKQAALRGKTLLKNSPVITNLNDATSRLPTQTDVSTIKAASPVQQPAVDEQCSLVKDLKSKFEQIKIPRTDSEPIRSVSSPCESPATLGQNPGPSPNFEQIEKAPYPTKSIIDLDPKRRSGKKKNVTFCEQVVLVATADDDEVDSFIPNPILERVLRSVLHKDSPAIDVSRDVKSVVPLKRTDSCNKYEQSLSLRNSSSTNIDDQPSTQSNDETPSQPLTKAVSDQIANANAQSQNPSPVASQIVSHSSVYQHATKVQHSPLFNRPMTANAYQQVPVSNSQRVSQPLPSPSYQSNQPAASAHAYQANETPSPQYTHSQVSQQHRASTQPTTHQHSSQYSHQLNSHSHPIQYSSHQQAQSQVSNQQSPQTQTNHHQHHPQSPSTSQYSPSHPSHPHSSSQSPYQHVPAPAQQNSSPHLPPTGPPLTSPYQPIPSSPHHSQSHPPTSPYQQVPSQHSPSPHLSQSPSHLSQSPYQQVPNLQSNNPYQKHGPNNAQHSSSYHGSHHSSPQTNMPNQQLSNSNHYDQHVNSHSPYQQVPYANGSSSETHSHPSSMSHSTSYQSLPSQSSSNHSNQSSISSSVYQHVPHPQQSSPSYHSTNGNQQFHSNERPNSSPYQHIPQSSPASQQYQKSTLGMSPSAYQSVPSHSPSQSSDQGQSNHLPNHNPHASMNGHQHSNPGRPYDPRTNNFSQSSGNLAHPDIRGQSDRFSTHHGQAAIHSSYQQNSLKMQSRHQPIARTTIAPPSQQMLSRNQRVQGIYQQDPPEYQHPPSPRISIPNGNHIPNGNHIPNGHVPNSNHLPNGNHLPNGAHIPNGHIPNGGHMGKDGDTQSEVYQRIPLNAQAQMKQRQLIDHHNSVNQQLSYGPGKYPVPQHVPNTTKVIENGTVKGSPQGLAHLRTIQCNLCRKKDIIPPAVYCADCDFYMSRFKPKA", "md5" : "238365e3979f86abbdad050d4344d10b", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1397, "end" : 1863, "location-fragments" : [ { "start" : 1397, "end" : 1863, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 657, "end" : 671, "location-fragments" : [ { "start" : 657, "end" : 671, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 633, "end" : 656, "location-fragments" : [ { "start" : 633, "end" : 656, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1567, "end" : 1831, "location-fragments" : [ { "start" : 1567, "end" : 1831, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1397, "end" : 1547, "location-fragments" : [ { "start" : 1397, "end" : 1547, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 682, "end" : 702, "location-fragments" : [ { "start" : 682, "end" : 702, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1324, "end" : 1383, "location-fragments" : [ { "start" : 1324, "end" : 1383, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 488, "end" : 512, "location-fragments" : [ { "start" : 488, "end" : 512, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd02257", "name" : "Peptidase_C19", "description" : "Peptidase_C19", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 81, "end" : 320, "sites" : [ ], "evalue" : 2.14367E-7, "score" : 52.1002, "location-fragments" : [ { "start" : 81, "end" : 320, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd02257" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 426, "end" : 470, "location-fragments" : [ { "start" : 426, "end" : 470, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1840, "end" : 1863, "location-fragments" : [ { "start" : 1840, "end" : 1863, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1209, "end" : 1233, "location-fragments" : [ { "start" : 1209, "end" : 1233, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 805, "end" : 829, "location-fragments" : [ { "start" : 805, "end" : 829, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR22975", "name" : "UBIQUITIN SPECIFIC PROTEINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 830, "hmmStart" : 71, "hmmEnd" : 912, "hmmLength" : 1267, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 952, "location-fragments" : [ { "start" : 24, "end" : 830, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-148, "familyName" : "ECHINUS SPLICE FORM 3", "score" : 500.2, "model-ac" : "PTHR22975" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 381, "end" : 405, "location-fragments" : [ { "start" : 381, "end" : 405, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 632, "end" : 852, "location-fragments" : [ { "start" : 632, "end" : 852, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1548, "end" : 1566, "location-fragments" : [ { "start" : 1548, "end" : 1566, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1886, "end" : 1963, "location-fragments" : [ { "start" : 1886, "end" : 1963, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 735, "end" : 750, "location-fragments" : [ { "start" : 735, "end" : 750, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR22975:SF9", "name" : "ECHINUS SPLICE FORM 3", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 830, "hmmStart" : 71, "hmmEnd" : 912, "hmmLength" : 1267, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 952, "location-fragments" : [ { "start" : 24, "end" : 830, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-148, "familyName" : "ECHINUS SPLICE FORM 3", "score" : 500.2, "model-ac" : "PTHR22975:SF9" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1205, "end" : 1233, "location-fragments" : [ { "start" : 1205, "end" : 1233, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.90.70.10", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 20, "end" : 322, "hmmStart" : 55, "hmmEnd" : 374, "hmmLength" : 404, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-19, "score" : 72.3, "envelopeStart" : 20, "envelopeEnd" : 322, "postProcessed" : true, "location-fragments" : [ { "start" : 20, "end" : 322, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-19, "score" : 72.3, "model-ac" : "4czwA01" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1904, "end" : 1934, "location-fragments" : [ { "start" : 1904, "end" : 1934, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF54001", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038765", "name" : "Papain-like_cys_pep_sf", "description" : "Papain-like cysteine peptidase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 24, "end" : 321, "hmmLength" : 347, "location-fragments" : [ { "start" : 24, "end" : 321, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.46E-22, "model-ac" : "0041295" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 378, "end" : 405, "location-fragments" : [ { "start" : 378, "end" : 405, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 772, "end" : 831, "location-fragments" : [ { "start" : 772, "end" : 831, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50235", "name" : "USP_3", "description" : "Ubiquitin specific protease (USP) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR028889", "name" : "USP_dom", "description" : "Ubiquitin specific protease domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 323, "score" : 16.743, "alignment" : "IGGRTTgYRKKALFQITKVLWHLDIFRRSFReLSGHTCMAESCIFCALKELFSQLQSSHENALPPDALRRALAESFFDQqrfQLGFMDDAAECFENMLLRIHYHL----------------ACNESEDMCRALHCIPHRKFAMTLVEQSVCGSCGATseplpFTQMVHYVSASALTAQAKQTAMPSHPDLFGQLLKKAGGMGDIRD-----CpSACGAKIQ--IQRTLMNKPEIVSVGVVWDSDRPSLEHIMAVLGTLRTSLRLSDVFNG----CDAPGSPQHELVGVVTYYGK----HYSTFFFHTKLRVWIYFDDATVREVGPRweqvvekcRRGRYQPLLLLFAVP", "location-fragments" : [ { "start" : 6, "end" : 323, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50235" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 426, "end" : 443, "location-fragments" : [ { "start" : 426, "end" : 443, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910182.1 PREDICTED: histone-lysine N-methyltransferase, H3 lysine-79 specific-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910182.1" } ] },{ "sequence" : "MDDPLFYEVQGLLNIMNRKECILLVVSRKYVTPFTVKRDESFWRDEMLGKIVKFYEGTLAPKLSADMLPRIRNLQVAAYIAYGAISELDGEKALDIYRRTQDGSEAYDVLWDESRIRIMPQHYHLVMHPNISTKEKVNQILKGYYTSRERWNWQQSSRKSFLNRYIDMHPEWTIKEDGGLTIDPAFPYLATFPTAYGYGSLQDQPQSPPKRQPSSPPKRKPLKRPSSRGQAVLALEAPQPPEVPKNDFKSKSTSGSKVDVDEAGSSPPRTKTRLQVIYEVVAFIPSVADAYQLNDLYVDKGRTLLKRDSRSYYKVQGSMAISRVRRCLFILGKLGTKEKEILHSEVVDFDAKVWRKLQQKLAHFYFSTYLVYHANPEFFKSLARGKTLRDLIAEDPFPTAEEVEAIAKDAKDDKKEEDVRD", "md5" : "98199fb326c19272f4e307bb28cb3b42", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 246, "end" : 260, "location-fragments" : [ { "start" : 246, "end" : 260, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 199, "end" : 266, "location-fragments" : [ { "start" : 199, "end" : 266, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.90.320.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011604", "name" : "Exonuc_phg/RecB_C", "description" : "Exonuclease, phage-type/RecB, C-terminal", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 264, "end" : 375, "hmmStart" : 127, "hmmEnd" : 189, "hmmLength" : 216, "hmmBounds" : "COMPLETE", "evalue" : 3.4E-6, "score" : 28.7, "envelopeStart" : 264, "envelopeEnd" : 375, "postProcessed" : true, "location-fragments" : [ { "start" : 264, "end" : 375, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-14, "score" : 53.9, "model-ac" : "3syyA00" } ], "xref" : [ { "name" : "XP_018909760.1 PREDICTED: uncharacterized protein LOC109038942 [Bemisia tabaci]", "id" : "XP_018909760.1" } ] },{ "sequence" : "MTCLKLDVVKLVEHLGSAESYQILPGVSIVYSKSKRNDTSLIPADLAVSLVRDANSTEKLDRFLFQKVDNFLSSLSLNVKLLDSRVIGSVRKFSVSAFSSFFPSFWPEEGRKKKDSYHAAAMWSAGTLAAVGFSALAAMSGKALMTSMIALLLAAMSAFKHHGGGKTSHYEIITKPAHYHDHDHLHSASYTGAPYSYARHLVIAPAEDDRNGPPDEYKIPFRPYPLSPTYIPAHDK", "md5" : "e23fe92e96fac035677ad9a0e94a7b14", "matches" : [ { "signature" : { "accession" : "PTHR21879:SF9", "name" : "OSIRIS 16", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 200, "hmmStart" : 42, "hmmEnd" : 232, "hmmLength" : 242, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 214, "location-fragments" : [ { "start" : 2, "end" : 200, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-35, "familyName" : "OSIRIS 16", "score" : 125.7, "model-ac" : "PTHR21879:SF9" }, { "signature" : { "accession" : "PTHR21879", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR012464", "name" : "DUF1676", "description" : "Protein of unknown function DUF1676", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 200, "hmmStart" : 42, "hmmEnd" : 232, "hmmLength" : 242, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 214, "location-fragments" : [ { "start" : 2, "end" : 200, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-35, "familyName" : "OSIRIS 16", "score" : 125.7, "model-ac" : "PTHR21879" }, { "signature" : { "accession" : "PF07898", "name" : "DUF1676", "description" : "Protein of unknown function (DUF1676)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR012464", "name" : "DUF1676", "description" : "Protein of unknown function DUF1676", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 160, "hmmStart" : 8, "hmmEnd" : 171, "hmmLength" : 172, "hmmBounds" : "INCOMPLETE", "evalue" : 4.4E-22, "score" : 79.0, "envelopeStart" : 1, "envelopeEnd" : 161, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 160, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-22, "score" : 79.3, "model-ac" : "PF07898" } ], "xref" : [ { "name" : "XP_018909761.1 PREDICTED: uncharacterized protein LOC109038943 [Bemisia tabaci]", "id" : "XP_018909761.1" } ] },{ "sequence" : "MQILCAICCEVFTNDNLKQVCSCPCGHIFHSGCINQWFEREKTCPECRQEVKDKNLIHLFFNVEVISGDSEDTIESLKIKLDDLNCQLYSKEADVKFLKHDNESLSEQIQKLSSRLKEIQNSHQITVSTLENRTQCLNAVKRRIEELDETHKRLKTEEQEIIRVQKREIDELTRINELLRQKLNADYQNLDDSELPPFNRGDFDAPGSSSFGLKPHHKFYRNMGDEETGGYPFSSLAFPYKHQDPLGGAQPISLVKKQPYHGHPSRSHSDQPIPAHHHPSSYLPHSSKSQFHSHPKISHLPPHGRARSFDSPHLYPGQLDLPSSSKNVPKSDLPFYGFPSSSSSQCPPWLAPMPQSGFLNSSEGFVPPLSQRYSSSYQYPKEQDDIVPFPSSWVLVKQ", "md5" : "8a13b36d5c9354a5d6860ede01ae7356", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 74, "end" : 122, "location-fragments" : [ { "start" : 74, "end" : 122, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR46569", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 171, "hmmStart" : 3, "hmmEnd" : 172, "hmmLength" : 388, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 192, "location-fragments" : [ { "start" : 1, "end" : 171, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-28, "familyName" : "FAMILY NOT NAMED", "score" : 103.7, "model-ac" : "PTHR46569" }, { "signature" : { "accession" : "SM00184", "name" : "ring_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5, "end" : 47, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-5, "score" : 34.8, "location-fragments" : [ { "start" : 5, "end" : 47, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-5, "score" : 34.8, "model-ac" : "SM00184" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 248, "end" : 323, "location-fragments" : [ { "start" : 248, "end" : 323, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF13639", "name" : "zf-RING_2", "description" : "Ring finger domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5, "end" : 48, "hmmStart" : 3, "hmmEnd" : 44, "hmmLength" : 44, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.8E-8, "score" : 34.6, "envelopeStart" : 3, "envelopeEnd" : 48, "postProcessed" : true, "location-fragments" : [ { "start" : 5, "end" : 48, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.2E-9, "score" : 35.7, "model-ac" : "PF13639" }, { "signature" : { "accession" : "PS50089", "name" : "ZF_RING_2", "description" : "Zinc finger RING-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5, "end" : 48, "score" : 12.814, "alignment" : "CAICCEVFTNDnlkQVCSCPCGHIFHSGCINQW--FEREKTCPECR", "location-fragments" : [ { "start" : 5, "end" : 48, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50089" }, { "signature" : { "accession" : "SSF57850", "name" : "RING/U-box", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 66, "hmmLength" : 78, "location-fragments" : [ { "start" : 3, "end" : 66, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.06E-14, "model-ac" : "0043836" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 137, "end" : 182, "location-fragments" : [ { "start" : 137, "end" : 182, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" } ], "xref" : [ { "name" : "XP_018910256.1 PREDICTED: uncharacterized protein LOC109039292 [Bemisia tabaci]", "id" : "XP_018910256.1" } ] },{ "sequence" : "MGVEKIELGENEISQEDKAACLLREELRLVAKTELREDDAIRTHALRQMRDWISKHPDIEYCRTDAPFLLRFLRTKKFCMPLAQEMLERYLTIRQIYPHWFSRFDVLDPTLSAILDSGYLIPLPERDEYGRCVLLACIGKFDPHKYTSADMARVHSMVVELLMDDPENQVRGYTYVNDDSGLSMSHVTLWSLNDLRSIIRCIQNSTPMRHKATHFFNVPNFANKVFDFVVSLMNEKLKNRVTFHSNVDDMKRVIDPKILPREYGGEIPTADLISRLKKQLLEKREELLALDKMKINVRNKKMEFEVNDMAGSFRKLEVD", "md5" : "011e8a68d7252b40e1a7a5d16c108032", "matches" : [ { "signature" : { "accession" : "PTHR10174", "name" : "RETINALDEHYDE BINDING PROTEIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 319, "hmmStart" : 18, "hmmEnd" : 329, "hmmLength" : 329, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 4, "envelopeEnd" : 319, "location-fragments" : [ { "start" : 15, "end" : 319, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-123, "familyName" : "LD40136P", "score" : 413.2, "model-ac" : "PTHR10174" }, { "signature" : { "accession" : "SM00516", "name" : "sec14_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001251", "name" : "CRAL-TRIO_dom", "description" : "CRAL-TRIO lipid binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 107, "end" : 268, "hmmStart" : 1, "hmmEnd" : 184, "hmmLength" : 184, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-16, "score" : 70.7, "location-fragments" : [ { "start" : 107, "end" : 268, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-16, "score" : 70.7, "model-ac" : "SM00516" }, { "signature" : { "accession" : "SM01100", "name" : "CRAL_TRIO_N_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR011074", "name" : "CRAL/TRIO_N_dom", "description" : "CRAL/TRIO, N-terminal domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 65, "end" : 90, "hmmStart" : 1, "hmmEnd" : 26, "hmmLength" : 26, "hmmBounds" : "COMPLETE", "evalue" : 3.6E-6, "score" : 36.5, "location-fragments" : [ { "start" : 65, "end" : 90, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-6, "score" : 36.5, "model-ac" : "SM01100" }, { "signature" : { "accession" : "G3DSA:3.40.525.10", "name" : "Phosphatidylinositol Transfer Protein Sec14p", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036865", "name" : "CRAL-TRIO_dom_sf", "description" : "CRAL-TRIO lipid binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 97, "end" : 275, "hmmStart" : 1, "hmmEnd" : 174, "hmmLength" : 182, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-50, "score" : 172.6, "envelopeStart" : 97, "envelopeEnd" : 275, "postProcessed" : true, "location-fragments" : [ { "start" : 97, "end" : 275, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-50, "score" : 173.0, "model-ac" : "3hx3A02" }, { "signature" : { "accession" : "G3DSA:1.10.8.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 13, "end" : 95, "hmmStart" : 18, "hmmEnd" : 99, "hmmLength" : 101, "hmmBounds" : "COMPLETE", "evalue" : 7.1E-19, "score" : 69.7, "envelopeStart" : 13, "envelopeEnd" : 95, "postProcessed" : true, "location-fragments" : [ { "start" : 13, "end" : 95, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-19, "score" : 71.2, "model-ac" : "3hy5A01" }, { "signature" : { "accession" : "PS50191", "name" : "CRAL_TRIO", "description" : "CRAL-TRIO lipid binding domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001251", "name" : "CRAL-TRIO_dom", "description" : "CRAL-TRIO lipid binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 108, "end" : 271, "score" : 15.805, "alignment" : "DPTLSAILDSGYLIPLperDEYGRCVLLACIGKFDP-HKYTSADMARVHSMVVELLMDDPENQVRGY----TYVNDDSGLSMSHVTlWSLNDLRSIIRCIQNSTPMRHKATHFFNVPNFANKVFDFVVSLMNEKLKNRVTFHSN--VDDMKRVIDPKILPREYGGEIPTAD", "location-fragments" : [ { "start" : 108, "end" : 271, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50191" }, { "signature" : { "accession" : "SSF46938", "name" : "CRAL/TRIO N-terminal domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036273", "name" : "CRAL/TRIO_N_dom_sf", "description" : "CRAL/TRIO, N-terminal domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 30, "end" : 105, "hmmLength" : 82, "location-fragments" : [ { "start" : 30, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.45E-20, "model-ac" : "0048578" }, { "signature" : { "accession" : "cd00170", "name" : "SEC14", "description" : "SEC14", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR001251", "name" : "CRAL-TRIO_dom", "description" : "CRAL-TRIO lipid binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 111, "end" : 266, "sites" : [ { "description" : "phospholipid binding pocket", "numLocations" : 16, "siteLocations" : [ { "start" : 199, "end" : 199, "residue" : "I" }, { "start" : 179, "end" : 179, "residue" : "D" }, { "start" : 241, "end" : 241, "residue" : "V" }, { "start" : 195, "end" : 195, "residue" : "L" }, { "start" : 229, "end" : 229, "residue" : "V" }, { "start" : 207, "end" : 207, "residue" : "P" }, { "start" : 213, "end" : 213, "residue" : "T" }, { "start" : 162, "end" : 162, "residue" : "L" }, { "start" : 203, "end" : 203, "residue" : "Q" }, { "start" : 136, "end" : 136, "residue" : "A" }, { "start" : 210, "end" : 210, "residue" : "H" }, { "start" : 215, "end" : 215, "residue" : "F" }, { "start" : 132, "end" : 132, "residue" : "C" }, { "start" : 222, "end" : 222, "residue" : "A" }, { "start" : 134, "end" : 134, "residue" : "L" }, { "start" : 177, "end" : 177, "residue" : "N" } ] }, { "description" : "salt bridge", "numLocations" : 2, "siteLocations" : [ { "start" : 240, "end" : 240, "residue" : "R" }, { "start" : 208, "end" : 208, "residue" : "M" } ] } ], "evalue" : 5.74094E-31, "score" : 112.093, "location-fragments" : [ { "start" : 111, "end" : 266, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00170" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 273, "end" : 293, "location-fragments" : [ { "start" : 273, "end" : 293, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "SSF52087", "name" : "CRAL/TRIO domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036865", "name" : "CRAL-TRIO_dom_sf", "description" : "CRAL-TRIO lipid binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 113, "end" : 291, "hmmLength" : 185, "location-fragments" : [ { "start" : 113, "end" : 291, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.01E-47, "model-ac" : "0043136" }, { "signature" : { "accession" : "PF00650", "name" : "CRAL_TRIO", "description" : "CRAL/TRIO domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001251", "name" : "CRAL-TRIO_dom", "description" : "CRAL-TRIO lipid binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 116, "end" : 266, "hmmStart" : 4, "hmmEnd" : 159, "hmmLength" : 159, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.5E-33, "score" : 114.6, "envelopeStart" : 113, "envelopeEnd" : 266, "postProcessed" : true, "location-fragments" : [ { "start" : 116, "end" : 266, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-33, "score" : 115.0, "model-ac" : "PF00650" }, { "signature" : { "accession" : "PR00180", "name" : "CRETINALDHBP", "description" : "Cellular retinaldehyde-binding protein signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : null }, "locations" : [ { "start" : 117, "end" : 141, "pvalue" : 6.43E-5, "score" : 40.0, "motifNumber" : 2, "location-fragments" : [ { "start" : 117, "end" : 141, "dc-status" : "CONTINUOUS" } ] }, { "start" : 68, "end" : 90, "pvalue" : 2.02E-9, "score" : 48.91, "motifNumber" : 1, "location-fragments" : [ { "start" : 68, "end" : 90, "dc-status" : "CONTINUOUS" } ] }, { "start" : 193, "end" : 214, "pvalue" : 4.98E-6, "score" : 31.82, "motifNumber" : 3, "location-fragments" : [ { "start" : 193, "end" : 214, "dc-status" : "CONTINUOUS" } ] }, { "start" : 226, "end" : 245, "pvalue" : 7.79E-5, "score" : 30.0, "motifNumber" : 4, "location-fragments" : [ { "start" : 226, "end" : 245, "dc-status" : "CONTINUOUS" } ] }, { "start" : 257, "end" : 266, "pvalue" : 5.22E-5, "score" : 62.5, "motifNumber" : 5, "location-fragments" : [ { "start" : 257, "end" : 266, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-21, "graphscan" : "IIIiI", "model-ac" : "PR00180" }, { "signature" : { "accession" : "PTHR10174:SF166", "name" : "LD40136P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 319, "hmmStart" : 18, "hmmEnd" : 329, "hmmLength" : 329, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 4, "envelopeEnd" : 319, "location-fragments" : [ { "start" : 15, "end" : 319, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-123, "familyName" : "LD40136P", "score" : 413.2, "model-ac" : "PTHR10174:SF166" } ], "xref" : [ { "name" : "XP_018909968.1 PREDICTED: clavesin-1-like [Bemisia tabaci]", "id" : "XP_018909968.1" } ] },{ "sequence" : "MELLEIVKSAMDTHSVLLFLSVMVYLLYVYRDKFHYWSKRGVPCQSPAQSIVRTFRLVLRMDSFTDNFYRVYKAFDGHPYVGSLELTKPILVVRDPELARIVLVKSFSSFSGRLKSPDTTLDPLSNHLFTLNGEKWRQVRHKTATAFSTAKLKNMFHSLKDCAREMDAYMERAIGDKGDVEFDAFKVMSNYTLEVIGACAMGIKCDSIHDEETEFKRLSRDFFRFDARRMIFTLLDLLHPKLPVLLKWKAVRPEVENFFREAIKEAASLKESEAAARTDFLQILIDFQKSEKASKTDAGNDTELVFTDNIIGGVIGSFFSAGYEPTAAALTFCLYELARHPQVQAKLHEEILAVKEKLGDDIEYENLKEFKYANQVIDETLRLYPASGILVRTCTEPFKLPDSDVVIEKGTKVFVSSYGLQTDPRYFPEPEKFDPERFSEENKEKILPGTYLPFGDGPRLCIAMRLALMDVKMMMVRLVSKYEIHTTPKTPKKITFDTNSFTVQPAEKVWLRFRRRASTP", "md5" : "4602f4e8221ed90e3d85b9fea67e954c", "matches" : [ { "signature" : { "accession" : "PTHR24292", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 29, "end" : 514, "hmmStart" : 2, "hmmEnd" : 474, "hmmLength" : 474, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 11, "envelopeEnd" : 514, "location-fragments" : [ { "start" : 29, "end" : 514, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-136, "familyName" : "FAMILY NOT NAMED", "score" : 456.5, "model-ac" : "PTHR24292" }, { "signature" : { "accession" : "PR00385", "name" : "P450", "description" : "P450 superfamily signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001128", "name" : "Cyt_P450", "description" : "Cytochrome P450", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 321, "end" : 338, "pvalue" : 2.38E-6, "score" : 35.95, "motifNumber" : 1, "location-fragments" : [ { "start" : 321, "end" : 338, "dc-status" : "CONTINUOUS" } ] }, { "start" : 461, "end" : 472, "pvalue" : 0.00586, "score" : 34.12, "motifNumber" : 5, "location-fragments" : [ { "start" : 461, "end" : 472, "dc-status" : "CONTINUOUS" } ] }, { "start" : 375, "end" : 386, "pvalue" : 2.45E-5, "score" : 45.45, "motifNumber" : 3, "location-fragments" : [ { "start" : 375, "end" : 386, "dc-status" : "CONTINUOUS" } ] }, { "start" : 452, "end" : 461, "pvalue" : 4.25E-5, "score" : 60.07, "motifNumber" : 4, "location-fragments" : [ { "start" : 452, "end" : 461, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-11, "graphscan" : "I.III", "model-ac" : "PR00385" }, { "signature" : { "accession" : "PR00463", "name" : "EP450I", "description" : "E-class P450 group I signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002401", "name" : "Cyt_P450_E_grp-I", "description" : "Cytochrome P450, E-class, group I", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 374, "end" : 392, "pvalue" : 0.057, "score" : 27.1, "motifNumber" : 6, "location-fragments" : [ { "start" : 374, "end" : 392, "dc-status" : "CONTINUOUS" } ] }, { "start" : 310, "end" : 327, "pvalue" : 0.00449, "score" : 26.01, "motifNumber" : 4, "location-fragments" : [ { "start" : 310, "end" : 327, "dc-status" : "CONTINUOUS" } ] }, { "start" : 416, "end" : 440, "pvalue" : 3.83E-8, "score" : 33.26, "motifNumber" : 7, "location-fragments" : [ { "start" : 416, "end" : 440, "dc-status" : "CONTINUOUS" } ] }, { "start" : 451, "end" : 461, "pvalue" : 5.98E-5, "score" : 51.88, "motifNumber" : 8, "location-fragments" : [ { "start" : 451, "end" : 461, "dc-status" : "CONTINUOUS" } ] }, { "start" : 330, "end" : 356, "pvalue" : 1.32E-6, "score" : 32.71, "motifNumber" : 5, "location-fragments" : [ { "start" : 330, "end" : 356, "dc-status" : "CONTINUOUS" } ] }, { "start" : 461, "end" : 484, "pvalue" : 1.93E-4, "score" : 20.14, "motifNumber" : 9, "location-fragments" : [ { "start" : 461, "end" : 484, "dc-status" : "CONTINUOUS" } ] }, { "start" : 98, "end" : 119, "pvalue" : 0.00428, "score" : 26.35, "motifNumber" : 2, "location-fragments" : [ { "start" : 98, "end" : 119, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.7E-22, "graphscan" : ".i.iIiIIi", "model-ac" : "PR00463" }, { "signature" : { "accession" : "G3DSA:1.10.630.10", "name" : "Cytochrome p450", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036396", "name" : "Cyt_P450_sf", "description" : "Cytochrome P450 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 25, "end" : 519, "hmmStart" : 7, "hmmEnd" : 477, "hmmLength" : 487, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-124, "score" : 418.0, "envelopeStart" : 25, "envelopeEnd" : 519, "postProcessed" : true, "location-fragments" : [ { "start" : 25, "end" : 519, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-124, "score" : 418.4, "model-ac" : "4d6zA00" }, { "signature" : { "accession" : "PF00067", "name" : "p450", "description" : "Cytochrome P450", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001128", "name" : "Cyt_P450", "description" : "Cytochrome P450", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 79, "end" : 507, "hmmStart" : 35, "hmmEnd" : 458, "hmmLength" : 463, "hmmBounds" : "INCOMPLETE", "evalue" : 1.4E-89, "score" : 301.0, "envelopeStart" : 51, "envelopeEnd" : 512, "postProcessed" : true, "location-fragments" : [ { "start" : 79, "end" : 507, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-89, "score" : 301.3, "model-ac" : "PF00067" }, { "signature" : { "accession" : "SSF48264", "name" : "Cytochrome P450", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036396", "name" : "Cyt_P450_sf", "description" : "Cytochrome P450 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 57, "end" : 516, "hmmLength" : 463, "location-fragments" : [ { "start" : 57, "end" : 516, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.43E-109, "model-ac" : "0054912" }, { "signature" : { "accession" : "PS00086", "name" : "CYTOCHROME_P450", "description" : "Cytochrome P450 cysteine heme-iron ligand signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017972", "name" : "Cyt_P450_CS", "description" : "Cytochrome P450, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 454, "end" : 463, "level" : "STRONG", "cigarAlignment" : "2M1I7M", "alignment" : "FGdGPRLCIA", "location-fragments" : [ { "start" : 454, "end" : 463, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00086" } ], "xref" : [ { "name" : "XP_018910240.1 PREDICTED: probable cytochrome P450 6a14 [Bemisia tabaci]", "id" : "XP_018910240.1" } ] },{ "sequence" : "MPSGLGASYRSLADDVYRSTTISERDKFSVLESVKKAFNFTSFSAQALTRRSEPLISRSESSQPVVSNSAMPSDSMDDIELQNVQLQFPSARSLSREGSDVEEIKVETDRGHLLVAVQGNRSKPAIVTYHDLGLNYVSSFQAFFNYLDMRQLLNNFSVYHVNAPGQEEGAPPFPDDYEYPTMDDLAAQLNFVLTHFGLRSIIGLGVGAGGNILARFALSNPDKVEALCLINVVSTAAGWIEWGYQKLNARYLRSKGMTQGVLDYLMWHHFGRGTEERNHDLVQVYRNYFERCVNPGNLALFIDSYIRRTDLNIERDPDPNRRKEGGGSPTLSMPVMNITGSLSPHVNDTVTLNSRLDPSNSSWMKISDCGMVLEEQPNKVCEALRLFLQGLGYAVKLGRPKITNSTSAEAFIVMSVKTSRSLDSVRSAPWSIRITENPISETAAC", "md5" : "a3f3a255486c6b32bcad8bb88507d5f3", "matches" : [ { "signature" : { "accession" : "PTHR11034", "name" : "N-MYC DOWNSTREAM REGULATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR004142", "name" : "NDRG", "description" : "NDRG", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 104, "end" : 402, "hmmStart" : 3, "hmmEnd" : 294, "hmmLength" : 301, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 30, "envelopeEnd" : 413, "location-fragments" : [ { "start" : 104, "end" : 402, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-128, "familyName" : "GH09802P", "score" : 429.4, "model-ac" : "PTHR11034" }, { "signature" : { "accession" : "PF03096", "name" : "Ndr", "description" : "Ndr family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004142", "name" : "NDRG", "description" : "NDRG", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 105, "end" : 393, "hmmStart" : 3, "hmmEnd" : 281, "hmmLength" : 283, "hmmBounds" : "INCOMPLETE", "evalue" : 2.1E-103, "score" : 344.9, "envelopeStart" : 103, "envelopeEnd" : 395, "postProcessed" : true, "location-fragments" : [ { "start" : 105, "end" : 393, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-103, "score" : 345.3, "model-ac" : "PF03096" }, { "signature" : { "accession" : "PTHR11034:SF19", "name" : "GH09802P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 104, "end" : 402, "hmmStart" : 3, "hmmEnd" : 294, "hmmLength" : 301, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 30, "envelopeEnd" : 413, "location-fragments" : [ { "start" : 104, "end" : 402, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-128, "familyName" : "GH09802P", "score" : 429.4, "model-ac" : "PTHR11034:SF19" }, { "signature" : { "accession" : "SSF53474", "name" : "alpha/beta-Hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 101, "end" : 389, "hmmLength" : 281, "location-fragments" : [ { "start" : 101, "end" : 389, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.55E-26, "model-ac" : "0046077" }, { "signature" : { "accession" : "G3DSA:3.40.50.1820", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 94, "end" : 390, "hmmStart" : 9, "hmmEnd" : 286, "hmmLength" : 286, "hmmBounds" : "COMPLETE", "evalue" : 4.1E-93, "score" : 313.9, "envelopeStart" : 94, "envelopeEnd" : 390, "postProcessed" : true, "location-fragments" : [ { "start" : 94, "end" : 390, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-93, "score" : 314.3, "model-ac" : "2qmqA00" } ], "xref" : [ { "name" : "XP_018910068.1 PREDICTED: protein NDRG3 isoform X2 [Bemisia tabaci]", "id" : "XP_018910068.1" } ] },{ "sequence" : "MCTGSNTVPVDCGKSRNRNGDRASSDKVLWAEENNYINYGEEDQMEVYGYASSFIRKMSIWILMCLTCGIVRLVFHWWPEWMLYATHRRCPLNEAEKILVINNYEGHIISHFVKDVKLISIHDLSSDSTKDKDRISGLDIQALVQLQSNLRSKKLKAFLFDGSRKAREFPKINSLRNLDRYVFLKLHVIWHSESIMVSTKIRISVFHQAGRNYETG", "md5" : "5f1de9d443ed03c7ad0c3ee3ded3007b", "matches" : [ { "signature" : { "accession" : "PTHR45630", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 33, "end" : 193, "hmmStart" : 16, "hmmEnd" : 160, "hmmLength" : 1160, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 208, "location-fragments" : [ { "start" : 33, "end" : 193, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-15, "familyName" : "CATION-TRANSPORTING ATPASE 13A2", "score" : 56.2, "model-ac" : "PTHR45630" }, { "signature" : { "accession" : "PF12409", "name" : "P5-ATPase", "description" : "P5-type ATPase cation transporter", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006544", "name" : "P-type_TPase_V", "description" : "P-type ATPase, subfamily V", "type" : "FAMILY", "goXRefs" : [ { "name" : "ATPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016887" }, { "name" : "cation transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006812" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ { "name" : "Ion transport by P-type ATPases", "databaseName" : "Reactome", "id" : "R-HSA-936837" } ] } }, "locations" : [ { "start" : 41, "end" : 128, "hmmStart" : 1, "hmmEnd" : 85, "hmmLength" : 126, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.2E-21, "score" : 77.1, "envelopeStart" : 41, "envelopeEnd" : 167, "postProcessed" : true, "location-fragments" : [ { "start" : 41, "end" : 128, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-22, "score" : 77.6, "model-ac" : "PF12409" }, { "signature" : { "accession" : "PTHR45630:SF2", "name" : "CATION-TRANSPORTING ATPASE 13A2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 33, "end" : 193, "hmmStart" : 16, "hmmEnd" : 160, "hmmLength" : 1160, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 208, "location-fragments" : [ { "start" : 33, "end" : 193, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-15, "familyName" : "CATION-TRANSPORTING ATPASE 13A2", "score" : 56.2, "model-ac" : "PTHR45630:SF2" } ], "xref" : [ { "name" : "XP_018909882.1 PREDICTED: probable cation-transporting ATPase 13A5 isoform X2 [Bemisia tabaci]", "id" : "XP_018909882.1" } ] },{ "sequence" : "MTSLPRPSEKRLQKELLSLIKDPPPGVLVDSEKASQNLSIWTIYMKGADETLFAGEEFQLQFKFSPKYPFDSPEVTFIGPNIPVHPHVYSNGHICLSILTEDWSPALSVQSVCLSIISMLSSCKEKKRPSDNAFYVKTCSKNPKKTKWWYHDDTV", "md5" : "57ee96efffe7535d27888be734a01a2c", "matches" : [ { "signature" : { "accession" : "SM00212", "name" : "ubc_7", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 155, "hmmStart" : 1, "hmmEnd" : 144, "hmmLength" : 144, "hmmBounds" : "COMPLETE", "evalue" : 4.6E-36, "score" : 135.8, "location-fragments" : [ { "start" : 10, "end" : 155, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-36, "score" : 135.8, "model-ac" : "SM00212" }, { "signature" : { "accession" : "PS50127", "name" : "UBIQUITIN_CONJUGAT_2", "description" : "Ubiquitin-conjugating enzymes family profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000608", "name" : "UBQ-conjugat_E2", "description" : "Ubiquitin-conjugating enzyme E2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" } ] } }, "locations" : [ { "start" : 10, "end" : 122, "score" : 26.178, "alignment" : "KRLQKELLSLIKDPPPGVLVDSEKASqNLSIWTIYMKGADETLFAGEEFQLQFKFSPKYPFDSPEVTFIGpnIPVHPHVYSNGHICLSILTEDWSPALSVQSVCLSIISMLSS------------------------", "location-fragments" : [ { "start" : 10, "end" : 122, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50127" }, { "signature" : { "accession" : "PTHR24068", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 154, "hmmStart" : 5, "hmmEnd" : 148, "hmmLength" : 149, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 155, "location-fragments" : [ { "start" : 10, "end" : 154, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-57, "familyName" : "UBIQUITIN-CONJUGATING ENZYME E2 W", "score" : 195.8, "model-ac" : "PTHR24068" }, { "signature" : { "accession" : "cd00195", "name" : "UBCc", "description" : "UBCc", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000608", "name" : "UBQ-conjugat_E2", "description" : "Ubiquitin-conjugating enzyme E2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" } ] } }, "locations" : [ { "start" : 9, "end" : 123, "sites" : [ { "description" : "E3 interaction residues", "numLocations" : 5, "siteLocations" : [ { "start" : 10, "end" : 10, "residue" : "K" }, { "start" : 69, "end" : 69, "residue" : "P" }, { "start" : 70, "end" : 70, "residue" : "F" }, { "start" : 105, "end" : 105, "residue" : "P" }, { "start" : 106, "end" : 106, "residue" : "A" } ] }, { "description" : "Ub thioester intermediate interaction residues", "numLocations" : 18, "siteLocations" : [ { "start" : 115, "end" : 115, "residue" : "S" }, { "start" : 96, "end" : 96, "residue" : "L" }, { "start" : 121, "end" : 121, "residue" : "S" }, { "start" : 82, "end" : 82, "residue" : "I" }, { "start" : 98, "end" : 98, "residue" : "I" }, { "start" : 99, "end" : 99, "residue" : "L" }, { "start" : 95, "end" : 95, "residue" : "C" }, { "start" : 112, "end" : 112, "residue" : "V" }, { "start" : 104, "end" : 104, "residue" : "S" }, { "start" : 118, "end" : 118, "residue" : "S" }, { "start" : 103, "end" : 103, "residue" : "W" }, { "start" : 87, "end" : 87, "residue" : "H" }, { "start" : 81, "end" : 81, "residue" : "N" }, { "start" : 90, "end" : 90, "residue" : "S" }, { "start" : 107, "end" : 107, "residue" : "L" }, { "start" : 122, "end" : 122, "residue" : "S" }, { "start" : 88, "end" : 88, "residue" : "V" }, { "start" : 94, "end" : 94, "residue" : "I" } ] }, { "description" : "active site cysteine", "numLocations" : 1, "siteLocations" : [ { "start" : 95, "end" : 95, "residue" : "C" } ] } ], "evalue" : 2.38949E-35, "score" : 117.688, "location-fragments" : [ { "start" : 9, "end" : 123, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00195" }, { "signature" : { "accession" : "G3DSA:3.10.110.10", "name" : "Ubiquitin Conjugating Enzyme", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR016135", "name" : "UBQ-conjugating_enzyme/RWD", "description" : "Ubiquitin-conjugating enzyme/RWD-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 155, "hmmStart" : 5, "hmmEnd" : 150, "hmmLength" : 151, "hmmBounds" : "COMPLETE", "evalue" : 3.9E-59, "score" : 200.5, "envelopeStart" : 7, "envelopeEnd" : 155, "postProcessed" : true, "location-fragments" : [ { "start" : 7, "end" : 155, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-59, "score" : 200.7, "model-ac" : "2mt6A00" }, { "signature" : { "accession" : "SSF54495", "name" : "UBC-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016135", "name" : "UBQ-conjugating_enzyme/RWD", "description" : "Ubiquitin-conjugating enzyme/RWD-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 136, "hmmLength" : 162, "location-fragments" : [ { "start" : 8, "end" : 136, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.67E-38, "model-ac" : "0053118" }, { "signature" : { "accession" : "PF00179", "name" : "UQ_con", "description" : "Ubiquitin-conjugating enzyme", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000608", "name" : "UBQ-conjugat_E2", "description" : "Ubiquitin-conjugating enzyme E2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" } ] } }, "locations" : [ { "start" : 11, "end" : 144, "hmmStart" : 1, "hmmEnd" : 131, "hmmLength" : 140, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.1E-34, "score" : 118.1, "envelopeStart" : 11, "envelopeEnd" : 151, "postProcessed" : true, "location-fragments" : [ { "start" : 11, "end" : 144, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-34, "score" : 118.4, "model-ac" : "PF00179" }, { "signature" : { "accession" : "PTHR24068:SF153", "name" : "UBIQUITIN-CONJUGATING ENZYME E2 W", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 154, "hmmStart" : 5, "hmmEnd" : 148, "hmmLength" : 149, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 155, "location-fragments" : [ { "start" : 10, "end" : 154, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-57, "familyName" : "UBIQUITIN-CONJUGATING ENZYME E2 W", "score" : 195.8, "model-ac" : "PTHR24068:SF153" } ], "xref" : [ { "name" : "XP_018910213.1 PREDICTED: ubiquitin-conjugating enzyme E2 W [Bemisia tabaci]", "id" : "XP_018910213.1" } ] },{ "sequence" : "MPLPKRVIEPVHVSRGTIPPDFPLPSELEAATNGTLANAVRQLSSLSRHAEDLFGELAKSVHSLATRAGSLQVRLDRLAVKVTELDSNVEEVSLQDIHMRKAFKSAVSFDQEVVGRKTMPTAMLETYNQCDKPPPLDKLNPYREDGKDGLKFYTDPSYFFDLWSQETEKETERVMHDRGKKPHKYRRGQDGTGANGIGNRHKKHVRQPHNTRERQRQLAVGHGEYIMSQNTHYRTPQQVFDLSHEEAMMGGYIMTTDMRPNRPNSIELRRNYPEHVTDAIYTPNNIHYRSTNNGILGGMGTMVYDENQLNYGSPQMTGNMVSHYGSNAILSPAENCVSPSRRIRPSQPPPAPPSNSNSASSTPLVGSVSNTPTRGRSASTGRDTLPPPPPPPIETPTPPPIEPLPPPPAPLPVMPPAPSPPRACSPPAPPPPPPPPPLPMMPNGLIPTLNGDVAKSPKQIIPNSPPKQTEKNSAINPPAKNKPSAQVLQHDPRSDLLKAIRDGIKLRKVEKIEQKEGERVNAHDVASILARRVAVEVSDSDSASASESEYDSDGWVDPHETSA", "md5" : "920e018458c0c68a61421dc058fe9749", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 383, "end" : 443, "location-fragments" : [ { "start" : 383, "end" : 443, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 461, "end" : 483, "location-fragments" : [ { "start" : 461, "end" : 483, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 332, "end" : 494, "location-fragments" : [ { "start" : 332, "end" : 494, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12902", "name" : "WASP-1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR028288", "name" : "SCAR/WAVE_fam", "description" : "SCAR/WAVE family", "type" : "FAMILY", "goXRefs" : [ { "name" : "cytoskeleton", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005856" }, { "name" : "actin cytoskeleton organization", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0030036" } ], "pathwayXRefs" : [ { "name" : "Regulation of actin dynamics for phagocytic cup formation", "databaseName" : "Reactome", "id" : "R-HSA-2029482" }, { "name" : "RHO GTPases Activate WASPs and WAVEs", "databaseName" : "Reactome", "id" : "R-HSA-5663213" }, { "name" : "VEGFA-VEGFR2 Pathway", "databaseName" : "Reactome", "id" : "R-HSA-4420097" } ] } }, "locations" : [ { "start" : 1, "end" : 557, "hmmStart" : 1, "hmmEnd" : 499, "hmmLength" : 499, "hmmBounds" : "COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 557, "location-fragments" : [ { "start" : 1, "end" : 557, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-90, "familyName" : "WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER 2", "score" : 308.2, "model-ac" : "PTHR12902" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 174, "end" : 221, "location-fragments" : [ { "start" : 174, "end" : 221, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51082", "name" : "WH2", "description" : "WH2 domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR003124", "name" : "WH2_dom", "description" : "WH2 domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "actin binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003779" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 492, "end" : 509, "score" : 10.179, "alignment" : "PRSDLLKAIRD-G-IKLRKV", "location-fragments" : [ { "start" : 492, "end" : 509, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51082" }, { "signature" : { "accession" : "G3DSA:1.20.5.340", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 87, "hmmStart" : 1, "hmmEnd" : 84, "hmmLength" : 85, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-31, "score" : 109.7, "envelopeStart" : 1, "envelopeEnd" : 87, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 87, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-31, "score" : 110.4, "model-ac" : "4n78D01" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 536, "end" : 563, "location-fragments" : [ { "start" : 536, "end" : 563, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 357, "end" : 380, "location-fragments" : [ { "start" : 357, "end" : 380, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.20.58.1570", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 467, "end" : 557, "hmmStart" : 88, "hmmEnd" : 162, "hmmLength" : 163, "hmmBounds" : "COMPLETE", "evalue" : 3.1E-21, "score" : 77.8, "envelopeStart" : 467, "envelopeEnd" : 557, "postProcessed" : true, "location-fragments" : [ { "start" : 467, "end" : 557, "dc-status" : "CONTINUOUS" } ] }, { "start" : 88, "end" : 227, "hmmStart" : 3, "hmmEnd" : 103, "hmmLength" : 163, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-39, "score" : 136.8, "envelopeStart" : 88, "envelopeEnd" : 227, "postProcessed" : true, "location-fragments" : [ { "start" : 88, "end" : 227, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-62, "score" : 212.5, "model-ac" : "3p8cD02" }, { "signature" : { "accession" : "SM00246", "name" : "wh2_8", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003124", "name" : "WH2_dom", "description" : "WH2 domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "actin binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003779" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 492, "end" : 509, "hmmStart" : 1, "hmmEnd" : 19, "hmmLength" : 19, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-4, "score" : 30.5, "location-fragments" : [ { "start" : 492, "end" : 509, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-4, "score" : 30.5, "model-ac" : "SM00246" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 174, "end" : 188, "location-fragments" : [ { "start" : 174, "end" : 188, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12902:SF6", "name" : "WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER 2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 557, "hmmStart" : 1, "hmmEnd" : 499, "hmmLength" : 499, "hmmBounds" : "COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 557, "location-fragments" : [ { "start" : 1, "end" : 557, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-90, "familyName" : "WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER 2", "score" : 308.2, "model-ac" : "PTHR12902:SF6" } ], "xref" : [ { "name" : "XP_018909799.1 PREDICTED: wiskott-Aldrich syndrome protein family member 2 [Bemisia tabaci]", "id" : "XP_018909799.1" } ] },{ "sequence" : "MGCALSSSREKEAVERSKKIDKDLRADGEKAAREVKLLLLGAGESGKSTIVKQMKIIHETGYSKEECEQYRPVVFSNTIQSLMAIIRAMGQLRIDFADPGKADTARQFFTLASAAEEGEITPELVAIMKSLWQDPGVQLCFSRSREYQLNDSAAYYLNALDRISMPNYVPTQQDVLHTRVKTTGIIETHFTFKGLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESMKLFDSICNSKWFVETSIILFLNKKDLFEEKISKSPLTICFPEYQGSNTYEEAAAYIQMKFENLNKRKDQKEIYTHFTCATDTNNIQFVFDAVTDVIIKNNLKDCGLF", "md5" : "49dd7c5b1f2ae32fde9eb03f418469c3", "matches" : [ { "signature" : { "accession" : "PF00503", "name" : "G-alpha", "description" : "G-protein alpha subunit", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001019", "name" : "Gprotein_alpha_su", "description" : "Guanine nucleotide binding protein (G-protein), alpha subunit", "type" : "FAMILY", "goXRefs" : [ { "name" : "guanyl nucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0019001" }, { "name" : "GTPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003924" }, { "name" : "G-protein beta/gamma-subunit complex binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0031683" }, { "name" : "G protein-coupled receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007186" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 16, "end" : 344, "hmmStart" : 3, "hmmEnd" : 354, "hmmLength" : 354, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.1E-124, "score" : 415.3, "envelopeStart" : 14, "envelopeEnd" : 344, "postProcessed" : true, "location-fragments" : [ { "start" : 16, "end" : 344, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-124, "score" : 415.5, "model-ac" : "PF00503" }, { "signature" : { "accession" : "G3DSA:1.10.400.10", "name" : "GI Alpha 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011025", "name" : "GproteinA_insert", "description" : "G protein alpha subunit, helical insertion", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 63, "end" : 181, "hmmStart" : 1, "hmmEnd" : 310, "hmmLength" : 310, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-152, "score" : 509.2, "envelopeStart" : 36, "envelopeEnd" : 345, "postProcessed" : true, "location-fragments" : [ { "start" : 63, "end" : 181, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-152, "score" : 509.4, "model-ac" : "4n0dA02" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 36, "end" : 345, "hmmStart" : 1, "hmmEnd" : 310, "hmmLength" : 204, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.6E-152, "score" : 509.2, "envelopeStart" : 36, "envelopeEnd" : 345, "postProcessed" : true, "location-fragments" : [ { "start" : 36, "end" : 62, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 182, "end" : 345, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.4E-152, "score" : 509.4, "model-ac" : "4n0dA01" }, { "signature" : { "accession" : "cd00066", "name" : "G-alpha", "description" : "G-alpha", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR001019", "name" : "Gprotein_alpha_su", "description" : "Guanine nucleotide binding protein (G-protein), alpha subunit", "type" : "FAMILY", "goXRefs" : [ { "name" : "guanyl nucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0019001" }, { "name" : "GTPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003924" }, { "name" : "G-protein beta/gamma-subunit complex binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0031683" }, { "name" : "G protein-coupled receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007186" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 35, "end" : 349, "sites" : [ { "description" : "GTP/Mg2+ binding site", "numLocations" : 12, "siteLocations" : [ { "start" : 204, "end" : 204, "residue" : "G" }, { "start" : 326, "end" : 326, "residue" : "C" }, { "start" : 41, "end" : 41, "residue" : "G" }, { "start" : 47, "end" : 47, "residue" : "K" }, { "start" : 182, "end" : 182, "residue" : "T" }, { "start" : 271, "end" : 271, "residue" : "K" }, { "start" : 201, "end" : 201, "residue" : "D" }, { "start" : 273, "end" : 273, "residue" : "D" }, { "start" : 270, "end" : 270, "residue" : "N" }, { "start" : 327, "end" : 327, "residue" : "A" }, { "start" : 46, "end" : 46, "residue" : "G" }, { "start" : 48, "end" : 48, "residue" : "S" } ] }, { "description" : "GoLoco binding site", "numLocations" : 16, "siteLocations" : [ { "start" : 204, "end" : 204, "residue" : "G" }, { "start" : 212, "end" : 212, "residue" : "W" }, { "start" : 83, "end" : 83, "residue" : "M" }, { "start" : 44, "end" : 44, "residue" : "E" }, { "start" : 216, "end" : 216, "residue" : "F" }, { "start" : 42, "end" : 42, "residue" : "A" }, { "start" : 43, "end" : 43, "residue" : "G" }, { "start" : 86, "end" : 86, "residue" : "I" }, { "start" : 72, "end" : 72, "residue" : "P" }, { "start" : 80, "end" : 80, "residue" : "Q" }, { "start" : 179, "end" : 179, "residue" : "R" }, { "start" : 105, "end" : 105, "residue" : "A" }, { "start" : 76, "end" : 76, "residue" : "S" }, { "start" : 108, "end" : 108, "residue" : "F" }, { "start" : 150, "end" : 150, "residue" : "N" }, { "start" : 87, "end" : 87, "residue" : "R" } ] }, { "description" : "adenylyl cyclase interaction site", "numLocations" : 5, "siteLocations" : [ { "start" : 210, "end" : 210, "residue" : "K" }, { "start" : 217, "end" : 217, "residue" : "E" }, { "start" : 213, "end" : 213, "residue" : "I" }, { "start" : 214, "end" : 214, "residue" : "H" }, { "start" : 185, "end" : 185, "residue" : "I" } ] }, { "description" : "Switch I region", "numLocations" : 9, "siteLocations" : [ { "start" : 177, "end" : 177, "residue" : "H" }, { "start" : 179, "end" : 179, "residue" : "R" }, { "start" : 182, "end" : 182, "residue" : "T" }, { "start" : 180, "end" : 180, "residue" : "V" }, { "start" : 181, "end" : 181, "residue" : "K" }, { "start" : 183, "end" : 183, "residue" : "T" }, { "start" : 184, "end" : 184, "residue" : "G" }, { "start" : 178, "end" : 178, "residue" : "T" }, { "start" : 185, "end" : 185, "residue" : "I" } ] }, { "description" : "putative receptor binding site", "numLocations" : 16, "siteLocations" : [ { "start" : 326, "end" : 326, "residue" : "C" }, { "start" : 334, "end" : 334, "residue" : "Q" }, { "start" : 333, "end" : 333, "residue" : "I" }, { "start" : 324, "end" : 324, "residue" : "F" }, { "start" : 329, "end" : 329, "residue" : "D" }, { "start" : 331, "end" : 331, "residue" : "N" }, { "start" : 320, "end" : 320, "residue" : "I" }, { "start" : 325, "end" : 325, "residue" : "T" }, { "start" : 323, "end" : 323, "residue" : "H" }, { "start" : 319, "end" : 319, "residue" : "E" }, { "start" : 318, "end" : 318, "residue" : "K" }, { "start" : 327, "end" : 327, "residue" : "A" }, { "start" : 322, "end" : 322, "residue" : "T" }, { "start" : 332, "end" : 332, "residue" : "N" }, { "start" : 321, "end" : 321, "residue" : "Y" }, { "start" : 328, "end" : 328, "residue" : "T" } ] }, { "description" : "Switch II region", "numLocations" : 17, "siteLocations" : [ { "start" : 204, "end" : 204, "residue" : "G" }, { "start" : 210, "end" : 210, "residue" : "K" }, { "start" : 212, "end" : 212, "residue" : "W" }, { "start" : 209, "end" : 209, "residue" : "R" }, { "start" : 202, "end" : 202, "residue" : "V" }, { "start" : 205, "end" : 205, "residue" : "Q" }, { "start" : 216, "end" : 216, "residue" : "F" }, { "start" : 203, "end" : 203, "residue" : "G" }, { "start" : 208, "end" : 208, "residue" : "E" }, { "start" : 217, "end" : 217, "residue" : "E" }, { "start" : 206, "end" : 206, "residue" : "R" }, { "start" : 213, "end" : 213, "residue" : "I" }, { "start" : 218, "end" : 218, "residue" : "G" }, { "start" : 207, "end" : 207, "residue" : "S" }, { "start" : 211, "end" : 211, "residue" : "K" }, { "start" : 215, "end" : 215, "residue" : "C" }, { "start" : 214, "end" : 214, "residue" : "H" } ] }, { "description" : "G5 box", "numLocations" : 3, "siteLocations" : [ { "start" : 326, "end" : 326, "residue" : "C" }, { "start" : 327, "end" : 327, "residue" : "A" }, { "start" : 328, "end" : 328, "residue" : "T" } ] }, { "description" : "G3 box", "numLocations" : 4, "siteLocations" : [ { "start" : 204, "end" : 204, "residue" : "G" }, { "start" : 201, "end" : 201, "residue" : "D" }, { "start" : 202, "end" : 202, "residue" : "V" }, { "start" : 203, "end" : 203, "residue" : "G" } ] }, { "description" : "G1 box", "numLocations" : 8, "siteLocations" : [ { "start" : 41, "end" : 41, "residue" : "G" }, { "start" : 47, "end" : 47, "residue" : "K" }, { "start" : 44, "end" : 44, "residue" : "E" }, { "start" : 45, "end" : 45, "residue" : "S" }, { "start" : 46, "end" : 46, "residue" : "G" }, { "start" : 48, "end" : 48, "residue" : "S" }, { "start" : 42, "end" : 42, "residue" : "A" }, { "start" : 43, "end" : 43, "residue" : "G" } ] }, { "description" : "G4 box", "numLocations" : 4, "siteLocations" : [ { "start" : 271, "end" : 271, "residue" : "K" }, { "start" : 272, "end" : 272, "residue" : "K" }, { "start" : 273, "end" : 273, "residue" : "D" }, { "start" : 270, "end" : 270, "residue" : "N" } ] }, { "description" : "G2 box", "numLocations" : 1, "siteLocations" : [ { "start" : 182, "end" : 182, "residue" : "T" } ] }, { "description" : "beta - gamma complex interaction site", "numLocations" : 15, "siteLocations" : [ { "start" : 204, "end" : 204, "residue" : "G" }, { "start" : 212, "end" : 212, "residue" : "W" }, { "start" : 198, "end" : 198, "residue" : "K" }, { "start" : 187, "end" : 187, "residue" : "E" }, { "start" : 200, "end" : 200, "residue" : "F" }, { "start" : 205, "end" : 205, "residue" : "Q" }, { "start" : 216, "end" : 216, "residue" : "F" }, { "start" : 208, "end" : 208, "residue" : "E" }, { "start" : 217, "end" : 217, "residue" : "E" }, { "start" : 206, "end" : 206, "residue" : "R" }, { "start" : 183, "end" : 183, "residue" : "T" }, { "start" : 211, "end" : 211, "residue" : "K" }, { "start" : 215, "end" : 215, "residue" : "C" }, { "start" : 214, "end" : 214, "residue" : "H" }, { "start" : 185, "end" : 185, "residue" : "I" } ] } ], "evalue" : 0.0, "score" : 587.571, "location-fragments" : [ { "start" : 35, "end" : 349, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00066" }, { "signature" : { "accession" : "PR00318", "name" : "GPROTEINA", "description" : "Alpha G protein (transducin) signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001019", "name" : "Gprotein_alpha_su", "description" : "Guanine nucleotide binding protein (G-protein), alpha subunit", "type" : "FAMILY", "goXRefs" : [ { "name" : "guanyl nucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0019001" }, { "name" : "GTPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003924" }, { "name" : "G-protein beta/gamma-subunit complex binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0031683" }, { "name" : "G protein-coupled receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007186" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 36, "end" : 51, "pvalue" : 2.25E-12, "score" : 89.38, "motifNumber" : 1, "location-fragments" : [ { "start" : 36, "end" : 51, "dc-status" : "CONTINUOUS" } ] }, { "start" : 197, "end" : 214, "pvalue" : 1.32E-11, "score" : 83.9, "motifNumber" : 3, "location-fragments" : [ { "start" : 197, "end" : 214, "dc-status" : "CONTINUOUS" } ] }, { "start" : 265, "end" : 274, "pvalue" : 1.28E-6, "score" : 85.36, "motifNumber" : 5, "location-fragments" : [ { "start" : 265, "end" : 274, "dc-status" : "CONTINUOUS" } ] }, { "start" : 168, "end" : 190, "pvalue" : 3.22E-15, "score" : 67.1, "motifNumber" : 2, "location-fragments" : [ { "start" : 168, "end" : 190, "dc-status" : "CONTINUOUS" } ] }, { "start" : 219, "end" : 247, "pvalue" : 1.11E-16, "score" : 66.04, "motifNumber" : 4, "location-fragments" : [ { "start" : 219, "end" : 247, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-53, "graphscan" : "IIIII", "model-ac" : "PR00318" }, { "signature" : { "accession" : "PS51882", "name" : "G_ALPHA", "description" : "G-alpha domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 33, "end" : 355, "score" : 112.213, "alignment" : "REVKLLLLGAGESGKSTIVKQMKIIHETGYSKEECEQYRPVVFSNTIQSLMAIIRAMGQLRIDFADPGKADTARQFFTLASAAEEG----EITPELVAIMKSLWQDPGVQLCFSRSREYQLNDSAAYYLNALDRISMPNYVPTQQDVLHTRVKTTGIIETHFTFKGLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESMKLFDSICNSKWFVETSIILFLNKKDLFEEKISKSPLTICFPEYQGSNTYEEA-AAYIQMKFENLNKRKDQKEIYTHFTCATDTNNIQFVFDAVTDVIIKNNLKDCGLF", "location-fragments" : [ { "start" : 33, "end" : 355, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51882" }, { "signature" : { "accession" : "SM00275", "name" : "galpha_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001019", "name" : "Gprotein_alpha_su", "description" : "Guanine nucleotide binding protein (G-protein), alpha subunit", "type" : "FAMILY", "goXRefs" : [ { "name" : "guanyl nucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0019001" }, { "name" : "GTPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003924" }, { "name" : "G-protein beta/gamma-subunit complex binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0031683" }, { "name" : "G protein-coupled receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007186" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 354, "hmmStart" : 1, "hmmEnd" : 400, "hmmLength" : 400, "hmmBounds" : "COMPLETE", "evalue" : 4.6E-224, "score" : 760.3, "location-fragments" : [ { "start" : 14, "end" : 354, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-224, "score" : 760.3, "model-ac" : "SM00275" }, { "signature" : { "accession" : "PTHR10218:SF227", "name" : "GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 354, "hmmStart" : 1, "hmmEnd" : 353, "hmmLength" : 354, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 355, "location-fragments" : [ { "start" : 1, "end" : 354, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-212, "familyName" : "GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-1", "score" : 706.3, "model-ac" : "PTHR10218:SF227" }, { "signature" : { "accession" : "SSF47895", "name" : "Transducin (alpha subunit), insertion domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011025", "name" : "GproteinA_insert", "description" : "G protein alpha subunit, helical insertion", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 62, "end" : 182, "hmmLength" : 121, "location-fragments" : [ { "start" : 62, "end" : 182, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.58E-43, "model-ac" : "0036001" }, { "signature" : { "accession" : "PR00441", "name" : "GPROTEINAI", "description" : "G protein alpha subunit group I signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001408", "name" : "Gprotein_alpha_I", "description" : "G-protein alpha subunit, group I", "type" : "FAMILY", "goXRefs" : [ { "name" : "GTP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005525" }, { "name" : "GTPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003924" }, { "name" : "G-protein beta/gamma-subunit complex binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0031683" }, { "name" : "G protein-coupled receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007186" }, { "name" : "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007188" } ], "pathwayXRefs" : [ { "name" : "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding", "databaseName" : "Reactome", "id" : "R-HSA-6814122" }, { "name" : "G alpha (i) signalling events", "databaseName" : "Reactome", "id" : "R-HSA-418594" }, { "name" : "PLC beta mediated events", "databaseName" : "Reactome", "id" : "R-HSA-112043" }, { "name" : "G-protein activation", "databaseName" : "Reactome", "id" : "R-HSA-202040" } ] } }, "locations" : [ { "start" : 80, "end" : 89, "pvalue" : 1.37E-6, "score" : 76.84, "motifNumber" : 1, "location-fragments" : [ { "start" : 80, "end" : 89, "dc-status" : "CONTINUOUS" } ] }, { "start" : 344, "end" : 355, "pvalue" : 3.43E-8, "score" : 82.31, "motifNumber" : 5, "location-fragments" : [ { "start" : 344, "end" : 355, "dc-status" : "CONTINUOUS" } ] }, { "start" : 279, "end" : 291, "pvalue" : 2.38E-8, "score" : 81.24, "motifNumber" : 3, "location-fragments" : [ { "start" : 279, "end" : 291, "dc-status" : "CONTINUOUS" } ] }, { "start" : 186, "end" : 196, "pvalue" : 1.58E-6, "score" : 70.81, "motifNumber" : 2, "location-fragments" : [ { "start" : 186, "end" : 196, "dc-status" : "CONTINUOUS" } ] }, { "start" : 297, "end" : 308, "pvalue" : 2.62E-6, "score" : 67.98, "motifNumber" : 4, "location-fragments" : [ { "start" : 297, "end" : 308, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-27, "graphscan" : "IIIII", "model-ac" : "PR00441" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 33, "end" : 354, "hmmLength" : 224, "location-fragments" : [ { "start" : 33, "end" : 58, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 175, "end" : 354, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 3.6E-62, "model-ac" : "0035281" }, { "signature" : { "accession" : "PTHR10218", "name" : "GTP-BINDING PROTEIN ALPHA SUBUNIT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR001019", "name" : "Gprotein_alpha_su", "description" : "Guanine nucleotide binding protein (G-protein), alpha subunit", "type" : "FAMILY", "goXRefs" : [ { "name" : "guanyl nucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0019001" }, { "name" : "GTPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003924" }, { "name" : "G-protein beta/gamma-subunit complex binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0031683" }, { "name" : "G protein-coupled receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007186" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 354, "hmmStart" : 1, "hmmEnd" : 353, "hmmLength" : 354, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 355, "location-fragments" : [ { "start" : 1, "end" : 354, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-212, "familyName" : "GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-1", "score" : 706.3, "model-ac" : "PTHR10218" } ], "xref" : [ { "name" : "XP_018909651.1 PREDICTED: guanine nucleotide-binding protein G(i) subunit alpha [Bemisia tabaci]", "id" : "XP_018909651.1" } ] },{ "sequence" : "MWWWLCSPNPLHLIAGLSFLVNYVSVTMNWILPSSIIFVLIYQAMSSGVFELRLKSFRNEQGRDNLRRCCSGEKSDLCASPCRTKFRVCLKHYQATVDTTSGCTFGNFWTPVLGENSVEIGDTTIQGFTNPMKFPFEFAWPGTFSLIVEAWHDTNTTEGPVTPGMGVLIKRLTTQRYLHISENWTEAVHNSDHSLMSYEFRVTCDPHYYGNGCANLCRPRDDKFGHYSCSLQGDRVCLPGWKGDYCTKPICLPGCDDQHGHCSKPGECLCHSGWKGRLCDECERYPGCLHGSCQKPWDCLCNEGWGGLFCNQDLNYCTNHKPCRNGGTCFNTGQGSYTCSCPPGFAGENCEQELNDCAHQPCLNGGTCKELGNGYKCECPKNWLGAHCEISTMSCDDRPCHHGGTCLPTAHGYTCQCAPGYTGTDCQNLKDHCNPSPCANGGTCSVLAGNAGYTCACPSGFSGLKCEVNNDDCHGNPCRNGGTCIDQVNKFRCQCKPGFVGDLCESKVDCCLLAPCANGGTCIVLPNDFQCKCRPGFTGKDCSEDVNECASSPCANGGTCVNRVNGFRCDCADGFSGSLCKTEDVATVSNISRHVSIQVEESGLTTEHIVVIVTLSIAVPALVLMAATAVWCMKHQRKREQQRADDLARMQNEQNAVHSHVAKRGNCNAHMIKNTWTPGPGPCPYIKNIEVSPGDPCFVKPVTPGDPCFVKPITPGDPCFGKAVLSPPPDPAPVYTLQRSKSQSTGWKSEYV", "md5" : "630005b2a1f92594fe8c730ad75aa5be", "matches" : [ { "signature" : { "accession" : "SM00051", "name" : "dsl11", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001774", "name" : "DSL", "description" : "Delta/Serrate/lag-2 (DSL) protein", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "cell communication", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007154" } ], "pathwayXRefs" : [ { "name" : "Constitutive Signaling by NOTCH1 HD Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2691232" }, { "name" : "NOTCH2 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-2979096" }, { "name" : "Constitutive Signaling by NOTCH1 PEST Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2644606" }, { "name" : "NOTCH3 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-9013507" }, { "name" : "Activated NOTCH1 Transmits Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-2122948" }, { "name" : "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant", "databaseName" : "Reactome", "id" : "R-HSA-2660826" }, { "name" : "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2894862" } ] } }, "locations" : [ { "start" : 184, "end" : 246, "hmmStart" : 1, "hmmEnd" : 66, "hmmLength" : 66, "hmmBounds" : "COMPLETE", "evalue" : 8.8E-25, "score" : 98.3, "location-fragments" : [ { "start" : 184, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-25, "score" : 98.3, "model-ac" : "SM00051" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 353, "end" : 389, "score" : 21.353, "alignment" : "ELNDCAhQPCLNGGTCKELGN--GYKCECPKNWLGAHCE", "location-fragments" : [ { "start" : 353, "end" : 389, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PR00010", "name" : "EGFBLOOD", "description" : "Type II EGF-like signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : null }, "locations" : [ { "start" : 403, "end" : 410, "pvalue" : 0.0152, "score" : 46.76, "motifNumber" : 2, "location-fragments" : [ { "start" : 403, "end" : 410, "dc-status" : "CONTINUOUS" } ] }, { "start" : 462, "end" : 468, "pvalue" : 0.0458, "score" : 48.57, "motifNumber" : 4, "location-fragments" : [ { "start" : 462, "end" : 468, "dc-status" : "CONTINUOUS" } ] }, { "start" : 353, "end" : 364, "pvalue" : 5.08E-4, "score" : 41.08, "motifNumber" : 1, "location-fragments" : [ { "start" : 353, "end" : 364, "dc-status" : "CONTINUOUS" } ] }, { "start" : 411, "end" : 421, "pvalue" : 6.74E-5, "score" : 50.59, "motifNumber" : 3, "location-fragments" : [ { "start" : 411, "end" : 421, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-5, "graphscan" : "IIII", "model-ac" : "PR00010" }, { "signature" : { "accession" : "G3DSA:2.10.25.140", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 205, "end" : 250, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 7.6E-21, "score" : 76.0, "envelopeStart" : 205, "envelopeEnd" : 250, "postProcessed" : true, "location-fragments" : [ { "start" : 205, "end" : 250, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.6E-21, "score" : 76.0, "model-ac" : "4xbmA02" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 469, "end" : 505, "score" : 23.593, "alignment" : "NNDDCHgNPCRNGGTCIDQVN--KFRCQCKPGFVGDLCE", "location-fragments" : [ { "start" : 469, "end" : 505, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS00022", "name" : "EGF_1", "description" : "EGF-like domain signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 493, "end" : 504, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I1M2I2M1I1M", "alignment" : "CqCkpGfvGDlC", "location-fragments" : [ { "start" : 493, "end" : 504, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00022" }, { "signature" : { "accession" : "PF07657", "name" : "MNNL", "description" : "N terminus of Notch ligand", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR011651", "name" : "Notch_ligand_N", "description" : "Notch ligand, N-terminal domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "multicellular organism development", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007275" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "Notch signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007219" } ], "pathwayXRefs" : [ { "name" : "Constitutive Signaling by NOTCH1 HD Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2691232" }, { "name" : "Activated NOTCH1 Transmits Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-2122948" }, { "name" : "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2894862" }, { "name" : "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant", "databaseName" : "Reactome", "id" : "R-HSA-2660826" }, { "name" : "NOTCH2 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-2979096" }, { "name" : "Constitutive Signaling by NOTCH1 PEST Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2644606" }, { "name" : "NOTCH3 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-9013507" } ] } }, "locations" : [ { "start" : 47, "end" : 118, "hmmStart" : 1, "hmmEnd" : 75, "hmmLength" : 75, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-26, "score" : 92.0, "envelopeStart" : 47, "envelopeEnd" : 118, "postProcessed" : true, "location-fragments" : [ { "start" : 47, "end" : 118, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-26, "score" : 92.0, "model-ac" : "PF07657" }, { "signature" : { "accession" : "PS00022", "name" : "EGF_1", "description" : "EGF-like domain signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 377, "end" : 388, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I1M2I2M1I1M", "alignment" : "CeCpkNwlGAhC", "location-fragments" : [ { "start" : 377, "end" : 388, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00022" }, { "signature" : { "accession" : "PTHR24044:SF422", "name" : "DELTA-LIKE PROTEIN B-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 37, "end" : 524, "hmmStart" : 11, "hmmEnd" : 477, "hmmLength" : 621, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 29, "envelopeEnd" : 526, "location-fragments" : [ { "start" : 37, "end" : 524, "dc-status" : "CONTINUOUS" } ] }, { "start" : 490, "end" : 659, "hmmStart" : 405, "hmmEnd" : 566, "hmmLength" : 621, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 489, "envelopeEnd" : 677, "location-fragments" : [ { "start" : 490, "end" : 659, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-191, "familyName" : "DELTA-LIKE PROTEIN B-RELATED", "score" : 641.2, "model-ac" : "PTHR24044:SF422" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 509, "end" : 542, "sites" : [ ], "evalue" : 1.30317E-6, "score" : 43.3942, "location-fragments" : [ { "start" : 509, "end" : 542, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PF12661", "name" : "hEGF", "description" : "Human growth factor-like EGF", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013032", "name" : "EGF-like_CS", "description" : "EGF-like, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 478, "end" : 499, "hmmStart" : 1, "hmmEnd" : 22, "hmmLength" : 22, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-7, "score" : 31.7, "envelopeStart" : 478, "envelopeEnd" : 499, "postProcessed" : true, "location-fragments" : [ { "start" : 478, "end" : 499, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-35, "score" : 119.1, "model-ac" : "PF12661" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 531, "end" : 542, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M4I1M", "alignment" : "CkCrpGFtgkdC", "location-fragments" : [ { "start" : 531, "end" : 542, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 395, "end" : 429, "hmmStart" : 3, "hmmEnd" : 36, "hmmLength" : 45, "hmmBounds" : "INCOMPLETE", "evalue" : 2.7E-11, "score" : 45.2, "envelopeStart" : 394, "envelopeEnd" : 430, "postProcessed" : true, "location-fragments" : [ { "start" : 395, "end" : 429, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-87, "score" : 287.7, "model-ac" : "3cfwA02" }, { "signature" : { "accession" : "PS01187", "name" : "EGF_CA", "description" : "Calcium-binding EGF-like domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018097", "name" : "EGF_Ca-bd_CS", "description" : "EGF-like calcium-binding, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 545, "end" : 569, "level" : "STRONG", "cigarAlignment" : "1M1I3M4I1M5I1M1I1M4I1M1I1M", "alignment" : "DvNECasspCanggtCvNrvngFrC", "location-fragments" : [ { "start" : 545, "end" : 569, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01187" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 430, "end" : 470, "hmmStart" : 4, "hmmEnd" : 41, "hmmLength" : 45, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.4E-11, "score" : 44.9, "envelopeStart" : 429, "envelopeEnd" : 470, "postProcessed" : true, "location-fragments" : [ { "start" : 430, "end" : 470, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-84, "score" : 279.2, "model-ac" : "1a3pA00" }, { "signature" : { "accession" : "PS00022", "name" : "EGF_1", "description" : "EGF-like domain signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 415, "end" : 426, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I1M2I2M1I1M", "alignment" : "CqCapGytGTdC", "location-fragments" : [ { "start" : 415, "end" : 426, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00022" }, { "signature" : { "accession" : "PF00008", "name" : "EGF", "description" : "EGF-like domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 433, "end" : 463, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 32, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.9E-7, "score" : 30.6, "envelopeStart" : 433, "envelopeEnd" : 465, "postProcessed" : true, "location-fragments" : [ { "start" : 433, "end" : 463, "dc-status" : "CONTINUOUS" } ] }, { "start" : 317, "end" : 349, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-7, "score" : 30.6, "envelopeStart" : 317, "envelopeEnd" : 349, "postProcessed" : true, "location-fragments" : [ { "start" : 317, "end" : 349, "dc-status" : "CONTINUOUS" } ] }, { "start" : 511, "end" : 540, "hmmStart" : 1, "hmmEnd" : 31, "hmmLength" : 32, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 8.8E-9, "score" : 35.5, "envelopeStart" : 511, "envelopeEnd" : 541, "postProcessed" : true, "location-fragments" : [ { "start" : 511, "end" : 540, "dc-status" : "CONTINUOUS" } ] }, { "start" : 357, "end" : 383, "hmmStart" : 1, "hmmEnd" : 28, "hmmLength" : 32, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.8E-6, "score" : 27.5, "envelopeStart" : 357, "envelopeEnd" : 387, "postProcessed" : true, "location-fragments" : [ { "start" : 357, "end" : 383, "dc-status" : "CONTINUOUS" } ] }, { "start" : 395, "end" : 423, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 32, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 9.0E-9, "score" : 35.5, "envelopeStart" : 395, "envelopeEnd" : 425, "postProcessed" : true, "location-fragments" : [ { "start" : 395, "end" : 423, "dc-status" : "CONTINUOUS" } ] }, { "start" : 549, "end" : 578, "hmmStart" : 1, "hmmEnd" : 31, "hmmLength" : 32, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.8E-8, "score" : 33.1, "envelopeStart" : 549, "envelopeEnd" : 579, "postProcessed" : true, "location-fragments" : [ { "start" : 549, "end" : 578, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-52, "score" : 173.5, "model-ac" : "PF00008" }, { "signature" : { "accession" : "PS00022", "name" : "EGF_1", "description" : "EGF-like domain signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 569, "end" : 580, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I1M2I2M1I1M", "alignment" : "CdCadGfsGSlC", "location-fragments" : [ { "start" : 569, "end" : 580, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00022" }, { "signature" : { "accession" : "PS00022", "name" : "EGF_1", "description" : "EGF-like domain signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 455, "end" : 466, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I1M2I2M1I1M", "alignment" : "CaCpsGfsGLkC", "location-fragments" : [ { "start" : 455, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00022" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 560, "end" : 571, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CvNrvngFrCdC", "location-fragments" : [ { "start" : 560, "end" : 571, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "SM00179", "name" : "egfca_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001881", "name" : "EGF-like_Ca-bd_dom", "description" : "EGF-like calcium-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 430, "end" : 467, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 0.058, "score" : 11.8, "location-fragments" : [ { "start" : 430, "end" : 467, "dc-status" : "CONTINUOUS" } ] }, { "start" : 507, "end" : 543, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-4, "score" : 31.6, "location-fragments" : [ { "start" : 507, "end" : 543, "dc-status" : "CONTINUOUS" } ] }, { "start" : 313, "end" : 351, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 6.2E-11, "score" : 52.3, "location-fragments" : [ { "start" : 313, "end" : 351, "dc-status" : "CONTINUOUS" } ] }, { "start" : 469, "end" : 505, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-8, "score" : 44.4, "location-fragments" : [ { "start" : 469, "end" : 505, "dc-status" : "CONTINUOUS" } ] }, { "start" : 353, "end" : 389, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 5.2E-6, "score" : 36.0, "location-fragments" : [ { "start" : 353, "end" : 389, "dc-status" : "CONTINUOUS" } ] }, { "start" : 545, "end" : 581, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-13, "score" : 60.8, "location-fragments" : [ { "start" : 545, "end" : 581, "dc-status" : "CONTINUOUS" } ] }, { "start" : 395, "end" : 427, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 0.003, "score" : 22.1, "location-fragments" : [ { "start" : 395, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-73, "score" : 259.0, "model-ac" : "SM00179" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 355, "end" : 389, "sites" : [ ], "evalue" : 1.86535E-5, "score" : 40.3126, "location-fragments" : [ { "start" : 355, "end" : 389, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 313, "end" : 353, "hmmStart" : 9, "hmmEnd" : 50, "hmmLength" : 53, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.4E-12, "score" : 47.7, "envelopeStart" : 308, "envelopeEnd" : 353, "postProcessed" : true, "location-fragments" : [ { "start" : 313, "end" : 353, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-85, "score" : 281.3, "model-ac" : "1eqgA01" }, { "signature" : { "accession" : "PS00022", "name" : "EGF_1", "description" : "EGF-like domain signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 268, "end" : 279, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I1M2I2M1I1M", "alignment" : "ClChsGwkGRlC", "location-fragments" : [ { "start" : 268, "end" : 279, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00022" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 391, "end" : 427, "score" : 20.335, "alignment" : "STMSCDdRPCHHGGTCLPTAH--GYTCQCAPGYTGTDCQ", "location-fragments" : [ { "start" : 391, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 512, "end" : 547, "hmmStart" : 2, "hmmEnd" : 39, "hmmLength" : 42, "hmmBounds" : "INCOMPLETE", "evalue" : 1.0E-11, "score" : 46.6, "envelopeStart" : 508, "envelopeEnd" : 548, "postProcessed" : true, "location-fragments" : [ { "start" : 512, "end" : 547, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-85, "score" : 283.0, "model-ac" : "2flbL01" }, { "signature" : { "accession" : "PF01414", "name" : "DSL", "description" : "Delta serrate ligand", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001774", "name" : "DSL", "description" : "Delta/Serrate/lag-2 (DSL) protein", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "cell communication", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007154" } ], "pathwayXRefs" : [ { "name" : "Constitutive Signaling by NOTCH1 HD Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2691232" }, { "name" : "NOTCH2 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-2979096" }, { "name" : "Constitutive Signaling by NOTCH1 PEST Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2644606" }, { "name" : "NOTCH3 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-9013507" }, { "name" : "Activated NOTCH1 Transmits Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-2122948" }, { "name" : "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant", "databaseName" : "Reactome", "id" : "R-HSA-2660826" }, { "name" : "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2894862" } ] } }, "locations" : [ { "start" : 184, "end" : 246, "hmmStart" : 1, "hmmEnd" : 63, "hmmLength" : 63, "hmmBounds" : "COMPLETE", "evalue" : 3.4E-24, "score" : 84.7, "envelopeStart" : 184, "envelopeEnd" : 246, "postProcessed" : true, "location-fragments" : [ { "start" : 184, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-24, "score" : 84.7, "model-ac" : "PF01414" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 339, "end" : 350, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M4I1M", "alignment" : "CsCppGFagenC", "location-fragments" : [ { "start" : 339, "end" : 350, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS00022", "name" : "EGF_1", "description" : "EGF-like domain signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 339, "end" : 350, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I1M2I2M1I1M", "alignment" : "CsCppGfaGEnC", "location-fragments" : [ { "start" : 339, "end" : 350, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00022" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 355, "end" : 394, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 52, "hmmBounds" : "COMPLETE", "evalue" : 3.8E-12, "score" : 47.7, "envelopeStart" : 355, "envelopeEnd" : 394, "postProcessed" : true, "location-fragments" : [ { "start" : 355, "end" : 394, "dc-status" : "CONTINUOUS" } ] }, { "start" : 471, "end" : 511, "hmmStart" : 1, "hmmEnd" : 41, "hmmLength" : 52, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.1E-14, "score" : 55.7, "envelopeStart" : 471, "envelopeEnd" : 514, "postProcessed" : true, "location-fragments" : [ { "start" : 471, "end" : 511, "dc-status" : "CONTINUOUS" } ] }, { "start" : 548, "end" : 594, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 52, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 8.5E-15, "score" : 56.1, "envelopeStart" : 547, "envelopeEnd" : 594, "postProcessed" : true, "location-fragments" : [ { "start" : 548, "end" : 594, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-87, "score" : 289.5, "model-ac" : "4d0eA03" }, { "signature" : { "accession" : "SSF57184", "name" : "Growth factor receptor domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009030", "name" : "Growth_fac_rcpt_cys_sf", "description" : "Growth factor receptor cysteine-rich domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 457, "end" : 581, "hmmLength" : 155, "location-fragments" : [ { "start" : 457, "end" : 581, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.67E-13, "model-ac" : "0053854" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 435, "end" : 467, "sites" : [ ], "evalue" : 0.0011634, "score" : 34.9198, "location-fragments" : [ { "start" : 435, "end" : 467, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 507, "end" : 543, "score" : 17.76, "alignment" : "KVDCCLlAPCANGGTCIVLPN--DFQCKCRPGFTGKDCS", "location-fragments" : [ { "start" : 507, "end" : 543, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 415, "end" : 426, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M4I1M", "alignment" : "CqCapGYtgtdC", "location-fragments" : [ { "start" : 415, "end" : 426, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 313, "end" : 351, "score" : 24.762, "alignment" : "DLNYCTnhKPCRNGGTCFNTGQ-GSYTCSCPPGFAGENCE", "location-fragments" : [ { "start" : 313, "end" : 351, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 455, "end" : 466, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M4I1M", "alignment" : "CaCpsGFsglkC", "location-fragments" : [ { "start" : 455, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 545, "end" : 581, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 562, "end" : 562, "residue" : "N" }, { "start" : 545, "end" : 545, "residue" : "D" }, { "start" : 548, "end" : 548, "residue" : "E" } ] } ], "evalue" : 3.26871E-9, "score" : 50.713, "location-fragments" : [ { "start" : 545, "end" : 581, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 471, "end" : 505, "sites" : [ ], "evalue" : 1.42011E-7, "score" : 46.0906, "location-fragments" : [ { "start" : 471, "end" : 505, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 569, "end" : 580, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M4I1M", "alignment" : "CdCadGFsgslC", "location-fragments" : [ { "start" : 569, "end" : 580, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS00022", "name" : "EGF_1", "description" : "EGF-like domain signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 531, "end" : 542, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I1M2I2M1I1M", "alignment" : "CkCrpGftGKdC", "location-fragments" : [ { "start" : 531, "end" : 542, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00022" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 484, "end" : 495, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CiDqvnkFrCqC", "location-fragments" : [ { "start" : 484, "end" : 495, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PS51051", "name" : "DSL", "description" : "DSL domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001774", "name" : "DSL", "description" : "Delta/Serrate/lag-2 (DSL) protein", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "cell communication", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007154" } ], "pathwayXRefs" : [ { "name" : "Constitutive Signaling by NOTCH1 HD Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2691232" }, { "name" : "NOTCH2 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-2979096" }, { "name" : "Constitutive Signaling by NOTCH1 PEST Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2644606" }, { "name" : "NOTCH3 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-9013507" }, { "name" : "Activated NOTCH1 Transmits Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-2122948" }, { "name" : "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant", "databaseName" : "Reactome", "id" : "R-HSA-2660826" }, { "name" : "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2894862" } ] } }, "locations" : [ { "start" : 202, "end" : 246, "score" : 15.945, "alignment" : "VTCDPHYYGNGCANLCRPRDDKFGHYSCSLQGDRVCLPGWKGDYC", "location-fragments" : [ { "start" : 202, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51051" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 399, "end" : 427, "sites" : [ ], "evalue" : 4.19092E-6, "score" : 41.8534, "location-fragments" : [ { "start" : 399, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 545, "end" : 581, "score" : 23.134, "alignment" : "DVNECAsSPCANGGTCVNRVN--GFRCDCADGFSGSLCK", "location-fragments" : [ { "start" : 545, "end" : 581, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR24044", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 490, "end" : 659, "hmmStart" : 405, "hmmEnd" : 566, "hmmLength" : 621, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 489, "envelopeEnd" : 677, "location-fragments" : [ { "start" : 490, "end" : 659, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-191, "familyName" : "DELTA-LIKE PROTEIN B-RELATED", "score" : 641.2, "model-ac" : "PTHR24044" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 247, "end" : 280, "score" : 7.408, "alignment" : "TKPICLPGCDDqHGHCSKPGE-----CLCHSGWKGRLCD", "location-fragments" : [ { "start" : 247, "end" : 280, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "G3DSA:2.60.40.3510", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 46, "end" : 204, "hmmStart" : 1, "hmmEnd" : 159, "hmmLength" : 159, "hmmBounds" : "COMPLETE", "evalue" : 2.6E-56, "score" : 191.6, "envelopeStart" : 46, "envelopeEnd" : 204, "postProcessed" : true, "location-fragments" : [ { "start" : 46, "end" : 204, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-56, "score" : 191.6, "model-ac" : "4xbmA01" }, { "signature" : { "accession" : "PTHR24044", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 37, "end" : 524, "hmmStart" : 11, "hmmEnd" : 477, "hmmLength" : 621, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 29, "envelopeEnd" : 526, "location-fragments" : [ { "start" : 37, "end" : 524, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-191, "familyName" : "DELTA-LIKE PROTEIN B-RELATED", "score" : 641.2, "model-ac" : "PTHR24044" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 493, "end" : 504, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M4I1M", "alignment" : "CqCkpGFvgdlC", "location-fragments" : [ { "start" : 493, "end" : 504, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 313, "end" : 351, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 316, "end" : 316, "residue" : "Y" }, { "start" : 313, "end" : 313, "residue" : "D" }, { "start" : 331, "end" : 331, "residue" : "N" } ] } ], "evalue" : 3.78573E-9, "score" : 50.713, "location-fragments" : [ { "start" : 313, "end" : 351, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 251, "end" : 312, "hmmStart" : 1, "hmmEnd" : 66, "hmmLength" : 66, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 9.2E-23, "score" : 82.2, "envelopeStart" : 251, "envelopeEnd" : 316, "postProcessed" : true, "location-fragments" : [ { "start" : 251, "end" : 312, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-45, "score" : 154.9, "model-ac" : "4xbmA03" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 429, "end" : 467, "score" : 21.066, "alignment" : "LKDHCNpSPCANGGTCSVLAGNAGYTCACPSGFSGLKCE", "location-fragments" : [ { "start" : 429, "end" : 467, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SSF57184", "name" : "Growth factor receptor domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009030", "name" : "Growth_fac_rcpt_cys_sf", "description" : "Growth factor receptor cysteine-rich domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 341, "end" : 474, "hmmLength" : 155, "location-fragments" : [ { "start" : 341, "end" : 474, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.51E-11, "model-ac" : "0053854" }, { "signature" : { "accession" : "SSF57196", "name" : "EGF/Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 315, "end" : 353, "hmmLength" : 54, "location-fragments" : [ { "start" : 315, "end" : 353, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.11E-7, "model-ac" : "0048718" }, { "signature" : { "accession" : "SM00181", "name" : "egf_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 281, "end" : 311, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.79, "score" : 18.8, "location-fragments" : [ { "start" : 281, "end" : 311, "dc-status" : "CONTINUOUS" } ] }, { "start" : 548, "end" : 581, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-8, "score" : 44.1, "location-fragments" : [ { "start" : 548, "end" : 581, "dc-status" : "CONTINUOUS" } ] }, { "start" : 510, "end" : 543, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-4, "score" : 31.1, "location-fragments" : [ { "start" : 510, "end" : 543, "dc-status" : "CONTINUOUS" } ] }, { "start" : 472, "end" : 505, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-7, "score" : 41.2, "location-fragments" : [ { "start" : 472, "end" : 505, "dc-status" : "CONTINUOUS" } ] }, { "start" : 356, "end" : 389, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-6, "score" : 36.8, "location-fragments" : [ { "start" : 356, "end" : 389, "dc-status" : "CONTINUOUS" } ] }, { "start" : 250, "end" : 280, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 5.3, "score" : 16.0, "location-fragments" : [ { "start" : 250, "end" : 280, "dc-status" : "CONTINUOUS" } ] }, { "start" : 203, "end" : 247, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 82.0, "score" : 5.5, "location-fragments" : [ { "start" : 203, "end" : 247, "dc-status" : "CONTINUOUS" } ] }, { "start" : 316, "end" : 351, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 3.9E-7, "score" : 39.7, "location-fragments" : [ { "start" : 316, "end" : 351, "dc-status" : "CONTINUOUS" } ] }, { "start" : 394, "end" : 427, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-7, "score" : 41.0, "location-fragments" : [ { "start" : 394, "end" : 427, "dc-status" : "CONTINUOUS" } ] }, { "start" : 432, "end" : 467, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 3.5E-6, "score" : 36.5, "location-fragments" : [ { "start" : 432, "end" : 467, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.6E-89, "score" : 310.8, "model-ac" : "SM00181" } ], "xref" : [ { "name" : "XP_018909928.1 PREDICTED: neurogenic locus protein delta-like [Bemisia tabaci]", "id" : "XP_018909928.1" } ] },{ "sequence" : "MIRGGRRVEECSLYAVILSLLVYETGSFYVGGGSGSQGAPNSLGGFPTSSAPGGRLDPYFDPLTPHNVTALMGQSAFLSCRVRNLGNKTVSWIRHRDIHILSVGRNTYTSDQRFQAIHHPEYDEWTLVIKWAQLRDAGMYECQISTQPVLSYFVNLNVVVPTASIIGGPDLYVDKGSTINLTCTIRYSPEPPQYIHWYHHDEVISYNSVRGGISVITEKGEVTTSYLLIQNADLSDTGNYSCCPSNADGASVKVHVLNGERPAAMQTGSAGLSNSSMNIVALMLLCWIYSEVLERVQLNSCHHIR", "md5" : "db477ad593c15faf0a367e650471dc88", "matches" : [ { "signature" : { "accession" : "PTHR23279:SF40", "name" : "DEFECTIVE PROBOSCIS EXTENSION RESPONSE 10, ISOFORM A-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 158, "end" : 298, "hmmStart" : 165, "hmmEnd" : 305, "hmmLength" : 382, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 158, "envelopeEnd" : 303, "location-fragments" : [ { "start" : 158, "end" : 298, "dc-status" : "CONTINUOUS" } ] }, { "start" : 54, "end" : 159, "hmmStart" : 28, "hmmEnd" : 133, "hmmLength" : 382, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 33, "envelopeEnd" : 160, "location-fragments" : [ { "start" : 54, "end" : 159, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-140, "familyName" : "DEFECTIVE PROBOSCIS EXTENSION RESPONSE 10, ISOFORM A-RELATED", "score" : 470.4, "model-ac" : "PTHR23279:SF40" }, { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 55, "end" : 162, "hmmStart" : 5, "hmmEnd" : 109, "hmmLength" : 110, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-33, "score" : 115.4, "envelopeStart" : 55, "envelopeEnd" : 162, "postProcessed" : true, "location-fragments" : [ { "start" : 55, "end" : 162, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-44, "score" : 152.7, "model-ac" : "5eo9A00" }, { "signature" : { "accession" : "SM00406", "name" : "igv1_8", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013106", "name" : "Ig_V-set", "description" : "Immunoglobulin V-set domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 178, "end" : 244, "hmmStart" : 1, "hmmEnd" : 76, "hmmLength" : 76, "hmmBounds" : "COMPLETE", "evalue" : 0.042, "score" : 18.5, "location-fragments" : [ { "start" : 178, "end" : 244, "dc-status" : "CONTINUOUS" } ] }, { "start" : 75, "end" : 144, "hmmStart" : 1, "hmmEnd" : 76, "hmmLength" : 76, "hmmBounds" : "COMPLETE", "evalue" : 0.18, "score" : 12.1, "location-fragments" : [ { "start" : 75, "end" : 144, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-4, "score" : 30.6, "model-ac" : "SM00406" }, { "signature" : { "accession" : "PF07679", "name" : "I-set", "description" : "Immunoglobulin I-set domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013098", "name" : "Ig_I-set", "description" : "Immunoglobulin I-set", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 64, "end" : 147, "hmmStart" : 6, "hmmEnd" : 78, "hmmLength" : 90, "hmmBounds" : "INCOMPLETE", "evalue" : 5.6E-10, "score" : 39.1, "envelopeStart" : 58, "envelopeEnd" : 160, "postProcessed" : true, "location-fragments" : [ { "start" : 64, "end" : 147, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-21, "score" : 74.9, "model-ac" : "PF07679" }, { "signature" : { "accession" : "PTHR23279", "name" : "DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR037448", "name" : "Zig-8", "description" : "Zwei Ig domain protein zig-8", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 158, "end" : 298, "hmmStart" : 165, "hmmEnd" : 305, "hmmLength" : 382, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 158, "envelopeEnd" : 303, "location-fragments" : [ { "start" : 158, "end" : 298, "dc-status" : "CONTINUOUS" } ] }, { "start" : 54, "end" : 159, "hmmStart" : 28, "hmmEnd" : 133, "hmmLength" : 382, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 33, "envelopeEnd" : 160, "location-fragments" : [ { "start" : 54, "end" : 159, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-140, "familyName" : "DEFECTIVE PROBOSCIS EXTENSION RESPONSE 10, ISOFORM A-RELATED", "score" : 470.4, "model-ac" : "PTHR23279" }, { "signature" : { "accession" : "SSF48726", "name" : "Immunoglobulin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036179", "name" : "Ig-like_dom_sf", "description" : "Immunoglobulin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 167, "end" : 253, "hmmLength" : 124, "location-fragments" : [ { "start" : 167, "end" : 253, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.49E-16, "model-ac" : "0046713" }, { "signature" : { "accession" : "cd00096", "name" : "Ig", "description" : "Ig", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 179, "end" : 249, "sites" : [ ], "evalue" : 2.57003E-6, "score" : 42.6145, "location-fragments" : [ { "start" : 179, "end" : 249, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00096" }, { "signature" : { "accession" : "PS50835", "name" : "IG_LIKE", "description" : "Ig-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR007110", "name" : "Ig-like_dom", "description" : "Immunoglobulin-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 58, "end" : 145, "score" : 10.136, "alignment" : "PYFDPLTpHNVTALMGQSAFLSCRVRN-LGNKTVSWIRHRDihilsvgRNTYTSDQRFQAIhhpEYDEWTLVIKWAQLRDAGMYECQIS-------------", "location-fragments" : [ { "start" : 58, "end" : 145, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50835" }, { "signature" : { "accession" : "SSF48726", "name" : "Immunoglobulin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036179", "name" : "Ig-like_dom_sf", "description" : "Immunoglobulin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 58, "end" : 158, "hmmLength" : 104, "location-fragments" : [ { "start" : 58, "end" : 158, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.88E-16, "model-ac" : "0050900" }, { "signature" : { "accession" : "SM00408", "name" : "igc2_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003598", "name" : "Ig_sub2", "description" : "Immunoglobulin subtype 2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 71, "end" : 149, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 56, "hmmBounds" : "COMPLETE", "evalue" : 3.1E-6, "score" : 36.7, "location-fragments" : [ { "start" : 71, "end" : 149, "dc-status" : "CONTINUOUS" } ] }, { "start" : 174, "end" : 249, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 56, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-5, "score" : 34.8, "location-fragments" : [ { "start" : 174, "end" : 249, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-16, "score" : 71.5, "model-ac" : "SM00408" }, { "signature" : { "accession" : "PF13927", "name" : "Ig_3", "description" : "Immunoglobulin domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 173, "end" : 246, "hmmStart" : 13, "hmmEnd" : 79, "hmmLength" : 79, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.3E-11, "score" : 42.5, "envelopeStart" : 158, "envelopeEnd" : 246, "postProcessed" : true, "location-fragments" : [ { "start" : 173, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.9E-20, "score" : 71.0, "model-ac" : "PF13927" }, { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 166, "end" : 257, "hmmStart" : 10, "hmmEnd" : 100, "hmmLength" : 104, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-15, "score" : 59.6, "envelopeStart" : 166, "envelopeEnd" : 257, "postProcessed" : true, "location-fragments" : [ { "start" : 166, "end" : 257, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-27, "score" : 97.0, "model-ac" : "4u7mA01" }, { "signature" : { "accession" : "SM00409", "name" : "IG_3c", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003599", "name" : "Ig_sub", "description" : "Immunoglobulin subtype", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 65, "end" : 161, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 4.8E-8, "score" : 42.7, "location-fragments" : [ { "start" : 65, "end" : 161, "dc-status" : "CONTINUOUS" } ] }, { "start" : 168, "end" : 257, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 3.9E-9, "score" : 46.3, "location-fragments" : [ { "start" : 168, "end" : 257, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-22, "score" : 89.1, "model-ac" : "SM00409" }, { "signature" : { "accession" : "PS50835", "name" : "IG_LIKE", "description" : "Ig-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR007110", "name" : "Ig-like_dom", "description" : "Immunoglobulin-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 161, "end" : 253, "score" : 11.896, "alignment" : "PTASIIGgPDLYVDKGSTINLTCTIRYsPEPPQYIHWYHHDEVISYNSVRGGISVitekgEVTTSYLLIQNADLSDTGNYSCCPSN-----ADGASVK", "location-fragments" : [ { "start" : 161, "end" : 253, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50835" } ], "xref" : [ { "name" : "XP_018909923.1 PREDICTED: kin of IRRE-like protein 3 isoform X2 [Bemisia tabaci]", "id" : "XP_018909923.1" } ] },{ "sequence" : "MKQARGADLRNGALVIYESVPSASPPYVCYVTLPGGSCFGSFQNCPTKAEARRSAAKIALMNSVFNEHPCRKISDDFIEKAVAEARASFKGDPEEADNPNTGIGAFRFMLETNKERTMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVVAHYSNRALDDDMRSQMALDWIAREQENAGALGRELNQAERELETARLAGRELRFPKEKKDILMLAHNQVNGGSLSS", "md5" : "80029fc9ec4e46b0d728d5b202aff6a3", "matches" : [ { "signature" : { "accession" : "PF14954", "name" : "LIX1", "description" : "Limb expression 1", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR029270", "name" : "LIX1", "description" : "Limb expression 1", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 219, "hmmStart" : 31, "hmmEnd" : 249, "hmmLength" : 249, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.5E-125, "score" : 417.5, "envelopeStart" : 1, "envelopeEnd" : 219, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 219, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-125, "score" : 417.7, "model-ac" : "PF14954" }, { "signature" : { "accession" : "PTHR31139:SF3", "name" : "LIX1-LIKE PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 221, "hmmStart" : 110, "hmmEnd" : 330, "hmmLength" : 337, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 227, "location-fragments" : [ { "start" : 1, "end" : 221, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-137, "familyName" : "LIX1-LIKE PROTEIN", "score" : 461.4, "model-ac" : "PTHR31139:SF3" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 172, "end" : 199, "location-fragments" : [ { "start" : 172, "end" : 199, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR31139", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 221, "hmmStart" : 110, "hmmEnd" : 330, "hmmLength" : 337, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 227, "location-fragments" : [ { "start" : 1, "end" : 221, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-137, "familyName" : "LIX1-LIKE PROTEIN", "score" : 461.4, "model-ac" : "PTHR31139" }, { "signature" : { "accession" : "SSF54768", "name" : "dsRNA-binding domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 63, "hmmLength" : 128, "location-fragments" : [ { "start" : 14, "end" : 63, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.61E-5, "model-ac" : "0050560" } ], "xref" : [ { "name" : "XP_018910046.1 PREDICTED: LIX1-like protein [Bemisia tabaci]", "id" : "XP_018910046.1" } ] },{ "sequence" : "MEQLDKLLQAAILFFVILSTINIEALYTYGAASDIFGEGKSDKEILDNLLLATRYDKRLLPPVVGTLTVNMSVLLLSLASPDESSLKYEVEFLLQQQWYDPRLTYSNQSKYDFLNAIHHHSDIWLPDTYFIMHGDFKDPLIPVHFALRIYRNGTVNYLMRRHLILSCQGRLHIFPFDDPLCSFAMESISYEQSAITYVWKNDEDTLRKSPSLTTLNAYLIQNQTIACPTKASWRDLGEAFESGSGGSPRDCKCSLCQRRFEEQGNYSCLKVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVAQARRKEPPHPIRVAKTIDVIARITFPVAYSIFLIFFFIHYKGFQNNAEGIIIDSEPDAQPLKMPQPENTASTHQSNFDHQTTSHLSPFSSDTTPH", "md5" : "98259f89bdc7ecd7b1c4bcf391c61a93", "matches" : [ { "signature" : { "accession" : "G3DSA:1.20.58.390", "name" : "Glr4197 protein", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 278, "end" : 434, "hmmStart" : 2, "hmmEnd" : 136, "hmmLength" : 150, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.2E-38, "score" : 133.3, "envelopeStart" : 274, "envelopeEnd" : 434, "postProcessed" : true, "location-fragments" : [ { "start" : 278, "end" : 434, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-38, "score" : 134.2, "model-ac" : "2m6bA00" }, { "signature" : { "accession" : "PTHR18945", "name" : "NEUROTRANSMITTER GATED ION CHANNEL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 384, "end" : 423, "hmmStart" : 455, "hmmEnd" : 494, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 379, "envelopeEnd" : 429, "location-fragments" : [ { "start" : 384, "end" : 423, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-152, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 510.8, "model-ac" : "PTHR18945" }, { "signature" : { "accession" : "PTHR18945:SF819", "name" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 70, "end" : 376, "hmmStart" : 110, "hmmEnd" : 387, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 64, "envelopeEnd" : 384, "location-fragments" : [ { "start" : 70, "end" : 376, "dc-status" : "CONTINUOUS" } ] }, { "start" : 384, "end" : 423, "hmmStart" : 455, "hmmEnd" : 494, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 379, "envelopeEnd" : 429, "location-fragments" : [ { "start" : 384, "end" : 423, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-152, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 510.8, "model-ac" : "PTHR18945:SF819" }, { "signature" : { "accession" : "cd19049", "name" : "LGIC_TM_anion", "description" : "LGIC_TM_anion", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 281, "end" : 422, "sites" : [ { "description" : "pentamer interface", "numLocations" : 35, "siteLocations" : [ { "start" : 303, "end" : 303, "residue" : "L" }, { "start" : 357, "end" : 357, "residue" : "L" }, { "start" : 293, "end" : 293, "residue" : "L" }, { "start" : 284, "end" : 284, "residue" : "T" }, { "start" : 310, "end" : 310, "residue" : "A" }, { "start" : 299, "end" : 299, "residue" : "I" }, { "start" : 330, "end" : 330, "residue" : "R" }, { "start" : 296, "end" : 296, "residue" : "S" }, { "start" : 331, "end" : 331, "residue" : "S" }, { "start" : 292, "end" : 292, "residue" : "I" }, { "start" : 314, "end" : 314, "residue" : "I" }, { "start" : 295, "end" : 295, "residue" : "T" }, { "start" : 328, "end" : 328, "residue" : "G" }, { "start" : 313, "end" : 313, "residue" : "M" }, { "start" : 321, "end" : 321, "residue" : "N" }, { "start" : 407, "end" : 407, "residue" : "R" }, { "start" : 285, "end" : 285, "residue" : "T" }, { "start" : 312, "end" : 312, "residue" : "V" }, { "start" : 317, "end" : 317, "residue" : "T" }, { "start" : 364, "end" : 364, "residue" : "N" }, { "start" : 281, "end" : 281, "residue" : "F" }, { "start" : 309, "end" : 309, "residue" : "P" }, { "start" : 320, "end" : 320, "residue" : "L" }, { "start" : 316, "end" : 316, "residue" : "V" }, { "start" : 339, "end" : 339, "residue" : "L" }, { "start" : 302, "end" : 302, "residue" : "W" }, { "start" : 304, "end" : 304, "residue" : "E" }, { "start" : 307, "end" : 307, "residue" : "A" }, { "start" : 338, "end" : 338, "residue" : "N" }, { "start" : 361, "end" : 361, "residue" : "V" }, { "start" : 354, "end" : 354, "residue" : "Y" }, { "start" : 308, "end" : 308, "residue" : "V" }, { "start" : 365, "end" : 365, "residue" : "Y" }, { "start" : 350, "end" : 350, "residue" : "M" }, { "start" : 327, "end" : 327, "residue" : "N" } ] } ], "evalue" : 3.34194E-36, "score" : 127.568, "location-fragments" : [ { "start" : 281, "end" : 422, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd19049" }, { "signature" : { "accession" : "PF02931", "name" : "Neur_chan_LBD", "description" : "Neurotransmitter-gated ion-channel ligand binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006202", "name" : "Neur_chan_lig-bd", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 210, "hmmStart" : 3, "hmmEnd" : 169, "hmmLength" : 217, "hmmBounds" : "INCOMPLETE", "evalue" : 7.3E-31, "score" : 107.3, "envelopeStart" : 42, "envelopeEnd" : 233, "postProcessed" : true, "location-fragments" : [ { "start" : 44, "end" : 210, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-31, "score" : 107.9, "model-ac" : "PF02931" }, { "signature" : { "accession" : "PTHR18945:SF819", "name" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 23, "end" : 63, "hmmStart" : 38, "hmmEnd" : 78, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 66, "location-fragments" : [ { "start" : 23, "end" : 63, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-152, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 510.8, "model-ac" : "PTHR18945:SF819" }, { "signature" : { "accession" : "PTHR18945", "name" : "NEUROTRANSMITTER GATED ION CHANNEL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 70, "end" : 376, "hmmStart" : 110, "hmmEnd" : 387, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 64, "envelopeEnd" : 384, "location-fragments" : [ { "start" : 70, "end" : 376, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-152, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 510.8, "model-ac" : "PTHR18945" }, { "signature" : { "accession" : "cd18987", "name" : "LGIC_ECD_anion", "description" : "LGIC_ECD_anion", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 67, "end" : 278, "sites" : [ { "description" : "pentamer interface", "numLocations" : 30, "siteLocations" : [ { "start" : 160, "end" : 160, "residue" : "R" }, { "start" : 148, "end" : 148, "residue" : "R" }, { "start" : 134, "end" : 134, "residue" : "G" }, { "start" : 136, "end" : 136, "residue" : "F" }, { "start" : 93, "end" : 93, "residue" : "L" }, { "start" : 126, "end" : 126, "residue" : "P" }, { "start" : 144, "end" : 144, "residue" : "H" }, { "start" : 131, "end" : 131, "residue" : "I" }, { "start" : 85, "end" : 85, "residue" : "S" }, { "start" : 188, "end" : 188, "residue" : "I" }, { "start" : 139, "end" : 139, "residue" : "P" }, { "start" : 158, "end" : 158, "residue" : "L" }, { "start" : 79, "end" : 79, "residue" : "A" }, { "start" : 130, "end" : 130, "residue" : "F" }, { "start" : 77, "end" : 77, "residue" : "S" }, { "start" : 128, "end" : 128, "residue" : "T" }, { "start" : 96, "end" : 96, "residue" : "Q" }, { "start" : 145, "end" : 145, "residue" : "F" }, { "start" : 278, "end" : 278, "residue" : "D" }, { "start" : 115, "end" : 115, "residue" : "N" }, { "start" : 117, "end" : 117, "residue" : "I" }, { "start" : 86, "end" : 86, "residue" : "L" }, { "start" : 138, "end" : 138, "residue" : "D" }, { "start" : 95, "end" : 95, "residue" : "Q" }, { "start" : 127, "end" : 127, "residue" : "D" }, { "start" : 118, "end" : 118, "residue" : "H" }, { "start" : 159, "end" : 159, "residue" : "M" }, { "start" : 80, "end" : 80, "residue" : "S" }, { "start" : 129, "end" : 129, "residue" : "Y" }, { "start" : 146, "end" : 146, "residue" : "A" } ] } ], "evalue" : 9.20048E-43, "score" : 147.825, "location-fragments" : [ { "start" : 67, "end" : 278, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18987" }, { "signature" : { "accession" : "PTHR18945", "name" : "NEUROTRANSMITTER GATED ION CHANNEL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 23, "end" : 63, "hmmStart" : 38, "hmmEnd" : 78, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 66, "location-fragments" : [ { "start" : 23, "end" : 63, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-152, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 510.8, "model-ac" : "PTHR18945" }, { "signature" : { "accession" : "PF02932", "name" : "Neur_chan_memb", "description" : "Neurotransmitter-gated ion-channel transmembrane region", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006029", "name" : "Neurotrans-gated_channel_TM", "description" : "Neurotransmitter-gated ion-channel transmembrane domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 287, "end" : 373, "hmmStart" : 2, "hmmEnd" : 88, "hmmLength" : 238, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-12, "score" : 47.9, "envelopeStart" : 286, "envelopeEnd" : 382, "postProcessed" : true, "location-fragments" : [ { "start" : 287, "end" : 373, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-13, "score" : 51.7, "model-ac" : "PF02932" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 440, "end" : 480, "location-fragments" : [ { "start" : 440, "end" : 480, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 449, "end" : 480, "location-fragments" : [ { "start" : 449, "end" : 480, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF90112", "name" : "Neurotransmitter-gated ion-channel transmembrane pore", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036719", "name" : "Neuro-gated_channel_TM_sf", "description" : "Neurotransmitter-gated ion-channel transmembrane domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 281, "end" : 426, "hmmLength" : 227, "location-fragments" : [ { "start" : 281, "end" : 426, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.83E-25, "model-ac" : "0041810" }, { "signature" : { "accession" : "PR00253", "name" : "GABAARECEPTR", "description" : "Gamma-aminobutyric acid A (GABAA) receptor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR006028", "name" : "GABAA/Glycine_rcpt", "description" : "Gamma-aminobutyric acid A receptor/Glycine receptor alpha", "type" : "FAMILY", "goXRefs" : [ { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 405, "end" : 425, "pvalue" : 2.76E-6, "score" : 34.22, "motifNumber" : 4, "location-fragments" : [ { "start" : 405, "end" : 425, "dc-status" : "CONTINUOUS" } ] }, { "start" : 282, "end" : 302, "pvalue" : 1.01E-5, "score" : 29.84, "motifNumber" : 1, "location-fragments" : [ { "start" : 282, "end" : 302, "dc-status" : "CONTINUOUS" } ] }, { "start" : 342, "end" : 363, "pvalue" : 1.31E-8, "score" : 35.36, "motifNumber" : 3, "location-fragments" : [ { "start" : 342, "end" : 363, "dc-status" : "CONTINUOUS" } ] }, { "start" : 308, "end" : 329, "pvalue" : 5.61E-10, "score" : 43.64, "motifNumber" : 2, "location-fragments" : [ { "start" : 308, "end" : 329, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-22, "graphscan" : "iIII", "model-ac" : "PR00253" }, { "signature" : { "accession" : "SSF63712", "name" : "Nicotinic receptor ligand binding domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036734", "name" : "Neur_chan_lig-bd_sf", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 230, "hmmLength" : 205, "location-fragments" : [ { "start" : 42, "end" : 230, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.44E-35, "model-ac" : "0038932" } ], "xref" : [ { "name" : "XP_018910336.1 PREDICTED: glutamate-gated chloride channel isoform X7 [Bemisia tabaci]", "id" : "XP_018910336.1" } ] },{ "sequence" : "MYLITIIIIRQHFEIPLLIIGIMKELTRLYAVLLFPPEKGTEEETVNVVPQSWVKKEGKICLWPKIKNPKKLIEECTSPVDVACEWQEFEYKAKCKENIEGYSKAKIVEKNVLDEKESNLSEISDVPKKRPRMPKNPFSPSAMQSTSSSPKSCVSLEEINDADVESEENTTPIRRRSFRQAQISPLPEDDSPVGSNQTLTPKYPTPPTKRVTPIRKSHCNASRSLFADGEGSAKNTKPPSNIRLVKTCKSHQNIAKEPSAQVSSNSDHKKSRQSHTSKTIAEESFTNPTPELSSSFFAHSDHEKSRQSHTSKTNAEECFMNPTSESSSSFFAHSDHEKSRQSHTSKTNAEECFMSPTSESSSGPSASLDFSNLFMPTSKSLTTFHTQWRKMNAQQKDLYQAETLFVLRRTLPLMVTKLGPGIPGTSAAIDSIKAHPNLTCFPINDEDDLNKAEKLLKMKGWKQKLETLLLSKKCKDLRETARAMCSFLFTDQFGSGYSMVGQKKKKSFVQLPLVTLLKKTISSAFNTKNKITITDEEINEAVEAWLKYCKNHLTQVNGNFPLNLNFSVAVSRKIQFASSWQLLFLE", "md5" : "ae70536c8f9fa6e28453e893b7363179", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 278, "end" : 296, "location-fragments" : [ { "start" : 278, "end" : 296, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 138, "end" : 155, "location-fragments" : [ { "start" : 138, "end" : 155, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 346, "end" : 360, "location-fragments" : [ { "start" : 346, "end" : 360, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 189, "end" : 205, "location-fragments" : [ { "start" : 189, "end" : 205, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF16064", "name" : "DUF4806", "description" : "Domain of unknown function (DUF4806)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR032071", "name" : "DUF4806", "description" : "Domain of unknown function DUF4806", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 441, "end" : 509, "hmmStart" : 7, "hmmEnd" : 78, "hmmLength" : 90, "hmmBounds" : "INCOMPLETE", "evalue" : 9.9E-6, "score" : 25.8, "envelopeStart" : 437, "envelopeEnd" : 524, "postProcessed" : true, "location-fragments" : [ { "start" : 441, "end" : 509, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-6, "score" : 27.4, "model-ac" : "PF16064" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 234, "end" : 267, "location-fragments" : [ { "start" : 234, "end" : 267, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 331, "end" : 345, "location-fragments" : [ { "start" : 331, "end" : 345, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 297, "end" : 311, "location-fragments" : [ { "start" : 297, "end" : 311, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 119, "end" : 360, "location-fragments" : [ { "start" : 119, "end" : 360, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 312, "end" : 330, "location-fragments" : [ { "start" : 312, "end" : 330, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910539.1 PREDICTED: uncharacterized protein LOC109039501 isoform X1 [Bemisia tabaci]", "id" : "XP_018910539.1" } ] },{ "sequence" : "MPLKDYEALVGSTAGIVTVASFFAPAFICKTVIKKGSTENVDPMPFIGGMSMSILMLQHGLILKDPAMIPVNVFGFILNLIYFSIYYHYSTERGQLWLTLGKAATFVAVLIGYAQWEYEHKVEFRFGLITTSIMFALISAPLLSLGEIIRTKNSASLPFPLIVSSLFVTSLWLLYGIIIENIFVQFQNAVAFLLCLGQLILCIIYPARDDSKDKAKKAE", "md5" : "dbc2c1363b5cc714ea66e6e43a499404", "matches" : [ { "signature" : { "accession" : "PF03083", "name" : "MtN3_slv", "description" : "Sugar efflux transporter for intercellular exchange", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004316", "name" : "SWEET_sugar_transpr", "description" : "SWEET sugar transporter", "type" : "FAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ { "name" : "Cellular hexose transport", "databaseName" : "Reactome", "id" : "R-HSA-189200" } ] } }, "locations" : [ { "start" : 9, "end" : 92, "hmmStart" : 2, "hmmEnd" : 85, "hmmLength" : 87, "hmmBounds" : "INCOMPLETE", "evalue" : 2.8E-19, "score" : 68.9, "envelopeStart" : 8, "envelopeEnd" : 94, "postProcessed" : true, "location-fragments" : [ { "start" : 9, "end" : 92, "dc-status" : "CONTINUOUS" } ] }, { "start" : 125, "end" : 208, "hmmStart" : 2, "hmmEnd" : 85, "hmmLength" : 87, "hmmBounds" : "INCOMPLETE", "evalue" : 1.3E-15, "score" : 57.2, "envelopeStart" : 124, "envelopeEnd" : 210, "postProcessed" : true, "location-fragments" : [ { "start" : 125, "end" : 208, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-35, "score" : 121.2, "model-ac" : "PF03083" }, { "signature" : { "accession" : "G3DSA:1.20.1280.290", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 4, "end" : 94, "hmmStart" : 8, "hmmEnd" : 89, "hmmLength" : 94, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-12, "score" : 49.9, "envelopeStart" : 4, "envelopeEnd" : 94, "postProcessed" : true, "location-fragments" : [ { "start" : 4, "end" : 94, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-25, "score" : 89.0, "model-ac" : "4rngC00" }, { "signature" : { "accession" : "PTHR10791:SF5", "name" : "SUGAR TRANSPORTER SWEET", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 217, "hmmStart" : 13, "hmmEnd" : 226, "hmmLength" : 228, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 219, "location-fragments" : [ { "start" : 8, "end" : 217, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-61, "familyName" : "SUGAR TRANSPORTER SWEET", "score" : 210.9, "model-ac" : "PTHR10791:SF5" }, { "signature" : { "accession" : "PTHR10791", "name" : "RAG1-ACTIVATING PROTEIN 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 217, "hmmStart" : 13, "hmmEnd" : 226, "hmmLength" : 228, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 219, "location-fragments" : [ { "start" : 8, "end" : 217, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-61, "familyName" : "SUGAR TRANSPORTER SWEET", "score" : 210.9, "model-ac" : "PTHR10791" }, { "signature" : { "accession" : "G3DSA:1.20.1280.290", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 124, "end" : 218, "hmmStart" : 8, "hmmEnd" : 87, "hmmLength" : 100, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-12, "score" : 48.3, "envelopeStart" : 124, "envelopeEnd" : 218, "postProcessed" : true, "location-fragments" : [ { "start" : 124, "end" : 218, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.7E-26, "score" : 91.9, "model-ac" : "4x5mA00" } ], "xref" : [ { "name" : "XP_018909669.1 PREDICTED: sugar transporter SWEET1-like [Bemisia tabaci]", "id" : "XP_018909669.1" }, { "name" : "XP_018909668.1 PREDICTED: sugar transporter SWEET1-like [Bemisia tabaci]", "id" : "XP_018909668.1" }, { "name" : "XP_018909670.1 PREDICTED: sugar transporter SWEET1-like [Bemisia tabaci]", "id" : "XP_018909670.1" }, { "name" : "XP_018909667.1 PREDICTED: sugar transporter SWEET1-like [Bemisia tabaci]", "id" : "XP_018909667.1" } ] },{ "sequence" : "MSALPYFGLLLALVIQSMVAMDPGGQERRPQRSQSVLQKMRNVIRVADSDPCLDLGEQKIQRKNWEEIAEKSALCQAAFDDLMSLPDDLKGPCLGACRAECQLKKKKSGQWFQCTVLKPSHCFCTPSTKPFAFCASSVALEIQRNQDAPAPGRTLYQALSANRRGGGGAN", "md5" : "ae13cb3439454aad75f1281c8504a3f6", "matches" : [ ], "xref" : [ { "name" : "XP_018909947.1 PREDICTED: uncharacterized protein LOC109039070 isoform X1 [Bemisia tabaci]", "id" : "XP_018909947.1" } ] },{ "sequence" : "MLSITKVLIVILISFMFLRVDSQRPLATWLTEDGKLPRYKDGKPIGPSVAQPVVFSAAQPSGGGLTIGNYLGALRHWAKLQKDYDCIFCIADLHAITKHQEPAELRKATLDTLAIYLASGITPKKSTIFLQSQVPEHAQLAWVLNNYAYVGELNRMTQFKEKSVNHGETITAGLFEYPVLMAADILLYQANKVPVGLDQKQHLELCRDIAKRFNLAYDTDLFQIPEPLVPAGAEGSRVMSLLNATKKMSKSDPNPNNAIFLLDDPAVAAKKIKGAVTDSDNPPVVRFDVVKKPGISNLIQIVAGITDSSISEVEEMTKGFNYGRFKSQAAEDVLYWLQNFQEDYRRYRENITYLQEILQEGREFAHKKAQKTLYQVFEKVGFITTHVVF", "md5" : "7d9aef4d9de5b751c635200a127190df", "matches" : [ { "signature" : { "accession" : "PTHR43766:SF2", "name" : "TRYPTOPHAN--TRNA LIGASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 52, "end" : 384, "hmmStart" : 3, "hmmEnd" : 333, "hmmLength" : 335, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 50, "envelopeEnd" : 386, "location-fragments" : [ { "start" : 52, "end" : 384, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-121, "familyName" : "TRYPTOPHAN--TRNA LIGASE", "score" : 408.0, "model-ac" : "PTHR43766:SF2" }, { "signature" : { "accession" : "PF00579", "name" : "tRNA-synt_1b", "description" : "tRNA synthetases class I (W and Y)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002305", "name" : "aa-tRNA-synth_Ic", "description" : "Aminoacyl-tRNA synthetase, class Ic", "type" : "FAMILY", "goXRefs" : [ { "name" : "tRNA aminoacylation for protein translation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006418" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "nucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0000166" }, { "name" : "aminoacyl-tRNA ligase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004812" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 53, "end" : 332, "hmmStart" : 7, "hmmEnd" : 287, "hmmLength" : 293, "hmmBounds" : "INCOMPLETE", "evalue" : 3.9E-77, "score" : 259.5, "envelopeStart" : 49, "envelopeEnd" : 338, "postProcessed" : true, "location-fragments" : [ { "start" : 53, "end" : 332, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-77, "score" : 260.2, "model-ac" : "PF00579" }, { "signature" : { "accession" : "PTHR43766", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 52, "end" : 384, "hmmStart" : 3, "hmmEnd" : 333, "hmmLength" : 335, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 50, "envelopeEnd" : 386, "location-fragments" : [ { "start" : 52, "end" : 384, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-121, "familyName" : "TRYPTOPHAN--TRNA LIGASE", "score" : 408.0, "model-ac" : "PTHR43766" }, { "signature" : { "accession" : "SSF52374", "name" : "Nucleotidylyl transferase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 53, "end" : 382, "hmmLength" : 326, "location-fragments" : [ { "start" : 53, "end" : 382, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.06E-82, "model-ac" : "0046259" }, { "signature" : { "accession" : "G3DSA:1.10.240.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 238, "end" : 350, "hmmStart" : 1, "hmmEnd" : 324, "hmmLength" : 113, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-125, "score" : 420.4, "envelopeStart" : 54, "envelopeEnd" : 381, "postProcessed" : true, "location-fragments" : [ { "start" : 238, "end" : 350, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-125, "score" : 420.6, "model-ac" : "3n9iA02" }, { "signature" : { "accession" : "PR01039", "name" : "TRNASYNTHTRP", "description" : "Tryptophanyl-tRNA synthetase signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002306", "name" : "Trp-tRNA-ligase", "description" : "Tryptophan-tRNA ligase", "type" : "FAMILY", "goXRefs" : [ { "name" : "tryptophanyl-tRNA aminoacylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006436" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "tryptophan-tRNA ligase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004830" }, { "name" : "nucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0000166" } ], "pathwayXRefs" : [ { "name" : "Aminoacyl-tRNA biosynthesis", "databaseName" : "KEGG", "id" : "00970+6.1.1.2" } ] } }, "locations" : [ { "start" : 65, "end" : 81, "pvalue" : 2.0E-6, "score" : 35.5, "motifNumber" : 1, "location-fragments" : [ { "start" : 65, "end" : 81, "dc-status" : "CONTINUOUS" } ] }, { "start" : 115, "end" : 134, "pvalue" : 2.07E-9, "score" : 45.0, "motifNumber" : 2, "location-fragments" : [ { "start" : 115, "end" : 134, "dc-status" : "CONTINUOUS" } ] }, { "start" : 247, "end" : 257, "pvalue" : 8.23E-6, "score" : 57.99, "motifNumber" : 4, "location-fragments" : [ { "start" : 247, "end" : 257, "dc-status" : "CONTINUOUS" } ] }, { "start" : 191, "end" : 212, "pvalue" : 5.27E-12, "score" : 55.49, "motifNumber" : 3, "location-fragments" : [ { "start" : 191, "end" : 212, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-25, "graphscan" : "IIII", "model-ac" : "PR01039" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 337, "end" : 357, "location-fragments" : [ { "start" : 337, "end" : 357, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "cd00806", "name" : "TrpRS_core", "description" : "TrpRS_core", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR002306", "name" : "Trp-tRNA-ligase", "description" : "Tryptophan-tRNA ligase", "type" : "FAMILY", "goXRefs" : [ { "name" : "tryptophanyl-tRNA aminoacylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006436" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "tryptophan-tRNA ligase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004830" }, { "name" : "nucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0000166" } ], "pathwayXRefs" : [ { "name" : "Aminoacyl-tRNA biosynthesis", "databaseName" : "KEGG", "id" : "00970+6.1.1.2" } ] } }, "locations" : [ { "start" : 54, "end" : 333, "sites" : [ { "description" : "HIGH motif", "numLocations" : 4, "siteLocations" : [ { "start" : 69, "end" : 69, "residue" : "N" }, { "start" : 68, "end" : 68, "residue" : "G" }, { "start" : 67, "end" : 67, "residue" : "I" }, { "start" : 66, "end" : 66, "residue" : "T" } ] }, { "description" : "dimer interface", "numLocations" : 21, "siteLocations" : [ { "start" : 150, "end" : 150, "residue" : "V" }, { "start" : 137, "end" : 137, "residue" : "H" }, { "start" : 154, "end" : 154, "residue" : "N" }, { "start" : 175, "end" : 175, "residue" : "F" }, { "start" : 97, "end" : 97, "residue" : "T" }, { "start" : 149, "end" : 149, "residue" : "Y" }, { "start" : 151, "end" : 151, "residue" : "G" }, { "start" : 96, "end" : 96, "residue" : "I" }, { "start" : 148, "end" : 148, "residue" : "A" }, { "start" : 180, "end" : 180, "residue" : "L" }, { "start" : 142, "end" : 142, "residue" : "W" }, { "start" : 153, "end" : 153, "residue" : "L" }, { "start" : 138, "end" : 138, "residue" : "A" }, { "start" : 176, "end" : 176, "residue" : "E" }, { "start" : 146, "end" : 146, "residue" : "N" }, { "start" : 93, "end" : 93, "residue" : "L" }, { "start" : 145, "end" : 145, "residue" : "N" }, { "start" : 173, "end" : 173, "residue" : "G" }, { "start" : 140, "end" : 140, "residue" : "L" }, { "start" : 141, "end" : 141, "residue" : "A" }, { "start" : 179, "end" : 179, "residue" : "V" } ] }, { "description" : "active site", "numLocations" : 25, "siteLocations" : [ { "start" : 131, "end" : 131, "residue" : "Q" }, { "start" : 193, "end" : 193, "residue" : "V" }, { "start" : 248, "end" : 248, "residue" : "M" }, { "start" : 184, "end" : 184, "residue" : "D" }, { "start" : 198, "end" : 198, "residue" : "D" }, { "start" : 59, "end" : 59, "residue" : "Q" }, { "start" : 55, "end" : 55, "residue" : "F" }, { "start" : 57, "end" : 57, "residue" : "A" }, { "start" : 72, "end" : 72, "residue" : "G" }, { "start" : 177, "end" : 177, "residue" : "Y" }, { "start" : 195, "end" : 195, "residue" : "V" }, { "start" : 237, "end" : 237, "residue" : "R" }, { "start" : 69, "end" : 69, "residue" : "N" }, { "start" : 247, "end" : 247, "residue" : "K" }, { "start" : 202, "end" : 202, "residue" : "H" }, { "start" : 199, "end" : 199, "residue" : "Q" }, { "start" : 94, "end" : 94, "residue" : "H" }, { "start" : 56, "end" : 56, "residue" : "S" }, { "start" : 58, "end" : 58, "residue" : "A" }, { "start" : 68, "end" : 68, "residue" : "G" }, { "start" : 181, "end" : 181, "residue" : "M" }, { "start" : 196, "end" : 196, "residue" : "G" }, { "start" : 250, "end" : 250, "residue" : "K" }, { "start" : 89, "end" : 89, "residue" : "C" }, { "start" : 66, "end" : 66, "residue" : "T" } ] }, { "description" : "KMSKS motif", "numLocations" : 5, "siteLocations" : [ { "start" : 251, "end" : 251, "residue" : "S" }, { "start" : 250, "end" : 250, "residue" : "K" }, { "start" : 247, "end" : 247, "residue" : "K" }, { "start" : 249, "end" : 249, "residue" : "S" }, { "start" : 248, "end" : 248, "residue" : "M" } ] } ], "evalue" : 2.16055E-120, "score" : 348.034, "location-fragments" : [ { "start" : 54, "end" : 333, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00806" }, { "signature" : { "accession" : "MF_00140_B", "name" : "Trp_tRNA_synth_B", "description" : "Tryptophan--tRNA ligase [trpS].", "signatureLibraryRelease" : { "library" : "HAMAP", "version" : "2020_01" }, "entry" : { "accession" : "IPR024109", "name" : "Trp-tRNA-ligase_bac-type", "description" : "Tryptophan-tRNA ligase, bacterial-type", "type" : "FAMILY", "goXRefs" : [ { "name" : "tryptophan-tRNA ligase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004830" } ], "pathwayXRefs" : [ { "name" : "Aminoacyl-tRNA biosynthesis", "databaseName" : "KEGG", "id" : "00970+6.1.1.2" }, { "name" : "Mitochondrial tRNA aminoacylation", "databaseName" : "Reactome", "id" : "R-HSA-379726" } ] } }, "locations" : [ { "start" : 51, "end" : 383, "score" : 38.642, "alignment" : "QPVVFSAAQPSGGgLTIGNYLGALRHWAKLQKDYDCIFCIADLHAITKHQEPAELRKATLDTLAIYLASGITPKKSTIFLQSQVPEHAQLAWVLNNYAYVGELNRMTQFKEKSVNHG-ETITAGLFEYPVLMAADILLYQANKVPVGLDQKQHLELCRDIAKRFNLAY-DTDLFQIPEPLVPAGaeGSRVMSLLNATKKMSKSDPNPNNAIFLLDDPAVAAKKIKGAVTDSDnpPVVRFDVVKKPGISNLIQIVAGIT-DSSISEVEEMTKGFNYGRFKSQAAEDVLYWLQNFQEDYRRYRENITYLQEILQEGREFAHKKAQKTLYQVFEKVGFI", "location-fragments" : [ { "start" : 51, "end" : 383, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "MF_00140_B" }, { "signature" : { "accession" : "TIGR00233", "name" : "TIGR00233", "description" : "trpS: tryptophan--tRNA ligase", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR002306", "name" : "Trp-tRNA-ligase", "description" : "Tryptophan-tRNA ligase", "type" : "FAMILY", "goXRefs" : [ { "name" : "tryptophanyl-tRNA aminoacylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006436" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "tryptophan-tRNA ligase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004830" }, { "name" : "nucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0000166" } ], "pathwayXRefs" : [ { "name" : "Aminoacyl-tRNA biosynthesis", "databaseName" : "KEGG", "id" : "00970+6.1.1.2" } ] } }, "locations" : [ { "start" : 52, "end" : 382, "hmmStart" : 3, "hmmEnd" : 328, "hmmLength" : 328, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 9.5E-101, "score" : 335.3, "envelopeStart" : 50, "envelopeEnd" : 382, "postProcessed" : false, "location-fragments" : [ { "start" : 52, "end" : 382, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-101, "score" : 335.5, "model-ac" : "TIGR00233" }, { "signature" : { "accession" : "PS00178", "name" : "AA_TRNA_LIGASE_I", "description" : "Aminoacyl-transfer RNA synthetases class-I signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR001412", "name" : "aa-tRNA-synth_I_CS", "description" : "Aminoacyl-tRNA synthetase, class I, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "tRNA aminoacylation for protein translation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006418" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "aminoacyl-tRNA ligase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004812" }, { "name" : "nucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0000166" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 60, "end" : 70, "level" : "STRONG", "cigarAlignment" : "1M1I2M1I6M", "alignment" : "PsGGgLTIGNY", "location-fragments" : [ { "start" : 60, "end" : 70, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00178" }, { "signature" : { "accession" : "G3DSA:3.40.50.620", "name" : "HUPs", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR014729", "name" : "Rossmann-like_a/b/a_fold", "description" : "Rossmann-like alpha/beta/alpha sandwich fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 54, "end" : 381, "hmmStart" : 1, "hmmEnd" : 324, "hmmLength" : 233, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.8E-125, "score" : 420.4, "envelopeStart" : 54, "envelopeEnd" : 381, "postProcessed" : true, "location-fragments" : [ { "start" : 54, "end" : 237, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 351, "end" : 381, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.5E-125, "score" : 420.6, "model-ac" : "3n9iA01" } ], "xref" : [ { "name" : "XP_018910012.1 PREDICTED: uncharacterized protein LOC109039114 isoform X1 [Bemisia tabaci]", "id" : "XP_018910012.1" } ] },{ "sequence" : "MTMRRITWHRLFLVFRYKLIYNRTTHRSHNQIGVKTRVVGKFGSLKPVEYLTNDPISHLGSHYFDDIAKSFRRSGYSDEHNLKAAAYDGRYAIPQLEDFGYFVNFTELVERTAHCSKRRVSIVTHSMGGLVAAYFLVNKTQAWKNKYIHNFIAISTPWLGSPKAIEAFVTGTNFDVKTFQLSIMRELVRTFQSVALLLPAENAYKETVLVDWPEQNKIYTGKDYKQLFTDMKYKDGYLMRRDVRSLMPVHGKKLGVKLVCVWSHFVKTPFTMHVEGHMANPKHVWRTDVDGDGTVTLESLEYCKRFPNVTTRVFPGKDHLKIVFSDGVIDYIKSNLVHAKPVLY", "md5" : "4b1c23b2836023244b7ba69f96c5d5a2", "matches" : [ { "signature" : { "accession" : "SSF53474", "name" : "alpha/beta-Hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 61, "end" : 325, "hmmLength" : 388, "location-fragments" : [ { "start" : 61, "end" : 325, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.96E-19, "model-ac" : "0047879" }, { "signature" : { "accession" : "PTHR11440", "name" : "LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 337, "hmmStart" : 103, "hmmEnd" : 418, "hmmLength" : 420, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 13, "envelopeEnd" : 339, "location-fragments" : [ { "start" : 18, "end" : 337, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-54, "familyName" : "GROUP XV PHOSPHOLIPASE A2", "score" : 186.5, "model-ac" : "PTHR11440" }, { "signature" : { "accession" : "PF02450", "name" : "LCAT", "description" : "Lecithin:cholesterol acyltransferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR003386", "name" : "LACT/PDAT_acylTrfase", "description" : "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "lipid metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006629" }, { "name" : "O-acyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008374" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 18, "end" : 224, "hmmStart" : 26, "hmmEnd" : 227, "hmmLength" : 392, "hmmBounds" : "INCOMPLETE", "evalue" : 8.6E-42, "score" : 143.7, "envelopeStart" : 10, "envelopeEnd" : 257, "postProcessed" : true, "location-fragments" : [ { "start" : 18, "end" : 224, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-44, "score" : 152.1, "model-ac" : "PF02450" }, { "signature" : { "accession" : "PTHR11440:SF47", "name" : "GROUP XV PHOSPHOLIPASE A2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 337, "hmmStart" : 103, "hmmEnd" : 418, "hmmLength" : 420, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 13, "envelopeEnd" : 339, "location-fragments" : [ { "start" : 18, "end" : 337, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-54, "familyName" : "GROUP XV PHOSPHOLIPASE A2", "score" : 186.5, "model-ac" : "PTHR11440:SF47" } ], "xref" : [ { "name" : "XP_018910489.1 PREDICTED: group XV phospholipase A2-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910489.1" } ] },{ "sequence" : "MSVAPTGLHDLSTPQVRKIPSSSGRSKTTSSTSNKPSSSLLINGGKKNIKKKSTVLSPSASPTTSSDRMMKKTQTNMTRSATATSNFSAPSRRIRKTALTSNDSDESSLLDASSSDIYSTPNEEDRKQTNGSAKLIVPSITRVSGNANVCRPSVSAQCAHR", "md5" : "451d301c86ff77221fa7e9f14e5ca5df", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 119, "location-fragments" : [ { "start" : 15, "end" : 119, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 134, "location-fragments" : [ { "start" : 1, "end" : 134, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910023.1 PREDICTED: putative protein TPRXL [Bemisia tabaci]", "id" : "XP_018910023.1" } ] },{ "sequence" : "MKYGTITLFLFTLPPLVVTNTNTPIKDPYGIDDRLEIVHLYPDQWPTGVAVSESGRIFSCFPAANDELNSNNGTNNVFQVAELTGFDTETAYPNETYNNPPGGCVNFSGPFPRTKGLSDYLLSVPTVAFDQNDVLYLLDNGRCIYNGVRLEASPGGPKLVAVDLNTDSVIRTYTFPTDVVTPESFLGDVEFDRQGYAYITDFSATGDNAIIVLNLDDGDSWRVLMRDASVVALPNFVPFVWGQSLYQVQSSGSGKIVGFESISIGVEGLTISNDFSTLYYTGTALRFLYTVPTDLLRNRSTPAIEIVAAVRVVTMQGVTPVIGIDDSGYIYSGNAEQSAITVYDTTTGYKIPFVRDKRIGFIGRLDIVDNTKYLYFTSNQFQRLPILYQPPDPLGEDRRRRPFVLFRIPLLNSTTTGH", "md5" : "37fcf947f1efc26dbc594ce62a42b74b", "matches" : [ { "signature" : { "accession" : "G3DSA:2.120.10.30", "name" : "TolB", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011042", "name" : "6-blade_b-propeller_TolB-like", "description" : "Six-bladed beta-propeller, TolB-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 29, "end" : 418, "hmmStart" : 7, "hmmEnd" : 337, "hmmLength" : 343, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-77, "score" : 263.1, "envelopeStart" : 29, "envelopeEnd" : 418, "postProcessed" : true, "location-fragments" : [ { "start" : 29, "end" : 418, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.0E-78, "score" : 263.4, "model-ac" : "2qe8A00" }, { "signature" : { "accession" : "SSF63829", "name" : "Calcium-dependent phosphotriesterase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 382, "hmmLength" : 319, "location-fragments" : [ { "start" : 14, "end" : 94, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 121, "end" : 227, "dc-status" : "NC_TERMINAL_DISC" }, { "start" : 263, "end" : 382, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 3.99E-14, "model-ac" : "0052427" }, { "signature" : { "accession" : "PF03022", "name" : "MRJP", "description" : "Major royal jelly protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR017996", "name" : "Royal_jelly/protein_yellow", "description" : "Major royal jelly protein/protein yellow", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 123, "end" : 384, "hmmStart" : 2, "hmmEnd" : 259, "hmmLength" : 287, "hmmBounds" : "INCOMPLETE", "evalue" : 4.7E-28, "score" : 98.4, "envelopeStart" : 122, "envelopeEnd" : 389, "postProcessed" : true, "location-fragments" : [ { "start" : 123, "end" : 384, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-28, "score" : 98.8, "model-ac" : "PF03022" }, { "signature" : { "accession" : "PTHR10009", "name" : "PROTEIN YELLOW-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR017996", "name" : "Royal_jelly/protein_yellow", "description" : "Major royal jelly protein/protein yellow", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 35, "end" : 410, "hmmStart" : 63, "hmmEnd" : 471, "hmmLength" : 502, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 416, "location-fragments" : [ { "start" : 35, "end" : 410, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-44, "familyName" : "", "score" : 154.0, "model-ac" : "PTHR10009" }, { "signature" : { "accession" : "PTHR10009:SF18", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 410, "hmmStart" : 63, "hmmEnd" : 471, "hmmLength" : 502, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 416, "location-fragments" : [ { "start" : 35, "end" : 410, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-44, "familyName" : "", "score" : 154.0, "model-ac" : "PTHR10009:SF18" } ], "xref" : [ { "name" : "XP_018910475.1 PREDICTED: uncharacterized protein LOC109039450 [Bemisia tabaci]", "id" : "XP_018910475.1" } ] },{ "sequence" : "MNSTAKFVTSQVRGQGGVGYGIKGREVFFLNLEDGFFGCQVNESTQVLQLFELSKLCDGKRDCFRGTDELAKELKCTKNCDQVNGHLCQNGACLDSQCHCNDGFGGCDCQVPDENECKYRPCDVFAHCTNTLGSFHCSCFPGYTGNGFYCQDIDECANPAIASRCVANAECCNLPAHFLCKCRPGFEGDGEVECRDIDECLQPNACGINTVCTNTPGNYTCDCQTGYQGNPYNGCVDLNECEYKGACGLGALCTNLPGGHHCECPRGYEGDAYRGVCTDINECLHNVCGINAICRNEPGTFQCSCPQGFAGDPFSSCTDVDECMATPCGVKSECVNTNGSFSCKCLPGYSGEPEKKCLDINECDNPNQCGINAKCMNTPGSYVCVCPEGFSGHGQIYCENVNECSANPCGENAVCTDTVGSFVCSCRQDYTGDPYRKCVDIDECAILDKPCGQNAVCENTDPGFTCTCPQGFAGKPDPSVACEQVDVSVLCAVNSDCAEHAECIEGQCFCLNGFKAQGSLCHDIDECLSLPCGPFSVCNNTQGSFQCSCIPGNVGAPPKIPCKPPCDDIKCGEHAFCKNNEQDAYCICEEGWTFSPADVSAGCIDINECDQVHGVNGQCGLNSICTNSLGGFNCECQQGYSGNPFKQCFDIDECQQNPCGEGALCENTVGSFECSCPPDWLPDPDPSTKCVPILTCKVDKDCPGNAICYDKKFCHCPEPNIGSDCVNPCDAVSCGTNAECVISNNEPSCVCSPGFTGTTPDGCVDIDECDNNPCPIGAVCHNEPGSFSCKCPGGTVGDPFKQGCSQAKIQIGCGPENPCPGSELCIRDDFLEESVCICQRGYLRDAKTGKCRDVNECTELRDKPVCGVNAICKNLPGSYDCQCPPGSNGNPFNSCEECNSSECQCKHPYQLLNGECVLAGCDNGQCPNGAECITIAGQVSYCACPKGFRRQEDGVCEDIDECAEIAQACGYGAECINKRGGYECLCNQGTSGDPYILCSPAQIKCFNHHDCQANEKCIQPGECVCPPPFITDRMDGNKCKSPCEMLSCGINAECNPHDPPRCVCRPGFTGDPLLGCIDIDECVNSPCVAGAKCINEHGSYRCDCPKGVTGEGCADRCSRNPCGENTRCRDVNNGYECSCLPGCSGDPLKGCNCETNRLDACSGHVCGKNALCRMTSGSEPECYCPLEFPVGDPDSECFAKRIPVDCRVSGCGKGAHCVLVGSDYSCQCPPGTVGNPNKDCIPEKECSSNSDCQSDKTCSNHQCLDVCSVKGACGLNALCEPVNHRPKCSCPTCYIGTPKTGCYLDSNCSSLSSQKCSLNSDCPSNLTCIDGFCKNPCLYIDNKNILNCTNHKKCHVQNHKPVCICETGYAVNEYGDLICSPNKVECLNNDDCPSNLACYKSKCSDPCEHTLCSANKTCSVLAHQPVCMCTKDCQPSTLSICMRDSGCPPDLACRNYLCINPCANFSCPARSPCNVEDHKPVCKFCPVGFSADSKFGCVRAVGCVDNEECALNMACINNQCQNPCHMNNPCTNQHDCQVQNHQPVCVKVCSCHKNSNCGPNHYCDGCHCVIDPASRTQSPLPGCEHCPPGVRCDPFTGACMKMNGTAKYPHPCQSDSDCLEIEACYDGQCGDLCALAGTCAPSAECQVYKHRPVCKCPPGYEGDPAVKCFLPEPLSCVTNADCSFMEACINKICQHPCDVHNPCAQNAICSNTNHGASCGCIEGYEGNAYVGCTEVAAKSQRSCQYNGDCPSDKVCDRLNRICVNPCFEDSCGLNAVCIPVNHGTDCRCLAGFHGNPYLGCTSIVQCHNDNECNADEACINGKCSNPCRCGPNAICEVYFHKANCKCLTGYSGNPTIGCIAPTNPCNPNPCGYQALCEVDEGNPICFCPKGMTGNPFKTCIPEGDECSPNPCGPYSGCRVVHGAAVCYCLPEYEGDPPSKPCHLPKNPCSPSPCGPNTQCSLLSDGFAKCTCLPGYVESPNTIRGCVEKRNRCEPNPCGHGAICDPNQAQSCFCPEPLIGNPYRSCTAPSKTLCLPGPCGQNADCYVVGGTEQCYCKMTFTGDPYTSCRPGRSSPCDPNPCGPFAECSISPEGKQHCACLSGMAGDPMSGCSGPECRSNKDCSPTQACLGWKCLDPCPGACGIGASCRVEKHHPQCVCDSGLTGNPLIKCVPVTVLTAPSTNPCEPNPCGLNTLCSVVKNKAACSCLPDFIGDPQSGCRLECVLNSDCPSNQACISHHCKDPCSLGNVCGVGAVCISKDHVVTCVCQKGYSGDPFIQCISKSYLPILKNETLPCDPSPCEPNSYCSVHSGQVAMCNPCGSSGGYWSPACHPDCLFDSDCSFNLACIGQKCMDPCSGSCGFGAQCTVHHHQPICTCPQGLVGNPFEHCHPPTASENQKQDPCAALQCGANAVCKVSFGHTTCVCSPGYQGNPYLGCRPECVLNSDCPSALCCVNNKCEDPCIGACGVNAECQAVNHLPVCYCPKDHSGDPFVSCYAFKPIFAPVMGHPSNPCDPSPCGPNSRCLISKQGYASCSCLPGYRGVPPVCKSECVISAECPQSQACINQKCADPCPGTCGLNARCDTINHNPICNCAPGYVGDPFINCYLPPAEEIPKIPKIDGNPCDPSPCGSNSICQVTQGHPVCSCAMNYTGKPPFCRPECVMSQECPHDQACIREKCRDPCTQSCGYNAKCSVINHTPFCSCLPGYEGDAFVGCSSVPPTVQAPIPTNPCTPSPCGENAHCTSVDGTARCTCIPPYVGNPYAGGCRPECVIPSDCAPHETCLSSHCRDPCPGVCGRNAVCKVVNHIPQCSCLPGFIGNPFQSCKPEPPKPLPPKNPCESAMCGPNSICRVSDGHAVCSCQRDFVGTPPACRPECVQSGECDQTKACVNQKCVDPCPGTCGVQAVCQVLNHNPMCSCPPSTTGDPFVKCVEEAPKEAVESINPCVPSPCGANSECHITERGAMCSCVPGMLGAPPHCRPECSIHADCPTKLACINNKCRDPCMKACGVNSQCAVVNHKPVCSCFDGYQGDPFTRCNPVRASERTPAQTDPCFPTPCGVNADCVNNKGVASCVCLSGFYGNPHSGCHRECESNTDCASSLVCSNYKCVDPCPETCGVEAVCTVSEHKPVCSCAQGFSGDPFIQCHPIPVSPSTPPPVLNPCYPSPCGANSQCRPVNGEAICSCLPQFVGNPPKCHPECTENSDCPADRACVNLKCANPCQNTCGIRAQCTVRNHNPICTCPAKYTGDPFIQCSAIPSSFIQVPSKSSASCQPSPCGPHSQCQIVDNKPVCSCIPGFIGSPPKCRPECVISTDCSSHLTCVKQKCTDPCPGSCGVNAQCQVLNHVPTCSCMEGFTGDSFVHCSPIPMTGVNLETTGDPCLSSPCGINAVCQKGFCFCIGDYEGNPYEECRPECTINHECDRSKACIANKCQDPCPGTCGQFSQCSVVNHMPICSCPQGMTGDPFFSCRMLTAEPSKPKDVCIPSPCGPNSKCQTIEGNAACSCLPGYVGTPPNCKLECVVSSECPSQEACINSKCIDPCTGACGVGARCGVVNHSPICSCGPELTGDPFKSCQDLSMLPSTPPEEDKSVCNPSLCGPNSHCEVEGEIPVCSCLPNFKGRPPHCRPECIINPDCPSNLACINQKCVNPCPGSCGINAECQVISHSVHCSCSPGLTGNPFVQCIQQEKLTNPCTPSPCGPNAYCRQQKNAGSCICIPDYHGNPYEGCRPECVLDSDCSSNFACILNKCTDPCPSTCGQRAVCSVINHVPSCNCLPGHIGDPFVDCNPQPVADTEAALVDPCTPSPCGPNSQCRKANNQPVCSCLPEYKGAPPNCQPECVSNNECPLNKACQNYKCRNPCSGACGLQASCEVISHSPVCSCPAGLMGDPFVRCMLPLAIPSSPIDESDNPCLPSPCGPNSVCRIIKKQAACSCLHGFIGTAPNCRPECTVSSDCSASEACIVGKCRDPCIGSCSNNAECRVQNHAPVCSCVEGYSGDPFSQCSPIMVIEEPSGRDPCTPSPCGANADCFDGNCKCRPSYYGDPYSGCRPECTLNSECPSNKACTNQRCVNPCLGICGQDARCDVINHAPSCSCPPGLTGNPLAACRSFTVQNDTLAGDLCNPNPCGPNSICRITNGFAVCSCQPGLIGSPPLCRPECIVSTECPLTQACIRSKCADPCTGTCGVNAECRVINHSPICSCEPGHTGDPFRQCYAEPMSPGPLPSTENPCKPSPCGPNSKCQVSEGNPVCSCSEHYMGSPPHCRPVCTIDPECPSHLACIGQKCADPCPGSCGSNARCSVINHSPMCACLSGYSGDPFTGCSATEVSLSNEITEADPCYPSPCGSNARCQNDDGFVICECIAEYQGNPYEGCRPECLVSSDCPMNLACIGNKCHDPCPGTCGFSAICTVSNHNPICTCPEGTTGDAFKLCQLIQKSDSTVTLSSPCSRSPCGPNAVCRVINNAAMCECLPDFYGSPSDSGCRPECVISADCPRNKACSGNKCQDPCPGICGTNAICHVVNHSPVCSCPVSMVGDPFIECRLAPAESTDPCFPSPCHKNGICNIIGGSTTCIYPECIINQDCPRDKACFSQKCSDPCYDACGVNAICHAVNHQPVCFCPPGFTGEPQVLCKMQPTSAEPRIECTSDTECNNDRACVSGSCKNPCATSSNVCGINAECHVQFHRPICACKSGFIGNALVQCQEAGCQDNSGCSTMEACINGECVNPCTFSQCGVNAECHPDNNHRARCSCPASFTGDPLVKCERPQCSSNDDCPQNLACQNKRCVNPCICANNALCIVISHNPTCQCPPGFVGNPYRSCVIAPIEVSPGCKQDSDCPSRHVCMSGDCRDPCIGIQPCGQNAECKVLNTLPLRTLSCQCLPGYVGDASVQCERAAAQVEHGCKGDAECLESEVCINLLCVNPCAVSTPCAPSAECQADNHRAMCKCPPGLVGDPFVNCYKASVKSPECSVDSDCATDVACINQRCQDPCILSNLCGAGAQCSVSMHRPVCDCPADWAGDPQVQCYKPECQSNADCVYDKACVENSCLDPCQETTCGRGAECKVQNHHASCTCPLGTQGDPLISCIGVICQFNDDCADHESCDRVNHKCRPVCQEKTCATNAACSAANHQATCTCMPGTQGNPYTDCSTARLPAPVCSQDADCPSKLACINQRCENPCLASHICTKEQDCRVLDTLPLRSVVCECPSDTIATPEGSCKPIAGTTKDPKCRSSEECKNNEKCFKGVCTDACRVEPCGVNAQCIGKKHQAVCSCPPGYIGSPYFECSSLPKLPLPVLPECTRDNDCSYGLGCNRQRCVNPCTTKVCSRNAFCHVEGHKPICRCPPGFSGDPMVECKPSTEAATIGCSSNAECPLQESCVNRLCISPCNCGPNADCKVLDHYPICSCSPGFSGNPQFGCVKVDCESDSHCLSSQTCYNGKCVNPCILEDACAPNAECYGDNHQTACRCAPGYEGNPLVRCEHVECHSDSECRSDQKCFNLHCVNPCQNSPCAPNAVCYVNNHNAACRCPESLPLGNPAVNCERQPSFGKEPECKYDTDCVSGLACLTNKCVDPCYELVPCSNSARCNVLDSVPVKTLTCTCSEGWVPNAEGECRPVVVPSPPGCATNQDCPSNETCISRICRNPCNCGANANCIVQDHYPICSCQEGFEGNPHIACRSIGCRTDGECESGKACLNSHCIDPCLVSNPCGFDAECYTIGNRAECRCVSGYRGDPYDRCTVIGCRTNNDCPDDRACINSQCINPCAYEHPCAANSECKVNNHLALCRCPPGELGNPYVGCRPEPKPECKVDADCPAKLACFNDVCQNPCTALQPCTSPAECSVVSSLPVRTMLCVCPNGYASSGSGTCKAAPPIIPIGCIADSDCPLHKACVNALCMSPCNCPSYAECQVSDHKPTCSCPPGFEGDPNIECVKIDCPANKGFIRAENGECVCPLGYALNANDECQPCYINQGYKIDENDRCTCALDRGFIVNEFGECVCPTEFGYQRDTNGNCVLVGECEKDDNCPNKKFCNLNTQICEDACQNTRCGVNAFCNATNHKAVCLCIAGYNGDPYSVCNHTHTVFRTDFPRPDMVVSCLSDGVQVEIHITETGFNGVLYVKGHSKDESCRRIVSVPQEYANQRTEIFKVHFGSCGLLYKNGLADFVLVIQKHPKLVTYKAQAYHIKCVYSTGEQNVTLGFNVSMLTTAGTIANTGPPPTCTMKIVTHTGQEINSAEIGDNLMLQVDVQPSSIYGGFARSCIAKTMEDSVENEYIVTDENGCATDPSIFGDWDYNPDTQSLLATFNAFKFPSSDNIRFQCNIRVCFGKCQPSDCRGYNAYGKRRRRDLRYVSKNSSTDVSEALLAGQLREEITIQSNAILTLERSEERVAGPPDAPEPQRAEDICISVIGFIIALIVTALLALVAVAVAVSCWLLAYRRRPTLAGPLPHPPEFPNPLFTTPEPVAEPSPDYHS", "md5" : "e1a75666dceae21858c68337a0cb84f1", "matches" : [ { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4605, "end" : 4619, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CfCppGFtgepqvlC", "location-fragments" : [ { "start" : 4605, "end" : 4619, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "SM00286", "name" : "PTI_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 3185, "end" : 3212, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 43.0, "score" : 9.1, "location-fragments" : [ { "start" : 3185, "end" : 3212, "dc-status" : "CONTINUOUS" } ] }, { "start" : 688, "end" : 715, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 11.0, "score" : 12.5, "location-fragments" : [ { "start" : 688, "end" : 715, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5275, "end" : 5302, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 750.0, "score" : 1.8, "location-fragments" : [ { "start" : 5275, "end" : 5302, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4625, "end" : 4650, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 100.0, "score" : 6.8, "location-fragments" : [ { "start" : 4625, "end" : 4650, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1306, "end" : 1334, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 99.0, "score" : 6.9, "location-fragments" : [ { "start" : 1306, "end" : 1334, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4808, "end" : 4836, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 23.0, "score" : 10.6, "location-fragments" : [ { "start" : 4808, "end" : 4836, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4880, "end" : 4907, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 230.0, "score" : 4.8, "location-fragments" : [ { "start" : 4880, "end" : 4907, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1377, "end" : 1404, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 320.0, "score" : 3.9, "location-fragments" : [ { "start" : 1377, "end" : 1404, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4943, "end" : 4973, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 1200.0, "score" : 0.6, "location-fragments" : [ { "start" : 4943, "end" : 4973, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5851, "end" : 5878, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 95.0, "score" : 7.0, "location-fragments" : [ { "start" : 5851, "end" : 5878, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3931, "end" : 3958, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 160.0, "score" : 5.8, "location-fragments" : [ { "start" : 3931, "end" : 3958, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1798, "end" : 1824, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 88.0, "score" : 7.2, "location-fragments" : [ { "start" : 1798, "end" : 1824, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1603, "end" : 1630, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 13.0, "score" : 12.0, "location-fragments" : [ { "start" : 1603, "end" : 1630, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5780, "end" : 5807, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 190.0, "score" : 5.2, "location-fragments" : [ { "start" : 5780, "end" : 5807, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5401, "end" : 5425, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 900.0, "score" : 1.3, "location-fragments" : [ { "start" : 5401, "end" : 5425, "dc-status" : "CONTINUOUS" } ] }, { "start" : 996, "end" : 1024, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 230.0, "score" : 4.7, "location-fragments" : [ { "start" : 996, "end" : 1024, "dc-status" : "CONTINUOUS" } ] }, { "start" : 480, "end" : 509, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 1200.0, "score" : 0.5, "location-fragments" : [ { "start" : 480, "end" : 509, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3044, "end" : 3076, "hmmStart" : 1, "hmmEnd" : 29, "hmmLength" : 29, "hmmBounds" : "COMPLETE", "evalue" : 320.0, "score" : 4.0, "location-fragments" : [ { "start" : 3044, "end" : 3076, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-27, "score" : 104.8, "model-ac" : "SM00286" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 765, "end" : 798, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 782, "end" : 782, "residue" : "N" }, { "start" : 768, "end" : 768, "residue" : "E" }, { "start" : 765, "end" : 765, "residue" : "D" } ] } ], "evalue" : 7.39675E-4, "score" : 38.3866, "location-fragments" : [ { "start" : 765, "end" : 798, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 137, "end" : 150, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M6I1M", "alignment" : "CsCfpGYtgngfyC", "location-fragments" : [ { "start" : 137, "end" : 150, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4856, "end" : 5921, "hmmStart" : 2759, "hmmEnd" : 3810, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4855, "envelopeEnd" : 5934, "location-fragments" : [ { "start" : 4856, "end" : 5921, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 400, "end" : 433, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 400, "end" : 400, "residue" : "N" }, { "start" : 417, "end" : 417, "residue" : "D" }, { "start" : 403, "end" : 403, "residue" : "E" } ] } ], "evalue" : 0.00137515, "score" : 37.6162, "location-fragments" : [ { "start" : 400, "end" : 433, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 69, "end" : 231, "hmmStart" : 33, "hmmEnd" : 190, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 40, "envelopeEnd" : 234, "location-fragments" : [ { "start" : 69, "end" : 231, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3531, "end" : 3568, "score" : 7.183, "alignment" : "-IDPCTGACGVGARCGVVNH--SPICSCGPELTGdpfKSCQ", "location-fragments" : [ { "start" : 3531, "end" : 3568, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2566, "end" : 2603, "score" : 7.204, "alignment" : "-ADPCPGTCGLNARCDTINH--NPICNCAPGYVGdpfINCY", "location-fragments" : [ { "start" : 2566, "end" : 2603, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SSF90148", "name" : "DPY module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 3721, "end" : 3744, "hmmLength" : 24, "location-fragments" : [ { "start" : 3721, "end" : 3744, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.45E-5, "model-ac" : "0048576" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2785, "end" : 2819, "score" : 7.656, "alignment" : "-RDPCPGVCGRNAVCKVVNH--IPQCSCLPGFIGNPFQ", "location-fragments" : [ { "start" : 2785, "end" : 2819, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SM00274", "name" : "FOLN_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003645", "name" : "Fol_N", "description" : "Follistatin-like, N-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 920, "end" : 943, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 89.0, "score" : 2.5, "location-fragments" : [ { "start" : 920, "end" : 943, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5036, "end" : 5058, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 0.02, "score" : 24.1, "location-fragments" : [ { "start" : 5036, "end" : 5058, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4909, "end" : 4932, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 170.0, "score" : 0.0, "location-fragments" : [ { "start" : 4909, "end" : 4932, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1406, "end" : 1428, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 7.6, "score" : 11.5, "location-fragments" : [ { "start" : 1406, "end" : 1428, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1461, "end" : 1483, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 28.0, "score" : 6.7, "location-fragments" : [ { "start" : 1461, "end" : 1483, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2509, "end" : 2532, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 20.0, "score" : 7.9, "location-fragments" : [ { "start" : 2509, "end" : 2532, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4714, "end" : 4737, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 53.0, "score" : 4.4, "location-fragments" : [ { "start" : 4714, "end" : 4737, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4386, "end" : 4407, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 88.0, "score" : 2.5, "location-fragments" : [ { "start" : 4386, "end" : 4407, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3685, "end" : 3707, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 57.0, "score" : 4.2, "location-fragments" : [ { "start" : 3685, "end" : 3707, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4219, "end" : 4241, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 65.0, "score" : 3.7, "location-fragments" : [ { "start" : 4219, "end" : 4241, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3214, "end" : 3235, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 150.0, "score" : 0.5, "location-fragments" : [ { "start" : 3214, "end" : 3235, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3156, "end" : 3178, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 160.0, "score" : 0.4, "location-fragments" : [ { "start" : 3156, "end" : 3178, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1864, "end" : 1886, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 37.0, "score" : 5.8, "location-fragments" : [ { "start" : 1864, "end" : 1886, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2834, "end" : 2856, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 61.0, "score" : 3.9, "location-fragments" : [ { "start" : 2834, "end" : 2856, "dc-status" : "CONTINUOUS" } ] }, { "start" : 728, "end" : 750, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 1.4, "score" : 17.7, "location-fragments" : [ { "start" : 728, "end" : 750, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2399, "end" : 2421, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 29.0, "score" : 6.7, "location-fragments" : [ { "start" : 2399, "end" : 2421, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2352, "end" : 2373, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 11.0, "score" : 10.1, "location-fragments" : [ { "start" : 2352, "end" : 2373, "dc-status" : "CONTINUOUS" } ] }, { "start" : 565, "end" : 587, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 44.0, "score" : 5.1, "location-fragments" : [ { "start" : 565, "end" : 587, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1160, "end" : 1183, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 16.0, "score" : 8.8, "location-fragments" : [ { "start" : 1160, "end" : 1183, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5488, "end" : 5510, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 64.0, "score" : 3.7, "location-fragments" : [ { "start" : 5488, "end" : 5510, "dc-status" : "CONTINUOUS" } ] }, { "start" : 768, "end" : 790, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 110.0, "score" : 1.6, "location-fragments" : [ { "start" : 768, "end" : 790, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5304, "end" : 5326, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 120.0, "score" : 1.3, "location-fragments" : [ { "start" : 5304, "end" : 5326, "dc-status" : "CONTINUOUS" } ] }, { "start" : 6022, "end" : 6044, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 31.0, "score" : 6.4, "location-fragments" : [ { "start" : 6022, "end" : 6044, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4435, "end" : 4457, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 15.0, "score" : 8.9, "location-fragments" : [ { "start" : 4435, "end" : 4457, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5462, "end" : 5486, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 35.0, "score" : 6.0, "location-fragments" : [ { "start" : 5462, "end" : 5486, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1257, "end" : 1280, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 140.0, "score" : 0.8, "location-fragments" : [ { "start" : 1257, "end" : 1280, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2135, "end" : 2156, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 53.0, "score" : 4.4, "location-fragments" : [ { "start" : 2135, "end" : 2156, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5098, "end" : 5120, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 69.0, "score" : 3.5, "location-fragments" : [ { "start" : 5098, "end" : 5120, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-44, "score" : 162.8, "model-ac" : "SM00274" }, { "signature" : { "accession" : "PS01187", "name" : "EGF_CA", "description" : "Calcium-binding EGF-like domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018097", "name" : "EGF_Ca-bd_CS", "description" : "EGF-like calcium-binding, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1078, "end" : 1102, "level" : "STRONG", "cigarAlignment" : "1M1I3M4I1M5I1M1I1M4I1M1I1M", "alignment" : "DiDECvnspCvagakCiNehgsYrC", "location-fragments" : [ { "start" : 1078, "end" : 1102, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01187" }, { "signature" : { "accession" : "SSF90148", "name" : "DPY module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 3300, "end" : 3323, "hmmLength" : 24, "location-fragments" : [ { "start" : 3300, "end" : 3323, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.58E-5, "model-ac" : "0048576" }, { "signature" : { "accession" : "PS01187", "name" : "EGF_CA", "description" : "Calcium-binding EGF-like domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018097", "name" : "EGF_Ca-bd_CS", "description" : "EGF-like calcium-binding, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 152, "end" : 180, "level" : "STRONG", "cigarAlignment" : "1M1I3M8I1M5I1M1I1M4I1M1I1M", "alignment" : "DiDECanpaiasrCvanaeCcNlpahFlC", "location-fragments" : [ { "start" : 152, "end" : 180, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01187" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5233, "end" : 5269, "score" : 9.482, "alignment" : "-TDACRvEPCGVNAQCIGKKH--QAVCSCPPGYIGsPYFE", "location-fragments" : [ { "start" : 5233, "end" : 5269, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1555, "end" : 1766, "hmmStart" : 2805, "hmmEnd" : 3004, "hmmLength" : 4330, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 1548, "envelopeEnd" : 1766, "location-fragments" : [ { "start" : 1555, "end" : 1766, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1739, "end" : 1859, "hmmStart" : 3491, "hmmEnd" : 3609, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1734, "envelopeEnd" : 1862, "location-fragments" : [ { "start" : 1739, "end" : 1859, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3683, "end" : 4408, "hmmStart" : 1248, "hmmEnd" : 2003, "hmmLength" : 4330, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 3681, "envelopeEnd" : 4408, "location-fragments" : [ { "start" : 3683, "end" : 4408, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "SSF90148", "name" : "DPY module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 2975, "end" : 2998, "hmmLength" : 24, "location-fragments" : [ { "start" : 2975, "end" : 2998, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.11E-5, "model-ac" : "0048576" }, { "signature" : { "accession" : "SM00181", "name" : "egf_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 608, "end" : 649, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 3.7, "score" : 16.5, "location-fragments" : [ { "start" : 608, "end" : 649, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5623, "end" : 5660, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 22.0, "score" : 12.0, "location-fragments" : [ { "start" : 5623, "end" : 5660, "dc-status" : "CONTINUOUS" } ] }, { "start" : 768, "end" : 805, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.02, "score" : 24.1, "location-fragments" : [ { "start" : 768, "end" : 805, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5304, "end" : 5340, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.002, "score" : 27.4, "location-fragments" : [ { "start" : 5304, "end" : 5340, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1160, "end" : 1198, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 100.0, "score" : 4.6, "location-fragments" : [ { "start" : 1160, "end" : 1198, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5235, "end" : 5271, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.01, "score" : 25.0, "location-fragments" : [ { "start" : 5235, "end" : 5271, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1457, "end" : 1498, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 79.0, "score" : 5.7, "location-fragments" : [ { "start" : 1457, "end" : 1498, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1081, "end" : 1114, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 7.6E-4, "score" : 28.8, "location-fragments" : [ { "start" : 1081, "end" : 1114, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3851, "end" : 3886, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 1.4, "score" : 18.0, "location-fragments" : [ { "start" : 3851, "end" : 3886, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4063, "end" : 4098, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.38, "score" : 19.8, "location-fragments" : [ { "start" : 4063, "end" : 4098, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2834, "end" : 2869, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 3.7, "score" : 16.5, "location-fragments" : [ { "start" : 2834, "end" : 2869, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2620, "end" : 2655, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.3, "score" : 20.2, "location-fragments" : [ { "start" : 2620, "end" : 2655, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4495, "end" : 4530, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 9.7, "score" : 15.1, "location-fragments" : [ { "start" : 4495, "end" : 4530, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3428, "end" : 3463, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 10.0, "score" : 15.1, "location-fragments" : [ { "start" : 3428, "end" : 3463, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3584, "end" : 3619, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 30.0, "score" : 10.6, "location-fragments" : [ { "start" : 3584, "end" : 3619, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1696, "end" : 1733, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.12, "score" : 21.5, "location-fragments" : [ { "start" : 1696, "end" : 1733, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2458, "end" : 2493, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 54.0, "score" : 7.6, "location-fragments" : [ { "start" : 2458, "end" : 2493, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3047, "end" : 3087, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 8.1, "score" : 15.4, "location-fragments" : [ { "start" : 3047, "end" : 3087, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5876, "end" : 5913, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 2.4, "score" : 17.2, "location-fragments" : [ { "start" : 5876, "end" : 5913, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3685, "end" : 3721, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 18.0, "score" : 13.2, "location-fragments" : [ { "start" : 3685, "end" : 3721, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4386, "end" : 4421, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 3.0, "score" : 16.8, "location-fragments" : [ { "start" : 4386, "end" : 4421, "dc-status" : "CONTINUOUS" } ] }, { "start" : 728, "end" : 764, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.11, "score" : 21.7, "location-fragments" : [ { "start" : 728, "end" : 764, "dc-status" : "CONTINUOUS" } ] }, { "start" : 443, "end" : 483, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-6, "score" : 37.9, "location-fragments" : [ { "start" : 443, "end" : 483, "dc-status" : "CONTINUOUS" } ] }, { "start" : 282, "end" : 318, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-4, "score" : 30.1, "location-fragments" : [ { "start" : 282, "end" : 318, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4838, "end" : 4879, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.018, "score" : 24.2, "location-fragments" : [ { "start" : 4838, "end" : 4879, "dc-status" : "CONTINUOUS" } ] }, { "start" : 116, "end" : 151, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 5.9E-4, "score" : 29.1, "location-fragments" : [ { "start" : 116, "end" : 151, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4219, "end" : 4254, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 1.1, "score" : 18.3, "location-fragments" : [ { "start" : 4219, "end" : 4254, "dc-status" : "CONTINUOUS" } ] }, { "start" : 812, "end" : 852, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 89.0, "score" : 5.1, "location-fragments" : [ { "start" : 812, "end" : 852, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4008, "end" : 4040, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 38.0, "score" : 9.4, "location-fragments" : [ { "start" : 4008, "end" : 4040, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3156, "end" : 3191, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 13.0, "score" : 14.7, "location-fragments" : [ { "start" : 3156, "end" : 3191, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4771, "end" : 4808, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.0012, "score" : 28.1, "location-fragments" : [ { "start" : 4771, "end" : 4808, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2892, "end" : 2927, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 24.0, "score" : 11.7, "location-fragments" : [ { "start" : 2892, "end" : 2927, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4435, "end" : 4472, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.063, "score" : 22.4, "location-fragments" : [ { "start" : 4435, "end" : 4472, "dc-status" : "CONTINUOUS" } ] }, { "start" : 6022, "end" : 6058, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 25.0, "score" : 11.4, "location-fragments" : [ { "start" : 6022, "end" : 6058, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3214, "end" : 3249, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 2.6, "score" : 17.1, "location-fragments" : [ { "start" : 3214, "end" : 3249, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1004, "end" : 1040, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 28.0, "score" : 10.8, "location-fragments" : [ { "start" : 1004, "end" : 1040, "dc-status" : "CONTINUOUS" } ] }, { "start" : 961, "end" : 999, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.035, "score" : 23.3, "location-fragments" : [ { "start" : 961, "end" : 999, "dc-status" : "CONTINUOUS" } ] }, { "start" : 526, "end" : 563, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 21.0, "score" : 12.3, "location-fragments" : [ { "start" : 526, "end" : 563, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4111, "end" : 4146, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 3.5, "score" : 16.6, "location-fragments" : [ { "start" : 4111, "end" : 4146, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4327, "end" : 4363, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 28.0, "score" : 10.9, "location-fragments" : [ { "start" : 4327, "end" : 4363, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1947, "end" : 1986, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 4.3, "score" : 16.3, "location-fragments" : [ { "start" : 1947, "end" : 1986, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4909, "end" : 4946, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.084, "score" : 22.0, "location-fragments" : [ { "start" : 4909, "end" : 4946, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1116, "end" : 1154, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 14.0, "score" : 14.2, "location-fragments" : [ { "start" : 1116, "end" : 1154, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2135, "end" : 2170, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 13.0, "score" : 14.7, "location-fragments" : [ { "start" : 2135, "end" : 2170, "dc-status" : "CONTINUOUS" } ] }, { "start" : 240, "end" : 278, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.058, "score" : 22.5, "location-fragments" : [ { "start" : 240, "end" : 278, "dc-status" : "CONTINUOUS" } ] }, { "start" : 79, "end" : 110, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 23.0, "score" : 11.9, "location-fragments" : [ { "start" : 79, "end" : 110, "dc-status" : "CONTINUOUS" } ] }, { "start" : 155, "end" : 195, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 11.0, "score" : 14.9, "location-fragments" : [ { "start" : 155, "end" : 195, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5366, "end" : 5403, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 60.0, "score" : 7.1, "location-fragments" : [ { "start" : 5366, "end" : 5403, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3475, "end" : 3510, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.61, "score" : 19.1, "location-fragments" : [ { "start" : 3475, "end" : 3510, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4652, "end" : 4690, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.018, "score" : 24.2, "location-fragments" : [ { "start" : 4652, "end" : 4690, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2074, "end" : 2111, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 44.0, "score" : 8.7, "location-fragments" : [ { "start" : 2074, "end" : 2111, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5427, "end" : 5464, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.11, "score" : 21.6, "location-fragments" : [ { "start" : 5427, "end" : 5464, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4714, "end" : 4751, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.11, "score" : 21.6, "location-fragments" : [ { "start" : 4714, "end" : 4751, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2568, "end" : 2603, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 2.8, "score" : 16.9, "location-fragments" : [ { "start" : 2568, "end" : 2603, "dc-status" : "CONTINUOUS" } ] }, { "start" : 653, "end" : 691, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 1.0E-4, "score" : 31.7, "location-fragments" : [ { "start" : 653, "end" : 691, "dc-status" : "CONTINUOUS" } ] }, { "start" : 362, "end" : 399, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 8.2E-5, "score" : 32.0, "location-fragments" : [ { "start" : 362, "end" : 399, "dc-status" : "CONTINUOUS" } ] }, { "start" : 490, "end" : 522, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 16.0, "score" : 13.7, "location-fragments" : [ { "start" : 490, "end" : 522, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2509, "end" : 2545, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.62, "score" : 19.1, "location-fragments" : [ { "start" : 2509, "end" : 2545, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2352, "end" : 2387, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 2.1, "score" : 17.3, "location-fragments" : [ { "start" : 2352, "end" : 2387, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5809, "end" : 5850, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 11.0, "score" : 14.9, "location-fragments" : [ { "start" : 5809, "end" : 5850, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2727, "end" : 2764, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 2.1, "score" : 17.3, "location-fragments" : [ { "start" : 2727, "end" : 2764, "dc-status" : "CONTINUOUS" } ] }, { "start" : 920, "end" : 957, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.94, "score" : 18.5, "location-fragments" : [ { "start" : 920, "end" : 957, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3323, "end" : 3358, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.4, "score" : 19.7, "location-fragments" : [ { "start" : 3323, "end" : 3358, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2940, "end" : 2975, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.15, "score" : 21.1, "location-fragments" : [ { "start" : 2940, "end" : 2975, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5684, "end" : 5721, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.073, "score" : 22.2, "location-fragments" : [ { "start" : 5684, "end" : 5721, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4277, "end" : 4312, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 4.8, "score" : 16.1, "location-fragments" : [ { "start" : 4277, "end" : 4312, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1205, "end" : 1241, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.0021, "score" : 27.3, "location-fragments" : [ { "start" : 1205, "end" : 1241, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3744, "end" : 3779, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 19.0, "score" : 12.9, "location-fragments" : [ { "start" : 3744, "end" : 3779, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5488, "end" : 5525, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 5.2, "score" : 16.0, "location-fragments" : [ { "start" : 5488, "end" : 5525, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2678, "end" : 2713, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 1.2, "score" : 18.2, "location-fragments" : [ { "start" : 2678, "end" : 2713, "dc-status" : "CONTINUOUS" } ] }, { "start" : 695, "end" : 726, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 72.0, "score" : 6.2, "location-fragments" : [ { "start" : 695, "end" : 726, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5163, "end" : 5204, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 31.0, "score" : 10.3, "location-fragments" : [ { "start" : 5163, "end" : 5204, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3642, "end" : 3677, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 2.5, "score" : 17.1, "location-fragments" : [ { "start" : 3642, "end" : 3677, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3265, "end" : 3300, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.09, "score" : 21.9, "location-fragments" : [ { "start" : 3265, "end" : 3300, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2182, "end" : 2218, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 4.2, "score" : 16.3, "location-fragments" : [ { "start" : 2182, "end" : 2218, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2998, "end" : 3033, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 12.0, "score" : 14.8, "location-fragments" : [ { "start" : 2998, "end" : 3033, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1905, "end" : 1942, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 37.0, "score" : 9.4, "location-fragments" : [ { "start" : 1905, "end" : 1942, "dc-status" : "CONTINUOUS" } ] }, { "start" : 322, "end" : 358, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.0075, "score" : 25.5, "location-fragments" : [ { "start" : 322, "end" : 358, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2399, "end" : 2435, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.84, "score" : 18.7, "location-fragments" : [ { "start" : 2399, "end" : 2435, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1822, "end" : 1859, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 18.0, "score" : 13.2, "location-fragments" : [ { "start" : 1822, "end" : 1859, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5556, "end" : 5597, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.97, "score" : 18.5, "location-fragments" : [ { "start" : 5556, "end" : 5597, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3793, "end" : 3828, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.042, "score" : 23.0, "location-fragments" : [ { "start" : 3793, "end" : 3828, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4585, "end" : 4620, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.015, "score" : 24.5, "location-fragments" : [ { "start" : 4585, "end" : 4620, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2032, "end" : 2068, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 19.0, "score" : 12.7, "location-fragments" : [ { "start" : 2032, "end" : 2068, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4975, "end" : 5012, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 1.6, "score" : 17.7, "location-fragments" : [ { "start" : 4975, "end" : 5012, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1632, "end" : 1669, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.64, "score" : 19.1, "location-fragments" : [ { "start" : 1632, "end" : 1669, "dc-status" : "CONTINUOUS" } ] }, { "start" : 856, "end" : 896, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.011, "score" : 25.0, "location-fragments" : [ { "start" : 856, "end" : 896, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5098, "end" : 5134, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 25.0, "score" : 11.5, "location-fragments" : [ { "start" : 5098, "end" : 5134, "dc-status" : "CONTINUOUS" } ] }, { "start" : 199, "end" : 236, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.11, "score" : 21.6, "location-fragments" : [ { "start" : 199, "end" : 236, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3373, "end" : 3405, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 70.0, "score" : 6.4, "location-fragments" : [ { "start" : 3373, "end" : 3405, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2241, "end" : 2278, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.0076, "score" : 25.5, "location-fragments" : [ { "start" : 2241, "end" : 2278, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3533, "end" : 3568, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 19.0, "score" : 12.8, "location-fragments" : [ { "start" : 3533, "end" : 3568, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1991, "end" : 2026, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 31.0, "score" : 10.3, "location-fragments" : [ { "start" : 1991, "end" : 2026, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5745, "end" : 5782, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 20.0, "score" : 12.6, "location-fragments" : [ { "start" : 5745, "end" : 5782, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4169, "end" : 4204, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.89, "score" : 18.6, "location-fragments" : [ { "start" : 4169, "end" : 4204, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3091, "end" : 3141, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 26.0, "score" : 11.2, "location-fragments" : [ { "start" : 3091, "end" : 3141, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1765, "end" : 1801, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 13.0, "score" : 14.6, "location-fragments" : [ { "start" : 1765, "end" : 1801, "dc-status" : "CONTINUOUS" } ] }, { "start" : 565, "end" : 604, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.96, "score" : 18.5, "location-fragments" : [ { "start" : 565, "end" : 604, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1406, "end" : 1442, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 220.0, "score" : 0.7, "location-fragments" : [ { "start" : 1406, "end" : 1442, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1864, "end" : 1900, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.054, "score" : 22.6, "location-fragments" : [ { "start" : 1864, "end" : 1900, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3902, "end" : 3937, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.028, "score" : 23.6, "location-fragments" : [ { "start" : 3902, "end" : 3937, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1042, "end" : 1077, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.14, "score" : 21.3, "location-fragments" : [ { "start" : 1042, "end" : 1077, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1336, "end" : 1380, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 15.0, "score" : 14.0, "location-fragments" : [ { "start" : 1336, "end" : 1380, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2787, "end" : 2822, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.28, "score" : 20.3, "location-fragments" : [ { "start" : 2787, "end" : 2822, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5036, "end" : 5072, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.47, "score" : 19.5, "location-fragments" : [ { "start" : 5036, "end" : 5072, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3960, "end" : 3995, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 0.1, "score" : 21.7, "location-fragments" : [ { "start" : 3960, "end" : 3995, "dc-status" : "CONTINUOUS" } ] }, { "start" : 403, "end" : 439, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 32, "hmmBounds" : "COMPLETE", "evalue" : 5.6E-5, "score" : 32.5, "location-fragments" : [ { "start" : 403, "end" : 439, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "score" : 1893.6, "model-ac" : "SM00181" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5486, "end" : 5525, "score" : 8.237, "alignment" : "-VNPCQnSPCAPNAVCYVNNH--NAACRCPEslplGNPAVNCE", "location-fragments" : [ { "start" : 5486, "end" : 5525, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2029, "end" : 2068, "score" : 6.812, "alignment" : "SKTLCLpGPCGQNADCYVVGG--TEQCYCKMTFTGdpyTSCR", "location-fragments" : [ { "start" : 2029, "end" : 2068, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 319, "end" : 351, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 336, "end" : 336, "residue" : "N" }, { "start" : 319, "end" : 319, "residue" : "D" }, { "start" : 322, "end" : 322, "residue" : "E" } ] } ], "evalue" : 0.00347054, "score" : 36.4606, "location-fragments" : [ { "start" : 319, "end" : 351, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2396, "end" : 2435, "score" : 10.735, "alignment" : "KQDPCAaLQCGANAVCKVSFG--HTTCVCSPGYQGnpyLGCR", "location-fragments" : [ { "start" : 2396, "end" : 2435, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 237, "end" : 271, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 237, "end" : 237, "residue" : "D" }, { "start" : 240, "end" : 240, "residue" : "E" }, { "start" : 255, "end" : 255, "residue" : "N" } ] } ], "evalue" : 8.57336E-4, "score" : 38.0014, "location-fragments" : [ { "start" : 237, "end" : 271, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3496, "end" : 3509, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M6I1M", "alignment" : "CsClpGYvgtppnC", "location-fragments" : [ { "start" : 3496, "end" : 3509, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2263, "end" : 2277, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CvCqkGYsgdpfiqC", "location-fragments" : [ { "start" : 2263, "end" : 2277, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3286, "end" : 3299, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M6I1M", "alignment" : "CsCipGFigsppkC", "location-fragments" : [ { "start" : 3286, "end" : 3299, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2617, "end" : 2655, "score" : 14.249, "alignment" : "DGNPCDpSPCGSNSICQVTQG--HPVCSCAMNYTGkpPFCR", "location-fragments" : [ { "start" : 2617, "end" : 2655, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1078, "end" : 1113, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 1081, "end" : 1081, "residue" : "E" }, { "start" : 1078, "end" : 1078, "residue" : "D" }, { "start" : 1095, "end" : 1095, "residue" : "N" } ] } ], "evalue" : 2.31698E-4, "score" : 39.5422, "location-fragments" : [ { "start" : 1078, "end" : 1113, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4650, "end" : 4690, "score" : 8.024, "alignment" : "-KNPCAtssNVCGINAECHVQFH--RPICACKSGFIGnalVQCQ", "location-fragments" : [ { "start" : 4650, "end" : 4690, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4297, "end" : 4311, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CaClsGYsgdpftgC", "location-fragments" : [ { "start" : 4297, "end" : 4311, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2292, "end" : 2831, "hmmStart" : 1476, "hmmEnd" : 2025, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2280, "envelopeEnd" : 2833, "location-fragments" : [ { "start" : 2292, "end" : 2831, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "PS00022", "name" : "EGF_1", "description" : "EGF-like domain signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1102, "end" : 1113, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I1M2I2M1I1M", "alignment" : "CdCpkGvtGEgC", "location-fragments" : [ { "start" : 1102, "end" : 1113, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00022" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4381, "end" : 4805, "hmmStart" : 2316, "hmmEnd" : 2759, "hmmLength" : 4330, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 4381, "envelopeEnd" : 4813, "location-fragments" : [ { "start" : 4381, "end" : 4805, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 853, "end" : 896, "score" : 12.927, "alignment" : "DVNECTelrdkPVCGVNAICKNLPG--SYDCQCPPGSNGnpfNSCE", "location-fragments" : [ { "start" : 853, "end" : 896, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SSF90148", "name" : "DPY module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 3619, "end" : 3642, "hmmLength" : 24, "location-fragments" : [ { "start" : 3619, "end" : 3642, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.62E-6, "model-ac" : "0048576" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1383, "end" : 1440, "hmmStart" : 2187, "hmmEnd" : 2243, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1375, "envelopeEnd" : 1441, "location-fragments" : [ { "start" : 1383, "end" : 1440, "dc-status" : "CONTINUOUS" } ] }, { "start" : 69, "end" : 231, "hmmStart" : 33, "hmmEnd" : 190, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 40, "envelopeEnd" : 234, "location-fragments" : [ { "start" : 69, "end" : 231, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1158, "end" : 1267, "hmmStart" : 862, "hmmEnd" : 970, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1152, "envelopeEnd" : 1268, "location-fragments" : [ { "start" : 1158, "end" : 1267, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3581, "end" : 3619, "score" : 9.702, "alignment" : "DKSVCNpSLCGPNSHCEVEGE--IPVCSCLPNFKGrpPHCR", "location-fragments" : [ { "start" : 3581, "end" : 3619, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3153, "end" : 3191, "score" : 9.664, "alignment" : "VLNPCYpSPCGANSQCRPVNG--EAICSCLPQFVGnpPKCH", "location-fragments" : [ { "start" : 3153, "end" : 3191, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3212, "end" : 3249, "score" : 8.208, "alignment" : "-ANPCQNTCGIRAQCTVRNH--NPICTCPAKYTGdpfIQCS", "location-fragments" : [ { "start" : 3212, "end" : 3249, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SSF90148", "name" : "DPY module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 2869, "end" : 2892, "hmmLength" : 24, "location-fragments" : [ { "start" : 2869, "end" : 2892, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.84E-5, "model-ac" : "0048576" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1157, "end" : 1194, "score" : 8.041, "alignment" : "RLDACSgHVCGKNALCRMTSG-SEPECYCPLEFPVGDPD", "location-fragments" : [ { "start" : 1157, "end" : 1194, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5034, "end" : 5072, "score" : 8.201, "alignment" : "-LDPCQeTTCGRGAECKVQNH--HASCTCPLGTQGdplISCI", "location-fragments" : [ { "start" : 5034, "end" : 5072, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 723, "end" : 805, "hmmStart" : 4, "hmmEnd" : 85, "hmmLength" : 86, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-11, "score" : 46.0, "envelopeStart" : 723, "envelopeEnd" : 805, "postProcessed" : true, "location-fragments" : [ { "start" : 723, "end" : 805, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-137, "score" : 450.4, "model-ac" : "1lmjA00" }, { "signature" : { "accession" : "PS51034", "name" : "ZP_2", "description" : "ZP domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001507", "name" : "ZP_dom", "description" : "Zona pellucida domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6076, "end" : 6319, "score" : 33.365, "alignment" : "SCLSDGVQVEIHITETGFNGVLYVKGHSKDESCRRIVSVPQEyanqrTEIFKVHFGSCGLLY----KNGLADFVLVIQKHPKLVTYKAQAYHIKCVYSTGE-------QNVTLGFNVSMLTTaGTIANTGPPPTCTmKIVTHTGQEINSAEIGDNLMLQVDV--QPSSIYGGFARSCIAKTM-EDSVENEYIVTDENGCATDPSIFGDWDYNPDTQS--LLATFNAFKFPSSDNIRFQCNIRVCFGKCQPSDCRGYNAYG", "location-fragments" : [ { "start" : 6076, "end" : 6319, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51034" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3068, "end" : 3082, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CvClsGFygnphsgC", "location-fragments" : [ { "start" : 3068, "end" : 3082, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 343, "end" : 357, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CkClpGYsgepekkC", "location-fragments" : [ { "start" : 343, "end" : 357, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "G3DSA:2.90.20.10", "name" : "Plasmodium vivax P25 domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1828, "end" : 1947, "hmmStart" : 44, "hmmEnd" : 166, "hmmLength" : 174, "hmmBounds" : "COMPLETE", "evalue" : 7.6E-6, "score" : 27.8, "envelopeStart" : 1828, "envelopeEnd" : 1947, "postProcessed" : true, "location-fragments" : [ { "start" : 1828, "end" : 1947, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-115, "score" : 384.2, "model-ac" : "1z1yA01" }, { "signature" : { "accession" : "SSF90148", "name" : "DPY module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 2330, "end" : 2352, "hmmLength" : 24, "location-fragments" : [ { "start" : 2330, "end" : 2352, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.89E-5, "model-ac" : "0048576" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 319, "end" : 358, "score" : 15.779, "alignment" : "DVDECMaTPCGVKSECVNTNG--SFSCKCLPGYSGepeKKCL", "location-fragments" : [ { "start" : 319, "end" : 358, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 199, "end" : 237, "hmmStart" : 2, "hmmEnd" : 43, "hmmLength" : 45, "hmmBounds" : "INCOMPLETE", "evalue" : 2.3E-10, "score" : 42.3, "envelopeStart" : 195, "envelopeEnd" : 238, "postProcessed" : true, "location-fragments" : [ { "start" : 199, "end" : 237, "dc-status" : "CONTINUOUS" } ] }, { "start" : 362, "end" : 397, "hmmStart" : 2, "hmmEnd" : 42, "hmmLength" : 45, "hmmBounds" : "INCOMPLETE", "evalue" : 1.9E-10, "score" : 42.6, "envelopeStart" : 358, "envelopeEnd" : 400, "postProcessed" : true, "location-fragments" : [ { "start" : 362, "end" : 397, "dc-status" : "CONTINUOUS" } ] }, { "start" : 238, "end" : 279, "hmmStart" : 2, "hmmEnd" : 43, "hmmLength" : 45, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.7E-8, "score" : 35.7, "envelopeStart" : 236, "envelopeEnd" : 279, "postProcessed" : true, "location-fragments" : [ { "start" : 238, "end" : 279, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-82, "score" : 272.4, "model-ac" : "1uzkA01" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5682, "end" : 5721, "score" : 10.692, "alignment" : "-IDPCLvsNPCGFDAECYTIGN--RAECRCVSGYRGdpyDRCT", "location-fragments" : [ { "start" : 5682, "end" : 5721, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3472, "end" : 3510, "score" : 12.788, "alignment" : "PKDVCIpSPCGPNSKCQTIEG--NAACSCLPGYVGtpPNCK", "location-fragments" : [ { "start" : 3472, "end" : 3510, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 625, "end" : 636, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CtNslggFnCeC", "location-fragments" : [ { "start" : 625, "end" : 636, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1944, "end" : 2069, "hmmStart" : 793, "hmmEnd" : 947, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1940, "envelopeEnd" : 2073, "location-fragments" : [ { "start" : 1944, "end" : 2069, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4814, "end" : 4885, "hmmStart" : 3923, "hmmEnd" : 3995, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4806, "envelopeEnd" : 4888, "location-fragments" : [ { "start" : 4814, "end" : 4885, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4324, "end" : 4363, "score" : 9.793, "alignment" : "EADPCYpSPCGSNARCQNDDG--FVICECIAEYQGnpyEGCR", "location-fragments" : [ { "start" : 4324, "end" : 4363, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4836, "end" : 4879, "score" : 9.796, "alignment" : "-RDPCIgiQPCGQNAECKVLNTlpLRTLSCQCLPGYVGdasVQCE", "location-fragments" : [ { "start" : 4836, "end" : 4879, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 443, "end" : 483, "hmmStart" : 2, "hmmEnd" : 37, "hmmLength" : 43, "hmmBounds" : "INCOMPLETE", "evalue" : 8.2E-9, "score" : 37.6, "envelopeStart" : 439, "envelopeEnd" : 485, "postProcessed" : true, "location-fragments" : [ { "start" : 443, "end" : 483, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-77, "score" : 256.7, "model-ac" : "4xl1D01" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2179, "end" : 2218, "score" : 8.445, "alignment" : "STNPCEpNPCGLNTLCSVVKN--KAACSCLPDFIGdpqSGCR", "location-fragments" : [ { "start" : 2179, "end" : 2218, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SSF57196", "name" : "EGF/Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 853, "end" : 891, "hmmLength" : 43, "location-fragments" : [ { "start" : 853, "end" : 891, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.05E-5, "model-ac" : "0044577" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4675, "end" : 4689, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CaCksGFignalvqC", "location-fragments" : [ { "start" : 4675, "end" : 4689, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5743, "end" : 5782, "score" : 6.965, "alignment" : "-INPCAyeHPCAANSECKVNNH--LALCRCPPGELGnpyVGCR", "location-fragments" : [ { "start" : 5743, "end" : 5782, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1079, "end" : 1194, "hmmStart" : 77, "hmmEnd" : 191, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1077, "envelopeEnd" : 1197, "location-fragments" : [ { "start" : 1079, "end" : 1194, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 670, "end" : 1084, "hmmStart" : 340, "hmmEnd" : 780, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 668, "envelopeEnd" : 1085, "location-fragments" : [ { "start" : 670, "end" : 1084, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 440, "end" : 475, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 459, "end" : 459, "residue" : "N" }, { "start" : 440, "end" : 440, "residue" : "D" }, { "start" : 443, "end" : 443, "residue" : "E" } ] } ], "evalue" : 0.00117474, "score" : 37.6162, "location-fragments" : [ { "start" : 440, "end" : 475, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 171, "end" : 182, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CcNlpahFlCkC", "location-fragments" : [ { "start" : 171, "end" : 182, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1786, "end" : 1800, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CrClaGFhgnpylgC", "location-fragments" : [ { "start" : 1786, "end" : 1800, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 780, "end" : 791, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "ChNepgsFsCkC", "location-fragments" : [ { "start" : 780, "end" : 791, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "SM00179", "name" : "egfca_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001881", "name" : "EGF-like_Ca-bd_dom", "description" : "EGF-like calcium-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3474, "end" : 3510, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 0.22, "score" : 7.2, "location-fragments" : [ { "start" : 3474, "end" : 3510, "dc-status" : "CONTINUOUS" } ] }, { "start" : 359, "end" : 399, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-9, "score" : 47.5, "location-fragments" : [ { "start" : 359, "end" : 399, "dc-status" : "CONTINUOUS" } ] }, { "start" : 765, "end" : 805, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 9.1E-9, "score" : 45.1, "location-fragments" : [ { "start" : 765, "end" : 805, "dc-status" : "CONTINUOUS" } ] }, { "start" : 605, "end" : 649, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-7, "score" : 39.3, "location-fragments" : [ { "start" : 605, "end" : 649, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3044, "end" : 3087, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 0.047, "score" : 12.5, "location-fragments" : [ { "start" : 3044, "end" : 3087, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5682, "end" : 5721, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 1.6, "score" : 0.2, "location-fragments" : [ { "start" : 5682, "end" : 5721, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1205, "end" : 1241, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 0.71, "score" : 3.0, "location-fragments" : [ { "start" : 1205, "end" : 1241, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1902, "end" : 1942, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 0.29, "score" : 6.2, "location-fragments" : [ { "start" : 1902, "end" : 1942, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4324, "end" : 4363, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 0.44, "score" : 4.7, "location-fragments" : [ { "start" : 4324, "end" : 4363, "dc-status" : "CONTINUOUS" } ] }, { "start" : 853, "end" : 896, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-7, "score" : 40.9, "location-fragments" : [ { "start" : 853, "end" : 896, "dc-status" : "CONTINUOUS" } ] }, { "start" : 650, "end" : 691, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 9.0E-12, "score" : 55.1, "location-fragments" : [ { "start" : 650, "end" : 691, "dc-status" : "CONTINUOUS" } ] }, { "start" : 237, "end" : 278, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-7, "score" : 40.6, "location-fragments" : [ { "start" : 237, "end" : 278, "dc-status" : "CONTINUOUS" } ] }, { "start" : 196, "end" : 236, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 7.1E-7, "score" : 38.9, "location-fragments" : [ { "start" : 196, "end" : 236, "dc-status" : "CONTINUOUS" } ] }, { "start" : 400, "end" : 439, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 6.2E-10, "score" : 49.0, "location-fragments" : [ { "start" : 400, "end" : 439, "dc-status" : "CONTINUOUS" } ] }, { "start" : 523, "end" : 563, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-6, "score" : 37.6, "location-fragments" : [ { "start" : 523, "end" : 563, "dc-status" : "CONTINUOUS" } ] }, { "start" : 319, "end" : 358, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 4.3E-10, "score" : 49.5, "location-fragments" : [ { "start" : 319, "end" : 358, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1117, "end" : 1152, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 0.83, "score" : 2.4, "location-fragments" : [ { "start" : 1117, "end" : 1152, "dc-status" : "CONTINUOUS" } ] }, { "start" : 566, "end" : 604, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 1.0, "score" : 1.8, "location-fragments" : [ { "start" : 566, "end" : 604, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3791, "end" : 3828, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 0.32, "score" : 5.8, "location-fragments" : [ { "start" : 3791, "end" : 3828, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1078, "end" : 1114, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-9, "score" : 47.0, "location-fragments" : [ { "start" : 1078, "end" : 1114, "dc-status" : "CONTINUOUS" } ] }, { "start" : 152, "end" : 195, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 6.0E-5, "score" : 32.4, "location-fragments" : [ { "start" : 152, "end" : 195, "dc-status" : "CONTINUOUS" } ] }, { "start" : 440, "end" : 483, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 2.0E-10, "score" : 50.6, "location-fragments" : [ { "start" : 440, "end" : 483, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2937, "end" : 2975, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 0.23, "score" : 6.9, "location-fragments" : [ { "start" : 2937, "end" : 2975, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2617, "end" : 2655, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 0.2, "score" : 7.4, "location-fragments" : [ { "start" : 2617, "end" : 2655, "dc-status" : "CONTINUOUS" } ] }, { "start" : 958, "end" : 999, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 7.2E-8, "score" : 42.1, "location-fragments" : [ { "start" : 958, "end" : 999, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2508, "end" : 2545, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 1.4, "score" : 0.6, "location-fragments" : [ { "start" : 2508, "end" : 2545, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2724, "end" : 2768, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 0.69, "score" : 3.1, "location-fragments" : [ { "start" : 2724, "end" : 2768, "dc-status" : "CONTINUOUS" } ] }, { "start" : 279, "end" : 318, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 8.8E-10, "score" : 48.5, "location-fragments" : [ { "start" : 279, "end" : 318, "dc-status" : "CONTINUOUS" } ] }, { "start" : 113, "end" : 151, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 4.0E-8, "score" : 43.0, "location-fragments" : [ { "start" : 113, "end" : 151, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-226, "score" : 768.9, "model-ac" : "SM00179" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3126, "end" : 3140, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CsCaqGFsgdpfiqC", "location-fragments" : [ { "start" : 3126, "end" : 3140, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3104, "end" : 3141, "score" : 7.706, "alignment" : "-VDPCPETCGVEAVCTVSEH--KPVCSCAQGFSGdpfIQCH", "location-fragments" : [ { "start" : 3104, "end" : 3141, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1902, "end" : 1938, "score" : 11.414, "alignment" : "EGDECSpNPCGPYSGCRVVHG--AAVCYCLPEYEGDPPS", "location-fragments" : [ { "start" : 1902, "end" : 1938, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 872, "end" : 883, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CkNlpgsYdCqC", "location-fragments" : [ { "start" : 872, "end" : 883, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1434, "end" : 1572, "hmmStart" : 2850, "hmmEnd" : 2985, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1431, "envelopeEnd" : 1579, "location-fragments" : [ { "start" : 1434, "end" : 1572, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 440, "end" : 483, "score" : 15.824, "alignment" : "DIDECAildKPCGQNAVCENTDP--GFTCTCPQGFAGkpdpsVACE", "location-fragments" : [ { "start" : 440, "end" : 483, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SM00241", "name" : "zp_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001507", "name" : "ZP_dom", "description" : "Zona pellucida domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6076, "end" : 6314, "hmmStart" : 1, "hmmEnd" : 296, "hmmLength" : 296, "hmmBounds" : "COMPLETE", "evalue" : 3.6E-15, "score" : 66.4, "location-fragments" : [ { "start" : 6076, "end" : 6314, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-15, "score" : 66.4, "model-ac" : "SM00241" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2676, "end" : 2710, "score" : 9.585, "alignment" : "-RDPCTQSCGYNAKCSVINH--TPFCSCLPGYEGDAFV", "location-fragments" : [ { "start" : 2676, "end" : 2710, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 359, "end" : 393, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 359, "end" : 359, "residue" : "D" }, { "start" : 362, "end" : 362, "residue" : "E" }, { "start" : 377, "end" : 377, "residue" : "N" } ] } ], "evalue" : 3.07699E-6, "score" : 44.935, "location-fragments" : [ { "start" : 359, "end" : 393, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2420, "end" : 2434, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CvCspGYqgnpylgC", "location-fragments" : [ { "start" : 2420, "end" : 2434, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3640, "end" : 3677, "score" : 7.876, "alignment" : "-VNPCPGSCGINAECQVISH--SVHCSCSPGLTGnpfVQCI", "location-fragments" : [ { "start" : 3640, "end" : 3677, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SSF57196", "name" : "EGF/Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 762, "end" : 804, "hmmLength" : 53, "location-fragments" : [ { "start" : 762, "end" : 804, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-7, "model-ac" : "0045804" }, { "signature" : { "accession" : "PS01187", "name" : "EGF_CA", "description" : "Calcium-binding EGF-like domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018097", "name" : "EGF_Ca-bd_CS", "description" : "EGF-like calcium-binding, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 440, "end" : 466, "level" : "STRONG", "cigarAlignment" : "1M1I3M6I1M5I1M1I1M4I1M1I1M", "alignment" : "DiDECaildkpCgqnavCeNtdpgFtC", "location-fragments" : [ { "start" : 440, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01187" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5302, "end" : 5340, "score" : 9.368, "alignment" : "-VNPCTtKVCSRNAFCHVEGH--KPICRCPPGFSGdpmVECK", "location-fragments" : [ { "start" : 5302, "end" : 5340, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2071, "end" : 2279, "hmmStart" : 793, "hmmEnd" : 1006, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2069, "envelopeEnd" : 2290, "location-fragments" : [ { "start" : 2071, "end" : 2279, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3262, "end" : 3300, "score" : 10.314, "alignment" : "SSASCQpSPCGPHSQCQIVDN--KPVCSCIPGFIGspPKCR", "location-fragments" : [ { "start" : 3262, "end" : 3300, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1630, "end" : 1666, "score" : 8.775, "alignment" : "-GDLCAlaGTCAPSAECQVYKH--RPVCKCPPGYEGDPAV", "location-fragments" : [ { "start" : 1630, "end" : 1666, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 152, "end" : 195, "score" : 10.116, "alignment" : "DIDECAnpaiaSRCVANAECCNLPA--HFLCKCRPGFEGdgeVECR", "location-fragments" : [ { "start" : 152, "end" : 195, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3742, "end" : 3779, "score" : 6.798, "alignment" : "-TDPCPSTCGQRAVCSVINH--VPSCNCLPGHIGdpfVDCN", "location-fragments" : [ { "start" : 3742, "end" : 3779, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4814, "end" : 4885, "hmmStart" : 3923, "hmmEnd" : 3995, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4806, "envelopeEnd" : 4888, "location-fragments" : [ { "start" : 4814, "end" : 4885, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 650, "end" : 687, "score" : 14.913, "alignment" : "DIDECQqNPCGEGALCENTVG--SFECSCPPDWLPdPDPS", "location-fragments" : [ { "start" : 650, "end" : 687, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2071, "end" : 2111, "score" : 9.131, "alignment" : "RSSPCDpNPCGPFAECSISPE-GKQHCACLSGMAGdpmSGCS", "location-fragments" : [ { "start" : 2071, "end" : 2111, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4381, "end" : 4805, "hmmStart" : 2316, "hmmEnd" : 2759, "hmmLength" : 4330, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 4381, "envelopeEnd" : 4813, "location-fragments" : [ { "start" : 4381, "end" : 4805, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3899, "end" : 3937, "score" : 11.249, "alignment" : "SDNPCLpSPCGPNSVCRIIKK--QAACSCLHGFIGtaPNCR", "location-fragments" : [ { "start" : 3899, "end" : 3937, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1555, "end" : 1766, "hmmStart" : 2805, "hmmEnd" : 3004, "hmmLength" : 4330, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 1548, "envelopeEnd" : 1766, "location-fragments" : [ { "start" : 1555, "end" : 1766, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3683, "end" : 4408, "hmmStart" : 1248, "hmmEnd" : 2003, "hmmLength" : 4330, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 3681, "envelopeEnd" : 4408, "location-fragments" : [ { "start" : 3683, "end" : 4408, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4384, "end" : 4421, "score" : 7.957, "alignment" : "-HDPCPGTCGFSAICTVSNH--NPICTCPEGTTGdafKLCQ", "location-fragments" : [ { "start" : 4384, "end" : 4421, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4216, "end" : 4254, "score" : 12.002, "alignment" : "TENPCKpSPCGPNSKCQVSEG--NPVCSCSEHYMGspPHCR", "location-fragments" : [ { "start" : 4216, "end" : 4254, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 398, "end" : 442, "hmmStart" : 7, "hmmEnd" : 60, "hmmLength" : 61, "hmmBounds" : "INCOMPLETE", "evalue" : 3.8E-12, "score" : 48.0, "envelopeStart" : 394, "envelopeEnd" : 445, "postProcessed" : true, "location-fragments" : [ { "start" : 398, "end" : 442, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-99, "score" : 326.7, "model-ac" : "2k2sB00" }, { "signature" : { "accession" : "PS01187", "name" : "EGF_CA", "description" : "Calcium-binding EGF-like domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018097", "name" : "EGF_Ca-bd_CS", "description" : "EGF-like calcium-binding, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 958, "end" : 984, "level" : "STRONG", "cigarAlignment" : "1M1I3M6I1M5I1M1I1M4I1M1I1M", "alignment" : "DiDECaeiaqaCgygaeCiNkrggYeC", "location-fragments" : [ { "start" : 958, "end" : 984, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01187" }, { "signature" : { "accession" : "SSF57184", "name" : "Growth factor receptor domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009030", "name" : "Growth_fac_rcpt_cys_sf", "description" : "Growth factor receptor cysteine-rich domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2553, "end" : 2713, "hmmLength" : 155, "location-fragments" : [ { "start" : 2553, "end" : 2713, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.82E-5, "model-ac" : "0053854" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1093, "end" : 1104, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CiNehgsYrCdC", "location-fragments" : [ { "start" : 1093, "end" : 1104, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 221, "end" : 235, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CdCqtGYqgnpyngC", "location-fragments" : [ { "start" : 221, "end" : 235, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5325, "end" : 5339, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CrCppGFsgdpmveC", "location-fragments" : [ { "start" : 5325, "end" : 5339, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3849, "end" : 3886, "score" : 6.987, "alignment" : "-RNPCSGACGLQASCEVISH--SPVCSCPAGLMGdpfVRCM", "location-fragments" : [ { "start" : 3849, "end" : 3886, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PF07645", "name" : "EGF_CA", "description" : "Calcium-binding EGF domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001881", "name" : "EGF-like_Ca-bd_dom", "description" : "EGF-like calcium-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 113, "end" : 146, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 42, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.7E-4, "score" : 21.0, "envelopeStart" : 113, "envelopeEnd" : 150, "postProcessed" : true, "location-fragments" : [ { "start" : 113, "end" : 146, "dc-status" : "CONTINUOUS" } ] }, { "start" : 523, "end" : 552, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 42, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 8.2E-6, "score" : 25.9, "envelopeStart" : 523, "envelopeEnd" : 562, "postProcessed" : true, "location-fragments" : [ { "start" : 523, "end" : 552, "dc-status" : "CONTINUOUS" } ] }, { "start" : 650, "end" : 690, "hmmStart" : 1, "hmmEnd" : 42, "hmmLength" : 42, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-8, "score" : 33.2, "envelopeStart" : 650, "envelopeEnd" : 690, "postProcessed" : true, "location-fragments" : [ { "start" : 650, "end" : 690, "dc-status" : "CONTINUOUS" } ] }, { "start" : 152, "end" : 194, "hmmStart" : 1, "hmmEnd" : 42, "hmmLength" : 42, "hmmBounds" : "COMPLETE", "evalue" : 8.0E-4, "score" : 19.6, "envelopeStart" : 152, "envelopeEnd" : 194, "postProcessed" : true, "location-fragments" : [ { "start" : 152, "end" : 194, "dc-status" : "CONTINUOUS" } ] }, { "start" : 279, "end" : 317, "hmmStart" : 1, "hmmEnd" : 42, "hmmLength" : 42, "hmmBounds" : "COMPLETE", "evalue" : 6.0E-6, "score" : 26.4, "envelopeStart" : 279, "envelopeEnd" : 317, "postProcessed" : true, "location-fragments" : [ { "start" : 279, "end" : 317, "dc-status" : "CONTINUOUS" } ] }, { "start" : 440, "end" : 476, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 42, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.2E-8, "score" : 34.1, "envelopeStart" : 440, "envelopeEnd" : 482, "postProcessed" : true, "location-fragments" : [ { "start" : 440, "end" : 476, "dc-status" : "CONTINUOUS" } ] }, { "start" : 359, "end" : 393, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 42, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.2E-7, "score" : 29.5, "envelopeStart" : 359, "envelopeEnd" : 398, "postProcessed" : true, "location-fragments" : [ { "start" : 359, "end" : 393, "dc-status" : "CONTINUOUS" } ] }, { "start" : 765, "end" : 794, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 42, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.7E-5, "score" : 24.3, "envelopeStart" : 765, "envelopeEnd" : 804, "postProcessed" : true, "location-fragments" : [ { "start" : 765, "end" : 794, "dc-status" : "CONTINUOUS" } ] }, { "start" : 401, "end" : 438, "hmmStart" : 2, "hmmEnd" : 42, "hmmLength" : 42, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 6.4E-4, "score" : 19.9, "envelopeStart" : 400, "envelopeEnd" : 438, "postProcessed" : true, "location-fragments" : [ { "start" : 401, "end" : 438, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1078, "end" : 1109, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 42, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.2E-5, "score" : 24.5, "envelopeStart" : 1078, "envelopeEnd" : 1117, "postProcessed" : true, "location-fragments" : [ { "start" : 1078, "end" : 1109, "dc-status" : "CONTINUOUS" } ] }, { "start" : 237, "end" : 277, "hmmStart" : 1, "hmmEnd" : 42, "hmmLength" : 42, "hmmBounds" : "COMPLETE", "evalue" : 2.0E-4, "score" : 21.5, "envelopeStart" : 237, "envelopeEnd" : 277, "postProcessed" : true, "location-fragments" : [ { "start" : 237, "end" : 277, "dc-status" : "CONTINUOUS" } ] }, { "start" : 319, "end" : 357, "hmmStart" : 1, "hmmEnd" : 42, "hmmLength" : 42, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-8, "score" : 34.1, "envelopeStart" : 319, "envelopeEnd" : 357, "postProcessed" : true, "location-fragments" : [ { "start" : 319, "end" : 357, "dc-status" : "CONTINUOUS" } ] }, { "start" : 958, "end" : 989, "hmmStart" : 1, "hmmEnd" : 32, "hmmLength" : 42, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.1E-7, "score" : 30.5, "envelopeStart" : 958, "envelopeEnd" : 998, "postProcessed" : true, "location-fragments" : [ { "start" : 958, "end" : 989, "dc-status" : "CONTINUOUS" } ] }, { "start" : 853, "end" : 893, "hmmStart" : 1, "hmmEnd" : 40, "hmmLength" : 42, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.0E-4, "score" : 21.5, "envelopeStart" : 853, "envelopeEnd" : 905, "postProcessed" : true, "location-fragments" : [ { "start" : 853, "end" : 893, "dc-status" : "CONTINUOUS" } ] }, { "start" : 605, "end" : 648, "hmmStart" : 1, "hmmEnd" : 42, "hmmLength" : 42, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-5, "score" : 24.9, "envelopeStart" : 605, "envelopeEnd" : 648, "postProcessed" : true, "location-fragments" : [ { "start" : 605, "end" : 648, "dc-status" : "CONTINUOUS" } ] }, { "start" : 196, "end" : 231, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 42, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 7.1E-6, "score" : 26.1, "envelopeStart" : 196, "envelopeEnd" : 235, "postProcessed" : true, "location-fragments" : [ { "start" : 196, "end" : 231, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-45, "score" : 150.7, "model-ac" : "PF07645" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2133, "end" : 2170, "score" : 6.961, "alignment" : "-LDPCPGACGIGASCRVEKH--HPQCVCDSGLTGnplIKCV", "location-fragments" : [ { "start" : 2133, "end" : 2170, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 220, "end" : 278, "hmmStart" : 613, "hmmEnd" : 673, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 217, "envelopeEnd" : 281, "location-fragments" : [ { "start" : 220, "end" : 278, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1988, "end" : 2026, "score" : 9.616, "alignment" : "KRNRCEpNPCGHGAICDPNQA---QSCFCPEPLIGnpyRSCT", "location-fragments" : [ { "start" : 1988, "end" : 2026, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SSF57184", "name" : "Growth factor receptor domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009030", "name" : "Growth_fac_rcpt_cys_sf", "description" : "Growth factor receptor cysteine-rich domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 165, "end" : 283, "hmmLength" : 155, "location-fragments" : [ { "start" : 165, "end" : 283, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.55E-10, "model-ac" : "0053854" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 6432, "end" : 6451, "location-fragments" : [ { "start" : 6432, "end" : 6451, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4907, "end" : 4946, "score" : 7.845, "alignment" : "-VNPCAvsTPCAPSAECQADNH--RAMCKCPPGLVGdpfVNCY", "location-fragments" : [ { "start" : 4907, "end" : 4946, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1861, "end" : 1900, "score" : 12.043, "alignment" : "PTNPCNpNPCGYQALCEVDEG--NPICFCPKGMTGnpfKTCI", "location-fragments" : [ { "start" : 1861, "end" : 1900, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 765, "end" : 805, "score" : 15.941, "alignment" : "DIDECDnNPCPIGAVCHNEPG--SFSCKCPGGTVGdpfkQGCS", "location-fragments" : [ { "start" : 765, "end" : 805, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SSF90148", "name" : "DPY module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 4146, "end" : 4169, "hmmLength" : 24, "location-fragments" : [ { "start" : 4146, "end" : 4169, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.35E-5, "model-ac" : "0048576" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5425, "end" : 5464, "score" : 9.872, "alignment" : "-VNPCIleDACAPNAECYGDNH--QTACRCAPGYEGnplVRCE", "location-fragments" : [ { "start" : 5425, "end" : 5464, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2531, "end" : 2544, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M6I1M", "alignment" : "CsClpGYrgvppvC", "location-fragments" : [ { "start" : 2531, "end" : 2544, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 457, "end" : 468, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CeNtdpgFtCtC", "location-fragments" : [ { "start" : 457, "end" : 468, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1078, "end" : 1114, "score" : 19.259, "alignment" : "DIDECVnSPCVAGAKCINEHG--SYRCDCPKGVTGEGCA", "location-fragments" : [ { "start" : 1078, "end" : 1114, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 262, "end" : 277, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M8I1M", "alignment" : "CeCprGYegdayrgvC", "location-fragments" : [ { "start" : 262, "end" : 277, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1039, "end" : 1115, "hmmStart" : 5, "hmmEnd" : 84, "hmmLength" : 95, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.9E-10, "score" : 42.7, "envelopeStart" : 1039, "envelopeEnd" : 1116, "postProcessed" : true, "location-fragments" : [ { "start" : 1039, "end" : 1115, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-138, "score" : 452.2, "model-ac" : "4d90A02" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1739, "end" : 1859, "hmmStart" : 3491, "hmmEnd" : 3609, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1734, "envelopeEnd" : 1862, "location-fragments" : [ { "start" : 1739, "end" : 1859, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 975, "end" : 986, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CiNkrggYeClC", "location-fragments" : [ { "start" : 975, "end" : 986, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "SM00289", "name" : "WR1_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006150", "name" : "Cys_repeat_1", "description" : "Cysteine-rich repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1074, "end" : 1105, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 55.0, "score" : 3.9, "location-fragments" : [ { "start" : 1074, "end" : 1105, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1377, "end" : 1405, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 28.0, "score" : 6.9, "location-fragments" : [ { "start" : 1377, "end" : 1405, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5847, "end" : 5880, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 76.0, "score" : 2.5, "location-fragments" : [ { "start" : 5847, "end" : 5880, "dc-status" : "CONTINUOUS" } ] }, { "start" : 761, "end" : 792, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 49.0, "score" : 4.5, "location-fragments" : [ { "start" : 761, "end" : 792, "dc-status" : "CONTINUOUS" } ] }, { "start" : 396, "end" : 427, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 99.0, "score" : 1.2, "location-fragments" : [ { "start" : 396, "end" : 427, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5337, "end" : 5370, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 100.0, "score" : 1.1, "location-fragments" : [ { "start" : 5337, "end" : 5370, "dc-status" : "CONTINUOUS" } ] }, { "start" : 480, "end" : 511, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 43.0, "score" : 5.1, "location-fragments" : [ { "start" : 480, "end" : 511, "dc-status" : "CONTINUOUS" } ] }, { "start" : 909, "end" : 945, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 3.6, "score" : 16.4, "location-fragments" : [ { "start" : 909, "end" : 945, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1306, "end" : 1336, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 81.0, "score" : 2.1, "location-fragments" : [ { "start" : 1306, "end" : 1336, "dc-status" : "CONTINUOUS" } ] }, { "start" : 802, "end" : 839, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 59.0, "score" : 3.6, "location-fragments" : [ { "start" : 802, "end" : 839, "dc-status" : "CONTINUOUS" } ] }, { "start" : 688, "end" : 717, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 51.0, "score" : 4.3, "location-fragments" : [ { "start" : 688, "end" : 717, "dc-status" : "CONTINUOUS" } ] }, { "start" : 355, "end" : 387, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 51.0, "score" : 4.2, "location-fragments" : [ { "start" : 355, "end" : 387, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-12, "score" : 55.7, "model-ac" : "SM00289" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 523, "end" : 559, "score" : 12.298, "alignment" : "DIDECLsLPCGPFSVCNNTQG--SFQCSCIPGNVGAPPK", "location-fragments" : [ { "start" : 523, "end" : 559, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4793, "end" : 4807, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CqCppGFvgnpyrsC", "location-fragments" : [ { "start" : 4793, "end" : 4807, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 400, "end" : 439, "score" : 17.117, "alignment" : "NVNECSaNPCGENAVCTDTVG--SFVCSCRQDYTGdpyRKCV", "location-fragments" : [ { "start" : 400, "end" : 439, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4061, "end" : 4098, "score" : 7.181, "alignment" : "-VNPCLGICGQDARCDVINH--APSCSCPPGLTGnplAACR", "location-fragments" : [ { "start" : 4061, "end" : 4098, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SSF57196", "name" : "EGF/Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 951, "end" : 991, "hmmLength" : 53, "location-fragments" : [ { "start" : 951, "end" : 991, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.58E-5, "model-ac" : "0045804" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3790, "end" : 3828, "score" : 13.307, "alignment" : "LVDPCTpSPCGPNSQCRKANN--QPVCSCLPEYKGapPNCQ", "location-fragments" : [ { "start" : 3790, "end" : 3828, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3958, "end" : 3995, "score" : 10.422, "alignment" : "-RDPCIGSCSNNAECRVQNH--APVCSCVEGYSGdpfSQCS", "location-fragments" : [ { "start" : 3958, "end" : 3995, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1862, "end" : 1938, "hmmStart" : 862, "hmmEnd" : 943, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1859, "envelopeEnd" : 1943, "location-fragments" : [ { "start" : 1862, "end" : 1938, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3043, "end" : 3784, "hmmStart" : 1246, "hmmEnd" : 2021, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3034, "envelopeEnd" : 3789, "location-fragments" : [ { "start" : 3043, "end" : 3784, "dc-status" : "CONTINUOUS" } ] }, { "start" : 279, "end" : 364, "hmmStart" : 76, "hmmEnd" : 159, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 278, "envelopeEnd" : 370, "location-fragments" : [ { "start" : 279, "end" : 364, "dc-status" : "CONTINUOUS" } ] }, { "start" : 618, "end" : 678, "hmmStart" : 122, "hmmEnd" : 184, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 613, "envelopeEnd" : 680, "location-fragments" : [ { "start" : 618, "end" : 678, "dc-status" : "CONTINUOUS" } ] }, { "start" : 357, "end" : 612, "hmmStart" : 70, "hmmEnd" : 326, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 355, "envelopeEnd" : 618, "location-fragments" : [ { "start" : 357, "end" : 612, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1204, "end" : 1373, "hmmStart" : 2487, "hmmEnd" : 2639, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1203, "envelopeEnd" : 1379, "location-fragments" : [ { "start" : 1204, "end" : 1373, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 359, "end" : 399, "score" : 17.765, "alignment" : "DINECDnpNQCGINAKCMNTPG--SYVCVCPEGFSGhgqIYCE", "location-fragments" : [ { "start" : 359, "end" : 399, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1944, "end" : 1986, "score" : 9.791, "alignment" : "PKNPCSpSPCGPNTQCSLLSD-GFAKCTCLPGYVEspntiRGCV", "location-fragments" : [ { "start" : 1944, "end" : 1986, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 813, "end" : 894, "hmmStart" : 16, "hmmEnd" : 70, "hmmLength" : 75, "hmmBounds" : "COMPLETE", "evalue" : 5.3E-9, "score" : 38.0, "envelopeStart" : 813, "envelopeEnd" : 894, "postProcessed" : true, "location-fragments" : [ { "start" : 813, "end" : 894, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-114, "score" : 375.3, "model-ac" : "3p5bL01" }, { "signature" : { "accession" : "PS01187", "name" : "EGF_CA", "description" : "Calcium-binding EGF-like domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018097", "name" : "EGF_Ca-bd_CS", "description" : "EGF-like calcium-binding, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 359, "end" : 384, "level" : "STRONG", "cigarAlignment" : "1M1I3M5I1M5I1M1I1M4I1M1I1M", "alignment" : "DiNECdnpnqCginakCmNtpgsYvC", "location-fragments" : [ { "start" : 359, "end" : 384, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01187" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 212, "end" : 223, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CtNtpgnYtCdC", "location-fragments" : [ { "start" : 212, "end" : 223, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 5931, "end" : 6428, "hmmStart" : 3973, "hmmEnd" : 4330, "hmmLength" : 4330, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 5923, "envelopeEnd" : 6428, "location-fragments" : [ { "start" : 5931, "end" : 6428, "dc-status" : "CONTINUOUS" } ] }, { "start" : 220, "end" : 278, "hmmStart" : 613, "hmmEnd" : 673, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 217, "envelopeEnd" : 281, "location-fragments" : [ { "start" : 220, "end" : 278, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 294, "end" : 305, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CrNepgtFqCsC", "location-fragments" : [ { "start" : 294, "end" : 305, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1040, "end" : 1077, "score" : 6.886, "alignment" : "-KSPCEmLSCGINAECNPHDP---PRCVCRPGFTGdplLGCI", "location-fragments" : [ { "start" : 1040, "end" : 1077, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 375, "end" : 386, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CmNtpgsYvCvC", "location-fragments" : [ { "start" : 375, "end" : 386, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PS01187", "name" : "EGF_CA", "description" : "Calcium-binding EGF-like domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018097", "name" : "EGF_Ca-bd_CS", "description" : "EGF-like calcium-binding, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 650, "end" : 674, "level" : "STRONG", "cigarAlignment" : "1M1I3M4I1M5I1M1I1M4I1M1I1M", "alignment" : "DiDECqqnpCgegalCeNtvgsFeC", "location-fragments" : [ { "start" : 650, "end" : 674, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01187" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1944, "end" : 2069, "hmmStart" : 793, "hmmEnd" : 947, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1940, "envelopeEnd" : 2073, "location-fragments" : [ { "start" : 1944, "end" : 2069, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5706, "end" : 5720, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CrCvsGYrgdpydrC", "location-fragments" : [ { "start" : 5706, "end" : 5720, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 917, "end" : 957, "score" : 8.242, "alignment" : "VLAGCDnGQCPNGAECITIAG-QVSYCACPKGFRRqedGVCE", "location-fragments" : [ { "start" : 917, "end" : 957, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SSF57196", "name" : "EGF/Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 113, "end" : 159, "hmmLength" : 55, "location-fragments" : [ { "start" : 113, "end" : 159, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.01E-8, "model-ac" : "0053580" }, { "signature" : { "accession" : "SSF90148", "name" : "DPY module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 4472, "end" : 4495, "hmmLength" : 24, "location-fragments" : [ { "start" : 4472, "end" : 4495, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.45E-5, "model-ac" : "0048576" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5449, "end" : 5463, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CrCapGYegnplvrC", "location-fragments" : [ { "start" : 5449, "end" : 5463, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6043, "end" : 6057, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "ClCiaGYngdpysvC", "location-fragments" : [ { "start" : 6043, "end" : 6057, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1718, "end" : 1732, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CgCieGYegnayvgC", "location-fragments" : [ { "start" : 1718, "end" : 1732, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 726, "end" : 761, "score" : 9.901, "alignment" : "-VNPCDaVSCGTNAECVISNN--EPSCVCSPGFTGTTPD", "location-fragments" : [ { "start" : 726, "end" : 761, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 958, "end" : 999, "score" : 14.333, "alignment" : "DIDECAeiaQACGYGAECINKRG--GYECLCNQGTSGdpyILCS", "location-fragments" : [ { "start" : 958, "end" : 999, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3980, "end" : 3994, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CsCveGYsgdpfsqC", "location-fragments" : [ { "start" : 3980, "end" : 3994, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3018, "end" : 3032, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CsCfdGYqgdpftrC", "location-fragments" : [ { "start" : 3018, "end" : 3032, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 3043, "end" : 3784, "hmmStart" : 1246, "hmmEnd" : 2021, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3034, "envelopeEnd" : 3789, "location-fragments" : [ { "start" : 3043, "end" : 3784, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2071, "end" : 2279, "hmmStart" : 793, "hmmEnd" : 1006, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2069, "envelopeEnd" : 2290, "location-fragments" : [ { "start" : 2071, "end" : 2279, "dc-status" : "CONTINUOUS" } ] }, { "start" : 670, "end" : 1084, "hmmStart" : 340, "hmmEnd" : 780, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 668, "envelopeEnd" : 1085, "location-fragments" : [ { "start" : 670, "end" : 1084, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2350, "end" : 2387, "score" : 9.282, "alignment" : "-MDPCSGSCGFGAQCTVHHH--QPICTCPQGLVGnpfEHCH", "location-fragments" : [ { "start" : 2350, "end" : 2387, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3321, "end" : 3358, "score" : 8.961, "alignment" : "-TDPCPGSCGVNAQCQVLNH--VPTCSCMEGFTGdsfVHCS", "location-fragments" : [ { "start" : 3321, "end" : 3358, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4973, "end" : 5012, "score" : 7.546, "alignment" : "-QDPCIlsNLCGAGAQCSVSMH--RPVCDCPADWAGdpqVQCY", "location-fragments" : [ { "start" : 4973, "end" : 5012, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3343, "end" : 3357, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CsCmeGFtgdsfvhC", "location-fragments" : [ { "start" : 3343, "end" : 3357, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4432, "end" : 4468, "score" : 9.965, "alignment" : "LSSPCSrSPCGPNAVCRVINN--AAMCECLPDFYGSPSD", "location-fragments" : [ { "start" : 4432, "end" : 4468, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SSF57184", "name" : "Growth factor receptor domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009030", "name" : "Growth_fac_rcpt_cys_sf", "description" : "Growth factor receptor cysteine-rich domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 357, "end" : 484, "hmmLength" : 155, "location-fragments" : [ { "start" : 357, "end" : 484, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-12, "model-ac" : "0053854" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2506, "end" : 2545, "score" : 13.042, "alignment" : "PSNPCDpSPCGPNSRCLISKQ-GYASCSCLPGYRGvpPVCK", "location-fragments" : [ { "start" : 2506, "end" : 2545, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SSF57196", "name" : "EGF/Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 1075, "end" : 1114, "hmmLength" : 53, "location-fragments" : [ { "start" : 1075, "end" : 1114, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.46E-7, "model-ac" : "0045804" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 665, "end" : 676, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CeNtvgsFeCsC", "location-fragments" : [ { "start" : 665, "end" : 676, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 113, "end" : 151, "score" : 16.391, "alignment" : "DENECKyRPCDVFAHCTNTLG--SFHCSCFPGYTGngFYCQ", "location-fragments" : [ { "start" : 113, "end" : 151, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1116, "end" : 1192, "hmmStart" : 2, "hmmEnd" : 67, "hmmLength" : 73, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 8.0E-5, "score" : 25.1, "envelopeStart" : 1115, "envelopeEnd" : 1192, "postProcessed" : true, "location-fragments" : [ { "start" : 1116, "end" : 1192, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-102, "score" : 336.4, "model-ac" : "1tozA02" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 303, "end" : 317, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CsCpqGFagdpfssC", "location-fragments" : [ { "start" : 303, "end" : 317, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1115, "end" : 1152, "score" : 8.091, "alignment" : "--DRCSrNPCGENTRCRDVNN--GYECSCLPGCSGdplKGCN", "location-fragments" : [ { "start" : 1115, "end" : 1152, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4108, "end" : 4146, "score" : 11.612, "alignment" : "AGDLCNpNPCGPNSICRITNG--FAVCSCQPGLIGspPLCR", "location-fragments" : [ { "start" : 4108, "end" : 4146, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 158, "end" : 198, "hmmStart" : 9, "hmmEnd" : 48, "hmmLength" : 50, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.1E-8, "score" : 35.7, "envelopeStart" : 158, "envelopeEnd" : 201, "postProcessed" : true, "location-fragments" : [ { "start" : 158, "end" : 198, "dc-status" : "CONTINUOUS" } ] }, { "start" : 280, "end" : 322, "hmmStart" : 2, "hmmEnd" : 48, "hmmLength" : 50, "hmmBounds" : "INCOMPLETE", "evalue" : 4.6E-11, "score" : 44.8, "envelopeStart" : 279, "envelopeEnd" : 325, "postProcessed" : true, "location-fragments" : [ { "start" : 280, "end" : 322, "dc-status" : "CONTINUOUS" } ] }, { "start" : 112, "end" : 157, "hmmStart" : 2, "hmmEnd" : 48, "hmmLength" : 50, "hmmBounds" : "COMPLETE", "evalue" : 8.5E-13, "score" : 50.3, "envelopeStart" : 112, "envelopeEnd" : 157, "postProcessed" : true, "location-fragments" : [ { "start" : 112, "end" : 157, "dc-status" : "CONTINUOUS" } ] }, { "start" : 323, "end" : 361, "hmmStart" : 2, "hmmEnd" : 48, "hmmLength" : 50, "hmmBounds" : "INCOMPLETE", "evalue" : 1.2E-11, "score" : 46.7, "envelopeStart" : 319, "envelopeEnd" : 364, "postProcessed" : true, "location-fragments" : [ { "start" : 323, "end" : 361, "dc-status" : "CONTINUOUS" } ] }, { "start" : 918, "end" : 959, "hmmStart" : 6, "hmmEnd" : 48, "hmmLength" : 50, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.1E-6, "score" : 28.4, "envelopeStart" : 918, "envelopeEnd" : 963, "postProcessed" : true, "location-fragments" : [ { "start" : 918, "end" : 959, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-164, "score" : 535.1, "model-ac" : "1yo8A01" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3923, "end" : 3936, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M6I1M", "alignment" : "CsClhGFigtapnC", "location-fragments" : [ { "start" : 3923, "end" : 3936, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1763, "end" : 1801, "score" : 7.365, "alignment" : "-VNPCFeDSCGLNAVCIPVNH--GTDCRCLAGFHGnpyLGCT", "location-fragments" : [ { "start" : 1763, "end" : 1801, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2831, "end" : 2869, "score" : 9.067, "alignment" : "PKNPCEsAMCGPNSICRVSDG--HAVCSCQRDFVGtpPACR", "location-fragments" : [ { "start" : 2831, "end" : 2869, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1434, "end" : 1572, "hmmStart" : 2850, "hmmEnd" : 2985, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1431, "envelopeEnd" : 1579, "location-fragments" : [ { "start" : 1434, "end" : 1572, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "SSF90148", "name" : "DPY module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 4040, "end" : 4063, "hmmLength" : 24, "location-fragments" : [ { "start" : 4040, "end" : 4063, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.14E-5, "model-ac" : "0048576" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4773, "end" : 4808, "score" : 8.416, "alignment" : "-VNPCI--CANNALCIVISH--NPTCQCPPGFVGnpyRSCV", "location-fragments" : [ { "start" : 4773, "end" : 4808, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 942, "end" : 956, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CaCpkGFrrqedgvC", "location-fragments" : [ { "start" : 942, "end" : 956, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2890, "end" : 2927, "score" : 6.944, "alignment" : "-VDPCPGTCGVQAVCQVLNH--NPMCSCPPSTTGdpfVKCV", "location-fragments" : [ { "start" : 2890, "end" : 2927, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 605, "end" : 649, "score" : 11.964, "alignment" : "DINECDqvhgvnGQCGLNSICTNSLG--GFNCECQQGYSGnpfKQCF", "location-fragments" : [ { "start" : 605, "end" : 649, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4712, "end" : 4751, "score" : 10.606, "alignment" : "-VNPCTfSQCGVNAECHPDNN-HRARCSCPASFTGdplVKCE", "location-fragments" : [ { "start" : 4712, "end" : 4751, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2292, "end" : 2831, "hmmStart" : 1476, "hmmEnd" : 2025, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2280, "envelopeEnd" : 2833, "location-fragments" : [ { "start" : 2292, "end" : 2831, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1079, "end" : 1194, "hmmStart" : 77, "hmmEnd" : 191, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1077, "envelopeEnd" : 1197, "location-fragments" : [ { "start" : 1079, "end" : 1194, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 196, "end" : 236, "score" : 14.419, "alignment" : "DIDECLqpNACGINTVCTNTPG--NYTCDCQTGYQGnpyNGCV", "location-fragments" : [ { "start" : 196, "end" : 236, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1202, "end" : 1241, "score" : 10.474, "alignment" : "IPVDCRvSGCGKGAHCVLVGS--DYSCQCPPGTVGnpnKDCI", "location-fragments" : [ { "start" : 1202, "end" : 1241, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 650, "end" : 676, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 667, "end" : 667, "residue" : "N" }, { "start" : 650, "end" : 650, "residue" : "D" }, { "start" : 653, "end" : 653, "residue" : "E" } ] } ], "evalue" : 0.0053541, "score" : 35.6902, "location-fragments" : [ { "start" : 650, "end" : 676, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PTHR22963", "name" : "ENDOGLIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2829, "end" : 3037, "hmmStart" : 1245, "hmmEnd" : 1457, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2827, "envelopeEnd" : 3045, "location-fragments" : [ { "start" : 2829, "end" : 3037, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 538, "end" : 549, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CnNtqgsFqCsC", "location-fragments" : [ { "start" : 538, "end" : 549, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 960, "end" : 1000, "hmmStart" : 2, "hmmEnd" : 39, "hmmLength" : 45, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 6.4E-8, "score" : 34.6, "envelopeStart" : 955, "envelopeEnd" : 1000, "postProcessed" : true, "location-fragments" : [ { "start" : 960, "end" : 1000, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.4E-80, "score" : 265.1, "model-ac" : "4d0eA01" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4856, "end" : 5921, "hmmStart" : 2759, "hmmEnd" : 3810, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4855, "envelopeEnd" : 5934, "location-fragments" : [ { "start" : 4856, "end" : 5921, "dc-status" : "CONTINUOUS" } ] }, { "start" : 279, "end" : 364, "hmmStart" : 76, "hmmEnd" : 159, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 278, "envelopeEnd" : 370, "location-fragments" : [ { "start" : 279, "end" : 364, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3044, "end" : 3083, "score" : 10.91, "alignment" : "QTDPCFpTPCGVNADCVNNKG--VASCVCLSGFYGnphSGCH", "location-fragments" : [ { "start" : 3044, "end" : 3083, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4275, "end" : 4312, "score" : 8.574, "alignment" : "-ADPCPGSCGSNARCSVINH--SPMCACLSGYSGdpfTGCS", "location-fragments" : [ { "start" : 4275, "end" : 4312, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 180, "end" : 194, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CkCrpGFegdgeveC", "location-fragments" : [ { "start" : 180, "end" : 194, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2937, "end" : 2975, "score" : 12.231, "alignment" : "SINPCVpSPCGANSECHITER--GAMCSCVPGMLGapPHCR", "location-fragments" : [ { "start" : 2937, "end" : 2975, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1694, "end" : 1733, "score" : 7.716, "alignment" : "-QHPCDvhNPCAQNAICSNTNH--GASCGCIEGYEGnayVGCT", "location-fragments" : [ { "start" : 1694, "end" : 1733, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1062, "end" : 1076, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CvCrpGFtgdpllgC", "location-fragments" : [ { "start" : 1062, "end" : 1076, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1128, "end" : 1139, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CrDvnngYeCsC", "location-fragments" : [ { "start" : 1128, "end" : 1139, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4864, "end" : 4878, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CqClpGYvgdasvqC", "location-fragments" : [ { "start" : 4864, "end" : 4878, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 196, "end" : 229, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 196, "end" : 196, "residue" : "D" }, { "start" : 199, "end" : 199, "residue" : "E" }, { "start" : 214, "end" : 214, "residue" : "N" } ] } ], "evalue" : 9.37854E-5, "score" : 40.6978, "location-fragments" : [ { "start" : 196, "end" : 229, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 634, "end" : 648, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CeCqqGYsgnpfkqC", "location-fragments" : [ { "start" : 634, "end" : 648, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "SSF57196", "name" : "EGF/Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 516, "end" : 563, "hmmLength" : 53, "location-fragments" : [ { "start" : 516, "end" : 563, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.63E-7, "model-ac" : "0045804" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 279, "end" : 312, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 296, "end" : 296, "residue" : "N" }, { "start" : 279, "end" : 279, "residue" : "D" }, { "start" : 282, "end" : 282, "residue" : "E" } ] } ], "evalue" : 0.0019031, "score" : 37.231, "location-fragments" : [ { "start" : 279, "end" : 312, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "SSF90148", "name" : "DPY module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 4563, "end" : 4585, "hmmLength" : 24, "location-fragments" : [ { "start" : 4563, "end" : 4585, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.58E-5, "model-ac" : "0048576" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 384, "end" : 398, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CvCpeGFsghgqiyC", "location-fragments" : [ { "start" : 384, "end" : 398, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4583, "end" : 4620, "score" : 7.804, "alignment" : "-SDPCYDACGVNAICHAVNH--QPVCFCPPGFTGepqVLCK", "location-fragments" : [ { "start" : 4583, "end" : 4620, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2239, "end" : 2278, "score" : 9.289, "alignment" : "-KDPCSlgNVCGVGAVCISKDH--VVTCVCQKGYSGdpfIQCI", "location-fragments" : [ { "start" : 2239, "end" : 2278, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3682, "end" : 3721, "score" : 10.479, "alignment" : "LTNPCTpSPCGPNAYCRQQKN--AGSCICIPDYHGnpyEGCR", "location-fragments" : [ { "start" : 3682, "end" : 3721, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1383, "end" : 1440, "hmmStart" : 2187, "hmmEnd" : 2243, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1375, "envelopeEnd" : 1441, "location-fragments" : [ { "start" : 1383, "end" : 1440, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1158, "end" : 1267, "hmmStart" : 862, "hmmEnd" : 970, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1152, "envelopeEnd" : 1268, "location-fragments" : [ { "start" : 1158, "end" : 1267, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "SSF57184", "name" : "Growth factor receptor domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009030", "name" : "Growth_fac_rcpt_cys_sf", "description" : "Growth factor receptor cysteine-rich domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 562, "end" : 696, "hmmLength" : 155, "location-fragments" : [ { "start" : 562, "end" : 696, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.14E-9, "model-ac" : "0053854" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1204, "end" : 1373, "hmmStart" : 2487, "hmmEnd" : 2639, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1203, "envelopeEnd" : 1379, "location-fragments" : [ { "start" : 1204, "end" : 1373, "dc-status" : "CONTINUOUS" } ] }, { "start" : 5931, "end" : 6428, "hmmStart" : 3973, "hmmEnd" : 4330, "hmmLength" : 4330, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 5923, "envelopeEnd" : 6428, "location-fragments" : [ { "start" : 5931, "end" : 6428, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2829, "end" : 3037, "hmmStart" : 1245, "hmmEnd" : 1457, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2827, "envelopeEnd" : 3045, "location-fragments" : [ { "start" : 2829, "end" : 3037, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "SSF90148", "name" : "DPY module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 4363, "end" : 4386, "hmmLength" : 24, "location-fragments" : [ { "start" : 4363, "end" : 4386, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.81E-6, "model-ac" : "0048576" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 650, "end" : 692, "hmmStart" : 3, "hmmEnd" : 42, "hmmLength" : 45, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.0E-10, "score" : 43.5, "envelopeStart" : 649, "envelopeEnd" : 692, "postProcessed" : true, "location-fragments" : [ { "start" : 650, "end" : 692, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-80, "score" : 265.5, "model-ac" : "2w86A01" }, { "signature" : { "accession" : "PTHR22963:SF29", "name" : "DUMPY, ISOFORM Q", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1862, "end" : 1938, "hmmStart" : 862, "hmmEnd" : 943, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1859, "envelopeEnd" : 1943, "location-fragments" : [ { "start" : 1862, "end" : 1938, "dc-status" : "CONTINUOUS" } ] }, { "start" : 618, "end" : 678, "hmmStart" : 122, "hmmEnd" : 184, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 613, "envelopeEnd" : 680, "location-fragments" : [ { "start" : 618, "end" : 678, "dc-status" : "CONTINUOUS" } ] }, { "start" : 357, "end" : 612, "hmmStart" : 70, "hmmEnd" : 326, "hmmLength" : 4330, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 355, "envelopeEnd" : 618, "location-fragments" : [ { "start" : 357, "end" : 612, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "DUMPY, ISOFORM Q", "score" : 6082.9, "model-ac" : "PTHR22963:SF29" }, { "signature" : { "accession" : "G3DSA:2.10.25.10", "name" : "Laminin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 563, "end" : 649, "hmmStart" : 8, "hmmEnd" : 81, "hmmLength" : 82, "hmmBounds" : "COMPLETE", "evalue" : 8.1E-10, "score" : 40.8, "envelopeStart" : 563, "envelopeEnd" : 649, "postProcessed" : true, "location-fragments" : [ { "start" : 563, "end" : 649, "dc-status" : "CONTINUOUS" } ] }, { "start" : 484, "end" : 557, "hmmStart" : 8, "hmmEnd" : 73, "hmmLength" : 82, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.0E-7, "score" : 31.9, "envelopeStart" : 481, "envelopeEnd" : 557, "postProcessed" : true, "location-fragments" : [ { "start" : 484, "end" : 557, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-168, "score" : 549.8, "model-ac" : "1emoA00" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 128, "end" : 139, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CtNtlgsFhCsC", "location-fragments" : [ { "start" : 128, "end" : 139, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 279, "end" : 318, "score" : 15.399, "alignment" : "DINECLhNVCGINAICRNEPG--TFQCSCPQGFAGdpfSSCT", "location-fragments" : [ { "start" : 279, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4167, "end" : 4204, "score" : 8.572, "alignment" : "-ADPCTGTCGVNAECRVINH--SPICSCEPGHTGdpfRQCY", "location-fragments" : [ { "start" : 4167, "end" : 4204, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2724, "end" : 2761, "score" : 9.929, "alignment" : "PTNPCTpSPCGENAHCTSVDG--TARCTCIPPYVGnPYAG", "location-fragments" : [ { "start" : 2724, "end" : 2761, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 237, "end" : 278, "score" : 14.122, "alignment" : "DLNECEykGACGLGALCTNLPG--GHHCECPRGYEGdayrGVCT", "location-fragments" : [ { "start" : 237, "end" : 278, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PS01186", "name" : "EGF_2", "description" : "EGF-like domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2588, "end" : 2602, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I2M7I1M", "alignment" : "CnCapGYvgdpfinC", "location-fragments" : [ { "start" : 2588, "end" : 2602, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01186" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 415, "end" : 426, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CtDtvgsFvCsC", "location-fragments" : [ { "start" : 415, "end" : 426, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "PS00010", "name" : "ASX_HYDROXYL", "description" : "Aspartic acid and asparagine hydroxylation site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000152", "name" : "EGF-type_Asp/Asn_hydroxyl_site", "description" : "EGF-type aspartate/asparagine hydroxylation site", "type" : "PTM", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 334, "end" : 345, "level" : "STRONG", "cigarAlignment" : "1M1I1M4I1M1I1M1I1M", "alignment" : "CvNtngsFsCkC", "location-fragments" : [ { "start" : 334, "end" : 345, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00010" }, { "signature" : { "accession" : "SSF57184", "name" : "Growth factor receptor domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009030", "name" : "Growth_fac_rcpt_cys_sf", "description" : "Growth factor receptor cysteine-rich domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 247, "end" : 364, "hmmLength" : 155, "location-fragments" : [ { "start" : 247, "end" : 364, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.36E-13, "model-ac" : "0053854" } ], "xref" : [ { "name" : "XP_018910035.1 PREDICTED: uncharacterized protein LOC109039134 [Bemisia tabaci]", "id" : "XP_018910035.1" } ] },{ "sequence" : "MTGRIEGETNLRKLDQPRGMKLSIFKRAIPWILIACVLSSLRDCSASSRALSRSNVSDGRVVYSLLAPSKATPEFAGLQTLQARCMEMLTAGLNANRAMTNTMDQYGRIMGAAMGAALSRSASARAASRRGRQSRTTFDQWTYYIRPPGGGRPIRRSVTSRSSSRSGSRSSRSSPSRSSKRSVSGRSVSKKKGRSSGSSKRGRGSPKGKRTKSPKKGTPKKGKDDDDDDDDDDDDDDDDDTPSSSPSSPARPQNLLMQPQVPRQQAPPQPQVRQSPPSPQRTLQQPPGQPNGLRQNDLPVDELVRRLEEYSRSPTPPVQPVNSPSPPRRPLSFAPGVPRPPAPARPNSPTGGRSDPNQARKPNRYILDYTKPGEMRKVETFGEPLTPSRYGLETFPTDLLHLPANEFERRAKNSKGQPQKMDGIPDDVAMAFERLPPQKRTPVRRNGLDTPSFMNGVAGHQRFR", "md5" : "451c5338519b22ec6472ad04e397b927", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 263, "end" : 284, "location-fragments" : [ { "start" : 263, "end" : 284, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 156, "end" : 183, "location-fragments" : [ { "start" : 156, "end" : 183, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 184, "end" : 217, "location-fragments" : [ { "start" : 184, "end" : 217, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 243, "end" : 262, "location-fragments" : [ { "start" : 243, "end" : 262, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 317, "end" : 347, "location-fragments" : [ { "start" : 317, "end" : 347, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 138, "end" : 371, "location-fragments" : [ { "start" : 138, "end" : 371, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 407, "end" : 464, "location-fragments" : [ { "start" : 407, "end" : 464, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 225, "end" : 242, "location-fragments" : [ { "start" : 225, "end" : 242, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910313.1 PREDICTED: arginine-glutamic acid dipeptide repeats protein-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910313.1" } ] },{ "sequence" : "MSKDETVYAASLVDTSVDSNNSLFVRSNVSDGTSLVGQSILNFSVGCDPDFDPVTFDEPVQQVLYSAEEEEEEGRHLDESPDNLLAAEAAYLADDVAMPGLDGAMTPPPVSPEAEKTETQKVEAMLAYWAVKKKITLVALNELLKGLKDSHPCFSDMHVDARTILKTPREKMPITDVPPGHLIYLGVKYHVDIMLSLLEDIVNLLRLLFYADGLQVFNSTSYQMWVLSMSAPNIPRLKHKVFPVSIYYGKGKPKDVSEFLQPFIDEVIQLFSTDDQKEECKIYMKGQRVHIETFGFGCDTPARSYLLQTVGHTGFYSCFRCTTRGLTSNKRRCFPKVDAPLRTDEKFRRRKYSKFQPKHLQLSPLLQLPGLNFTRSFINDPMHLLFQGCTKSMLKLWFKSGIPNIIDIFYRKQINEKLKYAVTFLPREFQRRPRGLESLADWKATEFRAFALYLGPVILKGSLDEADYYLHFLSFSIALIILFNPLLIKIDELINYADELLRSFVVNMSVLYGEWTVSHNIHHLIHLVEDVWFFKDSVPDFTLIDIANFFMES", "md5" : "27f9740d38c6365f8abe394e7d28aacd", "matches" : [ { "signature" : { "accession" : "PTHR33053", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 111, "end" : 537, "hmmStart" : 109, "hmmEnd" : 537, "hmmLength" : 745, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 64, "envelopeEnd" : 549, "location-fragments" : [ { "start" : 111, "end" : 537, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.1E-87, "familyName" : "FAMILY NOT NAMED", "score" : 295.3, "model-ac" : "PTHR33053" } ], "xref" : [ { "name" : "XP_018910440.1 PREDICTED: uncharacterized protein LOC109039425 [Bemisia tabaci]", "id" : "XP_018910440.1" } ] },{ "sequence" : "MPLFQRKNNKKDEVDANGRNNSTLGYEYDKSRSFYSSSMVSRNPEDLKMEPENVQKPKLVFHCQQAQGSPTGLISGFSNVKELYQKIAQCYDFSVDEILFCTLNTHKVDMTKLLGGQIGLDDFIFVHKKGRPKEVEITKTDSALGLTITDNGAGYAFIKRIKEGSIIDNIDCIQVGDHIERINKVSLVGRRHFEVAKYLKEIPKDSTFTIRLVEPLKAGFSNIEPRGNPRKGKKSNYGSGKETLRFKANGKALIEEEADGEKQAGIEKINLCLESFLGISDNELAVQIWELAEGKRNSMDFAEAIDSSDLEAFGFNDDFIIELWGGITDVRSGRIH", "md5" : "6d6abb6dd918cd49a0bdf8f1ed8579cb", "matches" : [ { "signature" : { "accession" : "SM00228", "name" : "pdz_new", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 142, "end" : 216, "hmmStart" : 1, "hmmEnd" : 80, "hmmLength" : 80, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-8, "score" : 43.5, "location-fragments" : [ { "start" : 142, "end" : 216, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-8, "score" : 43.5, "model-ac" : "SM00228" }, { "signature" : { "accession" : "cd00992", "name" : "PDZ_signaling", "description" : "PDZ_signaling", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 132, "end" : 211, "sites" : [ { "description" : "protein binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 146, "end" : 146, "residue" : "L" }, { "start" : 199, "end" : 199, "residue" : "L" }, { "start" : 145, "end" : 145, "residue" : "G" }, { "start" : 148, "end" : 148, "residue" : "I" }, { "start" : 144, "end" : 144, "residue" : "L" }, { "start" : 200, "end" : 200, "residue" : "K" }, { "start" : 196, "end" : 196, "residue" : "A" }, { "start" : 195, "end" : 195, "residue" : "V" } ] } ], "evalue" : 3.58832E-12, "score" : 59.5026, "location-fragments" : [ { "start" : 132, "end" : 211, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00992" }, { "signature" : { "accession" : "SSF50156", "name" : "PDZ domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036034", "name" : "PDZ_sf", "description" : "PDZ superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 106, "end" : 213, "hmmLength" : 130, "location-fragments" : [ { "start" : 106, "end" : 213, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.12E-17, "model-ac" : "0038828" }, { "signature" : { "accession" : "PF00595", "name" : "PDZ", "description" : "PDZ domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 135, "end" : 204, "hmmStart" : 2, "hmmEnd" : 75, "hmmLength" : 82, "hmmBounds" : "INCOMPLETE", "evalue" : 3.2E-7, "score" : 30.6, "envelopeStart" : 134, "envelopeEnd" : 213, "postProcessed" : true, "location-fragments" : [ { "start" : 135, "end" : 204, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-7, "score" : 31.4, "model-ac" : "PF00595" }, { "signature" : { "accession" : "PS50106", "name" : "PDZ", "description" : "PDZ domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 134, "end" : 214, "score" : 12.245, "alignment" : "EVEITKTDSA-LGLTITDNGAGY----AFIKRIKEGSIIDNIDCIQVGDHIERINKVSLVGRRHFEVAKYLKEIPKDSTFTIRLVE", "location-fragments" : [ { "start" : 134, "end" : 214, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50106" }, { "signature" : { "accession" : "G3DSA:2.30.42.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036034", "name" : "PDZ_sf", "description" : "PDZ superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 127, "end" : 219, "hmmStart" : 3, "hmmEnd" : 89, "hmmLength" : 95, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-21, "score" : 76.5, "envelopeStart" : 127, "envelopeEnd" : 219, "postProcessed" : true, "location-fragments" : [ { "start" : 127, "end" : 219, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-21, "score" : 77.2, "model-ac" : "3ggeA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 17, "location-fragments" : [ { "start" : 1, "end" : 17, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 22, "location-fragments" : [ { "start" : 1, "end" : 22, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12259", "name" : "RGS-GAIP INTERACTING PROTEIN GIPC", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR017379", "name" : "GIPC1/2/3", "description" : "PDZ domain-containing protein GIPC1/2/3", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 335, "hmmStart" : 1, "hmmEnd" : 337, "hmmLength" : 340, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 336, "location-fragments" : [ { "start" : 1, "end" : 335, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-140, "familyName" : "GH21964P", "score" : 469.3, "model-ac" : "PTHR12259" }, { "signature" : { "accession" : "PTHR12259:SF1", "name" : "GH21964P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 335, "hmmStart" : 1, "hmmEnd" : 337, "hmmLength" : 340, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 336, "location-fragments" : [ { "start" : 1, "end" : 335, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-140, "familyName" : "GH21964P", "score" : 469.3, "model-ac" : "PTHR12259:SF1" } ], "xref" : [ { "name" : "XP_018910132.1 PREDICTED: PDZ domain-containing protein GIPC3 [Bemisia tabaci]", "id" : "XP_018910132.1" } ] },{ "sequence" : "MVNNSQRLWRKIRKLSPVLMPPGSPGIFRRKSSSEITPLIANNNNNDKFSDVPSSKMATASANLPFVGWPNSKDDYELKEVIGVGATAVVHAALCRPRQEKCAIKRINLEKWNTSMDELLKEIQAMSSCHHENVVTYHTSFVVREELWLVLGLLGGGSLLDIIKHKMRTSDCRNGVFDESTIATVLREVLKGLEYFHSNGQIHRDIKAGNILLGDDGIVQIADFGVSAWLATGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSLGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVDCLQKDPSKRPSANELLKHPFFKKAKDRKYLQQTLVAMGPSLETRVQKAAKRQPGTSGRLHRTVTGEWVWSSEEEGDMSSDDESRVKPINNIQHSDSSGSETDLAIGDHGSDDPINLVLRMRNSKKELNDIKFEFAIGKDHSEGIASELFGAGLVDGKDVSVIATNLQTLIENHRSIKTVVFPLNSGSETERDEKTLVGFAQISITD", "md5" : "9e243004e69b04f4eb568061930ad020", "matches" : [ { "signature" : { "accession" : "PF00069", "name" : "Pkinase", "description" : "Protein kinase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 76, "end" : 350, "hmmStart" : 1, "hmmEnd" : 264, "hmmLength" : 264, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-60, "score" : 204.8, "envelopeStart" : 76, "envelopeEnd" : 350, "postProcessed" : true, "location-fragments" : [ { "start" : 76, "end" : 350, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-60, "score" : 205.2, "model-ac" : "PF00069" }, { "signature" : { "accession" : "SM00220", "name" : "serkin_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 76, "end" : 350, "hmmStart" : 1, "hmmEnd" : 231, "hmmLength" : 231, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-82, "score" : 290.1, "location-fragments" : [ { "start" : 76, "end" : 350, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-82, "score" : 290.1, "model-ac" : "SM00220" }, { "signature" : { "accession" : "G3DSA:3.30.200.20", "name" : "Phosphorylase Kinase; domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 66, "end" : 153, "hmmStart" : 5, "hmmEnd" : 88, "hmmLength" : 90, "hmmBounds" : "COMPLETE", "evalue" : 4.3E-32, "score" : 112.1, "envelopeStart" : 66, "envelopeEnd" : 153, "postProcessed" : true, "location-fragments" : [ { "start" : 66, "end" : 153, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-32, "score" : 113.0, "model-ac" : "5dbxA01" }, { "signature" : { "accession" : "PTHR24361:SF807", "name" : "FRAYED, ISOFORM A", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 66, "end" : 378, "hmmStart" : 6, "hmmEnd" : 309, "hmmLength" : 367, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 61, "envelopeEnd" : 496, "location-fragments" : [ { "start" : 66, "end" : 378, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-147, "familyName" : "FRAYED, ISOFORM A", "score" : 494.5, "model-ac" : "PTHR24361:SF807" }, { "signature" : { "accession" : "PS50011", "name" : "PROTEIN_KINASE_DOM", "description" : "Protein kinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 76, "end" : 350, "score" : 47.58, "alignment" : "YELKEVIGVGATAVVHAALCRPRQEKCAIKRINLE----KwntSMDELLKEIQAMSSCHHENVVTYHTSFVVREELWLVLGLLGGGSLLDIIKHKMRTsdcrngvFDESTIATVLREVLKGLEYFHSNGQIHRDIKAGNILLGDDGIVQIADFGVSAWLATGRDlsrqkVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSLGITAIEMATGTAPYHKYPPMKVLMLTLQND-----PPTLDTgaddkdqykaYGKTFRKMIVDCLQKDPSKRPSANELLKHPFF", "location-fragments" : [ { "start" : 76, "end" : 350, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50011" }, { "signature" : { "accession" : "G3DSA:1.10.510.10", "name" : "Transferase(Phosphotransferase) domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 155, "end" : 366, "hmmStart" : 4, "hmmEnd" : 206, "hmmLength" : 213, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-66, "score" : 226.1, "envelopeStart" : 155, "envelopeEnd" : 366, "postProcessed" : true, "location-fragments" : [ { "start" : 155, "end" : 366, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-67, "score" : 226.8, "model-ac" : "5dbxA02" }, { "signature" : { "accession" : "cd06610", "name" : "STKc_OSR1_SPAK", "description" : "STKc_OSR1_SPAK", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 74, "end" : 350, "sites" : [ { "description" : "ATP binding site", "numLocations" : 21, "siteLocations" : [ { "start" : 154, "end" : 154, "residue" : "L" }, { "start" : 158, "end" : 158, "residue" : "S" }, { "start" : 209, "end" : 209, "residue" : "G" }, { "start" : 82, "end" : 82, "residue" : "I" }, { "start" : 86, "end" : 86, "residue" : "A" }, { "start" : 135, "end" : 135, "residue" : "V" }, { "start" : 90, "end" : 90, "residue" : "V" }, { "start" : 85, "end" : 85, "residue" : "G" }, { "start" : 212, "end" : 212, "residue" : "L" }, { "start" : 153, "end" : 153, "residue" : "L" }, { "start" : 210, "end" : 210, "residue" : "N" }, { "start" : 151, "end" : 151, "residue" : "L" }, { "start" : 207, "end" : 207, "residue" : "K" }, { "start" : 84, "end" : 84, "residue" : "V" }, { "start" : 161, "end" : 161, "residue" : "D" }, { "start" : 103, "end" : 103, "residue" : "A" }, { "start" : 152, "end" : 152, "residue" : "G" }, { "start" : 223, "end" : 223, "residue" : "D" }, { "start" : 157, "end" : 157, "residue" : "G" }, { "start" : 83, "end" : 83, "residue" : "G" }, { "start" : 105, "end" : 105, "residue" : "K" } ] }, { "description" : "active site", "numLocations" : 32, "siteLocations" : [ { "start" : 154, "end" : 154, "residue" : "L" }, { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 158, "end" : 158, "residue" : "S" }, { "start" : 209, "end" : 209, "residue" : "G" }, { "start" : 278, "end" : 278, "residue" : "E" }, { "start" : 86, "end" : 86, "residue" : "A" }, { "start" : 250, "end" : 250, "residue" : "C" }, { "start" : 153, "end" : 153, "residue" : "L" }, { "start" : 205, "end" : 205, "residue" : "D" }, { "start" : 245, "end" : 245, "residue" : "F" }, { "start" : 226, "end" : 226, "residue" : "V" }, { "start" : 157, "end" : 157, "residue" : "G" }, { "start" : 83, "end" : 83, "residue" : "G" }, { "start" : 105, "end" : 105, "residue" : "K" }, { "start" : 208, "end" : 208, "residue" : "A" }, { "start" : 287, "end" : 287, "residue" : "H" }, { "start" : 82, "end" : 82, "residue" : "I" }, { "start" : 135, "end" : 135, "residue" : "V" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 90, "end" : 90, "residue" : "V" }, { "start" : 85, "end" : 85, "residue" : "G" }, { "start" : 212, "end" : 212, "residue" : "L" }, { "start" : 210, "end" : 210, "residue" : "N" }, { "start" : 151, "end" : 151, "residue" : "L" }, { "start" : 207, "end" : 207, "residue" : "K" }, { "start" : 84, "end" : 84, "residue" : "V" }, { "start" : 161, "end" : 161, "residue" : "D" }, { "start" : 222, "end" : 222, "residue" : "A" }, { "start" : 103, "end" : 103, "residue" : "A" }, { "start" : 152, "end" : 152, "residue" : "G" }, { "start" : 223, "end" : 223, "residue" : "D" }, { "start" : 248, "end" : 248, "residue" : "T" } ] }, { "description" : "activation loop (A-loop)", "numLocations" : 23, "siteLocations" : [ { "start" : 227, "end" : 227, "residue" : "S" }, { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 225, "end" : 225, "residue" : "G" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 249, "end" : 249, "residue" : "P" }, { "start" : 250, "end" : 250, "residue" : "C" }, { "start" : 228, "end" : 228, "residue" : "A" }, { "start" : 234, "end" : 234, "residue" : "R" }, { "start" : 243, "end" : 243, "residue" : "H" }, { "start" : 235, "end" : 235, "residue" : "D" }, { "start" : 233, "end" : 233, "residue" : "G" }, { "start" : 222, "end" : 222, "residue" : "A" }, { "start" : 244, "end" : 244, "residue" : "T" }, { "start" : 229, "end" : 229, "residue" : "W" }, { "start" : 230, "end" : 230, "residue" : "L" }, { "start" : 245, "end" : 245, "residue" : "F" }, { "start" : 226, "end" : 226, "residue" : "V" }, { "start" : 231, "end" : 231, "residue" : "A" }, { "start" : 223, "end" : 223, "residue" : "D" }, { "start" : 242, "end" : 242, "residue" : "R" }, { "start" : 224, "end" : 224, "residue" : "F" }, { "start" : 232, "end" : 232, "residue" : "T" }, { "start" : 248, "end" : 248, "residue" : "T" } ] }, { "description" : "dimer interface", "numLocations" : 39, "siteLocations" : [ { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 267, "end" : 267, "residue" : "A" }, { "start" : 259, "end" : 259, "residue" : "Q" }, { "start" : 278, "end" : 278, "residue" : "E" }, { "start" : 249, "end" : 249, "residue" : "P" }, { "start" : 250, "end" : 250, "residue" : "C" }, { "start" : 257, "end" : 257, "residue" : "M" }, { "start" : 256, "end" : 256, "residue" : "V" }, { "start" : 262, "end" : 262, "residue" : "G" }, { "start" : 335, "end" : 335, "residue" : "P" }, { "start" : 275, "end" : 275, "residue" : "T" }, { "start" : 263, "end" : 263, "residue" : "Y" }, { "start" : 295, "end" : 295, "residue" : "L" }, { "start" : 233, "end" : 233, "residue" : "G" }, { "start" : 254, "end" : 254, "residue" : "P" }, { "start" : 261, "end" : 261, "residue" : "H" }, { "start" : 258, "end" : 258, "residue" : "E" }, { "start" : 206, "end" : 206, "residue" : "I" }, { "start" : 232, "end" : 232, "residue" : "T" }, { "start" : 294, "end" : 294, "residue" : "V" }, { "start" : 296, "end" : 296, "residue" : "M" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 274, "end" : 274, "residue" : "I" }, { "start" : 333, "end" : 333, "residue" : "K" }, { "start" : 298, "end" : 298, "residue" : "T" }, { "start" : 270, "end" : 270, "residue" : "W" }, { "start" : 252, "end" : 252, "residue" : "M" }, { "start" : 207, "end" : 207, "residue" : "K" }, { "start" : 255, "end" : 255, "residue" : "E" }, { "start" : 291, "end" : 291, "residue" : "P" }, { "start" : 271, "end" : 271, "residue" : "S" }, { "start" : 231, "end" : 231, "residue" : "A" }, { "start" : 299, "end" : 299, "residue" : "L" }, { "start" : 284, "end" : 284, "residue" : "A" }, { "start" : 251, "end" : 251, "residue" : "W" }, { "start" : 253, "end" : 253, "residue" : "A" }, { "start" : 338, "end" : 338, "residue" : "R" }, { "start" : 336, "end" : 336, "residue" : "S" }, { "start" : 248, "end" : 248, "residue" : "T" } ] }, { "description" : "polypeptide substrate binding site", "numLocations" : 14, "siteLocations" : [ { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 208, "end" : 208, "residue" : "A" }, { "start" : 209, "end" : 209, "residue" : "G" }, { "start" : 278, "end" : 278, "residue" : "E" }, { "start" : 287, "end" : 287, "residue" : "H" }, { "start" : 86, "end" : 86, "residue" : "A" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 250, "end" : 250, "residue" : "C" }, { "start" : 85, "end" : 85, "residue" : "G" }, { "start" : 205, "end" : 205, "residue" : "D" }, { "start" : 207, "end" : 207, "residue" : "K" }, { "start" : 245, "end" : 245, "residue" : "F" }, { "start" : 226, "end" : 226, "residue" : "V" }, { "start" : 248, "end" : 248, "residue" : "T" } ] } ], "evalue" : 9.02528E-178, "score" : 499.191, "location-fragments" : [ { "start" : 74, "end" : 350, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd06610" }, { "signature" : { "accession" : "G3DSA:3.10.20.90", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 441, "end" : 534, "hmmStart" : 2, "hmmEnd" : 95, "hmmLength" : 96, "hmmBounds" : "COMPLETE", "evalue" : 5.9E-29, "score" : 102.3, "envelopeStart" : 441, "envelopeEnd" : 534, "postProcessed" : true, "location-fragments" : [ { "start" : 441, "end" : 534, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-29, "score" : 103.4, "model-ac" : "2v3sA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 400, "end" : 435, "location-fragments" : [ { "start" : 400, "end" : 435, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 418, "end" : 432, "location-fragments" : [ { "start" : 418, "end" : 432, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 58, "end" : 370, "hmmLength" : 350, "location-fragments" : [ { "start" : 58, "end" : 370, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.14E-81, "model-ac" : "0040179" }, { "signature" : { "accession" : "PTHR24361", "name" : "MITOGEN-ACTIVATED KINASE KINASE KINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 66, "end" : 378, "hmmStart" : 6, "hmmEnd" : 309, "hmmLength" : 367, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 61, "envelopeEnd" : 496, "location-fragments" : [ { "start" : 66, "end" : 378, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-147, "familyName" : "FRAYED, ISOFORM A", "score" : 494.5, "model-ac" : "PTHR24361" }, { "signature" : { "accession" : "PF12202", "name" : "OSR1_C", "description" : "Oxidative-stress-responsive kinase 1 C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR024678", "name" : "Kinase_OSR1/WNK_CCT", "description" : "Serine/threonine-protein kinase OSR1/WNK, CCT domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein serine/threonine kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004674" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Human papillomavirus infection", "databaseName" : "KEGG", "id" : "05165+2.7.11.1" }, { "name" : "PI3K-Akt signaling pathway", "databaseName" : "KEGG", "id" : "04151+2.7.11.1" }, { "name" : "Human immunodeficiency virus 1 infection", "databaseName" : "KEGG", "id" : "05170+2.7.11.1" }, { "name" : "Thermogenesis", "databaseName" : "KEGG", "id" : "04714+2.7.11.1" }, { "name" : "Relaxin signaling pathway", "databaseName" : "KEGG", "id" : "04926+2.7.11.1" }, { "name" : "Human cytomegalovirus infection", "databaseName" : "KEGG", "id" : "05163+2.7.11.1" }, { "name" : "mTOR signaling pathway", "databaseName" : "KEGG", "id" : "04150+2.7.11.1" } ] } }, "locations" : [ { "start" : 443, "end" : 499, "hmmStart" : 1, "hmmEnd" : 63, "hmmLength" : 64, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.3E-21, "score" : 74.2, "envelopeStart" : 443, "envelopeEnd" : 500, "postProcessed" : true, "location-fragments" : [ { "start" : 443, "end" : 499, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-21, "score" : 75.1, "model-ac" : "PF12202" }, { "signature" : { "accession" : "PS00107", "name" : "PROTEIN_KINASE_ATP", "description" : "Protein kinases ATP-binding region signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017441", "name" : "Protein_kinase_ATP_BS", "description" : "Protein kinase, ATP binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 82, "end" : 105, "level" : "STRONG", "cigarAlignment" : "10M1I1M8I4M", "alignment" : "IGVGATAVVHaAlcrprqekCAIK", "location-fragments" : [ { "start" : 82, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00107" } ], "xref" : [ { "name" : "XP_018909593.1 PREDICTED: serine/threonine-protein kinase OSR1 isoform X3 [Bemisia tabaci]", "id" : "XP_018909593.1" } ] },{ "sequence" : "MKVGTSLLLAALSVAARSVAGAGISSTTAFPTTVTIGGRAGGGGATTPGGGGTTPERAARSLFDLDATLRQWVDSPVPEQELKAVREQMARTKRNGDDFLTSALTSKSGFLESLKTAYGDIQAPSTYPEPEKKSFNLLGFKKAIFGTLLQAVKAITGGVIALKGQLIKVTGHIAATKGKVLATKGDVISELGRHIASKALAQPFYHYEGLGGGHTGYSAPSAPSYGYHGYGSYHSSYPTAPVYGPPHHSSHSSYPSGPSSYYTDYHRLSRQSKPGYPAPNVPGAPAPAGAPQPHAGQLPPGVQAGLLVLKPVQVPLGHNGHTQGPPLLPNKAATLPPSTYSSVQPSGFSHPPPPVNVNVNPQQSPYSVAPQLFHNPVQPRYPPSSGAYQVNPSPESFENYDQQESRFQYPSQPNQNGYHEATKRSPIKRLFEVPTGPGYDFAS", "md5" : "14d7f4ccd5fa00150b4ce81e302c08bb", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 278, "end" : 294, "location-fragments" : [ { "start" : 278, "end" : 294, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 249, "end" : 267, "location-fragments" : [ { "start" : 249, "end" : 267, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 378, "end" : 443, "location-fragments" : [ { "start" : 378, "end" : 443, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 317, "end" : 353, "location-fragments" : [ { "start" : 317, "end" : 353, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 248, "end" : 297, "location-fragments" : [ { "start" : 248, "end" : 297, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 382, "end" : 421, "location-fragments" : [ { "start" : 382, "end" : 421, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909695.1 PREDICTED: uncharacterized protein LOC109038890 isoform X3 [Bemisia tabaci]", "id" : "XP_018909695.1" } ] },{ "sequence" : "MQWISIPSTSESNSPNYQSQGLLNPHSGNHGGSASYSFTTDFRQSNQNTVEQGFSIYTNPLGSGCGSNRAGSCADGAEGGSGHREEKGATPSYRPLSPISPLSPSNLSSSMPNHLKSVSNYCITISPHNTMSPTLEAPTSPSSNMRKQHGHEQEDELGVKRGQHEHTHMEQGLQLSSIHHDCSNNESGGDRPNLCRICGKTYARPSTLKTHLRTHSGEKPYRCEDCNKSFSQAANLTAHVRTHSGEKPFKCNICDRRFSQSSSVTTHMRTHSGERPYRCRLCRKAFSDSSTLTKHLRIHSGEKPYQCKLCLLRFSQSGNLNRHMRVHGQHYAIPM", "md5" : "b483f82712fb146a3c181ef4a9e84d14", "matches" : [ { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 191, "end" : 243, "hmmLength" : 53, "location-fragments" : [ { "start" : 191, "end" : 243, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.33E-17, "model-ac" : "0052279" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 76, "end" : 111, "location-fragments" : [ { "start" : 76, "end" : 111, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 147, "end" : 168, "location-fragments" : [ { "start" : 147, "end" : 168, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 195, "end" : 215, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CriCgktYarpstlktHlrtH", "location-fragments" : [ { "start" : 195, "end" : 215, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 307, "end" : 327, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CklCllrFsqsgnlnrHmrvH", "location-fragments" : [ { "start" : 307, "end" : 327, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 305, "end" : 332, "score" : 11.24, "alignment" : "YQCKLCLLRFSQSGNLNRHMRVHGQHYA", "location-fragments" : [ { "start" : 305, "end" : 332, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PTHR23226", "name" : "ZINC FINGER PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 188, "end" : 258, "hmmStart" : 292, "hmmEnd" : 362, "hmmLength" : 384, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 158, "envelopeEnd" : 258, "location-fragments" : [ { "start" : 188, "end" : 258, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-89, "familyName" : "", "score" : 303.8, "model-ac" : "PTHR23226" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 272, "end" : 299, "hmmStart" : 4, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-15, "score" : 58.6, "envelopeStart" : 267, "envelopeEnd" : 302, "postProcessed" : true, "location-fragments" : [ { "start" : 272, "end" : 299, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-61, "score" : 206.2, "model-ac" : "2m9aA01" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 249, "end" : 276, "score" : 16.29, "alignment" : "FKCNICDRRFSQSSSVTTHMRTHSGERP", "location-fragments" : [ { "start" : 249, "end" : 276, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PTHR23226:SF234", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 188, "end" : 286, "hmmStart" : 264, "hmmEnd" : 362, "hmmLength" : 384, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 183, "envelopeEnd" : 286, "location-fragments" : [ { "start" : 188, "end" : 286, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-89, "familyName" : "", "score" : 303.8, "model-ac" : "PTHR23226:SF234" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 221, "end" : 248, "score" : 17.371, "alignment" : "YRCEDCNKSFSQAANLTAHVRTHSGEKP", "location-fragments" : [ { "start" : 221, "end" : 248, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 223, "end" : 243, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CedCnksFsqaanltaHvrtH", "location-fragments" : [ { "start" : 223, "end" : 243, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PTHR23226:SF234", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 209, "end" : 328, "hmmStart" : 229, "hmmEnd" : 348, "hmmLength" : 384, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 208, "envelopeEnd" : 332, "location-fragments" : [ { "start" : 209, "end" : 328, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-89, "familyName" : "", "score" : 303.8, "model-ac" : "PTHR23226:SF234" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 271, "end" : 323, "hmmLength" : 53, "location-fragments" : [ { "start" : 271, "end" : 323, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.51E-18, "model-ac" : "0053891" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 229, "end" : 286, "hmmLength" : 61, "location-fragments" : [ { "start" : 229, "end" : 286, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.85E-22, "model-ac" : "0050784" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 44, "location-fragments" : [ { "start" : 1, "end" : 44, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 193, "end" : 220, "score" : 14.981, "alignment" : "NLCRICGKTYARPSTLKTHLRTHSGEKP", "location-fragments" : [ { "start" : 193, "end" : 220, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PTHR23226", "name" : "ZINC FINGER PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 188, "end" : 286, "hmmStart" : 264, "hmmEnd" : 362, "hmmLength" : 384, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 183, "envelopeEnd" : 286, "location-fragments" : [ { "start" : 188, "end" : 286, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-89, "familyName" : "", "score" : 303.8, "model-ac" : "PTHR23226" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 194, "end" : 219, "hmmStart" : 5, "hmmEnd" : 33, "hmmLength" : 38, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.8E-12, "score" : 48.9, "envelopeStart" : 194, "envelopeEnd" : 224, "postProcessed" : true, "location-fragments" : [ { "start" : 194, "end" : 219, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-54, "score" : 183.8, "model-ac" : "2eprA01" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 251, "end" : 271, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CniCdrrFsqsssvttHmrtH", "location-fragments" : [ { "start" : 251, "end" : 271, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 129, "end" : 146, "location-fragments" : [ { "start" : 129, "end" : 146, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00096", "name" : "zf-C2H2", "description" : "Zinc finger, C2H2 type", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 277, "end" : 299, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 3.3E-5, "score" : 24.1, "envelopeStart" : 277, "envelopeEnd" : 299, "postProcessed" : true, "location-fragments" : [ { "start" : 277, "end" : 299, "dc-status" : "CONTINUOUS" } ] }, { "start" : 221, "end" : 243, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-7, "score" : 30.6, "envelopeStart" : 221, "envelopeEnd" : 243, "postProcessed" : true, "location-fragments" : [ { "start" : 221, "end" : 243, "dc-status" : "CONTINUOUS" } ] }, { "start" : 249, "end" : 271, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 5.7E-6, "score" : 26.5, "envelopeStart" : 249, "envelopeEnd" : 271, "postProcessed" : true, "location-fragments" : [ { "start" : 249, "end" : 271, "dc-status" : "CONTINUOUS" } ] }, { "start" : 305, "end" : 327, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 6.1E-5, "score" : 23.3, "envelopeStart" : 305, "envelopeEnd" : 327, "postProcessed" : true, "location-fragments" : [ { "start" : 305, "end" : 327, "dc-status" : "CONTINUOUS" } ] }, { "start" : 195, "end" : 215, "hmmStart" : 3, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.6E-5, "score" : 24.4, "envelopeStart" : 194, "envelopeEnd" : 215, "postProcessed" : true, "location-fragments" : [ { "start" : 195, "end" : 215, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-32, "score" : 108.9, "model-ac" : "PF00096" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 300, "end" : 331, "hmmStart" : 17, "hmmEnd" : 47, "hmmLength" : 54, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 8.1E-13, "score" : 49.9, "envelopeStart" : 297, "envelopeEnd" : 331, "postProcessed" : true, "location-fragments" : [ { "start" : 300, "end" : 331, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-54, "score" : 183.8, "model-ac" : "1yuiA00" }, { "signature" : { "accession" : "PTHR23226", "name" : "ZINC FINGER PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 209, "end" : 328, "hmmStart" : 229, "hmmEnd" : 348, "hmmLength" : 384, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 208, "envelopeEnd" : 332, "location-fragments" : [ { "start" : 209, "end" : 328, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-89, "familyName" : "", "score" : 303.8, "model-ac" : "PTHR23226" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 277, "end" : 304, "score" : 16.997, "alignment" : "YRCRLCRKAFSDSSTLTKHLRIHSGEKP", "location-fragments" : [ { "start" : 277, "end" : 304, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "SM00355", "name" : "c2h2final6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 193, "end" : 215, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.052, "score" : 22.7, "location-fragments" : [ { "start" : 193, "end" : 215, "dc-status" : "CONTINUOUS" } ] }, { "start" : 277, "end" : 299, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 8.6E-4, "score" : 28.6, "location-fragments" : [ { "start" : 277, "end" : 299, "dc-status" : "CONTINUOUS" } ] }, { "start" : 221, "end" : 243, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-4, "score" : 31.1, "location-fragments" : [ { "start" : 221, "end" : 243, "dc-status" : "CONTINUOUS" } ] }, { "start" : 305, "end" : 327, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 3.9E-4, "score" : 29.8, "location-fragments" : [ { "start" : 305, "end" : 327, "dc-status" : "CONTINUOUS" } ] }, { "start" : 249, "end" : 271, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 3.4E-4, "score" : 30.0, "location-fragments" : [ { "start" : 249, "end" : 271, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-38, "score" : 142.1, "model-ac" : "SM00355" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 129, "end" : 172, "location-fragments" : [ { "start" : 129, "end" : 172, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 246, "end" : 271, "hmmStart" : 7, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 3.6E-16, "score" : 60.7, "envelopeStart" : 243, "envelopeEnd" : 276, "postProcessed" : true, "location-fragments" : [ { "start" : 246, "end" : 271, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-63, "score" : 212.1, "model-ac" : "2emyA00" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 279, "end" : 299, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CrlCrkaFsdsstltkHlriH", "location-fragments" : [ { "start" : 279, "end" : 299, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 220, "end" : 245, "hmmStart" : 7, "hmmEnd" : 40, "hmmLength" : 46, "hmmBounds" : "INCOMPLETE", "evalue" : 3.3E-16, "score" : 60.8, "envelopeStart" : 215, "envelopeEnd" : 248, "postProcessed" : true, "location-fragments" : [ { "start" : 220, "end" : 245, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-63, "score" : 212.4, "model-ac" : "2el6A00" }, { "signature" : { "accession" : "PTHR23226:SF234", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 188, "end" : 258, "hmmStart" : 292, "hmmEnd" : 362, "hmmLength" : 384, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 158, "envelopeEnd" : 258, "location-fragments" : [ { "start" : 188, "end" : 258, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-89, "familyName" : "", "score" : 303.8, "model-ac" : "PTHR23226:SF234" } ], "xref" : [ { "name" : "XP_018910562.1 PREDICTED: protein glass-like [Bemisia tabaci]", "id" : "XP_018910562.1" } ] },{ "sequence" : "MVSLFGVTMKSVWFKAPVLLCFAFVHNVMPEETGSEKKSVEEEWASHNDRDHNGPSTYEFGYDLEDRKTFNIQHRKEERHPNGTVTGSYGLLEPDGSIRMVHYIADEHGYRALVEKADNNSTKSIDAAGIEDKLEPIKHLSDEDLIHIPKSPLLISAIDSLNQAASSLHEIHARPSSHPYHGRNASDFYIFIPDKILVRREVDGKTVTEEIHTGMDTTRSIAKRSVESSASSSSSSYARGKIDLPPNSPLHKKDLEFLLDQDDPHFRRKRQLTGTNGQYVTVQQEGNGAPPQTLTYNNQQNAPPPPQQEGFYEKIAPKIQDFTQNLASQWANYASNQQPLQPVLNSLPQPSGQPYVLNVPADYTKQTYRYPLNEPPPQGGPQGVPQGIPQVVPQGEYAAPQNQQFQAAPPVNGQYNQPYVPPQVNYQLNNQPYNLVPNQQYPTQYPAAPMNIEINGAPAGPDPQYNQYPPPEAPEEEQYQNNNQQVVLPQGYGQYNGPPIQTNQAVTEPTFNIPPSIPTSYTGPVNIPDMPPTGNPIIPPAAYPTATPNTPPMNYNNLNGPINEHLNSIDSPGVNQLSVQHFNHPYGVNIAPYVKVVPQEVDPNQYNLFNRPTGKQTGPSSPRPLPTDSEYYTNYYGDPYDPLDTNALKKQRMYVEPDVNRHTPGYQGGRRPYDIVQTGQSRYLPPGNLPPGPIPYASAPVPADSGQQPSSPAPTVVSSPSPPPPSPSPSLPPPSPSSEPKTRIIYYDDKIKA", "md5" : "591b874af5c3b2b606fcd7284b7884cd", "matches" : [ { "signature" : { "accession" : "PS00233", "name" : "CHIT_BIND_RR_1", "description" : "Chitin-binding type R&R domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR031311", "name" : "CHIT_BIND_RR_consensus", "description" : "Chitin-binding type R&R consensus", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 87, "end" : 112, "level" : "STRONG", "cigarAlignment" : "1M7I2M6I1M1I2M2I2M1I1M", "alignment" : "GsygllepDGsirmvhYiADehGYrA", "location-fragments" : [ { "start" : 87, "end" : 112, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00233" }, { "signature" : { "accession" : "PR00947", "name" : "CUTICLE", "description" : "Insect cuticle protein signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000618", "name" : "Insect_cuticle", "description" : "Insect cuticle protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of cuticle", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0042302" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 56, "end" : 67, "pvalue" : 0.00381, "score" : 25.14, "motifNumber" : 1, "location-fragments" : [ { "start" : 56, "end" : 67, "dc-status" : "CONTINUOUS" } ] }, { "start" : 85, "end" : 96, "pvalue" : 2.54E-5, "score" : 48.63, "motifNumber" : 2, "location-fragments" : [ { "start" : 85, "end" : 96, "dc-status" : "CONTINUOUS" } ] }, { "start" : 96, "end" : 107, "pvalue" : 9.7E-5, "score" : 49.45, "motifNumber" : 3, "location-fragments" : [ { "start" : 96, "end" : 107, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-5, "graphscan" : "iII", "model-ac" : "PR00947" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 715, "end" : 739, "location-fragments" : [ { "start" : 715, "end" : 739, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 605, "end" : 628, "location-fragments" : [ { "start" : 605, "end" : 628, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 283, "end" : 306, "location-fragments" : [ { "start" : 283, "end" : 306, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR10380:SF186", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 318, "hmmStart" : 11, "hmmEnd" : 155, "hmmLength" : 166, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 736, "location-fragments" : [ { "start" : 25, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-19, "familyName" : "", "score" : 74.4, "model-ac" : "PTHR10380:SF186" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 452, "end" : 477, "location-fragments" : [ { "start" : 452, "end" : 477, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00379", "name" : "Chitin_bind_4", "description" : "Insect cuticle protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000618", "name" : "Insect_cuticle", "description" : "Insect cuticle protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of cuticle", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0042302" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 58, "end" : 110, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 4.9E-13, "score" : 49.4, "envelopeStart" : 58, "envelopeEnd" : 110, "postProcessed" : true, "location-fragments" : [ { "start" : 58, "end" : 110, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-13, "score" : 50.1, "model-ac" : "PF00379" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 346, "end" : 426, "location-fragments" : [ { "start" : 346, "end" : 426, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 283, "end" : 308, "location-fragments" : [ { "start" : 283, "end" : 308, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 396, "end" : 426, "location-fragments" : [ { "start" : 396, "end" : 426, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 605, "end" : 630, "location-fragments" : [ { "start" : 605, "end" : 630, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51155", "name" : "CHIT_BIND_RR_2", "description" : "Chitin-binding type R&R domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000618", "name" : "Insect_cuticle", "description" : "Insect cuticle protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of cuticle", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0042302" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 55, "end" : 124, "score" : 15.763, "alignment" : "PSTYEFGYDLEDRKTFNIQHRKEERHPNGTVTGSYGLLEPDGSIRMVHYIADEHGYRALVEkaDNNSTKS", "location-fragments" : [ { "start" : 55, "end" : 124, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51155" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 648, "end" : 753, "location-fragments" : [ { "start" : 648, "end" : 753, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 213, "end" : 246, "location-fragments" : [ { "start" : 213, "end" : 246, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR10380", "name" : "CUTICLE PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 318, "hmmStart" : 11, "hmmEnd" : 155, "hmmLength" : 166, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 736, "location-fragments" : [ { "start" : 25, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-19, "familyName" : "", "score" : 74.4, "model-ac" : "PTHR10380" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 213, "end" : 241, "location-fragments" : [ { "start" : 213, "end" : 241, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910317.1 PREDICTED: extensin-2-like [Bemisia tabaci]", "id" : "XP_018910317.1" } ] },{ "sequence" : "MSLSEDPLKLVPWVRMDELVALLLNDIPTSLNEYFYWVAVHSFTADTQVLTDALTTTRRIDWHSPKLAICFNGSPEELRPFIDECRARYALDVVFDDHLPEKQWKTLDQLSSCSYTCPLDVRLAPLGTESVGLVQETWVAKYPGTDEHIARFVTHNPSLGVYDIATGELRAWILCNECSEVALLYVTDDHRRKGYAQLLVNALSDQLLRAGIIAQARIRVVNKPSLKLFKTLGFNSSTDTWFVVVGKKYNEAAGQ", "md5" : "904b21b65d7ef8f7a0243a5889ec4745", "matches" : [ { "signature" : { "accession" : "G3DSA:3.40.630.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 109, "end" : 234, "hmmStart" : 11, "hmmEnd" : 130, "hmmLength" : 131, "hmmBounds" : "COMPLETE", "evalue" : 7.1E-27, "score" : 96.0, "envelopeStart" : 109, "envelopeEnd" : 234, "postProcessed" : true, "location-fragments" : [ { "start" : 109, "end" : 234, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-27, "score" : 96.7, "model-ac" : "1sqhA02" }, { "signature" : { "accession" : "SSF55729", "name" : "Acyl-CoA N-acyltransferases (Nat)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016181", "name" : "Acyl_CoA_acyltransferase", "description" : "Acyl-CoA N-acyltransferase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 235, "hmmLength" : 297, "location-fragments" : [ { "start" : 32, "end" : 235, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.13E-26, "model-ac" : "0043712" }, { "signature" : { "accession" : "PTHR20958", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 53, "end" : 249, "hmmStart" : 111, "hmmEnd" : 306, "hmmLength" : 310, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 44, "envelopeEnd" : 253, "location-fragments" : [ { "start" : 53, "end" : 249, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-26, "familyName" : "UNCHARACTERIZED", "score" : 94.3, "model-ac" : "PTHR20958" }, { "signature" : { "accession" : "cd04301", "name" : "NAT_SF", "description" : "NAT_SF", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 164, "end" : 212, "sites" : [ { "description" : "Coenzyme A binding pocket", "numLocations" : 5, "siteLocations" : [ { "start" : 184, "end" : 184, "residue" : "L" }, { "start" : 186, "end" : 186, "residue" : "V" }, { "start" : 196, "end" : 196, "residue" : "A" }, { "start" : 185, "end" : 185, "residue" : "Y" }, { "start" : 197, "end" : 197, "residue" : "Q" } ] } ], "evalue" : 2.36087E-4, "score" : 36.4849, "location-fragments" : [ { "start" : 164, "end" : 212, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd04301" }, { "signature" : { "accession" : "PF08445", "name" : "FR47", "description" : "FR47-like protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013653", "name" : "FR47", "description" : "FR47-like", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transferase activity, transferring acyl groups other than amino-acyl groups", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016747" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 158, "end" : 242, "hmmStart" : 1, "hmmEnd" : 85, "hmmLength" : 86, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.5E-18, "score" : 65.8, "envelopeStart" : 158, "envelopeEnd" : 243, "postProcessed" : true, "location-fragments" : [ { "start" : 158, "end" : 242, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-18, "score" : 66.4, "model-ac" : "PF08445" }, { "signature" : { "accession" : "PS51186", "name" : "GNAT", "description" : "Gcn5-related N-acetyltransferase (GNAT) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000182", "name" : "GNAT_dom", "description" : "GNAT domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "N-acetyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008080" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 121, "end" : 251, "score" : 10.842, "alignment" : "VRLAPLGTESVGLVQETWVAKYPG-TDEHIARFVTHNPSLGVYDIATGELRAWILCNECS---EVALLYVTDDHRRKGYAQLLVNALSDQLLRAGI-IAQARIRVVNKPSLKLFKTLGFNS--STDTWFV--VVGKKYNE", "location-fragments" : [ { "start" : 121, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51186" } ], "xref" : [ { "name" : "XP_018909642.1 PREDICTED: uncharacterized protein LOC109038867 [Bemisia tabaci]", "id" : "XP_018909642.1" } ] },{ "sequence" : "MEQLDKLLQAAILFFVILSTINIEALYTYGAASDIFGEGKSDKEILDNLLLATRYDKRLLPPVVGTLTVNMSVLLLSLASPDESSLKYEVEFLLQQQWYDPRLTYSNQSKYDFLNAIHHHSDIWLPDTYFIMHGDFKDPLIPVHFALRIYRNGTVNYLMRRHLILSCQGRLHIFPFDDPLCSFAMESISYEQSAITYVWKNDEDTLRKSPSLTTLNAYLIQNQTIACPTKASWRDLGEAFESGSGGSPRDCKCSLCQRRFEEQGNYSCLKVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVAQGERKSDGPNDIVACTNCGPNTCTHTANNGCASEARRKEPPHPIRVAKTIDVIARITFPVAYSIFLIFFFIHYKGFQNNAEGIIIDSEPDAQPLKMPQPENTASTHQSNFDHQTTSHLSPFSSDTTPH", "md5" : "b60c5cf3dd51cd4afd2c6b1ec9f5ebb3", "matches" : [ { "signature" : { "accession" : "SSF63712", "name" : "Nicotinic receptor ligand binding domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036734", "name" : "Neur_chan_lig-bd_sf", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 230, "hmmLength" : 205, "location-fragments" : [ { "start" : 42, "end" : 230, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.57E-35, "model-ac" : "0038932" }, { "signature" : { "accession" : "PTHR18945:SF819", "name" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 70, "end" : 377, "hmmStart" : 110, "hmmEnd" : 388, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 64, "envelopeEnd" : 388, "location-fragments" : [ { "start" : 70, "end" : 377, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-162, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 542.6, "model-ac" : "PTHR18945:SF819" }, { "signature" : { "accession" : "PF02932", "name" : "Neur_chan_memb", "description" : "Neurotransmitter-gated ion-channel transmembrane region", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006029", "name" : "Neurotrans-gated_channel_TM", "description" : "Neurotransmitter-gated ion-channel transmembrane domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 287, "end" : 373, "hmmStart" : 2, "hmmEnd" : 88, "hmmLength" : 238, "hmmBounds" : "INCOMPLETE", "evalue" : 1.5E-12, "score" : 48.1, "envelopeStart" : 286, "envelopeEnd" : 384, "postProcessed" : true, "location-fragments" : [ { "start" : 287, "end" : 373, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-15, "score" : 56.4, "model-ac" : "PF02932" }, { "signature" : { "accession" : "PTHR18945", "name" : "NEUROTRANSMITTER GATED ION CHANNEL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 386, "end" : 456, "hmmStart" : 416, "hmmEnd" : 494, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 374, "envelopeEnd" : 462, "location-fragments" : [ { "start" : 386, "end" : 456, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-162, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 542.6, "model-ac" : "PTHR18945" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 482, "end" : 513, "location-fragments" : [ { "start" : 482, "end" : 513, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 473, "end" : 513, "location-fragments" : [ { "start" : 473, "end" : 513, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd19049", "name" : "LGIC_TM_anion", "description" : "LGIC_TM_anion", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 281, "end" : 455, "sites" : [ { "description" : "pentamer interface", "numLocations" : 35, "siteLocations" : [ { "start" : 303, "end" : 303, "residue" : "L" }, { "start" : 357, "end" : 357, "residue" : "L" }, { "start" : 293, "end" : 293, "residue" : "L" }, { "start" : 284, "end" : 284, "residue" : "T" }, { "start" : 310, "end" : 310, "residue" : "A" }, { "start" : 299, "end" : 299, "residue" : "I" }, { "start" : 330, "end" : 330, "residue" : "R" }, { "start" : 296, "end" : 296, "residue" : "S" }, { "start" : 331, "end" : 331, "residue" : "S" }, { "start" : 440, "end" : 440, "residue" : "R" }, { "start" : 292, "end" : 292, "residue" : "I" }, { "start" : 314, "end" : 314, "residue" : "I" }, { "start" : 295, "end" : 295, "residue" : "T" }, { "start" : 328, "end" : 328, "residue" : "G" }, { "start" : 313, "end" : 313, "residue" : "M" }, { "start" : 321, "end" : 321, "residue" : "N" }, { "start" : 285, "end" : 285, "residue" : "T" }, { "start" : 312, "end" : 312, "residue" : "V" }, { "start" : 317, "end" : 317, "residue" : "T" }, { "start" : 364, "end" : 364, "residue" : "N" }, { "start" : 281, "end" : 281, "residue" : "F" }, { "start" : 309, "end" : 309, "residue" : "P" }, { "start" : 320, "end" : 320, "residue" : "L" }, { "start" : 316, "end" : 316, "residue" : "V" }, { "start" : 339, "end" : 339, "residue" : "L" }, { "start" : 302, "end" : 302, "residue" : "W" }, { "start" : 304, "end" : 304, "residue" : "E" }, { "start" : 307, "end" : 307, "residue" : "A" }, { "start" : 338, "end" : 338, "residue" : "N" }, { "start" : 361, "end" : 361, "residue" : "V" }, { "start" : 354, "end" : 354, "residue" : "Y" }, { "start" : 308, "end" : 308, "residue" : "V" }, { "start" : 365, "end" : 365, "residue" : "Y" }, { "start" : 350, "end" : 350, "residue" : "M" }, { "start" : 327, "end" : 327, "residue" : "N" } ] } ], "evalue" : 3.3554E-32, "score" : 117.168, "location-fragments" : [ { "start" : 281, "end" : 455, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd19049" }, { "signature" : { "accession" : "PR00253", "name" : "GABAARECEPTR", "description" : "Gamma-aminobutyric acid A (GABAA) receptor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR006028", "name" : "GABAA/Glycine_rcpt", "description" : "Gamma-aminobutyric acid A receptor/Glycine receptor alpha", "type" : "FAMILY", "goXRefs" : [ { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 342, "end" : 363, "pvalue" : 1.38E-8, "score" : 35.36, "motifNumber" : 3, "location-fragments" : [ { "start" : 342, "end" : 363, "dc-status" : "CONTINUOUS" } ] }, { "start" : 308, "end" : 329, "pvalue" : 5.95E-10, "score" : 43.64, "motifNumber" : 2, "location-fragments" : [ { "start" : 308, "end" : 329, "dc-status" : "CONTINUOUS" } ] }, { "start" : 282, "end" : 302, "pvalue" : 1.07E-5, "score" : 29.84, "motifNumber" : 1, "location-fragments" : [ { "start" : 282, "end" : 302, "dc-status" : "CONTINUOUS" } ] }, { "start" : 438, "end" : 458, "pvalue" : 2.93E-6, "score" : 34.22, "motifNumber" : 4, "location-fragments" : [ { "start" : 438, "end" : 458, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-22, "graphscan" : "iIII", "model-ac" : "PR00253" }, { "signature" : { "accession" : "cd18987", "name" : "LGIC_ECD_anion", "description" : "LGIC_ECD_anion", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 67, "end" : 278, "sites" : [ { "description" : "pentamer interface", "numLocations" : 30, "siteLocations" : [ { "start" : 160, "end" : 160, "residue" : "R" }, { "start" : 148, "end" : 148, "residue" : "R" }, { "start" : 134, "end" : 134, "residue" : "G" }, { "start" : 136, "end" : 136, "residue" : "F" }, { "start" : 93, "end" : 93, "residue" : "L" }, { "start" : 126, "end" : 126, "residue" : "P" }, { "start" : 144, "end" : 144, "residue" : "H" }, { "start" : 131, "end" : 131, "residue" : "I" }, { "start" : 85, "end" : 85, "residue" : "S" }, { "start" : 188, "end" : 188, "residue" : "I" }, { "start" : 139, "end" : 139, "residue" : "P" }, { "start" : 158, "end" : 158, "residue" : "L" }, { "start" : 79, "end" : 79, "residue" : "A" }, { "start" : 130, "end" : 130, "residue" : "F" }, { "start" : 77, "end" : 77, "residue" : "S" }, { "start" : 128, "end" : 128, "residue" : "T" }, { "start" : 96, "end" : 96, "residue" : "Q" }, { "start" : 145, "end" : 145, "residue" : "F" }, { "start" : 278, "end" : 278, "residue" : "D" }, { "start" : 115, "end" : 115, "residue" : "N" }, { "start" : 117, "end" : 117, "residue" : "I" }, { "start" : 86, "end" : 86, "residue" : "L" }, { "start" : 138, "end" : 138, "residue" : "D" }, { "start" : 95, "end" : 95, "residue" : "Q" }, { "start" : 127, "end" : 127, "residue" : "D" }, { "start" : 118, "end" : 118, "residue" : "H" }, { "start" : 159, "end" : 159, "residue" : "M" }, { "start" : 80, "end" : 80, "residue" : "S" }, { "start" : 129, "end" : 129, "residue" : "Y" }, { "start" : 146, "end" : 146, "residue" : "A" } ] } ], "evalue" : 3.84145E-43, "score" : 149.366, "location-fragments" : [ { "start" : 67, "end" : 278, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18987" }, { "signature" : { "accession" : "PTHR18945:SF819", "name" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 386, "end" : 456, "hmmStart" : 416, "hmmEnd" : 494, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 374, "envelopeEnd" : 462, "location-fragments" : [ { "start" : 386, "end" : 456, "dc-status" : "CONTINUOUS" } ] }, { "start" : 23, "end" : 63, "hmmStart" : 38, "hmmEnd" : 78, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 67, "location-fragments" : [ { "start" : 23, "end" : 63, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-162, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 542.6, "model-ac" : "PTHR18945:SF819" }, { "signature" : { "accession" : "SSF90112", "name" : "Neurotransmitter-gated ion-channel transmembrane pore", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036719", "name" : "Neuro-gated_channel_TM_sf", "description" : "Neurotransmitter-gated ion-channel transmembrane domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 281, "end" : 459, "hmmLength" : 227, "location-fragments" : [ { "start" : 281, "end" : 459, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.66E-28, "model-ac" : "0041810" }, { "signature" : { "accession" : "PF02931", "name" : "Neur_chan_LBD", "description" : "Neurotransmitter-gated ion-channel ligand binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006202", "name" : "Neur_chan_lig-bd", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 210, "hmmStart" : 3, "hmmEnd" : 169, "hmmLength" : 217, "hmmBounds" : "INCOMPLETE", "evalue" : 8.4E-31, "score" : 107.1, "envelopeStart" : 42, "envelopeEnd" : 233, "postProcessed" : true, "location-fragments" : [ { "start" : 44, "end" : 210, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-31, "score" : 107.7, "model-ac" : "PF02931" }, { "signature" : { "accession" : "PTHR18945", "name" : "NEUROTRANSMITTER GATED ION CHANNEL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 70, "end" : 377, "hmmStart" : 110, "hmmEnd" : 388, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 64, "envelopeEnd" : 388, "location-fragments" : [ { "start" : 70, "end" : 377, "dc-status" : "CONTINUOUS" } ] }, { "start" : 23, "end" : 63, "hmmStart" : 38, "hmmEnd" : 78, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 67, "location-fragments" : [ { "start" : 23, "end" : 63, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-162, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 542.6, "model-ac" : "PTHR18945" } ], "xref" : [ { "name" : "XP_018910293.1 PREDICTED: glutamate-gated chloride channel isoform X2 [Bemisia tabaci]", "id" : "XP_018910293.1" } ] },{ "sequence" : "MNHSEAQSYAIPVAGLRFESLCLKNAQFLMRNGGDAPNIGHLRCHILAASVYVCLCLGDSILALNHANSLLCQNSLSGAHKFLGHLYAAEALIILGQSSEAMDYLKLDYLNDLSLLSPPQKYEVPLKPPISWFPNNITVAKNILQFNLAVALVIQEESEKSAEVLKSVQCQSSW", "md5" : "06bc10b5c3622f7819dce3e76ca723b8", "matches" : [ { "signature" : { "accession" : "PTHR12979", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR039740", "name" : "CNOT10", "description" : "CCR4-NOT transcription complex subunit 10", "type" : "FAMILY", "goXRefs" : [ { "name" : "CCR4-NOT complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0030014" } ], "pathwayXRefs" : [ { "name" : "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "databaseName" : "Reactome", "id" : "R-HSA-6804115" }, { "name" : "Deadenylation of mRNA", "databaseName" : "Reactome", "id" : "R-HSA-429947" } ] } }, "locations" : [ { "start" : 3, "end" : 166, "hmmStart" : 456, "hmmEnd" : 645, "hmmLength" : 692, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 172, "location-fragments" : [ { "start" : 3, "end" : 166, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-33, "familyName" : "FAMILY NOT NAMED", "score" : 117.3, "model-ac" : "PTHR12979" } ], "xref" : [ { "name" : "XP_018910435.1 PREDICTED: CCR4-NOT transcription complex subunit 10-like [Bemisia tabaci]", "id" : "XP_018910435.1" }, { "name" : "XP_018910432.1 PREDICTED: CCR4-NOT transcription complex subunit 10-like [Bemisia tabaci]", "id" : "XP_018910432.1" }, { "name" : "XP_018910433.1 PREDICTED: CCR4-NOT transcription complex subunit 10-like [Bemisia tabaci]", "id" : "XP_018910433.1" } ] },{ "sequence" : "MCTPIVSHLNMEQLLTCPYEPAHRIRRFKMCLHINKCRRNYEKNNPEQEMKTCIYNFNHVVPEMEWEYHMEECDDRIKGDRVRYQIETDPEPAVENTNQIPVSDIPHVECDDDWNLPTTVGSVNANIQASLKERKVIIPRQGATKSERKAHYMEERKRHNVFDDVNKPSTSFASAPIDNNQPLRKPRTTSVLSDFPSTASSSTQQAPPSPKAKQTEKSKTAVNAPPQAFPKGRGRAPGDNVVSAPKPEPKVGCRLPGTSKAVNPAPTPNINGVSQNMANLNIDPLKFGGIDEDGFISIPIPNKGRGRKLNPSA", "md5" : "0bc3587487cc3048a69169c05c62831d", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 165, "end" : 222, "location-fragments" : [ { "start" : 165, "end" : 222, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51800", "name" : "ZF_CHHC_U11_48K", "description" : "Zinc finger CHHC U11-48K-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR022776", "name" : "TRM13/UPF0224_CHHC_Znf_dom", "description" : "TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 41, "score" : 13.31, "alignment" : "LLTCPYEPAHRIRRFKMCLHINKCRRNY", "location-fragments" : [ { "start" : 14, "end" : 41, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51800" }, { "signature" : { "accession" : "PS51800", "name" : "ZF_CHHC_U11_48K", "description" : "Zinc finger CHHC U11-48K-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR022776", "name" : "TRM13/UPF0224_CHHC_Znf_dom", "description" : "TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 77, "score" : 12.522, "alignment" : "MKTCIYNFNHVVPEMEWEYHMEECDDRI", "location-fragments" : [ { "start" : 50, "end" : 77, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51800" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 43, "hmmLength" : 35, "location-fragments" : [ { "start" : 13, "end" : 43, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.28E-6, "model-ac" : "0054735" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 140, "end" : 164, "location-fragments" : [ { "start" : 140, "end" : 164, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR21402", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 116, "hmmStart" : 11, "hmmEnd" : 113, "hmmLength" : 166, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 236, "location-fragments" : [ { "start" : 9, "end" : 116, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-17, "familyName" : "GAMETOCYTE SPECIFIC FACTOR 1", "score" : 65.6, "model-ac" : "PTHR21402" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 140, "end" : 240, "location-fragments" : [ { "start" : 140, "end" : 240, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR21402:SF5", "name" : "GAMETOCYTE SPECIFIC FACTOR 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 116, "hmmStart" : 11, "hmmEnd" : 113, "hmmLength" : 166, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 236, "location-fragments" : [ { "start" : 9, "end" : 116, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-17, "familyName" : "GAMETOCYTE SPECIFIC FACTOR 1", "score" : 65.6, "model-ac" : "PTHR21402:SF5" } ], "xref" : [ { "name" : "XP_018909588.1 PREDICTED: protein D7-like [Bemisia tabaci]", "id" : "XP_018909588.1" } ] },{ "sequence" : "MAPLPKSRVSPSRPFSVTGVDFCGPVIIRPSKNSKARTKGYIALFVCFSTKAIHCELMSDLSTPTFIEALCRFVSRRGICKDLHSDNAKTFKGCDKALKRMFSMLPEDSKFQEFLAKHRISWHYIPPRSPTFAGLWEAAIKSCKFHLRRVFSSAVFTYAEFETVLLQVEACLNSRPLTALSNDPQDLEPLTPGHFLIGEPLTLLPLSVALKPDIDERCTLKSKFLLQQERLCNFWNRWQREYLAQLHQRAKWKCPEENLTPGTLVAIQEPRLLPSQWSIGRVETTHAGADGKVRVATIRTSKGLITRGVSRLARIP", "md5" : "593c384449340d584ff327cd45d393b2", "matches" : [ { "signature" : { "accession" : "PF00665", "name" : "rve", "description" : "Integrase core domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001584", "name" : "Integrase_cat-core", "description" : "Integrase, catalytic core", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA integration", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0015074" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 130, "hmmStart" : 3, "hmmEnd" : 102, "hmmLength" : 102, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.9E-8, "score" : 34.5, "envelopeStart" : 11, "envelopeEnd" : 130, "postProcessed" : true, "location-fragments" : [ { "start" : 13, "end" : 130, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-8, "score" : 35.4, "model-ac" : "PF00665" }, { "signature" : { "accession" : "PS50994", "name" : "INTEGRASE", "description" : "Integrase catalytic domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001584", "name" : "Integrase_cat-core", "description" : "Integrase, catalytic core", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA integration", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0015074" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 200, "score" : 13.704, "alignment" : "SPSRPFSVTGVDFCGPVIIRpsknskaRTKGYIALFVCFSTKAIHCELMSDLSTPTFIEALCRFVSRR-GICKDLHSDNAKTFkgcdkalkrmfsmlpEDSKFQEFLAKHRISWHYIPPRSPTFAGLWEAAIKSCKFHLRRVFSSAVftYAEFETVLLQVEACLNSRPLtalsndpQDLEPLTPGHFLIGEP", "location-fragments" : [ { "start" : 10, "end" : 200, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50994" }, { "signature" : { "accession" : "SSF53098", "name" : "Ribonuclease H-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR012337", "name" : "RNaseH-like_sf", "description" : "Ribonuclease H-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 186, "hmmLength" : 168, "location-fragments" : [ { "start" : 10, "end" : 186, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.61E-21, "model-ac" : "0046055" }, { "signature" : { "accession" : "PTHR22955:SF60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 293, "hmmStart" : 1176, "hmmEnd" : 1451, "hmmLength" : 1456, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 311, "location-fragments" : [ { "start" : 1, "end" : 293, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-63, "familyName" : "", "score" : 217.3, "model-ac" : "PTHR22955:SF60" }, { "signature" : { "accession" : "G3DSA:3.30.420.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036397", "name" : "RNaseH_sf", "description" : "Ribonuclease H superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 192, "hmmStart" : 8, "hmmEnd" : 158, "hmmLength" : 200, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-15, "score" : 57.5, "envelopeStart" : 6, "envelopeEnd" : 192, "postProcessed" : true, "location-fragments" : [ { "start" : 6, "end" : 192, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-15, "score" : 58.5, "model-ac" : "2x78A00" }, { "signature" : { "accession" : "PF18701", "name" : "DUF5641", "description" : "Family of unknown function (DUF5641)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR040676", "name" : "DUF5641", "description" : "Domain of unknown function DUF5641", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 225, "end" : 313, "hmmStart" : 4, "hmmEnd" : 92, "hmmLength" : 94, "hmmBounds" : "INCOMPLETE", "evalue" : 4.6E-28, "score" : 97.2, "envelopeStart" : 222, "envelopeEnd" : 315, "postProcessed" : true, "location-fragments" : [ { "start" : 225, "end" : 313, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-28, "score" : 97.8, "model-ac" : "PF18701" }, { "signature" : { "accession" : "PTHR22955", "name" : "RETROTRANSPOSON", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 293, "hmmStart" : 1176, "hmmEnd" : 1451, "hmmLength" : 1456, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 311, "location-fragments" : [ { "start" : 1, "end" : 293, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-63, "familyName" : "", "score" : 217.3, "model-ac" : "PTHR22955" } ], "xref" : [ { "name" : "XP_018910421.1 PREDICTED: uncharacterized protein LOC109039408 [Bemisia tabaci]", "id" : "XP_018910421.1" } ] },{ "sequence" : "MSVMSFAESDVGARGVTVAHDPKRAISEETENSLKNDCEKTRRYKIESNCSNKEVILDKSGYDFSDSNNVDHEPIYIKSVIFVQDKNVEQEVHSLPDFYDTNFGSNASLSSVSDSSEEIGINKGSVEPVREHGDPDTFNICKSEERPAACETQDGDFHNIQIFPAEFRSCSQREFPNAVLEFASLTRNAFPAHVA", "md5" : "6dade2f09cd6a57ebe50ac8d889915ae", "matches" : [ ], "xref" : [ { "name" : "XP_018910278.1 PREDICTED: uncharacterized protein LOC109039307 [Bemisia tabaci]", "id" : "XP_018910278.1" } ] },{ "sequence" : "MDGENVNSNGVSETDARGDKAAGAAMFPQNGRGETKTEVTSASRGCSFYKDTAETVTARMASDRDAWYYNMNHKNRGIAIIFNHENFTNPKLKTRCGTKTDCENLASTLRSLRFEVYTYFDASYSKVMSVISEVRNMDHSDNDCFLMAVLSHGEQNIIHAYDSPYQPEDLWHPFTADKCPSLAGKPKLFFIQACQGDRLDPGVTLMKRTETDSGPMSYRIPVHADFLIAYSTIPERRKVRTRLGRILAFFSCKERRRSRLRHQQCCYTLTPDEGTENMMTEDQCCQGFYSWRNTQRGSWFMQALCEELKKHCYSLDLLTILTFVNRRVATDYQSNVPGNNEMDAQKQIPCITYMLTRLLKFKPK", "md5" : "f2f4f3edf9ad4ac25d1d680b52a33caa", "matches" : [ { "signature" : { "accession" : "SM00115", "name" : "caspase_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR015917", "name" : "Pept_C14A", "description" : "Peptidase C14A, caspase catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 68, "end" : 363, "hmmStart" : 1, "hmmEnd" : 282, "hmmLength" : 282, "hmmBounds" : "COMPLETE", "evalue" : 9.6E-91, "score" : 317.4, "location-fragments" : [ { "start" : 68, "end" : 363, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.6E-91, "score" : 317.4, "model-ac" : "SM00115" }, { "signature" : { "accession" : "PTHR10454", "name" : "CASPASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR002398", "name" : "Pept_C14", "description" : "Peptidase C14 family", "type" : "FAMILY", "goXRefs" : [ { "name" : "cysteine-type endopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004197" }, { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 240, "hmmStart" : 14, "hmmEnd" : 204, "hmmLength" : 272, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 16, "envelopeEnd" : 264, "location-fragments" : [ { "start" : 50, "end" : 240, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-96, "familyName" : "AT03047P-RELATED", "score" : 324.6, "model-ac" : "PTHR10454" }, { "signature" : { "accession" : "PS50207", "name" : "CASPASE_P10", "description" : "Caspase family p10 domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002138", "name" : "Pept_C14_p10", "description" : "Peptidase C14, caspase non-catalytic subunit p10", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type endopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004197" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 284, "end" : 363, "score" : 26.57, "alignment" : "----------------CCQGFYSWRNTQRGSWFMQALCEELKKHCYSLDLLTILTFVNRRVAtdyqSNVPGNNEMDAQKQIPCITYMLTRLLKFKP", "location-fragments" : [ { "start" : 284, "end" : 363, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50207" }, { "signature" : { "accession" : "PF00656", "name" : "Peptidase_C14", "description" : "Caspase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 284, "end" : 360, "hmmStart" : 177, "hmmEnd" : 246, "hmmLength" : 247, "hmmBounds" : "INCOMPLETE", "evalue" : 1.5E-10, "score" : 41.5, "envelopeStart" : 283, "envelopeEnd" : 361, "postProcessed" : true, "location-fragments" : [ { "start" : 284, "end" : 360, "dc-status" : "CONTINUOUS" } ] }, { "start" : 77, "end" : 235, "hmmStart" : 1, "hmmEnd" : 180, "hmmLength" : 247, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.3E-26, "score" : 93.3, "envelopeStart" : 77, "envelopeEnd" : 252, "postProcessed" : true, "location-fragments" : [ { "start" : 77, "end" : 235, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-39, "score" : 136.8, "model-ac" : "PF00656" }, { "signature" : { "accession" : "SSF52129", "name" : "Caspase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029030", "name" : "Caspase-like_dom_sf", "description" : "Caspase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 60, "end" : 237, "hmmLength" : 256, "location-fragments" : [ { "start" : 60, "end" : 237, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.79E-59, "model-ac" : "0040830" }, { "signature" : { "accession" : "PS01121", "name" : "CASPASE_HIS", "description" : "Caspase family histidine active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR016129", "name" : "Caspase_his_AS", "description" : "Peptidase family C14A, His active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 139, "end" : 153, "level" : "STRONG", "cigarAlignment" : "1M4I1M2I1M1I5M", "alignment" : "HsdndCflMaVLSHG", "location-fragments" : [ { "start" : 139, "end" : 153, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01121" }, { "signature" : { "accession" : "PR00376", "name" : "IL1BCENZYME", "description" : "Interleukin-1B converting enzyme signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR015917", "name" : "Pept_C14A", "description" : "Peptidase C14A, caspase catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 95, "end" : 113, "pvalue" : 1.51E-5, "score" : 34.61, "motifNumber" : 2, "location-fragments" : [ { "start" : 95, "end" : 113, "dc-status" : "CONTINUOUS" } ] }, { "start" : 113, "end" : 131, "pvalue" : 0.0285, "score" : 17.38, "motifNumber" : 3, "location-fragments" : [ { "start" : 113, "end" : 131, "dc-status" : "CONTINUOUS" } ] }, { "start" : 145, "end" : 153, "pvalue" : 6.71E-4, "score" : 48.48, "motifNumber" : 4, "location-fragments" : [ { "start" : 145, "end" : 153, "dc-status" : "CONTINUOUS" } ] }, { "start" : 75, "end" : 88, "pvalue" : 3.6E-6, "score" : 39.83, "motifNumber" : 1, "location-fragments" : [ { "start" : 75, "end" : 88, "dc-status" : "CONTINUOUS" } ] }, { "start" : 179, "end" : 197, "pvalue" : 1.23E-11, "score" : 68.26, "motifNumber" : 5, "location-fragments" : [ { "start" : 179, "end" : 197, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-20, "graphscan" : "IIiII..", "model-ac" : "PR00376" }, { "signature" : { "accession" : "SSF52129", "name" : "Caspase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029030", "name" : "Caspase-like_dom_sf", "description" : "Caspase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 284, "end" : 363, "hmmLength" : 256, "location-fragments" : [ { "start" : 284, "end" : 363, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.14E-25, "model-ac" : "0040830" }, { "signature" : { "accession" : "PS50208", "name" : "CASPASE_P20", "description" : "Caspase family p20 domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001309", "name" : "Pept_C14_p20", "description" : "Peptidase C14, p20 domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "cysteine-type endopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004197" }, { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 75, "end" : 198, "score" : 39.066, "alignment" : "NRGIAIIFNHENFTnpKLKTRCGTKTDCENLASTLRSLRFEVYTYFDASYSKVMSVISEVRNMDHSDNDCFLMAVLSHGEQNIIHAYDS-PYQPEDLWHPFTADKCPSLAGKPKLFFIQACQGDR", "location-fragments" : [ { "start" : 75, "end" : 198, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50208" }, { "signature" : { "accession" : "PTHR10454:SF216", "name" : "AT03047P-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 50, "end" : 240, "hmmStart" : 14, "hmmEnd" : 204, "hmmLength" : 272, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 16, "envelopeEnd" : 264, "location-fragments" : [ { "start" : 50, "end" : 240, "dc-status" : "CONTINUOUS" } ] }, { "start" : 284, "end" : 363, "hmmStart" : 196, "hmmEnd" : 271, "hmmLength" : 272, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 275, "envelopeEnd" : 364, "location-fragments" : [ { "start" : 284, "end" : 363, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-96, "familyName" : "AT03047P-RELATED", "score" : 324.6, "model-ac" : "PTHR10454:SF216" }, { "signature" : { "accession" : "cd00032", "name" : "CASc", "description" : "CASc", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR015917", "name" : "Pept_C14A", "description" : "Peptidase C14A, caspase catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 68, "end" : 362, "sites" : [ { "description" : "dimer interface", "numLocations" : 15, "siteLocations" : [ { "start" : 354, "end" : 354, "residue" : "M" }, { "start" : 325, "end" : 325, "residue" : "N" }, { "start" : 223, "end" : 223, "residue" : "H" }, { "start" : 319, "end" : 319, "residue" : "T" }, { "start" : 200, "end" : 200, "residue" : "D" }, { "start" : 352, "end" : 352, "residue" : "T" }, { "start" : 357, "end" : 357, "residue" : "R" }, { "start" : 222, "end" : 222, "residue" : "V" }, { "start" : 346, "end" : 346, "residue" : "K" }, { "start" : 351, "end" : 351, "residue" : "I" }, { "start" : 311, "end" : 311, "residue" : "H" }, { "start" : 358, "end" : 358, "residue" : "L" }, { "start" : 230, "end" : 230, "residue" : "Y" }, { "start" : 233, "end" : 233, "residue" : "I" }, { "start" : 288, "end" : 288, "residue" : "F" } ] }, { "description" : "proteolytic cleavage site", "numLocations" : 2, "siteLocations" : [ { "start" : 221, "end" : 221, "residue" : "P" }, { "start" : 201, "end" : 201, "residue" : "P" } ] }, { "description" : "substrate pocket", "numLocations" : 12, "siteLocations" : [ { "start" : 192, "end" : 192, "residue" : "Q" }, { "start" : 199, "end" : 199, "residue" : "L" }, { "start" : 153, "end" : 153, "residue" : "G" }, { "start" : 293, "end" : 293, "residue" : "N" }, { "start" : 294, "end" : 294, "residue" : "T" }, { "start" : 292, "end" : 292, "residue" : "R" }, { "start" : 290, "end" : 290, "residue" : "S" }, { "start" : 298, "end" : 298, "residue" : "S" }, { "start" : 95, "end" : 95, "residue" : "R" }, { "start" : 291, "end" : 291, "residue" : "W" }, { "start" : 299, "end" : 299, "residue" : "W" }, { "start" : 289, "end" : 289, "residue" : "Y" } ] }, { "description" : "active site", "numLocations" : 2, "siteLocations" : [ { "start" : 152, "end" : 152, "residue" : "H" }, { "start" : 194, "end" : 194, "residue" : "C" } ] } ], "evalue" : 3.65679E-93, "score" : 276.404, "location-fragments" : [ { "start" : 68, "end" : 362, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00032" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 38, "location-fragments" : [ { "start" : 1, "end" : 38, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS01122", "name" : "CASPASE_CYS", "description" : "Caspase family cysteine active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR033139", "name" : "Caspase_cys_AS", "description" : "Peptidase family C14A, cysteine active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 185, "end" : 196, "level" : "STRONG", "cigarAlignment" : "12M", "alignment" : "KPKLFFIQACQG", "location-fragments" : [ { "start" : 185, "end" : 196, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01122" }, { "signature" : { "accession" : "PTHR10454", "name" : "CASPASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR002398", "name" : "Pept_C14", "description" : "Peptidase C14 family", "type" : "FAMILY", "goXRefs" : [ { "name" : "cysteine-type endopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004197" }, { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 284, "end" : 363, "hmmStart" : 196, "hmmEnd" : 271, "hmmLength" : 272, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 275, "envelopeEnd" : 364, "location-fragments" : [ { "start" : 284, "end" : 363, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-96, "familyName" : "AT03047P-RELATED", "score" : 324.6, "model-ac" : "PTHR10454" } ], "xref" : [ { "name" : "XP_018910199.1 PREDICTED: caspase-1-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910199.1" } ] },{ "sequence" : "MRASRYVLEHIVSYGLKTAQVDAETRRIVTFDEIRRKSKSLTKWLRLHGFGRGCTIGLLSRNSLDFAWILLGIWESGAVCHLIDFRYTLREVIHALETAPVDVLILQRGVFQTLACSETEQIKHIFEFGEENVPYSEAATPLDTIFKFDISVNCMAQPSEDNTSLEMENEPDPLVLILSSSGTTGLPKGVMHTEDSIFAGLELGSSNILVQNDDKTIGLLPFHHAYGLSVMLNSLCVGALMVVIPKFSLPFWIETIQTFSITRLHLVPSLLLTLLKSNTLDFRDLLSVKHVCVGGAPMFEDSIETYMDKFLQPVVIQKVYGCTECFHYLFSQVYDAKRPGSLGKVAPSLHVKIVDLKSREVLGPNSVGEICIKGRPVAKGYINNPKANACAFDADRWFLTGDMGYFDEDGYFYFVDRFKNIIKYQGNQVSPSELEFVLIAHPNIVEAAVIGIEHEIFGQVPRAYVIPRESHDNTAQEIHDYMRSVLAPFKLLRGGLVYTSYIPKTSTGKVQRHSLHNMVVQKIHFDLKMKTYDQAEVDKKLQRAVDAETHRKISFDDVKCKCANLAKWFRAHNLGKGSTVGLMSSNNIDFIWILLGVWTSGAACRLICPKSTLYELIHSLDITPVECLLMQKGKLKRLACPKISAVKYVLEFGEEKTKCSDGAIRLEDALKDFKEDDHFDQSPQVKPTVQNETQNVAARDKSSNIPDDIALILTSSGTTGLPKCVMLTHDNIIAALKKRHLFVEKSAVALGLMPFRHAYGLITMVMCLCEGAVLVNMTSFSFLRWINVIKEFSVSHLHIVPSLSLSLLKSDLVNFEDLRSVRQIWVAAAPICEEAHEKLKKKFHQPVRIYKAYGLTEATFIVAFGEFERQKPGCIGKIVETMQCKIIDKDSGDDLPINKVGEVCFKGPMVAKGYVNDPEATAEIFCSGGWVRSGDLGSLDEAGYFYYVDRMKNIIKYQGQQISPCELETVLISHSDVKEAAVIGVPHEIFGEVPRAFIVPLDHSKVIAQDIHDYMKEMVAPFKQLRGGIVFLTELPKTGLGKVKRSTLLNFEPKTVFYDEIRGKISVHSHTLESGENRTEAVTTE", "md5" : "27456ad8ebe86812404362be9697a55b", "matches" : [ { "signature" : { "accession" : "SSF56801", "name" : "Acetyl-CoA synthetase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 522, "hmmLength" : 643, "location-fragments" : [ { "start" : 7, "end" : 522, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.96E-116, "model-ac" : "0042298" }, { "signature" : { "accession" : "cd05911", "name" : "Firefly_Luc_like", "description" : "Firefly_Luc_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 511, "sites" : [ { "description" : "acyl-activating enzyme (AAE) consensus motif", "numLocations" : 9, "siteLocations" : [ { "start" : 185, "end" : 185, "residue" : "G" }, { "start" : 187, "end" : 187, "residue" : "P" }, { "start" : 180, "end" : 180, "residue" : "S" }, { "start" : 183, "end" : 183, "residue" : "T" }, { "start" : 181, "end" : 181, "residue" : "S" }, { "start" : 177, "end" : 177, "residue" : "I" }, { "start" : 182, "end" : 182, "residue" : "G" }, { "start" : 188, "end" : 188, "residue" : "K" }, { "start" : 184, "end" : 184, "residue" : "T" } ] }, { "description" : "AMP binding site", "numLocations" : 16, "siteLocations" : [ { "start" : 423, "end" : 423, "residue" : "K" }, { "start" : 414, "end" : 414, "residue" : "F" }, { "start" : 321, "end" : 321, "residue" : "G" }, { "start" : 295, "end" : 295, "residue" : "G" }, { "start" : 417, "end" : 417, "residue" : "R" }, { "start" : 402, "end" : 402, "residue" : "D" }, { "start" : 428, "end" : 428, "residue" : "Q" }, { "start" : 297, "end" : 297, "residue" : "P" }, { "start" : 323, "end" : 323, "residue" : "T" }, { "start" : 296, "end" : 296, "residue" : "A" }, { "start" : 421, "end" : 421, "residue" : "I" }, { "start" : 319, "end" : 319, "residue" : "V" }, { "start" : 224, "end" : 224, "residue" : "H" }, { "start" : 320, "end" : 320, "residue" : "Y" }, { "start" : 419, "end" : 419, "residue" : "K" }, { "start" : 322, "end" : 322, "residue" : "C" } ] } ], "evalue" : 2.30152E-136, "score" : 418.925, "location-fragments" : [ { "start" : 19, "end" : 511, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd05911" }, { "signature" : { "accession" : "SSF56801", "name" : "Acetyl-CoA synthetase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 548, "end" : 1051, "hmmLength" : 643, "location-fragments" : [ { "start" : 548, "end" : 1051, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.09E-115, "model-ac" : "0042298" }, { "signature" : { "accession" : "PF13193", "name" : "AMP-binding_C", "description" : "AMP-binding enzyme C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR025110", "name" : "AMP-bd_C", "description" : "AMP-binding enzyme, C-terminal domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 433, "end" : 509, "hmmStart" : 1, "hmmEnd" : 76, "hmmLength" : 76, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-13, "score" : 51.7, "envelopeStart" : 433, "envelopeEnd" : 509, "postProcessed" : true, "location-fragments" : [ { "start" : 433, "end" : 509, "dc-status" : "CONTINUOUS" } ] }, { "start" : 966, "end" : 1042, "hmmStart" : 1, "hmmEnd" : 76, "hmmLength" : 76, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-16, "score" : 60.4, "envelopeStart" : 966, "envelopeEnd" : 1042, "postProcessed" : true, "location-fragments" : [ { "start" : 966, "end" : 1042, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-33, "score" : 114.6, "model-ac" : "PF13193" }, { "signature" : { "accession" : "G3DSA:3.30.300.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 951, "end" : 1053, "hmmStart" : 1, "hmmEnd" : 99, "hmmLength" : 109, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-25, "score" : 91.3, "envelopeStart" : 951, "envelopeEnd" : 1053, "postProcessed" : true, "location-fragments" : [ { "start" : 951, "end" : 1053, "dc-status" : "CONTINUOUS" } ] }, { "start" : 420, "end" : 524, "hmmStart" : 2, "hmmEnd" : 102, "hmmLength" : 109, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.5E-25, "score" : 91.0, "envelopeStart" : 418, "envelopeEnd" : 524, "postProcessed" : true, "location-fragments" : [ { "start" : 420, "end" : 524, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-54, "score" : 184.9, "model-ac" : "2d1sA04" }, { "signature" : { "accession" : "G3DSA:3.40.50.980", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 555, "end" : 728, "hmmStart" : 3, "hmmEnd" : 386, "hmmLength" : 159, "hmmBounds" : "INCOMPLETE", "evalue" : 6.6E-92, "score" : 310.2, "envelopeStart" : 550, "envelopeEnd" : 950, "postProcessed" : true, "location-fragments" : [ { "start" : 555, "end" : 728, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-188, "score" : 628.2, "model-ac" : "2d1sA03" }, { "signature" : { "accession" : "G3DSA:2.30.38.10", "name" : "Luciferase; Domain 3", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 872, "end" : 950, "hmmStart" : 3, "hmmEnd" : 386, "hmmLength" : 94, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 6.6E-92, "score" : 310.2, "envelopeStart" : 550, "envelopeEnd" : 950, "postProcessed" : true, "location-fragments" : [ { "start" : 872, "end" : 950, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-188, "score" : 628.2, "model-ac" : "2d1sA01" }, { "signature" : { "accession" : "cd05911", "name" : "Firefly_Luc_like", "description" : "Firefly_Luc_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 545, "end" : 1043, "sites" : [ { "description" : "acyl-activating enzyme (AAE) consensus motif", "numLocations" : 9, "siteLocations" : [ { "start" : 715, "end" : 715, "residue" : "S" }, { "start" : 718, "end" : 718, "residue" : "T" }, { "start" : 716, "end" : 716, "residue" : "S" }, { "start" : 712, "end" : 712, "residue" : "I" }, { "start" : 717, "end" : 717, "residue" : "G" }, { "start" : 723, "end" : 723, "residue" : "K" }, { "start" : 719, "end" : 719, "residue" : "T" }, { "start" : 720, "end" : 720, "residue" : "G" }, { "start" : 722, "end" : 722, "residue" : "P" } ] }, { "description" : "AMP binding site", "numLocations" : 16, "siteLocations" : [ { "start" : 950, "end" : 950, "residue" : "R" }, { "start" : 952, "end" : 952, "residue" : "K" }, { "start" : 853, "end" : 853, "residue" : "Y" }, { "start" : 935, "end" : 935, "residue" : "D" }, { "start" : 852, "end" : 852, "residue" : "A" }, { "start" : 947, "end" : 947, "residue" : "Y" }, { "start" : 854, "end" : 854, "residue" : "G" }, { "start" : 956, "end" : 956, "residue" : "K" }, { "start" : 855, "end" : 855, "residue" : "L" }, { "start" : 954, "end" : 954, "residue" : "I" }, { "start" : 961, "end" : 961, "residue" : "Q" }, { "start" : 830, "end" : 830, "residue" : "P" }, { "start" : 757, "end" : 757, "residue" : "H" }, { "start" : 828, "end" : 828, "residue" : "A" }, { "start" : 829, "end" : 829, "residue" : "A" }, { "start" : 856, "end" : 856, "residue" : "T" } ] } ], "evalue" : 1.71706E-139, "score" : 427.399, "location-fragments" : [ { "start" : 545, "end" : 1043, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd05911" }, { "signature" : { "accession" : "PTHR24096", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 522, "hmmStart" : 40, "hmmEnd" : 534, "hmmLength" : 539, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 526, "location-fragments" : [ { "start" : 14, "end" : 522, "dc-status" : "CONTINUOUS" } ] }, { "start" : 540, "end" : 1050, "hmmStart" : 42, "hmmEnd" : 529, "hmmLength" : 539, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 524, "envelopeEnd" : 1057, "location-fragments" : [ { "start" : 540, "end" : 1050, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-233, "familyName" : "", "score" : 778.3, "model-ac" : "PTHR24096" }, { "signature" : { "accession" : "PF00501", "name" : "AMP-binding", "description" : "AMP-binding enzyme", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000873", "name" : "AMP-dep_Synth/Lig", "description" : "AMP-dependent synthetase/ligase", "type" : "DOMAIN", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 543, "end" : 957, "hmmStart" : 12, "hmmEnd" : 423, "hmmLength" : 424, "hmmBounds" : "INCOMPLETE", "evalue" : 2.0E-84, "score" : 283.6, "envelopeStart" : 532, "envelopeEnd" : 958, "postProcessed" : true, "location-fragments" : [ { "start" : 543, "end" : 957, "dc-status" : "CONTINUOUS" } ] }, { "start" : 16, "end" : 424, "hmmStart" : 10, "hmmEnd" : 423, "hmmLength" : 424, "hmmBounds" : "INCOMPLETE", "evalue" : 9.4E-81, "score" : 271.6, "envelopeStart" : 8, "envelopeEnd" : 425, "postProcessed" : true, "location-fragments" : [ { "start" : 16, "end" : 424, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-167, "score" : 557.1, "model-ac" : "PF00501" }, { "signature" : { "accession" : "G3DSA:3.40.50.980", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 552, "end" : 871, "hmmStart" : 3, "hmmEnd" : 386, "hmmLength" : 179, "hmmBounds" : "INCOMPLETE", "evalue" : 6.6E-92, "score" : 310.2, "envelopeStart" : 550, "envelopeEnd" : 950, "postProcessed" : true, "location-fragments" : [ { "start" : 552, "end" : 554, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 729, "end" : 871, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.6E-188, "score" : 628.2, "model-ac" : "2d1sA02" }, { "signature" : { "accession" : "PS00455", "name" : "AMP_BINDING", "description" : "Putative AMP-binding domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR020845", "name" : "AMP-binding_CS", "description" : "AMP-binding, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 712, "end" : 723, "level" : "STRONG", "cigarAlignment" : "9M1I2M", "alignment" : "ILTSSGTTGlPK", "location-fragments" : [ { "start" : 712, "end" : 723, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00455" }, { "signature" : { "accession" : "PTHR24096:SF353", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 522, "hmmStart" : 40, "hmmEnd" : 534, "hmmLength" : 539, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 526, "location-fragments" : [ { "start" : 14, "end" : 522, "dc-status" : "CONTINUOUS" } ] }, { "start" : 540, "end" : 1050, "hmmStart" : 42, "hmmEnd" : 529, "hmmLength" : 539, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 524, "envelopeEnd" : 1057, "location-fragments" : [ { "start" : 540, "end" : 1050, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-233, "familyName" : "", "score" : 778.3, "model-ac" : "PTHR24096:SF353" }, { "signature" : { "accession" : "G3DSA:3.40.50.12780", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042099", "name" : "AMP-dep_Synthh-like_sf", "description" : "AMP-dependent synthetase-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 419, "hmmStart" : 21, "hmmEnd" : 426, "hmmLength" : 427, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.2E-97, "score" : 327.3, "envelopeStart" : 1, "envelopeEnd" : 421, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 419, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-193, "score" : 643.5, "model-ac" : "4w8oB00" } ], "xref" : [ { "name" : "XP_018909776.1 PREDICTED: uncharacterized protein LOC109038953 [Bemisia tabaci]", "id" : "XP_018909776.1" } ] },{ "sequence" : "MPETSLVNGYQGNGHMEPEIPDGENFLFTSESVGEGHPDKMCDQISDAILDAHLKEDPDAKVACETVTKTGMVLLCGEITSKANVDYQKVVRDTIKHIGYDDSSKGFDYETCNVLVAMDAQSPNIAEGVHVNRAEDMIGAGDQGLMFGYATDETEECMPLTVVLAHKLNERIADMRRSGVFWWARPDSKTQVTCEYCFQHGACVPLRVHTVVVSIQHSEKITLEELRTEIMNKVIKEVIPTKYLDDKTMFHINPCGQFVLGGPRCDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKSGLCRRCLVQVSYAIGVAEPISITLFEYGTAKKTQKELLEIVKRNFDLRPGKIVRDLNLRNPIYQKTSTYGHFGRDIFPWEQPKLLV", "md5" : "7a792ed98c6846ca8a5035a2452ca474", "matches" : [ { "signature" : { "accession" : "cd18079", "name" : "S-AdoMet_synt", "description" : "S-AdoMet_synt", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 27, "end" : 399, "sites" : [ { "description" : "active site", "numLocations" : 28, "siteLocations" : [ { "start" : 142, "end" : 142, "residue" : "D" }, { "start" : 38, "end" : 38, "residue" : "P" }, { "start" : 289, "end" : 289, "residue" : "A" }, { "start" : 121, "end" : 121, "residue" : "Q" }, { "start" : 189, "end" : 189, "residue" : "K" }, { "start" : 63, "end" : 63, "residue" : "A" }, { "start" : 260, "end" : 260, "residue" : "L" }, { "start" : 273, "end" : 273, "residue" : "K" }, { "start" : 187, "end" : 187, "residue" : "D" }, { "start" : 214, "end" : 214, "residue" : "S" }, { "start" : 78, "end" : 78, "residue" : "E" }, { "start" : 287, "end" : 287, "residue" : "G" }, { "start" : 37, "end" : 37, "residue" : "H" }, { "start" : 297, "end" : 297, "residue" : "K" }, { "start" : 272, "end" : 272, "residue" : "R" }, { "start" : 125, "end" : 125, "residue" : "I" }, { "start" : 288, "end" : 288, "residue" : "G" }, { "start" : 39, "end" : 39, "residue" : "D" }, { "start" : 258, "end" : 258, "residue" : "F" }, { "start" : 255, "end" : 255, "residue" : "C" }, { "start" : 299, "end" : 299, "residue" : "D" }, { "start" : 31, "end" : 31, "residue" : "E" }, { "start" : 257, "end" : 257, "residue" : "Q" }, { "start" : 293, "end" : 293, "residue" : "K" }, { "start" : 330, "end" : 330, "residue" : "I" }, { "start" : 266, "end" : 266, "residue" : "D" }, { "start" : 141, "end" : 141, "residue" : "G" }, { "start" : 124, "end" : 124, "residue" : "N" } ] }, { "description" : "ATP binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 187, "end" : 187, "residue" : "D" }, { "start" : 38, "end" : 38, "residue" : "P" }, { "start" : 31, "end" : 31, "residue" : "E" }, { "start" : 189, "end" : 189, "residue" : "K" }, { "start" : 37, "end" : 37, "residue" : "H" }, { "start" : 273, "end" : 273, "residue" : "K" } ] }, { "description" : "homodimer interface", "numLocations" : 50, "siteLocations" : [ { "start" : 65, "end" : 65, "residue" : "E" }, { "start" : 267, "end" : 267, "residue" : "A" }, { "start" : 289, "end" : 289, "residue" : "A" }, { "start" : 327, "end" : 327, "residue" : "S" }, { "start" : 339, "end" : 339, "residue" : "T" }, { "start" : 78, "end" : 78, "residue" : "E" }, { "start" : 254, "end" : 254, "residue" : "P" }, { "start" : 265, "end" : 265, "residue" : "C" }, { "start" : 143, "end" : 143, "residue" : "Q" }, { "start" : 286, "end" : 286, "residue" : "G" }, { "start" : 145, "end" : 145, "residue" : "L" }, { "start" : 76, "end" : 76, "residue" : "C" }, { "start" : 282, "end" : 282, "residue" : "W" }, { "start" : 336, "end" : 336, "residue" : "I" }, { "start" : 331, "end" : 331, "residue" : "G" }, { "start" : 212, "end" : 212, "residue" : "V" }, { "start" : 329, "end" : 329, "residue" : "A" }, { "start" : 269, "end" : 269, "residue" : "L" }, { "start" : 69, "end" : 69, "residue" : "K" }, { "start" : 271, "end" : 271, "residue" : "G" }, { "start" : 280, "end" : 280, "residue" : "G" }, { "start" : 77, "end" : 77, "residue" : "G" }, { "start" : 142, "end" : 142, "residue" : "D" }, { "start" : 189, "end" : 189, "residue" : "K" }, { "start" : 144, "end" : 144, "residue" : "G" }, { "start" : 147, "end" : 147, "residue" : "F" }, { "start" : 283, "end" : 283, "residue" : "G" }, { "start" : 287, "end" : 287, "residue" : "G" }, { "start" : 27, "end" : 27, "residue" : "L" }, { "start" : 210, "end" : 210, "residue" : "T" }, { "start" : 29, "end" : 29, "residue" : "T" }, { "start" : 251, "end" : 251, "residue" : "H" }, { "start" : 325, "end" : 325, "residue" : "Q" }, { "start" : 67, "end" : 67, "residue" : "V" }, { "start" : 74, "end" : 74, "residue" : "L" }, { "start" : 272, "end" : 272, "residue" : "R" }, { "start" : 193, "end" : 193, "residue" : "T" }, { "start" : 328, "end" : 328, "residue" : "Y" }, { "start" : 285, "end" : 285, "residue" : "H" }, { "start" : 270, "end" : 270, "residue" : "T" }, { "start" : 281, "end" : 281, "residue" : "G" }, { "start" : 337, "end" : 337, "residue" : "S" }, { "start" : 31, "end" : 31, "residue" : "E" }, { "start" : 28, "end" : 28, "residue" : "F" }, { "start" : 293, "end" : 293, "residue" : "K" }, { "start" : 330, "end" : 330, "residue" : "I" }, { "start" : 266, "end" : 266, "residue" : "D" }, { "start" : 275, "end" : 275, "residue" : "I" }, { "start" : 191, "end" : 191, "residue" : "Q" }, { "start" : 284, "end" : 284, "residue" : "A" } ] } ], "evalue" : 0.0, "score" : 678.74, "location-fragments" : [ { "start" : 27, "end" : 399, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18079" }, { "signature" : { "accession" : "MF_00086", "name" : "S_AdoMet_synth1", "description" : "S-adenosylmethionine synthase [metK].", "signatureLibraryRelease" : { "library" : "HAMAP", "version" : "2020_01" }, "entry" : { "accession" : "IPR002133", "name" : "S-AdoMet_synthetase", "description" : "S-adenosylmethionine synthetase", "type" : "FAMILY", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 24, "end" : 402, "score" : 49.917, "alignment" : "ENFLFTSESVGEGHPDKMCDQISDAILDAHLKEDPDAKVACETVTKTGMVLLCGEITSKANVDYQKVVRDTIKHIGYDDSSKGFDYETCNVLVAMDAQSPNIAEGVHVNRAeDMIGAGDQGLMFGYATDETEECMPLTVVLAHKLNERIADMRRSGVFWWARPDSKTQVTCEYCFQHgacvPLRVHTVVVSIQHSEKITLEELRTEIMNKVIKEVIPTKYLDD-KTMFHINPCGQFVLGGPRCDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKSGLCRRCLVQVSYAIGVAEPISITLFEYGTAKKTQKELLEIVKRNFDLRPGKIVRDLNLRNPIYQKTSTYGHFGRDIFPWEQP------KLLV", "location-fragments" : [ { "start" : 24, "end" : 402, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "MF_00086" }, { "signature" : { "accession" : "SSF55973", "name" : "S-adenosylmethionine synthetase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR022636", "name" : "S-AdoMet_synthetase_sfam", "description" : "S-adenosylmethionine synthetase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" } ], "pathwayXRefs" : [ { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 25, "end" : 132, "hmmLength" : 110, "location-fragments" : [ { "start" : 25, "end" : 132, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.29E-47, "model-ac" : "0054441" }, { "signature" : { "accession" : "PF00438", "name" : "S-AdoMet_synt_N", "description" : "S-adenosylmethionine synthetase, N-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022628", "name" : "S-AdoMet_synt_N", "description" : "S-adenosylmethionine synthetase, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" } ] } }, "locations" : [ { "start" : 25, "end" : 123, "hmmStart" : 1, "hmmEnd" : 99, "hmmLength" : 99, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-43, "score" : 147.8, "envelopeStart" : 25, "envelopeEnd" : 123, "postProcessed" : true, "location-fragments" : [ { "start" : 25, "end" : 123, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-45, "score" : 153.6, "model-ac" : "PF00438" }, { "signature" : { "accession" : "G3DSA:3.30.300.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 33, "end" : 299, "hmmStart" : 1, "hmmEnd" : 368, "hmmLength" : 141, "hmmBounds" : "INCOMPLETE", "evalue" : 2.1E-173, "score" : 578.5, "envelopeStart" : 27, "envelopeEnd" : 396, "postProcessed" : true, "location-fragments" : [ { "start" : 33, "end" : 136, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 263, "end" : 299, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.9E-173, "score" : 578.6, "model-ac" : "5a1iA02" }, { "signature" : { "accession" : "PTHR11964", "name" : "S-ADENOSYLMETHIONINE SYNTHETASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR002133", "name" : "S-AdoMet_synthetase", "description" : "S-adenosylmethionine synthetase", "type" : "FAMILY", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 16, "end" : 401, "hmmStart" : 9, "hmmEnd" : 394, "hmmLength" : 396, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 402, "location-fragments" : [ { "start" : 16, "end" : 401, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-219, "familyName" : "S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1", "score" : 729.4, "model-ac" : "PTHR11964" }, { "signature" : { "accession" : "PS00377", "name" : "ADOMET_SYNTHASE_2", "description" : "S-adenosylmethionine synthase signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR022631", "name" : "ADOMET_SYNTHASE_CS", "description" : "S-adenosylmethionine synthetase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" } ] } }, "locations" : [ { "start" : 286, "end" : 294, "level" : "STRONG", "cigarAlignment" : "6M1I2M", "alignment" : "GGGAFSgKD", "location-fragments" : [ { "start" : 286, "end" : 294, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00377" }, { "signature" : { "accession" : "SSF55973", "name" : "S-adenosylmethionine synthetase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR022636", "name" : "S-AdoMet_synthetase_sfam", "description" : "S-adenosylmethionine synthetase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" } ], "pathwayXRefs" : [ { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 136, "end" : 259, "hmmLength" : 126, "location-fragments" : [ { "start" : 136, "end" : 259, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.79E-50, "model-ac" : "0054442" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 23, "location-fragments" : [ { "start" : 1, "end" : 23, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF02773", "name" : "S-AdoMet_synt_C", "description" : "S-adenosylmethionine synthetase, C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022630", "name" : "S-AdoMet_synt_C", "description" : "S-adenosylmethionine synthetase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" } ], "pathwayXRefs" : [ { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 260, "end" : 397, "hmmStart" : 1, "hmmEnd" : 138, "hmmLength" : 138, "hmmBounds" : "COMPLETE", "evalue" : 2.6E-66, "score" : 221.8, "envelopeStart" : 260, "envelopeEnd" : 397, "postProcessed" : true, "location-fragments" : [ { "start" : 260, "end" : 397, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-66, "score" : 223.0, "model-ac" : "PF02773" }, { "signature" : { "accession" : "G3DSA:3.30.300.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 137, "end" : 396, "hmmStart" : 1, "hmmEnd" : 368, "hmmLength" : 128, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.1E-173, "score" : 578.5, "envelopeStart" : 27, "envelopeEnd" : 396, "postProcessed" : true, "location-fragments" : [ { "start" : 300, "end" : 396, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 137, "end" : 159, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.9E-173, "score" : 578.6, "model-ac" : "5a1iA03" }, { "signature" : { "accession" : "G3DSA:3.30.300.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 27, "end" : 262, "hmmStart" : 1, "hmmEnd" : 368, "hmmLength" : 125, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.1E-173, "score" : 578.5, "envelopeStart" : 27, "envelopeEnd" : 396, "postProcessed" : true, "location-fragments" : [ { "start" : 27, "end" : 32, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 160, "end" : 262, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.9E-173, "score" : 578.6, "model-ac" : "5a1iA01" }, { "signature" : { "accession" : "PF02772", "name" : "S-AdoMet_synt_M", "description" : "S-adenosylmethionine synthetase, central domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022629", "name" : "S-AdoMet_synt_central", "description" : "S-adenosylmethionine synthetase, central domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" } ] } }, "locations" : [ { "start" : 138, "end" : 258, "hmmStart" : 2, "hmmEnd" : 120, "hmmLength" : 120, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.7E-45, "score" : 152.0, "envelopeStart" : 137, "envelopeEnd" : 258, "postProcessed" : true, "location-fragments" : [ { "start" : 138, "end" : 258, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-45, "score" : 152.8, "model-ac" : "PF02772" }, { "signature" : { "accession" : "SSF55973", "name" : "S-adenosylmethionine synthetase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR022636", "name" : "S-AdoMet_synthetase_sfam", "description" : "S-adenosylmethionine synthetase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" } ], "pathwayXRefs" : [ { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 260, "end" : 400, "hmmLength" : 152, "location-fragments" : [ { "start" : 260, "end" : 400, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.86E-64, "model-ac" : "0041133" }, { "signature" : { "accession" : "PIRSF000497", "name" : "MAT", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR002133", "name" : "S-AdoMet_synthetase", "description" : "S-adenosylmethionine synthetase", "type" : "FAMILY", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 21, "end" : 402, "hmmStart" : 24, "hmmEnd" : 400, "hmmLength" : 389, "hmmBounds" : "INCOMPLETE", "evalue" : 1.0E-162, "score" : 537.2, "envelopeStart" : 21, "envelopeEnd" : 402, "postProcessed" : false, "location-fragments" : [ { "start" : 21, "end" : 402, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-163, "score" : 537.5, "model-ac" : "PIRSF000497" }, { "signature" : { "accession" : "PS00376", "name" : "ADOMET_SYNTHASE_1", "description" : "S-adenosylmethionine synthase signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR022631", "name" : "ADOMET_SYNTHASE_CS", "description" : "S-adenosylmethionine synthetase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" } ] } }, "locations" : [ { "start" : 139, "end" : 149, "level" : "STRONG", "cigarAlignment" : "6M3I2M", "alignment" : "GAGDQGlmfGY", "location-fragments" : [ { "start" : 139, "end" : 149, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00376" }, { "signature" : { "accession" : "PTHR11964:SF11", "name" : "S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 401, "hmmStart" : 9, "hmmEnd" : 394, "hmmLength" : 396, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 402, "location-fragments" : [ { "start" : 16, "end" : 401, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-219, "familyName" : "S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1", "score" : 729.4, "model-ac" : "PTHR11964:SF11" }, { "signature" : { "accession" : "TIGR01034", "name" : "TIGR01034", "description" : "metK: methionine adenosyltransferase", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR002133", "name" : "S-AdoMet_synthetase", "description" : "S-adenosylmethionine synthetase", "type" : "FAMILY", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 27, "end" : 400, "hmmStart" : 1, "hmmEnd" : 369, "hmmLength" : 377, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 9.1E-179, "score" : 592.2, "envelopeStart" : 27, "envelopeEnd" : 402, "postProcessed" : false, "location-fragments" : [ { "start" : 27, "end" : 400, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.1E-179, "score" : 592.3, "model-ac" : "TIGR01034" } ], "xref" : [ { "name" : "XP_018910512.1 PREDICTED: S-adenosylmethionine synthase isoform X4 [Bemisia tabaci]", "id" : "XP_018910512.1" } ] },{ "sequence" : "MLTVNDPGSGLGYVLSACVLLASFNSPAYGTEDPEAHNLRHQRLQPEFAGPIDNLTVPVGKEVSLSCVVNNLGEHKVGWLRSRDQTILTLHTRVVTHSPRISISFDNHRTFTLHISRVKESDKGCYMCQVNTPEMKKQSGCIDVHVPPDIISEYSSSDTAVNEGDNVTLSCHATGHPQPIVTWRRENGEPMLIRKNVRDLTLVDVHRGKTLFLWKVDRRQMGAYLCIAANEVPPAVSKRVIVSVNFQPTIVIPNQLVGSPLGKEVHLECYAEAYPKTINYWVKNRGEILLEGSDSRAKYTIQENRSVYKVYMSLFIKDFNMSDVGTYNCVATNSLGRAEATIRLYNLTGAGGSGQDHPEDSENSARCSKHSIRPFLLILCLLYVSRFLSSR", "md5" : "44e65e79fc283c70df60c29c7fe0f7bf", "matches" : [ { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 151, "end" : 244, "hmmStart" : 5, "hmmEnd" : 94, "hmmLength" : 96, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 8.3E-21, "score" : 76.0, "envelopeStart" : 151, "envelopeEnd" : 245, "postProcessed" : true, "location-fragments" : [ { "start" : 151, "end" : 244, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-50, "score" : 170.0, "model-ac" : "5eo9B02" }, { "signature" : { "accession" : "SSF48726", "name" : "Immunoglobulin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036179", "name" : "Ig-like_dom_sf", "description" : "Immunoglobulin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 147, "end" : 252, "hmmLength" : 111, "location-fragments" : [ { "start" : 147, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.12E-17, "model-ac" : "0035573" }, { "signature" : { "accession" : "SSF48726", "name" : "Immunoglobulin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036179", "name" : "Ig-like_dom_sf", "description" : "Immunoglobulin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 151, "hmmLength" : 126, "location-fragments" : [ { "start" : 46, "end" : 151, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.77E-17, "model-ac" : "0042359" }, { "signature" : { "accession" : "PTHR12231:SF235", "name" : "DPR-INTERACTING PROTEIN GAMMA", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 43, "end" : 356, "hmmStart" : 18, "hmmEnd" : 348, "hmmLength" : 400, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 28, "envelopeEnd" : 389, "location-fragments" : [ { "start" : 43, "end" : 356, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-137, "familyName" : "DPR-INTERACTING PROTEIN GAMMA", "score" : 458.9, "model-ac" : "PTHR12231:SF235" }, { "signature" : { "accession" : "PF07679", "name" : "I-set", "description" : "Immunoglobulin I-set domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013098", "name" : "Ig_I-set", "description" : "Immunoglobulin I-set", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 139, "hmmStart" : 1, "hmmEnd" : 83, "hmmLength" : 90, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.6E-11, "score" : 44.1, "envelopeStart" : 46, "envelopeEnd" : 146, "postProcessed" : true, "location-fragments" : [ { "start" : 46, "end" : 139, "dc-status" : "CONTINUOUS" } ] }, { "start" : 250, "end" : 344, "hmmStart" : 3, "hmmEnd" : 88, "hmmLength" : 90, "hmmBounds" : "INCOMPLETE", "evalue" : 4.8E-11, "score" : 42.6, "envelopeStart" : 248, "envelopeEnd" : 345, "postProcessed" : true, "location-fragments" : [ { "start" : 250, "end" : 344, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-40, "score" : 135.5, "model-ac" : "PF07679" }, { "signature" : { "accession" : "SM00409", "name" : "IG_3c", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003599", "name" : "Ig_sub", "description" : "Immunoglobulin subtype", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 52, "end" : 147, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-8, "score" : 44.0, "location-fragments" : [ { "start" : 52, "end" : 147, "dc-status" : "CONTINUOUS" } ] }, { "start" : 253, "end" : 347, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 0.014, "score" : 24.5, "location-fragments" : [ { "start" : 253, "end" : 347, "dc-status" : "CONTINUOUS" } ] }, { "start" : 156, "end" : 245, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-7, "score" : 41.4, "location-fragments" : [ { "start" : 156, "end" : 245, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-28, "score" : 109.9, "model-ac" : "SM00409" }, { "signature" : { "accession" : "PTHR12231", "name" : "CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 43, "end" : 356, "hmmStart" : 18, "hmmEnd" : 348, "hmmLength" : 400, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 28, "envelopeEnd" : 389, "location-fragments" : [ { "start" : 43, "end" : 356, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-137, "familyName" : "DPR-INTERACTING PROTEIN GAMMA", "score" : 458.9, "model-ac" : "PTHR12231" }, { "signature" : { "accession" : "cd00096", "name" : "Ig", "description" : "Ig", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 265, "end" : 343, "sites" : [ ], "evalue" : 9.32122E-10, "score" : 52.6296, "location-fragments" : [ { "start" : 265, "end" : 343, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00096" }, { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 245, "end" : 347, "hmmStart" : 4, "hmmEnd" : 113, "hmmLength" : 122, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.3E-20, "score" : 73.1, "envelopeStart" : 244, "envelopeEnd" : 347, "postProcessed" : true, "location-fragments" : [ { "start" : 245, "end" : 347, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-48, "score" : 163.9, "model-ac" : "4yfcB03" }, { "signature" : { "accession" : "PS50835", "name" : "IG_LIKE", "description" : "Ig-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR007110", "name" : "Ig-like_dom", "description" : "Immunoglobulin-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 148, "end" : 237, "score" : 12.713, "alignment" : "PDIISEYssSDTAVNEGDNVTLSCHATG-HPQPIVTWRRENG--------EPMLIrknvrdltlvdVHRGKTLFLWKVDRRQMGAYLCIAAN-----EVPPAVS", "location-fragments" : [ { "start" : 148, "end" : 237, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50835" }, { "signature" : { "accession" : "SSF48726", "name" : "Immunoglobulin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036179", "name" : "Ig-like_dom_sf", "description" : "Immunoglobulin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 245, "end" : 344, "hmmLength" : 110, "location-fragments" : [ { "start" : 245, "end" : 344, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.38E-17, "model-ac" : "0037210" }, { "signature" : { "accession" : "SM00408", "name" : "igc2_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003598", "name" : "Ig_sub2", "description" : "Immunoglobulin subtype 2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 260, "end" : 336, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 56, "hmmBounds" : "COMPLETE", "evalue" : 0.038, "score" : 20.7, "location-fragments" : [ { "start" : 260, "end" : 336, "dc-status" : "CONTINUOUS" } ] }, { "start" : 162, "end" : 233, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 56, "hmmBounds" : "COMPLETE", "evalue" : 6.6E-8, "score" : 42.3, "location-fragments" : [ { "start" : 162, "end" : 233, "dc-status" : "CONTINUOUS" } ] }, { "start" : 58, "end" : 135, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 56, "hmmBounds" : "COMPLETE", "evalue" : 0.18, "score" : 14.4, "location-fragments" : [ { "start" : 58, "end" : 135, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-18, "score" : 77.4, "model-ac" : "SM00408" }, { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 150, "hmmStart" : 4, "hmmEnd" : 109, "hmmLength" : 110, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-32, "score" : 112.9, "envelopeStart" : 42, "envelopeEnd" : 150, "postProcessed" : true, "location-fragments" : [ { "start" : 42, "end" : 150, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-53, "score" : 181.6, "model-ac" : "5eo9B01" }, { "signature" : { "accession" : "PF13927", "name" : "Ig_3", "description" : "Immunoglobulin domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 147, "end" : 230, "hmmStart" : 1, "hmmEnd" : 79, "hmmLength" : 79, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-13, "score" : 51.4, "envelopeStart" : 147, "envelopeEnd" : 230, "postProcessed" : true, "location-fragments" : [ { "start" : 147, "end" : 230, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-38, "score" : 129.8, "model-ac" : "PF13927" }, { "signature" : { "accession" : "PS50835", "name" : "IG_LIKE", "description" : "Ig-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR007110", "name" : "Ig-like_dom", "description" : "Immunoglobulin-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 139, "score" : 10.644, "alignment" : "PEFAGPIDNLTVPVGKEVSLSCVVNN-LGEHKVGWLRS----------RDQTIltlhtrvvthsprisisfdNHRTFTLHISRVKESDKGCYMCQVN-----TPEMKKQS", "location-fragments" : [ { "start" : 46, "end" : 139, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50835" }, { "signature" : { "accession" : "PS50835", "name" : "IG_LIKE", "description" : "Ig-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR007110", "name" : "Ig-like_dom", "description" : "Immunoglobulin-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 248, "end" : 343, "score" : 10.444, "alignment" : "PTIVIPNQLVGSPLGKEVHLECYAEA-YPKTINYWVKNRGeillegsdSRAKYTIQENRSVYKVYMSLFIKDFNMSDVGTYNCVATN--SLGRAEATIR", "location-fragments" : [ { "start" : 248, "end" : 343, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50835" }, { "signature" : { "accession" : "SM00406", "name" : "igv1_8", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013106", "name" : "Ig_V-set", "description" : "Immunoglobulin V-set domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 264, "end" : 331, "hmmStart" : 1, "hmmEnd" : 76, "hmmLength" : 76, "hmmBounds" : "COMPLETE", "evalue" : 0.63, "score" : 6.6, "location-fragments" : [ { "start" : 264, "end" : 331, "dc-status" : "CONTINUOUS" } ] }, { "start" : 62, "end" : 130, "hmmStart" : 1, "hmmEnd" : 76, "hmmLength" : 76, "hmmBounds" : "COMPLETE", "evalue" : 7.7E-6, "score" : 35.4, "location-fragments" : [ { "start" : 62, "end" : 130, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.7E-8, "score" : 42.0, "model-ac" : "SM00406" } ], "xref" : [ { "name" : "XP_018910310.1 PREDICTED: lachesin-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910310.1" } ] },{ "sequence" : "MGQLPESRVVPAARCFLKVGTDFGGPYLIKDSKRRNAPSRKAYICLFICLATKAIHLELVSDLTTEAFIAALERFTSRRGMCTDIFSDNGSNFKGTNNYLDELYEFLREDKSNEMVTKHLTSKNIKWHFSPPIGSHFGGIWEAGIKSVKFHLKRILGDQKLTFEEFTTLLTRIEAILNSRPLCPISSDVEDLNVLTPAHFLIGGPLLSLPEYDWSSTPSNRLSRWQLLQQITQQYWKQWSLEYLNTLQQRAKWRTQAAETLAVGDLVLIKDENAPSLQWQMGRVIELHPGKDGIVRVASVKTTANTLRRPLVKLFRLPVD", "md5" : "0ddac640124571dfa87f024fca4e1bf9", "matches" : [ { "signature" : { "accession" : "PTHR22955", "name" : "RETROTRANSPOSON", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 310, "hmmStart" : 1176, "hmmEnd" : 1453, "hmmLength" : 1456, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 313, "location-fragments" : [ { "start" : 1, "end" : 310, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-82, "familyName" : "", "score" : 280.4, "model-ac" : "PTHR22955" }, { "signature" : { "accession" : "PS50994", "name" : "INTEGRASE", "description" : "Integrase catalytic domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001584", "name" : "Integrase_cat-core", "description" : "Integrase, catalytic core", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA integration", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0015074" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 205, "score" : 11.04, "alignment" : "SRVVPaarcFLKVGTDFGGPYLIKdskrrnapSRKAYICLFICLATKAIHLELVSDLTTEAFIAALERFTSRR-GMCTDIFSDNGSNFkgtnnyldelyeflredkSNEMVTKHLTSKNIKWHFSPPIGSHFGGIWEAGIKSVKFHLKRILGDQKltFEEFTTLLTRIEAILNSRPLcpissdvEDLNVLTPAHFLIGGP", "location-fragments" : [ { "start" : 7, "end" : 205, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50994" }, { "signature" : { "accession" : "PTHR22955:SF60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 310, "hmmStart" : 1176, "hmmEnd" : 1453, "hmmLength" : 1456, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 313, "location-fragments" : [ { "start" : 1, "end" : 310, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-82, "familyName" : "", "score" : 280.4, "model-ac" : "PTHR22955:SF60" }, { "signature" : { "accession" : "G3DSA:3.30.420.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036397", "name" : "RNaseH_sf", "description" : "Ribonuclease H superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 238, "hmmStart" : 11, "hmmEnd" : 148, "hmmLength" : 200, "hmmBounds" : "COMPLETE", "evalue" : 6.9E-9, "score" : 37.2, "envelopeStart" : 7, "envelopeEnd" : 238, "postProcessed" : true, "location-fragments" : [ { "start" : 7, "end" : 238, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-9, "score" : 39.6, "model-ac" : "2x78A00" }, { "signature" : { "accession" : "SSF53098", "name" : "Ribonuclease H-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR012337", "name" : "RNaseH-like_sf", "description" : "Ribonuclease H-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 12, "end" : 183, "hmmLength" : 168, "location-fragments" : [ { "start" : 12, "end" : 183, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-18, "model-ac" : "0046055" }, { "signature" : { "accession" : "PF18701", "name" : "DUF5641", "description" : "Family of unknown function (DUF5641)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR040676", "name" : "DUF5641", "description" : "Domain of unknown function DUF5641", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 223, "end" : 317, "hmmStart" : 1, "hmmEnd" : 94, "hmmLength" : 94, "hmmBounds" : "COMPLETE", "evalue" : 5.2E-36, "score" : 122.7, "envelopeStart" : 223, "envelopeEnd" : 317, "postProcessed" : true, "location-fragments" : [ { "start" : 223, "end" : 317, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-36, "score" : 123.4, "model-ac" : "PF18701" } ], "xref" : [ { "name" : "XP_018910559.1 PREDICTED: uncharacterized protein LOC109039514 [Bemisia tabaci]", "id" : "XP_018910559.1" } ] },{ "sequence" : "MTKSSDSKSEPVKINKWDGSAVKNALDDAVAEVLTSKFSYIENYKLVDGRLLICGLAVAVALFAIVWDLYFYPFPESKPVLIFSVTTYFFLMGVLTLYTTYVEKGTFIVCAPKNQGIRWEAGSILKKYDDIYTLVLACTDKKTGSVREASFNKSVACFIDENGTVLDDLVENEVVKLHNGLLSEKKDN", "md5" : "6a2a61e57c4bf5899438ac2120d41623", "matches" : [ { "signature" : { "accession" : "PTHR13085", "name" : "MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR009582", "name" : "Spc2/SPCS2", "description" : "Signal peptidase complex subunit Spc2/SPCS2", "type" : "FAMILY", "goXRefs" : [ { "name" : "signal peptide processing", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006465" }, { "name" : "signal peptidase complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005787" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ { "name" : "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)", "databaseName" : "Reactome", "id" : "R-HSA-400511" }, { "name" : "Synthesis, secretion, and deacylation of Ghrelin", "databaseName" : "Reactome", "id" : "R-HSA-422085" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)", "databaseName" : "Reactome", "id" : "R-HSA-381771" } ] } }, "locations" : [ { "start" : 4, "end" : 186, "hmmStart" : 6, "hmmEnd" : 190, "hmmLength" : 192, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 188, "location-fragments" : [ { "start" : 4, "end" : 186, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-59, "familyName" : "MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT", "score" : 202.4, "model-ac" : "PTHR13085" }, { "signature" : { "accession" : "PF06703", "name" : "SPC25", "description" : "Microsomal signal peptidase 25 kDa subunit (SPC25)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR009582", "name" : "Spc2/SPCS2", "description" : "Signal peptidase complex subunit Spc2/SPCS2", "type" : "FAMILY", "goXRefs" : [ { "name" : "signal peptide processing", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006465" }, { "name" : "signal peptidase complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005787" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ { "name" : "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)", "databaseName" : "Reactome", "id" : "R-HSA-400511" }, { "name" : "Synthesis, secretion, and deacylation of Ghrelin", "databaseName" : "Reactome", "id" : "R-HSA-422085" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)", "databaseName" : "Reactome", "id" : "R-HSA-381771" } ] } }, "locations" : [ { "start" : 21, "end" : 178, "hmmStart" : 1, "hmmEnd" : 161, "hmmLength" : 162, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.1E-40, "score" : 137.2, "envelopeStart" : 21, "envelopeEnd" : 179, "postProcessed" : true, "location-fragments" : [ { "start" : 21, "end" : 178, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-40, "score" : 137.4, "model-ac" : "PF06703" } ], "xref" : [ { "name" : "XP_018910057.1 PREDICTED: probable signal peptidase complex subunit 2 [Bemisia tabaci]", "id" : "XP_018910057.1" } ] },{ "sequence" : "MFQKSELWIINVLLCISLSERVMTDLTPEEEEALIEAREDDELMKIIVIEMIRDNDNCRDYWPWSLQNDGVYGPTEVHCNHACNLISDLYLMNGGGDNKTRITDGGRCKNSWTIFKRCMCRLKDHTMPKYRWRTLHFITKRYLGPVMVKYLNHTTYMPPVITIPDPNFTKDYLYRESTDPWKDFWH", "md5" : "1707512de1aeacd16eafbf2a97c78358", "matches" : [ ], "xref" : [ { "name" : "XP_018909782.1 PREDICTED: uncharacterized protein LOC109038959 [Bemisia tabaci]", "id" : "XP_018909782.1" } ] },{ "sequence" : "MHLLWVIVISVICLGDLPSSFAQWGSDYPSLSTLIEDLKFLGGELGEYKDMVPSEVEQQVSALRDIDQFCPNSLDLEDVQLPRVFDARNQWKECAGLIGTPWDQGNCRSSSVLAVASMAADRLCISSNGTVKSTLSAQYLMACSSACEVNELLSTPLEFMKHTGIPTGSPYASDNTTRSGCVPYEIMPCNHSNTPVNPDEISLEPCDYNDKYSPLECPEECTNPVYPKKLDEDYYKWIYRHYGYGPYIRIQHVKIIGWGVEKKVPYWLGVNFFGDAWGMNGLFKFFRGRNHLFIETMVAAGRF", "md5" : "889cfbbd43d51d94f81a94cf3f8b79e2", "matches" : [ { "signature" : { "accession" : "SM00645", "name" : "pept_c1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 81, "end" : 302, "hmmStart" : 1, "hmmEnd" : 340, "hmmLength" : 340, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-9, "score" : 41.3, "location-fragments" : [ { "start" : 81, "end" : 302, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-9, "score" : 41.3, "model-ac" : "SM00645" }, { "signature" : { "accession" : "SSF54001", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038765", "name" : "Papain-like_cys_pep_sf", "description" : "Papain-like cysteine peptidase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 301, "hmmLength" : 313, "location-fragments" : [ { "start" : 46, "end" : 301, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.09E-35, "model-ac" : "0040950" }, { "signature" : { "accession" : "PF00112", "name" : "Peptidase_C1", "description" : "Papain family cysteine protease", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 81, "end" : 299, "hmmStart" : 1, "hmmEnd" : 215, "hmmLength" : 218, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.5E-19, "score" : 71.0, "envelopeStart" : 81, "envelopeEnd" : 302, "postProcessed" : true, "location-fragments" : [ { "start" : 81, "end" : 299, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-20, "score" : 72.3, "model-ac" : "PF00112" }, { "signature" : { "accession" : "PTHR12411", "name" : "CYSTEINE PROTEASE FAMILY C1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 75, "end" : 234, "hmmStart" : 168, "hmmEnd" : 299, "hmmLength" : 413, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 62, "envelopeEnd" : 237, "location-fragments" : [ { "start" : 75, "end" : 234, "dc-status" : "CONTINUOUS" } ] }, { "start" : 237, "end" : 297, "hmmStart" : 350, "hmmEnd" : 409, "hmmLength" : 413, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 231, "envelopeEnd" : 301, "location-fragments" : [ { "start" : 237, "end" : 297, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-32, "familyName" : "", "score" : 116.4, "model-ac" : "PTHR12411" }, { "signature" : { "accession" : "PTHR12411:SF356", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 75, "end" : 234, "hmmStart" : 168, "hmmEnd" : 299, "hmmLength" : 413, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 62, "envelopeEnd" : 237, "location-fragments" : [ { "start" : 75, "end" : 234, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-32, "familyName" : "", "score" : 116.4, "model-ac" : "PTHR12411:SF356" }, { "signature" : { "accession" : "G3DSA:3.90.70.10", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 39, "end" : 235, "hmmStart" : 68, "hmmEnd" : 208, "hmmLength" : 321, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.3E-23, "score" : 84.0, "envelopeStart" : 39, "envelopeEnd" : 239, "postProcessed" : true, "location-fragments" : [ { "start" : 39, "end" : 235, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-37, "score" : 130.4, "model-ac" : "5fpwA00" }, { "signature" : { "accession" : "PTHR12411:SF356", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 237, "end" : 297, "hmmStart" : 350, "hmmEnd" : 409, "hmmLength" : 413, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 231, "envelopeEnd" : 301, "location-fragments" : [ { "start" : 237, "end" : 297, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-32, "familyName" : "", "score" : 116.4, "model-ac" : "PTHR12411:SF356" }, { "signature" : { "accession" : "G3DSA:3.90.70.10", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 236, "end" : 303, "hmmStart" : 134, "hmmEnd" : 200, "hmmLength" : 205, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.2E-16, "score" : 61.7, "envelopeStart" : 232, "envelopeEnd" : 303, "postProcessed" : true, "location-fragments" : [ { "start" : 236, "end" : 303, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.2E-26, "score" : 93.6, "model-ac" : "1csbB00" } ], "xref" : [ { "name" : "XP_018909834.1 PREDICTED: cathepsin B-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909834.1" } ] },{ "sequence" : "MEGGSDNLSELFTELSLAVDQKSDKVSVILDNLCSKVDKSQIPDEFASDCSSIFSDQLHSLLGWSSSETVTKTADVIASLAKIESTRVALTKPKIAAALLEVLKQNAGLSSDQNYLAMKHASRALGNLCYENNEGRKCVMEHDGLKIILHAIESTINLPDKELCYSLRACVVGLLLNLIMGQTDLYPELIKLGTVELLTKILEAGAEQDETAAIHVLMILSLLAESVNGEPLLTNRLCSVLVKTLGKSTSGELSELCVELIHGQAENNEIRLQLAKCGLCELLIQLMEEHRALVNDDETRNLLKMACDLIIIILNGDDCMRLLYGDGKGKVFLGLTQWLTSTDDDLQITGVLAMGNFARTDNHCAQIVAAGVGKKLISILSKNNTPSGDIRLQHALLSALRNLSIPAQNKPKLIADGIIDVVMPMLNIPTFPVVFKLLGTLRMLVDGQERVACDLGQRKDLLKKLVEWTGTEDHPGVQGEACRLLAWLIKNSRDREVMGRMVAAGAVPCLVGMITAEHTVMQNEALLALCLLSAMRLADAEKSFIQARVGEKINTLVNEMNPPREVFMIVVAMLCQLVNSSELILHLRETGVSKTIGSYASSRENMNDTLDQVASLIALFDPML", "md5" : "f224a4eac251b61060414646e51c5518", "matches" : [ { "signature" : { "accession" : "G3DSA:1.25.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011989", "name" : "ARM-like", "description" : "Armadillo-like helical", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 47, "end" : 327, "hmmStart" : 48, "hmmEnd" : 286, "hmmLength" : 420, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-18, "score" : 69.1, "envelopeStart" : 47, "envelopeEnd" : 327, "postProcessed" : true, "location-fragments" : [ { "start" : 47, "end" : 327, "dc-status" : "CONTINUOUS" } ] }, { "start" : 328, "end" : 606, "hmmStart" : 133, "hmmEnd" : 369, "hmmLength" : 420, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.8E-29, "score" : 103.5, "envelopeStart" : 327, "envelopeEnd" : 606, "postProcessed" : true, "location-fragments" : [ { "start" : 328, "end" : 606, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-48, "score" : 167.8, "model-ac" : "4rv1D00" }, { "signature" : { "accession" : "SSF48371", "name" : "ARM repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016024", "name" : "ARM-type_fold", "description" : "Armadillo-type fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 65, "end" : 491, "hmmLength" : 457, "location-fragments" : [ { "start" : 65, "end" : 491, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.19E-37, "model-ac" : "0051023" }, { "signature" : { "accession" : "SSF48371", "name" : "ARM repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016024", "name" : "ARM-type_fold", "description" : "Armadillo-type fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 459, "end" : 600, "hmmLength" : 264, "location-fragments" : [ { "start" : 459, "end" : 600, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.07E-8, "model-ac" : "0051071" }, { "signature" : { "accession" : "SM00185", "name" : "arm_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000225", "name" : "Armadillo", "description" : "Armadillo", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 406, "end" : 446, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 110.0, "score" : 5.2, "location-fragments" : [ { "start" : 406, "end" : 446, "dc-status" : "CONTINUOUS" } ] }, { "start" : 267, "end" : 315, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 170.0, "score" : 3.8, "location-fragments" : [ { "start" : 267, "end" : 315, "dc-status" : "CONTINUOUS" } ] }, { "start" : 360, "end" : 405, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 0.42, "score" : 19.7, "location-fragments" : [ { "start" : 360, "end" : 405, "dc-status" : "CONTINUOUS" } ] }, { "start" : 182, "end" : 225, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 120.0, "score" : 4.9, "location-fragments" : [ { "start" : 182, "end" : 225, "dc-status" : "CONTINUOUS" } ] }, { "start" : 494, "end" : 534, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 5.8, "score" : 15.1, "location-fragments" : [ { "start" : 494, "end" : 534, "dc-status" : "CONTINUOUS" } ] }, { "start" : 132, "end" : 180, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 380.0, "score" : 1.0, "location-fragments" : [ { "start" : 132, "end" : 180, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-10, "score" : 49.6, "model-ac" : "SM00185" }, { "signature" : { "accession" : "PTHR10957", "name" : "RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR040144", "name" : "RAP1GDS1", "description" : "Rap1 GTPase-GDP dissociation stimulator 1", "type" : "FAMILY", "goXRefs" : [ { "name" : "GTPase activator activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005096" }, { "name" : "positive regulation of GTPase activity", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0043547" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 601, "hmmStart" : 3, "hmmEnd" : 595, "hmmLength" : 616, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 616, "location-fragments" : [ { "start" : 6, "end" : 601, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-129, "familyName" : "RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1", "score" : 436.6, "model-ac" : "PTHR10957" } ], "xref" : [ { "name" : "XP_018909863.1 PREDICTED: rap1 GTPase-GDP dissociation stimulator 1-B isoform X1 [Bemisia tabaci]", "id" : "XP_018909863.1" } ] },{ "sequence" : "MSKVSSEVAVDKVSEVTEKDGNHITAEIKGTKRPADEKTEDVKKQKKEENGEEEELEGEEDVEGEEEDEEDEIAEGEDDLDDAEEEEDEEDADGVDDEEDDA", "md5" : "bd48133750d0d4a7e2016692d289447b", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 52, "end" : 102, "location-fragments" : [ { "start" : 52, "end" : 102, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 102, "location-fragments" : [ { "start" : 1, "end" : 102, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 93, "location-fragments" : [ { "start" : 35, "end" : 93, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 51, "location-fragments" : [ { "start" : 12, "end" : 51, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910192.1 PREDICTED: glutamic acid-rich protein-like [Bemisia tabaci]", "id" : "XP_018910192.1" } ] },{ "sequence" : "MMKHNPDNLYLYLLLVFITSEGIAEDLTGFDFTTLNLSPEHVPYYLHQFPKVAELCSTSDSCPFKDAVGKQLCWGYEDTCVKDQQFSTPVCKGSHKGWVKSKEEQIESFYNQGDFGYVKEQRKEMKVLCDASKQTDSSLECSSYLRFCRGRNIMMNFTHLANRDEPIRYKMDVLHEGQIGGHCRLHEKELKEEVQHVSPLQSWAPELRFFTSLSQPPIESKHCDIVIDKPTVVMKIDATVNMYHHFCDFFNLYASQHVNASHPSMFSNELHVLIWESYQYHSVFSPTWDAFTRYPIWNLKTFKGKTVCFRNIVFPLLPRMIFGLYYNTPLMYGCEKSGLFKAFSQHIVHRLQIPFHPRKNNQVRIAFLSRETTYRKVLNEDALLSSLRKNPRYFVQKVVFTHLTDFKTQLEVIRNSDVLIGMHGAGLTHLLFLPDWAAVFELYNCEDDRCYLDLARLRGLFYLTWQDVKKLKPQDQGHHPDGGAHAKFTNYEFDVPEFIKLVNICAKSVINNKEFQKITSTNHDEL", "md5" : "487b8c3dd47318a73ab3d34d3694bca4", "matches" : [ { "signature" : { "accession" : "PF04577", "name" : "DUF563", "description" : "Protein of unknown function (DUF563)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR007657", "name" : "Glycosyltransferase_61", "description" : "Glycosyltransferase 61", "type" : "FAMILY", "goXRefs" : [ { "name" : "transferase activity, transferring glycosyl groups", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016757" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 241, "end" : 465, "hmmStart" : 1, "hmmEnd" : 205, "hmmLength" : 209, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.8E-23, "score" : 82.1, "envelopeStart" : 241, "envelopeEnd" : 468, "postProcessed" : true, "location-fragments" : [ { "start" : 241, "end" : 465, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-23, "score" : 82.7, "model-ac" : "PF04577" }, { "signature" : { "accession" : "PTHR20961:SF38", "name" : "EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 137, "end" : 495, "hmmStart" : 23, "hmmEnd" : 453, "hmmLength" : 470, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 90, "envelopeEnd" : 511, "location-fragments" : [ { "start" : 137, "end" : 495, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-50, "familyName" : "EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE", "score" : 174.0, "model-ac" : "PTHR20961:SF38" }, { "signature" : { "accession" : "PTHR20961", "name" : "GLYCOSYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR007657", "name" : "Glycosyltransferase_61", "description" : "Glycosyltransferase 61", "type" : "FAMILY", "goXRefs" : [ { "name" : "transferase activity, transferring glycosyl groups", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016757" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 137, "end" : 495, "hmmStart" : 23, "hmmEnd" : 453, "hmmLength" : 470, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 90, "envelopeEnd" : 511, "location-fragments" : [ { "start" : 137, "end" : 495, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-50, "familyName" : "EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE", "score" : 174.0, "model-ac" : "PTHR20961" } ], "xref" : [ { "name" : "XP_018910304.1 PREDICTED: EGF domain-specific O-linked N-acetylglucosamine transferase isoform X1 [Bemisia tabaci]", "id" : "XP_018910304.1" } ] },{ "sequence" : "MGGLFSYFRNLLGGREMRILILGLDGAGKTTILYKLQVGEVVTTIPTIGFNVEQVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSADKDRIGISKDELLYMLREEELQGAILVVLANKQDMDGCMSVTEVYQALGLDALKNRTFQIFKTSAKKGEGLEEAMDWLSNALTSRK", "md5" : "f7dbe68a4aed934632eae3a0347499c7", "matches" : [ { "signature" : { "accession" : "PR00328", "name" : "SAR1GTPBP", "description" : "GTP-binding SAR1 protein signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR006689", "name" : "Small_GTPase_ARF/SAR", "description" : "Small GTPase superfamily, ARF/SAR type", "type" : "FAMILY", "goXRefs" : [ { "name" : "GTP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005525" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 118, "end" : 139, "pvalue" : 0.00569, "score" : 28.07, "motifNumber" : 4, "location-fragments" : [ { "start" : 118, "end" : 139, "dc-status" : "CONTINUOUS" } ] }, { "start" : 18, "end" : 41, "pvalue" : 1.1E-9, "score" : 52.7, "motifNumber" : 1, "location-fragments" : [ { "start" : 18, "end" : 41, "dc-status" : "CONTINUOUS" } ] }, { "start" : 46, "end" : 70, "pvalue" : 1.82E-6, "score" : 36.24, "motifNumber" : 2, "location-fragments" : [ { "start" : 46, "end" : 70, "dc-status" : "CONTINUOUS" } ] }, { "start" : 73, "end" : 98, "pvalue" : 1.35E-9, "score" : 41.18, "motifNumber" : 3, "location-fragments" : [ { "start" : 73, "end" : 98, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-20, "graphscan" : "IIIi.", "model-ac" : "PR00328" }, { "signature" : { "accession" : "TIGR00231", "name" : "TIGR00231", "description" : "small_GTP: small GTP-binding protein domain", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR005225", "name" : "Small_GTP-bd_dom", "description" : "Small GTP-binding protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "GTP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005525" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 15, "end" : 171, "hmmStart" : 2, "hmmEnd" : 161, "hmmLength" : 164, "hmmBounds" : "INCOMPLETE", "evalue" : 4.1E-21, "score" : 73.4, "envelopeStart" : 14, "envelopeEnd" : 174, "postProcessed" : false, "location-fragments" : [ { "start" : 15, "end" : 171, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-21, "score" : 73.6, "model-ac" : "TIGR00231" }, { "signature" : { "accession" : "SM00177", "name" : "arf_sub_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 180, "hmmStart" : 1, "hmmEnd" : 181, "hmmLength" : 181, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-80, "score" : 282.7, "location-fragments" : [ { "start" : 1, "end" : 180, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-80, "score" : 282.7, "model-ac" : "SM00177" }, { "signature" : { "accession" : "PF00025", "name" : "Arf", "description" : "ADP-ribosylation factor family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006689", "name" : "Small_GTPase_ARF/SAR", "description" : "Small GTPase superfamily, ARF/SAR type", "type" : "FAMILY", "goXRefs" : [ { "name" : "GTP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005525" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 175, "hmmStart" : 3, "hmmEnd" : 174, "hmmLength" : 175, "hmmBounds" : "INCOMPLETE", "evalue" : 8.7E-74, "score" : 246.7, "envelopeStart" : 4, "envelopeEnd" : 176, "postProcessed" : true, "location-fragments" : [ { "start" : 6, "end" : 175, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.8E-74, "score" : 246.9, "model-ac" : "PF00025" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 178, "hmmLength" : 224, "location-fragments" : [ { "start" : 13, "end" : 178, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.81E-53, "model-ac" : "0035281" }, { "signature" : { "accession" : "PS51417", "name" : "ARF", "description" : "small GTPase Arf family profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 176, "score" : 22.488, "alignment" : "NLLGGREMRILILGLDGAGKTTILYKLQVGEVVTTIPTIGFNVEQVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSADKDRIGISKDELLYMLREEELQGAILVVLANKQDMDGCMSVTEVYQALGLDAlkNRTF---QIFKTSAKKGEGLEEAMDWLSNAL", "location-fragments" : [ { "start" : 10, "end" : 176, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51417" }, { "signature" : { "accession" : "PTHR11711:SF326", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 178, "hmmStart" : 8, "hmmEnd" : 179, "hmmLength" : 182, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 180, "location-fragments" : [ { "start" : 7, "end" : 178, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-78, "familyName" : "", "score" : 264.0, "model-ac" : "PTHR11711:SF326" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 17, "end" : 176, "hmmStart" : 2, "hmmEnd" : 165, "hmmLength" : 167, "hmmBounds" : "COMPLETE", "evalue" : 3.8E-64, "score" : 217.2, "envelopeStart" : 17, "envelopeEnd" : 176, "postProcessed" : true, "location-fragments" : [ { "start" : 17, "end" : 176, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-64, "score" : 217.4, "model-ac" : "1m2oB00" }, { "signature" : { "accession" : "PTHR11711", "name" : "ADP RIBOSYLATION FACTOR-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 178, "hmmStart" : 8, "hmmEnd" : 179, "hmmLength" : 182, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 180, "location-fragments" : [ { "start" : 7, "end" : 178, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-78, "familyName" : "", "score" : 264.0, "model-ac" : "PTHR11711" }, { "signature" : { "accession" : "SM00175", "name" : "rab_sub_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 17, "end" : 179, "hmmStart" : 1, "hmmEnd" : 172, "hmmLength" : 172, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-5, "score" : -42.3, "location-fragments" : [ { "start" : 17, "end" : 179, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-5, "score" : -42.3, "model-ac" : "SM00175" }, { "signature" : { "accession" : "cd04151", "name" : "Arl1", "description" : "Arl1", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 175, "sites" : [ { "description" : "G2 box", "numLocations" : 1, "siteLocations" : [ { "start" : 47, "end" : 47, "residue" : "T" } ] }, { "description" : "G5 box", "numLocations" : 3, "siteLocations" : [ { "start" : 158, "end" : 158, "residue" : "S" }, { "start" : 160, "end" : 160, "residue" : "K" }, { "start" : 159, "end" : 159, "residue" : "A" } ] }, { "description" : "putative GAP interaction site", "numLocations" : 14, "siteLocations" : [ { "start" : 49, "end" : 49, "residue" : "G" }, { "start" : 25, "end" : 25, "residue" : "D" }, { "start" : 75, "end" : 75, "residue" : "P" }, { "start" : 47, "end" : 47, "residue" : "T" }, { "start" : 53, "end" : 53, "residue" : "E" }, { "start" : 50, "end" : 50, "residue" : "F" }, { "start" : 48, "end" : 48, "residue" : "I" }, { "start" : 30, "end" : 30, "residue" : "T" }, { "start" : 34, "end" : 34, "residue" : "Y" }, { "start" : 46, "end" : 46, "residue" : "P" }, { "start" : 51, "end" : 51, "residue" : "N" }, { "start" : 26, "end" : 26, "residue" : "G" }, { "start" : 52, "end" : 52, "residue" : "V" }, { "start" : 80, "end" : 80, "residue" : "Y" } ] }, { "description" : "G3 box", "numLocations" : 4, "siteLocations" : [ { "start" : 68, "end" : 68, "residue" : "G" }, { "start" : 66, "end" : 66, "residue" : "D" }, { "start" : 67, "end" : 67, "residue" : "L" }, { "start" : 69, "end" : 69, "residue" : "G" } ] }, { "description" : "GTP/Mg2+ binding site", "numLocations" : 16, "siteLocations" : [ { "start" : 27, "end" : 27, "residue" : "A" }, { "start" : 28, "end" : 28, "residue" : "G" }, { "start" : 158, "end" : 158, "residue" : "S" }, { "start" : 25, "end" : 25, "residue" : "D" }, { "start" : 29, "end" : 29, "residue" : "K" }, { "start" : 44, "end" : 44, "residue" : "T" }, { "start" : 31, "end" : 31, "residue" : "T" }, { "start" : 47, "end" : 47, "residue" : "T" }, { "start" : 159, "end" : 159, "residue" : "A" }, { "start" : 69, "end" : 69, "residue" : "G" }, { "start" : 125, "end" : 125, "residue" : "N" }, { "start" : 30, "end" : 30, "residue" : "T" }, { "start" : 26, "end" : 26, "residue" : "G" }, { "start" : 160, "end" : 160, "residue" : "K" }, { "start" : 126, "end" : 126, "residue" : "K" }, { "start" : 128, "end" : 128, "residue" : "D" } ] }, { "description" : "interswitch region", "numLocations" : 14, "siteLocations" : [ { "start" : 62, "end" : 62, "residue" : "F" }, { "start" : 55, "end" : 55, "residue" : "V" }, { "start" : 61, "end" : 61, "residue" : "K" }, { "start" : 53, "end" : 53, "residue" : "E" }, { "start" : 50, "end" : 50, "residue" : "F" }, { "start" : 64, "end" : 64, "residue" : "V" }, { "start" : 57, "end" : 57, "residue" : "Y" }, { "start" : 65, "end" : 65, "residue" : "W" }, { "start" : 51, "end" : 51, "residue" : "N" }, { "start" : 54, "end" : 54, "residue" : "Q" }, { "start" : 52, "end" : 52, "residue" : "V" }, { "start" : 63, "end" : 63, "residue" : "Q" }, { "start" : 60, "end" : 60, "residue" : "L" }, { "start" : 56, "end" : 56, "residue" : "T" } ] }, { "description" : "Switch II region", "numLocations" : 13, "siteLocations" : [ { "start" : 66, "end" : 66, "residue" : "D" }, { "start" : 77, "end" : 77, "residue" : "W" }, { "start" : 67, "end" : 67, "residue" : "L" }, { "start" : 69, "end" : 69, "residue" : "G" }, { "start" : 79, "end" : 79, "residue" : "C" }, { "start" : 74, "end" : 74, "residue" : "R" }, { "start" : 72, "end" : 72, "residue" : "S" }, { "start" : 76, "end" : 76, "residue" : "Y" }, { "start" : 68, "end" : 68, "residue" : "G" }, { "start" : 70, "end" : 70, "residue" : "Q" }, { "start" : 78, "end" : 78, "residue" : "R" }, { "start" : 71, "end" : 71, "residue" : "T" }, { "start" : 73, "end" : 73, "residue" : "I" } ] }, { "description" : "effector interaction site", "numLocations" : 7, "siteLocations" : [ { "start" : 49, "end" : 49, "residue" : "G" }, { "start" : 80, "end" : 80, "residue" : "Y" }, { "start" : 50, "end" : 50, "residue" : "F" }, { "start" : 63, "end" : 63, "residue" : "Q" }, { "start" : 82, "end" : 82, "residue" : "S" }, { "start" : 79, "end" : 79, "residue" : "C" }, { "start" : 114, "end" : 114, "residue" : "E" } ] }, { "description" : "G1 box", "numLocations" : 8, "siteLocations" : [ { "start" : 27, "end" : 27, "residue" : "A" }, { "start" : 28, "end" : 28, "residue" : "G" }, { "start" : 30, "end" : 30, "residue" : "T" }, { "start" : 24, "end" : 24, "residue" : "L" }, { "start" : 26, "end" : 26, "residue" : "G" }, { "start" : 25, "end" : 25, "residue" : "D" }, { "start" : 23, "end" : 23, "residue" : "G" }, { "start" : 29, "end" : 29, "residue" : "K" } ] }, { "description" : "Switch I region", "numLocations" : 16, "siteLocations" : [ { "start" : 38, "end" : 38, "residue" : "V" }, { "start" : 43, "end" : 43, "residue" : "T" }, { "start" : 49, "end" : 49, "residue" : "G" }, { "start" : 45, "end" : 45, "residue" : "I" }, { "start" : 39, "end" : 39, "residue" : "G" }, { "start" : 44, "end" : 44, "residue" : "T" }, { "start" : 42, "end" : 42, "residue" : "V" }, { "start" : 47, "end" : 47, "residue" : "T" }, { "start" : 50, "end" : 50, "residue" : "F" }, { "start" : 48, "end" : 48, "residue" : "I" }, { "start" : 36, "end" : 36, "residue" : "L" }, { "start" : 41, "end" : 41, "residue" : "V" }, { "start" : 46, "end" : 46, "residue" : "P" }, { "start" : 35, "end" : 35, "residue" : "K" }, { "start" : 37, "end" : 37, "residue" : "Q" }, { "start" : 40, "end" : 40, "residue" : "E" } ] }, { "description" : "putative GEF interaction site", "numLocations" : 12, "siteLocations" : [ { "start" : 76, "end" : 76, "residue" : "Y" }, { "start" : 49, "end" : 49, "residue" : "G" }, { "start" : 51, "end" : 51, "residue" : "N" }, { "start" : 70, "end" : 70, "residue" : "Q" }, { "start" : 78, "end" : 78, "residue" : "R" }, { "start" : 66, "end" : 66, "residue" : "D" }, { "start" : 80, "end" : 80, "residue" : "Y" }, { "start" : 47, "end" : 47, "residue" : "T" }, { "start" : 50, "end" : 50, "residue" : "F" }, { "start" : 48, "end" : 48, "residue" : "I" }, { "start" : 79, "end" : 79, "residue" : "C" }, { "start" : 56, "end" : 56, "residue" : "T" } ] }, { "description" : "G4 box", "numLocations" : 4, "siteLocations" : [ { "start" : 125, "end" : 125, "residue" : "N" }, { "start" : 126, "end" : 126, "residue" : "K" }, { "start" : 127, "end" : 127, "residue" : "Q" }, { "start" : 128, "end" : 128, "residue" : "D" } ] } ], "evalue" : 1.71762E-118, "score" : 330.14, "location-fragments" : [ { "start" : 18, "end" : 175, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd04151" }, { "signature" : { "accession" : "SM00178", "name" : "sar_sub_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 176, "hmmStart" : 1, "hmmEnd" : 199, "hmmLength" : 199, "hmmBounds" : "COMPLETE", "evalue" : 4.8E-25, "score" : 99.2, "location-fragments" : [ { "start" : 5, "end" : 176, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-25, "score" : 99.2, "model-ac" : "SM00178" } ], "xref" : [ { "name" : "XP_018909831.1 PREDICTED: ADP-ribosylation factor-like protein 1 [Bemisia tabaci]", "id" : "XP_018909831.1" } ] },{ "sequence" : "MARVFLVLLSAALARAHAVPGDATPAPAPLVTIVNSTNSLSSDSLSSSSSASVSSEDGSRHGKFLISSSGPVSNGIQDKQDLELDDPSLAFNGIYSDCVLQLSFPCFQRKLLVFFDRLGRMKAFNVLGNFLSIVRLKRDLSPAIMEEELKARLASNEVEAQTALGALMEHTLDKFVDNHVLRVNLPFGMTAAMVDENSAERRSSSGNSIDINLGRALGEGRGKKKMKKMMGTMMMMIMGKMALMGPMMMMMIKIKAIKALLLSKLALAMSLLQLFKSMGKGKGGGGGGSGGGKEVIIVHDNHGDSGGGGHGGGGGGYGGSGGGWASGGGGGGGWASGGGGSGWASGGGGHGGGGGDSYAGGVHAGGGDANYAGSDAGHGGGGGGWPAGGGGGGGWGRRSGYDGPPQWMLTYRNNYNQYNGHAQNGAQESEH", "md5" : "c06c04b89155410682cdd67c503acfc4", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 285, "end" : 314, "location-fragments" : [ { "start" : 285, "end" : 314, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR21879", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR012464", "name" : "DUF1676", "description" : "Protein of unknown function DUF1676", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 56, "end" : 398, "hmmStart" : 39, "hmmEnd" : 229, "hmmLength" : 266, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 430, "location-fragments" : [ { "start" : 56, "end" : 398, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-33, "familyName" : "UNCHARACTERIZED", "score" : 117.9, "model-ac" : "PTHR21879" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 382, "end" : 406, "location-fragments" : [ { "start" : 382, "end" : 406, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 412, "end" : 431, "location-fragments" : [ { "start" : 412, "end" : 431, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF07898", "name" : "DUF1676", "description" : "Protein of unknown function (DUF1676)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR012464", "name" : "DUF1676", "description" : "Protein of unknown function DUF1676", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 97, "end" : 276, "hmmStart" : 1, "hmmEnd" : 171, "hmmLength" : 172, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.1E-31, "score" : 110.2, "envelopeStart" : 97, "envelopeEnd" : 277, "postProcessed" : true, "location-fragments" : [ { "start" : 97, "end" : 276, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-32, "score" : 110.6, "model-ac" : "PF07898" } ], "xref" : [ { "name" : "XP_018909939.1 PREDICTED: DEAD-box ATP-dependent RNA helicase rde-12-like [Bemisia tabaci]", "id" : "XP_018909939.1" } ] },{ "sequence" : "MACKSMMQISALRRVPQNKELLQVPQHPLSRPSGLQAAGISALFLCILTFIVVSHDSREYEQNKEVLGWEPYKNRTVAALLAAIDSEEGAEEVLEGPECSSSLLLVVVVHSSPKNEERRMAVRHTWGSANDPSVKVVFLLGKLRNESTEFQERISKEQESFDDIIQENFIDTYHNLTIKSVLMLRWFVQNCRQAKYLFKTDDDMFVDYRVLTKSLREPLPKRIDPGNFLGGVLSQDARPIKNITDKWFMPSYLYAESTYPDYVAGAGYLMSSQVAQKLYKASFEVEMIHMEDVYVTGICAQRAGIEPISLFGFTYAEIKKFNCKTRFFMSHRMTPHEMSDSWTTLTNCSSATFVQSIFQEEECGMWGKFKNLLRRYI", "md5" : "ea80390c7cd054b7fb0a8acec7d19ab1", "matches" : [ { "signature" : { "accession" : "PTHR11214:SF247", "name" : "BETA-1,3-GALACTOSYLTRANSFERASE BRN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 91, "end" : 348, "hmmStart" : 89, "hmmEnd" : 320, "hmmLength" : 325, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 14, "envelopeEnd" : 353, "location-fragments" : [ { "start" : 91, "end" : 348, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-69, "familyName" : "BETA-1,3-GALACTOSYLTRANSFERASE BRN", "score" : 237.7, "model-ac" : "PTHR11214:SF247" }, { "signature" : { "accession" : "PTHR11214", "name" : "BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR002659", "name" : "Glyco_trans_31", "description" : "Glycosyl transferase, family 31", "type" : "FAMILY", "goXRefs" : [ { "name" : "protein glycosylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006486" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 91, "end" : 348, "hmmStart" : 89, "hmmEnd" : 320, "hmmLength" : 325, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 14, "envelopeEnd" : 353, "location-fragments" : [ { "start" : 91, "end" : 348, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-69, "familyName" : "BETA-1,3-GALACTOSYLTRANSFERASE BRN", "score" : 237.7, "model-ac" : "PTHR11214" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 140, "end" : 160, "location-fragments" : [ { "start" : 140, "end" : 160, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF01762", "name" : "Galactosyl_T", "description" : "Galactosyltransferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002659", "name" : "Glyco_trans_31", "description" : "Glycosyl transferase, family 31", "type" : "FAMILY", "goXRefs" : [ { "name" : "protein glycosylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006486" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 117, "end" : 309, "hmmStart" : 1, "hmmEnd" : 193, "hmmLength" : 195, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.8E-47, "score" : 161.7, "envelopeStart" : 117, "envelopeEnd" : 310, "postProcessed" : true, "location-fragments" : [ { "start" : 117, "end" : 309, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-47, "score" : 162.2, "model-ac" : "PF01762" } ], "xref" : [ { "name" : "XP_018910333.1 PREDICTED: beta-1,3-galactosyltransferase 1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910333.1" } ] },{ "sequence" : "MDMIQICSGVLLLILSIAGSVPVPGGDYSHAQYYGYSDEDGDGYEDDGHYDAGHNGYTGHNGYTGHNGGYYQPYQPYVYHGHPGIGYSAQVFGYNGYAHPTYYAPYHDHEHYHYPKYKYEYGVHDPHTGDVKQQYEERDGDVVRGSYSLVEADGTIRVVEYTADDKHGFRAVVKKIGHAVHPPPHPHHHEYSHAPAAYSGYYPAAPVAPVAPVAPVYQYQTPVYHSALPQPIPPQAYSPTAAATPGYPEAFHNAYVVPLQGDAPYQGYGPHAQHFGNDAYTDGLYKKRSPAKNKENQKETQDSQQSVKKETKAESEKESEEAKKKREEEEKKEREARSRKTLLEKQKELKQKLTRQ", "md5" : "dfee8f5c08cbf4d92ebc36077955a999", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 268, "end" : 356, "location-fragments" : [ { "start" : 268, "end" : 356, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00379", "name" : "Chitin_bind_4", "description" : "Insect cuticle protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000618", "name" : "Insect_cuticle", "description" : "Insect cuticle protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of cuticle", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0042302" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 117, "end" : 169, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-13, "score" : 51.0, "envelopeStart" : 117, "envelopeEnd" : 169, "postProcessed" : true, "location-fragments" : [ { "start" : 117, "end" : 169, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-13, "score" : 51.0, "model-ac" : "PF00379" }, { "signature" : { "accession" : "PS00233", "name" : "CHIT_BIND_RR_1", "description" : "Chitin-binding type R&R domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR031311", "name" : "CHIT_BIND_RR_consensus", "description" : "Chitin-binding type R&R consensus", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 145, "end" : 171, "level" : "STRONG", "cigarAlignment" : "1M7I2M6I1M1I2M3I2M1I1M", "alignment" : "GsyslveaDGtirvveYtADdkhGFrA", "location-fragments" : [ { "start" : 145, "end" : 171, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00233" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 308, "end" : 352, "location-fragments" : [ { "start" : 308, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PS51155", "name" : "CHIT_BIND_RR_2", "description" : "Chitin-binding type R&R domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000618", "name" : "Insect_cuticle", "description" : "Insect cuticle protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of cuticle", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0042302" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 114, "end" : 186, "score" : 16.14, "alignment" : "YPKYKYEYGVHDPHTGDVKQQyEERDGD--VVRGSYSLVEADGTIRVVEYTADdKHGFRAVVKkighaVHPPPHP", "location-fragments" : [ { "start" : 114, "end" : 186, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51155" }, { "signature" : { "accession" : "PTHR12236", "name" : "STRUCTURAL CONTITUENT OF CUTICLE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 75, "end" : 194, "hmmStart" : 46, "hmmEnd" : 135, "hmmLength" : 156, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 204, "location-fragments" : [ { "start" : 75, "end" : 194, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-32, "familyName" : "", "score" : 114.0, "model-ac" : "PTHR12236" }, { "signature" : { "accession" : "PR00947", "name" : "CUTICLE", "description" : "Insect cuticle protein signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000618", "name" : "Insect_cuticle", "description" : "Insect cuticle protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of cuticle", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0042302" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 143, "end" : 154, "pvalue" : 1.94E-6, "score" : 53.42, "motifNumber" : 2, "location-fragments" : [ { "start" : 143, "end" : 154, "dc-status" : "CONTINUOUS" } ] }, { "start" : 154, "end" : 165, "pvalue" : 3.53E-5, "score" : 48.63, "motifNumber" : 3, "location-fragments" : [ { "start" : 154, "end" : 165, "dc-status" : "CONTINUOUS" } ] }, { "start" : 115, "end" : 126, "pvalue" : 0.00145, "score" : 29.37, "motifNumber" : 1, "location-fragments" : [ { "start" : 115, "end" : 126, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-7, "graphscan" : "iII", "model-ac" : "PR00947" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 285, "end" : 356, "location-fragments" : [ { "start" : 285, "end" : 356, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12236:SF48", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 75, "end" : 194, "hmmStart" : 46, "hmmEnd" : 135, "hmmLength" : 156, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 204, "location-fragments" : [ { "start" : 75, "end" : 194, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-32, "familyName" : "", "score" : 114.0, "model-ac" : "PTHR12236:SF48" } ], "xref" : [ { "name" : "XP_018910373.1 PREDICTED: uncharacterized protein LOC109039368 [Bemisia tabaci]", "id" : "XP_018910373.1" } ] },{ "sequence" : "MAWKVVIFTDENKVREVPVGWVNEEVKTCVWPSIRTESKVTKYIEECRPPSEKWRCFNVRILAKGKIFSTHQEAKLAALLAEDLTDIESEAETTFSQDSQQKQTTEQNSQEKDDSSGSSCKDKDADSHKDSCEDKE", "md5" : "42e73e86a78518ab274e55f3fd70455a", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 90, "end" : 114, "location-fragments" : [ { "start" : 90, "end" : 114, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 90, "end" : 136, "location-fragments" : [ { "start" : 90, "end" : 136, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 115, "end" : 136, "location-fragments" : [ { "start" : 115, "end" : 136, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910415.1 PREDICTED: uncharacterized protein LOC109039401, partial [Bemisia tabaci]", "id" : "XP_018910415.1" } ] },{ "sequence" : "MPETLKYEKIESDTECGKVLNTLFVNKFRRGYVRVKGAVMPEDFKKFGDRIQQMDIRDDDVFVCSFPKAGTTWAQEMVWCIANNLDYKGAEVVLPERFPFLDYSIIYNHEVMYEEDPDFSAPDYVMQSVKYVNELNTRRFIKTHLPFRLLPEKLQNFSTQAKIIYMCRNPKDACVSYYRYYQLIGDYTGDFDTLCNSFRNDMLPYSPFWQHVLEYWAQRNNPCVLFLRYEEMKKDLPSVIRRTATFLGKSLSEEELPRLAQHLSFESMKGNRAVNYKPQIQINKKYNLSERDGTTMPSGSVGGWKKLMTPQTVKEFDAWSEAKVNGSGFKLVC", "md5" : "57821c2ad4609474c43978ab5f2bbc4b", "matches" : [ { "signature" : { "accession" : "PTHR11783", "name" : "SULFOTRANSFERASE SULT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 330, "hmmStart" : 13, "hmmEnd" : 322, "hmmLength" : 326, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 333, "location-fragments" : [ { "start" : 18, "end" : 330, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-107, "familyName" : "MIP25022P1", "score" : 359.9, "model-ac" : "PTHR11783" }, { "signature" : { "accession" : "PF00685", "name" : "Sulfotransfer_1", "description" : "Sulfotransferase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000863", "name" : "Sulfotransferase_dom", "description" : "Sulfotransferase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "sulfotransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008146" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 58, "end" : 327, "hmmStart" : 1, "hmmEnd" : 266, "hmmLength" : 267, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.2E-61, "score" : 208.5, "envelopeStart" : 58, "envelopeEnd" : 328, "postProcessed" : true, "location-fragments" : [ { "start" : 58, "end" : 327, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-61, "score" : 208.8, "model-ac" : "PF00685" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 331, "hmmStart" : 38, "hmmEnd" : 345, "hmmLength" : 351, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-96, "score" : 323.9, "envelopeStart" : 5, "envelopeEnd" : 331, "postProcessed" : true, "location-fragments" : [ { "start" : 5, "end" : 331, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-96, "score" : 324.3, "model-ac" : "1fmjA00" }, { "signature" : { "accession" : "PTHR11783:SF154", "name" : "MIP25022P1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 330, "hmmStart" : 13, "hmmEnd" : 322, "hmmLength" : 326, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 333, "location-fragments" : [ { "start" : 18, "end" : 330, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-107, "familyName" : "MIP25022P1", "score" : 359.9, "model-ac" : "PTHR11783:SF154" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 29, "end" : 331, "hmmLength" : 293, "location-fragments" : [ { "start" : 29, "end" : 331, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.49E-79, "model-ac" : "0051116" } ], "xref" : [ { "name" : "XP_018909820.1 PREDICTED: estrogen sulfotransferase-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909820.1" }, { "name" : "XP_018909818.1 PREDICTED: estrogen sulfotransferase-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909818.1" }, { "name" : "XP_018909817.1 PREDICTED: estrogen sulfotransferase-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909817.1" }, { "name" : "XP_018909819.1 PREDICTED: estrogen sulfotransferase-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909819.1" }, { "name" : "XP_018909821.1 PREDICTED: estrogen sulfotransferase-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909821.1" } ] },{ "sequence" : "MRALRDRIQSNVVERNPNVRKIFQTKVKQTPSNDNAEKLKVMADYIEQDGCEKANEIDISADEECRIIISHRSTSVDEHLEKKIKQTLKEDVLEESKTRLQWRLHFLCGKQAVVDHLLSKVKKRYENIMKNEQYRKSILAKLMLQAALKILEPTVFLRVQEEDFGLAQQLIPCVQENYSKVTGLSMTIILDKLYPLPTETGGGVQLRTPDNRIFVNNLVTRRIELCIASVHPLIRTVLFDDVIHPLMSEGQIILDHDRLSEFSECSL", "md5" : "29c56f36c20c46537861a5288c88f1b0", "matches" : [ { "signature" : { "accession" : "PF01991", "name" : "vATP-synt_E", "description" : "ATP synthase (E/31 kDa) subunit", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002842", "name" : "ATPase_V1_Esu", "description" : "V-type ATPase subunit E", "type" : "FAMILY", "goXRefs" : [ { "name" : "proton-transporting two-sector ATPase complex, catalytic domain", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0033178" }, { "name" : "proton transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:1902600" }, { "name" : "proton-transporting ATPase activity, rotational mechanism", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046961" } ], "pathwayXRefs" : [ { "name" : "Ion channel transport", "databaseName" : "Reactome", "id" : "R-HSA-983712" }, { "name" : "ROS and RNS production in phagocytes", "databaseName" : "Reactome", "id" : "R-HSA-1222556" }, { "name" : "Transferrin endocytosis and recycling", "databaseName" : "Reactome", "id" : "R-HSA-917977" }, { "name" : "Amino acids regulate mTORC1", "databaseName" : "Reactome", "id" : "R-HSA-9639288" }, { "name" : "Insulin receptor recycling", "databaseName" : "Reactome", "id" : "R-HSA-77387" } ] } }, "locations" : [ { "start" : 46, "end" : 239, "hmmStart" : 2, "hmmEnd" : 199, "hmmLength" : 199, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 6.7E-32, "score" : 110.5, "envelopeStart" : 45, "envelopeEnd" : 239, "postProcessed" : true, "location-fragments" : [ { "start" : 46, "end" : 239, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-32, "score" : 110.9, "model-ac" : "PF01991" }, { "signature" : { "accession" : "SSF160527", "name" : "V-type ATPase subunit E-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 113, "end" : 240, "hmmLength" : 118, "location-fragments" : [ { "start" : 113, "end" : 240, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.89E-17, "model-ac" : "0053834" }, { "signature" : { "accession" : "PTHR45715:SF3", "name" : "ATPASE H+-TRANSPORTING V1 SUBUNIT E1B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 33, "end" : 240, "hmmStart" : 6, "hmmEnd" : 217, "hmmLength" : 219, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 27, "envelopeEnd" : 242, "location-fragments" : [ { "start" : 33, "end" : 240, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-38, "familyName" : "ATPASE H+-TRANSPORTING V1 SUBUNIT E1B", "score" : 134.1, "model-ac" : "PTHR45715:SF3" }, { "signature" : { "accession" : "G3DSA:3.30.2320.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR038495", "name" : "ATPase_E_C", "description" : "V-type ATPase subunit E, C-terminal domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Transferrin endocytosis and recycling", "databaseName" : "Reactome", "id" : "R-HSA-917977" }, { "name" : "Amino acids regulate mTORC1", "databaseName" : "Reactome", "id" : "R-HSA-9639288" }, { "name" : "Insulin receptor recycling", "databaseName" : "Reactome", "id" : "R-HSA-77387" }, { "name" : "Ion channel transport", "databaseName" : "Reactome", "id" : "R-HSA-983712" }, { "name" : "ROS and RNS production in phagocytes", "databaseName" : "Reactome", "id" : "R-HSA-1222556" } ] } }, "locations" : [ { "start" : 116, "end" : 244, "hmmStart" : 3, "hmmEnd" : 127, "hmmLength" : 136, "hmmBounds" : "COMPLETE", "evalue" : 5.9E-24, "score" : 86.1, "envelopeStart" : 116, "envelopeEnd" : 244, "postProcessed" : true, "location-fragments" : [ { "start" : 116, "end" : 244, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-24, "score" : 86.1, "model-ac" : "4efaE02" }, { "signature" : { "accession" : "PTHR45715", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 33, "end" : 240, "hmmStart" : 6, "hmmEnd" : 217, "hmmLength" : 219, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 27, "envelopeEnd" : 242, "location-fragments" : [ { "start" : 33, "end" : 240, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-38, "familyName" : "ATPASE H+-TRANSPORTING V1 SUBUNIT E1B", "score" : 134.1, "model-ac" : "PTHR45715" } ], "xref" : [ { "name" : "XP_018910138.1 PREDICTED: V-type proton ATPase subunit E 2-like [Bemisia tabaci]", "id" : "XP_018910138.1" } ] },{ "sequence" : "MLRMHLNMGAAGFAVNFRNIIVREWMVLLVFACFRELSGGLAMPDDLPKLLGSAGHPTAELPPLNFPEPSDEGFRAAGNGLESPHKALRAPVLSPLTEILRARGSEARLNDTLARFPMQDILFRLNNLTGTPESRHQDYAIQSSSRLVSSLSRTDSMRPRAGAVIEEKDEGMETAELSAKIQATLAKEEDQLIVEPTKSAAGFVLVVVVVSVASYVALFVWRKILEQRYGNREMLIDDDQFCHASNLYDFQLGSENEMS", "md5" : "0937812240af22517c8dabf4ef58e471", "matches" : [ ], "xref" : [ { "name" : "XP_018910203.1 PREDICTED: uncharacterized protein LOC109039248 [Bemisia tabaci]", "id" : "XP_018910203.1" } ] },{ "sequence" : "MSTAAVAENSWLGPCEQQDSLWDKMSGASAVAGGLKKRNQERKKPDPKPQSQINKCLNEKRRREQENIYIEELAELIHALPDMSSLAVNKPDKCAILQETVNQIRHIKQQEASGSSDAVQQGEVSSSKPTLLANNIFGPLLLEALEGFYFIVNQDGKIECVSENVHQFIRFTRDELIGKSIYNFIHLGDHARFSSCLLPMSVGWSPLDRSSVDPLTTRKKIFNCRLLIGPSAGREETMEEKQQRIEKYETMQISSAQVPYPGEKSNGDTSTSSGGEVSSECADVGPCLLCVARRIPPNEKPMGTPTEQFTMKLDPSGKIVGVDTSCVSSTYSQYLNKDLTGRLVQELCHDQDFIKLDSHLKETLTTGCCMSAIYRLRLAAEKYVHVQTKSKYFKATGIDPDFIMATHSIISDNDVPATSDSSISGPSLSTSSVGGPLMPIVNGNLQGPPNSRRSTNESCNTITLNSNSAYHTFTLNNDISMSDLNDLFPTSTCSWDLNMPSNEERPSWDGPESRQSLTPAQSPLNPYSQATQPSPATNPPTTPFSNSFVFSPLPVLDEPKEQKEPLESASENGESARLRNLLTNKRSSTDSEDSQAAGRNKDRILKKLLDQEKEEGSENISVKIEEGMSGLVRRHSMGTPHTTPTHPPPDTPPAQQNKPSSGNNNMLLQLLNERKDDDDVEARAGLKKQNELLQHLFKEEDSSKHNSTDDNLNRGQSRKRPSEEGEDTGGQSAKKVSNPISNPVSILETLPPPPPPGSSASQQPNSKLWERNKMLASLLAEKPNTPTHIPPIPPSVISATPQDNIPRVNKVPAAWSGGSLQRQNAHGGLRNGPRPGTAPTRPQQPQQHNYMIENDQQPPRQWDNSNGPSWDSHQLSDPVLSDILDQVIDIVPDAIITDSSAIMNLLDVIESPNSLGYQFNTPNDKTAAIDAIQKSLMLCESTIKNSSYNNQLSAGQNSIQSAQAQQHQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQNYPPPPVYQQRPRFISQAPLGQRPPFTGANSHLAQQQLVIQQRSKLLQQQQQQQQKQRLLQQQQQQSLLIPSNAAATPQELQNIDSLMNNSVAPNVSLQRSSSVPDSQLSPSSYGNALLNSAPSQISPSQRAPPYSPLSHQQQTFSPVNGGVNSFPAVSSAAQQTGARLSPSGLSPFQQQLSPRVSQAGQVQVQVQAQTQVGQGNYPVMNSLSPGQQASGQWSPQSSNNSNRLTLQQQQNPMLNAQLTAGNTYNNTRAAFVQQRLVPQHQQQQQQLPSVRSLPSPSARASPFSSDSPSYQQNPNQQQQYRLQRTISAPPPLNTTPTHTTHLPGGNNGASEYVRQELRAVVGARQGGLRPSPQIQIAPGQVTSADLEALGLSYEMPSSGGNVSPKLWANMSSELAASSGQPGLPRPGMEDVGVRQGAEKSSLLQKLLSE", "md5" : "1a26487addbe5b764468bd02594e0cae", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1202, "end" : 1335, "location-fragments" : [ { "start" : 1202, "end" : 1335, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1397, "end" : 1435, "location-fragments" : [ { "start" : 1397, "end" : 1435, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.450.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 303, "end" : 412, "hmmStart" : 5, "hmmEnd" : 112, "hmmLength" : 114, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-37, "score" : 130.5, "envelopeStart" : 303, "envelopeEnd" : 412, "postProcessed" : true, "location-fragments" : [ { "start" : 303, "end" : 412, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-38, "score" : 133.8, "model-ac" : "1oj5A00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 573, "end" : 594, "location-fragments" : [ { "start" : 573, "end" : 594, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50112", "name" : "PAS", "description" : "PAS repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 141, "end" : 186, "score" : 12.357, "alignment" : "-------LLEALEGFYFIVNQDGKIECVSENVHQFIRFTRDELIGKS-IYNFIH------------------", "location-fragments" : [ { "start" : 141, "end" : 186, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50112" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 841, "end" : 874, "location-fragments" : [ { "start" : 841, "end" : 874, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 498, "end" : 874, "location-fragments" : [ { "start" : 498, "end" : 874, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50888", "name" : "BHLH", "description" : "Myc-type, basic helix-loop-helix (bHLH) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR011598", "name" : "bHLH_dom", "description" : "Myc-type, basic helix-loop-helix (bHLH) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 107, "score" : 12.9, "alignment" : "QSQINKCLNEKRRREQENIYIEELAELIHALPDMsslavNKPDKCAILQETVNQIRHI", "location-fragments" : [ { "start" : 50, "end" : 107, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50888" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1043, "end" : 1063, "location-fragments" : [ { "start" : 1043, "end" : 1063, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 962, "end" : 998, "location-fragments" : [ { "start" : 962, "end" : 998, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF14598", "name" : "PAS_11", "description" : "PAS domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 306, "end" : 414, "hmmStart" : 1, "hmmEnd" : 112, "hmmLength" : 113, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.7E-31, "score" : 108.0, "envelopeStart" : 306, "envelopeEnd" : 415, "postProcessed" : true, "location-fragments" : [ { "start" : 306, "end" : 414, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-31, "score" : 108.0, "model-ac" : "PF14598" }, { "signature" : { "accession" : "SSF47459", "name" : "HLH, helix-loop-helix DNA-binding domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036638", "name" : "HLH_DNA-bd_sf", "description" : "Helix-loop-helix DNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 47, "end" : 115, "hmmLength" : 80, "location-fragments" : [ { "start" : 47, "end" : 115, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.54E-9, "model-ac" : "0035101" }, { "signature" : { "accession" : "SM00353", "name" : "finulus", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR011598", "name" : "bHLH_dom", "description" : "Myc-type, basic helix-loop-helix (bHLH) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 56, "end" : 113, "hmmStart" : 1, "hmmEnd" : 61, "hmmLength" : 61, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-9, "score" : 47.0, "location-fragments" : [ { "start" : 56, "end" : 113, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-9, "score" : 47.0, "model-ac" : "SM00353" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 420, "end" : 460, "location-fragments" : [ { "start" : 420, "end" : 460, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1202, "end" : 1332, "location-fragments" : [ { "start" : 1202, "end" : 1332, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 17, "end" : 52, "location-fragments" : [ { "start" : 17, "end" : 52, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 731, "end" : 745, "location-fragments" : [ { "start" : 731, "end" : 745, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1094, "end" : 1182, "location-fragments" : [ { "start" : 1094, "end" : 1182, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 656, "end" : 670, "location-fragments" : [ { "start" : 656, "end" : 670, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00010", "name" : "HLH", "description" : "Helix-loop-helix DNA-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR011598", "name" : "bHLH_dom", "description" : "Myc-type, basic helix-loop-helix (bHLH) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 54, "end" : 107, "hmmStart" : 4, "hmmEnd" : 53, "hmmLength" : 54, "hmmBounds" : "INCOMPLETE", "evalue" : 3.8E-5, "score" : 23.6, "envelopeStart" : 51, "envelopeEnd" : 108, "postProcessed" : true, "location-fragments" : [ { "start" : 54, "end" : 107, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-5, "score" : 25.0, "model-ac" : "PF00010" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 671, "end" : 730, "location-fragments" : [ { "start" : 671, "end" : 730, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00091", "name" : "pas_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 136, "end" : 202, "hmmStart" : 1, "hmmEnd" : 68, "hmmLength" : 68, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-6, "score" : 38.0, "location-fragments" : [ { "start" : 136, "end" : 202, "dc-status" : "CONTINUOUS" } ] }, { "start" : 296, "end" : 365, "hmmStart" : 1, "hmmEnd" : 68, "hmmLength" : 68, "hmmBounds" : "COMPLETE", "evalue" : 74.0, "score" : 4.8, "location-fragments" : [ { "start" : 296, "end" : 365, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-8, "score" : 42.8, "model-ac" : "SM00091" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 444, "end" : 460, "location-fragments" : [ { "start" : 444, "end" : 460, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 746, "end" : 760, "location-fragments" : [ { "start" : 746, "end" : 760, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00130", "name" : "PAS", "description" : "PAS", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 309, "end" : 388, "sites" : [ { "description" : "putative active site", "numLocations" : 9, "siteLocations" : [ { "start" : 350, "end" : 350, "residue" : "D" }, { "start" : 326, "end" : 326, "residue" : "C" }, { "start" : 348, "end" : 348, "residue" : "C" }, { "start" : 376, "end" : 376, "residue" : "L" }, { "start" : 322, "end" : 322, "residue" : "V" }, { "start" : 347, "end" : 347, "residue" : "L" }, { "start" : 381, "end" : 381, "residue" : "E" }, { "start" : 349, "end" : 349, "residue" : "H" }, { "start" : 334, "end" : 334, "residue" : "Y" } ] }, { "description" : "heme pocket", "numLocations" : 6, "siteLocations" : [ { "start" : 348, "end" : 348, "residue" : "C" }, { "start" : 359, "end" : 359, "residue" : "H" }, { "start" : 360, "end" : 360, "residue" : "L" }, { "start" : 388, "end" : 388, "residue" : "T" }, { "start" : 344, "end" : 344, "residue" : "V" }, { "start" : 356, "end" : 356, "residue" : "L" } ] } ], "evalue" : 9.46916E-4, "score" : 37.998, "location-fragments" : [ { "start" : 309, "end" : 388, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00130" }, { "signature" : { "accession" : "SSF55785", "name" : "PYP-like sensor domain (PAS domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035965", "name" : "PAS-like_dom_sf", "description" : "PAS domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 145, "end" : 196, "hmmLength" : 109, "location-fragments" : [ { "start" : 145, "end" : 196, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.77E-11, "model-ac" : "0048579" }, { "signature" : { "accession" : "PTHR10684:SF4", "name" : "TAIMAN, ISOFORM G", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 38, "end" : 466, "hmmStart" : 4, "hmmEnd" : 398, "hmmLength" : 1664, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 25, "envelopeEnd" : 487, "location-fragments" : [ { "start" : 38, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-154, "familyName" : "TAIMAN, ISOFORM G", "score" : 518.4, "model-ac" : "PTHR10684:SF4" }, { "signature" : { "accession" : "cd00083", "name" : "HLH", "description" : "HLH", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR011598", "name" : "bHLH_dom", "description" : "Myc-type, basic helix-loop-helix (bHLH) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 48, "end" : 112, "sites" : [ { "description" : "E-box/N-box specificity site", "numLocations" : 1, "siteLocations" : [ { "start" : 59, "end" : 59, "residue" : "E" } ] }, { "description" : "dimerization interface", "numLocations" : 14, "siteLocations" : [ { "start" : 110, "end" : 110, "residue" : "Q" }, { "start" : 69, "end" : 69, "residue" : "Y" }, { "start" : 103, "end" : 103, "residue" : "Q" }, { "start" : 101, "end" : 101, "residue" : "V" }, { "start" : 108, "end" : 108, "residue" : "K" }, { "start" : 73, "end" : 73, "residue" : "L" }, { "start" : 70, "end" : 70, "residue" : "I" }, { "start" : 94, "end" : 94, "residue" : "C" }, { "start" : 111, "end" : 111, "residue" : "E" }, { "start" : 65, "end" : 65, "residue" : "Q" }, { "start" : 66, "end" : 66, "residue" : "E" }, { "start" : 104, "end" : 104, "residue" : "I" }, { "start" : 97, "end" : 97, "residue" : "L" }, { "start" : 72, "end" : 72, "residue" : "E" } ] }, { "description" : "DNA binding region", "numLocations" : 8, "siteLocations" : [ { "start" : 51, "end" : 51, "residue" : "S" }, { "start" : 90, "end" : 90, "residue" : "K" }, { "start" : 58, "end" : 58, "residue" : "N" }, { "start" : 62, "end" : 62, "residue" : "R" }, { "start" : 93, "end" : 93, "residue" : "K" }, { "start" : 52, "end" : 52, "residue" : "Q" }, { "start" : 59, "end" : 59, "residue" : "E" }, { "start" : 60, "end" : 60, "residue" : "K" } ] } ], "evalue" : 3.93892E-8, "score" : 49.1347, "location-fragments" : [ { "start" : 48, "end" : 112, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00083" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 256, "end" : 275, "location-fragments" : [ { "start" : 256, "end" : 275, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 420, "end" : 437, "location-fragments" : [ { "start" : 420, "end" : 437, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 991, "end" : 1029, "location-fragments" : [ { "start" : 991, "end" : 1029, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 595, "end" : 621, "location-fragments" : [ { "start" : 595, "end" : 621, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 36, "end" : 52, "location-fragments" : [ { "start" : 36, "end" : 52, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:4.10.280.10", "name" : "HLH", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036638", "name" : "HLH_DNA-bd_sf", "description" : "Helix-loop-helix DNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 58, "end" : 145, "hmmStart" : 2, "hmmEnd" : 77, "hmmLength" : 77, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-22, "score" : 80.3, "envelopeStart" : 58, "envelopeEnd" : 145, "postProcessed" : true, "location-fragments" : [ { "start" : 58, "end" : 145, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-22, "score" : 80.3, "model-ac" : "4f3lA01" }, { "signature" : { "accession" : "G3DSA:3.30.450.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 146, "end" : 295, "hmmStart" : 1, "hmmEnd" : 111, "hmmLength" : 144, "hmmBounds" : "COMPLETE", "evalue" : 8.7E-18, "score" : 66.7, "envelopeStart" : 146, "envelopeEnd" : 295, "postProcessed" : true, "location-fragments" : [ { "start" : 146, "end" : 295, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-20, "score" : 74.8, "model-ac" : "4f3lA02" }, { "signature" : { "accession" : "cd00130", "name" : "PAS", "description" : "PAS", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 147, "end" : 197, "sites" : [ ], "evalue" : 1.5054E-7, "score" : 48.7835, "location-fragments" : [ { "start" : 147, "end" : 197, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00130" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 511, "end" : 549, "location-fragments" : [ { "start" : 511, "end" : 549, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF55785", "name" : "PYP-like sensor domain (PAS domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035965", "name" : "PAS-like_dom_sf", "description" : "PAS domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 307, "end" : 412, "hmmLength" : 109, "location-fragments" : [ { "start" : 307, "end" : 412, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.22E-9, "model-ac" : "0048579" }, { "signature" : { "accession" : "PTHR10684", "name" : "NUCLEAR RECEPTOR COACTIVATOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR017426", "name" : "Nuclear_rcpt_coactivator", "description" : "Nuclear receptor coactivator", "type" : "FAMILY", "goXRefs" : [ { "name" : "nuclear receptor transcription coactivator activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030374" }, { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" }, { "name" : "regulation of transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006355" } ], "pathwayXRefs" : [ { "name" : "PPARA activates gene expression", "databaseName" : "Reactome", "id" : "R-HSA-1989781" }, { "name" : "Estrogen-dependent gene expression", "databaseName" : "Reactome", "id" : "R-HSA-9018519" }, { "name" : "Transcriptional regulation of white adipocyte differentiation", "databaseName" : "Reactome", "id" : "R-HSA-381340" } ] } }, "locations" : [ { "start" : 38, "end" : 466, "hmmStart" : 4, "hmmEnd" : 398, "hmmLength" : 1664, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 25, "envelopeEnd" : 487, "location-fragments" : [ { "start" : 38, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-154, "familyName" : "TAIMAN, ISOFORM G", "score" : 518.4, "model-ac" : "PTHR10684" } ], "xref" : [ { "name" : "XP_018909636.1 PREDICTED: nuclear receptor coactivator 2-like isoform X3 [Bemisia tabaci]", "id" : "XP_018909636.1" } ] },{ "sequence" : "MEGLSETQCKVCGDKASGKHYGVASCDGCRGFFKRSIRRNLEYVCKENGKCIVDVTRRNQCQACRFSKCLLVNMKKDAVQHERTSRQNSHHHHHRFHRSRELCSPIFPSAFIYRYPHPFPYSVAAIMSKSELHQTTPASRPLGAFNNYLALHDCQYISVSKDCQQLLKEDEVSSSEEVQHITPQDVTKSSPISPKKERQDDVSVDMPNEGIYESAAKLLFLAVKWARSIPSFIQLPSHDQSLLLEDSWSELFALSAAQWSFALDQGFLVINSAAPEYRHSALEETVRKLKGIVNRILTMRLDHTEFTCLKALVLFKSDVAGLSEPSYIELLQDQTQVMLREYISVTSKVRFGKLLLLLPVLASLEKRNLEELFFRKTIGNVSISSLLTDMLQQ", "md5" : "cb0fc5ed6ae8a1d4803cf176688e146e", "matches" : [ { "signature" : { "accession" : "G3DSA:3.30.50.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013088", "name" : "Znf_NHR/GATA", "description" : "Zinc finger, NHR/GATA-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" }, { "name" : "regulation of transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006355" } ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 2, "end" : 104, "hmmStart" : 9, "hmmEnd" : 95, "hmmLength" : 113, "hmmBounds" : "COMPLETE", "evalue" : 3.1E-33, "score" : 116.0, "envelopeStart" : 2, "envelopeEnd" : 104, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 104, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-33, "score" : 117.1, "model-ac" : "2a66A00" }, { "signature" : { "accession" : "PTHR24083:SF87", "name" : "NUCLEAR HORMONE RECEPTOR FAMILY", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 378, "hmmStart" : 26, "hmmEnd" : 346, "hmmLength" : 346, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 378, "location-fragments" : [ { "start" : 5, "end" : 378, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-113, "familyName" : "NUCLEAR HORMONE RECEPTOR FAMILY", "score" : 382.0, "model-ac" : "PTHR24083:SF87" }, { "signature" : { "accession" : "PS00031", "name" : "NUCLEAR_REC_DBD_1", "description" : "Nuclear hormones receptors DNA-binding region signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR001628", "name" : "Znf_hrmn_rcpt", "description" : "Zinc finger, nuclear hormone receptor-type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "sequence-specific DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0043565" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" }, { "name" : "regulation of transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006355" }, { "name" : "DNA-binding transcription factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003700" } ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 9, "end" : 35, "level" : "STRONG", "cigarAlignment" : "1M2I1M1I1M5I2M4I1M2I1M2I2M1I1M", "alignment" : "CkvCgDkasgkHYgvasCdgCrgFFkR", "location-fragments" : [ { "start" : 9, "end" : 35, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00031" }, { "signature" : { "accession" : "SM00399", "name" : "c4gold", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001628", "name" : "Znf_hrmn_rcpt", "description" : "Zinc finger, nuclear hormone receptor-type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "sequence-specific DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0043565" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" }, { "name" : "regulation of transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006355" }, { "name" : "DNA-binding transcription factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003700" } ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 6, "end" : 77, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 72, "hmmBounds" : "COMPLETE", "evalue" : 7.1E-33, "score" : 125.2, "location-fragments" : [ { "start" : 6, "end" : 77, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.1E-33, "score" : 125.2, "model-ac" : "SM00399" }, { "signature" : { "accession" : "PF00105", "name" : "zf-C4", "description" : "Zinc finger, C4 type (two domains)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001628", "name" : "Znf_hrmn_rcpt", "description" : "Zinc finger, nuclear hormone receptor-type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "sequence-specific DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0043565" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" }, { "name" : "regulation of transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006355" }, { "name" : "DNA-binding transcription factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003700" } ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 8, "end" : 76, "hmmStart" : 2, "hmmEnd" : 70, "hmmLength" : 70, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.8E-29, "score" : 100.6, "envelopeStart" : 7, "envelopeEnd" : 76, "postProcessed" : true, "location-fragments" : [ { "start" : 8, "end" : 76, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-29, "score" : 101.6, "model-ac" : "PF00105" }, { "signature" : { "accession" : "G3DSA:1.10.565.10", "name" : "Retinoid X Receptor", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR035500", "name" : "NHR-like_dom_sf", "description" : "Nuclear hormone receptor-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 161, "end" : 393, "hmmStart" : 34, "hmmEnd" : 234, "hmmLength" : 249, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-64, "score" : 218.2, "envelopeStart" : 161, "envelopeEnd" : 393, "postProcessed" : true, "location-fragments" : [ { "start" : 161, "end" : 393, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-64, "score" : 218.6, "model-ac" : "3p0uA00" }, { "signature" : { "accession" : "PS51030", "name" : "NUCLEAR_REC_DBD_2", "description" : "Nuclear hormone receptors DNA-binding domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001628", "name" : "Znf_hrmn_rcpt", "description" : "Zinc finger, nuclear hormone receptor-type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "sequence-specific DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0043565" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" }, { "name" : "regulation of transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006355" }, { "name" : "DNA-binding transcription factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003700" } ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 6, "end" : 81, "score" : 20.156, "alignment" : "ETQCKVCGDKASGKHYGVASCDGCRGFFKRSIRRNLEYVCKENGKCIVDVTRRNQCQACRFSKCLLVNMKKDAVQH", "location-fragments" : [ { "start" : 6, "end" : 81, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51030" }, { "signature" : { "accession" : "cd07164", "name" : "NR_DBD_PNR_like_1", "description" : "NR_DBD_PNR_like_1", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 86, "sites" : [ { "description" : "putative DNA binding site", "numLocations" : 15, "siteLocations" : [ { "start" : 20, "end" : 20, "residue" : "H" }, { "start" : 28, "end" : 28, "residue" : "G" }, { "start" : 59, "end" : 59, "residue" : "N" }, { "start" : 62, "end" : 62, "residue" : "Q" }, { "start" : 38, "end" : 38, "residue" : "R" }, { "start" : 21, "end" : 21, "residue" : "Y" }, { "start" : 65, "end" : 65, "residue" : "R" }, { "start" : 58, "end" : 58, "residue" : "R" }, { "start" : 76, "end" : 76, "residue" : "K" }, { "start" : 27, "end" : 27, "residue" : "D" }, { "start" : 35, "end" : 35, "residue" : "R" }, { "start" : 30, "end" : 30, "residue" : "R" }, { "start" : 79, "end" : 79, "residue" : "V" }, { "start" : 19, "end" : 19, "residue" : "K" }, { "start" : 32, "end" : 32, "residue" : "F" } ] }, { "description" : "zinc binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 51, "end" : 51, "residue" : "C" }, { "start" : 12, "end" : 12, "residue" : "C" }, { "start" : 9, "end" : 9, "residue" : "C" }, { "start" : 26, "end" : 26, "residue" : "C" }, { "start" : 64, "end" : 64, "residue" : "C" }, { "start" : 29, "end" : 29, "residue" : "C" }, { "start" : 45, "end" : 45, "residue" : "C" }, { "start" : 61, "end" : 61, "residue" : "C" } ] } ], "evalue" : 1.96912E-53, "score" : 169.952, "location-fragments" : [ { "start" : 9, "end" : 86, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd07164" }, { "signature" : { "accession" : "SSF57716", "name" : "Glucocorticoid receptor-like (DNA-binding domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 92, "hmmLength" : 96, "location-fragments" : [ { "start" : 7, "end" : 92, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.63E-28, "model-ac" : "0053658" }, { "signature" : { "accession" : "SM00430", "name" : "holi", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000536", "name" : "Nucl_hrmn_rcpt_lig-bd", "description" : "Nuclear hormone receptor, ligand-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 213, "end" : 365, "hmmStart" : 1, "hmmEnd" : 158, "hmmLength" : 158, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-27, "score" : 106.5, "location-fragments" : [ { "start" : 213, "end" : 365, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-27, "score" : 106.5, "model-ac" : "SM00430" }, { "signature" : { "accession" : "PR00047", "name" : "STROIDFINGER", "description" : "C4-type steroid receptor zinc finger signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001628", "name" : "Znf_hrmn_rcpt", "description" : "Zinc finger, nuclear hormone receptor-type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "sequence-specific DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0043565" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" }, { "name" : "regulation of transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006355" }, { "name" : "DNA-binding transcription factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003700" } ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 25, "end" : 40, "pvalue" : 1.34E-8, "score" : 53.49, "motifNumber" : 2, "location-fragments" : [ { "start" : 25, "end" : 40, "dc-status" : "CONTINUOUS" } ] }, { "start" : 9, "end" : 25, "pvalue" : 1.23E-9, "score" : 61.37, "motifNumber" : 1, "location-fragments" : [ { "start" : 9, "end" : 25, "dc-status" : "CONTINUOUS" } ] }, { "start" : 58, "end" : 66, "pvalue" : 1.59E-4, "score" : 62.59, "motifNumber" : 3, "location-fragments" : [ { "start" : 58, "end" : 66, "dc-status" : "CONTINUOUS" } ] }, { "start" : 66, "end" : 74, "pvalue" : 0.00573, "score" : 48.0, "motifNumber" : 4, "location-fragments" : [ { "start" : 66, "end" : 74, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-17, "graphscan" : "IIII", "model-ac" : "PR00047" }, { "signature" : { "accession" : "PR01282", "name" : "COUPTNFACTOR", "description" : "COUP transcription factor (2F nuclear receptor) family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : null }, "locations" : [ { "start" : 359, "end" : 372, "pvalue" : 0.0264, "score" : 27.14, "motifNumber" : 7, "location-fragments" : [ { "start" : 359, "end" : 372, "dc-status" : "CONTINUOUS" } ] }, { "start" : 379, "end" : 390, "pvalue" : 0.00354, "score" : 42.22, "motifNumber" : 8, "location-fragments" : [ { "start" : 379, "end" : 390, "dc-status" : "CONTINUOUS" } ] }, { "start" : 315, "end" : 327, "pvalue" : 5.17E-4, "score" : 45.13, "motifNumber" : 6, "location-fragments" : [ { "start" : 315, "end" : 327, "dc-status" : "CONTINUOUS" } ] }, { "start" : 207, "end" : 223, "pvalue" : 3.23E-4, "score" : 52.55, "motifNumber" : 3, "location-fragments" : [ { "start" : 207, "end" : 223, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-5, "graphscan" : "..I..IiI.", "model-ac" : "PR01282" }, { "signature" : { "accession" : "PS51843", "name" : "NR_LBD", "description" : "Nuclear receptor (NR) ligand-binding (LBD) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000536", "name" : "Nucl_hrmn_rcpt_lig-bd", "description" : "Nuclear hormone receptor, ligand-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 177, "end" : 393, "score" : 38.355, "alignment" : "EVQHITPQDVTKSSPISpkkERQDDVSVDMPN-----------EGIYESAAKLLFLAVKWARSIPSFIQLPSHDQSLLLEDSWSELFALSAAQWSFALD-QGFLVINSA--APEYRHSAL---EETVRKLKGIVNRILTMRLDHTEFTCLKALVLFK-SDVAGLSEPSYIELLQDQTQVMLREYISVTS----KVRFGKLLLLLPVLASLEKRNLEELFFRKTIGNVSISSLLTDMLQQ-", "location-fragments" : [ { "start" : 177, "end" : 393, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51843" }, { "signature" : { "accession" : "PF00104", "name" : "Hormone_recep", "description" : "Ligand-binding domain of nuclear hormone receptor", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000536", "name" : "Nucl_hrmn_rcpt_lig-bd", "description" : "Nuclear hormone receptor, ligand-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 211, "end" : 377, "hmmStart" : 16, "hmmEnd" : 210, "hmmLength" : 211, "hmmBounds" : "INCOMPLETE", "evalue" : 3.2E-25, "score" : 89.0, "envelopeStart" : 205, "envelopeEnd" : 378, "postProcessed" : true, "location-fragments" : [ { "start" : 211, "end" : 377, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-25, "score" : 89.0, "model-ac" : "PF00104" }, { "signature" : { "accession" : "PTHR24083", "name" : "NUCLEAR HORMONE RECEPTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 378, "hmmStart" : 26, "hmmEnd" : 346, "hmmLength" : 346, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 378, "location-fragments" : [ { "start" : 5, "end" : 378, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-113, "familyName" : "NUCLEAR HORMONE RECEPTOR FAMILY", "score" : 382.0, "model-ac" : "PTHR24083" }, { "signature" : { "accession" : "PR00398", "name" : "STRDHORMONER", "description" : "Steroid hormone receptor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001723", "name" : "Nuclear_hrmn_rcpt", "description" : "Nuclear hormone receptor", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 70, "end" : 80, "pvalue" : 2.7E-4, "score" : 43.76, "motifNumber" : 1, "location-fragments" : [ { "start" : 70, "end" : 80, "dc-status" : "CONTINUOUS" } ] }, { "start" : 214, "end" : 235, "pvalue" : 4.68E-8, "score" : 34.55, "motifNumber" : 2, "location-fragments" : [ { "start" : 214, "end" : 235, "dc-status" : "CONTINUOUS" } ] }, { "start" : 235, "end" : 251, "pvalue" : 3.59E-6, "score" : 42.43, "motifNumber" : 3, "location-fragments" : [ { "start" : 235, "end" : 251, "dc-status" : "CONTINUOUS" } ] }, { "start" : 299, "end" : 314, "pvalue" : 1.47E-8, "score" : 41.22, "motifNumber" : 4, "location-fragments" : [ { "start" : 299, "end" : 314, "dc-status" : "CONTINUOUS" } ] }, { "start" : 353, "end" : 370, "pvalue" : 7.8E-6, "score" : 34.44, "motifNumber" : 5, "location-fragments" : [ { "start" : 353, "end" : 370, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.2E-24, "graphscan" : "IIIII", "model-ac" : "PR00398" }, { "signature" : { "accession" : "SSF48508", "name" : "Nuclear receptor ligand-binding domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035500", "name" : "NHR-like_dom_sf", "description" : "Nuclear hormone receptor-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 75, "end" : 391, "hmmLength" : 265, "location-fragments" : [ { "start" : 195, "end" : 391, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 75, "end" : 89, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.1E-50, "model-ac" : "0042042" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 174, "end" : 200, "location-fragments" : [ { "start" : 174, "end" : 200, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910426.1 PREDICTED: nuclear receptor subfamily 2 group E member 1-like [Bemisia tabaci]", "id" : "XP_018910426.1" }, { "name" : "XP_018910358.1 PREDICTED: nuclear receptor subfamily 2 group E member 1-like [Bemisia tabaci]", "id" : "XP_018910358.1" } ] },{ "sequence" : "MFSKFKGNPPNAPQTPLDNNPILQYFDVRKQTASAGPELIWKIHDGYRKSDGKEVSIFVFEKRLAEKLHKPKRKETVAEILRGGVRQLERFRHPRILQVVHAIEECSETIAFATEPVMASLANILAYHEHQGTGAGPPETGASAHAQPQHPIPRPPHACDYSFLGIELKYGFLQLTEALSFLHCIGHTLHHNVCPGSIFVNKKGIWKLGGLEFTER", "md5" : "41ef359a70abb83559251a59a9ff3762", "matches" : [ { "signature" : { "accession" : "PTHR12984:SF16", "name" : "BLACK MATCH, ISOFORM F", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 216, "hmmStart" : 4, "hmmEnd" : 176, "hmmLength" : 735, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 9, "envelopeEnd" : 216, "location-fragments" : [ { "start" : 14, "end" : 216, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-72, "familyName" : "BLACK MATCH, ISOFORM F", "score" : 248.0, "model-ac" : "PTHR12984:SF16" }, { "signature" : { "accession" : "PS50011", "name" : "PROTEIN_KINASE_DOM", "description" : "Protein kinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 26, "end" : 216, "score" : 10.309, "alignment" : "FDVRKQTASAGPELIWKIHDgyrKSDGKEVSIFVFEKRLAEKLhkpKRKETVAEILRGGvrQLerfRHPRILQVVHAIEECsETIAFATEPVM-ASLANILAYHEHQgtgagppetgasahaqpqhpiprpphacdysFLGIELKYGFLQLTEALSFLHCIgHTLHHNVCPGSIFVNKKGIWKLGGLEFTER---------------------------------------------------------------------------------------------------------------", "location-fragments" : [ { "start" : 26, "end" : 216, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50011" }, { "signature" : { "accession" : "G3DSA:3.30.200.20", "name" : "Phosphorylase Kinase; domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 115, "hmmStart" : 20, "hmmEnd" : 89, "hmmLength" : 90, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-15, "score" : 58.8, "envelopeStart" : 24, "envelopeEnd" : 115, "postProcessed" : true, "location-fragments" : [ { "start" : 24, "end" : 115, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.2E-16, "score" : 59.6, "model-ac" : "3vwaA01" }, { "signature" : { "accession" : "PTHR12984", "name" : "SCY1-RELATED S/T PROTEIN KINASE-LIKE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 216, "hmmStart" : 4, "hmmEnd" : 176, "hmmLength" : 735, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 9, "envelopeEnd" : 216, "location-fragments" : [ { "start" : 14, "end" : 216, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-72, "familyName" : "BLACK MATCH, ISOFORM F", "score" : 248.0, "model-ac" : "PTHR12984" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 211, "hmmLength" : 346, "location-fragments" : [ { "start" : 46, "end" : 131, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 163, "end" : 211, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.63E-9, "model-ac" : "0046180" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 130, "end" : 151, "location-fragments" : [ { "start" : 130, "end" : 151, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.10.510.10", "name" : "Transferase(Phosphotransferase) domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 157, "end" : 215, "hmmStart" : 17, "hmmEnd" : 61, "hmmLength" : 143, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-16, "score" : 61.8, "envelopeStart" : 157, "envelopeEnd" : 215, "postProcessed" : true, "location-fragments" : [ { "start" : 157, "end" : 215, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-16, "score" : 62.8, "model-ac" : "3vwaA02" } ], "xref" : [ { "name" : "XP_018910233.1 PREDICTED: SCY1-like protein 2 [Bemisia tabaci]", "id" : "XP_018910233.1" } ] },{ "sequence" : "MFPHHPDFHPRYRKMESSSPSSCMDQFASSPDTSTMTSRLAESEIPLDCLRNRRRKPDFNFNNVPYLVKHEEYNTTTYNKTPSYSKPPPLSRVTFSPEQISCMCEALQQANDMDRLAEFVWSLPESEQLKGQEAVLRARALIAFKKGQFKELFEILEKHEFSPKHHKKLQFLWYEGHYKEAENTRGRALCAVDKYRLRKKFPLPITIWDGEDTVYCFKESARKVLKKSYMTSRYPTQDEKRLLSNETGLTMVQVSNWFKNRRQRDRPPAKSSSGSSEDLLPTSSLMGSSPSTASMKSTFSYGGVAGVGGTETLRAGSNDQNQVLYSAANYHFSGCHGYETSLLPLAAVSHA", "md5" : "4da21f5e32ef466d58adcaa37f34ebd9", "matches" : [ { "signature" : { "accession" : "PS50071", "name" : "HOMEOBOX_2", "description" : "'Homeobox' domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001356", "name" : "Homeobox_dom", "description" : "Homeobox domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 217, "end" : 268, "score" : 13.88, "alignment" : "---------FKESARKVLKKSYMTSRYPTQDEKRLLSNETGLTMVQVSNWFKNRRQRDRPP", "location-fragments" : [ { "start" : 217, "end" : 268, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50071" }, { "signature" : { "accession" : "SSF46689", "name" : "Homeodomain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009057", "name" : "Homeobox-like_sf", "description" : "Homeobox-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 208, "end" : 271, "hmmLength" : 76, "location-fragments" : [ { "start" : 208, "end" : 271, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.84E-16, "model-ac" : "0052496" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 260, "end" : 287, "location-fragments" : [ { "start" : 260, "end" : 287, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 40, "location-fragments" : [ { "start" : 15, "end" : 40, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR10390:SF64", "name" : "SIX HOMEOBOX 4A-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 91, "end" : 275, "hmmStart" : 69, "hmmEnd" : 254, "hmmLength" : 645, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 68, "envelopeEnd" : 330, "location-fragments" : [ { "start" : 91, "end" : 275, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.5E-93, "familyName" : "SIX HOMEOBOX 4A-RELATED", "score" : 315.2, "model-ac" : "PTHR10390:SF64" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 40, "location-fragments" : [ { "start" : 7, "end" : 40, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00086", "name" : "homeodomain", "description" : "homeodomain", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR001356", "name" : "Homeobox_dom", "description" : "Homeobox domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 215, "end" : 268, "sites" : [ { "description" : "specific DNA base contacts", "numLocations" : 5, "siteLocations" : [ { "start" : 256, "end" : 256, "residue" : "N" }, { "start" : 263, "end" : 263, "residue" : "Q" }, { "start" : 259, "end" : 259, "residue" : "K" }, { "start" : 216, "end" : 216, "residue" : "C" }, { "start" : 260, "end" : 260, "residue" : "N" } ] } ], "evalue" : 2.80468E-14, "score" : 64.572, "location-fragments" : [ { "start" : 215, "end" : 268, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00086" }, { "signature" : { "accession" : "SM00389", "name" : "HOX_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001356", "name" : "Homeobox_dom", "description" : "Homeobox domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 210, "end" : 272, "hmmStart" : 1, "hmmEnd" : 63, "hmmLength" : 63, "hmmBounds" : "COMPLETE", "evalue" : 8.2E-14, "score" : 61.9, "location-fragments" : [ { "start" : 210, "end" : 272, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.2E-14, "score" : 61.9, "model-ac" : "SM00389" }, { "signature" : { "accession" : "PTHR10390", "name" : "HOMEOBOX PROTEIN SIX", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 91, "end" : 275, "hmmStart" : 69, "hmmEnd" : 254, "hmmLength" : 645, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 68, "envelopeEnd" : 330, "location-fragments" : [ { "start" : 91, "end" : 275, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.5E-93, "familyName" : "SIX HOMEOBOX 4A-RELATED", "score" : 315.2, "model-ac" : "PTHR10390" }, { "signature" : { "accession" : "G3DSA:1.10.10.60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 213, "end" : 278, "hmmStart" : 14, "hmmEnd" : 73, "hmmLength" : 83, "hmmBounds" : "COMPLETE", "evalue" : 3.8E-16, "score" : 60.3, "envelopeStart" : 213, "envelopeEnd" : 278, "postProcessed" : true, "location-fragments" : [ { "start" : 213, "end" : 278, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-16, "score" : 62.2, "model-ac" : "2dmnA00" }, { "signature" : { "accession" : "PF00046", "name" : "Homeodomain", "description" : "Homeodomain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001356", "name" : "Homeobox_dom", "description" : "Homeobox domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 216, "end" : 266, "hmmStart" : 6, "hmmEnd" : 56, "hmmLength" : 57, "hmmBounds" : "INCOMPLETE", "evalue" : 5.7E-13, "score" : 48.5, "envelopeStart" : 215, "envelopeEnd" : 267, "postProcessed" : true, "location-fragments" : [ { "start" : 216, "end" : 266, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-14, "score" : 52.7, "model-ac" : "PF00046" }, { "signature" : { "accession" : "PS00027", "name" : "HOMEOBOX_1", "description" : "'Homeobox' domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017970", "name" : "Homeobox_CS", "description" : "Homeobox, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "DNA-binding transcription factor activity, RNA polymerase II-specific", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0000981" }, { "name" : "regulation of transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006355" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 243, "end" : 266, "level" : "STRONG", "cigarAlignment" : "2M2I1M1I2M2I6M1I1M5I1M", "alignment" : "LSneTgLTmvQVSNWFkNrrqrdR", "location-fragments" : [ { "start" : 243, "end" : 266, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00027" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 269, "end" : 287, "location-fragments" : [ { "start" : 269, "end" : 287, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF16878", "name" : "SIX1_SD", "description" : "Transcriptional regulator, SIX1, N-terminal SD domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR031701", "name" : "SIX1_SD", "description" : "Homeobox protein SIX1, N-terminal SD domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 95, "end" : 204, "hmmStart" : 1, "hmmEnd" : 114, "hmmLength" : 115, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.2E-44, "score" : 150.6, "envelopeStart" : 95, "envelopeEnd" : 205, "postProcessed" : true, "location-fragments" : [ { "start" : 95, "end" : 204, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-45, "score" : 152.8, "model-ac" : "PF16878" } ], "xref" : [ { "name" : "XP_018909740.1 PREDICTED: homeobox protein SIX6-like [Bemisia tabaci]", "id" : "XP_018909740.1" } ] },{ "sequence" : "MREYKMVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKTGQGFILVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEDERVVGKDQGVNLARQFNCAFMETSAKAKINVYDIFFDLVRQVNKKSPEKKQKQKKKSLCKLL", "md5" : "6e9314644bc4ba7b9eed9072e64ffe56", "matches" : [ { "signature" : { "accession" : "cd04175", "name" : "Rap1", "description" : "Rap1", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR038851", "name" : "Rap1", "description" : "Ras-related protein Rap1", "type" : "FAMILY", "goXRefs" : [ { "name" : "GTPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003924" }, { "name" : "Rap protein signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0032486" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3, "end" : 165, "sites" : [ { "description" : "G1 box", "numLocations" : 8, "siteLocations" : [ { "start" : 11, "end" : 11, "residue" : "S" }, { "start" : 12, "end" : 12, "residue" : "G" }, { "start" : 14, "end" : 14, "residue" : "V" }, { "start" : 17, "end" : 17, "residue" : "S" }, { "start" : 10, "end" : 10, "residue" : "G" }, { "start" : 16, "end" : 16, "residue" : "K" }, { "start" : 15, "end" : 15, "residue" : "G" }, { "start" : 13, "end" : 13, "residue" : "G" } ] }, { "description" : "effector interaction site", "numLocations" : 9, "siteLocations" : [ { "start" : 38, "end" : 38, "residue" : "D" }, { "start" : 31, "end" : 31, "residue" : "K" }, { "start" : 36, "end" : 36, "residue" : "I" }, { "start" : 25, "end" : 25, "residue" : "Q" }, { "start" : 33, "end" : 33, "residue" : "D" }, { "start" : 41, "end" : 41, "residue" : "R" }, { "start" : 39, "end" : 39, "residue" : "S" }, { "start" : 40, "end" : 40, "residue" : "Y" }, { "start" : 37, "end" : 37, "residue" : "E" } ] }, { "description" : "G3 box", "numLocations" : 4, "siteLocations" : [ { "start" : 59, "end" : 59, "residue" : "A" }, { "start" : 60, "end" : 60, "residue" : "G" }, { "start" : 57, "end" : 57, "residue" : "D" }, { "start" : 58, "end" : 58, "residue" : "T" } ] }, { "description" : "G4 box", "numLocations" : 4, "siteLocations" : [ { "start" : 118, "end" : 118, "residue" : "C" }, { "start" : 117, "end" : 117, "residue" : "K" }, { "start" : 119, "end" : 119, "residue" : "D" }, { "start" : 116, "end" : 116, "residue" : "N" } ] }, { "description" : "Switch II region", "numLocations" : 19, "siteLocations" : [ { "start" : 59, "end" : 59, "residue" : "A" }, { "start" : 60, "end" : 60, "residue" : "G" }, { "start" : 65, "end" : 65, "residue" : "T" }, { "start" : 67, "end" : 67, "residue" : "M" }, { "start" : 72, "end" : 72, "residue" : "M" }, { "start" : 76, "end" : 76, "residue" : "Q" }, { "start" : 68, "end" : 68, "residue" : "R" }, { "start" : 74, "end" : 74, "residue" : "T" }, { "start" : 75, "end" : 75, "residue" : "G" }, { "start" : 71, "end" : 71, "residue" : "Y" }, { "start" : 62, "end" : 62, "residue" : "E" }, { "start" : 70, "end" : 70, "residue" : "L" }, { "start" : 63, "end" : 63, "residue" : "Q" }, { "start" : 77, "end" : 77, "residue" : "G" }, { "start" : 61, "end" : 61, "residue" : "T" }, { "start" : 64, "end" : 64, "residue" : "F" }, { "start" : 69, "end" : 69, "residue" : "D" }, { "start" : 66, "end" : 66, "residue" : "A" }, { "start" : 73, "end" : 73, "residue" : "K" } ] }, { "description" : "G2 box", "numLocations" : 1, "siteLocations" : [ { "start" : 35, "end" : 35, "residue" : "T" } ] }, { "description" : "G5 box", "numLocations" : 3, "siteLocations" : [ { "start" : 147, "end" : 147, "residue" : "A" }, { "start" : 146, "end" : 146, "residue" : "S" }, { "start" : 148, "end" : 148, "residue" : "K" } ] }, { "description" : "putative GEF interaction site", "numLocations" : 12, "siteLocations" : [ { "start" : 55, "end" : 55, "residue" : "I" }, { "start" : 59, "end" : 59, "residue" : "A" }, { "start" : 60, "end" : 60, "residue" : "G" }, { "start" : 54, "end" : 54, "residue" : "E" }, { "start" : 17, "end" : 17, "residue" : "S" }, { "start" : 57, "end" : 57, "residue" : "D" }, { "start" : 41, "end" : 41, "residue" : "R" }, { "start" : 32, "end" : 32, "residue" : "Y" }, { "start" : 40, "end" : 40, "residue" : "Y" }, { "start" : 34, "end" : 34, "residue" : "P" }, { "start" : 148, "end" : 148, "residue" : "K" }, { "start" : 18, "end" : 18, "residue" : "A" } ] }, { "description" : "putative GDI interaction site", "numLocations" : 4, "siteLocations" : [ { "start" : 11, "end" : 11, "residue" : "S" }, { "start" : 12, "end" : 12, "residue" : "G" }, { "start" : 59, "end" : 59, "residue" : "A" }, { "start" : 60, "end" : 60, "residue" : "G" } ] }, { "description" : "Switch I region", "numLocations" : 8, "siteLocations" : [ { "start" : 38, "end" : 38, "residue" : "D" }, { "start" : 35, "end" : 35, "residue" : "T" }, { "start" : 36, "end" : 36, "residue" : "I" }, { "start" : 33, "end" : 33, "residue" : "D" }, { "start" : 39, "end" : 39, "residue" : "S" }, { "start" : 40, "end" : 40, "residue" : "Y" }, { "start" : 37, "end" : 37, "residue" : "E" }, { "start" : 34, "end" : 34, "residue" : "P" } ] }, { "description" : "GTP/Mg2+ binding site", "numLocations" : 20, "siteLocations" : [ { "start" : 12, "end" : 12, "residue" : "G" }, { "start" : 60, "end" : 60, "residue" : "G" }, { "start" : 119, "end" : 119, "residue" : "D" }, { "start" : 146, "end" : 146, "residue" : "S" }, { "start" : 116, "end" : 116, "residue" : "N" }, { "start" : 14, "end" : 14, "residue" : "V" }, { "start" : 35, "end" : 35, "residue" : "T" }, { "start" : 147, "end" : 147, "residue" : "A" }, { "start" : 30, "end" : 30, "residue" : "E" }, { "start" : 17, "end" : 17, "residue" : "S" }, { "start" : 16, "end" : 16, "residue" : "K" }, { "start" : 28, "end" : 28, "residue" : "F" }, { "start" : 15, "end" : 15, "residue" : "G" }, { "start" : 117, "end" : 117, "residue" : "K" }, { "start" : 32, "end" : 32, "residue" : "Y" }, { "start" : 13, "end" : 13, "residue" : "G" }, { "start" : 29, "end" : 29, "residue" : "V" }, { "start" : 34, "end" : 34, "residue" : "P" }, { "start" : 148, "end" : 148, "residue" : "K" }, { "start" : 18, "end" : 18, "residue" : "A" } ] } ], "evalue" : 1.05972E-118, "score" : 331.019, "location-fragments" : [ { "start" : 3, "end" : 165, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd04175" }, { "signature" : { "accession" : "PTHR24070", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR020849", "name" : "Small_GTPase_Ras-type", "description" : "Small GTPase superfamily, Ras-type", "type" : "FAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "GTP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005525" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 183, "hmmStart" : 1, "hmmEnd" : 184, "hmmLength" : 185, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 184, "location-fragments" : [ { "start" : 1, "end" : 183, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-111, "familyName" : "RAS-RELATED PROTEIN RAP-1A", "score" : 370.4, "model-ac" : "PTHR24070" }, { "signature" : { "accession" : "PR00449", "name" : "RASTRNSFRMNG", "description" : "Transforming protein P21 ras signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : null }, "locations" : [ { "start" : 4, "end" : 25, "pvalue" : 3.94E-13, "score" : 47.23, "motifNumber" : 1, "location-fragments" : [ { "start" : 4, "end" : 25, "dc-status" : "CONTINUOUS" } ] }, { "start" : 27, "end" : 43, "pvalue" : 2.4E-6, "score" : 35.81, "motifNumber" : 2, "location-fragments" : [ { "start" : 27, "end" : 43, "dc-status" : "CONTINUOUS" } ] }, { "start" : 107, "end" : 120, "pvalue" : 2.99E-9, "score" : 58.45, "motifNumber" : 4, "location-fragments" : [ { "start" : 107, "end" : 120, "dc-status" : "CONTINUOUS" } ] }, { "start" : 142, "end" : 164, "pvalue" : 1.04E-10, "score" : 40.59, "motifNumber" : 5, "location-fragments" : [ { "start" : 142, "end" : 164, "dc-status" : "CONTINUOUS" } ] }, { "start" : 44, "end" : 66, "pvalue" : 2.72E-9, "score" : 43.23, "motifNumber" : 3, "location-fragments" : [ { "start" : 44, "end" : 66, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-40, "graphscan" : "IIIII", "model-ac" : "PR00449" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 164, "hmmLength" : 177, "location-fragments" : [ { "start" : 2, "end" : 164, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.05E-52, "model-ac" : "0053591" }, { "signature" : { "accession" : "PTHR24070:SF395", "name" : "RAS-RELATED PROTEIN RAP-1A", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 183, "hmmStart" : 1, "hmmEnd" : 184, "hmmLength" : 185, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 184, "location-fragments" : [ { "start" : 1, "end" : 183, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-111, "familyName" : "RAS-RELATED PROTEIN RAP-1A", "score" : 370.4, "model-ac" : "PTHR24070:SF395" }, { "signature" : { "accession" : "TIGR00231", "name" : "TIGR00231", "description" : "small_GTP: small GTP-binding protein domain", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR005225", "name" : "Small_GTP-bd_dom", "description" : "Small GTP-binding protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "GTP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005525" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 157, "hmmStart" : 1, "hmmEnd" : 159, "hmmLength" : 164, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.3E-33, "score" : 114.0, "envelopeStart" : 1, "envelopeEnd" : 163, "postProcessed" : false, "location-fragments" : [ { "start" : 1, "end" : 157, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-33, "score" : 114.3, "model-ac" : "TIGR00231" }, { "signature" : { "accession" : "PS51421", "name" : "RAS", "description" : "small GTPase Ras family profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR020849", "name" : "Small_GTPase_Ras-type", "description" : "Small GTPase superfamily, Ras-type", "type" : "FAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "GTP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005525" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 184, "score" : 45.657, "alignment" : "--MREYKMVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKTGQGFILVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEDERVVGKDQGVNLARQFNCAFMETSAKAKINVYDIFFDLVRQVNKKSPEKKQK----QKKKS----LCKLL", "location-fragments" : [ { "start" : 1, "end" : 184, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51421" }, { "signature" : { "accession" : "SM00173", "name" : "ras_sub_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 167, "hmmStart" : 1, "hmmEnd" : 167, "hmmLength" : 167, "hmmBounds" : "COMPLETE", "evalue" : 6.1E-123, "score" : 424.4, "location-fragments" : [ { "start" : 1, "end" : 167, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.1E-123, "score" : 424.4, "model-ac" : "SM00173" }, { "signature" : { "accession" : "PF00071", "name" : "Ras", "description" : "Ras family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001806", "name" : "Small_GTPase", "description" : "Small GTPase", "type" : "FAMILY", "goXRefs" : [ { "name" : "GTPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003924" }, { "name" : "GTP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005525" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5, "end" : 165, "hmmStart" : 1, "hmmEnd" : 161, "hmmLength" : 162, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.7E-57, "score" : 192.9, "envelopeStart" : 5, "envelopeEnd" : 166, "postProcessed" : true, "location-fragments" : [ { "start" : 5, "end" : 165, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-57, "score" : 193.1, "model-ac" : "PF00071" }, { "signature" : { "accession" : "SM00176", "name" : "ran_sub_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 183, "hmmStart" : 1, "hmmEnd" : 202, "hmmLength" : 202, "hmmBounds" : "COMPLETE", "evalue" : 4.0E-4, "score" : 10.1, "location-fragments" : [ { "start" : 9, "end" : 183, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-4, "score" : 10.1, "model-ac" : "SM00176" }, { "signature" : { "accession" : "SM00174", "name" : "rho_sub_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 6, "end" : 167, "hmmStart" : 1, "hmmEnd" : 180, "hmmLength" : 180, "hmmBounds" : "COMPLETE", "evalue" : 9.9E-12, "score" : 30.6, "location-fragments" : [ { "start" : 6, "end" : 167, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-12, "score" : 30.6, "model-ac" : "SM00174" }, { "signature" : { "accession" : "SM00175", "name" : "rab_sub_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 4, "end" : 167, "hmmStart" : 1, "hmmEnd" : 172, "hmmLength" : 172, "hmmBounds" : "COMPLETE", "evalue" : 3.2E-35, "score" : 133.0, "location-fragments" : [ { "start" : 4, "end" : 167, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-35, "score" : 133.0, "model-ac" : "SM00175" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 170, "hmmStart" : 3, "hmmEnd" : 168, "hmmLength" : 172, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-65, "score" : 222.1, "envelopeStart" : 1, "envelopeEnd" : 170, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 170, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-65, "score" : 222.4, "model-ac" : "2erxA00" } ], "xref" : [ { "name" : "XP_018909626.1 PREDICTED: ras-like protein 3 [Bemisia tabaci]", "id" : "XP_018909626.1" } ] },{ "sequence" : "MEVAQRSWRLVEFTAHTAPVNCLALGHKSGRVLVTGGDDKKVNLWAVGKENCIMSLSGHGTPIETVRFSSSEDMVCAGSRDGVLKVWDLEAAKIVRTLIGHQDCMKSVDFHPYAEFLASGSVDSTIKLWDIRKKGCIFTYRGHIGSVNSVKFSPDGQWIASGGEDSTVKIWDLRTGSVLHDFIKHDGPVLSVEYHPHEFLLASSSTDKTVHFWDLDKFTSISATEKQAHASRCIRFSEGGECLFAGACDTLNVFGWEPLRSLDTVFTQWSKIRDISTVGSQLIGAGYQAEGVMIYVVDLAKVCPIGKPLPPASPFAHGMSIRKSFNKQKPAPKSTAVKHQKPIEENETEPEDENLADIPDVNNYEAVFCPNRTLNRSPPPNEELFTPPGNITELNAPAQTSLHSGSQLAAETEEEYYEETEPSPKDHAPKSIYVSKNKQSSSSEVMSPVSSSICHTVSTLTSGMTHTAPGQNHSSMPASLNSLSPTSSSDHSFSRLGSANHADSSKEARSQSYDDPSKVCNFESSPSEPAISNSARKVGNGIGVKVSNNHKPELPPKPKYQLSVKQHQNNAKNIMMKPGKRPGAGEDDNIEYIPMTGDTPVGLEPNEFLPKRGSGGQLSEAEVISSVMRGHEDMMRVLISRQRNLQIIFSVWHTKDLKSAVEMATDMNDLSVVVDLLSALTRKPNLWSLDLCNLLLPSIRELLQSKYETYVTVGCDALRLILRNFSSVIRNNVQWSCPTIGVDITKEERYNKCKGCHNQLVSIRAFLLKRQTVQGKLGQMFRELVILLEAIDAT", "md5" : "087ceae6b288ba77157a2f6ce3eaee74", "matches" : [ { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 140, "end" : 181, "score" : 19.264, "alignment" : "YRGHIGSVNSVKFSPDGQWIASGGEDSTVKIWDLRTGSVLHD", "location-fragments" : [ { "start" : 140, "end" : 181, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "MF_03022", "name" : "Katanin_p80_B1", "description" : "Katanin p80 WD40 repeat-containing subunit B1 [KATNB1].", "signatureLibraryRelease" : { "library" : "HAMAP", "version" : "2020_01" }, "entry" : { "accession" : "IPR026962", "name" : "Katanin_bsu1", "description" : "Katanin p80 subunit B1", "type" : "FAMILY", "goXRefs" : [ { "name" : "microtubule severing", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0051013" }, { "name" : "katanin complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0008352" }, { "name" : "microtubule binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008017" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 791, "score" : 19.619, "alignment" : "EVAQRSWRLVEFTAHTAPVNCLALGHKSGRVLVTGGDDKKVNLWAVGKENCIMSLSGHGTPIETVRFSSSEDMVCAGSRDGVLKVWDLEAAKIVRTLIGHQDCMKSVDFHPYAEFLASGSVDSTIKLWDIRKKGCIFTYRGHIGSVNSVKFSPDGQWIASGGEDSTVKIWDLRTGSVLHDFIKHDGPVLSVEYHPHEFLLASSSTDKTVHFWDLDKFTSISAT--EkqahAS--RCIRFSEGGECLFAGACDTLNVFGWEPLRSLDTVFTQWSKIRDISTVGSQLIGAGYQAEGVMIYVVDLAKVcpigKPL-----PPA-------S---P--FAHGMSIRKSFNKQKPAPKSTAVKHQK------------------PIEENE-TEPEDENLADIPD---VNnYEAVFCPNRTLNRSPPPNEelfTPpgNiTElnaP-----AQ----TSlhSgSQlaaET-EeeyyeetepspkdhApksiyvskNKQSsssevmsPvSSsichTVS----TlTSgmthtapgqN-HssmpaslNslsPtssSD-----H-----SfSRlgsanhadSSkEarsqSYDdpSKVcnfES-S-P---SE-PaIS--N-S-ArkvgngIgVkvsnnhkPElppKpkyqlsvkqhqnnaKNimmkpgkRPgAgeddnieyiPMtgDtpvglEPnEFLP-----KRG----SGgQ----LSEAEVISSVMRGHEDMMRVLISRQRNLQIIFSVWHTKDLKSAVEMATDMNDLSVVVDLLSALTRKPNLWSLDLCNLLLPSIRELLQSKYETYVTVGCDALRLILRNFSSVIRNNVQWSCPTIGVDITKEERYNKCKGCHNQLVSIRAFLLKRQTVQGKLGQMFRELVILLEAI", "location-fragments" : [ { "start" : 2, "end" : 791, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "MF_03022" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 392, "end" : 408, "location-fragments" : [ { "start" : 392, "end" : 408, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS00678", "name" : "WD_REPEATS_1", "description" : "Trp-Asp (WD) repeats signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019775", "name" : "WD40_repeat_CS", "description" : "WD40 repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 201, "end" : 215, "level" : "STRONG", "cigarAlignment" : "4M2I1M1I7M", "alignment" : "LASSstDkTVHFWDL", "location-fragments" : [ { "start" : 201, "end" : 215, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00678" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 182, "end" : 223, "score" : 13.583, "alignment" : "FIKHDGPVLSVEYHPHEFLLASSSTDKTVHFWDLDKFTSISA", "location-fragments" : [ { "start" : 182, "end" : 223, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "PTHR19845:SF0", "name" : "KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 788, "hmmStart" : 1, "hmmEnd" : 753, "hmmLength" : 756, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 791, "location-fragments" : [ { "start" : 1, "end" : 788, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-198, "familyName" : "KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1", "score" : 663.6, "model-ac" : "PTHR19845:SF0" }, { "signature" : { "accession" : "SM00320", "name" : "WD40_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 219, "end" : 257, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 180.0, "score" : 2.7, "location-fragments" : [ { "start" : 219, "end" : 257, "dc-status" : "CONTINUOUS" } ] }, { "start" : 175, "end" : 214, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 3.2E-8, "score" : 43.3, "location-fragments" : [ { "start" : 175, "end" : 214, "dc-status" : "CONTINUOUS" } ] }, { "start" : 6, "end" : 46, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 7.1E-5, "score" : 32.2, "location-fragments" : [ { "start" : 6, "end" : 46, "dc-status" : "CONTINUOUS" } ] }, { "start" : 133, "end" : 172, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-13, "score" : 60.9, "location-fragments" : [ { "start" : 133, "end" : 172, "dc-status" : "CONTINUOUS" } ] }, { "start" : 49, "end" : 88, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-7, "score" : 41.6, "location-fragments" : [ { "start" : 49, "end" : 88, "dc-status" : "CONTINUOUS" } ] }, { "start" : 91, "end" : 130, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 5.9E-9, "score" : 45.8, "location-fragments" : [ { "start" : 91, "end" : 130, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-63, "score" : 226.5, "model-ac" : "SM00320" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 135, "end" : 281, "hmmStart" : 103, "hmmEnd" : 221, "hmmLength" : 451, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.1E-32, "score" : 115.3, "envelopeStart" : 132, "envelopeEnd" : 281, "postProcessed" : true, "location-fragments" : [ { "start" : 135, "end" : 281, "dc-status" : "CONTINUOUS" } ] }, { "start" : 4, "end" : 134, "hmmStart" : 109, "hmmEnd" : 234, "hmmLength" : 451, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.5E-37, "score" : 130.0, "envelopeStart" : 4, "envelopeEnd" : 137, "postProcessed" : true, "location-fragments" : [ { "start" : 4, "end" : 134, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-70, "score" : 239.1, "model-ac" : "4j0xA00" }, { "signature" : { "accession" : "PR00320", "name" : "GPROTEINBRPT", "description" : "G protein beta WD-40 repeat signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR020472", "name" : "G-protein_beta_WD-40_rep", "description" : "G-protein beta WD-40 repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 159, "end" : 173, "pvalue" : 9.41E-6, "score" : 41.23, "motifNumber" : 3, "location-fragments" : [ { "start" : 159, "end" : 173, "dc-status" : "CONTINUOUS" } ] }, { "start" : 75, "end" : 89, "pvalue" : 1.44E-4, "score" : 35.08, "motifNumber" : 1, "location-fragments" : [ { "start" : 75, "end" : 89, "dc-status" : "CONTINUOUS" } ] }, { "start" : 117, "end" : 131, "pvalue" : 2.84E-6, "score" : 46.62, "motifNumber" : 2, "location-fragments" : [ { "start" : 117, "end" : 131, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.2E-9, "graphscan" : "III", "model-ac" : "PR00320" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 55, "score" : 11.712, "alignment" : "FTAHTAPVNCLALGHKsGRVLVTGGDDKKVNLWAVGKENCIMS", "location-fragments" : [ { "start" : 13, "end" : 55, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "PS50294", "name" : "WD_REPEATS_REGION", "description" : "Trp-Asp (WD) repeats circular profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR017986", "name" : "WD40_repeat_dom", "description" : "WD40-repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 223, "score" : 58.108, "alignment" : "FTAHTAPVNCLALGHKsGRVLVTGGDDKKVNLWAVGKENCIMSLSGHGTPIETVRFSSSEDMVCAGSRDGVLKVWDLEAAKIVRTLIGHQDCMKSVDFHPYAEFLASGSVDSTIKLWDIRKKGCIFTYRGHIGSVNSVKFSPDGQWIASGGEDSTVKIWDLRTGSVLHDFIKHDGPVLSVEYHPHEFLLASSSTDKTVHFWDLDKFTSISA", "location-fragments" : [ { "start" : 13, "end" : 223, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50294" }, { "signature" : { "accession" : "PTHR19845", "name" : "KATANIN P80 SUBUNIT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 788, "hmmStart" : 1, "hmmEnd" : 753, "hmmLength" : 756, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 791, "location-fragments" : [ { "start" : 1, "end" : 788, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-198, "familyName" : "KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1", "score" : 663.6, "model-ac" : "PTHR19845" }, { "signature" : { "accession" : "PS00678", "name" : "WD_REPEATS_1", "description" : "Trp-Asp (WD) repeats signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019775", "name" : "WD40_repeat_CS", "description" : "WD40 repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 75, "end" : 89, "level" : "STRONG", "cigarAlignment" : "4M2I1M1I7M", "alignment" : "VCAGsrDgVLKVWDL", "location-fragments" : [ { "start" : 75, "end" : 89, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00678" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 322, "end" : 555, "location-fragments" : [ { "start" : 322, "end" : 555, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF50978", "name" : "WD40 repeat-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036322", "name" : "WD40_repeat_dom_sf", "description" : "WD40-repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 265, "hmmLength" : 317, "location-fragments" : [ { "start" : 8, "end" : 265, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.97E-71, "model-ac" : "0053623" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 98, "end" : 139, "score" : 15.454, "alignment" : "LIGHQDCMKSVDFHPYAEFLASGSVDSTIKLWDIRKKGCIFT", "location-fragments" : [ { "start" : 98, "end" : 139, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "PS00678", "name" : "WD_REPEATS_1", "description" : "Trp-Asp (WD) repeats signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019775", "name" : "WD40_repeat_CS", "description" : "WD40 repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 117, "end" : 131, "level" : "STRONG", "cigarAlignment" : "4M2I1M1I7M", "alignment" : "LASGsvDsTIKLWDI", "location-fragments" : [ { "start" : 117, "end" : 131, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00678" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 514, "end" : 534, "location-fragments" : [ { "start" : 514, "end" : 534, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00400", "name" : "WD40", "description" : "WD domain, G-beta repeat", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 136, "end" : 172, "hmmStart" : 3, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.0E-13, "score" : 49.6, "envelopeStart" : 134, "envelopeEnd" : 172, "postProcessed" : true, "location-fragments" : [ { "start" : 136, "end" : 172, "dc-status" : "CONTINUOUS" } ] }, { "start" : 11, "end" : 45, "hmmStart" : 5, "hmmEnd" : 37, "hmmLength" : 38, "hmmBounds" : "INCOMPLETE", "evalue" : 1.7E-4, "score" : 22.3, "envelopeStart" : 7, "envelopeEnd" : 45, "postProcessed" : true, "location-fragments" : [ { "start" : 11, "end" : 45, "dc-status" : "CONTINUOUS" } ] }, { "start" : 51, "end" : 88, "hmmStart" : 2, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.9E-7, "score" : 31.6, "envelopeStart" : 50, "envelopeEnd" : 88, "postProcessed" : true, "location-fragments" : [ { "start" : 51, "end" : 88, "dc-status" : "CONTINUOUS" } ] }, { "start" : 177, "end" : 214, "hmmStart" : 2, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 0.0011, "score" : 19.7, "envelopeStart" : 176, "envelopeEnd" : 214, "postProcessed" : true, "location-fragments" : [ { "start" : 177, "end" : 214, "dc-status" : "CONTINUOUS" } ] }, { "start" : 94, "end" : 130, "hmmStart" : 3, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 9.9E-8, "score" : 32.5, "envelopeStart" : 92, "envelopeEnd" : 130, "postProcessed" : true, "location-fragments" : [ { "start" : 94, "end" : 130, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-44, "score" : 148.7, "model-ac" : "PF00400" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 433, "end" : 506, "location-fragments" : [ { "start" : 433, "end" : 506, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF13925", "name" : "Katanin_con80", "description" : "con80 domain of Katanin", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR028021", "name" : "Katanin_C-terminal", "description" : "Katanin p80 subunit, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 630, "end" : 786, "hmmStart" : 2, "hmmEnd" : 158, "hmmLength" : 160, "hmmBounds" : "INCOMPLETE", "evalue" : 9.6E-54, "score" : 181.8, "envelopeStart" : 629, "envelopeEnd" : 788, "postProcessed" : true, "location-fragments" : [ { "start" : 630, "end" : 786, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-54, "score" : 182.3, "model-ac" : "PF13925" }, { "signature" : { "accession" : "cd00200", "name" : "WD40", "description" : "WD40", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 214, "sites" : [ ], "evalue" : 1.35571E-65, "score" : 218.358, "location-fragments" : [ { "start" : 10, "end" : 214, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00200" }, { "signature" : { "accession" : "PS00678", "name" : "WD_REPEATS_1", "description" : "Trp-Asp (WD) repeats signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019775", "name" : "WD40_repeat_CS", "description" : "WD40 repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 159, "end" : 173, "level" : "STRONG", "cigarAlignment" : "4M2I1M1I7M", "alignment" : "IASGgeDsTVKIWDL", "location-fragments" : [ { "start" : 159, "end" : 173, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00678" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 56, "end" : 97, "score" : 15.488, "alignment" : "LSGHGTPIETVRFSSSEDMVCAGSRDGVLKVWDLEAAKIVRT", "location-fragments" : [ { "start" : 56, "end" : 97, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" } ], "xref" : [ { "name" : "XP_018910098.1 PREDICTED: katanin p80 WD40 repeat-containing subunit B1-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910098.1" } ] },{ "sequence" : "MPKGRLDYLKRILPHLQNQSEDCLYLNIYAPAQGSGDPTSKYPVLVFIHGESYSWNSGNPYDGTVLSSYGKLVVVTVNYRLGVLGFLNANPDPGLRAPANYGLMDQLAALHWIQENIAVFGGDPTNVTLLGHGTGAACVNFLLTSNAVPDGVLFHRAILMSGSSLSPWALVRDPSRWSREIAEQAGCNPQLPHTLLLKCLRDKPLANLTAAHLKDVPPFTATFGPSVDGVIIDTGLNQISKQDSSHQQLEYNLGSGPGRPEEVRQEKEDALIAGGYAHVVLNDPIMRKNMISKLSRYDLLIGVTRAEAFFTFNADDIQYGIEADRRSKILTSFVKNTYRYHLSEILATIVNEYTDWERPVQHPVNIRDETLEALSDAQVVAPVVNTADLHSIARRNSYLYVFDYQTKYGDYQQRQGCIFGEDLPYVFGAPLVSGGAGLIHFPRNFTKAEVALAETTMNYWSNFIRTGNPNEMQETDTSRAERNRFKNIEWTAYEAVHKKYLSLDTKPKLKNHFRAHRLSFWLNLIPDLHKPGSDDVPRSHHQLDADKGISTTAPSTPRSSWNDTLLANKSGVLGTLYNNSLSLGSNAHPIVVVAPSSSERGASDGRGSLELGSSAAPQEDGLAAYSAALNITIVIGCSLLILNVLIFAVVYYQKDKTRHHHHHHHNGHHEPGMCNNDSNSSFNSSTPNNSYSATIKKRQENGGPITNLCSAGGATELLQIIDNRSNIQVPSILKKPSPSQLLVLEPPYSQHTLPYRHHGAHAKQMAEFSCSTLPRAPLPAKVPKVPDPNPGGGGCGPPAESQPLLVDRSKHSNKIDELRV", "md5" : "6faea26c70037dca84fe5a2c34251a51", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 661, "end" : 698, "location-fragments" : [ { "start" : 661, "end" : 698, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 533, "end" : 554, "location-fragments" : [ { "start" : 533, "end" : 554, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 672, "end" : 698, "location-fragments" : [ { "start" : 672, "end" : 698, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS00941", "name" : "CARBOXYLESTERASE_B_2", "description" : "Carboxylesterases type-B signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019819", "name" : "Carboxylesterase_B_CS", "description" : "Carboxylesterase type B, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 21, "end" : 31, "level" : "STRONG", "cigarAlignment" : "9M1I1M", "alignment" : "EDCLYLNIYaP", "location-fragments" : [ { "start" : 21, "end" : 31, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00941" }, { "signature" : { "accession" : "PF00135", "name" : "COesterase", "description" : "Carboxylesterase family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002018", "name" : "CarbesteraseB", "description" : "Carboxylesterase, type B", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 16, "end" : 521, "hmmStart" : 79, "hmmEnd" : 515, "hmmLength" : 515, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 9.1E-115, "score" : 384.5, "envelopeStart" : 5, "envelopeEnd" : 521, "postProcessed" : true, "location-fragments" : [ { "start" : 16, "end" : 521, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-116, "score" : 389.0, "model-ac" : "PF00135" }, { "signature" : { "accession" : "PTHR43903", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 666, "hmmStart" : 90, "hmmEnd" : 677, "hmmLength" : 746, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 708, "location-fragments" : [ { "start" : 1, "end" : 666, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-220, "familyName" : "GH07829P", "score" : 736.4, "model-ac" : "PTHR43903" }, { "signature" : { "accession" : "PTHR43903:SF16", "name" : "GH07829P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 666, "hmmStart" : 90, "hmmEnd" : 677, "hmmLength" : 746, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 708, "location-fragments" : [ { "start" : 1, "end" : 666, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-220, "familyName" : "GH07829P", "score" : 736.4, "model-ac" : "PTHR43903:SF16" }, { "signature" : { "accession" : "SSF53474", "name" : "alpha/beta-Hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 16, "end" : 530, "hmmLength" : 579, "location-fragments" : [ { "start" : 298, "end" : 530, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 16, "end" : 247, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.95E-96, "model-ac" : "0045186" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 779, "end" : 793, "location-fragments" : [ { "start" : 779, "end" : 793, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 779, "end" : 820, "location-fragments" : [ { "start" : 779, "end" : 820, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910015.1 PREDICTED: neuroligin-4, Y-linked-like [Bemisia tabaci]", "id" : "XP_018910015.1" } ] },{ "sequence" : "MHLKLRHFLSLSNCVMDSASRIMTKECDVKFISLCSGIAVSVVAALSFILWPWICKFVISLKLPLTPTSDTYAIWRDTPIPMHIDFYFFNWTNPHELLDPEKKPEFVQMGPYRFIETKEKVNITWNVNHTVSYQQRKWWYFDAENSKGKLTDNITTLNVVALAASNTVKNWAYVMQSALSTAMSQTSQNISVTKPAGQLLFDGYEDKLIDLAMNFPSMITVPYDKFGWFYTRNGSAEFDGYFNIDVGSEDIEDFGRIRNWNYASRTDYYSGECGELRGSGGELFPPDMQQTKITLFSPDMCRSVILEYERTVEHSGMEGYRFVGGLDMVDNGTHDAANECLCDGECVPQGLSNATSCRYGVPAFISYPHFYLADPVYREDIRGMRPDKDLHQFQMTFEPTTGVPLEVKARLQINILLTANPSVMLFEKVPSIFFPMIWFENKATITEELAEEVKLALYIFENGRYGAAMVLFLGITLILITLVVQRIFENPQDVRKSTQFSLCPQ", "md5" : "c1715ffe3cb590ed14c39bb8cc036cc1", "matches" : [ { "signature" : { "accession" : "PF01130", "name" : "CD36", "description" : "CD36 family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002159", "name" : "CD36_fam", "description" : "CD36 family", "type" : "FAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 39, "end" : 483, "hmmStart" : 5, "hmmEnd" : 463, "hmmLength" : 465, "hmmBounds" : "INCOMPLETE", "evalue" : 1.0E-150, "score" : 502.4, "envelopeStart" : 34, "envelopeEnd" : 485, "postProcessed" : true, "location-fragments" : [ { "start" : 39, "end" : 483, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-151, "score" : 502.6, "model-ac" : "PF01130" }, { "signature" : { "accession" : "PTHR11923:SF93", "name" : "PROTEIN PESTE-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 23, "end" : 486, "hmmStart" : 6, "hmmEnd" : 473, "hmmLength" : 501, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 16, "envelopeEnd" : 502, "location-fragments" : [ { "start" : 23, "end" : 486, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-167, "familyName" : "PROTEIN PESTE-RELATED", "score" : 559.0, "model-ac" : "PTHR11923:SF93" }, { "signature" : { "accession" : "PR01609", "name" : "CD36FAMILY", "description" : "Adhesion molecule CD36 family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002159", "name" : "CD36_fam", "description" : "CD36 family", "type" : "FAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 103, "end" : 115, "pvalue" : 3.5E-4, "score" : 40.05, "motifNumber" : 2, "location-fragments" : [ { "start" : 103, "end" : 115, "dc-status" : "CONTINUOUS" } ] }, { "start" : 393, "end" : 414, "pvalue" : 2.05E-9, "score" : 38.4, "motifNumber" : 6, "location-fragments" : [ { "start" : 393, "end" : 414, "dc-status" : "CONTINUOUS" } ] }, { "start" : 273, "end" : 297, "pvalue" : 9.92E-6, "score" : 26.34, "motifNumber" : 4, "location-fragments" : [ { "start" : 273, "end" : 297, "dc-status" : "CONTINUOUS" } ] }, { "start" : 346, "end" : 370, "pvalue" : 1.97E-11, "score" : 39.72, "motifNumber" : 5, "location-fragments" : [ { "start" : 346, "end" : 370, "dc-status" : "CONTINUOUS" } ] }, { "start" : 77, "end" : 98, "pvalue" : 2.77E-10, "score" : 38.09, "motifNumber" : 1, "location-fragments" : [ { "start" : 77, "end" : 98, "dc-status" : "CONTINUOUS" } ] }, { "start" : 130, "end" : 149, "pvalue" : 5.39E-7, "score" : 35.0, "motifNumber" : 3, "location-fragments" : [ { "start" : 130, "end" : 149, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-38, "graphscan" : "IIIiII", "model-ac" : "PR01609" }, { "signature" : { "accession" : "PTHR11923", "name" : "SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR002159", "name" : "CD36_fam", "description" : "CD36 family", "type" : "FAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 23, "end" : 486, "hmmStart" : 6, "hmmEnd" : 473, "hmmLength" : 501, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 16, "envelopeEnd" : 502, "location-fragments" : [ { "start" : 23, "end" : 486, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-167, "familyName" : "PROTEIN PESTE-RELATED", "score" : 559.0, "model-ac" : "PTHR11923" } ], "xref" : [ { "name" : "XP_018910296.1 PREDICTED: protein croquemort-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910296.1" } ] },{ "sequence" : "MCDKGSSSGCFFTRKGRETQVDLATSPRRQPQINNTNMGPRPKDPLPMVVQGDFRKVSGISNEIFRQIETIENELDGSIAAALASVERRGEMVVRMLDYRSMGKNAAELAKRFLSMQDAQHSVHFVEIVKRPGQTLGLYIREGNGVDRADGVFISRIALESAVYNSGCLKVGDEILAVNLVDVTRMSLDDVVIIMSIPRRLVLATRQVKGLRQAQGTPSQPRALELKVPPVVVIKKSLTREEDQDDEEDEENNHRFADLNRESKIRGRVGQSRSHLALGSLDTNGDIGSGALYYNSRPHAATLDRRMGNSDNKSWSYQPPPPPVVTQQPKPQHFQPFDKSYPNTLESLAEKVHPFNPGNGPGSSYGAGSSRYATTGRSSSRLSNRGPSMPRSGSDQHLPRVEYDYGNGLPARHSGSLLRSSLRASTGMGGSYSRSRDQYNASPSSTLLPRRQRPALDYASDTEATCSSSSRASYYYCRPSPPVSSLTRGVSFRSNSLPRHSLTSQSSGRTPLSVRFERNNLLDEGDSDGALSAPELPIARKHRGRLSSTPSVFTSDEYRAWLSRTPSTSAIYDRLRAGQQKAQRFTFSAENLPERTRQSELLASYRSSGLSALTGLSGLTSSTLDRHTLANRTTSLRRMRHLLELEAKHQADRAKIMEINPAEFLKYKMEKWNGPEPVGASGLLWVHLLAGRGLRNPSPSQTTGNRDLYCVLECDRVHKARTVVRTGDLVFDWDETFELDLVGNKQLDFLIYSWDPQYRHKLCYKGSVHLASLLRDSPIHQLALKIEPRGTLYLRLRHTSPYRTFLRQSRSATGLFGGDLEATVAREGGSIPIIVRRCVEEVERRGLDIIGLYRLCGSATKKRILREAFERNARIVDLSPDHVPDINVITGVLKDYLRELPEPLFTKCLYQMMVDALTVCLPDDPEGNAKLMFSILDCLPRINKATLVFLLDHLAMVVGASGRNKMCSGSVASCLAPVLILHSESATDPMDFMQPISVLRYLLDIWPNKSDSSGLSGTSSPALKMLTPSAASSIASKAGRFSPDIWTSRSRFSNK", "md5" : "3260833966f9ac5dea1857807382cfce", "matches" : [ { "signature" : { "accession" : "G3DSA:2.30.42.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036034", "name" : "PDZ_sf", "description" : "PDZ superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 110, "end" : 224, "hmmStart" : 20, "hmmEnd" : 108, "hmmLength" : 128, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-16, "score" : 62.0, "envelopeStart" : 110, "envelopeEnd" : 224, "postProcessed" : true, "location-fragments" : [ { "start" : 110, "end" : 224, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.1E-17, "score" : 63.0, "model-ac" : "1uf1A00" }, { "signature" : { "accession" : "PF00620", "name" : "RhoGAP", "description" : "RhoGAP domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 832, "end" : 985, "hmmStart" : 1, "hmmEnd" : 149, "hmmLength" : 152, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.3E-37, "score" : 127.0, "envelopeStart" : 832, "envelopeEnd" : 988, "postProcessed" : true, "location-fragments" : [ { "start" : 832, "end" : 985, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-37, "score" : 128.0, "model-ac" : "PF00620" }, { "signature" : { "accession" : "G3DSA:2.60.40.150", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR035892", "name" : "C2_domain_sf", "description" : "C2 domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 680, "end" : 804, "hmmStart" : 6, "hmmEnd" : 126, "hmmLength" : 143, "hmmBounds" : "COMPLETE", "evalue" : 6.0E-11, "score" : 44.5, "envelopeStart" : 680, "envelopeEnd" : 804, "postProcessed" : true, "location-fragments" : [ { "start" : 680, "end" : 804, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-11, "score" : 45.4, "model-ac" : "4npkA01" }, { "signature" : { "accession" : "PS50238", "name" : "RHOGAP", "description" : "Rho GTPase-activating proteins domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 818, "end" : 1010, "score" : 38.893, "alignment" : "GDLEATVAREGGSIPIIVRRCVEEVERRGLDIIGLYRLCGSATKKRILREAFERNARIVDLSPDhvpDINVITGVLKDYLRELPEPLFTKCLYQMMVDaltVCLPDDPEGNAKLMFSILDCLPRINKATLVFLLDHLAMVVGASGRNKMCSGSVASCLAPVLILHSE-SATDPMDFMQPISVLRYLLDIWPNKS", "location-fragments" : [ { "start" : 818, "end" : 1010, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50238" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 497, "end" : 520, "location-fragments" : [ { "start" : 497, "end" : 520, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 427, "end" : 449, "location-fragments" : [ { "start" : 427, "end" : 449, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00239", "name" : "C2_3c", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000008", "name" : "C2_dom", "description" : "C2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 683, "end" : 782, "hmmStart" : 1, "hmmEnd" : 92, "hmmLength" : 92, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-4, "score" : 30.1, "location-fragments" : [ { "start" : 683, "end" : 782, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-4, "score" : 30.1, "model-ac" : "SM00239" }, { "signature" : { "accession" : "G3DSA:1.10.555.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR008936", "name" : "Rho_GTPase_activation_prot", "description" : "Rho GTPase activation protein", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 814, "end" : 1012, "hmmStart" : 3, "hmmEnd" : 191, "hmmLength" : 208, "hmmBounds" : "COMPLETE", "evalue" : 7.3E-50, "score" : 171.0, "envelopeStart" : 814, "envelopeEnd" : 1012, "postProcessed" : true, "location-fragments" : [ { "start" : 814, "end" : 1012, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-50, "score" : 171.8, "model-ac" : "4u3kA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 497, "end" : 514, "location-fragments" : [ { "start" : 497, "end" : 514, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00228", "name" : "pdz_new", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 134, "end" : 209, "hmmStart" : 1, "hmmEnd" : 80, "hmmLength" : 80, "hmmBounds" : "COMPLETE", "evalue" : 4.7E-8, "score" : 42.7, "location-fragments" : [ { "start" : 134, "end" : 209, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-8, "score" : 42.7, "model-ac" : "SM00228" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 362, "end" : 391, "location-fragments" : [ { "start" : 362, "end" : 391, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 253, "end" : 268, "location-fragments" : [ { "start" : 253, "end" : 268, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 303, "end" : 407, "location-fragments" : [ { "start" : 303, "end" : 407, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 39, "location-fragments" : [ { "start" : 19, "end" : 39, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR46150:SF3", "name" : "RHO GTPASE-ACTIVATING PROTEIN 100F", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 47, "end" : 1027, "hmmStart" : 6, "hmmEnd" : 972, "hmmLength" : 1027, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 38, "envelopeEnd" : 1054, "location-fragments" : [ { "start" : 47, "end" : 1027, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "RHO GTPASE-ACTIVATING PROTEIN 100F", "score" : 1135.1, "model-ac" : "PTHR46150:SF3" }, { "signature" : { "accession" : "SM00324", "name" : "RhoGAP_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 829, "end" : 1007, "hmmStart" : 1, "hmmEnd" : 193, "hmmLength" : 193, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-40, "score" : 148.9, "location-fragments" : [ { "start" : 829, "end" : 1007, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-40, "score" : 148.9, "model-ac" : "SM00324" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 40, "location-fragments" : [ { "start" : 18, "end" : 40, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00595", "name" : "PDZ", "description" : "PDZ domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 129, "end" : 196, "hmmStart" : 5, "hmmEnd" : 71, "hmmLength" : 82, "hmmBounds" : "INCOMPLETE", "evalue" : 2.2E-10, "score" : 40.7, "envelopeStart" : 126, "envelopeEnd" : 204, "postProcessed" : true, "location-fragments" : [ { "start" : 129, "end" : 196, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-10, "score" : 41.6, "model-ac" : "PF00595" }, { "signature" : { "accession" : "cd00992", "name" : "PDZ_signaling", "description" : "PDZ_signaling", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 123, "end" : 203, "sites" : [ { "description" : "protein binding site", "numLocations" : 9, "siteLocations" : [ { "start" : 138, "end" : 138, "residue" : "L" }, { "start" : 137, "end" : 137, "residue" : "G" }, { "start" : 140, "end" : 140, "residue" : "I" }, { "start" : 136, "end" : 136, "residue" : "L" }, { "start" : 195, "end" : 195, "residue" : "M" }, { "start" : 191, "end" : 191, "residue" : "V" }, { "start" : 194, "end" : 194, "residue" : "I" }, { "start" : 135, "end" : 135, "residue" : "T" }, { "start" : 192, "end" : 192, "residue" : "V" } ] } ], "evalue" : 7.49619E-15, "score" : 68.7474, "location-fragments" : [ { "start" : 123, "end" : 203, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00992" }, { "signature" : { "accession" : "SSF49562", "name" : "C2 domain (Calcium/lipid-binding domain, CaLB)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 681, "end" : 799, "hmmLength" : 136, "location-fragments" : [ { "start" : 681, "end" : 799, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-16, "model-ac" : "0038166" }, { "signature" : { "accession" : "PS50106", "name" : "PDZ", "description" : "PDZ domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 125, "end" : 195, "score" : 13.692, "alignment" : "FVEIVKRPGQTLGLYIREGNGVDRADGVFISRIALESAVYNSGCLKVGDEILAVNLVDVTRMSLDDVVIIM---------------", "location-fragments" : [ { "start" : 125, "end" : 195, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50106" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 237, "end" : 268, "location-fragments" : [ { "start" : 237, "end" : 268, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00030", "name" : "C2", "description" : "C2", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 684, "end" : 786, "sites" : [ ], "evalue" : 1.67481E-10, "score" : 57.0767, "location-fragments" : [ { "start" : 684, "end" : 786, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00030" }, { "signature" : { "accession" : "SSF50156", "name" : "PDZ domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036034", "name" : "PDZ_sf", "description" : "PDZ superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 118, "end" : 198, "hmmLength" : 124, "location-fragments" : [ { "start" : 118, "end" : 198, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.72E-16, "model-ac" : "0050541" }, { "signature" : { "accession" : "SSF48350", "name" : "GTPase activation domain, GAP", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR008936", "name" : "Rho_GTPase_activation_prot", "description" : "Rho GTPase activation protein", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 815, "end" : 1006, "hmmLength" : 196, "location-fragments" : [ { "start" : 815, "end" : 1006, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.22E-44, "model-ac" : "0050892" }, { "signature" : { "accession" : "PTHR46150", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 47, "end" : 1027, "hmmStart" : 6, "hmmEnd" : 972, "hmmLength" : 1027, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 38, "envelopeEnd" : 1054, "location-fragments" : [ { "start" : 47, "end" : 1027, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "RHO GTPASE-ACTIVATING PROTEIN 100F", "score" : 1135.1, "model-ac" : "PTHR46150" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 427, "end" : 462, "location-fragments" : [ { "start" : 427, "end" : 462, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910341.1 PREDICTED: rho GTPase-activating protein 100F-like isoform X4 [Bemisia tabaci]", "id" : "XP_018910341.1" } ] },{ "sequence" : "MAEIKDKRLPIDFWKELPDASMPEILESSVFQDLIHNENKFDLVFMEVFFGQEPLVVLGHLLDAPVVAFATFGHMPDILRYMGAPNAVAYLSHFNVDYAGSLILTQRLENAWIHYRTTLYDEYWYYPQHDAVLAKYFPGPLPSISDMLRNISLFFLTANTAVDGAKLYPPNVIELPVLHLKDPAPLDKELDVIMNNAQDGVIYFSFGSIVTPSILGEEETQIFLSVLKELNQTVLWKTDWNSTAHDIPKNVYTRDWFDQKSILAHPRCVLFLTHGGLSSLMEAINYAVPVVGMSVFGDQPKNLAYAEYLGYGLHIPHKDLTQNSLRRALRTVLQDGRFKENINRASKIFQDKPMSSLDTAIYWIEYAIRHKGAHHLKPLAVRMPWYQLFLLDIITVCFTIFVVLSYLMFKMISLLLRKYFTRSRPLKEKSN", "md5" : "6c591b0797eb0d32c116eae81f668fc6", "matches" : [ { "signature" : { "accession" : "PF00201", "name" : "UDPGT", "description" : "UDP-glucoronosyl and UDP-glucosyl transferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002213", "name" : "UDP_glucos_trans", "description" : "UDP-glucuronosyl/UDP-glucosyltransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "UDP-glycosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008194" } ], "pathwayXRefs" : [ { "name" : "Glucuronidation", "databaseName" : "Reactome", "id" : "R-HSA-156588" } ] } }, "locations" : [ { "start" : 37, "end" : 420, "hmmStart" : 115, "hmmEnd" : 493, "hmmLength" : 499, "hmmBounds" : "INCOMPLETE", "evalue" : 1.2E-65, "score" : 222.2, "envelopeStart" : 24, "envelopeEnd" : 424, "postProcessed" : true, "location-fragments" : [ { "start" : 37, "end" : 420, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.2E-66, "score" : 222.6, "model-ac" : "PF00201" }, { "signature" : { "accession" : "cd03784", "name" : "GT1_Gtf-like", "description" : "GT1_Gtf-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 361, "sites" : [ { "description" : "TDP-binding site", "numLocations" : 5, "siteLocations" : [ { "start" : 276, "end" : 276, "residue" : "G" }, { "start" : 278, "end" : 278, "residue" : "S" }, { "start" : 274, "end" : 274, "residue" : "H" }, { "start" : 279, "end" : 279, "residue" : "S" }, { "start" : 208, "end" : 208, "residue" : "S" } ] } ], "evalue" : 2.95419E-51, "score" : 175.817, "location-fragments" : [ { "start" : 1, "end" : 361, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd03784" }, { "signature" : { "accession" : "SSF53756", "name" : "UDP-Glycosyltransferase/glycogen phosphorylase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 32, "end" : 373, "hmmLength" : 473, "location-fragments" : [ { "start" : 32, "end" : 373, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-77, "model-ac" : "0054538" }, { "signature" : { "accession" : "G3DSA:3.40.50.2000", "name" : "Glycogen Phosphorylase B;", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 181, "end" : 351, "hmmStart" : 5, "hmmEnd" : 169, "hmmLength" : 170, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-45, "score" : 156.9, "envelopeStart" : 181, "envelopeEnd" : 351, "postProcessed" : true, "location-fragments" : [ { "start" : 181, "end" : 351, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.0E-46, "score" : 157.5, "model-ac" : "2o6lB00" }, { "signature" : { "accession" : "PTHR11926", "name" : "GLUCOSYL/GLUCURONOSYL TRANSFERASES", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 191, "end" : 303, "hmmStart" : 47, "hmmEnd" : 126, "hmmLength" : 134, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 405, "location-fragments" : [ { "start" : 191, "end" : 303, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-14, "familyName" : "GLUCOSYL/GLUCURONOSYL TRANSFERASES", "score" : 55.6, "model-ac" : "PTHR11926" } ], "xref" : [ { "name" : "XP_018910403.1 PREDICTED: UDP-glucuronosyltransferase 2B14-like isoform X4 [Bemisia tabaci]", "id" : "XP_018910403.1" } ] },{ "sequence" : "MPSGLGASYRSLADDVYRSTTISERDKFSVLESVKKAFNFTSFSAQALTRRSEPLISRSESSQPVVSNRKMPTFAASEEASLLGAMPSDSMDDIELQNVQLQFPSARSLSREGSDVEEIKVETDRGHLLVAVQGNRSKPAIVTYHDLGLNYVSSFQAFFNYLDMRQLLNNFSVYHVNAPGQEEGAPPFPDDYEYPTMDDLAAQLNFVLTHFGLRSIIGLGVGAGGNILARFALSNPDKVEALCLINVVSTAAGWIEWGYQKLNARYLRSKGMTQGVLDYLMWHHFGRGTEERNHDLVQVYRNYFERCVNPGNLALFIDSYIRRTDLNIERDPDPNRRKEGGGSPTLSMPVMNITGSLSPHVNDTVTLNSRLDPSNSSWMKISDCGMVLEEQPNKVCEALRLFLQGLGYAVKLGRPKITNSTSAEAFIVMSVKTSRSLDSVRSAPWSIRITENPISETAAC", "md5" : "b1e1848b2e85c6400342f2dfaaa79237", "matches" : [ { "signature" : { "accession" : "G3DSA:3.40.50.1820", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 109, "end" : 405, "hmmStart" : 9, "hmmEnd" : 286, "hmmLength" : 286, "hmmBounds" : "COMPLETE", "evalue" : 4.5E-93, "score" : 313.8, "envelopeStart" : 109, "envelopeEnd" : 405, "postProcessed" : true, "location-fragments" : [ { "start" : 109, "end" : 405, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-93, "score" : 314.2, "model-ac" : "2qmqA00" }, { "signature" : { "accession" : "SSF53474", "name" : "alpha/beta-Hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 116, "end" : 404, "hmmLength" : 281, "location-fragments" : [ { "start" : 116, "end" : 404, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-26, "model-ac" : "0046077" }, { "signature" : { "accession" : "PF03096", "name" : "Ndr", "description" : "Ndr family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004142", "name" : "NDRG", "description" : "NDRG", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 120, "end" : 408, "hmmStart" : 3, "hmmEnd" : 281, "hmmLength" : 283, "hmmBounds" : "INCOMPLETE", "evalue" : 2.3E-103, "score" : 344.8, "envelopeStart" : 118, "envelopeEnd" : 410, "postProcessed" : true, "location-fragments" : [ { "start" : 120, "end" : 408, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-103, "score" : 345.2, "model-ac" : "PF03096" }, { "signature" : { "accession" : "PTHR11034:SF19", "name" : "GH09802P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 119, "end" : 417, "hmmStart" : 3, "hmmEnd" : 294, "hmmLength" : 301, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 29, "envelopeEnd" : 428, "location-fragments" : [ { "start" : 119, "end" : 417, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-128, "familyName" : "GH09802P", "score" : 429.3, "model-ac" : "PTHR11034:SF19" }, { "signature" : { "accession" : "PTHR11034", "name" : "N-MYC DOWNSTREAM REGULATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR004142", "name" : "NDRG", "description" : "NDRG", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 119, "end" : 417, "hmmStart" : 3, "hmmEnd" : 294, "hmmLength" : 301, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 29, "envelopeEnd" : 428, "location-fragments" : [ { "start" : 119, "end" : 417, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-128, "familyName" : "GH09802P", "score" : 429.3, "model-ac" : "PTHR11034" } ], "xref" : [ { "name" : "XP_018910060.1 PREDICTED: protein NDRG3 isoform X1 [Bemisia tabaci]", "id" : "XP_018910060.1" } ] },{ "sequence" : "MDSNLSDLHPDNRIKKLAEEAEPQVDFTIPARRYFRSGKEMVRMATVYYDEGKLEEAYKIYLRFSILFLDKIKGHPEFNTKNEDFKDIKEKLQTAIPRAEELKNKLLKKYKIEYEAHLQNVRQKEQQQLKAQQRPQPVAPQMKPQSAPAERRLTAGKSDLSNQVAIVPALPDDDILYPPPLTVQVPSEKPLFDRSNKPASLLNSQPLRHGLRPVIVPAKLIHEFLVLADRNTISNKETCGILAGKLSQDKLVITHLLVPEQNGTPDSCTTQNEEALFAFQDKFDLITLGWIHTHPTQTAFLSSVDLHTHCSYQLMMPEALAIVCAPRYDNYRCFCLTHDYGLRYIANCPIKNGFHPHPSEPPLFMEAEHAIVDDQSFIHVVDLRK", "md5" : "c7faff51e962ba403aa7a7c78b95fcff", "matches" : [ { "signature" : { "accession" : "PF08969", "name" : "USP8_dimer", "description" : "USP8 dimerisation domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR015063", "name" : "USP8_dimer", "description" : "USP8 dimerisation domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5, "end" : 111, "hmmStart" : 3, "hmmEnd" : 112, "hmmLength" : 114, "hmmBounds" : "INCOMPLETE", "evalue" : 7.5E-21, "score" : 74.4, "envelopeStart" : 3, "envelopeEnd" : 113, "postProcessed" : true, "location-fragments" : [ { "start" : 5, "end" : 111, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-21, "score" : 75.3, "model-ac" : "PF08969" }, { "signature" : { "accession" : "SSF102712", "name" : "JAB1/MPN domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 214, "end" : 342, "hmmLength" : 121, "location-fragments" : [ { "start" : 214, "end" : 342, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.35E-18, "model-ac" : "0048572" }, { "signature" : { "accession" : "PTHR12947", "name" : "AMSH", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 127, "end" : 384, "hmmStart" : 272, "hmmEnd" : 496, "hmmLength" : 497, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 123, "envelopeEnd" : 385, "location-fragments" : [ { "start" : 127, "end" : 384, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3, "end" : 143, "hmmStart" : 3, "hmmEnd" : 137, "hmmLength" : 497, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 164, "location-fragments" : [ { "start" : 3, "end" : 143, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-107, "familyName" : "REGULATOR OF FREE UBIQUITIN CHAINS 1", "score" : 363.8, "model-ac" : "PTHR12947" }, { "signature" : { "accession" : "G3DSA:3.40.140.10", "name" : "Cytidine Deaminase", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 195, "end" : 385, "hmmStart" : 19, "hmmEnd" : 195, "hmmLength" : 197, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-65, "score" : 222.0, "envelopeStart" : 195, "envelopeEnd" : 385, "postProcessed" : true, "location-fragments" : [ { "start" : 195, "end" : 385, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-65, "score" : 222.7, "model-ac" : "4jxeB00" }, { "signature" : { "accession" : "G3DSA:1.20.58.280", "name" : "Hypothetical protein 1500032h18.", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 138, "hmmStart" : 8, "hmmEnd" : 136, "hmmLength" : 146, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-38, "score" : 133.4, "envelopeStart" : 2, "envelopeEnd" : 138, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 138, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.9E-39, "score" : 134.2, "model-ac" : "2xzeB00" }, { "signature" : { "accession" : "SSF140856", "name" : "USP8 N-terminal domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 4, "end" : 127, "hmmLength" : 134, "location-fragments" : [ { "start" : 4, "end" : 127, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.37E-13, "model-ac" : "0051729" }, { "signature" : { "accession" : "PS50249", "name" : "MPN", "description" : "MPN domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR037518", "name" : "MPN", "description" : "MPN domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 214, "end" : 343, "score" : 26.203, "alignment" : "VIVPAKLIHEFlVLADRnTISNKETCGILAGKLSqD-KLVITHLLVPEQNGTPDSCTTQNEEALFAFQDKFDLITLGWIHTHPTQTAFLSSVDLHTHCSYQLMMPEALAIVCAPRYDNYRCFCLTHDYGLR", "location-fragments" : [ { "start" : 214, "end" : 343, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50249" }, { "signature" : { "accession" : "cd08066", "name" : "MPN_AMSH_like", "description" : "MPN_AMSH_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 211, "end" : 384, "sites" : [ { "description" : "Proximal ubiquitin recognition interface", "numLocations" : 10, "siteLocations" : [ { "start" : 302, "end" : 302, "residue" : "S" }, { "start" : 297, "end" : 297, "residue" : "Q" }, { "start" : 300, "end" : 300, "residue" : "F" }, { "start" : 266, "end" : 266, "residue" : "D" }, { "start" : 303, "end" : 303, "residue" : "S" }, { "start" : 354, "end" : 354, "residue" : "F" }, { "start" : 298, "end" : 298, "residue" : "T" }, { "start" : 356, "end" : 356, "residue" : "P" }, { "start" : 294, "end" : 294, "residue" : "H" }, { "start" : 355, "end" : 355, "residue" : "H" } ] }, { "description" : "Zinc-binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 292, "end" : 292, "residue" : "H" }, { "start" : 305, "end" : 305, "residue" : "D" }, { "start" : 294, "end" : 294, "residue" : "H" } ] }, { "description" : "Distal ubiquitin recognition interface", "numLocations" : 27, "siteLocations" : [ { "start" : 280, "end" : 280, "residue" : "Q" }, { "start" : 292, "end" : 292, "residue" : "H" }, { "start" : 314, "end" : 314, "residue" : "L" }, { "start" : 312, "end" : 312, "residue" : "Y" }, { "start" : 240, "end" : 240, "residue" : "G" }, { "start" : 239, "end" : 239, "residue" : "C" }, { "start" : 267, "end" : 267, "residue" : "S" }, { "start" : 290, "end" : 290, "residue" : "W" }, { "start" : 305, "end" : 305, "residue" : "D" }, { "start" : 315, "end" : 315, "residue" : "M" }, { "start" : 308, "end" : 308, "residue" : "T" }, { "start" : 277, "end" : 277, "residue" : "F" }, { "start" : 294, "end" : 294, "residue" : "H" }, { "start" : 273, "end" : 273, "residue" : "E" }, { "start" : 302, "end" : 302, "residue" : "S" }, { "start" : 268, "end" : 268, "residue" : "C" }, { "start" : 311, "end" : 311, "residue" : "S" }, { "start" : 287, "end" : 287, "residue" : "T" }, { "start" : 354, "end" : 354, "residue" : "F" }, { "start" : 241, "end" : 241, "residue" : "I" }, { "start" : 304, "end" : 304, "residue" : "V" }, { "start" : 307, "end" : 307, "residue" : "H" }, { "start" : 270, "end" : 270, "residue" : "T" }, { "start" : 266, "end" : 266, "residue" : "D" }, { "start" : 274, "end" : 274, "residue" : "E" }, { "start" : 269, "end" : 269, "residue" : "T" }, { "start" : 286, "end" : 286, "residue" : "I" } ] }, { "description" : "MPN+ (JAMM) motif", "numLocations" : 5, "siteLocations" : [ { "start" : 292, "end" : 292, "residue" : "H" }, { "start" : 302, "end" : 302, "residue" : "S" }, { "start" : 305, "end" : 305, "residue" : "D" }, { "start" : 237, "end" : 237, "residue" : "E" }, { "start" : 294, "end" : 294, "residue" : "H" } ] } ], "evalue" : 4.60026E-109, "score" : 315.304, "location-fragments" : [ { "start" : 211, "end" : 384, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd08066" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 123, "end" : 155, "location-fragments" : [ { "start" : 123, "end" : 155, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 89, "end" : 127, "location-fragments" : [ { "start" : 89, "end" : 127, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF01398", "name" : "JAB", "description" : "JAB1/Mov34/MPN/PAD-1 ubiquitin protease", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000555", "name" : "JAMM/MPN+_dom", "description" : "JAB1/MPN/MOV34 metalloenzyme domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "metallopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008237" }, { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" }, { "name" : "isopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0070122" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 212, "end" : 317, "hmmStart" : 4, "hmmEnd" : 117, "hmmLength" : 118, "hmmBounds" : "INCOMPLETE", "evalue" : 2.2E-17, "score" : 63.1, "envelopeStart" : 209, "envelopeEnd" : 318, "postProcessed" : true, "location-fragments" : [ { "start" : 212, "end" : 317, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-17, "score" : 64.1, "model-ac" : "PF01398" }, { "signature" : { "accession" : "PTHR12947:SF4", "name" : "REGULATOR OF FREE UBIQUITIN CHAINS 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 143, "hmmStart" : 3, "hmmEnd" : 137, "hmmLength" : 497, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 164, "location-fragments" : [ { "start" : 3, "end" : 143, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-107, "familyName" : "REGULATOR OF FREE UBIQUITIN CHAINS 1", "score" : 363.8, "model-ac" : "PTHR12947:SF4" }, { "signature" : { "accession" : "SM00232", "name" : "pad1_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000555", "name" : "JAMM/MPN+_dom", "description" : "JAB1/MPN/MOV34 metalloenzyme domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "metallopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008237" }, { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" }, { "name" : "isopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0070122" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 213, "end" : 339, "hmmStart" : 1, "hmmEnd" : 156, "hmmLength" : 156, "hmmBounds" : "COMPLETE", "evalue" : 3.2E-9, "score" : 46.6, "location-fragments" : [ { "start" : 213, "end" : 339, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-9, "score" : 46.6, "model-ac" : "SM00232" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 123, "end" : 140, "location-fragments" : [ { "start" : 123, "end" : 140, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12947:SF4", "name" : "REGULATOR OF FREE UBIQUITIN CHAINS 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 127, "end" : 384, "hmmStart" : 272, "hmmEnd" : 496, "hmmLength" : 497, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 123, "envelopeEnd" : 385, "location-fragments" : [ { "start" : 127, "end" : 384, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-107, "familyName" : "REGULATOR OF FREE UBIQUITIN CHAINS 1", "score" : 363.8, "model-ac" : "PTHR12947:SF4" } ], "xref" : [ { "name" : "XP_018910178.1 PREDICTED: STAM-binding protein isoform X2 [Bemisia tabaci]", "id" : "XP_018910178.1" } ] },{ "sequence" : "MLARISVVLNRTEWACAQSQVRCFKMAATGYQNGTGGTGKPQLSQWFIDRESKYGAHNYHPLPVVINKAEGVYMWDVEGKKYYDFLSAYSAVNQGHSHPKILEALAEQAKTLALTSRAFYNNVLGEYEEYMTKIFGYDKLLPMNTGVEGGETACKLARKWGYLKKKIPENQAKIIFAEGNFWGRTLAAISSSTDPSSYAGFGPYMPGYNIVPYNNLEALEVSDIPRLQSPHIFCLVDIFVERKRIVIACL", "md5" : "c6c3ac0e67f8ea44975a9d2fafbc641a", "matches" : [ { "signature" : { "accession" : "PTHR11986:SF118", "name" : "ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 40, "end" : 222, "hmmStart" : 36, "hmmEnd" : 218, "hmmLength" : 439, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 245, "location-fragments" : [ { "start" : 40, "end" : 222, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-94, "familyName" : "ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL", "score" : 317.8, "model-ac" : "PTHR11986:SF118" }, { "signature" : { "accession" : "PTHR11986", "name" : "AMINOTRANSFERASE CLASS III", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 40, "end" : 222, "hmmStart" : 36, "hmmEnd" : 218, "hmmLength" : 439, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 245, "location-fragments" : [ { "start" : 40, "end" : 222, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-94, "familyName" : "ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL", "score" : 317.8, "model-ac" : "PTHR11986" }, { "signature" : { "accession" : "PF00202", "name" : "Aminotran_3", "description" : "Aminotransferase class-III", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005814", "name" : "Aminotrans_3", "description" : "Aminotransferase class-III", "type" : "FAMILY", "goXRefs" : [ { "name" : "pyridoxal phosphate binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030170" }, { "name" : "transaminase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008483" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 55, "end" : 221, "hmmStart" : 2, "hmmEnd" : 168, "hmmLength" : 403, "hmmBounds" : "INCOMPLETE", "evalue" : 4.6E-41, "score" : 140.9, "envelopeStart" : 54, "envelopeEnd" : 233, "postProcessed" : true, "location-fragments" : [ { "start" : 55, "end" : 221, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.7E-41, "score" : 141.2, "model-ac" : "PF00202" }, { "signature" : { "accession" : "G3DSA:3.40.640.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015421", "name" : "PyrdxlP-dep_Trfase_major", "description" : "Pyridoxal phosphate-dependent transferase, major domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 98, "end" : 237, "hmmStart" : 1, "hmmEnd" : 123, "hmmLength" : 250, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-30, "score" : 107.1, "envelopeStart" : 98, "envelopeEnd" : 237, "postProcessed" : true, "location-fragments" : [ { "start" : 98, "end" : 237, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-30, "score" : 107.5, "model-ac" : "3lg0D02" }, { "signature" : { "accession" : "SSF53383", "name" : "PLP-dependent transferases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR015424", "name" : "PyrdxlP-dep_Trfase", "description" : "Pyridoxal phosphate-dependent transferase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 220, "hmmLength" : 404, "location-fragments" : [ { "start" : 44, "end" : 220, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.04E-46, "model-ac" : "0045392" } ], "xref" : [ { "name" : "XP_018910494.1 PREDICTED: ornithine aminotransferase, mitochondrial-like [Bemisia tabaci]", "id" : "XP_018910494.1" } ] },{ "sequence" : "MSQYYPYKCTPTIYPANPFDANADAEVLRKAMKGFGTDEAAIIEVLGRRGIVQRLEIAEAFKTLYGKDLIDDLKSELSGKFERVILALLTPLPLYYAKELHDAIAGLGTDEGAIIEILCTLSNYGIKTIASFYEKEYEKSLEKDLKGDTSGHFQRLLVSLVQANRDESVDVDQAQVLKDAEDLHAAGVEKSWGTDESVFNSVLATRSYNHLREVFNQYAVIAGHDIEEAISSEFSGSVGKGLLAIAKVVRSKVTYFAERLHDSMAGAGTDDRTLIRIIVSRSEIDLGDIKAAFEEKYGQTLESWIADDVGGDTSSLLQKLLE", "md5" : "14719d90bc5f1b6c58e0b945d6d82aa7", "matches" : [ { "signature" : { "accession" : "PS00223", "name" : "ANNEXIN_1", "description" : "Annexin repeat signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018252", "name" : "Annexin_repeat_CS", "description" : "Annexin repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 268, "end" : 320, "level" : "STRONG", "cigarAlignment" : "2M8I1M2I1M3I1M2I1M4I1M7I1M3I1M5I1M5I1M2I1M", "alignment" : "GTddrtliriIvsRseiDlgDikaaFeekygqtLeswIaddvgGdtsslLqkL", "location-fragments" : [ { "start" : 268, "end" : 320, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00223" }, { "signature" : { "accession" : "G3DSA:1.10.220.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 165, "end" : 251, "hmmStart" : 1, "hmmEnd" : 84, "hmmLength" : 86, "hmmBounds" : "COMPLETE", "evalue" : 3.2E-26, "score" : 93.3, "envelopeStart" : 165, "envelopeEnd" : 251, "postProcessed" : true, "location-fragments" : [ { "start" : 165, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-90, "score" : 298.7, "model-ac" : "1hm6A03" }, { "signature" : { "accession" : "PTHR10502:SF184", "name" : "ANNEXIN B9", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 318, "hmmStart" : 4, "hmmEnd" : 319, "hmmLength" : 324, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 322, "location-fragments" : [ { "start" : 2, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.2E-155, "familyName" : "ANNEXIN B9", "score" : 517.9, "model-ac" : "PTHR10502:SF184" }, { "signature" : { "accession" : "PR00196", "name" : "ANNEXIN", "description" : "Annexin family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001464", "name" : "Annexin", "description" : "Annexin", "type" : "FAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 73, "end" : 89, "pvalue" : 4.98E-11, "score" : 64.27, "motifNumber" : 2, "location-fragments" : [ { "start" : 73, "end" : 89, "dc-status" : "CONTINUOUS" } ] }, { "start" : 264, "end" : 284, "pvalue" : 7.41E-14, "score" : 72.66, "motifNumber" : 5, "location-fragments" : [ { "start" : 264, "end" : 284, "dc-status" : "CONTINUOUS" } ] }, { "start" : 33, "end" : 55, "pvalue" : 8.92E-10, "score" : 51.05, "motifNumber" : 1, "location-fragments" : [ { "start" : 33, "end" : 55, "dc-status" : "CONTINUOUS" } ] }, { "start" : 100, "end" : 121, "pvalue" : 1.8E-10, "score" : 52.53, "motifNumber" : 3, "location-fragments" : [ { "start" : 100, "end" : 121, "dc-status" : "CONTINUOUS" } ] }, { "start" : 184, "end" : 210, "pvalue" : 7.39E-10, "score" : 42.11, "motifNumber" : 4, "location-fragments" : [ { "start" : 184, "end" : 210, "dc-status" : "CONTINUOUS" } ] }, { "start" : 292, "end" : 307, "pvalue" : 1.09E-4, "score" : 33.33, "motifNumber" : 6, "location-fragments" : [ { "start" : 292, "end" : 307, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-50, "graphscan" : "IIIIII.", "model-ac" : "PR00196" }, { "signature" : { "accession" : "PS51897", "name" : "ANNEXIN_2", "description" : "Annexin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 91, "end" : 162, "score" : 27.54, "alignment" : "PLPLYYAKELHDAIAGLGTDEGAIIEILCTLSNYGIKTIASFYEKEYEKSLEKDLKGDTSGHFQRLLVSLVQ", "location-fragments" : [ { "start" : 91, "end" : 162, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51897" }, { "signature" : { "accession" : "PS51897", "name" : "ANNEXIN_2", "description" : "Annexin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 251, "end" : 322, "score" : 23.453, "alignment" : "SKVTYFAERLHDSMAGAGTDDRTLIRIIVSRSEIDLGDIKAAFEEKYGQTLESWIADdvggDTSSLLQKLLE----", "location-fragments" : [ { "start" : 251, "end" : 322, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51897" }, { "signature" : { "accession" : "PS51897", "name" : "ANNEXIN_2", "description" : "Annexin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 174, "end" : 247, "score" : 23.76, "alignment" : "AQVLKDAEDLHAAGVEksWGTDESVFNSVLATRSYNHLREVFNQYAVIAGHDIEEAISSEFSGSVGKGLLAIAK", "location-fragments" : [ { "start" : 174, "end" : 247, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51897" }, { "signature" : { "accession" : "PTHR10502", "name" : "ANNEXIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 318, "hmmStart" : 4, "hmmEnd" : 319, "hmmLength" : 324, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 322, "location-fragments" : [ { "start" : 2, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.2E-155, "familyName" : "ANNEXIN B9", "score" : 517.9, "model-ac" : "PTHR10502" }, { "signature" : { "accession" : "G3DSA:1.10.220.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 253, "end" : 322, "hmmStart" : 3, "hmmEnd" : 69, "hmmLength" : 73, "hmmBounds" : "COMPLETE", "evalue" : 6.2E-23, "score" : 82.5, "envelopeStart" : 253, "envelopeEnd" : 322, "postProcessed" : true, "location-fragments" : [ { "start" : 253, "end" : 322, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-84, "score" : 279.4, "model-ac" : "1n00A03" }, { "signature" : { "accession" : "PF00191", "name" : "Annexin", "description" : "Annexin", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018502", "name" : "Annexin_repeat", "description" : "Annexin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 24, "end" : 88, "hmmStart" : 2, "hmmEnd" : 66, "hmmLength" : 66, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.3E-24, "score" : 84.4, "envelopeStart" : 23, "envelopeEnd" : 88, "postProcessed" : true, "location-fragments" : [ { "start" : 24, "end" : 88, "dc-status" : "CONTINUOUS" } ] }, { "start" : 255, "end" : 319, "hmmStart" : 1, "hmmEnd" : 65, "hmmLength" : 66, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 9.9E-19, "score" : 67.2, "envelopeStart" : 255, "envelopeEnd" : 320, "postProcessed" : true, "location-fragments" : [ { "start" : 255, "end" : 319, "dc-status" : "CONTINUOUS" } ] }, { "start" : 179, "end" : 245, "hmmStart" : 2, "hmmEnd" : 66, "hmmLength" : 66, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.1E-19, "score" : 67.7, "envelopeStart" : 178, "envelopeEnd" : 245, "postProcessed" : true, "location-fragments" : [ { "start" : 179, "end" : 245, "dc-status" : "CONTINUOUS" } ] }, { "start" : 95, "end" : 160, "hmmStart" : 1, "hmmEnd" : 66, "hmmLength" : 66, "hmmBounds" : "COMPLETE", "evalue" : 7.1E-23, "score" : 80.5, "envelopeStart" : 95, "envelopeEnd" : 160, "postProcessed" : true, "location-fragments" : [ { "start" : 95, "end" : 160, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-91, "score" : 299.1, "model-ac" : "PF00191" }, { "signature" : { "accession" : "G3DSA:1.10.220.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 18, "end" : 90, "hmmStart" : 2, "hmmEnd" : 72, "hmmLength" : 73, "hmmBounds" : "COMPLETE", "evalue" : 7.4E-29, "score" : 101.6, "envelopeStart" : 18, "envelopeEnd" : 90, "postProcessed" : true, "location-fragments" : [ { "start" : 18, "end" : 90, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-89, "score" : 294.1, "model-ac" : "1hm6A01" }, { "signature" : { "accession" : "SM00335", "name" : "annex3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR018502", "name" : "Annexin_repeat", "description" : "Annexin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 268, "end" : 320, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 3.5E-16, "score" : 69.8, "location-fragments" : [ { "start" : 268, "end" : 320, "dc-status" : "CONTINUOUS" } ] }, { "start" : 193, "end" : 245, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 3.5E-15, "score" : 66.4, "location-fragments" : [ { "start" : 193, "end" : 245, "dc-status" : "CONTINUOUS" } ] }, { "start" : 36, "end" : 88, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 4.1E-24, "score" : 96.1, "location-fragments" : [ { "start" : 36, "end" : 88, "dc-status" : "CONTINUOUS" } ] }, { "start" : 108, "end" : 160, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-22, "score" : 90.8, "location-fragments" : [ { "start" : 108, "end" : 160, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-92, "score" : 323.1, "model-ac" : "SM00335" }, { "signature" : { "accession" : "PS51897", "name" : "ANNEXIN_2", "description" : "Annexin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 90, "score" : 30.169, "alignment" : "FDANADAEVLRKAMKGFGTDEAAIIEVLGRRGIVQRLEIAEAFKTLYGKDLIDDLKSELSGKFERVILALLT", "location-fragments" : [ { "start" : 19, "end" : 90, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51897" }, { "signature" : { "accession" : "PS00223", "name" : "ANNEXIN_1", "description" : "Annexin repeat signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018252", "name" : "Annexin_repeat_CS", "description" : "Annexin repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 36, "end" : 88, "level" : "STRONG", "cigarAlignment" : "2M8I1M2I1M3I1M2I1M4I1M7I1M3I1M5I1M5I1M2I1M", "alignment" : "GTdeaaiievLgrRgivQrlEiaeaFktlygkdLiddLkselsGkfervIlaL", "location-fragments" : [ { "start" : 36, "end" : 88, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00223" }, { "signature" : { "accession" : "SSF47874", "name" : "Annexin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3, "end" : 321, "hmmLength" : 343, "location-fragments" : [ { "start" : 3, "end" : 321, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-114, "model-ac" : "0038635" }, { "signature" : { "accession" : "G3DSA:1.10.220.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 93, "end" : 164, "hmmStart" : 5, "hmmEnd" : 73, "hmmLength" : 74, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-26, "score" : 94.5, "envelopeStart" : 93, "envelopeEnd" : 164, "postProcessed" : true, "location-fragments" : [ { "start" : 93, "end" : 164, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-92, "score" : 305.0, "model-ac" : "1w3wA02" } ], "xref" : [ { "name" : "XP_018909641.1 PREDICTED: annexin B9 isoform X4 [Bemisia tabaci]", "id" : "XP_018909641.1" } ] },{ "sequence" : "MCALWFFLIYRLRVLIVSVSPSFNLPRLIGLILPDHLVEFDNLVTASFDALALRRWSGFSRFLLVKVSCRECFQLGVGQLDNSPLEHTLRAASRASGLVISTPFNLDYPIIRFTGKRQMKIPRYHLTKERQRTPSIARHAPGGTLVRFELIALPGPRGQ", "md5" : "cdd0d90e9d26fdb5219c1ffbc87d8bd3", "matches" : [ ], "xref" : [ { "name" : "XP_018910522.1 PREDICTED: uncharacterized protein LOC109039486 isoform X1 [Bemisia tabaci]", "id" : "XP_018910522.1" } ] },{ "sequence" : "MNPLYTLGALCFVAVCSAAVSTTEKSALKNDKRSLDSYGGYGGSVGSSYGGSSGGYGSYGGSSLGSSYGGSSLGSSYGSSSLGSSYGSSSLGSSYGGSSLGSGYGSSFNAPALQHGFVPSAGPYGPAISGGSYGGSYGSGYSDASYGSAGISGASYGGASYGGSSFGGASYGGGYEETGPAQLLAKHVHVHKKYGIPVAKPYPVHVTNTVQVPVPQPYPVHVPKPYPVHKPYPVPVRVEKPVPVPVVKHVPVHVPHPVPVPVAKPVPVPVARPVPVPVHKTVQVPHPVPVPVTVHKPVYVQAPAVSHGSGVVCDTSSSIGAGSVGSVGSFGGSYGGASFGSGVGSYGSGFDSGSYGGASLGGASYGGASYGSGYDTGSYGGASLGGASYGGSYGSGAGSLSSYGSHGSIESIGSGASYGGISSGSYGGSYGSGGLESVGGSYGSGASYGGGSSYGGSYGSGASYGGSYGSSGDANAWKND", "md5" : "6155e20cb1072dcbe03685a59b2f0ae4", "matches" : [ { "signature" : { "accession" : "PTHR47771", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 132, "end" : 302, "hmmStart" : 33, "hmmEnd" : 202, "hmmLength" : 207, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 116, "envelopeEnd" : 317, "location-fragments" : [ { "start" : 132, "end" : 302, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-27, "familyName" : "HDC01644", "score" : 97.8, "model-ac" : "PTHR47771" }, { "signature" : { "accession" : "PTHR47771:SF3", "name" : "HDC01644", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 132, "end" : 302, "hmmStart" : 33, "hmmEnd" : 202, "hmmLength" : 207, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 116, "envelopeEnd" : 317, "location-fragments" : [ { "start" : 132, "end" : 302, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-27, "familyName" : "HDC01644", "score" : 97.8, "model-ac" : "PTHR47771:SF3" } ], "xref" : [ { "name" : "XP_018909762.1 PREDICTED: keratin, type I cytoskeletal 9-like [Bemisia tabaci]", "id" : "XP_018909762.1" } ] },{ "sequence" : "MDLLGSILKSMDKPPTINSGVKQQLKKQNEAYLKEKDKERAKLQSFRDSIQKKIHDFAKDDSQQRLKFPPMDQIYRAVIHEIAEDANLSGCSFGEEGIDRYIMVYKKENPPSEDELAVLRRGEEWNEEKAKELAKQRELEKQEEEAAKIRKKEKFVPQHNYKDKYAHLIGTEAALEAAKKTETNKQYGFVPAENKKDSRSIEQTLADIQSKKRLKTSHGDSSSGSGNTNEPKD", "md5" : "53e9e20ef0c6f1965bf83af2360339c7", "matches" : [ { "signature" : { "accession" : "SSF82708", "name" : "R3H domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036867", "name" : "R3H_dom_sf", "description" : "R3H domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 30, "end" : 137, "hmmLength" : 124, "location-fragments" : [ { "start" : 30, "end" : 137, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.57E-20, "model-ac" : "0050562" }, { "signature" : { "accession" : "SM00393", "name" : "R3H_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001374", "name" : "R3H_dom", "description" : "R3H domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 27, "end" : 107, "hmmStart" : 1, "hmmEnd" : 83, "hmmLength" : 83, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-8, "score" : 42.6, "location-fragments" : [ { "start" : 27, "end" : 107, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-8, "score" : 42.6, "model-ac" : "SM00393" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 22, "end" : 42, "location-fragments" : [ { "start" : 22, "end" : 42, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 219, "end" : 233, "location-fragments" : [ { "start" : 219, "end" : 233, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 122, "end" : 152, "location-fragments" : [ { "start" : 122, "end" : 152, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 189, "end" : 233, "location-fragments" : [ { "start" : 189, "end" : 233, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.1370.50", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036867", "name" : "R3H_dom_sf", "description" : "R3H domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 36, "end" : 128, "hmmStart" : 8, "hmmEnd" : 92, "hmmLength" : 94, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-31, "score" : 109.8, "envelopeStart" : 36, "envelopeEnd" : 128, "postProcessed" : true, "location-fragments" : [ { "start" : 36, "end" : 128, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-31, "score" : 110.6, "model-ac" : "2cpmA00" }, { "signature" : { "accession" : "PS51061", "name" : "R3H", "description" : "R3H domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001374", "name" : "R3H_dom", "description" : "R3H domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 107, "score" : 13.585, "alignment" : "QSFRDSIQKKIHDFAKDDSQQRLKFP-PMDQIYRAVIHEIAEDANLSGCSFGEEGIDRYIMVYKK", "location-fragments" : [ { "start" : 44, "end" : 107, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51061" }, { "signature" : { "accession" : "PF01424", "name" : "R3H", "description" : "R3H domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001374", "name" : "R3H_dom", "description" : "R3H domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 106, "hmmStart" : 2, "hmmEnd" : 60, "hmmLength" : 60, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.4E-12, "score" : 46.1, "envelopeStart" : 45, "envelopeEnd" : 106, "postProcessed" : true, "location-fragments" : [ { "start" : 46, "end" : 106, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-12, "score" : 47.5, "model-ac" : "PF01424" }, { "signature" : { "accession" : "PIRSF037943", "name" : "SPAG7", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR017330", "name" : "SPAG7", "description" : "Sperm-associated antigen 7", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 231, "hmmStart" : 1, "hmmEnd" : 221, "hmmLength" : 238, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.1E-85, "score" : 280.7, "envelopeStart" : 1, "envelopeEnd" : 231, "postProcessed" : false, "location-fragments" : [ { "start" : 1, "end" : 231, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-85, "score" : 280.9, "model-ac" : "PIRSF037943" }, { "signature" : { "accession" : "PTHR13498", "name" : "SPERM ASSOCIATED ANTIGEN 7", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR017330", "name" : "SPAG7", "description" : "Sperm-associated antigen 7", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 222, "hmmStart" : 2, "hmmEnd" : 224, "hmmLength" : 227, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 225, "location-fragments" : [ { "start" : 1, "end" : 222, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-85, "familyName" : "SPERM ASSOCIATED ANTIGEN 7", "score" : 288.2, "model-ac" : "PTHR13498" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 195, "end" : 218, "location-fragments" : [ { "start" : 195, "end" : 218, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910468.1 PREDICTED: sperm-associated antigen 7 homolog [Bemisia tabaci]", "id" : "XP_018910468.1" } ] },{ "sequence" : "MELLEFSNSWLLNLCRRNGFRISNFLVLICLCHLIEYSESSTSLTFNDILPEDPKLYDKMRPPKKDGNPTIVFFHVTVMGLDSIDESSMTYAADIFFAQSWKDNRLRLPENMTSEYRLLEVDWLKNMWRPDSFFKNAKAVTFQTMTIPNHYVWLYKDKTILYMVKLTLTLSCAMNFMIYPHDTQECKLQMESLSHTTDDMVFQWDPEVPLVVGEDIELPQLQLVKNRTADCTQVYSTGNFTCLEVVFELKRRLGYYLFHTYIPTCLIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQASLPPVSYLKAVDAFMSTCTVFVFMALMEYCLVNIVLGDSDLPPKPQPEPAKPDKLFELAAKENARLLTGQPTPQQRPNPAAALAQKQRTRAINIDRFSRVFFPLLFTILNCTYWFMFAEFL", "md5" : "72d06e1beb8d6bd4c922a68758ea8c63", "matches" : [ { "signature" : { "accession" : "cd18992", "name" : "LGIC_ECD_HisCl", "description" : "LGIC_ECD_HisCl", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 69, "end" : 252, "sites" : [ { "description" : "pentamer interface", "numLocations" : 33, "siteLocations" : [ { "start" : 83, "end" : 83, "residue" : "S" }, { "start" : 149, "end" : 149, "residue" : "N" }, { "start" : 131, "end" : 131, "residue" : "D" }, { "start" : 135, "end" : 135, "residue" : "K" }, { "start" : 140, "end" : 140, "residue" : "V" }, { "start" : 219, "end" : 219, "residue" : "P" }, { "start" : 80, "end" : 80, "residue" : "G" }, { "start" : 138, "end" : 138, "residue" : "K" }, { "start" : 217, "end" : 217, "residue" : "E" }, { "start" : 166, "end" : 166, "residue" : "L" }, { "start" : 89, "end" : 89, "residue" : "M" }, { "start" : 167, "end" : 167, "residue" : "T" }, { "start" : 143, "end" : 143, "residue" : "Q" }, { "start" : 146, "end" : 146, "residue" : "T" }, { "start" : 96, "end" : 96, "residue" : "F" }, { "start" : 98, "end" : 98, "residue" : "A" }, { "start" : 153, "end" : 153, "residue" : "W" }, { "start" : 142, "end" : 142, "residue" : "F" }, { "start" : 132, "end" : 132, "residue" : "S" }, { "start" : 220, "end" : 220, "residue" : "Q" }, { "start" : 145, "end" : 145, "residue" : "M" }, { "start" : 194, "end" : 194, "residue" : "S" }, { "start" : 88, "end" : 88, "residue" : "S" }, { "start" : 119, "end" : 119, "residue" : "L" }, { "start" : 134, "end" : 134, "residue" : "F" }, { "start" : 151, "end" : 151, "residue" : "Y" }, { "start" : 137, "end" : 137, "residue" : "A" }, { "start" : 165, "end" : 165, "residue" : "K" }, { "start" : 133, "end" : 133, "residue" : "F" }, { "start" : 147, "end" : 147, "residue" : "I" }, { "start" : 252, "end" : 252, "residue" : "R" }, { "start" : 92, "end" : 92, "residue" : "A" }, { "start" : 193, "end" : 193, "residue" : "L" } ] }, { "description" : "ligand binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 153, "end" : 153, "residue" : "W" }, { "start" : 151, "end" : 151, "residue" : "Y" }, { "start" : 77, "end" : 77, "residue" : "T" }, { "start" : 96, "end" : 96, "residue" : "F" }, { "start" : 161, "end" : 161, "residue" : "L" }, { "start" : 98, "end" : 98, "residue" : "A" } ] } ], "evalue" : 6.72467E-135, "score" : 382.734, "location-fragments" : [ { "start" : 69, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18992" }, { "signature" : { "accession" : "PF02932", "name" : "Neur_chan_memb", "description" : "Neurotransmitter-gated ion-channel transmembrane region", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006029", "name" : "Neurotrans-gated_channel_TM", "description" : "Neurotransmitter-gated ion-channel transmembrane domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 260, "end" : 341, "hmmStart" : 1, "hmmEnd" : 82, "hmmLength" : 238, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.0E-23, "score" : 82.7, "envelopeStart" : 260, "envelopeEnd" : 361, "postProcessed" : true, "location-fragments" : [ { "start" : 260, "end" : 341, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-26, "score" : 93.1, "model-ac" : "PF02932" }, { "signature" : { "accession" : "cd19049", "name" : "LGIC_TM_anion", "description" : "LGIC_TM_anion", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 255, "end" : 419, "sites" : [ { "description" : "pentamer interface", "numLocations" : 35, "siteLocations" : [ { "start" : 276, "end" : 276, "residue" : "W" }, { "start" : 269, "end" : 269, "residue" : "I" }, { "start" : 283, "end" : 283, "residue" : "P" }, { "start" : 312, "end" : 312, "residue" : "Y" }, { "start" : 267, "end" : 267, "residue" : "I" }, { "start" : 404, "end" : 404, "residue" : "R" }, { "start" : 335, "end" : 335, "residue" : "C" }, { "start" : 259, "end" : 259, "residue" : "H" }, { "start" : 313, "end" : 313, "residue" : "L" }, { "start" : 328, "end" : 328, "residue" : "F" }, { "start" : 304, "end" : 304, "residue" : "Q" }, { "start" : 281, "end" : 281, "residue" : "A" }, { "start" : 270, "end" : 270, "residue" : "M" }, { "start" : 294, "end" : 294, "residue" : "L" }, { "start" : 290, "end" : 290, "residue" : "V" }, { "start" : 295, "end" : 295, "residue" : "T" }, { "start" : 301, "end" : 301, "residue" : "A" }, { "start" : 266, "end" : 266, "residue" : "L" }, { "start" : 255, "end" : 255, "residue" : "Y" }, { "start" : 273, "end" : 273, "residue" : "V" }, { "start" : 288, "end" : 288, "residue" : "L" }, { "start" : 305, "end" : 305, "residue" : "A" }, { "start" : 278, "end" : 278, "residue" : "K" }, { "start" : 287, "end" : 287, "residue" : "T" }, { "start" : 258, "end" : 258, "residue" : "F" }, { "start" : 282, "end" : 282, "residue" : "A" }, { "start" : 286, "end" : 286, "residue" : "V" }, { "start" : 291, "end" : 291, "residue" : "T" }, { "start" : 338, "end" : 338, "residue" : "N" }, { "start" : 277, "end" : 277, "residue" : "I" }, { "start" : 324, "end" : 324, "residue" : "T" }, { "start" : 302, "end" : 302, "residue" : "K" }, { "start" : 331, "end" : 331, "residue" : "L" }, { "start" : 339, "end" : 339, "residue" : "I" }, { "start" : 284, "end" : 284, "residue" : "A" } ] } ], "evalue" : 3.02082E-50, "score" : 163.777, "location-fragments" : [ { "start" : 255, "end" : 419, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd19049" }, { "signature" : { "accession" : "SSF63712", "name" : "Nicotinic receptor ligand binding domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036734", "name" : "Neur_chan_lig-bd_sf", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 56, "end" : 252, "hmmLength" : 205, "location-fragments" : [ { "start" : 56, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.45E-45, "model-ac" : "0038932" }, { "signature" : { "accession" : "SSF90112", "name" : "Neurotransmitter-gated ion-channel transmembrane pore", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036719", "name" : "Neuro-gated_channel_TM_sf", "description" : "Neurotransmitter-gated ion-channel transmembrane domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 254, "end" : 422, "hmmLength" : 250, "location-fragments" : [ { "start" : 254, "end" : 422, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.11E-42, "model-ac" : "0041811" }, { "signature" : { "accession" : "PR00253", "name" : "GABAARECEPTR", "description" : "Gamma-aminobutyric acid A (GABAA) receptor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR006028", "name" : "GABAA/Glycine_rcpt", "description" : "Gamma-aminobutyric acid A receptor/Glycine receptor alpha", "type" : "FAMILY", "goXRefs" : [ { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 256, "end" : 276, "pvalue" : 6.51E-11, "score" : 56.22, "motifNumber" : 1, "location-fragments" : [ { "start" : 256, "end" : 276, "dc-status" : "CONTINUOUS" } ] }, { "start" : 316, "end" : 337, "pvalue" : 2.21E-10, "score" : 43.81, "motifNumber" : 3, "location-fragments" : [ { "start" : 316, "end" : 337, "dc-status" : "CONTINUOUS" } ] }, { "start" : 402, "end" : 422, "pvalue" : 1.9E-8, "score" : 41.17, "motifNumber" : 4, "location-fragments" : [ { "start" : 402, "end" : 422, "dc-status" : "CONTINUOUS" } ] }, { "start" : 282, "end" : 303, "pvalue" : 2.18E-11, "score" : 46.14, "motifNumber" : 2, "location-fragments" : [ { "start" : 282, "end" : 303, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-33, "graphscan" : "IIII", "model-ac" : "PR00253" }, { "signature" : { "accession" : "G3DSA:2.70.170.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036734", "name" : "Neur_chan_lig-bd_sf", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 250, "hmmStart" : 16, "hmmEnd" : 218, "hmmLength" : 219, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.6E-62, "score" : 210.5, "envelopeStart" : 37, "envelopeEnd" : 252, "postProcessed" : true, "location-fragments" : [ { "start" : 37, "end" : 250, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-62, "score" : 210.9, "model-ac" : "5cfbA01" }, { "signature" : { "accession" : "PTHR18945:SF598", "name" : "HISTAMINE-GATED CHLORIDE CHANNEL ALPHA1 SUBUNIT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 41, "end" : 403, "hmmStart" : 5, "hmmEnd" : 356, "hmmLength" : 359, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 24, "envelopeEnd" : 407, "location-fragments" : [ { "start" : 41, "end" : 403, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-169, "familyName" : "HISTAMINE-GATED CHLORIDE CHANNEL ALPHA1 SUBUNIT", "score" : 564.3, "model-ac" : "PTHR18945:SF598" }, { "signature" : { "accession" : "PTHR18945", "name" : "NEUROTRANSMITTER GATED ION CHANNEL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 41, "end" : 403, "hmmStart" : 5, "hmmEnd" : 356, "hmmLength" : 359, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 24, "envelopeEnd" : 407, "location-fragments" : [ { "start" : 41, "end" : 403, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-169, "familyName" : "HISTAMINE-GATED CHLORIDE CHANNEL ALPHA1 SUBUNIT", "score" : 564.3, "model-ac" : "PTHR18945" }, { "signature" : { "accession" : "PF02931", "name" : "Neur_chan_LBD", "description" : "Neurotransmitter-gated ion-channel ligand binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006202", "name" : "Neur_chan_lig-bd", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 57, "end" : 252, "hmmStart" : 12, "hmmEnd" : 216, "hmmLength" : 217, "hmmBounds" : "INCOMPLETE", "evalue" : 7.5E-33, "score" : 113.8, "envelopeStart" : 45, "envelopeEnd" : 253, "postProcessed" : true, "location-fragments" : [ { "start" : 57, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-33, "score" : 114.2, "model-ac" : "PF02931" }, { "signature" : { "accession" : "PS00236", "name" : "NEUROTR_ION_CHANNEL", "description" : "Neurotransmitter-gated ion-channels signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018000", "name" : "Neurotransmitter_ion_chnl_CS", "description" : "Neurotransmitter-gated ion-channel, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 172, "end" : 186, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I1M2I2M1I1M3I1M", "alignment" : "CaMnFmiYPhDtqeC", "location-fragments" : [ { "start" : 172, "end" : 186, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00236" }, { "signature" : { "accession" : "TIGR00860", "name" : "TIGR00860", "description" : "LIC: cation transporter family protein", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 39, "end" : 341, "hmmStart" : 21, "hmmEnd" : 331, "hmmLength" : 462, "hmmBounds" : "INCOMPLETE", "evalue" : 8.2E-91, "score" : 303.0, "envelopeStart" : 14, "envelopeEnd" : 351, "postProcessed" : false, "location-fragments" : [ { "start" : 39, "end" : 341, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-95, "score" : 318.9, "model-ac" : "TIGR00860" }, { "signature" : { "accession" : "PR00252", "name" : "NRIONCHANNEL", "description" : "Neurotransmitter-gated ion channel family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 247, "end" : 259, "pvalue" : 5.42E-5, "score" : 32.96, "motifNumber" : 4, "location-fragments" : [ { "start" : 247, "end" : 259, "dc-status" : "CONTINUOUS" } ] }, { "start" : 172, "end" : 186, "pvalue" : 5.16E-5, "score" : 38.25, "motifNumber" : 3, "location-fragments" : [ { "start" : 172, "end" : 186, "dc-status" : "CONTINUOUS" } ] }, { "start" : 92, "end" : 108, "pvalue" : 2.37E-4, "score" : 33.38, "motifNumber" : 1, "location-fragments" : [ { "start" : 92, "end" : 108, "dc-status" : "CONTINUOUS" } ] }, { "start" : 126, "end" : 137, "pvalue" : 9.03E-4, "score" : 39.78, "motifNumber" : 2, "location-fragments" : [ { "start" : 126, "end" : 137, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.9E-10, "graphscan" : "IIII", "model-ac" : "PR00252" } ], "xref" : [ { "name" : "XP_018909660.1 PREDICTED: glycine receptor subunit alpha-2-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909660.1" }, { "name" : "XP_018909662.1 PREDICTED: glycine receptor subunit alpha-2-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909662.1" }, { "name" : "XP_018909661.1 PREDICTED: glycine receptor subunit alpha-2-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909661.1" } ] },{ "sequence" : "MIMDEQPHQELVKCVVVGDTAVGKTRLICARACNKQVSLSQLLNTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSLRLWDTFGDHEKDRRFAYGRSDVVLLCFSLTSHVSLRNCKAMWYPEIRRFCPQTPVLLVGCKNDLRFMYRDDSYLTYFRDKSPFVRPTRKCDLVMPDEARAVARELGIHYYETSVLTYFGVNEVFENAIRAALIARRQQRFWMTNLKKVQRPILQAPYCPPKPLLPEIFVQDSVFEDNLVELYKQQAYTDVVFVTGSVGFTAHRFILSAASPSLHRLLLLNDNAGSEVGRSASESSMVSSFGETTQGDFNEDTEHLIRTDKHSKLWKQLKRRSSCQVLSSSSSASADHCKKFNKDLSHPAFTSIKIQQCEGSDHGGHAVTSVQTIITLSKLVTSQAMQHCLQFLYTGSFDTRLPVSTLQEIRQAAEFMDLAELLVFVSNVQSHEEFLNTALKQRFKLTFRSRLNEICLGEGAFSDVLFQLDDGLFAAHRALLMARCDMMKAMFSGDFRESNAKVILFPGVKEETFEQLMTFLYTDKVSSDFLYCKKTAAVSQSRHHVLDILELANRLCLPRLVNLIEKKIVEELISLSGTNESEIVQHCIRLLEPCKLHNADQLADWLMSYLCVNYDKLCKLSPKLLRMLHPDNQLYITEQRWPPVWYLKDYDNYEKCKSEREKEDRLLFKRSSSPSGCLCFSSSSKASRTTPANHMSLTSSSDRPPPQIVVGFTLA", "md5" : "59bd069eb727d9315d9a29e056f7fbbd", "matches" : [ { "signature" : { "accession" : "cd18499", "name" : "BACK_RHOBTB", "description" : "BACK_RHOBTB", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 611, "end" : 687, "sites" : [ ], "evalue" : 1.89997E-29, "score" : 109.633, "location-fragments" : [ { "start" : 611, "end" : 687, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18499" }, { "signature" : { "accession" : "PS50097", "name" : "BTB", "description" : "BTB domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000210", "name" : "BTB/POZ_dom", "description" : "BTB/POZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 490, "end" : 557, "score" : 15.659, "alignment" : "SDVLFQLDDGLFAAHRALLMARCDMMKAMFSGDFRESNAkVILFPGVKEETFEQLMTFLYTDKVSSDF", "location-fragments" : [ { "start" : 490, "end" : 557, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50097" }, { "signature" : { "accession" : "SM00173", "name" : "ras_sub_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 211, "hmmStart" : 1, "hmmEnd" : 167, "hmmLength" : 167, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-5, "score" : -28.0, "location-fragments" : [ { "start" : 9, "end" : 211, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-5, "score" : -28.0, "model-ac" : "SM00173" }, { "signature" : { "accession" : "PS51420", "name" : "RHO", "description" : "small GTPase Rho family profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR003578", "name" : "Small_GTPase_Rho", "description" : "Small GTPase Rho", "type" : "FAMILY", "goXRefs" : [ { "name" : "small GTPase mediated signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007264" }, { "name" : "GTP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005525" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 5, "end" : 208, "score" : 18.522, "alignment" : "EQPHQELVKCVVVGDTAVGKTRLICARACNkQVsLSQLlnthVPTVWaiDqyRIYKDVLErsweVVDgvNVSLRLWDTFGD--HEKDRRFAYGRSDVVLLCFSLTSHVSLRNCKAMWYPEIRRFCPQTPVLLVGCKNDLrfmYRDDSYLTyFRDKSpfvrptrKCDLVMPDEARAVARELG-IHYYETSVLTYFGVNEVFENAIRAA", "location-fragments" : [ { "start" : 5, "end" : 208, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51420" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 216, "hmmLength" : 175, "location-fragments" : [ { "start" : 10, "end" : 216, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.03E-31, "model-ac" : "0052005" }, { "signature" : { "accession" : "G3DSA:3.30.710.10", "name" : "Potassium Channel Kv1.1; Chain A", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 477, "end" : 648, "hmmStart" : 10, "hmmEnd" : 149, "hmmLength" : 153, "hmmBounds" : "COMPLETE", "evalue" : 7.0E-32, "score" : 112.5, "envelopeStart" : 477, "envelopeEnd" : 648, "postProcessed" : true, "location-fragments" : [ { "start" : 477, "end" : 648, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-46, "score" : 159.6, "model-ac" : "3hqiA02" }, { "signature" : { "accession" : "SM00175", "name" : "rab_sub_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 211, "hmmStart" : 1, "hmmEnd" : 172, "hmmLength" : 172, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-7, "score" : -17.9, "location-fragments" : [ { "start" : 12, "end" : 211, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-7, "score" : -17.9, "model-ac" : "SM00175" }, { "signature" : { "accession" : "cd01873", "name" : "RhoBTB", "description" : "RhoBTB", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 208, "sites" : [ { "description" : "Switch I region", "numLocations" : 7, "siteLocations" : [ { "start" : 48, "end" : 48, "residue" : "P" }, { "start" : 54, "end" : 54, "residue" : "D" }, { "start" : 49, "end" : 49, "residue" : "T" }, { "start" : 53, "end" : 53, "residue" : "I" }, { "start" : 50, "end" : 50, "residue" : "V" }, { "start" : 52, "end" : 52, "residue" : "A" }, { "start" : 51, "end" : 51, "residue" : "W" } ] }, { "description" : "putative GDI (guanine nucleotide dissociation inhibitor) interaction", "numLocations" : 4, "siteLocations" : [ { "start" : 91, "end" : 91, "residue" : "R" }, { "start" : 50, "end" : 50, "residue" : "V" }, { "start" : 83, "end" : 83, "residue" : "F" }, { "start" : 93, "end" : 93, "residue" : "A" } ] }, { "description" : "putative GEF (guanine nucleotide exchange factor) interaction site", "numLocations" : 15, "siteLocations" : [ { "start" : 91, "end" : 91, "residue" : "R" }, { "start" : 49, "end" : 49, "residue" : "T" }, { "start" : 13, "end" : 13, "residue" : "K" }, { "start" : 55, "end" : 55, "residue" : "Q" }, { "start" : 83, "end" : 83, "residue" : "F" }, { "start" : 94, "end" : 94, "residue" : "Y" }, { "start" : 54, "end" : 54, "residue" : "D" }, { "start" : 84, "end" : 84, "residue" : "G" }, { "start" : 76, "end" : 76, "residue" : "S" }, { "start" : 81, "end" : 81, "residue" : "D" }, { "start" : 57, "end" : 57, "residue" : "R" }, { "start" : 50, "end" : 50, "residue" : "V" }, { "start" : 59, "end" : 59, "residue" : "Y" }, { "start" : 80, "end" : 80, "residue" : "W" }, { "start" : 85, "end" : 85, "residue" : "D" } ] }, { "description" : "G3 box", "numLocations" : 4, "siteLocations" : [ { "start" : 84, "end" : 84, "residue" : "G" }, { "start" : 81, "end" : 81, "residue" : "D" }, { "start" : 82, "end" : 82, "residue" : "T" }, { "start" : 83, "end" : 83, "residue" : "F" } ] }, { "description" : "putative GAP (GTPase-activating protein) interaction site", "numLocations" : 4, "siteLocations" : [ { "start" : 91, "end" : 91, "residue" : "R" }, { "start" : 50, "end" : 50, "residue" : "V" }, { "start" : 51, "end" : 51, "residue" : "W" }, { "start" : 85, "end" : 85, "residue" : "D" } ] }, { "description" : "G5 box", "numLocations" : 3, "siteLocations" : [ { "start" : 190, "end" : 190, "residue" : "S" }, { "start" : 192, "end" : 192, "residue" : "L" }, { "start" : 191, "end" : 191, "residue" : "V" } ] }, { "description" : "G1 box", "numLocations" : 8, "siteLocations" : [ { "start" : 22, "end" : 22, "residue" : "V" }, { "start" : 19, "end" : 19, "residue" : "D" }, { "start" : 18, "end" : 18, "residue" : "G" }, { "start" : 24, "end" : 24, "residue" : "K" }, { "start" : 25, "end" : 25, "residue" : "T" }, { "start" : 20, "end" : 20, "residue" : "T" }, { "start" : 23, "end" : 23, "residue" : "G" }, { "start" : 21, "end" : 21, "residue" : "A" } ] }, { "description" : "G2 box", "numLocations" : 1, "siteLocations" : [ { "start" : 49, "end" : 49, "residue" : "T" } ] }, { "description" : "putative effector interaction site", "numLocations" : 4, "siteLocations" : [ { "start" : 91, "end" : 91, "residue" : "R" }, { "start" : 52, "end" : 52, "residue" : "A" }, { "start" : 51, "end" : 51, "residue" : "W" }, { "start" : 94, "end" : 94, "residue" : "Y" } ] }, { "description" : "Switch II region", "numLocations" : 9, "siteLocations" : [ { "start" : 84, "end" : 84, "residue" : "G" }, { "start" : 91, "end" : 91, "residue" : "R" }, { "start" : 97, "end" : 97, "residue" : "S" }, { "start" : 92, "end" : 92, "residue" : "F" }, { "start" : 98, "end" : 98, "residue" : "D" }, { "start" : 94, "end" : 94, "residue" : "Y" }, { "start" : 93, "end" : 93, "residue" : "A" }, { "start" : 85, "end" : 85, "residue" : "D" }, { "start" : 99, "end" : 99, "residue" : "V" } ] }, { "description" : "G4 box", "numLocations" : 4, "siteLocations" : [ { "start" : 138, "end" : 138, "residue" : "K" }, { "start" : 139, "end" : 139, "residue" : "N" }, { "start" : 140, "end" : 140, "residue" : "D" }, { "start" : 137, "end" : 137, "residue" : "C" } ] }, { "description" : "GTP/Mg2+ binding site", "numLocations" : 13, "siteLocations" : [ { "start" : 22, "end" : 22, "residue" : "V" }, { "start" : 192, "end" : 192, "residue" : "L" }, { "start" : 24, "end" : 24, "residue" : "K" }, { "start" : 23, "end" : 23, "residue" : "G" }, { "start" : 21, "end" : 21, "residue" : "A" }, { "start" : 26, "end" : 26, "residue" : "R" }, { "start" : 84, "end" : 84, "residue" : "G" }, { "start" : 138, "end" : 138, "residue" : "K" }, { "start" : 140, "end" : 140, "residue" : "D" }, { "start" : 25, "end" : 25, "residue" : "T" }, { "start" : 81, "end" : 81, "residue" : "D" }, { "start" : 191, "end" : 191, "residue" : "V" }, { "start" : 82, "end" : 82, "residue" : "T" } ] } ], "evalue" : 3.70758E-116, "score" : 346.185, "location-fragments" : [ { "start" : 10, "end" : 208, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01873" }, { "signature" : { "accession" : "SSF54695", "name" : "POZ domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011333", "name" : "SKP1/BTB/POZ_sf", "description" : "SKP1/BTB/POZ domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 483, "end" : 598, "hmmLength" : 122, "location-fragments" : [ { "start" : 483, "end" : 598, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.26E-22, "model-ac" : "0043098" }, { "signature" : { "accession" : "PR00449", "name" : "RASTRNSFRMNG", "description" : "Transforming protein P21 ras signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : null }, "locations" : [ { "start" : 128, "end" : 141, "pvalue" : 4.79E-5, "score" : 44.94, "motifNumber" : 4, "location-fragments" : [ { "start" : 128, "end" : 141, "dc-status" : "CONTINUOUS" } ] }, { "start" : 68, "end" : 90, "pvalue" : 4.33E-5, "score" : 31.27, "motifNumber" : 3, "location-fragments" : [ { "start" : 68, "end" : 90, "dc-status" : "CONTINUOUS" } ] }, { "start" : 12, "end" : 33, "pvalue" : 1.46E-7, "score" : 39.01, "motifNumber" : 1, "location-fragments" : [ { "start" : 12, "end" : 33, "dc-status" : "CONTINUOUS" } ] }, { "start" : 186, "end" : 208, "pvalue" : 2.59E-6, "score" : 31.75, "motifNumber" : 5, "location-fragments" : [ { "start" : 186, "end" : 208, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.1E-16, "graphscan" : "I.III", "model-ac" : "PR00449" }, { "signature" : { "accession" : "PTHR24072", "name" : "RHO FAMILY GTPASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 543, "hmmStart" : 2, "hmmEnd" : 521, "hmmLength" : 677, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 732, "location-fragments" : [ { "start" : 3, "end" : 543, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-215, "familyName" : "RHO-RELATED BTB DOMAIN CONTAINING, ISOFORM B", "score" : 720.6, "model-ac" : "PTHR24072" }, { "signature" : { "accession" : "SM00174", "name" : "rho_sub_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 211, "hmmStart" : 1, "hmmEnd" : 180, "hmmLength" : 180, "hmmBounds" : "COMPLETE", "evalue" : 6.2E-27, "score" : 105.5, "location-fragments" : [ { "start" : 14, "end" : 211, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.2E-27, "score" : 105.5, "model-ac" : "SM00174" }, { "signature" : { "accession" : "PF00651", "name" : "BTB", "description" : "BTB/POZ domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000210", "name" : "BTB/POZ_dom", "description" : "BTB/POZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 257, "end" : 298, "hmmStart" : 3, "hmmEnd" : 45, "hmmLength" : 111, "hmmBounds" : "INCOMPLETE", "evalue" : 6.8E-6, "score" : 26.3, "envelopeStart" : 255, "envelopeEnd" : 317, "postProcessed" : true, "location-fragments" : [ { "start" : 257, "end" : 298, "dc-status" : "CONTINUOUS" } ] }, { "start" : 486, "end" : 598, "hmmStart" : 7, "hmmEnd" : 109, "hmmLength" : 111, "hmmBounds" : "INCOMPLETE", "evalue" : 5.7E-18, "score" : 65.2, "envelopeStart" : 480, "envelopeEnd" : 600, "postProcessed" : true, "location-fragments" : [ { "start" : 486, "end" : 598, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-30, "score" : 104.5, "model-ac" : "PF00651" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 213, "hmmStart" : 4, "hmmEnd" : 167, "hmmLength" : 171, "hmmBounds" : "COMPLETE", "evalue" : 7.7E-48, "score" : 164.2, "envelopeStart" : 8, "envelopeEnd" : 213, "postProcessed" : true, "location-fragments" : [ { "start" : 8, "end" : 213, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.7E-48, "score" : 165.2, "model-ac" : "1ryhA00" }, { "signature" : { "accession" : "PS50097", "name" : "BTB", "description" : "BTB domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000210", "name" : "BTB/POZ_dom", "description" : "BTB/POZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 265, "end" : 294, "score" : 8.876, "alignment" : "TDVVFVTGSVGFTAHRFILSAASPSLHRLL-------------------------------------", "location-fragments" : [ { "start" : 265, "end" : 294, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50097" }, { "signature" : { "accession" : "SM00225", "name" : "BTB_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000210", "name" : "BTB/POZ_dom", "description" : "BTB/POZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 265, "end" : 461, "hmmStart" : 1, "hmmEnd" : 114, "hmmLength" : 114, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-5, "score" : 34.1, "location-fragments" : [ { "start" : 265, "end" : 461, "dc-status" : "CONTINUOUS" } ] }, { "start" : 490, "end" : 600, "hmmStart" : 1, "hmmEnd" : 114, "hmmLength" : 114, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-13, "score" : 61.2, "location-fragments" : [ { "start" : 490, "end" : 600, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.1E-24, "score" : 95.3, "model-ac" : "SM00225" }, { "signature" : { "accession" : "SSF54695", "name" : "POZ domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011333", "name" : "SKP1/BTB/POZ_sf", "description" : "SKP1/BTB/POZ domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 251, "end" : 452, "hmmLength" : 122, "location-fragments" : [ { "start" : 392, "end" : 452, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 251, "end" : 295, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.18E-14, "model-ac" : "0043098" }, { "signature" : { "accession" : "cd18299", "name" : "BTB1_POZ_RhoBTB", "description" : "BTB1_POZ_RhoBTB", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 253, "end" : 458, "sites" : [ ], "evalue" : 5.73368E-13, "score" : 63.3843, "location-fragments" : [ { "start" : 253, "end" : 458, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18299" }, { "signature" : { "accession" : "PF00071", "name" : "Ras", "description" : "Ras family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001806", "name" : "Small_GTPase", "description" : "Small GTPase", "type" : "FAMILY", "goXRefs" : [ { "name" : "GTPase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003924" }, { "name" : "GTP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005525" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 208, "hmmStart" : 1, "hmmEnd" : 160, "hmmLength" : 162, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.3E-23, "score" : 83.3, "envelopeStart" : 13, "envelopeEnd" : 210, "postProcessed" : true, "location-fragments" : [ { "start" : 13, "end" : 208, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-24, "score" : 85.8, "model-ac" : "PF00071" }, { "signature" : { "accession" : "cd18300", "name" : "BTB2_POZ_RhoBTB", "description" : "BTB2_POZ_RhoBTB", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 481, "end" : 600, "sites" : [ ], "evalue" : 2.5417E-41, "score" : 144.304, "location-fragments" : [ { "start" : 481, "end" : 600, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18300" }, { "signature" : { "accession" : "PTHR24072:SF156", "name" : "RHO-RELATED BTB DOMAIN CONTAINING, ISOFORM B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 543, "hmmStart" : 2, "hmmEnd" : 521, "hmmLength" : 677, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 732, "location-fragments" : [ { "start" : 3, "end" : 543, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-215, "familyName" : "RHO-RELATED BTB DOMAIN CONTAINING, ISOFORM B", "score" : 720.6, "model-ac" : "PTHR24072:SF156" } ], "xref" : [ { "name" : "XP_018910262.1 PREDICTED: rho-related BTB domain-containing protein 1 [Bemisia tabaci]", "id" : "XP_018910262.1" }, { "name" : "XP_018910265.1 PREDICTED: rho-related BTB domain-containing protein 1 [Bemisia tabaci]", "id" : "XP_018910265.1" }, { "name" : "XP_018910264.1 PREDICTED: rho-related BTB domain-containing protein 1 [Bemisia tabaci]", "id" : "XP_018910264.1" }, { "name" : "XP_018910263.1 PREDICTED: rho-related BTB domain-containing protein 1 [Bemisia tabaci]", "id" : "XP_018910263.1" } ] },{ "sequence" : "MDFSFCPNFSPDLELSVFHLIWFSRNSITNSLSIYVKSNTGNTVSVDLDPKWDIKNVKEVVAPRLGLEPEEVKIIFAGKELPDSVLLEECDLGQQSILHAVKSRKKLVSESKPLCETLLDFSLSEISERAEEEETTLDDDEKIIPEKAHFYVYCASPCKGMRTGKLRVRCANCKSGAITVDRDPQSWADVLESERISGHCEEETCSSGPISWVEFYFKCAEHTSQGEMDQAVPLYLIRPNSQHVPCLACGDVSDPVLVFSCSVGHVTCLECFNLYCVSRLRERQFTMDETHGYTLPCPAGCEDSLIKEIHHFHLLNDEHYAMYQRFGMEEYVLKNGGVLCPQPGCGAGILVEPDCTRITCAGGCGYVFCRNCLQGYHIGECETVEEIEKTGTSSYAVNPECVSQARWDEASKVAIKVTTKPCPKCRTATERDGGCMHMLCTRCAFQWCWVCQIEWNRDCMGRHWFG", "md5" : "05c61d3cd88cae75f64adb317d83bea1", "matches" : [ { "signature" : { "accession" : "PR01475", "name" : "PARKIN", "description" : "Parkin signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR003977", "name" : "Parkin", "description" : "E3 ubiquitin-protein ligase parkin", "type" : "FAMILY", "goXRefs" : [ { "name" : "cytosol", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005829" }, { "name" : "ubiquitin-protein transferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004842" }, { "name" : "mitochondrion", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005739" } ], "pathwayXRefs" : [ { "name" : "Aggrephagy", "databaseName" : "Reactome", "id" : "R-HSA-9646399" }, { "name" : "Pink/Parkin Mediated Mitophagy", "databaseName" : "Reactome", "id" : "R-HSA-5205685" }, { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" }, { "name" : "Josephin domain DUBs", "databaseName" : "Reactome", "id" : "R-HSA-5689877" }, { "name" : "Amyloid fiber formation", "databaseName" : "Reactome", "id" : "R-HSA-977225" } ] } }, "locations" : [ { "start" : 229, "end" : 249, "pvalue" : 1.54E-8, "score" : 48.41, "motifNumber" : 5, "location-fragments" : [ { "start" : 229, "end" : 249, "dc-status" : "CONTINUOUS" } ] }, { "start" : 61, "end" : 81, "pvalue" : 1.95E-10, "score" : 52.38, "motifNumber" : 1, "location-fragments" : [ { "start" : 61, "end" : 81, "dc-status" : "CONTINUOUS" } ] }, { "start" : 179, "end" : 202, "pvalue" : 9.85E-9, "score" : 47.92, "motifNumber" : 3, "location-fragments" : [ { "start" : 179, "end" : 202, "dc-status" : "CONTINUOUS" } ] }, { "start" : 212, "end" : 222, "pvalue" : 5.54E-5, "score" : 56.06, "motifNumber" : 4, "location-fragments" : [ { "start" : 212, "end" : 222, "dc-status" : "CONTINUOUS" } ] }, { "start" : 308, "end" : 329, "pvalue" : 2.98E-9, "score" : 50.76, "motifNumber" : 7, "location-fragments" : [ { "start" : 308, "end" : 329, "dc-status" : "CONTINUOUS" } ] }, { "start" : 443, "end" : 465, "pvalue" : 4.47E-12, "score" : 63.77, "motifNumber" : 9, "location-fragments" : [ { "start" : 443, "end" : 465, "dc-status" : "CONTINUOUS" } ] }, { "start" : 337, "end" : 353, "pvalue" : 1.7E-11, "score" : 74.51, "motifNumber" : 8, "location-fragments" : [ { "start" : 337, "end" : 353, "dc-status" : "CONTINUOUS" } ] }, { "start" : 158, "end" : 173, "pvalue" : 1.04E-6, "score" : 52.08, "motifNumber" : 2, "location-fragments" : [ { "start" : 158, "end" : 173, "dc-status" : "CONTINUOUS" } ] }, { "start" : 257, "end" : 273, "pvalue" : 8.66E-8, "score" : 54.9, "motifNumber" : 6, "location-fragments" : [ { "start" : 257, "end" : 273, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-68, "graphscan" : "IIIIIIIII", "model-ac" : "PR01475" }, { "signature" : { "accession" : "SSF54236", "name" : "Ubiquitin-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029071", "name" : "Ubiquitin-like_domsf", "description" : "Ubiquitin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 28, "end" : 105, "hmmLength" : 94, "location-fragments" : [ { "start" : 28, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.53E-15, "model-ac" : "0050735" }, { "signature" : { "accession" : "G3DSA:3.10.20.90", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 29, "end" : 106, "hmmStart" : 6, "hmmEnd" : 76, "hmmLength" : 81, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-15, "score" : 58.8, "envelopeStart" : 29, "envelopeEnd" : 106, "postProcessed" : true, "location-fragments" : [ { "start" : 29, "end" : 106, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-16, "score" : 59.8, "model-ac" : "4zynB01" }, { "signature" : { "accession" : "SSF57850", "name" : "RING/U-box", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 329, "end" : 384, "hmmLength" : 73, "location-fragments" : [ { "start" : 329, "end" : 384, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.51E-8, "model-ac" : "0052291" }, { "signature" : { "accession" : "PF01485", "name" : "IBR", "description" : "IBR domain, a half RING-finger domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002867", "name" : "IBR_dom", "description" : "IBR domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 416, "end" : 459, "hmmStart" : 15, "hmmEnd" : 60, "hmmLength" : 62, "hmmBounds" : "INCOMPLETE", "evalue" : 1.4E-6, "score" : 28.4, "envelopeStart" : 403, "envelopeEnd" : 461, "postProcessed" : true, "location-fragments" : [ { "start" : 416, "end" : 459, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-14, "score" : 52.5, "model-ac" : "PF01485" }, { "signature" : { "accession" : "SM00647", "name" : "ibrneu5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002867", "name" : "IBR_dom", "description" : "IBR domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 405, "end" : 459, "hmmStart" : 1, "hmmEnd" : 78, "hmmLength" : 78, "hmmBounds" : "COMPLETE", "evalue" : 0.3, "score" : 7.6, "location-fragments" : [ { "start" : 405, "end" : 459, "dc-status" : "CONTINUOUS" } ] }, { "start" : 321, "end" : 381, "hmmStart" : 1, "hmmEnd" : 78, "hmmLength" : 78, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-16, "score" : 70.3, "location-fragments" : [ { "start" : 321, "end" : 381, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-18, "score" : 77.9, "model-ac" : "SM00647" }, { "signature" : { "accession" : "cd01798", "name" : "Ubl_parkin", "description" : "Ubl_parkin", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 34, "end" : 106, "sites" : [ { "description" : "key conserved lysines", "numLocations" : 3, "siteLocations" : [ { "start" : 58, "end" : 58, "residue" : "K" }, { "start" : 79, "end" : 79, "residue" : "K" }, { "start" : 37, "end" : 37, "residue" : "K" } ] }, { "description" : "Arg42Pro mutation site", "numLocations" : 1, "siteLocations" : [ { "start" : 73, "end" : 73, "residue" : "K" } ] }, { "description" : "key conserved lysine K27", "numLocations" : 1, "siteLocations" : [ { "start" : 58, "end" : 58, "residue" : "K" } ] }, { "description" : "Ring1 interaction site", "numLocations" : 13, "siteLocations" : [ { "start" : 42, "end" : 42, "residue" : "N" }, { "start" : 103, "end" : 103, "residue" : "S" }, { "start" : 75, "end" : 75, "residue" : "I" }, { "start" : 101, "end" : 101, "residue" : "V" }, { "start" : 45, "end" : 45, "residue" : "S" }, { "start" : 99, "end" : 99, "residue" : "H" }, { "start" : 41, "end" : 41, "residue" : "G" }, { "start" : 76, "end" : 76, "residue" : "F" }, { "start" : 37, "end" : 37, "residue" : "K" }, { "start" : 39, "end" : 39, "residue" : "N" }, { "start" : 77, "end" : 77, "residue" : "A" }, { "start" : 78, "end" : 78, "residue" : "G" }, { "start" : 40, "end" : 40, "residue" : "T" } ] }, { "description" : "SH3 interaction site", "numLocations" : 13, "siteLocations" : [ { "start" : 103, "end" : 103, "residue" : "S" }, { "start" : 75, "end" : 75, "residue" : "I" }, { "start" : 102, "end" : 102, "residue" : "K" }, { "start" : 101, "end" : 101, "residue" : "V" }, { "start" : 99, "end" : 99, "residue" : "H" }, { "start" : 80, "end" : 80, "residue" : "E" }, { "start" : 104, "end" : 104, "residue" : "R" }, { "start" : 106, "end" : 106, "residue" : "K" }, { "start" : 37, "end" : 37, "residue" : "K" }, { "start" : 39, "end" : 39, "residue" : "N" }, { "start" : 78, "end" : 78, "residue" : "G" }, { "start" : 73, "end" : 73, "residue" : "K" }, { "start" : 105, "end" : 105, "residue" : "K" } ] } ], "evalue" : 4.83231E-33, "score" : 117.783, "location-fragments" : [ { "start" : 34, "end" : 106, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01798" }, { "signature" : { "accession" : "PS50053", "name" : "UBIQUITIN_2", "description" : "Ubiquitin domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000626", "name" : "Ubiquitin-like_dom", "description" : "Ubiquitin-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 101, "score" : 16.407, "alignment" : "LSIYVKSNTGNTVSVDLDPKWDIKNVKEVVAPRLGLEPEEVKIIFAGKELPDSVLLEECDLGQQSILHAV------", "location-fragments" : [ { "start" : 32, "end" : 101, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50053" }, { "signature" : { "accession" : "cd16627", "name" : "RING-HC_RBR_parkin", "description" : "RING-HC_RBR_parkin", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 244, "end" : 302, "sites" : [ { "description" : "Zn binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 246, "end" : 246, "residue" : "C" }, { "start" : 265, "end" : 265, "residue" : "H" }, { "start" : 268, "end" : 268, "residue" : "C" }, { "start" : 249, "end" : 249, "residue" : "C" }, { "start" : 297, "end" : 297, "residue" : "C" }, { "start" : 271, "end" : 271, "residue" : "C" }, { "start" : 261, "end" : 261, "residue" : "C" }, { "start" : 301, "end" : 301, "residue" : "C" } ] }, { "description" : "polypeptide substrate binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 292, "end" : 292, "residue" : "G" }, { "start" : 293, "end" : 293, "residue" : "Y" }, { "start" : 291, "end" : 291, "residue" : "H" } ] } ], "evalue" : 3.82853E-25, "score" : 95.8129, "location-fragments" : [ { "start" : 244, "end" : 302, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd16627" }, { "signature" : { "accession" : "PTHR11685", "name" : "RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR031127", "name" : "E3_UB_ligase_RBR", "description" : "E3 ubiquitin ligase RBR family", "type" : "FAMILY", "goXRefs" : [ { "name" : "protein ubiquitination", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0016567" }, { "name" : "ubiquitin-protein transferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004842" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 460, "hmmStart" : 1, "hmmEnd" : 455, "hmmLength" : 461, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 32, "envelopeEnd" : 465, "location-fragments" : [ { "start" : 32, "end" : 460, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-174, "familyName" : "E3 UBIQUITIN-PROTEIN LIGASE PARKIN", "score" : 584.1, "model-ac" : "PTHR11685" }, { "signature" : { "accession" : "G3DSA:1.20.120.1750", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 384, "end" : 465, "hmmStart" : 14, "hmmEnd" : 69, "hmmLength" : 239, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.2E-14, "score" : 54.1, "envelopeStart" : 379, "envelopeEnd" : 465, "postProcessed" : true, "location-fragments" : [ { "start" : 384, "end" : 465, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-16, "score" : 62.8, "model-ac" : "4kblB02" }, { "signature" : { "accession" : "G3DSA:2.20.25.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 338, "end" : 383, "hmmStart" : 1, "hmmEnd" : 52, "hmmLength" : 55, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.6E-21, "score" : 78.0, "envelopeStart" : 338, "envelopeEnd" : 388, "postProcessed" : true, "location-fragments" : [ { "start" : 338, "end" : 383, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-21, "score" : 78.0, "model-ac" : "2jmoA01" }, { "signature" : { "accession" : "PTHR11685:SF214", "name" : "E3 UBIQUITIN-PROTEIN LIGASE PARKIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 32, "end" : 460, "hmmStart" : 1, "hmmEnd" : 455, "hmmLength" : 461, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 32, "envelopeEnd" : 465, "location-fragments" : [ { "start" : 32, "end" : 460, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-174, "familyName" : "E3 UBIQUITIN-PROTEIN LIGASE PARKIN", "score" : 584.1, "model-ac" : "PTHR11685:SF214" }, { "signature" : { "accession" : "PF00240", "name" : "ubiquitin", "description" : "Ubiquitin family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000626", "name" : "Ubiquitin-like_dom", "description" : "Ubiquitin-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 34, "end" : 103, "hmmStart" : 1, "hmmEnd" : 70, "hmmLength" : 72, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.9E-15, "score" : 55.4, "envelopeStart" : 34, "envelopeEnd" : 105, "postProcessed" : true, "location-fragments" : [ { "start" : 34, "end" : 103, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-15, "score" : 56.2, "model-ac" : "PF00240" }, { "signature" : { "accession" : "SSF57850", "name" : "RING/U-box", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 410, "end" : 457, "hmmLength" : 73, "location-fragments" : [ { "start" : 410, "end" : 457, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-12, "model-ac" : "0052291" }, { "signature" : { "accession" : "PF17976", "name" : "zf-RING_12", "description" : "RING/Ubox like zinc-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR041565", "name" : "Parkin_Znf-RING", "description" : "Parkin, RING/Ubox like zinc-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Pink/Parkin Mediated Mitophagy", "databaseName" : "Reactome", "id" : "R-HSA-5205685" }, { "name" : "Amyloid fiber formation", "databaseName" : "Reactome", "id" : "R-HSA-977225" }, { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" }, { "name" : "Aggrephagy", "databaseName" : "Reactome", "id" : "R-HSA-9646399" }, { "name" : "Josephin domain DUBs", "databaseName" : "Reactome", "id" : "R-HSA-5689877" } ] } }, "locations" : [ { "start" : 149, "end" : 224, "hmmStart" : 1, "hmmEnd" : 73, "hmmLength" : 73, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-31, "score" : 108.3, "envelopeStart" : 149, "envelopeEnd" : 224, "postProcessed" : true, "location-fragments" : [ { "start" : 149, "end" : 224, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-31, "score" : 108.3, "model-ac" : "PF17976" }, { "signature" : { "accession" : "PS51873", "name" : "TRIAD", "description" : "TRIAD supradomain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 242, "end" : 466, "score" : 34.055, "alignment" : "QHVPCLACGDV---SDPVLVFSCSvgHVTCLECFNLYCVSRlrerqfTMDETHGYTLPCPA-GCeDSLIKEIHHFHLLNDEHYAMYQRFGMEEYVLKNG--GvLCPQPGCGAGILV--EPDCTRITCAgGCGYVFCRNCLQGYHIG-ECEtveEIEKTgtssYAVNPECVSQARWDEaskvaikVTTKPCPKCRTATERDGGCMHMLCTRCAFQWCWVCQIEWNRDCMGRhWFG-----", "location-fragments" : [ { "start" : 242, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51873" }, { "signature" : { "accession" : "PIRSF037880", "name" : "Parkin", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR003977", "name" : "Parkin", "description" : "E3 ubiquitin-protein ligase parkin", "type" : "FAMILY", "goXRefs" : [ { "name" : "cytosol", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005829" }, { "name" : "ubiquitin-protein transferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004842" }, { "name" : "mitochondrion", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005739" } ], "pathwayXRefs" : [ { "name" : "Aggrephagy", "databaseName" : "Reactome", "id" : "R-HSA-9646399" }, { "name" : "Pink/Parkin Mediated Mitophagy", "databaseName" : "Reactome", "id" : "R-HSA-5205685" }, { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" }, { "name" : "Josephin domain DUBs", "databaseName" : "Reactome", "id" : "R-HSA-5689877" }, { "name" : "Amyloid fiber formation", "databaseName" : "Reactome", "id" : "R-HSA-977225" } ] } }, "locations" : [ { "start" : 25, "end" : 466, "hmmStart" : 28, "hmmEnd" : 466, "hmmLength" : 456, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.1E-179, "score" : 593.8, "envelopeStart" : 25, "envelopeEnd" : 466, "postProcessed" : false, "location-fragments" : [ { "start" : 25, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-180, "score" : 595.0, "model-ac" : "PIRSF037880" }, { "signature" : { "accession" : "PF17978", "name" : "zf-RING_14", "description" : "RING/Ubox like zinc-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR041170", "name" : "Znf-RING_14", "description" : "RING/Ubox-like zinc-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Aggrephagy", "databaseName" : "Reactome", "id" : "R-HSA-9646399" }, { "name" : "Amyloid fiber formation", "databaseName" : "Reactome", "id" : "R-HSA-977225" }, { "name" : "Josephin domain DUBs", "databaseName" : "Reactome", "id" : "R-HSA-5689877" }, { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" }, { "name" : "Pink/Parkin Mediated Mitophagy", "databaseName" : "Reactome", "id" : "R-HSA-5205685" } ] } }, "locations" : [ { "start" : 236, "end" : 326, "hmmStart" : 1, "hmmEnd" : 91, "hmmLength" : 91, "hmmBounds" : "COMPLETE", "evalue" : 2.6E-42, "score" : 143.2, "envelopeStart" : 236, "envelopeEnd" : 326, "postProcessed" : true, "location-fragments" : [ { "start" : 236, "end" : 326, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-42, "score" : 143.2, "model-ac" : "PF17978" }, { "signature" : { "accession" : "SM00213", "name" : "ubq_7", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000626", "name" : "Ubiquitin-like_dom", "description" : "Ubiquitin-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 103, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 72, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-13, "score" : 60.4, "location-fragments" : [ { "start" : 32, "end" : 103, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-13, "score" : 60.4, "model-ac" : "SM00213" } ], "xref" : [ { "name" : "XP_018909608.1 PREDICTED: E3 ubiquitin-protein ligase parkin [Bemisia tabaci]", "id" : "XP_018909608.1" } ] },{ "sequence" : "MEVAQRSWRLVEFTAHTAPVNCLALGHKSGRVLVTGGDDKKVNLWAVGKENCIMSLSGHGTPIETVRFSSSEDMVCAGSRDGVLKVWDLEAAKIVRTLIGHQDCMKSVDFHPYAEFLASGSVDSTIKLWDIRKKGCIFTYRGHIGSVNSVKFSPDGQWIASGGEDSTVKIWDLRTGSVLHDFIKHDGPVLSVEYHPHEFLLASSSTDKTVHFWDLDKFTSISATEKQAHASRCIRFSEGGECLFAGACDTLNVFGWEPLRSLDTVFTQWSKIRDISTVGSQLIGAGYQAEGVMIYVVDLAKVCPIGKPLPPASPFAHGMSIRKSFNKQKPAPKSTAVKHQKPIEENETEPEDENLADIPDVNNYEAVFCPNRTLNRSPPPNEELFTPPGNITELNAPAQTSLHSGSQLAAETEEEYYEETEPSPKDHAPKSIYVSKNKQSSSSEVMSPVSSSICHTVSTLTSGMTHTAPGQNHSSMPASLNSLSPTSSSDHSFSRLGSANHADSSKEARSQSYDDPSKILARAINFYPKIRTSEYRILCRKTIGKIKNMPGPLKATTKRFIASLKTHRVCNFESSPSEPAISNSARKVGNGIGVKVSNNHKPELPPKPKYQLSVKQHQNNAKNIMMKPGKRPGAGEDDNIEYIPMTGDTPVGLEPNEFLPKRGSGGQLSEAEVISSVMRGHEDMMRVLISRQRNLQIIFSVWHTKDLKSAVEMATDMNDLSVVVDLLSALTRKPNLWSLDLCNLLLPSIRELLQSKYETYVTVGCDALRLILRNFSSVIRNNVQWSCPTIGVDITKEERYNKCKGCHNQLVSIRAFLLKRQTVQGKLGQMFRELVILLEAIDAT", "md5" : "e2a257493db06c7d4998de408daf1931", "matches" : [ { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 140, "end" : 181, "score" : 19.264, "alignment" : "YRGHIGSVNSVKFSPDGQWIASGGEDSTVKIWDLRTGSVLHD", "location-fragments" : [ { "start" : 140, "end" : 181, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 460, "end" : 513, "location-fragments" : [ { "start" : 460, "end" : 513, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 392, "end" : 408, "location-fragments" : [ { "start" : 392, "end" : 408, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS00678", "name" : "WD_REPEATS_1", "description" : "Trp-Asp (WD) repeats signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019775", "name" : "WD40_repeat_CS", "description" : "WD40 repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 201, "end" : 215, "level" : "STRONG", "cigarAlignment" : "4M2I1M1I7M", "alignment" : "LASSstDkTVHFWDL", "location-fragments" : [ { "start" : 201, "end" : 215, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00678" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 94, "end" : 171, "hmmStart" : 56, "hmmEnd" : 135, "hmmLength" : 330, "hmmBounds" : "INCOMPLETE", "evalue" : 4.4E-30, "score" : 106.9, "envelopeStart" : 90, "envelopeEnd" : 174, "postProcessed" : true, "location-fragments" : [ { "start" : 94, "end" : 171, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-76, "score" : 259.3, "model-ac" : "2xzmR01" }, { "signature" : { "accession" : "SM00320", "name" : "WD40_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 219, "end" : 257, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 180.0, "score" : 2.7, "location-fragments" : [ { "start" : 219, "end" : 257, "dc-status" : "CONTINUOUS" } ] }, { "start" : 175, "end" : 214, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 3.2E-8, "score" : 43.3, "location-fragments" : [ { "start" : 175, "end" : 214, "dc-status" : "CONTINUOUS" } ] }, { "start" : 6, "end" : 46, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 7.1E-5, "score" : 32.2, "location-fragments" : [ { "start" : 6, "end" : 46, "dc-status" : "CONTINUOUS" } ] }, { "start" : 133, "end" : 172, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-13, "score" : 60.9, "location-fragments" : [ { "start" : 133, "end" : 172, "dc-status" : "CONTINUOUS" } ] }, { "start" : 91, "end" : 130, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 5.9E-9, "score" : 45.8, "location-fragments" : [ { "start" : 91, "end" : 130, "dc-status" : "CONTINUOUS" } ] }, { "start" : 49, "end" : 88, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-7, "score" : 41.6, "location-fragments" : [ { "start" : 49, "end" : 88, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-63, "score" : 226.5, "model-ac" : "SM00320" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 55, "score" : 11.712, "alignment" : "FTAHTAPVNCLALGHKsGRVLVTGGDDKKVNLWAVGKENCIMS", "location-fragments" : [ { "start" : 13, "end" : 55, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "PS00678", "name" : "WD_REPEATS_1", "description" : "Trp-Asp (WD) repeats signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019775", "name" : "WD40_repeat_CS", "description" : "WD40 repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 75, "end" : 89, "level" : "STRONG", "cigarAlignment" : "4M2I1M1I7M", "alignment" : "VCAGsrDgVLKVWDL", "location-fragments" : [ { "start" : 75, "end" : 89, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00678" }, { "signature" : { "accession" : "SSF50978", "name" : "WD40 repeat-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036322", "name" : "WD40_repeat_dom_sf", "description" : "WD40-repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 265, "hmmLength" : 317, "location-fragments" : [ { "start" : 8, "end" : 265, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.14E-70, "model-ac" : "0053623" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 98, "end" : 139, "score" : 15.454, "alignment" : "LIGHQDCMKSVDFHPYAEFLASGSVDSTIKLWDIRKKGCIFT", "location-fragments" : [ { "start" : 98, "end" : 139, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "PS00678", "name" : "WD_REPEATS_1", "description" : "Trp-Asp (WD) repeats signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019775", "name" : "WD40_repeat_CS", "description" : "WD40 repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 117, "end" : 131, "level" : "STRONG", "cigarAlignment" : "4M2I1M1I7M", "alignment" : "LASGsvDsTIKLWDI", "location-fragments" : [ { "start" : 117, "end" : 131, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00678" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 322, "end" : 439, "location-fragments" : [ { "start" : 322, "end" : 439, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5, "end" : 93, "hmmStart" : 109, "hmmEnd" : 197, "hmmLength" : 366, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.5E-21, "score" : 77.2, "envelopeStart" : 5, "envelopeEnd" : 97, "postProcessed" : true, "location-fragments" : [ { "start" : 5, "end" : 93, "dc-status" : "CONTINUOUS" } ] }, { "start" : 172, "end" : 330, "hmmStart" : 98, "hmmEnd" : 201, "hmmLength" : 366, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.9E-16, "score" : 61.7, "envelopeStart" : 169, "envelopeEnd" : 330, "postProcessed" : true, "location-fragments" : [ { "start" : 172, "end" : 330, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-74, "score" : 252.8, "model-ac" : "3k26A00" }, { "signature" : { "accession" : "cd00200", "name" : "WD40", "description" : "WD40", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 214, "sites" : [ ], "evalue" : 9.41288E-66, "score" : 219.514, "location-fragments" : [ { "start" : 10, "end" : 214, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00200" }, { "signature" : { "accession" : "PS00678", "name" : "WD_REPEATS_1", "description" : "Trp-Asp (WD) repeats signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019775", "name" : "WD40_repeat_CS", "description" : "WD40 repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 159, "end" : 173, "level" : "STRONG", "cigarAlignment" : "4M2I1M1I7M", "alignment" : "IASGgeDsTVKIWDL", "location-fragments" : [ { "start" : 159, "end" : 173, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00678" }, { "signature" : { "accession" : "PTHR19845", "name" : "KATANIN P80 SUBUNIT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 838, "hmmStart" : 1, "hmmEnd" : 753, "hmmLength" : 756, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 841, "location-fragments" : [ { "start" : 1, "end" : 838, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-198, "familyName" : "KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1", "score" : 663.3, "model-ac" : "PTHR19845" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 460, "end" : 506, "location-fragments" : [ { "start" : 460, "end" : 506, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 182, "end" : 223, "score" : 13.583, "alignment" : "FIKHDGPVLSVEYHPHEFLLASSSTDKTVHFWDLDKFTSISA", "location-fragments" : [ { "start" : 182, "end" : 223, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "MF_03022", "name" : "Katanin_p80_B1", "description" : "Katanin p80 WD40 repeat-containing subunit B1 [KATNB1].", "signatureLibraryRelease" : { "library" : "HAMAP", "version" : "2020_01" }, "entry" : { "accession" : "IPR026962", "name" : "Katanin_bsu1", "description" : "Katanin p80 subunit B1", "type" : "FAMILY", "goXRefs" : [ { "name" : "microtubule severing", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0051013" }, { "name" : "katanin complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0008352" }, { "name" : "microtubule binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008017" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 841, "score" : 19.649, "alignment" : "EVAQRSWRLVEFTAHTAPVNCLALGHKSGRVLVTGGDDKKVNLWAVGKENCIMSLSGHGTPIETVRFSSSEDMVCAGSRDGVLKVWDLEAAKIVRTLIGHQDCMKSVDFHPYAEFLASGSVDSTIKLWDIRKKGCIFTYRGHIGSVNSVKFSPDGQWIASGGEDSTVKIWDLRTGSVLHDFIKHDGPVLSVEYHPHEFLLASSSTDKTVHFWDLDKFTSISAT--EkqahAS--RCIRFSEGGECLFAGACDTLNVFGWEPLRSLDTVFTQWSKIRDISTVGSQLIGAGYQAEGVMIYVVDLAKVcpigKPL-----PPA-------S---P--FAHGMSIRKSFNKQKPAPKSTAVKHQK------------------PIEENE-TEPEDENLADIPD---VNnYEAVFCPNRTLNRSPPPNEelfTPpgNiTElnaP-----AQ----TSlhSgSQlaaET-EeeyyeetepspkdhApksiyvskNKQSsssevmsPvSSsichTVS----TlTSgmthtapgqN-HssmpaslNslsPtssSD-----HSfsrlgS-ANhadsskearsQsyddPskilaRainfypkirTSE-YrilcrktigkikNmpgplkattkrfiaSlkthRVcnfES-S-P---SE-PaIS--N-S-ArkvgngIgVkvsnnhkPElppKpkyqlsvkqhqnnaKNimmkpgkRPgAgeddnieyiPMtgDtpvglEPnEFLP-----KRG----SGgQ----LSEAEVISSVMRGHEDMMRVLISRQRNLQIIFSVWHTKDLKSAVEMATDMNDLSVVVDLLSALTRKPNLWSLDLCNLLLPSIRELLQSKYETYVTVGCDALRLILRNFSSVIRNNVQWSCPTIGVDITKEERYNKCKGCHNQLVSIRAFLLKRQTVQGKLGQMFRELVILLEAI", "location-fragments" : [ { "start" : 2, "end" : 841, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "MF_03022" }, { "signature" : { "accession" : "PS50294", "name" : "WD_REPEATS_REGION", "description" : "Trp-Asp (WD) repeats circular profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR017986", "name" : "WD40_repeat_dom", "description" : "WD40-repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 223, "score" : 58.108, "alignment" : "FTAHTAPVNCLALGHKsGRVLVTGGDDKKVNLWAVGKENCIMSLSGHGTPIETVRFSSSEDMVCAGSRDGVLKVWDLEAAKIVRTLIGHQDCMKSVDFHPYAEFLASGSVDSTIKLWDIRKKGCIFTYRGHIGSVNSVKFSPDGQWIASGGEDSTVKIWDLRTGSVLHDFIKHDGPVLSVEYHPHEFLLASSSTDKTVHFWDLDKFTSISA", "location-fragments" : [ { "start" : 13, "end" : 223, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50294" }, { "signature" : { "accession" : "PTHR19845:SF0", "name" : "KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 838, "hmmStart" : 1, "hmmEnd" : 753, "hmmLength" : 756, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 841, "location-fragments" : [ { "start" : 1, "end" : 838, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-198, "familyName" : "KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1", "score" : 663.3, "model-ac" : "PTHR19845:SF0" }, { "signature" : { "accession" : "PR00320", "name" : "GPROTEINBRPT", "description" : "G protein beta WD-40 repeat signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR020472", "name" : "G-protein_beta_WD-40_rep", "description" : "G-protein beta WD-40 repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 117, "end" : 131, "pvalue" : 3.01E-6, "score" : 46.62, "motifNumber" : 2, "location-fragments" : [ { "start" : 117, "end" : 131, "dc-status" : "CONTINUOUS" } ] }, { "start" : 159, "end" : 173, "pvalue" : 9.95E-6, "score" : 41.23, "motifNumber" : 3, "location-fragments" : [ { "start" : 159, "end" : 173, "dc-status" : "CONTINUOUS" } ] }, { "start" : 75, "end" : 89, "pvalue" : 1.53E-4, "score" : 35.08, "motifNumber" : 1, "location-fragments" : [ { "start" : 75, "end" : 89, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-9, "graphscan" : "III", "model-ac" : "PR00320" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 56, "end" : 97, "score" : 15.488, "alignment" : "LSGHGTPIETVRFSSSEDMVCAGSRDGVLKVWDLEAAKIVRT", "location-fragments" : [ { "start" : 56, "end" : 97, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "PF13925", "name" : "Katanin_con80", "description" : "con80 domain of Katanin", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR028021", "name" : "Katanin_C-terminal", "description" : "Katanin p80 subunit, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 680, "end" : 836, "hmmStart" : 2, "hmmEnd" : 158, "hmmLength" : 160, "hmmBounds" : "INCOMPLETE", "evalue" : 1.1E-53, "score" : 181.6, "envelopeStart" : 679, "envelopeEnd" : 838, "postProcessed" : true, "location-fragments" : [ { "start" : 680, "end" : 836, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-54, "score" : 182.3, "model-ac" : "PF13925" }, { "signature" : { "accession" : "PF00400", "name" : "WD40", "description" : "WD domain, G-beta repeat", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 11, "end" : 45, "hmmStart" : 5, "hmmEnd" : 37, "hmmLength" : 38, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-4, "score" : 22.2, "envelopeStart" : 7, "envelopeEnd" : 45, "postProcessed" : true, "location-fragments" : [ { "start" : 11, "end" : 45, "dc-status" : "CONTINUOUS" } ] }, { "start" : 136, "end" : 172, "hmmStart" : 3, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.3E-13, "score" : 49.5, "envelopeStart" : 134, "envelopeEnd" : 172, "postProcessed" : true, "location-fragments" : [ { "start" : 136, "end" : 172, "dc-status" : "CONTINUOUS" } ] }, { "start" : 94, "end" : 130, "hmmStart" : 3, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.1E-7, "score" : 32.4, "envelopeStart" : 92, "envelopeEnd" : 130, "postProcessed" : true, "location-fragments" : [ { "start" : 94, "end" : 130, "dc-status" : "CONTINUOUS" } ] }, { "start" : 51, "end" : 88, "hmmStart" : 2, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.0E-7, "score" : 31.5, "envelopeStart" : 50, "envelopeEnd" : 88, "postProcessed" : true, "location-fragments" : [ { "start" : 51, "end" : 88, "dc-status" : "CONTINUOUS" } ] }, { "start" : 177, "end" : 214, "hmmStart" : 2, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 0.0012, "score" : 19.6, "envelopeStart" : 176, "envelopeEnd" : 214, "postProcessed" : true, "location-fragments" : [ { "start" : 177, "end" : 214, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-44, "score" : 148.5, "model-ac" : "PF00400" } ], "xref" : [ { "name" : "XP_018910096.1 PREDICTED: katanin p80 WD40 repeat-containing subunit B1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910096.1" }, { "name" : "XP_018910097.1 PREDICTED: katanin p80 WD40 repeat-containing subunit B1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910097.1" } ] },{ "sequence" : "MAEIRENPLGDEHVLSLELKQCGTTTTTTGVEKDGEKEAPARGSWSSKIDFILSVVGLAVGLGNVWRFPYLCYKNGGGAFLVPYLIALFLAGIPMFFMELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAIFYFVMSIRIDVPWRTCNNYWNTKYCVSPYERIGLKCWNTTTHGSICNLNNYNVSIKDLSDPVKEFWERRALQITTGVQQVGEIRWELAGTLFFVWLLCYFCIWKGVKWTGKVVYFTALFPYFLLTVLLIRGITLPGAIDGIKYYVKPNLSKLGESQVWIDAVTQIFFSYGLGLGTLVALGSYNKFNNDVYKDALIVCCVNSGTSMFAGFVIFSVIGFMAHEQHKPVGEVAASGPGLAFLAYPSAVLQLPWSSLWSCLFFVMLLFIGLDSQFCTMEGFITAMVDEYPRLLRRRKEVFIAIVCILSYLAGFSCISQGGMYVFQLLDSYAVSGFCLLFLIFFECVSISWAFGVNRFYDGIKEMIGYYPCWFWKYCWLFSCPIICISVFFFNLIQWTPIKYLNYEYPWWSHVFGWFTALSSMLCIPGYMIYAWMTTPGDFDEKFRKLVRIEDDVATLRLKMGHKAEPKEDGKSDMI", "md5" : "78dbbfac2c240cbfc9cb0133df9db7af", "matches" : [ { "signature" : { "accession" : "PTHR11616", "name" : "SODIUM/CHLORIDE DEPENDENT TRANSPORTER", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR000175", "name" : "Na/ntran_symport", "description" : "Sodium:neurotransmitter symporter", "type" : "FAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 28, "end" : 594, "hmmStart" : 35, "hmmEnd" : 573, "hmmLength" : 577, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 602, "location-fragments" : [ { "start" : 28, "end" : 594, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-282, "familyName" : "TRANSPORTER", "score" : 939.0, "model-ac" : "PTHR11616" }, { "signature" : { "accession" : "cd11496", "name" : "SLC6sbd-TauT-like", "description" : "SLC6sbd-TauT-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 42, "end" : 592, "sites" : [ { "description" : "putative substrate binding site 2", "numLocations" : 7, "siteLocations" : [ { "start" : 67, "end" : 67, "residue" : "R" }, { "start" : 141, "end" : 141, "residue" : "I" }, { "start" : 66, "end" : 66, "residue" : "W" }, { "start" : 144, "end" : 144, "residue" : "W" }, { "start" : 380, "end" : 380, "residue" : "P" }, { "start" : 137, "end" : 137, "residue" : "Y" }, { "start" : 384, "end" : 384, "residue" : "F" } ] }, { "description" : "Na binding site 2", "numLocations" : 5, "siteLocations" : [ { "start" : 414, "end" : 414, "residue" : "D" }, { "start" : 57, "end" : 57, "residue" : "G" }, { "start" : 60, "end" : 60, "residue" : "V" }, { "start" : 415, "end" : 415, "residue" : "S" }, { "start" : 411, "end" : 411, "residue" : "I" } ] }, { "description" : "Na binding site 1", "numLocations" : 4, "siteLocations" : [ { "start" : 59, "end" : 59, "residue" : "A" }, { "start" : 346, "end" : 346, "residue" : "N" }, { "start" : 64, "end" : 64, "residue" : "N" }, { "start" : 314, "end" : 314, "residue" : "S" } ] }, { "description" : "putative substrate binding site 1", "numLocations" : 14, "siteLocations" : [ { "start" : 58, "end" : 58, "residue" : "L" }, { "start" : 313, "end" : 313, "residue" : "F" }, { "start" : 59, "end" : 59, "residue" : "A" }, { "start" : 319, "end" : 319, "residue" : "L" }, { "start" : 138, "end" : 138, "residue" : "Y" }, { "start" : 321, "end" : 321, "residue" : "T" }, { "start" : 64, "end" : 64, "residue" : "N" }, { "start" : 62, "end" : 62, "residue" : "L" }, { "start" : 419, "end" : 419, "residue" : "T" }, { "start" : 63, "end" : 63, "residue" : "G" }, { "start" : 415, "end" : 415, "residue" : "S" }, { "start" : 418, "end" : 418, "residue" : "C" }, { "start" : 314, "end" : 314, "residue" : "S" }, { "start" : 61, "end" : 61, "residue" : "G" } ] } ], "evalue" : 0.0, "score" : 880.762, "location-fragments" : [ { "start" : 42, "end" : 592, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd11496" }, { "signature" : { "accession" : "PF00209", "name" : "SNF", "description" : "Sodium:neurotransmitter symporter family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000175", "name" : "Na/ntran_symport", "description" : "Sodium:neurotransmitter symporter", "type" : "FAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 577, "hmmStart" : 1, "hmmEnd" : 522, "hmmLength" : 523, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 8.9E-220, "score" : 730.8, "envelopeStart" : 42, "envelopeEnd" : 578, "postProcessed" : true, "location-fragments" : [ { "start" : 42, "end" : 577, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.7E-220, "score" : 731.0, "model-ac" : "PF00209" }, { "signature" : { "accession" : "PTHR11616:SF265", "name" : "TRANSPORTER", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 28, "end" : 594, "hmmStart" : 35, "hmmEnd" : 573, "hmmLength" : 577, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 602, "location-fragments" : [ { "start" : 28, "end" : 594, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-282, "familyName" : "TRANSPORTER", "score" : 939.0, "model-ac" : "PTHR11616:SF265" }, { "signature" : { "accession" : "PS50267", "name" : "NA_NEUROTRAN_SYMP_3", "description" : "Sodium:neurotransmitter symporter family profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000175", "name" : "Na/ntran_symport", "description" : "Sodium:neurotransmitter symporter", "type" : "FAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 41, "end" : 580, "score" : 108.954, "alignment" : "ARGSWSSKIDFILSVVGLAVGLGNVWRFPYLCYKNGGGAFLVPYLIALFLAGIPMFFMELALGQMLTIGGLGVFK-IAPIFKGIGYAAAVMSCWMNVYYIVILAWAIFYFVMSiridvpwrtcnnywntkycvspyeriglkcwnttthgsicnlnnynvsikdlsDPVKEFWERRALQITTGVQQVGEIRWELAGTLFFVWLLCYFCIWKGVKWTGKVVYFTALFPYFLLTVLLIRGITLPGAIDGIKYYVKPNLSKLGESQVWIDAVTQIFFSYGLGLGTLVALGSYNKFNNDVYKDALIVCCVNSGTSMFAGFVIFSVIGFMAheqhkpvgEVAASGPGLAFLAYPSAVLQLPWSSLWSCLFFVMLLFIGLDSQFCTMEGFITAMVDEYPRLLRRRKEVFIAIVCILSYLAGFSCISQGGMYVFQLLDSYAVsGFCLLFLIFFECVSISWAFGVNRFYDGIKEMIGYYPCWFWKYCWLFSCPIICISVFFFNLIQWTPIKYLN-YEYPWWSHVFGWFTALSSMLCIPGYMIYAWMTTPG", "location-fragments" : [ { "start" : 41, "end" : 580, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50267" }, { "signature" : { "accession" : "SSF161070", "name" : "SNF-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR037272", "name" : "SNS_sf", "description" : "Sodium:neurotransmitter symporter superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 576, "hmmLength" : 509, "location-fragments" : [ { "start" : 206, "end" : 576, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 42, "end" : 171, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 8.37E-176, "model-ac" : "0053687" }, { "signature" : { "accession" : "PS00610", "name" : "NA_NEUROTRAN_SYMP_1", "description" : "Sodium:neurotransmitter symporter family signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000175", "name" : "Na/ntran_symport", "description" : "Sodium:neurotransmitter symporter", "type" : "FAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 66, "end" : 80, "level" : "STRONG", "cigarAlignment" : "5M4I4M1I1M", "alignment" : "WRFPYlcykNGGGaF", "location-fragments" : [ { "start" : 66, "end" : 80, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00610" }, { "signature" : { "accession" : "PR00176", "name" : "NANEUSMPORT", "description" : "Sodium/chloride neurotransmitter symporter signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000175", "name" : "Na/ntran_symport", "description" : "Sodium:neurotransmitter symporter", "type" : "FAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 79, "end" : 98, "pvalue" : 2.81E-12, "score" : 55.16, "motifNumber" : 2, "location-fragments" : [ { "start" : 79, "end" : 98, "dc-status" : "CONTINUOUS" } ] }, { "start" : 394, "end" : 413, "pvalue" : 2.76E-10, "score" : 55.49, "motifNumber" : 6, "location-fragments" : [ { "start" : 394, "end" : 413, "dc-status" : "CONTINUOUS" } ] }, { "start" : 258, "end" : 275, "pvalue" : 3.35E-11, "score" : 62.84, "motifNumber" : 4, "location-fragments" : [ { "start" : 258, "end" : 275, "dc-status" : "CONTINUOUS" } ] }, { "start" : 476, "end" : 496, "pvalue" : 1.88E-10, "score" : 43.72, "motifNumber" : 7, "location-fragments" : [ { "start" : 476, "end" : 496, "dc-status" : "CONTINUOUS" } ] }, { "start" : 50, "end" : 71, "pvalue" : 4.98E-14, "score" : 75.26, "motifNumber" : 1, "location-fragments" : [ { "start" : 50, "end" : 71, "dc-status" : "CONTINUOUS" } ] }, { "start" : 340, "end" : 360, "pvalue" : 1.91E-13, "score" : 55.27, "motifNumber" : 5, "location-fragments" : [ { "start" : 340, "end" : 360, "dc-status" : "CONTINUOUS" } ] }, { "start" : 122, "end" : 148, "pvalue" : 1.37E-14, "score" : 50.27, "motifNumber" : 3, "location-fragments" : [ { "start" : 122, "end" : 148, "dc-status" : "CONTINUOUS" } ] }, { "start" : 516, "end" : 536, "pvalue" : 1.67E-7, "score" : 34.82, "motifNumber" : 8, "location-fragments" : [ { "start" : 516, "end" : 536, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-83, "graphscan" : "IIIIIIII", "model-ac" : "PR00176" } ], "xref" : [ { "name" : "XP_018909657.1 PREDICTED: sodium- and chloride-dependent GABA transporter 1-like [Bemisia tabaci]", "id" : "XP_018909657.1" } ] },{ "sequence" : "MPLDISSIETGLKQSIKNLNNTVTQTKQMIENIATTEASLDVKIEKRQVDLERNKKRLESLKKVRPSFLEEYEKLEKDFKELYEAYVVRYRCVAYLEQQLEEFEQATQSRIDAKHEETRKLVEKMRQEAAAKLFDGTIEDEGQAANGAQTAGTGSRMVGGKRRVFGSMTGGGDDLGSSDSDSDLFFDDDDDNDDDDDEDDDDDDDDEDDDDGRHDEDHDKNADRGDGDY", "md5" : "5b709a7851774e1945798aacfa18a3ae", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 180, "end" : 213, "location-fragments" : [ { "start" : 180, "end" : 213, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR21547", "name" : "CLUSTERIN ASSOCIATED PROTEIN 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR019366", "name" : "Clusterin-associated_protein-1", "description" : "Clusterin-associated protein-1", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Intraflagellar transport", "databaseName" : "Reactome", "id" : "R-HSA-5620924" } ] } }, "locations" : [ { "start" : 2, "end" : 215, "hmmStart" : 175, "hmmEnd" : 401, "hmmLength" : 409, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 229, "location-fragments" : [ { "start" : 2, "end" : 215, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-46, "familyName" : "CLUSTERIN ASSOCIATED PROTEIN 1", "score" : 162.3, "model-ac" : "PTHR21547" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 58, "end" : 78, "location-fragments" : [ { "start" : 58, "end" : 78, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF10234", "name" : "Cluap1", "description" : "Clusterin-associated protein-1", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR019366", "name" : "Clusterin-associated_protein-1", "description" : "Clusterin-associated protein-1", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Intraflagellar transport", "databaseName" : "Reactome", "id" : "R-HSA-5620924" } ] } }, "locations" : [ { "start" : 2, "end" : 109, "hmmStart" : 160, "hmmEnd" : 267, "hmmLength" : 268, "hmmBounds" : "INCOMPLETE", "evalue" : 3.1E-34, "score" : 118.6, "envelopeStart" : 1, "envelopeEnd" : 110, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 109, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-34, "score" : 119.2, "model-ac" : "PF10234" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 214, "end" : 229, "location-fragments" : [ { "start" : 214, "end" : 229, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 96, "end" : 116, "location-fragments" : [ { "start" : 96, "end" : 116, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 144, "end" : 229, "location-fragments" : [ { "start" : 144, "end" : 229, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910129.1 PREDICTED: clusterin-associated protein 1 homolog [Bemisia tabaci]", "id" : "XP_018910129.1" } ] },{ "sequence" : "MTKKKESASTSSEKTSKSSNETKSTTESKSNESSSNRKSSLTSRILGPFSRASSTASVASQKDSKSATDRKLSLVKIESIDDDDDLANLTVPKTIEYTVTEPATLVVEKKDTSQKTKSKNAKTNKSVIESVKMVGGKIIKTTKAMQFTFARPDDDDNDDDDFQVEITEIPSEERRASVGSTHFSERKMSADFSAESKSKVFQSSKSDSQSSFYSTHDSSTADEQNVRLVGGKLTKTPSKDSQSQSNSKVEGSDSQLTRTSSHRLIEKQSSQKSIHESSQESVKESKATTVQKSGSRTYITTKTTIGPDGKERTETVVKKEELPPESQTTYSEKQESKKAENFSTTGQSNLKLTTGSADDKSYSARLRASLEDDTSGTSKNSELSSVKIVKTASDSSSKTFKTEKVFETSDSRSSVYSDSQSFIQNEKSGVTDKLSSSTDASNKGASSDTAIRSKDDVNYYTSGTSYVTTTTTGAKQSQDTSGVRLVGGKIVKTTESKDYFNKKIGDGLDKKSSRSTESPSNALSNQSDTMSSSKLVSSIDKSASHTTDSLSKVTDKTESMSSTKLVSSADKQSIYSTKTNVSTDKFENIPSSQLVSSIDKTATHTTDFPGKSTVDTMDGVSSSILVSSIDSQSKNISDRSESFSTSKVSSSKSEIKTSKVDSSSTAYSSDVFDFSDENLVCTCDLGATHSTNDFSHKDEISSTKFLKSENSKTSTTQFVSGVPVGFDPAPLDIPKSPKQPKSPTTKLVGGKLVKLGEDKDYFNKKISEGVEKKELRTTDSSSKFDVEETSVTYVTDKFSSKLSSSSIVDQQSKSFDKETNSFGTRLVGGKLVKDSTDATYYNQKMTDGFEKKIQDSTSTDKSYTKDSTYTVTSDFISRESEKQFDLGRNDVTYTSEKTIPRSKITDDTYSLIKTQNGSIPTSTTEKTYIIDASTNSQEVKMVGGKIVKNVSDKNYYNQKITDGLKKKDSEKTKTDSTTFKTQKDISSHDFAKTDFSSSNTFTTQKFEVSDISDKHVSDKTYVKTLSKEFPISGSPQGPVEPGLTVKMVGGKLVKTFVTPEPQPKKKPGREPSPTKYSTDQTFAVESETISSYKQKELKNGDIKKFPRTETTTIIKNIGDTTDYNISTAELRSTTKEQVSNYTSKYISEYDQGRPRDTSPTKVRRDDSPSKSKPKDYSPLKARDVSPTKSKPRDTSPTKLGKDKSPIRSVSQIRPDTTITSKTTDKRSDFSLDRSDTTVVSSSFVSENLYINDYRSTDSVNQTKLVTSTPIKPGRKEPSDKSPKDEGPKKPSDRSPTTTKPTVESTKSTTEIPETGLTVKMVGGKLVKTFVTPEPAPKKKPEREPSPTKSPKPKRTDMLDKPETYSPTAIRKGSYTITSTGEKVGDRPVALVPRDYDVVDRSYTSASSDTFQASTNFKTESQTTYATSKVLKESFVYDSRGNVVKVTKTESVQDLKPETVSRTSVTSDVKATRLVDERVVDNRETSVTKTVRDDRKTIDKKTVRDDKKTVRDDKKTTKVTEKTVVKEQCICEICTCGRHTCTHEPENTGPPLDWKPEPVPKTSLKNEAFHPFKPNEVERPKIQRLNTELELPQGEIDQTTNYKKDYPEKHAERQPRYHMEDHLHLEGEYKVTRKQEYTATKGERAPVRKPEDNLRPEGEFERPKPEKFGPAERPKPFKPSDNLKPEGEFERPKPEKVGPGERAPIVKHPDNLWPEGDFQRPEKDQFKPAERPKQVRPSDNLKPEGDFDRPEKEKFRPAERPKQVKPSDNLKPEGDFDRPEKDKFRPAERPKQVKPTDNLKPEGEFERPKPETLGPAERPKPIKPTDNLKPEGDFERPGKDQFKPAERPKQVKPTDNLKPEGEFDRPVKETAPKKGERAPVKRPEDNLKPEGEFYGERVVTKVVKGERAEIKHHEDHLKTEGEFYGITTKQIEFTGEPGERPNMIRRNTWTKLEGDMEIETTNKSEFKKFDTTRTTIIRRHTDNLTVGEGTIQITSQNREDYPERRVVKPEKPKKRPDNLKPDGGEFYSETSSMQAFQGQTVTSRVEITRHKDNLTSEGDITFITSSQTDYTEKLPERETPKRRRTWTKQDGERYFETTHTQEFKTYENITDVRQTQKRHHDNLKPEGPFEGTPRSKDDFKPVTAERPVQKKPRDNLKPEGDFQRPEKEKFKPAERPKQVKPTDNLKPEGEIQRPRKEEFKPSERPKPVKPSDNLKPEGDFERPEKDKFKPAERPKQVKPTDNLKPEGDFERPEKGQFRPAERPKQVKPTDNLKPEGDFQRPEKDQFRPAERPKQKKPTDNLRPEGDFERPEKDKFRPAERPKQVKPTDNLKPEGDFERPEREQFRPAERPKQVKPTDNLKPEGDFERPEKDTFKPVERPSPVKPTDNLKPEGDFQRPEKDQIRPAERPKQVKPSDNLKPEGDFERPEKDQFRPAERPKQVKPSDNLKPEGDFERPEKDHFRPAERPVPVKPSDNLKPEGDFERPEKRQFKPAERPKQVKPTDNLKPEGDFERPEKDKFKPAERPTPVKPSDNLRPEGDFQRPEKEQFTPAERPKQVKPSDNLKPEGEFERPEKDHFKPAERPKQMKPSDNLKPEGDFERPEREQFKPVERPKAVKPSDNLKPEGDFDRPVKGQFTPAERPKQVKPSDNLRPEGEFERPERDQFKSAERPKQVKPTDNLKPEGEFDRPEKAPFTPGERPKAVKPCDNLYPEGDFERPEKPVVGPGERAPIVRHPDNLFPEGDFEQTPKDKVIPKGERAPVVKPKDNLYPEGEFEKRPTNDFLPEKGERAPIVIPQDNLKPEGEFEGRPKPKEGPTYGERAPVVKPKDNLYPEGKFVRPEPEYAPTHGERAPTKKYPDNLKPEGDIDFPIREAPTPTKGDRAPVKKPKDNLYPEGEFQKRPKGELPRGERAPVVKPKDNLWPEGEFEKRPTNDFPPKKGERAPIVIPKDNLKPEGEFEGRPKPKDEPIYGERAPVVKPKDNLYPEGKFVRPEPEYAPTHGERAPTKKYPDNLKPEGDIDFPMREAPKPTKGDRAPVKKPKDNLYPEGEFQKRPKEELPRGERAPVVKPKDNLWPEGEFERPPLPEYSSVKRPEPFKPSDNLKPEGEFERPQPKKVGPGERADIIKHPDNLKPEGEFIGRPKQEPVPTYGERAPVVKPKDNLYPEGDFVRPEPEITPTKGDRAPTKRHPDNLKPEGEFTGRPKDDFKPTKGERAPTKKPQDNLFPEGDFERPEPVKYGPGERPKPVKPSDNLKPEGDFERPVKEAFKPAERPKQVKPEDNLRPEGDFERPVKQPVGPGERAPIIKHPDNLRPEGDFERPEKDQFKPAERPKPVKPTDNLKPEGEFEKRTPTKVGPGERAPIIKHEDNLRPEGDFERPEKEGYRPAERPKPIKPSDNLKPEGDFDRPIKEKVGPGERAPIIKHPDNLRPEGNFERPEKDQFKPAERPKQVKPTDNLKPEGDFERPEREGFKPAERPKQVKPSDNLKPEGDFERPEKERFKPAERPTPVKPSDNLKPEGDFERPEKEKFKPAERPKQVKPSDNLKPEGDFERPEKEKFKPAER", "md5" : "470263e0c98338f09c3d231a5d6a3f4b", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 514, "end" : 541, "location-fragments" : [ { "start" : 514, "end" : 541, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 502, "end" : 541, "location-fragments" : [ { "start" : 502, "end" : 541, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR31516", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR033336", "name" : "SAXO1/2", "description" : "Stabilizer of axonemal microtubules 1/2", "type" : "FAMILY", "goXRefs" : [ { "name" : "microtubule binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008017" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1641, "end" : 2029, "hmmStart" : 1432, "hmmEnd" : 1802, "hmmLength" : 3942, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1639, "envelopeEnd" : 2035, "location-fragments" : [ { "start" : 1641, "end" : 2029, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "", "score" : 2705.6, "model-ac" : "PTHR31516" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 3242, "end" : 3285, "location-fragments" : [ { "start" : 3242, "end" : 3285, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1927, "end" : 1946, "location-fragments" : [ { "start" : 1927, "end" : 1946, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1600, "end" : 1702, "location-fragments" : [ { "start" : 1600, "end" : 1702, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 340, "end" : 360, "location-fragments" : [ { "start" : 340, "end" : 360, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2388, "end" : 2465, "location-fragments" : [ { "start" : 2388, "end" : 2465, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1058, "end" : 1080, "location-fragments" : [ { "start" : 1058, "end" : 1080, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2980, "end" : 3073, "location-fragments" : [ { "start" : 2980, "end" : 3073, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2875, "end" : 2970, "location-fragments" : [ { "start" : 2875, "end" : 2970, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR31516", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR033336", "name" : "SAXO1/2", "description" : "Stabilizer of axonemal microtubules 1/2", "type" : "FAMILY", "goXRefs" : [ { "name" : "microtubule binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008017" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2855, "end" : 3139, "hmmStart" : 1413, "hmmEnd" : 1688, "hmmLength" : 3942, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 2855, "envelopeEnd" : 3143, "location-fragments" : [ { "start" : 2855, "end" : 3139, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2001, "end" : 2340, "hmmStart" : 1717, "hmmEnd" : 2006, "hmmLength" : 3942, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1998, "envelopeEnd" : 2341, "location-fragments" : [ { "start" : 2001, "end" : 2340, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "", "score" : 2705.6, "model-ac" : "PTHR31516" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1149, "end" : 1200, "location-fragments" : [ { "start" : 1149, "end" : 1200, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2828, "end" : 2865, "location-fragments" : [ { "start" : 2828, "end" : 2865, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 307, "end" : 321, "location-fragments" : [ { "start" : 307, "end" : 321, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 283, "end" : 306, "location-fragments" : [ { "start" : 283, "end" : 306, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 3092, "end" : 3135, "location-fragments" : [ { "start" : 3092, "end" : 3135, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2474, "end" : 2523, "location-fragments" : [ { "start" : 2474, "end" : 2523, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 72, "location-fragments" : [ { "start" : 1, "end" : 72, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1994, "end" : 2026, "location-fragments" : [ { "start" : 1994, "end" : 2026, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR31516", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR033336", "name" : "SAXO1/2", "description" : "Stabilizer of axonemal microtubules 1/2", "type" : "FAMILY", "goXRefs" : [ { "name" : "microtubule binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008017" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2289, "end" : 2521, "hmmStart" : 1810, "hmmEnd" : 2042, "hmmLength" : 3942, "hmmBounds" : "COMPLETE", "envelopeStart" : 2289, "envelopeEnd" : 2521, "location-fragments" : [ { "start" : 2289, "end" : 2521, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "", "score" : 2705.6, "model-ac" : "PTHR31516" }, { "signature" : { "accession" : "PTHR31516:SF16", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2753, "end" : 2991, "hmmStart" : 1403, "hmmEnd" : 1630, "hmmLength" : 3942, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2747, "envelopeEnd" : 2995, "location-fragments" : [ { "start" : 2753, "end" : 2991, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2513, "end" : 2751, "hmmStart" : 1802, "hmmEnd" : 2040, "hmmLength" : 3942, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 2513, "envelopeEnd" : 2757, "location-fragments" : [ { "start" : 2513, "end" : 2751, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "", "score" : 2705.6, "model-ac" : "PTHR31516:SF16" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2070, "end" : 2099, "location-fragments" : [ { "start" : 2070, "end" : 2099, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR31516", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR033336", "name" : "SAXO1/2", "description" : "Stabilizer of axonemal microtubules 1/2", "type" : "FAMILY", "goXRefs" : [ { "name" : "microtubule binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008017" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2753, "end" : 2991, "hmmStart" : 1403, "hmmEnd" : 1630, "hmmLength" : 3942, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2747, "envelopeEnd" : 2995, "location-fragments" : [ { "start" : 2753, "end" : 2991, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3062, "end" : 3331, "hmmStart" : 1408, "hmmEnd" : 1672, "hmmLength" : 3942, "hmmBounds" : "COMPLETE", "envelopeStart" : 3062, "envelopeEnd" : 3331, "location-fragments" : [ { "start" : 3062, "end" : 3331, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2513, "end" : 2751, "hmmStart" : 1802, "hmmEnd" : 2040, "hmmLength" : 3942, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 2513, "envelopeEnd" : 2757, "location-fragments" : [ { "start" : 2513, "end" : 2751, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3301, "end" : 3557, "hmmStart" : 1410, "hmmEnd" : 1666, "hmmLength" : 3942, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 3297, "envelopeEnd" : 3557, "location-fragments" : [ { "start" : 3301, "end" : 3557, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1111, "end" : 1641, "hmmStart" : 221, "hmmEnd" : 738, "hmmLength" : 3942, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1070, "envelopeEnd" : 1642, "location-fragments" : [ { "start" : 1111, "end" : 1641, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "", "score" : 2705.6, "model-ac" : "PTHR31516" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 235, "end" : 276, "location-fragments" : [ { "start" : 235, "end" : 276, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1334, "end" : 1360, "location-fragments" : [ { "start" : 1334, "end" : 1360, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 3159, "end" : 3236, "location-fragments" : [ { "start" : 3159, "end" : 3236, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1712, "end" : 1891, "location-fragments" : [ { "start" : 1712, "end" : 1891, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2057, "end" : 3557, "location-fragments" : [ { "start" : 2057, "end" : 3557, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1252, "end" : 1380, "location-fragments" : [ { "start" : 1252, "end" : 1380, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 409, "end" : 454, "location-fragments" : [ { "start" : 409, "end" : 454, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1586, "end" : 1891, "location-fragments" : [ { "start" : 1586, "end" : 1891, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 150, "end" : 388, "location-fragments" : [ { "start" : 150, "end" : 388, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2533, "end" : 2633, "location-fragments" : [ { "start" : 2533, "end" : 2633, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR31516:SF16", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1641, "end" : 2029, "hmmStart" : 1432, "hmmEnd" : 1802, "hmmLength" : 3942, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1639, "envelopeEnd" : 2035, "location-fragments" : [ { "start" : 1641, "end" : 2029, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2289, "end" : 2521, "hmmStart" : 1810, "hmmEnd" : 2042, "hmmLength" : 3942, "hmmBounds" : "COMPLETE", "envelopeStart" : 2289, "envelopeEnd" : 2521, "location-fragments" : [ { "start" : 2289, "end" : 2521, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1111, "end" : 1641, "hmmStart" : 221, "hmmEnd" : 738, "hmmLength" : 3942, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1070, "envelopeEnd" : 1642, "location-fragments" : [ { "start" : 1111, "end" : 1641, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "", "score" : 2705.6, "model-ac" : "PTHR31516:SF16" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1997, "end" : 2021, "location-fragments" : [ { "start" : 1997, "end" : 2021, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1273, "end" : 1292, "location-fragments" : [ { "start" : 1273, "end" : 1292, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 3509, "end" : 3557, "location-fragments" : [ { "start" : 3509, "end" : 3557, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1293, "end" : 1314, "location-fragments" : [ { "start" : 1293, "end" : 1314, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2642, "end" : 2694, "location-fragments" : [ { "start" : 2642, "end" : 2694, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1143, "end" : 1235, "location-fragments" : [ { "start" : 1143, "end" : 1235, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR31516:SF16", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 3062, "end" : 3331, "hmmStart" : 1408, "hmmEnd" : 1672, "hmmLength" : 3942, "hmmBounds" : "COMPLETE", "envelopeStart" : 3062, "envelopeEnd" : 3331, "location-fragments" : [ { "start" : 3062, "end" : 3331, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2001, "end" : 2340, "hmmStart" : 1717, "hmmEnd" : 2006, "hmmLength" : 3942, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1998, "envelopeEnd" : 2341, "location-fragments" : [ { "start" : 2001, "end" : 2340, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3301, "end" : 3557, "hmmStart" : 1410, "hmmEnd" : 1666, "hmmLength" : 3942, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 3297, "envelopeEnd" : 3557, "location-fragments" : [ { "start" : 3301, "end" : 3557, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "", "score" : 2705.6, "model-ac" : "PTHR31516:SF16" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2798, "end" : 2812, "location-fragments" : [ { "start" : 2798, "end" : 2812, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 368, "end" : 388, "location-fragments" : [ { "start" : 368, "end" : 388, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 195, "end" : 225, "location-fragments" : [ { "start" : 195, "end" : 225, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2735, "end" : 2781, "location-fragments" : [ { "start" : 2735, "end" : 2781, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 63, "location-fragments" : [ { "start" : 12, "end" : 63, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2110, "end" : 2376, "location-fragments" : [ { "start" : 2110, "end" : 2376, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR31516:SF16", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2855, "end" : 3139, "hmmStart" : 1413, "hmmEnd" : 1688, "hmmLength" : 3942, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 2855, "envelopeEnd" : 3143, "location-fragments" : [ { "start" : 2855, "end" : 3139, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "", "score" : 2705.6, "model-ac" : "PTHR31516:SF16" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 3300, "end" : 3500, "location-fragments" : [ { "start" : 3300, "end" : 3500, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1252, "end" : 1268, "location-fragments" : [ { "start" : 1252, "end" : 1268, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910020.1 PREDICTED: titin-like, partial [Bemisia tabaci]", "id" : "XP_018910020.1" } ] },{ "sequence" : "MPAIINNKGPYIAVIEEGTRTVKFVLFSAETQEEVVSYSVDVPGESPQEGWAEQDPNTLLSAVHLCIEETMPQLATIGASSKDIVALGITNQRETTIVWDSITGEPLYNAILWSDMRADVTVDEVLAKFPDNNKDYLKPLSGLPVSPYFSALKLKWLIDNVPSVRKAIREHRCLFGTVDSWLIWNLTGGKDGGLHITDVTNASRTMLMNIDSLQWDPLLCKHFHIPMEILPEIRSSSEIYGLVKGHMLDGVPISGILGNQQAALVGQRCFKEGQAKNTYRSGCFLLYNTGNNRVHSSQGLVTTVAFQHGRDKRPVYALEGSVAVAGTALKWLRDNLNMMKDNEEAEDLAEAVKTTGDVYFVPAFAGLYAPYWRKDARGILCGLTQFTTKGHIIRAALEAVCYQTRDILEAMHRDCGFPLSTLHVDGQMTTNRLLMQLQADISGIPVQRNNKKDITALGVAYMAASAAGIDVWDLENLSANSGSDASLEDTFLPSISHEERNLRYTKWKMAVHRSLGWAMPKKSDVMTGNDSDSHTNVCKSSALAEKYCVNSDNVRSSEINLFNKPPSYGNEENCLTANHEFSVKKINNYDKENYSNVPFKMADKPSFGEKHSHAKDISNIEILPANRVFSQNFEPDENQNTLKETSLDSNILRETCLDQNILIGNSVSNNLLIEVVDKKDINENGITEELFEDIFENKENLLTDILEKAKITNFEGSLAQVDSNLEKPHIFPAKYILAAHIKSCHNDDIFVLGHHSR", "md5" : "45882800e82ff7f50e460e01aa3ceb68", "matches" : [ { "signature" : { "accession" : "G3DSA:3.30.420.40", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 268, "end" : 519, "hmmStart" : 2, "hmmEnd" : 244, "hmmLength" : 247, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-81, "score" : 274.8, "envelopeStart" : 268, "envelopeEnd" : 519, "postProcessed" : true, "location-fragments" : [ { "start" : 268, "end" : 519, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-81, "score" : 275.5, "model-ac" : "3ezwD02" }, { "signature" : { "accession" : "PTHR10196:SF40", "name" : "FI03690P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 532, "hmmStart" : 8, "hmmEnd" : 530, "hmmLength" : 558, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 557, "location-fragments" : [ { "start" : 10, "end" : 532, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-255, "familyName" : "FI03690P", "score" : 850.8, "model-ac" : "PTHR10196:SF40" }, { "signature" : { "accession" : "PTHR10196", "name" : "SUGAR KINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 532, "hmmStart" : 8, "hmmEnd" : 530, "hmmLength" : 558, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 557, "location-fragments" : [ { "start" : 10, "end" : 532, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-255, "familyName" : "FI03690P", "score" : 850.8, "model-ac" : "PTHR10196" }, { "signature" : { "accession" : "SSF53067", "name" : "Actin-like ATPase domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR043129", "name" : "ATPase_NBD", "description" : "ATPase, nucleotide binding domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 11, "end" : 269, "hmmLength" : 252, "location-fragments" : [ { "start" : 11, "end" : 269, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.78E-70, "model-ac" : "0049108" }, { "signature" : { "accession" : "PF00370", "name" : "FGGY_N", "description" : "FGGY family of carbohydrate kinases, N-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018484", "name" : "Carb_kinase_FGGY_N", "description" : "Carbohydrate kinase, FGGY, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 11, "end" : 266, "hmmStart" : 1, "hmmEnd" : 245, "hmmLength" : 245, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-66, "score" : 223.8, "envelopeStart" : 11, "envelopeEnd" : 266, "postProcessed" : true, "location-fragments" : [ { "start" : 11, "end" : 266, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-66, "score" : 224.8, "model-ac" : "PF00370" }, { "signature" : { "accession" : "PF02782", "name" : "FGGY_C", "description" : "FGGY family of carbohydrate kinases, C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018485", "name" : "Carb_kinase_FGGY_C", "description" : "Carbohydrate kinase, FGGY, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 275, "end" : 466, "hmmStart" : 1, "hmmEnd" : 197, "hmmLength" : 198, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.1E-60, "score" : 204.8, "envelopeStart" : 275, "envelopeEnd" : 467, "postProcessed" : true, "location-fragments" : [ { "start" : 275, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-61, "score" : 205.7, "model-ac" : "PF02782" }, { "signature" : { "accession" : "SSF53067", "name" : "Actin-like ATPase domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR043129", "name" : "ATPase_NBD", "description" : "ATPase, nucleotide binding domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 269, "end" : 518, "hmmLength" : 246, "location-fragments" : [ { "start" : 269, "end" : 518, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.01E-69, "model-ac" : "0035709" }, { "signature" : { "accession" : "PS00445", "name" : "FGGY_KINASES_2", "description" : "FGGY family of carbohydrate kinases signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018483", "name" : "Carb_kinase_FGGY_CS", "description" : "Carbohydrate kinase, FGGY, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Glycerol degradation I", "databaseName" : "MetaCyc", "id" : "PWY-4261" }, { "name" : "Glycerolipid metabolism", "databaseName" : "KEGG", "id" : "00561+2.7.1.30" } ] } }, "locations" : [ { "start" : 378, "end" : 398, "level" : "STRONG", "cigarAlignment" : "1M1I4M7I8M", "alignment" : "GiLCGLtqfttkgHIIRAALE", "location-fragments" : [ { "start" : 378, "end" : 398, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00445" }, { "signature" : { "accession" : "G3DSA:3.30.420.40", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 267, "hmmStart" : 9, "hmmEnd" : 267, "hmmLength" : 268, "hmmBounds" : "COMPLETE", "evalue" : 9.7E-91, "score" : 305.7, "envelopeStart" : 5, "envelopeEnd" : 267, "postProcessed" : true, "location-fragments" : [ { "start" : 5, "end" : 267, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-91, "score" : 308.7, "model-ac" : "3wxlA01" }, { "signature" : { "accession" : "TIGR01311", "name" : "TIGR01311", "description" : "glycerol_kin: glycerol kinase", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR005999", "name" : "Glycerol_kin", "description" : "Glycerol kinase", "type" : "FAMILY", "goXRefs" : [ { "name" : "glycerol-3-phosphate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006072" }, { "name" : "glycerol kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004370" } ], "pathwayXRefs" : [ { "name" : "Glycerol degradation I", "databaseName" : "MetaCyc", "id" : "PWY-4261" }, { "name" : "Triglyceride biosynthesis", "databaseName" : "Reactome", "id" : "R-HSA-75109" }, { "name" : "Glycerolipid metabolism", "databaseName" : "KEGG", "id" : "00561+2.7.1.30" } ] } }, "locations" : [ { "start" : 10, "end" : 517, "hmmStart" : 1, "hmmEnd" : 496, "hmmLength" : 496, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-199, "score" : 660.7, "envelopeStart" : 10, "envelopeEnd" : 517, "postProcessed" : false, "location-fragments" : [ { "start" : 10, "end" : 517, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-199, "score" : 661.0, "model-ac" : "TIGR01311" }, { "signature" : { "accession" : "PS00933", "name" : "FGGY_KINASES_1", "description" : "FGGY family of carbohydrate kinases signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018483", "name" : "Carb_kinase_FGGY_CS", "description" : "Carbohydrate kinase, FGGY, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Glycerol degradation I", "databaseName" : "MetaCyc", "id" : "PWY-4261" }, { "name" : "Glycerolipid metabolism", "databaseName" : "KEGG", "id" : "00561+2.7.1.30" } ] } }, "locations" : [ { "start" : 148, "end" : 160, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I8M", "alignment" : "YfSalKLKWLIDN", "location-fragments" : [ { "start" : 148, "end" : 160, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00933" } ], "xref" : [ { "name" : "XP_018909613.1 PREDICTED: glycerol kinase-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909613.1" } ] },{ "sequence" : "MENQANPPISDQEKLRIVSDFILHSPPGEFNEVFNDVRGLLNNDVLLKEGACGAFAQYNKDQFTPVKIENSDSSVLITEHNDLGNGRFYDPRSKQSFRYDHLRKEASDYDSYELDPSTESWRAAIEAEFDNYTVSHYKHGFCSVFSKKQGPSITLVACIEDHQFQPKNYWNGRWRSQWTITISSGTAELKGVLKVQVHYYEDGNVQLVSSKEVKESVPISSEEQTAKELIKLVEDAENEYQTAISENYQTMSDTTFKALRRQLPVRRTKVDWNKIISLQYLTVSLKNHNHNE", "md5" : "fef9a9bb1c5387ade8d7d31dbe868174", "matches" : [ { "signature" : { "accession" : "G3DSA:2.40.160.80", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042276", "name" : "CapZ_alpha/beta_2", "description" : "F-actin-capping protein subunit alpha/beta, domain 2", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "COPI-independent Golgi-to-ER retrograde traffic", "databaseName" : "Reactome", "id" : "R-HSA-6811436" }, { "name" : "COPI-mediated anterograde transport", "databaseName" : "Reactome", "id" : "R-HSA-6807878" }, { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" }, { "name" : "HSP90 chaperone cycle for steroid hormone receptors (SHR)", "databaseName" : "Reactome", "id" : "R-HSA-3371497" } ] } }, "locations" : [ { "start" : 115, "end" : 259, "hmmStart" : 4, "hmmEnd" : 145, "hmmLength" : 145, "hmmBounds" : "COMPLETE", "evalue" : 5.2E-58, "score" : 196.9, "envelopeStart" : 115, "envelopeEnd" : 259, "postProcessed" : true, "location-fragments" : [ { "start" : 115, "end" : 259, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-58, "score" : 197.6, "model-ac" : "5afuK02" }, { "signature" : { "accession" : "PR00191", "name" : "FACTINCAPA", "description" : "F-actin capping protein alpha subunit signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002189", "name" : "CapZ_alpha", "description" : "F-actin-capping protein subunit alpha", "type" : "FAMILY", "goXRefs" : [ { "name" : "F-actin capping protein complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0008290" }, { "name" : "barbed-end actin filament capping", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0051016" } ], "pathwayXRefs" : [ { "name" : "COPI-independent Golgi-to-ER retrograde traffic", "databaseName" : "Reactome", "id" : "R-HSA-6811436" }, { "name" : "COPI-mediated anterograde transport", "databaseName" : "Reactome", "id" : "R-HSA-6807878" }, { "name" : "HSP90 chaperone cycle for steroid hormone receptors (SHR)", "databaseName" : "Reactome", "id" : "R-HSA-3371497" }, { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 164, "end" : 178, "pvalue" : 2.93E-9, "score" : 70.67, "motifNumber" : 1, "location-fragments" : [ { "start" : 164, "end" : 178, "dc-status" : "CONTINUOUS" } ] }, { "start" : 196, "end" : 209, "pvalue" : 8.86E-9, "score" : 86.43, "motifNumber" : 2, "location-fragments" : [ { "start" : 196, "end" : 209, "dc-status" : "CONTINUOUS" } ] }, { "start" : 253, "end" : 272, "pvalue" : 2.32E-12, "score" : 80.0, "motifNumber" : 3, "location-fragments" : [ { "start" : 253, "end" : 272, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-22, "graphscan" : "III", "model-ac" : "PR00191" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 219, "end" : 246, "location-fragments" : [ { "start" : 219, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR10653", "name" : "F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR002189", "name" : "CapZ_alpha", "description" : "F-actin-capping protein subunit alpha", "type" : "FAMILY", "goXRefs" : [ { "name" : "F-actin capping protein complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0008290" }, { "name" : "barbed-end actin filament capping", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0051016" } ], "pathwayXRefs" : [ { "name" : "COPI-independent Golgi-to-ER retrograde traffic", "databaseName" : "Reactome", "id" : "R-HSA-6811436" }, { "name" : "COPI-mediated anterograde transport", "databaseName" : "Reactome", "id" : "R-HSA-6807878" }, { "name" : "HSP90 chaperone cycle for steroid hormone receptors (SHR)", "databaseName" : "Reactome", "id" : "R-HSA-3371497" }, { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 7, "end" : 279, "hmmStart" : 6, "hmmEnd" : 278, "hmmLength" : 315, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 291, "location-fragments" : [ { "start" : 7, "end" : 279, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-133, "familyName" : "CAPPING PROTEIN (ACTIN FILAMENT) MUSCLE Z-LINE, ALPHA 1B", "score" : 447.5, "model-ac" : "PTHR10653" }, { "signature" : { "accession" : "PF01267", "name" : "F-actin_cap_A", "description" : "F-actin capping protein alpha subunit", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002189", "name" : "CapZ_alpha", "description" : "F-actin-capping protein subunit alpha", "type" : "FAMILY", "goXRefs" : [ { "name" : "F-actin capping protein complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0008290" }, { "name" : "barbed-end actin filament capping", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0051016" } ], "pathwayXRefs" : [ { "name" : "COPI-independent Golgi-to-ER retrograde traffic", "databaseName" : "Reactome", "id" : "R-HSA-6811436" }, { "name" : "COPI-mediated anterograde transport", "databaseName" : "Reactome", "id" : "R-HSA-6807878" }, { "name" : "HSP90 chaperone cycle for steroid hormone receptors (SHR)", "databaseName" : "Reactome", "id" : "R-HSA-3371497" }, { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 18, "end" : 278, "hmmStart" : 1, "hmmEnd" : 260, "hmmLength" : 267, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 7.9E-100, "score" : 333.7, "envelopeStart" : 18, "envelopeEnd" : 283, "postProcessed" : true, "location-fragments" : [ { "start" : 18, "end" : 278, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-100, "score" : 333.9, "model-ac" : "PF01267" }, { "signature" : { "accession" : "SSF90096", "name" : "Subunits of heterodimeric actin filament capping protein Capz", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR037282", "name" : "CapZ_alpha/beta", "description" : "F-actin-capping protein subunit alpha/beta", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" }, { "name" : "COPI-mediated anterograde transport", "databaseName" : "Reactome", "id" : "R-HSA-6807878" }, { "name" : "COPI-independent Golgi-to-ER retrograde traffic", "databaseName" : "Reactome", "id" : "R-HSA-6811436" }, { "name" : "HSP90 chaperone cycle for steroid hormone receptors (SHR)", "databaseName" : "Reactome", "id" : "R-HSA-3371497" } ] } }, "locations" : [ { "start" : 9, "end" : 279, "hmmLength" : 275, "location-fragments" : [ { "start" : 9, "end" : 279, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.83E-106, "model-ac" : "0039297" }, { "signature" : { "accession" : "PS00748", "name" : "F_ACTIN_CAPPING_A_1", "description" : "F-actin capping protein alpha subunit signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017865", "name" : "F-actin_cap_asu_CS", "description" : "F-actin capping protein, alpha subunit, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" }, { "name" : "HSP90 chaperone cycle for steroid hormone receptors (SHR)", "databaseName" : "Reactome", "id" : "R-HSA-3371497" }, { "name" : "COPI-independent Golgi-to-ER retrograde traffic", "databaseName" : "Reactome", "id" : "R-HSA-6811436" }, { "name" : "COPI-mediated anterograde transport", "databaseName" : "Reactome", "id" : "R-HSA-6807878" } ] } }, "locations" : [ { "start" : 197, "end" : 205, "level" : "STRONG", "cigarAlignment" : "9M", "alignment" : "VHYYEDGNV", "location-fragments" : [ { "start" : 197, "end" : 205, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00748" }, { "signature" : { "accession" : "PTHR10653:SF14", "name" : "CAPPING PROTEIN (ACTIN FILAMENT) MUSCLE Z-LINE, ALPHA 1B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 279, "hmmStart" : 6, "hmmEnd" : 278, "hmmLength" : 315, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 291, "location-fragments" : [ { "start" : 7, "end" : 279, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-133, "familyName" : "CAPPING PROTEIN (ACTIN FILAMENT) MUSCLE Z-LINE, ALPHA 1B", "score" : 447.5, "model-ac" : "PTHR10653:SF14" }, { "signature" : { "accession" : "G3DSA:1.20.1290.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042489", "name" : "CapZ_alpha_1", "description" : "F-actin capping protein, alpha subunit, domain 1", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "COPI-mediated anterograde transport", "databaseName" : "Reactome", "id" : "R-HSA-6807878" }, { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" }, { "name" : "HSP90 chaperone cycle for steroid hormone receptors (SHR)", "databaseName" : "Reactome", "id" : "R-HSA-3371497" }, { "name" : "COPI-independent Golgi-to-ER retrograde traffic", "databaseName" : "Reactome", "id" : "R-HSA-6811436" } ] } }, "locations" : [ { "start" : 3, "end" : 114, "hmmStart" : 7, "hmmEnd" : 110, "hmmLength" : 113, "hmmBounds" : "COMPLETE", "evalue" : 5.7E-45, "score" : 153.9, "envelopeStart" : 3, "envelopeEnd" : 114, "postProcessed" : true, "location-fragments" : [ { "start" : 3, "end" : 114, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-45, "score" : 155.3, "model-ac" : "3aa0A01" } ], "xref" : [ { "name" : "XP_018909572.1 PREDICTED: F-actin-capping protein subunit alpha [Bemisia tabaci]", "id" : "XP_018909572.1" } ] },{ "sequence" : "MSSYRSNYSSYSSSYLGSRFNTVTRTYTSSGSSRSSFSSGFTPTSSSVLSLRDKYNSLSRNSTSSVGTSRTERSSSQYDSKSGSDSYSRSYSTYKPYSSTSTESSTRASSYTPYKSYTAGSSDSSSKSTYTPWSKSYRSSVPESTYSYRSRYSSKPDAEASTEKSSTYRSSYSKPEPESNSYTSSSRDVDSRSSYSRFKSDPEPTPRKDEPEVSSYSKPSSEYKPSSYSSKNETDTSSAKDSLSVYSRYGHYGTRKSPAPSASEESKDEVKVSVTTRYTSPTPPSNSAYLRNRRAELESIYQCEIVRKSRVSKTDCQTQTDENDIYAAMKSESSEGENSEPAEPPLAASRSPVHISKSDVDVNQNIKESESFNYVRPTDITSKTVITVDSSLDPARGVHPSTEESLFAPSTFQYTSSYPNLKNSSTVSSHPNSLSVSTAILNLPNKSPTFSESDVSEKQSSPDGSLSAGKASFEKFPSPEKISEDSKNSAASKEGYKSSSSPSFGLEKAVPNQKCSLKSSSPARSPSPNSRLSRSRSPTPSYSFTISPRHHQTRSKDSSASQTNEFSVAQPEILDKSSSYHLNIPSAFQLNLEKKMSDPSRSLSRSPSPSPARGRTPENINYSSLNDPNQPSAGRLLSLAKSTSFVSKKAEYIEPVVSVPFKSTHRFSEQFSDSDISRSETSVPKIRLATYPSDSEEPYRKDTKGCSSERVPEKPIKTSESDSLSFNGPPSSTSQSPFPQEECASKPPVHPASPIVGIRVSSKERMESLRYAMMRSETPAMAFKNKSFESSSEDISDLTFDFSGKHYVINEFTENHIPNARKPLESINNEKPKEGDSFSQTEGMGQAQSQKIRKFDSGERDWWARDDTQSESFRHSSRHDSTEPPNDSSKEFSYHGAQSESMSPDGTKYPSQHHIRKFDSGERDWWAQNEPGRDAPSESPQNDIQHDSSNDSSGEFSNHEAQSRSVSPDYPKQSSQHHIRKFDSGEREWWLEDERNSGSVEGALDEDEAVENEEEEVDFWAELAAENEKHELELQHAYQLRNMDVDSSSWWIEEKTKDGDRDNQPSSGISRRTPEEDEANADEYYDAEADNSAHERNEEIYSYSIRKFDSGETPWFAEQENDDQTDKRPGSDSCQDQNQVESGIWSMETFDSTSNRPSEQFLIRTGSGHTLWYAADKSEPPVELANNERFFKIGEGERMCWIDDNTLSHTYSGSATEQPWFPDKTLSEDQVEGPYKIKRIESGEKPWWLDEDEKTDAGFDDTLCSHFRGSESRSENNVTRADLSSKASDGEEDLEPFSRVVRRVPNPTLFISELTNIDQLLGDELSFSNQCLEPTFAKIKDDGPASEDEDEIEEVSADQVKIHDNTPQTYIIEPFKGILKLDDAALQLYKDGDYSSYLDLDATISEQQEEFEGFQSNRKNSIVLRTQLSVRVHTIIEKLLNSEGSELRRALFCLKQIFQEDKDLVHEFVQNDGLSCLIKVGSDANQNYQNYILRALGQVMLYVDGMNGVIEHNETIQWLYCLVSSKFRLVVKTALKLLLVFVEYVESNCLLLIQAIHTVDKSRGSLPWSNIMKLLNEYDVTDTELLIYAMTLINKTLNRVPDLDMYYDQVDEIEKQGIQEIVQRYMSRPGTDLDFLHQLQSYEAVLNHEDGGDKTIPLKQLDDNVRTTRFSNASMISDIERRRSRRHSTGTVPLSLSVSPYNKANEDYHLKQAAEDGVGVTPALRRRLERGDRQKLLIPQEELCKSSTENYSSDDGGMKNGLKSELSNGDLKYYNGETESCLPRENTVKDLTQRLATLNSPNEESPTKLTPPPRVGEMKGIISKAIEGLAKSQSKSELKSPTNETPPMRIPEVKKSETELHWEELLASTTRALQLCDLDFTDLGSDDEKNILAPTSVANGIPPPPPPCVLPPPAPAAPLQSLTKTKKTVKLFWKEVCEDPIVMAKMNSSLIWDELTPVPVDTQKLEHLFESRTKDLITKKQHELNKNKEIIVLDPKRSNAINIGMTKLPPPRAIKTAILKMDATVMNREGIEKLLTMLPSEEERTKIQEAQTANPELPLGSAEQFLLTLASIIELPARLKLWAFKLDYENSEKEIAEPLMDLKQGMELLKANKTFRAILATLLSIGIFLNGNEVKGFQIEYLAKVPEVKDTVHKHSLLHHLCHMVMSKFPQSTDLYSEIGAVTRASKVDFDELALSIHRMEQECKASFDHLKVIVKHDGSNAMKGKMSDFLADCAERIIVLCKVHRRVINRYHKFCLWLGIPLHRVCLTKPNELCRIISEFALEYRTTRERVLQQLEKKANHRERNKTRGKMITEIGKVDTKEDRADAELRQLLGNESIDRPNSASPLHGSLPWRRQKKNSNGKGSPDQRKNGHLTDGDDELLETLVKTATKIPATRSAPRERKRIRNADRKSFRQRTLRNGLSEEDKKYLASYIESF", "md5" : "75dcf0cc19ac0e637607ba6ea859ce1d", "matches" : [ { "signature" : { "accession" : "PS51232", "name" : "GBD_FH3", "description" : "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR014768", "name" : "GBD/FH3_dom", "description" : "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1373, "end" : 1729, "score" : 20.381, "alignment" : "EPFKGILKLDDAALQLYKDGDYSS---YLDLDATISEQQEEFEGFQSNR--------KNSIVLRTQLSVRVHTIIEKLLNSEGSELRRALFCLKqifqedKDLVHEFVQNDGLSCLIKVGSDANQN---------YQNYILRALGQVMLYVDGMNGVIEHNETIQWLYCLVSSKFRLVVKTALKLLLVFVEY-VESNCLLLIQAIHTVDKS-RGSLPWSNIMKLLNEYDVTDTELLIYAMTLINKTLNRVPDLDMYYDQVDEIEKQGIQEIVQRYMSrPGTDLDFLHQLQSYeAVLNHEDGGDKTIPLKQLDD-NVRTTRFSNASMISDIERRRSRRHSTGTVPLSLSVSPYNKANEDYHLKQAAEDGVGVTPALRRRLE", "location-fragments" : [ { "start" : 1373, "end" : 1729, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51232" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 439, "end" : 467, "location-fragments" : [ { "start" : 439, "end" : 467, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 974, "end" : 1002, "location-fragments" : [ { "start" : 974, "end" : 1002, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF18382", "name" : "Formin_GBD_N", "description" : "Formin N-terminal GTPase-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR041387", "name" : "FHOD1_GBD_N", "description" : "FHOD1, N-terminal GTPase-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1378, "end" : 1427, "hmmStart" : 50, "hmmEnd" : 99, "hmmLength" : 99, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.3E-16, "score" : 59.0, "envelopeStart" : 1360, "envelopeEnd" : 1427, "postProcessed" : true, "location-fragments" : [ { "start" : 1378, "end" : 1427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-16, "score" : 60.8, "model-ac" : "PF18382" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 887, "end" : 908, "location-fragments" : [ { "start" : 887, "end" : 908, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2397, "end" : 2412, "location-fragments" : [ { "start" : 2397, "end" : 2412, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 588, "end" : 635, "location-fragments" : [ { "start" : 588, "end" : 635, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00498", "name" : "it6_source", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR015425", "name" : "FH2_Formin", "description" : "Formin, FH2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1918, "end" : 2364, "hmmStart" : 1, "hmmEnd" : 499, "hmmLength" : 499, "hmmBounds" : "COMPLETE", "evalue" : 6.6E-59, "score" : 211.7, "location-fragments" : [ { "start" : 1918, "end" : 2364, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-59, "score" : 211.7, "model-ac" : "SM00498" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 492, "end" : 549, "location-fragments" : [ { "start" : 492, "end" : 549, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 273, "end" : 289, "location-fragments" : [ { "start" : 273, "end" : 289, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1048, "end" : 1078, "location-fragments" : [ { "start" : 1048, "end" : 1078, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 593, "end" : 635, "location-fragments" : [ { "start" : 593, "end" : 635, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 216, "end" : 244, "location-fragments" : [ { "start" : 216, "end" : 244, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 192, "end" : 215, "location-fragments" : [ { "start" : 192, "end" : 215, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 934, "end" : 973, "location-fragments" : [ { "start" : 934, "end" : 973, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 910, "end" : 929, "location-fragments" : [ { "start" : 910, "end" : 929, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 318, "end" : 335, "location-fragments" : [ { "start" : 318, "end" : 335, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 813, "end" : 1015, "location-fragments" : [ { "start" : 813, "end" : 1015, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 694, "end" : 717, "location-fragments" : [ { "start" : 694, "end" : 717, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 144, "end" : 191, "location-fragments" : [ { "start" : 144, "end" : 191, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 477, "end" : 491, "location-fragments" : [ { "start" : 477, "end" : 491, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 718, "end" : 741, "location-fragments" : [ { "start" : 718, "end" : 741, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2361, "end" : 2386, "location-fragments" : [ { "start" : 2361, "end" : 2386, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 674, "end" : 688, "location-fragments" : [ { "start" : 674, "end" : 688, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 52, "end" : 109, "location-fragments" : [ { "start" : 52, "end" : 109, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1087, "end" : 1105, "location-fragments" : [ { "start" : 1087, "end" : 1105, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR45920", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1783, "end" : 2434, "hmmStart" : 513, "hmmEnd" : 1161, "hmmLength" : 1165, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1772, "envelopeEnd" : 2437, "location-fragments" : [ { "start" : 1783, "end" : 2434, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1371, "end" : 1706, "hmmStart" : 37, "hmmEnd" : 349, "hmmLength" : 1165, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1290, "envelopeEnd" : 1768, "location-fragments" : [ { "start" : 1371, "end" : 1706, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "FAMILY NOT NAMED", "score" : 1388.4, "model-ac" : "PTHR45920" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 144, "end" : 291, "location-fragments" : [ { "start" : 144, "end" : 291, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51444", "name" : "FH2", "description" : "Formin homology-2 (FH2) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR015425", "name" : "FH2_Formin", "description" : "Formin, FH2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1918, "end" : 2311, "score" : 43.954, "alignment" : "PLQSLTKTKKTVKLFWKEVcEDPIVMAKMNSSLIWdELTPVPVDTQKLEHLFESR----TKDLITKKQHELNKNKEIIVLDPKRSNAINIGMTKL-PPPRAIKTAILKMDATVMNREGIEKLLTMLPSEEERTKIQEAQTANPeLPLGSAEQFLLTLASIIELPARLKLWAFKLDYENSEKEIAEPLMDLKQGMELLKANKTFRAILATLLSIGIFLNGN----EVKGFQIEYLAKVPEVKDTVHKHSLLHHLCHMVMSKFPQSTDLYSEIGAVTRASKVDFDELALSIHRMEQECKASFDHLKVIVKH--DGSNAMKGKMSDFLADCAERIIVLCKVHRRVINRYHKFCLWLGIPLHrvcLTKPNELCRIISEFALEYRTTRERVLQQLEKKANHRERNKTRGK", "location-fragments" : [ { "start" : 1918, "end" : 2311, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51444" }, { "signature" : { "accession" : "PF02181", "name" : "FH2", "description" : "Formin Homology 2 Domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR015425", "name" : "FH2_Formin", "description" : "Formin, FH2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1921, "end" : 2285, "hmmStart" : 4, "hmmEnd" : 371, "hmmLength" : 372, "hmmBounds" : "INCOMPLETE", "evalue" : 4.5E-83, "score" : 279.4, "envelopeStart" : 1918, "envelopeEnd" : 2286, "postProcessed" : true, "location-fragments" : [ { "start" : 1921, "end" : 2285, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-83, "score" : 279.4, "model-ac" : "PF02181" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 314, "end" : 359, "location-fragments" : [ { "start" : 314, "end" : 359, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2297, "end" : 2412, "location-fragments" : [ { "start" : 2297, "end" : 2412, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2297, "end" : 2331, "location-fragments" : [ { "start" : 2297, "end" : 2331, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 439, "end" : 574, "location-fragments" : [ { "start" : 439, "end" : 574, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 557, "end" : 574, "location-fragments" : [ { "start" : 557, "end" : 574, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF101447", "name" : "Formin homology 2 domain (FH2 domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 1902, "end" : 2305, "hmmLength" : 411, "location-fragments" : [ { "start" : 1902, "end" : 2305, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-84, "model-ac" : "0044554" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 853, "end" : 886, "location-fragments" : [ { "start" : 853, "end" : 886, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.20.58.2220", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042201", "name" : "FH2_Formin_sf", "description" : "Formin, FH2 domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1983, "end" : 2315, "hmmStart" : 4, "hmmEnd" : 327, "hmmLength" : 340, "hmmBounds" : "COMPLETE", "evalue" : 5.4E-80, "score" : 270.9, "envelopeStart" : 1983, "envelopeEnd" : 2315, "postProcessed" : true, "location-fragments" : [ { "start" : 1983, "end" : 2315, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-80, "score" : 271.6, "model-ac" : "1v9dB00" }, { "signature" : { "accession" : "SSF48371", "name" : "ARM repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016024", "name" : "ARM-type_fold", "description" : "Armadillo-type fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1436, "end" : 1651, "hmmLength" : 343, "location-fragments" : [ { "start" : 1436, "end" : 1651, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.84E-27, "model-ac" : "0052018" }, { "signature" : { "accession" : "G3DSA:1.25.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011989", "name" : "ARM-like", "description" : "Armadillo-like helical", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1351, "end" : 1651, "hmmStart" : 62, "hmmEnd" : 339, "hmmLength" : 339, "hmmBounds" : "COMPLETE", "evalue" : 8.7E-132, "score" : 440.9, "envelopeStart" : 1351, "envelopeEnd" : 1651, "postProcessed" : true, "location-fragments" : [ { "start" : 1351, "end" : 1651, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.7E-132, "score" : 440.9, "model-ac" : "3dadA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 668, "end" : 761, "location-fragments" : [ { "start" : 668, "end" : 761, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1043, "end" : 1139, "location-fragments" : [ { "start" : 1043, "end" : 1139, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909666.1 PREDICTED: uncharacterized protein LOC109038874 isoform X2 [Bemisia tabaci]", "id" : "XP_018909666.1" } ] },{ "sequence" : "MSDSSKAKIYWGGKTVHQNSDTYWNKYPLKPGEELCETDSGSFYNPLHSDEERWHTKRSGESSDEERQKKKKKRKHRSDEPSKRSRHSSKESSRRSRHSSNELSKRSKHTSAERSKRRRLNSEEHKKRIRHSSEDRSKRGKESSEERGRRSKYSSNDERPKKKERRKHEDKHEDKPKQNRSHRQEKPKKAKEEPKTIDTPKEVITEDQKKTVDLLTSKTGGAYIPPAKLRMMQASITDKASAAYQRIAWEALKKSLHGLINKASPQNICIIAREILRENIIRGRGLLCRSIIQAQAASPTFTNVFAALVAIINSKFPNIGELLLKRCIIRFKQGFRRNDKPTCLAAAIFIAHLVNQCVAHEIAALELLTLLLETPTNDSVEVAIAFLKECGQKLSIVCKRGLDDIFDLLRNILHEGSLEKRVQYMIEVMFQVRKDGFKDHPTIPEELDLVEEEDQFTHVLSLTEDKLEGQEILNVFKFDPEYEENEKKYENLKKELFGSDDESGEESGSEDESGSDDSDDSEAAEEKKQTIIDNTETNLVALRRTIYLTINSSLDFEECAHKLLKMELKPGQEIEMCNMFLDCCAEQRTYEKFYGLLAERFCRINQIYVAPFEKIFVDSYAIVHRFTTNKLRNVAKFFAHLLFTDAISWNVLSTIHLNEEETSSSSRIFIKILFQELSEFMSLAKLNDRIKDPTMHLAFEGLFPRDNPKNTRFAINFFTSIGLGGLTNELREHLKAQPKQSNVNKIMEALSASSSSSSSSTSDCDSDSSSSSSSSD", "md5" : "4463ce90a6ee0490f2ead9da2df0b47f", "matches" : [ { "signature" : { "accession" : "SSF48371", "name" : "ARM repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016024", "name" : "ARM-type_fold", "description" : "Armadillo-type fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 242, "end" : 485, "hmmLength" : 264, "location-fragments" : [ { "start" : 242, "end" : 485, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.17E-62, "model-ac" : "0047129" }, { "signature" : { "accession" : "SM00544", "name" : "ma3_7", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003891", "name" : "Initiation_fac_eIF4g_MI", "description" : "Initiation factor eIF-4 gamma, MA3", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 542, "end" : 648, "hmmStart" : 1, "hmmEnd" : 117, "hmmLength" : 117, "hmmBounds" : "COMPLETE", "evalue" : 5.9E-26, "score" : 102.2, "location-fragments" : [ { "start" : 542, "end" : 648, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-26, "score" : 102.2, "model-ac" : "SM00544" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 489, "end" : 530, "location-fragments" : [ { "start" : 489, "end" : 530, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51366", "name" : "MI", "description" : "MI domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR003891", "name" : "Initiation_fac_eIF4g_MI", "description" : "Initiation factor eIF-4 gamma, MA3", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 541, "end" : 657, "score" : 20.43, "alignment" : "ALRRTIYLTINSSL---DFEECAHKLLKMELKpGQEIEMCNMFLDCCAEQ-RTYEKFYGLLAERFCRINQIYVAPFEKIFVDSYAIVHRFTTN---KLRNVAKFFAHLLFTDAISWNVLSTIHL", "location-fragments" : [ { "start" : 541, "end" : 657, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51366" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 482, "end" : 502, "location-fragments" : [ { "start" : 482, "end" : 502, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "G3DSA:1.25.40.180", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR016021", "name" : "MIF4-like_sf", "description" : "MIF4G-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 206, "end" : 497, "hmmStart" : 4, "hmmEnd" : 290, "hmmLength" : 291, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-94, "score" : 318.2, "envelopeStart" : 206, "envelopeEnd" : 497, "postProcessed" : true, "location-fragments" : [ { "start" : 206, "end" : 497, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-94, "score" : 318.2, "model-ac" : "4c9bB00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 46, "end" : 68, "location-fragments" : [ { "start" : 46, "end" : 68, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 205, "location-fragments" : [ { "start" : 1, "end" : 205, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 94, "end" : 109, "location-fragments" : [ { "start" : 94, "end" : 109, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF02847", "name" : "MA3", "description" : "MA3 domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR003891", "name" : "Initiation_fac_eIF4g_MI", "description" : "Initiation factor eIF-4 gamma, MA3", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 542, "end" : 647, "hmmStart" : 1, "hmmEnd" : 112, "hmmLength" : 113, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.2E-23, "score" : 83.2, "envelopeStart" : 542, "envelopeEnd" : 648, "postProcessed" : true, "location-fragments" : [ { "start" : 542, "end" : 647, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-24, "score" : 84.3, "model-ac" : "PF02847" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 502, "end" : 520, "location-fragments" : [ { "start" : 502, "end" : 520, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR18034:SF3", "name" : "PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 64, "end" : 774, "hmmStart" : 4, "hmmEnd" : 720, "hmmLength" : 759, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 51, "envelopeEnd" : 776, "location-fragments" : [ { "start" : 64, "end" : 774, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG", "score" : 1020.0, "model-ac" : "PTHR18034:SF3" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 116, "end" : 205, "location-fragments" : [ { "start" : 116, "end" : 205, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR18034", "name" : "CELL CYCLE CONTROL PROTEIN CWF22-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 64, "end" : 774, "hmmStart" : 4, "hmmEnd" : 720, "hmmLength" : 759, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 51, "envelopeEnd" : 776, "location-fragments" : [ { "start" : 64, "end" : 774, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG", "score" : 1020.0, "model-ac" : "PTHR18034" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 741, "end" : 776, "location-fragments" : [ { "start" : 741, "end" : 776, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00543", "name" : "if4_15", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003890", "name" : "MIF4G-like_typ-3", "description" : "MIF4G-like, type 3", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" }, { "name" : "RNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003723" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 253, "end" : 436, "hmmStart" : 1, "hmmEnd" : 227, "hmmLength" : 227, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-38, "score" : 143.0, "location-fragments" : [ { "start" : 253, "end" : 436, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-38, "score" : 143.0, "model-ac" : "SM00543" } ], "xref" : [ { "name" : "XP_018910001.1 PREDICTED: pre-mRNA-splicing factor CWC22 homolog [Bemisia tabaci]", "id" : "XP_018910001.1" } ] },{ "sequence" : "MNFPRLNSKQPLELIKQGSMKAGTLARKFSRVASGVLRMNPEYPTFKELDAKLRKYSSAADKEAALQDVISTGSLLYYKEKNKSTPTQTGDLEYLSDDLISLVRGSHSEFTTPETSKRKAIRGRSSCNKHCFGIYGDIYRSTHEMDPQAPPFVEGVLIPITRGWDLPRAGSGRWDIVRRKFLTRQPLRLQCRCTISDEFRDLLTANGENPEEFERLINRSRNDALQFVEQAVARINQKGVIFLLRLDHETLTQLFSVE", "md5" : "e818255ca79d8fb975e125dc2b604751", "matches" : [ ], "xref" : [ { "name" : "XP_018909767.1 PREDICTED: uncharacterized protein LOC109038945 isoform X4 [Bemisia tabaci]", "id" : "XP_018909767.1" } ] },{ "sequence" : "MPTFAASEEASLLGAMPSDSMDDIELQNVQLQFPSARSLSREGSDVEEIKVETDRGHLLVAVQGNRSKPAIVTYHDLGLNYVSSFQAFFNYLDMRQLLNNFSVYHVNAPGQEEGAPPFPDDYEYPTMDDLAAQLNFVLTHFGLRSIIGLGVGAGGNILARFALSNPDKVEALCLINVVSTAAGWIEWGYQKLNARYLRSKGMTQGVLDYLMWHHFGRGTEERNHDLVQVYRNYFERCVNPGNLALFIDSYIRRTDLNIERDPDPNRRKEGGGSPTLSMPVMNITGSLSPHVNDTVTLNSRLDPSNSSWMKISDCGMVLEEQPNKVCEALRLFLQGLGYAVKLGRPKITNSTSAEAFIVMSVKTSRSLDSVRSAPWSIRITENPISETAAC", "md5" : "89a44af05f154f0c346defc7f9a41f4e", "matches" : [ { "signature" : { "accession" : "PTHR11034:SF19", "name" : "GH09802P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 49, "end" : 347, "hmmStart" : 3, "hmmEnd" : 294, "hmmLength" : 301, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 30, "envelopeEnd" : 359, "location-fragments" : [ { "start" : 49, "end" : 347, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-128, "familyName" : "GH09802P", "score" : 429.7, "model-ac" : "PTHR11034:SF19" }, { "signature" : { "accession" : "SSF53474", "name" : "alpha/beta-Hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 334, "hmmLength" : 281, "location-fragments" : [ { "start" : 46, "end" : 334, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.92E-26, "model-ac" : "0046077" }, { "signature" : { "accession" : "PF03096", "name" : "Ndr", "description" : "Ndr family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004142", "name" : "NDRG", "description" : "NDRG", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 338, "hmmStart" : 3, "hmmEnd" : 281, "hmmLength" : 283, "hmmBounds" : "INCOMPLETE", "evalue" : 1.4E-103, "score" : 345.5, "envelopeStart" : 48, "envelopeEnd" : 340, "postProcessed" : true, "location-fragments" : [ { "start" : 50, "end" : 338, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-103, "score" : 345.8, "model-ac" : "PF03096" }, { "signature" : { "accession" : "G3DSA:3.40.50.1820", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 39, "end" : 335, "hmmStart" : 9, "hmmEnd" : 286, "hmmLength" : 286, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-93, "score" : 314.5, "envelopeStart" : 39, "envelopeEnd" : 335, "postProcessed" : true, "location-fragments" : [ { "start" : 39, "end" : 335, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-93, "score" : 314.8, "model-ac" : "2qmqA00" }, { "signature" : { "accession" : "PTHR11034", "name" : "N-MYC DOWNSTREAM REGULATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR004142", "name" : "NDRG", "description" : "NDRG", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 49, "end" : 347, "hmmStart" : 3, "hmmEnd" : 294, "hmmLength" : 301, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 30, "envelopeEnd" : 359, "location-fragments" : [ { "start" : 49, "end" : 347, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-128, "familyName" : "GH09802P", "score" : 429.7, "model-ac" : "PTHR11034" } ], "xref" : [ { "name" : "XP_018910093.1 PREDICTED: protein NDRG3 isoform X5 [Bemisia tabaci]", "id" : "XP_018910093.1" } ] },{ "sequence" : "MLIAYLQKVIINKHTFHAALIIRLLNLAIVQSWFSPDEYWQSLEVAHKFVFGNGYLTWEWQYGIRSYAYVAFISLIYKILRVLHLDSVFLLTNVPRILQAVFSAYADSCFVEWVRRETNLKQGAFALYAYYTSWFIAFCSTRTLINTVELNVTAIALLYYPFKKQHRPDSRFLWFVSFLCLMRPTAAIVWLPLCVFHLLEVENSLAALITSYLPIGLTALTISTLLDSYLHGSLVFTSFNFFWFNIFHNIGVHYGSHSFHWYLTQGLPVVLGPFLLPLIRGPIEFTPIYRKLTLSILFSVLILSLIPHKEFRFLLPLMPAMMFILSNRLFTWFRRIKNQNFANLLIICAAIINFGTLIFFGMFHQIGALTILNKVPVKPNTNLLILTPCHSTPLYSHIHANISIRFLTCEPNLKTLPNYSDEADRFYEDPLKWLHEEFKNGTNLPSHIISFERLSDPILPFLHSNSYRLIERIFHAVFSPDDRISSHICLFEKYR", "md5" : "0693271ffae876ab3bd362f659616361", "matches" : [ { "signature" : { "accession" : "PF03901", "name" : "Glyco_transf_22", "description" : "Alg9-like mannosyltransferase family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005599", "name" : "GPI_mannosylTrfase", "description" : "GPI mannosyltransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "transferase activity, transferring glycosyl groups", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016757" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 15, "end" : 399, "hmmStart" : 2, "hmmEnd" : 417, "hmmLength" : 417, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.4E-87, "score" : 293.0, "envelopeStart" : 14, "envelopeEnd" : 399, "postProcessed" : true, "location-fragments" : [ { "start" : 15, "end" : 399, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-87, "score" : 293.2, "model-ac" : "PF03901" }, { "signature" : { "accession" : "PTHR22760:SF4", "name" : "GPI MANNOSYLTRANSFERASE 3", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR039521", "name" : "PIG-B/GPI10", "description" : "GPI mannosyltransferase 3", "type" : "FAMILY", "goXRefs" : [ { "name" : "GPI anchor biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006506" }, { "name" : "glycolipid mannosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004376" }, { "name" : "alpha-1,2-mannosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0000026" } ], "pathwayXRefs" : [ { "name" : "Synthesis of glycosylphosphatidylinositol (GPI)", "databaseName" : "Reactome", "id" : "R-HSA-162710" } ] } }, "locations" : [ { "start" : 12, "end" : 491, "hmmStart" : 38, "hmmEnd" : 550, "hmmLength" : 552, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 493, "location-fragments" : [ { "start" : 12, "end" : 491, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-136, "familyName" : "GPI MANNOSYLTRANSFERASE 3", "score" : 457.2, "model-ac" : "PTHR22760:SF4" }, { "signature" : { "accession" : "PTHR22760", "name" : "GLYCOSYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR005599", "name" : "GPI_mannosylTrfase", "description" : "GPI mannosyltransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "transferase activity, transferring glycosyl groups", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016757" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 12, "end" : 491, "hmmStart" : 38, "hmmEnd" : 550, "hmmLength" : 552, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 493, "location-fragments" : [ { "start" : 12, "end" : 491, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-136, "familyName" : "GPI MANNOSYLTRANSFERASE 3", "score" : 457.2, "model-ac" : "PTHR22760" } ], "xref" : [ { "name" : "XP_018910258.1 PREDICTED: GPI mannosyltransferase 3 [Bemisia tabaci]", "id" : "XP_018910258.1" } ] },{ "sequence" : "MKLGNFLILSFVIGAISEEDSTEPAFSDQDNAYTNVTVVVLPDHDQDLNSTSEDTKTQKRGIFGVGYGLGQGTGYYGPSVYAPAAYGVPGGYGHTLGGYAVGHGVKFSGIPGGVYNHAPAPAPFYGFNYGYKLGQPISHGVVKAVTIHQEVPVAVPQPYPVPVEKKVPYPVKVPYAVPVDRPYPVHVPKPYPVTVEKPVPYPVEKPVPYPVKVPVKVPVSHPVPYPVPKPYPVPVSKPVPVPYPQPVYIKKTIPVYIGGSGGGHSYPLPPSSSGSVYPPSSSGSIYPPSSGSSGWYPPSSSGWYPPSSSGHTPPTKYHNPTYINAMGGFANTAGGLGKYGGIAAGSVPYGPIGSYSEHPEVVSTLDGEHSSSSDPSGPNIGAPESYESPSYSDEAHMTQISRVPPPNALLNHAVLNIKFLGEFLVMIAKMYIDYETSIKRTCQTEALILCCRFLILKLSHMHYLLPGKLSVGLTLLTALALASFVYAEDKTTTKAAEKDGKKQDKRGLFGLGYGYDSYSGYGLGYGHDSFDSFGHGLGSYGSYGGYGSGYGHGHVSHVTTTLTKEVAVPVPVPQPYPVHVEKHVPVPVPVKVAVPVDRPYPVHVPKPYPVAVEKPVPYPVEKPVPYPVHVPVKVPVAHPVPYPVPKPYPVAVEKHVPVPYPQPVYIEKSHGYGHGYGHGSYGSYGSYGHGDFSGLSLHGGYSSYH", "md5" : "da80c6cf86bdfef7ebb922268d03069c", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 365, "end" : 397, "location-fragments" : [ { "start" : 365, "end" : 397, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 358, "end" : 398, "location-fragments" : [ { "start" : 358, "end" : 398, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR47771", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 475, "end" : 665, "hmmStart" : 6, "hmmEnd" : 218, "hmmLength" : 289, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 468, "envelopeEnd" : 675, "location-fragments" : [ { "start" : 475, "end" : 665, "dc-status" : "CONTINUOUS" } ] }, { "start" : 45, "end" : 256, "hmmStart" : 26, "hmmEnd" : 240, "hmmLength" : 289, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 34, "envelopeEnd" : 269, "location-fragments" : [ { "start" : 45, "end" : 256, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.4E-102, "familyName" : "FAMILY NOT NAMED", "score" : 343.3, "model-ac" : "PTHR47771" } ], "xref" : [ { "name" : "XP_018909777.1 PREDICTED: uncharacterized protein LOC109038955 [Bemisia tabaci]", "id" : "XP_018909777.1" } ] },{ "sequence" : "MKEMVGGCCVCSDERGWAENPLVYCDGQGCTVAVHQACYGIVSVPQGNWYCRKCESQERSARVRCELCPCKDGALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPILLHQIPPERFNKTCYICEENGKGSKATNGACMQCNKAGCRQQFHVTCAQAMGLLCEEAGNYLDNVKYCGYCQHHYSKLKKGGNVKPIPPYRPVPSTNPLDSSPEKETIDKSVPKRKTSSTTKSGGPVITSTDKPGVLKLSISTKGSSVEINSAAEESSTLSAQPAAIPTSTSSSVKSELSDKFTTLNFVESIVAPSESVFGDSKNKKRKGGARTPPNSAPKDSEVSPSDEKDAKKMLDINATEQGGDANAPSVVVKAEGAYPSPSSAAPLTPGSGFSSPAVSKASSTNSATPTTNSIVVSVPYSTAAPAIASTNAAAHGSDMSPAKRSRSQSNEKSEKGKKKRHSVSGSTSPAGGKKSLAGSRTSSPTPDTNAAPKDSPPSSPEISNKKGNNSTTKGRRGSMSLSQPQPQPQAQPVKDEKETKLFQNGVVNAPHMLGNQLNPSSMMAQKMTDTLNAELEAHSIYRAEPNASLVGPQLYSRVISEARSGRSTPNANLSTSTTVTTAATTTTSTASSNGAVSWSSLGGGNIPQTLDQLLERQWEHGSQFLMEQAQHFDIASLLSCLHQLRAENLRLEEHVNSLVQRRDHLLAVNARLAIPLTPVTQVNNVHPATVQQVNESRTSAIHSVGAQQRINNVYSQPPPMENGLSASPPTMYQHRNPHQQPPQSSPNIRSVPSNANMAASGSSIQSGGYSTAMYSMPTSQQQVRTSYEPNLSH", "md5" : "5512acb3d1f68b1aa588a780bb04306f", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 670, "end" : 690, "location-fragments" : [ { "start" : 670, "end" : 690, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PS51805", "name" : "EPHD", "description" : "Extended PHD (ePHD) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR034732", "name" : "EPHD", "description" : "Extended PHD (ePHD) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 62, "end" : 181, "score" : 28.175, "alignment" : "RVRCELCPCK--DGALKKTDNS-GWAHVVCALYIPEVRFGNVTT-MEPILLHQIPPERFNKTCYICEENgkgskatnGACMQCNKAGCRQQFHVTCAQAMGLLCEeAGNYLDNVKycGYCQHHY", "location-fragments" : [ { "start" : 62, "end" : 181, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51805" }, { "signature" : { "accession" : "cd15574", "name" : "PHD_AF10_AF17", "description" : "PHD_AF10_AF17", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 54, "sites" : [ { "description" : "Zn binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 30, "end" : 30, "residue" : "C" }, { "start" : 38, "end" : 38, "residue" : "C" }, { "start" : 54, "end" : 54, "residue" : "C" }, { "start" : 11, "end" : 11, "residue" : "C" }, { "start" : 51, "end" : 51, "residue" : "C" }, { "start" : 25, "end" : 25, "residue" : "C" }, { "start" : 8, "end" : 8, "residue" : "C" }, { "start" : 35, "end" : 35, "residue" : "H" } ] }, { "description" : "putative histone H3 binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 49, "end" : 49, "residue" : "W" }, { "start" : 21, "end" : 21, "residue" : "P" }, { "start" : 7, "end" : 7, "residue" : "G" }, { "start" : 23, "end" : 23, "residue" : "V" }, { "start" : 25, "end" : 25, "residue" : "C" }, { "start" : 22, "end" : 22, "residue" : "L" }, { "start" : 24, "end" : 24, "residue" : "Y" }, { "start" : 31, "end" : 31, "residue" : "T" } ] } ], "evalue" : 1.12711E-32, "score" : 117.999, "location-fragments" : [ { "start" : 7, "end" : 54, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd15574" }, { "signature" : { "accession" : "PS50016", "name" : "ZF_PHD_2", "description" : "Zinc finger PHD-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR019787", "name" : "Znf_PHD-finger", "description" : "Zinc finger, PHD-finger", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5, "end" : 57, "score" : 9.712, "alignment" : "VGGCCVCSDERGWaENPLVYCDgqGCTVAVHQACYGIVSV----PQGNWYCRKCESQ", "location-fragments" : [ { "start" : 5, "end" : 57, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50016" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 595, "end" : 615, "location-fragments" : [ { "start" : 595, "end" : 615, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR13793", "name" : "PHD FINGER PROTEINS", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 811, "hmmStart" : 2, "hmmEnd" : 873, "hmmLength" : 957, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 820, "location-fragments" : [ { "start" : 1, "end" : 811, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-199, "familyName" : "ALHAMBRA, ISOFORM P", "score" : 667.2, "model-ac" : "PTHR13793" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 306, "end" : 531, "location-fragments" : [ { "start" : 306, "end" : 531, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57903", "name" : "FYVE/PHD zinc finger", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011011", "name" : "Znf_FYVE_PHD", "description" : "Zinc finger, FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 70, "hmmLength" : 88, "location-fragments" : [ { "start" : 7, "end" : 70, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.02E-11, "model-ac" : "0050474" }, { "signature" : { "accession" : "PTHR13793:SF106", "name" : "ALHAMBRA, ISOFORM P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 811, "hmmStart" : 2, "hmmEnd" : 873, "hmmLength" : 957, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 820, "location-fragments" : [ { "start" : 1, "end" : 811, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-199, "familyName" : "ALHAMBRA, ISOFORM P", "score" : 667.2, "model-ac" : "PTHR13793:SF106" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 738, "end" : 822, "location-fragments" : [ { "start" : 738, "end" : 822, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 373, "end" : 433, "location-fragments" : [ { "start" : 373, "end" : 433, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 452, "end" : 521, "location-fragments" : [ { "start" : 452, "end" : 521, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 330, "end" : 344, "location-fragments" : [ { "start" : 330, "end" : 344, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd15672", "name" : "ePHD_AF10_like", "description" : "ePHD_AF10_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 65, "end" : 180, "sites" : [ { "description" : "putative histone H3 binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 139, "end" : 139, "residue" : "Q" }, { "start" : 136, "end" : 136, "residue" : "A" }, { "start" : 138, "end" : 138, "residue" : "M" }, { "start" : 140, "end" : 140, "residue" : "C" }, { "start" : 137, "end" : 137, "residue" : "C" }, { "start" : 175, "end" : 175, "residue" : "G" }, { "start" : 119, "end" : 119, "residue" : "T" }, { "start" : 146, "end" : 146, "residue" : "R" } ] }, { "description" : "Zn binding site", "numLocations" : 12, "siteLocations" : [ { "start" : 180, "end" : 180, "residue" : "H" }, { "start" : 123, "end" : 123, "residue" : "C" }, { "start" : 68, "end" : 68, "residue" : "C" }, { "start" : 140, "end" : 140, "residue" : "C" }, { "start" : 65, "end" : 65, "residue" : "C" }, { "start" : 145, "end" : 145, "residue" : "C" }, { "start" : 153, "end" : 153, "residue" : "C" }, { "start" : 177, "end" : 177, "residue" : "C" }, { "start" : 85, "end" : 85, "residue" : "H" }, { "start" : 150, "end" : 150, "residue" : "H" }, { "start" : 88, "end" : 88, "residue" : "C" }, { "start" : 120, "end" : 120, "residue" : "C" } ] } ], "evalue" : 5.21142E-78, "score" : 245.448, "location-fragments" : [ { "start" : 65, "end" : 180, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd15672" }, { "signature" : { "accession" : "PF13832", "name" : "zf-HC5HC2H_2", "description" : "PHD-zinc-finger like domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 64, "end" : 180, "hmmStart" : 2, "hmmEnd" : 110, "hmmLength" : 110, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.2E-30, "score" : 105.9, "envelopeStart" : 63, "envelopeEnd" : 180, "postProcessed" : true, "location-fragments" : [ { "start" : 64, "end" : 180, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-31, "score" : 106.3, "model-ac" : "PF13832" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 434, "end" : 450, "location-fragments" : [ { "start" : 434, "end" : 450, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.40.10", "name" : "Zinc/RING finger domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013083", "name" : "Znf_RING/FYVE/PHD", "description" : "Zinc finger, RING/FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 61, "hmmStart" : 19, "hmmEnd" : 67, "hmmLength" : 71, "hmmBounds" : "COMPLETE", "evalue" : 2.2E-17, "score" : 64.3, "envelopeStart" : 2, "envelopeEnd" : 61, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 61, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-17, "score" : 64.3, "model-ac" : "2ku3A00" }, { "signature" : { "accession" : "G3DSA:3.30.40.10", "name" : "Zinc/RING finger domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013083", "name" : "Znf_RING/FYVE/PHD", "description" : "Zinc finger, RING/FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 104, "end" : 184, "hmmStart" : 9, "hmmEnd" : 83, "hmmLength" : 87, "hmmBounds" : "COMPLETE", "evalue" : 8.9E-19, "score" : 69.5, "envelopeStart" : 104, "envelopeEnd" : 184, "postProcessed" : true, "location-fragments" : [ { "start" : 104, "end" : 184, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.9E-19, "score" : 69.5, "model-ac" : "2lq6A00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 192, "end" : 237, "location-fragments" : [ { "start" : 192, "end" : 237, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS01359", "name" : "ZF_PHD_1", "description" : "Zinc finger PHD-type signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019786", "name" : "Zinc_finger_PHD-type_CS", "description" : "Zinc finger, PHD-type, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 54, "level" : "STRONG", "cigarAlignment" : "1M2I1M11I1M1I1M4I1M3I2M2I1M10I1M1I1M2I1M", "alignment" : "CcvCsdergwaenplVyCdgqgCtvaVHqaCygivsvpqgnWyCrkC", "location-fragments" : [ { "start" : 8, "end" : 54, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01359" }, { "signature" : { "accession" : "SM00249", "name" : "PHD_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001965", "name" : "Znf_PHD", "description" : "Zinc finger, PHD-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 119, "end" : 178, "hmmStart" : 1, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "COMPLETE", "evalue" : 0.015, "score" : 24.5, "location-fragments" : [ { "start" : 119, "end" : 178, "dc-status" : "CONTINUOUS" } ] }, { "start" : 7, "end" : 55, "hmmStart" : 1, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-6, "score" : 37.8, "location-fragments" : [ { "start" : 7, "end" : 55, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-14, "score" : 62.3, "model-ac" : "SM00249" }, { "signature" : { "accession" : "PF13831", "name" : "PHD_2", "description" : "PHD-finger", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 20, "end" : 55, "hmmStart" : 2, "hmmEnd" : 36, "hmmLength" : 36, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.4E-12, "score" : 46.9, "envelopeStart" : 19, "envelopeEnd" : 55, "postProcessed" : true, "location-fragments" : [ { "start" : 20, "end" : 55, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-12, "score" : 46.9, "model-ac" : "PF13831" } ], "xref" : [ { "name" : "XP_018909862.1 PREDICTED: protein AF-10-like isoform X4 [Bemisia tabaci]", "id" : "XP_018909862.1" } ] },{ "sequence" : "MLDSSSLSIFQDVLSKQADIQLNGARPWDPKILHPDCYERCIRDGSLGFGESYMDGWWECEQLDGFCYRVLKARLDEFQPHSIHDVIKMIYDRFFNPRANTVIKHLPIRMNDIINVLSVKLFNLQTKSLAWKVNELHYNLGNDLFVRMLGPHMQYSCGYWRNATTFEESEENKVRLICEKLHLEPGMRVLDIGCGFGGLAAYMARNYDVSVTGITLSKEQARFAREHCKGLDVTILLRDYRDLEGQFDRVVSVEMIEHVGPKNYANFFDVVDRCLGPDGIFVLHVISSNRTVEKHDDWFDKYLFPNGCFPSLKQLAEASEPFFVVEDLHNIGADFDKTMMAWCERFVDAWPEISQSYDERFKRMFIYYLNCAAGGFRARRVQVWHVVFSRGREGGLCVPR", "md5" : "8b93be5dd83b0ec2aa7e8c904b9a27d5", "matches" : [ { "signature" : { "accession" : "PIRSF003085", "name" : "CmaB", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR003333", "name" : "Mycolic_cyclopropane_synthase", "description" : "Mycolic acid cyclopropane synthase", "type" : "FAMILY", "goXRefs" : [ { "name" : "lipid biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0008610" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 9, "end" : 398, "hmmStart" : 35, "hmmEnd" : 393, "hmmLength" : 412, "hmmBounds" : "INCOMPLETE", "evalue" : 1.7E-102, "score" : 339.0, "envelopeStart" : 9, "envelopeEnd" : 398, "postProcessed" : false, "location-fragments" : [ { "start" : 9, "end" : 398, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-102, "score" : 339.5, "model-ac" : "PIRSF003085" }, { "signature" : { "accession" : "SM00828", "name" : "PKS_MT", "description" : "Methyltransferase in polyketide synthase (PKS) enzymes.", "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR020803", "name" : "PKS_MeTfrase", "description" : "Polyketide synthase, methyltransferase domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 154, "end" : 379, "hmmStart" : 1, "hmmEnd" : 275, "hmmLength" : 275, "hmmBounds" : "COMPLETE", "evalue" : 0.0095, "score" : -92.2, "location-fragments" : [ { "start" : 154, "end" : 379, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0095, "score" : -92.2, "model-ac" : "SM00828" }, { "signature" : { "accession" : "cd02440", "name" : "AdoMet_MTases", "description" : "AdoMet_MTases", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 188, "end" : 286, "sites" : [ { "description" : "S-adenosylmethionine binding site", "numLocations" : 13, "siteLocations" : [ { "start" : 193, "end" : 193, "residue" : "G" }, { "start" : 196, "end" : 196, "residue" : "F" }, { "start" : 192, "end" : 192, "residue" : "I" }, { "start" : 197, "end" : 197, "residue" : "G" }, { "start" : 198, "end" : 198, "residue" : "G" }, { "start" : 216, "end" : 216, "residue" : "L" }, { "start" : 238, "end" : 238, "residue" : "R" }, { "start" : 240, "end" : 240, "residue" : "Y" }, { "start" : 194, "end" : 194, "residue" : "C" }, { "start" : 215, "end" : 215, "residue" : "T" }, { "start" : 239, "end" : 239, "residue" : "D" }, { "start" : 253, "end" : 253, "residue" : "V" }, { "start" : 195, "end" : 195, "residue" : "G" } ] } ], "evalue" : 1.17442E-14, "score" : 67.455, "location-fragments" : [ { "start" : 188, "end" : 286, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd02440" }, { "signature" : { "accession" : "SSF53335", "name" : "S-adenosyl-L-methionine-dependent methyltransferases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029063", "name" : "SAM-dependent_MTases", "description" : "S-adenosyl-L-methionine-dependent methyltransferase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 137, "end" : 390, "hmmLength" : 280, "location-fragments" : [ { "start" : 137, "end" : 390, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.08E-71, "model-ac" : "0052709" }, { "signature" : { "accession" : "PF02353", "name" : "CMAS", "description" : "Mycolic acid cyclopropane synthetase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 130, "end" : 385, "hmmStart" : 6, "hmmEnd" : 272, "hmmLength" : 273, "hmmBounds" : "INCOMPLETE", "evalue" : 1.5E-82, "score" : 276.9, "envelopeStart" : 125, "envelopeEnd" : 386, "postProcessed" : true, "location-fragments" : [ { "start" : 130, "end" : 385, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-82, "score" : 277.3, "model-ac" : "PF02353" }, { "signature" : { "accession" : "PTHR43667", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 124, "end" : 393, "hmmStart" : 6, "hmmEnd" : 284, "hmmLength" : 291, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 110, "envelopeEnd" : 399, "location-fragments" : [ { "start" : 124, "end" : 393, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-85, "familyName" : "FAMILY NOT NAMED", "score" : 287.6, "model-ac" : "PTHR43667" }, { "signature" : { "accession" : "G3DSA:3.40.50.150", "name" : "Vaccinia Virus protein VP39", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 135, "end" : 394, "hmmStart" : 4, "hmmEnd" : 277, "hmmLength" : 281, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-89, "score" : 302.3, "envelopeStart" : 135, "envelopeEnd" : 394, "postProcessed" : true, "location-fragments" : [ { "start" : 135, "end" : 394, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.2E-90, "score" : 302.7, "model-ac" : "2fk8A00" } ], "xref" : [ { "name" : "XP_018910011.1 PREDICTED: uncharacterized protein LOC109039113 [Bemisia tabaci]", "id" : "XP_018910011.1" } ] },{ "sequence" : "MKPMLLGPLVVWICCGMVTARQVASARGSDPNKVGNGEAQTLNLDEARMADQGSPYSRVPLVYGPRSARLREGATALDMVRNMYDECLSEGSFSCVKPKILAFLSASSDKENIRLTRDLSIVKAPSYVEPAPEYYLQTPDQSPDDAEKKQALRMLMLDKVDDFLSSHELQIRIPKEIISGSIAPFVPSALMKNIPQEMRIPLAEPETGKGRGLAKKVIMPFLLGLKFKATAVIPLALAFIALKTWKALTLGLLSVVLSGAMIIFKFSKPPRLVNYEVVHYQHHPPPPPPPAVVEHPIAYDHHHPYRRSVEPQQLAYSAHRV", "md5" : "00918544dd3578b3627f98e6d4e7cf5b", "matches" : [ { "signature" : { "accession" : "PF07898", "name" : "DUF1676", "description" : "Protein of unknown function (DUF1676)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR012464", "name" : "DUF1676", "description" : "Protein of unknown function DUF1676", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 86, "end" : 265, "hmmStart" : 1, "hmmEnd" : 172, "hmmLength" : 172, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-36, "score" : 126.1, "envelopeStart" : 86, "envelopeEnd" : 265, "postProcessed" : true, "location-fragments" : [ { "start" : 86, "end" : 265, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-36, "score" : 126.5, "model-ac" : "PF07898" }, { "signature" : { "accession" : "PTHR21879", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR012464", "name" : "DUF1676", "description" : "Protein of unknown function DUF1676", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 75, "end" : 306, "hmmStart" : 25, "hmmEnd" : 232, "hmmLength" : 267, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 61, "envelopeEnd" : 320, "location-fragments" : [ { "start" : 75, "end" : 306, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-64, "familyName" : "OSIRIS 18", "score" : 220.9, "model-ac" : "PTHR21879" }, { "signature" : { "accession" : "PTHR21879:SF13", "name" : "OSIRIS 18", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 75, "end" : 306, "hmmStart" : 25, "hmmEnd" : 232, "hmmLength" : 267, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 61, "envelopeEnd" : 320, "location-fragments" : [ { "start" : 75, "end" : 306, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-64, "familyName" : "OSIRIS 18", "score" : 220.9, "model-ac" : "PTHR21879:SF13" } ], "xref" : [ { "name" : "XP_018909787.1 PREDICTED: uncharacterized protein LOC109038963 [Bemisia tabaci]", "id" : "XP_018909787.1" } ] },{ "sequence" : "MITSKYLLLIIFYLHCVRCSLKPETKHDDILPPCSSCKVLVESFMKGVKRTSRENFAGGDAAWEEEKLGTYATSEVRLIEIQEKLCSEVGRGKDQCLTLSETHEALLEDWWFNEQKVSPDLKQWLCVDLLKVCCPAGHFGADCQPCPGFPKVCFGNGKCKGDGTRKGNGACICDAGYTGEYCDACGPGYYQSYKDDDKLLCSKCHPACSGNCTEAGTKGCEACNEGWAMTAENGCVDVNECVLPDVCKHNQFCVNEEGNYSCIECDAACSGCYGDGPDMCIKCAPGYFLQDNFCVEDFFDGSSNHLCHLSDYWSFLRHDSYCPKL", "md5" : "307f6b0777fc29d0191ec42d863546b2", "matches" : [ { "signature" : { "accession" : "PTHR24034", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 296, "hmmStart" : 22, "hmmEnd" : 290, "hmmLength" : 353, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 314, "location-fragments" : [ { "start" : 25, "end" : 296, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-65, "familyName" : "CYSTEINE-RICH WITH EGF-LIKE DOMAIN PROTEIN 2", "score" : 223.2, "model-ac" : "PTHR24034" }, { "signature" : { "accession" : "SSF57184", "name" : "Growth factor receptor domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009030", "name" : "Growth_fac_rcpt_cys_sf", "description" : "Growth factor receptor cysteine-rich domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 171, "end" : 297, "hmmLength" : 145, "location-fragments" : [ { "start" : 171, "end" : 297, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.28E-14, "model-ac" : "0048103" }, { "signature" : { "accession" : "cd00064", "name" : "FU", "description" : "FU", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR006212", "name" : "Furin_repeat", "description" : "Furin-like repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 264, "end" : 297, "sites" : [ ], "evalue" : 1.55662E-4, "score" : 36.728, "location-fragments" : [ { "start" : 264, "end" : 297, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00064" }, { "signature" : { "accession" : "PS01248", "name" : "EGF_LAM_1", "description" : "Laminin-type EGF-like (LE) domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR002049", "name" : "Laminin_EGF", "description" : "Laminin EGF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 171, "end" : 204, "level" : "STRONG", "cigarAlignment" : "1M1I1M5I1M2I1M2I1M4I1M13I1M", "alignment" : "CiCdagytGeyCdaCgpgyYqsykdddkllcskC", "location-fragments" : [ { "start" : 171, "end" : 204, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01248" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 142, "end" : 183, "score" : 10.747, "alignment" : "DCQPCPgfpKVCFGNGKCKGDGTrKGNGACICDAGYTGEYCD", "location-fragments" : [ { "start" : 142, "end" : 183, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "PTHR24034:SF110", "name" : "CYSTEINE-RICH WITH EGF-LIKE DOMAIN PROTEIN 2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 296, "hmmStart" : 22, "hmmEnd" : 290, "hmmLength" : 353, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 314, "location-fragments" : [ { "start" : 25, "end" : 296, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-65, "familyName" : "CYSTEINE-RICH WITH EGF-LIKE DOMAIN PROTEIN 2", "score" : 223.2, "model-ac" : "PTHR24034:SF110" }, { "signature" : { "accession" : "G3DSA:2.10.220.10", "name" : "Hormone Receptor", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 211, "end" : 318, "hmmStart" : 8, "hmmEnd" : 98, "hmmLength" : 120, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-5, "score" : 26.6, "envelopeStart" : 211, "envelopeEnd" : 318, "postProcessed" : true, "location-fragments" : [ { "start" : 211, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-5, "score" : 26.6, "model-ac" : "4ufrB00" }, { "signature" : { "accession" : "PS01187", "name" : "EGF_CA", "description" : "Calcium-binding EGF-like domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018097", "name" : "EGF_Ca-bd_CS", "description" : "EGF-like calcium-binding, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 237, "end" : 262, "level" : "STRONG", "cigarAlignment" : "1M1I3M5I1M5I1M1I1M4I1M1I1M", "alignment" : "DvNECvlpdvCkhnqfCvNeegnYsC", "location-fragments" : [ { "start" : 237, "end" : 262, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01187" }, { "signature" : { "accession" : "SM00261", "name" : "furin_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006212", "name" : "Furin_repeat", "description" : "Furin-like repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 198, "end" : 253, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 2.4, "score" : 17.1, "location-fragments" : [ { "start" : 198, "end" : 253, "dc-status" : "CONTINUOUS" } ] }, { "start" : 259, "end" : 300, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-7, "score" : 40.2, "location-fragments" : [ { "start" : 259, "end" : 300, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-12, "score" : 57.3, "model-ac" : "SM00261" }, { "signature" : { "accession" : "PS00022", "name" : "EGF_1", "description" : "EGF-like domain signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 171, "end" : 182, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I1M2I2M1I1M", "alignment" : "CiCdaGytGEyC", "location-fragments" : [ { "start" : 171, "end" : 182, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00022" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 237, "end" : 263, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 237, "end" : 237, "residue" : "D" }, { "start" : 240, "end" : 240, "residue" : "E" }, { "start" : 255, "end" : 255, "residue" : "N" } ] } ], "evalue" : 0.00208353, "score" : 33.379, "location-fragments" : [ { "start" : 237, "end" : 263, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" } ], "xref" : [ { "name" : "XP_018909886.1 PREDICTED: cysteine-rich with EGF-like domain protein 2 isoform X3 [Bemisia tabaci]", "id" : "XP_018909886.1" } ] },{ "sequence" : "MYILKNKFNYFPLSKFSISFCVVSCVLPTVLSFNFRRGNVSSYDFRTMNMSPVILIPGVVGSIIEGTWRTHGQPRLCTAKEKDWEVLWLSLKTAFGGKPLKCWVFRYKLIYNRTAHKSSNQDGVKTRVMGDFGSLKAVEHLTKDLITRIGTGYFDDIGKALRKSGYSTKRNLKGAAYDGRYAPPQLEEKYGYFTSLAKLVEQLANDSGRKVTLVSHSMGGLIGSHFLTKQPPEWKDKYINLFVPISTPWLGSPLAVSGFIEGTNFDVPTFKKSVMRDLVRTFQSVALLLLSEEAYNRTVIVEWPEQNKTYTAADYKQLFTDIKYQDGFLMREDVRSLMPVAGDKLGVDIVCIWSKSVKTKFKMVVKGDIANPTSVSYETVDGDGTVTLDSLRYCETFPNVTTQEYTGLDHLKIVYSKDFINYLQSVLVNAKPL", "md5" : "5bbf110a11036cf8a5d33e7c00114864", "matches" : [ { "signature" : { "accession" : "PF02450", "name" : "LCAT", "description" : "Lecithin:cholesterol acyltransferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR003386", "name" : "LACT/PDAT_acylTrfase", "description" : "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "lipid metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006629" }, { "name" : "O-acyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008374" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 87, "end" : 316, "hmmStart" : 6, "hmmEnd" : 228, "hmmLength" : 392, "hmmBounds" : "INCOMPLETE", "evalue" : 7.9E-42, "score" : 143.8, "envelopeStart" : 84, "envelopeEnd" : 341, "postProcessed" : true, "location-fragments" : [ { "start" : 87, "end" : 316, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-43, "score" : 149.7, "model-ac" : "PF02450" }, { "signature" : { "accession" : "PTHR11440:SF35", "name" : "BCDNA.GH02384", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 50, "end" : 427, "hmmStart" : 45, "hmmEnd" : 411, "hmmLength" : 420, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 18, "envelopeEnd" : 431, "location-fragments" : [ { "start" : 50, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-66, "familyName" : "BCDNA.GH02384", "score" : 228.2, "model-ac" : "PTHR11440:SF35" }, { "signature" : { "accession" : "SSF53474", "name" : "alpha/beta-Hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 52, "end" : 421, "hmmLength" : 388, "location-fragments" : [ { "start" : 153, "end" : 421, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 52, "end" : 64, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.09E-19, "model-ac" : "0047879" }, { "signature" : { "accession" : "PTHR11440", "name" : "LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 50, "end" : 427, "hmmStart" : 45, "hmmEnd" : 411, "hmmLength" : 420, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 18, "envelopeEnd" : 431, "location-fragments" : [ { "start" : 50, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-66, "familyName" : "BCDNA.GH02384", "score" : 228.2, "model-ac" : "PTHR11440" } ], "xref" : [ { "name" : "XP_018909704.1 PREDICTED: group XV phospholipase A2-like [Bemisia tabaci]", "id" : "XP_018909704.1" } ] },{ "sequence" : "MGGKGGVFARTGLSIACCVSRVILTFVRICIFCPQLADDNSASWNLPVFLSGFSSRISKINLPMYALARFPLLLLGFVLPVTSVATNQRYNDSRVIPCIVTGVTTI", "md5" : "a93d7df6087dc11962981a26880e5413", "matches" : [ ], "xref" : [ { "name" : "XP_018910282.1 PREDICTED: uncharacterized protein LOC109039312 [Bemisia tabaci]", "id" : "XP_018910282.1" } ] },{ "sequence" : "MTSFLTPNRHGYSVRFSPFDGKKIVVATSQYFGLAGGGTLFALQVTPDDSLVEAGKFEWPDGLFDVVWSETNPDLVVTASGDCSLQLWNLCQDPFPVQIFKEHKKEVYSVDWSQTRTEQLILSASWDCTVKLWDPTRKESLATFPGHSQLVYNAKWSPHVPSCFASVSGDGTLRVWNAQLPQRASISFKVHDAEVLSCSWCKYNLNLLATGGSEGLIRGWDLRNPSCPIFELRGCEYAVRRVQFSPHQASLLGSVSYDFTTRIWDINQSPSAIETIKHHSEFVYGLDFNNLVEGQIADCGWDSLVHVFSPSSLRDREQR", "md5" : "0c37495f27f5dda21e2dd8044aa7f66c", "matches" : [ { "signature" : { "accession" : "PS00678", "name" : "WD_REPEATS_1", "description" : "Trp-Asp (WD) repeats signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019775", "name" : "WD40_repeat_CS", "description" : "WD40 repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 252, "end" : 266, "level" : "STRONG", "cigarAlignment" : "4M2I1M1I7M", "alignment" : "LGSVsyDfTTRIWDI", "location-fragments" : [ { "start" : 252, "end" : 266, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00678" }, { "signature" : { "accession" : "PS50294", "name" : "WD_REPEATS_REGION", "description" : "Trp-Asp (WD) repeats circular profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR017986", "name" : "WD40_repeat_dom", "description" : "WD40-repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 56, "end" : 318, "score" : 33.537, "alignment" : "KFEWPDGLFDVVWSETnPDLVVTASGDCSLQLWNLCQDPFPVQiFKEHKKEVYSVDWSQTrtEQLILSASWDCTVKLWDPTRKESLATFPGHSQLVYNAKWSPHvPSCFASVSGDGTLRVWNAQLPQRASIsFKVHDAEVLSCSWCKYnLNLLATGGSEGLIRGWDLRNPSCPIFeLRGCEYAVRRVQFSPHqASLLGSVSYDFTTRIWDINQSPSAIEtIKHHSEFVYGLDFNNLvEGQIADCGWDSLVHVFSPSSLRDREQ", "location-fragments" : [ { "start" : 56, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50294" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 100, "end" : 143, "score" : 12.48, "alignment" : "FKEHKKEVYSVDWSQTrtEQLILSASWDCTVKLWDPTRKESLAT", "location-fragments" : [ { "start" : 100, "end" : 143, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 309, "hmmStart" : 8, "hmmEnd" : 364, "hmmLength" : 365, "hmmBounds" : "COMPLETE", "evalue" : 6.2E-81, "score" : 274.1, "envelopeStart" : 1, "envelopeEnd" : 309, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 309, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-81, "score" : 274.2, "model-ac" : "3w15A01" }, { "signature" : { "accession" : "SSF50978", "name" : "WD40 repeat-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036322", "name" : "WD40_repeat_dom_sf", "description" : "WD40-repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 12, "end" : 311, "hmmLength" : 388, "location-fragments" : [ { "start" : 12, "end" : 311, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.44E-54, "model-ac" : "0046612" }, { "signature" : { "accession" : "PS00678", "name" : "WD_REPEATS_1", "description" : "Trp-Asp (WD) repeats signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019775", "name" : "WD40_repeat_CS", "description" : "WD40 repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 76, "end" : 90, "level" : "STRONG", "cigarAlignment" : "4M2I1M1I7M", "alignment" : "VVTAsgDcSLQLWNL", "location-fragments" : [ { "start" : 76, "end" : 90, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00678" }, { "signature" : { "accession" : "SM00320", "name" : "WD40_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 93, "end" : 134, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-8, "score" : 43.7, "location-fragments" : [ { "start" : 93, "end" : 134, "dc-status" : "CONTINUOUS" } ] }, { "start" : 137, "end" : 177, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 3.9E-8, "score" : 43.0, "location-fragments" : [ { "start" : 137, "end" : 177, "dc-status" : "CONTINUOUS" } ] }, { "start" : 225, "end" : 265, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 5.5E-4, "score" : 29.2, "location-fragments" : [ { "start" : 225, "end" : 265, "dc-status" : "CONTINUOUS" } ] }, { "start" : 181, "end" : 221, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 5.3E-4, "score" : 29.3, "location-fragments" : [ { "start" : 181, "end" : 221, "dc-status" : "CONTINUOUS" } ] }, { "start" : 269, "end" : 309, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 2.0, "score" : 15.1, "location-fragments" : [ { "start" : 269, "end" : 309, "dc-status" : "CONTINUOUS" } ] }, { "start" : 50, "end" : 89, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 0.34, "score" : 19.9, "location-fragments" : [ { "start" : 50, "end" : 89, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-49, "score" : 180.3, "model-ac" : "SM00320" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 188, "end" : 224, "score" : 8.604, "alignment" : "FKVHDAEVLSCSWCKYnLNLLATGGSEGLIRGWDLRN------", "location-fragments" : [ { "start" : 188, "end" : 224, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "PR00320", "name" : "GPROTEINBRPT", "description" : "G protein beta WD-40 repeat signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR020472", "name" : "G-protein_beta_WD-40_rep", "description" : "G-protein beta WD-40 repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 76, "end" : 90, "pvalue" : 2.89E-4, "score" : 31.33, "motifNumber" : 1, "location-fragments" : [ { "start" : 76, "end" : 90, "dc-status" : "CONTINUOUS" } ] }, { "start" : 164, "end" : 178, "pvalue" : 2.51E-4, "score" : 35.82, "motifNumber" : 3, "location-fragments" : [ { "start" : 164, "end" : 178, "dc-status" : "CONTINUOUS" } ] }, { "start" : 121, "end" : 135, "pvalue" : 3.5E-5, "score" : 41.82, "motifNumber" : 2, "location-fragments" : [ { "start" : 121, "end" : 135, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-6, "graphscan" : "III", "model-ac" : "PR00320" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 232, "end" : 274, "score" : 9.272, "alignment" : "LRGCEYAVRRVQFSPHqASLLGSVSYDFTTRIWDINQSPSAIE", "location-fragments" : [ { "start" : 232, "end" : 274, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 144, "end" : 177, "score" : 11.21, "alignment" : "FPGHSQLVYNAKWSPHvPSCFASVSGDGTLRVWN---------", "location-fragments" : [ { "start" : 144, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "PTHR46027", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 314, "hmmStart" : 1, "hmmEnd" : 314, "hmmLength" : 317, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 317, "location-fragments" : [ { "start" : 1, "end" : 314, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.2E-131, "familyName" : "FAMILY NOT NAMED", "score" : 438.5, "model-ac" : "PTHR46027" }, { "signature" : { "accession" : "PF00400", "name" : "WD40", "description" : "WD domain, G-beta repeat", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 140, "end" : 177, "hmmStart" : 3, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 0.0016, "score" : 19.2, "envelopeStart" : 138, "envelopeEnd" : 177, "postProcessed" : true, "location-fragments" : [ { "start" : 140, "end" : 177, "dc-status" : "CONTINUOUS" } ] }, { "start" : 229, "end" : 265, "hmmStart" : 4, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 0.066, "score" : 14.1, "envelopeStart" : 226, "envelopeEnd" : 265, "postProcessed" : true, "location-fragments" : [ { "start" : 229, "end" : 265, "dc-status" : "CONTINUOUS" } ] }, { "start" : 96, "end" : 134, "hmmStart" : 3, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.9E-5, "score" : 24.7, "envelopeStart" : 95, "envelopeEnd" : 134, "postProcessed" : true, "location-fragments" : [ { "start" : 96, "end" : 134, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-19, "score" : 68.3, "model-ac" : "PF00400" } ], "xref" : [ { "name" : "XP_018910480.1 PREDICTED: peroxisomal targeting signal 2 receptor [Bemisia tabaci]", "id" : "XP_018910480.1" }, { "name" : "XP_018910479.1 PREDICTED: peroxisomal targeting signal 2 receptor [Bemisia tabaci]", "id" : "XP_018910479.1" } ] },{ "sequence" : "MIVKLLRAPRLLSKCVVRNFSAVEPVVNLNERKVFAKRAETNDPATHSENDIGKFYTVSKEDNKKLFSFYEFPAQFERNIKTFNESAFMIREPALEIINSLKTLDPTKPILKFVIYGRFGEGKTMTFCHICHFAHRAGWILCYVPTSTIWMRWSKEVTFSETKPESINIPLESAQWLRNFKIQNADLISKLDLRVRDKIVWSAREITEKDAPLMELVDHGINRVKYAGDVVDVLIENIKLYSTEQRCRTLVAIDGFNGFFNPKSNLKAPDETPVPPLRVTIMQSLMKLTQADWSNGAAVLTVDTKNSYPDNREFVFPLYLLHKEGFEHLDPFIPVYVPALNPKEVNNLLDYYEEKKWLLKPQAREEIEFLSTRNPYHLTELCGPL", "md5" : "2c3f71ea0e1776dce07421f821a5d227", "matches" : [ { "signature" : { "accession" : "PTHR12810", "name" : "MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S29", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR019368", "name" : "Ribosomal_S23/S29_mit", "description" : "Ribosomal protein S23/S29, mitochondrial", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Mitochondrial translation elongation", "databaseName" : "Reactome", "id" : "R-HSA-5389840" }, { "name" : "Mitochondrial translation termination", "databaseName" : "Reactome", "id" : "R-HSA-5419276" }, { "name" : "Mitochondrial translation initiation", "databaseName" : "Reactome", "id" : "R-HSA-5368286" } ] } }, "locations" : [ { "start" : 31, "end" : 385, "hmmStart" : 86, "hmmEnd" : 443, "hmmLength" : 444, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 12, "envelopeEnd" : 385, "location-fragments" : [ { "start" : 31, "end" : 385, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-80, "familyName" : "MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S29", "score" : 272.7, "model-ac" : "PTHR12810" }, { "signature" : { "accession" : "PF10236", "name" : "DAP3", "description" : "Mitochondrial ribosomal death-associated protein 3", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR019368", "name" : "Ribosomal_S23/S29_mit", "description" : "Ribosomal protein S23/S29, mitochondrial", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Mitochondrial translation elongation", "databaseName" : "Reactome", "id" : "R-HSA-5389840" }, { "name" : "Mitochondrial translation termination", "databaseName" : "Reactome", "id" : "R-HSA-5419276" }, { "name" : "Mitochondrial translation initiation", "databaseName" : "Reactome", "id" : "R-HSA-5368286" } ] } }, "locations" : [ { "start" : 89, "end" : 380, "hmmStart" : 2, "hmmEnd" : 311, "hmmLength" : 312, "hmmBounds" : "INCOMPLETE", "evalue" : 2.9E-63, "score" : 213.9, "envelopeStart" : 88, "envelopeEnd" : 381, "postProcessed" : true, "location-fragments" : [ { "start" : 89, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-63, "score" : 214.3, "model-ac" : "PF10236" }, { "signature" : { "accession" : "PR01716", "name" : "DEATHASSOCP3", "description" : "Death associated protein 3 family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR008092", "name" : "Ribosomal_S29_mit", "description" : "Ribosomal protein S29, mitochondrial", "type" : "FAMILY", "goXRefs" : [ { "name" : "mitochondrial ribosome", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005761" }, { "name" : "small ribosomal subunit", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0015935" }, { "name" : "apoptotic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006915" } ], "pathwayXRefs" : [ { "name" : "Mitochondrial translation initiation", "databaseName" : "Reactome", "id" : "R-HSA-5368286" }, { "name" : "Mitochondrial translation termination", "databaseName" : "Reactome", "id" : "R-HSA-5419276" }, { "name" : "Mitochondrial translation elongation", "databaseName" : "Reactome", "id" : "R-HSA-5389840" } ] } }, "locations" : [ { "start" : 91, "end" : 102, "pvalue" : 1.43E-5, "score" : 53.57, "motifNumber" : 2, "location-fragments" : [ { "start" : 91, "end" : 102, "dc-status" : "CONTINUOUS" } ] }, { "start" : 317, "end" : 334, "pvalue" : 8.44E-10, "score" : 66.67, "motifNumber" : 9, "location-fragments" : [ { "start" : 317, "end" : 334, "dc-status" : "CONTINUOUS" } ] }, { "start" : 109, "end" : 126, "pvalue" : 3.61E-8, "score" : 42.06, "motifNumber" : 3, "location-fragments" : [ { "start" : 109, "end" : 126, "dc-status" : "CONTINUOUS" } ] }, { "start" : 215, "end" : 229, "pvalue" : 3.54E-6, "score" : 49.52, "motifNumber" : 7, "location-fragments" : [ { "start" : 215, "end" : 229, "dc-status" : "CONTINUOUS" } ] }, { "start" : 248, "end" : 260, "pvalue" : 1.75E-4, "score" : 49.45, "motifNumber" : 8, "location-fragments" : [ { "start" : 248, "end" : 260, "dc-status" : "CONTINUOUS" } ] }, { "start" : 199, "end" : 210, "pvalue" : 0.00303, "score" : 54.76, "motifNumber" : 6, "location-fragments" : [ { "start" : 199, "end" : 210, "dc-status" : "CONTINUOUS" } ] }, { "start" : 170, "end" : 184, "pvalue" : 5.24E-7, "score" : 58.1, "motifNumber" : 5, "location-fragments" : [ { "start" : 170, "end" : 184, "dc-status" : "CONTINUOUS" } ] }, { "start" : 73, "end" : 85, "pvalue" : 5.81E-5, "score" : 42.86, "motifNumber" : 1, "location-fragments" : [ { "start" : 73, "end" : 85, "dc-status" : "CONTINUOUS" } ] }, { "start" : 132, "end" : 143, "pvalue" : 0.0118, "score" : 27.38, "motifNumber" : 4, "location-fragments" : [ { "start" : 132, "end" : 143, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-40, "graphscan" : "IIIiIIIII", "model-ac" : "PR01716" } ], "xref" : [ { "name" : "XP_018909706.1 PREDICTED: 28S ribosomal protein S29, mitochondrial isoform X1 [Bemisia tabaci]", "id" : "XP_018909706.1" } ] },{ "sequence" : "MRKSMMLLLLMMVSLMVATDAYRVDVFNQKGYGSPNSGKDSKLNQCIWIEKNTAGQVSSVKISADVKDRNKVVKFFSDAKCGSSSFLWASQTSGDVPSAHDKKFRSWRIVEMPHPGGGK", "md5" : "4d96003baf9f8dfc02162cb7cb810687", "matches" : [ ], "xref" : [ { "name" : "XP_018909909.1 PREDICTED: uncharacterized protein LOC109039036 [Bemisia tabaci]", "id" : "XP_018909909.1" } ] },{ "sequence" : "MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGC", "md5" : "f067d53371d99cb3821e0880a1f0c5f9", "matches" : [ { "signature" : { "accession" : "cd01803", "name" : "Ubl_ubiquitin", "description" : "Ubl_ubiquitin", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 153, "end" : 228, "sites" : [ { "description" : "key conserved lysine K27", "numLocations" : 1, "siteLocations" : [ { "start" : 179, "end" : 179, "residue" : "K" } ] }, { "description" : "key conserved lysines", "numLocations" : 7, "siteLocations" : [ { "start" : 215, "end" : 215, "residue" : "K" }, { "start" : 200, "end" : 200, "residue" : "K" }, { "start" : 181, "end" : 181, "residue" : "K" }, { "start" : 158, "end" : 158, "residue" : "K" }, { "start" : 163, "end" : 163, "residue" : "K" }, { "start" : 179, "end" : 179, "residue" : "K" }, { "start" : 185, "end" : 185, "residue" : "K" } ] }, { "description" : "E1 interaction site", "numLocations" : 25, "siteLocations" : [ { "start" : 224, "end" : 224, "residue" : "R" }, { "start" : 200, "end" : 200, "residue" : "K" }, { "start" : 199, "end" : 199, "residue" : "G" }, { "start" : 183, "end" : 183, "residue" : "Q" }, { "start" : 184, "end" : 184, "residue" : "D" }, { "start" : 187, "end" : 187, "residue" : "G" }, { "start" : 220, "end" : 220, "residue" : "H" }, { "start" : 196, "end" : 196, "residue" : "I" }, { "start" : 194, "end" : 194, "residue" : "R" }, { "start" : 226, "end" : 226, "residue" : "R" }, { "start" : 223, "end" : 223, "residue" : "L" }, { "start" : 160, "end" : 160, "residue" : "L" }, { "start" : 161, "end" : 161, "residue" : "T" }, { "start" : 162, "end" : 162, "residue" : "G" }, { "start" : 201, "end" : 201, "residue" : "Q" }, { "start" : 198, "end" : 198, "residue" : "A" }, { "start" : 186, "end" : 186, "residue" : "E" }, { "start" : 192, "end" : 192, "residue" : "Q" }, { "start" : 222, "end" : 222, "residue" : "V" }, { "start" : 228, "end" : 228, "residue" : "G" }, { "start" : 164, "end" : 164, "residue" : "T" }, { "start" : 163, "end" : 163, "residue" : "K" }, { "start" : 225, "end" : 225, "residue" : "L" }, { "start" : 185, "end" : 185, "residue" : "K" }, { "start" : 227, "end" : 227, "residue" : "G" } ] }, { "description" : "oligomer interface", "numLocations" : 25, "siteLocations" : [ { "start" : 224, "end" : 224, "residue" : "R" }, { "start" : 200, "end" : 200, "residue" : "K" }, { "start" : 199, "end" : 199, "residue" : "G" }, { "start" : 187, "end" : 187, "residue" : "G" }, { "start" : 220, "end" : 220, "residue" : "H" }, { "start" : 189, "end" : 189, "residue" : "P" }, { "start" : 196, "end" : 196, "residue" : "I" }, { "start" : 221, "end" : 221, "residue" : "L" }, { "start" : 158, "end" : 158, "residue" : "K" }, { "start" : 194, "end" : 194, "residue" : "R" }, { "start" : 226, "end" : 226, "residue" : "R" }, { "start" : 223, "end" : 223, "residue" : "L" }, { "start" : 188, "end" : 188, "residue" : "I" }, { "start" : 160, "end" : 160, "residue" : "L" }, { "start" : 161, "end" : 161, "residue" : "T" }, { "start" : 201, "end" : 201, "residue" : "Q" }, { "start" : 198, "end" : 198, "residue" : "A" }, { "start" : 159, "end" : 159, "residue" : "T" }, { "start" : 186, "end" : 186, "residue" : "E" }, { "start" : 192, "end" : 192, "residue" : "Q" }, { "start" : 222, "end" : 222, "residue" : "V" }, { "start" : 228, "end" : 228, "residue" : "G" }, { "start" : 163, "end" : 163, "residue" : "K" }, { "start" : 225, "end" : 225, "residue" : "L" }, { "start" : 227, "end" : 227, "residue" : "G" } ] } ], "evalue" : 1.61992E-50, "score" : 157.221, "location-fragments" : [ { "start" : 153, "end" : 228, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01803" }, { "signature" : { "accession" : "PS00299", "name" : "UBIQUITIN_1", "description" : "Ubiquitin domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019954", "name" : "Ubiquitin_CS", "description" : "Ubiquitin conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 179, "end" : 204, "level" : "STRONG", "cigarAlignment" : "1M2I1M1I1M3I2M3I1M1I3M1I1M4I1M", "alignment" : "KakIqDkegIPpdqQrLIFaGkqleD", "location-fragments" : [ { "start" : 179, "end" : 204, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00299" }, { "signature" : { "accession" : "PS50053", "name" : "UBIQUITIN_2", "description" : "Ubiquitin domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000626", "name" : "Ubiquitin-like_dom", "description" : "Ubiquitin-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 77, "end" : 152, "score" : 30.735, "alignment" : "MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG", "location-fragments" : [ { "start" : 77, "end" : 152, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50053" }, { "signature" : { "accession" : "PTHR10666:SF340", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 132, "hmmStart" : 77, "hmmEnd" : 208, "hmmLength" : 305, "hmmBounds" : "COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 132, "location-fragments" : [ { "start" : 1, "end" : 132, "dc-status" : "CONTINUOUS" } ] }, { "start" : 124, "end" : 228, "hmmStart" : 48, "hmmEnd" : 152, "hmmLength" : 305, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 124, "envelopeEnd" : 229, "location-fragments" : [ { "start" : 124, "end" : 228, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-219, "familyName" : "", "score" : 730.3, "model-ac" : "PTHR10666:SF340" }, { "signature" : { "accession" : "PTHR10666:SF340", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 71, "end" : 164, "hmmStart" : 71, "hmmEnd" : 164, "hmmLength" : 305, "hmmBounds" : "COMPLETE", "envelopeStart" : 71, "envelopeEnd" : 164, "location-fragments" : [ { "start" : 71, "end" : 164, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-219, "familyName" : "", "score" : 730.3, "model-ac" : "PTHR10666:SF340" }, { "signature" : { "accession" : "cd01803", "name" : "Ubl_ubiquitin", "description" : "Ubl_ubiquitin", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 77, "end" : 152, "sites" : [ { "description" : "key conserved lysines", "numLocations" : 7, "siteLocations" : [ { "start" : 82, "end" : 82, "residue" : "K" }, { "start" : 87, "end" : 87, "residue" : "K" }, { "start" : 103, "end" : 103, "residue" : "K" }, { "start" : 109, "end" : 109, "residue" : "K" }, { "start" : 139, "end" : 139, "residue" : "K" }, { "start" : 124, "end" : 124, "residue" : "K" }, { "start" : 105, "end" : 105, "residue" : "K" } ] }, { "description" : "oligomer interface", "numLocations" : 25, "siteLocations" : [ { "start" : 82, "end" : 82, "residue" : "K" }, { "start" : 118, "end" : 118, "residue" : "R" }, { "start" : 150, "end" : 150, "residue" : "R" }, { "start" : 148, "end" : 148, "residue" : "R" }, { "start" : 124, "end" : 124, "residue" : "K" }, { "start" : 123, "end" : 123, "residue" : "G" }, { "start" : 83, "end" : 83, "residue" : "T" }, { "start" : 110, "end" : 110, "residue" : "E" }, { "start" : 144, "end" : 144, "residue" : "H" }, { "start" : 113, "end" : 113, "residue" : "P" }, { "start" : 120, "end" : 120, "residue" : "I" }, { "start" : 145, "end" : 145, "residue" : "L" }, { "start" : 87, "end" : 87, "residue" : "K" }, { "start" : 149, "end" : 149, "residue" : "L" }, { "start" : 151, "end" : 151, "residue" : "G" }, { "start" : 147, "end" : 147, "residue" : "L" }, { "start" : 112, "end" : 112, "residue" : "I" }, { "start" : 84, "end" : 84, "residue" : "L" }, { "start" : 85, "end" : 85, "residue" : "T" }, { "start" : 125, "end" : 125, "residue" : "Q" }, { "start" : 122, "end" : 122, "residue" : "A" }, { "start" : 111, "end" : 111, "residue" : "G" }, { "start" : 116, "end" : 116, "residue" : "Q" }, { "start" : 146, "end" : 146, "residue" : "V" }, { "start" : 152, "end" : 152, "residue" : "G" } ] }, { "description" : "E1 interaction site", "numLocations" : 25, "siteLocations" : [ { "start" : 118, "end" : 118, "residue" : "R" }, { "start" : 150, "end" : 150, "residue" : "R" }, { "start" : 148, "end" : 148, "residue" : "R" }, { "start" : 124, "end" : 124, "residue" : "K" }, { "start" : 123, "end" : 123, "residue" : "G" }, { "start" : 110, "end" : 110, "residue" : "E" }, { "start" : 144, "end" : 144, "residue" : "H" }, { "start" : 120, "end" : 120, "residue" : "I" }, { "start" : 87, "end" : 87, "residue" : "K" }, { "start" : 149, "end" : 149, "residue" : "L" }, { "start" : 109, "end" : 109, "residue" : "K" }, { "start" : 151, "end" : 151, "residue" : "G" }, { "start" : 147, "end" : 147, "residue" : "L" }, { "start" : 84, "end" : 84, "residue" : "L" }, { "start" : 85, "end" : 85, "residue" : "T" }, { "start" : 86, "end" : 86, "residue" : "G" }, { "start" : 125, "end" : 125, "residue" : "Q" }, { "start" : 122, "end" : 122, "residue" : "A" }, { "start" : 107, "end" : 107, "residue" : "Q" }, { "start" : 108, "end" : 108, "residue" : "D" }, { "start" : 111, "end" : 111, "residue" : "G" }, { "start" : 116, "end" : 116, "residue" : "Q" }, { "start" : 146, "end" : 146, "residue" : "V" }, { "start" : 152, "end" : 152, "residue" : "G" }, { "start" : 88, "end" : 88, "residue" : "T" } ] }, { "description" : "key conserved lysine K27", "numLocations" : 1, "siteLocations" : [ { "start" : 103, "end" : 103, "residue" : "K" } ] } ], "evalue" : 1.61992E-50, "score" : 157.221, "location-fragments" : [ { "start" : 77, "end" : 152, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01803" }, { "signature" : { "accession" : "PS50053", "name" : "UBIQUITIN_2", "description" : "Ubiquitin domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000626", "name" : "Ubiquitin-like_dom", "description" : "Ubiquitin-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 153, "end" : 228, "score" : 30.735, "alignment" : "MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG", "location-fragments" : [ { "start" : 153, "end" : 228, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50053" }, { "signature" : { "accession" : "PR00348", "name" : "UBIQUITIN", "description" : "Ubiquitin signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR019956", "name" : "Ubiquitin_dom", "description" : "Ubiquitin domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 52, "pvalue" : 1.11E-15, "score" : 95.05, "motifNumber" : 2, "location-fragments" : [ { "start" : 32, "end" : 52, "dc-status" : "CONTINUOUS" } ] }, { "start" : 11, "end" : 31, "pvalue" : 4.69E-14, "score" : 82.84, "motifNumber" : 1, "location-fragments" : [ { "start" : 11, "end" : 31, "dc-status" : "CONTINUOUS" } ] }, { "start" : 53, "end" : 74, "pvalue" : 3.33E-16, "score" : 92.03, "motifNumber" : 3, "location-fragments" : [ { "start" : 53, "end" : 74, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-38, "graphscan" : "III", "model-ac" : "PR00348" }, { "signature" : { "accession" : "PS50053", "name" : "UBIQUITIN_2", "description" : "Ubiquitin domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000626", "name" : "Ubiquitin-like_dom", "description" : "Ubiquitin-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 76, "score" : 30.735, "alignment" : "MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG", "location-fragments" : [ { "start" : 1, "end" : 76, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50053" }, { "signature" : { "accession" : "PF00240", "name" : "ubiquitin", "description" : "Ubiquitin family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000626", "name" : "Ubiquitin-like_dom", "description" : "Ubiquitin-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 155, "end" : 226, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 72, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-33, "score" : 113.9, "envelopeStart" : 155, "envelopeEnd" : 226, "postProcessed" : true, "location-fragments" : [ { "start" : 155, "end" : 226, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3, "end" : 74, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 72, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-33, "score" : 113.9, "envelopeStart" : 3, "envelopeEnd" : 74, "postProcessed" : true, "location-fragments" : [ { "start" : 3, "end" : 74, "dc-status" : "CONTINUOUS" } ] }, { "start" : 79, "end" : 150, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 72, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-33, "score" : 113.9, "envelopeStart" : 79, "envelopeEnd" : 150, "postProcessed" : true, "location-fragments" : [ { "start" : 79, "end" : 150, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-102, "score" : 334.8, "model-ac" : "PF00240" }, { "signature" : { "accession" : "SSF54236", "name" : "Ubiquitin-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029071", "name" : "Ubiquitin-like_domsf", "description" : "Ubiquitin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 76, "hmmLength" : 115, "location-fragments" : [ { "start" : 1, "end" : 76, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.88E-34, "model-ac" : "0050460" }, { "signature" : { "accession" : "PS00299", "name" : "UBIQUITIN_1", "description" : "Ubiquitin domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019954", "name" : "Ubiquitin_CS", "description" : "Ubiquitin conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 103, "end" : 128, "level" : "STRONG", "cigarAlignment" : "1M2I1M1I1M3I2M3I1M1I3M1I1M4I1M", "alignment" : "KakIqDkegIPpdqQrLIFaGkqleD", "location-fragments" : [ { "start" : 103, "end" : 128, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00299" }, { "signature" : { "accession" : "G3DSA:3.10.20.90", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 153, "end" : 229, "hmmStart" : 10, "hmmEnd" : 85, "hmmLength" : 114, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.4E-45, "score" : 154.7, "envelopeStart" : 152, "envelopeEnd" : 229, "postProcessed" : true, "location-fragments" : [ { "start" : 153, "end" : 229, "dc-status" : "CONTINUOUS" } ] }, { "start" : 77, "end" : 152, "hmmStart" : 9, "hmmEnd" : 85, "hmmLength" : 114, "hmmBounds" : "INCOMPLETE", "evalue" : 1.0E-45, "score" : 155.9, "envelopeStart" : 75, "envelopeEnd" : 153, "postProcessed" : true, "location-fragments" : [ { "start" : 77, "end" : 152, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1, "end" : 76, "hmmStart" : 10, "hmmEnd" : 85, "hmmLength" : 114, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.7E-45, "score" : 154.5, "envelopeStart" : 1, "envelopeEnd" : 77, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 76, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-138, "score" : 454.4, "model-ac" : "2kdiA00" }, { "signature" : { "accession" : "SSF54236", "name" : "Ubiquitin-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029071", "name" : "Ubiquitin-like_domsf", "description" : "Ubiquitin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 152, "end" : 228, "hmmLength" : 115, "location-fragments" : [ { "start" : 152, "end" : 228, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.52E-34, "model-ac" : "0050460" }, { "signature" : { "accession" : "PS00299", "name" : "UBIQUITIN_1", "description" : "Ubiquitin domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019954", "name" : "Ubiquitin_CS", "description" : "Ubiquitin conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 27, "end" : 52, "level" : "STRONG", "cigarAlignment" : "1M2I1M1I1M3I2M3I1M1I3M1I1M4I1M", "alignment" : "KakIqDkegIPpdqQrLIFaGkqleD", "location-fragments" : [ { "start" : 27, "end" : 52, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00299" }, { "signature" : { "accession" : "PTHR10666", "name" : "UBIQUITIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 132, "hmmStart" : 77, "hmmEnd" : 208, "hmmLength" : 305, "hmmBounds" : "COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 132, "location-fragments" : [ { "start" : 1, "end" : 132, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-219, "familyName" : "", "score" : 730.3, "model-ac" : "PTHR10666" }, { "signature" : { "accession" : "SM00213", "name" : "ubq_7", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000626", "name" : "Ubiquitin-like_dom", "description" : "Ubiquitin-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 72, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 72, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-35, "score" : 134.2, "location-fragments" : [ { "start" : 1, "end" : 72, "dc-status" : "CONTINUOUS" } ] }, { "start" : 77, "end" : 148, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 72, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-35, "score" : 134.2, "location-fragments" : [ { "start" : 77, "end" : 148, "dc-status" : "CONTINUOUS" } ] }, { "start" : 153, "end" : 224, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 72, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-35, "score" : 134.2, "location-fragments" : [ { "start" : 153, "end" : 224, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-116, "score" : 402.5, "model-ac" : "SM00213" }, { "signature" : { "accession" : "PTHR10666", "name" : "UBIQUITIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 71, "end" : 164, "hmmStart" : 71, "hmmEnd" : 164, "hmmLength" : 305, "hmmBounds" : "COMPLETE", "envelopeStart" : 71, "envelopeEnd" : 164, "location-fragments" : [ { "start" : 71, "end" : 164, "dc-status" : "CONTINUOUS" } ] }, { "start" : 124, "end" : 228, "hmmStart" : 48, "hmmEnd" : 152, "hmmLength" : 305, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 124, "envelopeEnd" : 229, "location-fragments" : [ { "start" : 124, "end" : 228, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-219, "familyName" : "", "score" : 730.3, "model-ac" : "PTHR10666" }, { "signature" : { "accession" : "cd01803", "name" : "Ubl_ubiquitin", "description" : "Ubl_ubiquitin", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 76, "sites" : [ { "description" : "key conserved lysine K27", "numLocations" : 1, "siteLocations" : [ { "start" : 27, "end" : 27, "residue" : "K" } ] }, { "description" : "oligomer interface", "numLocations" : 25, "siteLocations" : [ { "start" : 68, "end" : 68, "residue" : "H" }, { "start" : 37, "end" : 37, "residue" : "P" }, { "start" : 44, "end" : 44, "residue" : "I" }, { "start" : 69, "end" : 69, "residue" : "L" }, { "start" : 6, "end" : 6, "residue" : "K" }, { "start" : 42, "end" : 42, "residue" : "R" }, { "start" : 74, "end" : 74, "residue" : "R" }, { "start" : 71, "end" : 71, "residue" : "L" }, { "start" : 36, "end" : 36, "residue" : "I" }, { "start" : 8, "end" : 8, "residue" : "L" }, { "start" : 9, "end" : 9, "residue" : "T" }, { "start" : 49, "end" : 49, "residue" : "Q" }, { "start" : 46, "end" : 46, "residue" : "A" }, { "start" : 7, "end" : 7, "residue" : "T" }, { "start" : 34, "end" : 34, "residue" : "E" }, { "start" : 70, "end" : 70, "residue" : "V" }, { "start" : 76, "end" : 76, "residue" : "G" }, { "start" : 40, "end" : 40, "residue" : "Q" }, { "start" : 11, "end" : 11, "residue" : "K" }, { "start" : 73, "end" : 73, "residue" : "L" }, { "start" : 75, "end" : 75, "residue" : "G" }, { "start" : 72, "end" : 72, "residue" : "R" }, { "start" : 48, "end" : 48, "residue" : "K" }, { "start" : 47, "end" : 47, "residue" : "G" }, { "start" : 35, "end" : 35, "residue" : "G" } ] }, { "description" : "key conserved lysines", "numLocations" : 7, "siteLocations" : [ { "start" : 63, "end" : 63, "residue" : "K" }, { "start" : 48, "end" : 48, "residue" : "K" }, { "start" : 29, "end" : 29, "residue" : "K" }, { "start" : 6, "end" : 6, "residue" : "K" }, { "start" : 11, "end" : 11, "residue" : "K" }, { "start" : 27, "end" : 27, "residue" : "K" }, { "start" : 33, "end" : 33, "residue" : "K" } ] }, { "description" : "E1 interaction site", "numLocations" : 25, "siteLocations" : [ { "start" : 68, "end" : 68, "residue" : "H" }, { "start" : 44, "end" : 44, "residue" : "I" }, { "start" : 42, "end" : 42, "residue" : "R" }, { "start" : 74, "end" : 74, "residue" : "R" }, { "start" : 71, "end" : 71, "residue" : "L" }, { "start" : 8, "end" : 8, "residue" : "L" }, { "start" : 9, "end" : 9, "residue" : "T" }, { "start" : 10, "end" : 10, "residue" : "G" }, { "start" : 49, "end" : 49, "residue" : "Q" }, { "start" : 46, "end" : 46, "residue" : "A" }, { "start" : 34, "end" : 34, "residue" : "E" }, { "start" : 70, "end" : 70, "residue" : "V" }, { "start" : 76, "end" : 76, "residue" : "G" }, { "start" : 40, "end" : 40, "residue" : "Q" }, { "start" : 12, "end" : 12, "residue" : "T" }, { "start" : 11, "end" : 11, "residue" : "K" }, { "start" : 73, "end" : 73, "residue" : "L" }, { "start" : 33, "end" : 33, "residue" : "K" }, { "start" : 75, "end" : 75, "residue" : "G" }, { "start" : 72, "end" : 72, "residue" : "R" }, { "start" : 48, "end" : 48, "residue" : "K" }, { "start" : 47, "end" : 47, "residue" : "G" }, { "start" : 31, "end" : 31, "residue" : "Q" }, { "start" : 32, "end" : 32, "residue" : "D" }, { "start" : 35, "end" : 35, "residue" : "G" } ] } ], "evalue" : 1.61992E-50, "score" : 157.221, "location-fragments" : [ { "start" : 1, "end" : 76, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01803" }, { "signature" : { "accession" : "SSF54236", "name" : "Ubiquitin-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029071", "name" : "Ubiquitin-like_domsf", "description" : "Ubiquitin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 76, "end" : 152, "hmmLength" : 115, "location-fragments" : [ { "start" : 76, "end" : 152, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.01E-34, "model-ac" : "0050460" } ], "xref" : [ { "name" : "XP_018910037.1 PREDICTED: polyubiquitin-B [Bemisia tabaci]", "id" : "XP_018910037.1" } ] },{ "sequence" : "MAAAQECGNQYSLSKKEDTSMRRSGGRGYPKLRGRGNITRGRSRSYSHHGQASYFSPNSSSFRFQNSFSSPDSDPVGTARDRLTNFDHSASNSNGFKSQNLVFSPDIDSVGAAHNRLTNSDRFATNSKGFKSQNRFFSPDSDVEDTAYSRFTNSDRSSTNSPSFRFQNGCNKKLDSSPKKFKYFPDPYNAGSNTNSDEKPNFPFKNQKFFPEPRNVCWGGDADRNLNNKKHRNFIKATGENSSTTTNANRVTNSSPTSDETPSCSCNDVSLSDLLAALNDKFSEEMNMIESLDSEVTNTWCYIKEIADVGIEDMDLSGFQKQSNFAEENNFAQPSVSRERTASDEIEVLWQEFESLESKLFQKRNGEKNSNLKSKPAKNSQDEQEILKSKPTKNSQDEQEIEGLKTTIGILTTQLQKDKNNFNTKLDKIQNQLEGRIEAINATLKKEREINKELQEKMKRGYEDMIQTIKAEYTTKLDAHKAEKEELAEQLNLQLNLTESLAKEAEDLRTQMESNKRLTLQTIKETLKDNCECSICLGICTKAVITSCGHTFCKRCLEGWQAWRNENQMCPNCRAVCTSSNIYFFNELITQLQLKFPNMDWIPSS", "md5" : "8af962b83bad53550cdb5d2cb1614d2a", "matches" : [ { "signature" : { "accession" : "cd06503", "name" : "ATP-synt_Fo_b", "description" : "ATP-synt_Fo_b", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 428, "end" : 525, "sites" : [ ], "evalue" : 6.68228E-4, "score" : 38.1875, "location-fragments" : [ { "start" : 428, "end" : 525, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd06503" }, { "signature" : { "accession" : "PS00518", "name" : "ZF_RING_1", "description" : "Zinc finger RING-type signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017907", "name" : "Znf_RING_CS", "description" : "Zinc finger, RING-type, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 548, "end" : 557, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I2M2I2M", "alignment" : "CgHtFCkrCL", "location-fragments" : [ { "start" : 548, "end" : 557, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00518" }, { "signature" : { "accession" : "SSF57850", "name" : "RING/U-box", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 516, "end" : 579, "hmmLength" : 114, "location-fragments" : [ { "start" : 516, "end" : 579, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.83E-15, "model-ac" : "0050087" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 229, "end" : 261, "location-fragments" : [ { "start" : 229, "end" : 261, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 412, "end" : 432, "location-fragments" : [ { "start" : 412, "end" : 432, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 470, "end" : 515, "location-fragments" : [ { "start" : 470, "end" : 515, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 275, "end" : 295, "location-fragments" : [ { "start" : 275, "end" : 295, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "G3DSA:3.30.40.10", "name" : "Zinc/RING finger domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013083", "name" : "Znf_RING/FYVE/PHD", "description" : "Zinc finger, RING/FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 502, "end" : 602, "hmmStart" : 11, "hmmEnd" : 99, "hmmLength" : 130, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-17, "score" : 64.5, "envelopeStart" : 502, "envelopeEnd" : 602, "postProcessed" : true, "location-fragments" : [ { "start" : 502, "end" : 602, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-17, "score" : 64.5, "model-ac" : "5dinA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 237, "end" : 261, "location-fragments" : [ { "start" : 237, "end" : 261, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF13445", "name" : "zf-RING_UBOX", "description" : "RING-type zinc-finger", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR027370", "name" : "Znf-RING_LisH", "description" : "RING-type zinc-finger, LisH dimerisation motif", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 533, "end" : 571, "hmmStart" : 1, "hmmEnd" : 40, "hmmLength" : 40, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-7, "score" : 29.9, "envelopeStart" : 533, "envelopeEnd" : 571, "postProcessed" : true, "location-fragments" : [ { "start" : 533, "end" : 571, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-7, "score" : 31.0, "model-ac" : "PF13445" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 86, "location-fragments" : [ { "start" : 1, "end" : 86, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00184", "name" : "ring_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 533, "end" : 573, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-7, "score" : 39.5, "location-fragments" : [ { "start" : 533, "end" : 573, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-7, "score" : 39.5, "model-ac" : "SM00184" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 364, "end" : 401, "location-fragments" : [ { "start" : 364, "end" : 401, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 437, "end" : 464, "location-fragments" : [ { "start" : 437, "end" : 464, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR23327", "name" : "RING FINGER PROTEIN 127", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 398, "end" : 578, "hmmStart" : 56, "hmmEnd" : 196, "hmmLength" : 446, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 233, "envelopeEnd" : 593, "location-fragments" : [ { "start" : 398, "end" : 578, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-16, "familyName" : "RING FINGER PROTEIN 127", "score" : 62.3, "model-ac" : "PTHR23327" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 40, "end" : 74, "location-fragments" : [ { "start" : 40, "end" : 74, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 378, "end" : 400, "location-fragments" : [ { "start" : 378, "end" : 400, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd16449", "name" : "RING-HC", "description" : "RING-HC", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 533, "end" : 573, "sites" : [ { "description" : "Zn binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 548, "end" : 548, "residue" : "C" }, { "start" : 556, "end" : 556, "residue" : "C" }, { "start" : 553, "end" : 553, "residue" : "C" }, { "start" : 570, "end" : 570, "residue" : "C" }, { "start" : 536, "end" : 536, "residue" : "C" }, { "start" : 533, "end" : 533, "residue" : "C" }, { "start" : 550, "end" : 550, "residue" : "H" }, { "start" : 573, "end" : 573, "residue" : "C" } ] } ], "evalue" : 1.80249E-12, "score" : 59.7885, "location-fragments" : [ { "start" : 533, "end" : 573, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd16449" }, { "signature" : { "accession" : "PS50089", "name" : "ZF_RING_2", "description" : "Zinc finger RING-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 533, "end" : 574, "score" : 13.065, "alignment" : "CSICLGICTKA--VITSCGHTFCKRCLEGWqAWRNENQMCPNCR", "location-fragments" : [ { "start" : 533, "end" : 574, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50089" } ], "xref" : [ { "name" : "XP_018910238.1 PREDICTED: E3 ubiquitin-protein ligase BRE1-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910238.1" }, { "name" : "XP_018910237.1 PREDICTED: E3 ubiquitin-protein ligase BRE1-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910237.1" } ] },{ "sequence" : "MNIDVMRCFYRATRLDTNASGYRFHLRQLFLAAYPDLTNVAEQRLVDQKRVIVNNKKLTVQEIEEIKREVAHELHIASTPIEADIIVTPSSVDEFSRHARDGVVSPRAYPIHTRPRRFVDSADSVPSFEDTMELETREKIRFFRDKWGGSNPNVRPAIPKLWMNRMCKDRIKIINNKIINELISEEADLEEIHLVVYACACTVTVLNGQKLRSHGEQCPKRRRKPAWQLRLEKKIERLRKEIGRTTHYLRGVRTKKLEKEISLIIRDKSKTVTET", "md5" : "6f8e1016219d319d21fa0872184e7b16", "matches" : [ ], "xref" : [ { "name" : "XP_018909989.1 PREDICTED: uncharacterized protein LOC109039101 [Bemisia tabaci]", "id" : "XP_018909989.1" } ] },{ "sequence" : "MSVFSPIKATFDENDRVIKVDTSEAKSVSRFGTSLLYRWGDYNFHPRAIEILCKIQKLTFKEDDVILCMFPKSGSTWLSECIYLIVNQYKYELASEESIELRFPQIDSPSHDVFDLILKRYNDSNSRRLIKSSVPPNLLIERAGSDATKPKVISIFRNPRDVLVSFYHHCKTVKHYDIEFSFDDFFETFLRGQVPCGPIWKMYNDMFKYHQANPGSTMVVFYEDMKQDLRAQLRKVCAFLNCQEPNDERAWAQLLDHLSVDRMRQNKTINRHDWDKLGLRNSNGFEFVRKGQVNDWKNFFNDEQSVRFDREITDKLLPELQARYRQQR", "md5" : "ae72cb5b906f107d9a1aa19ab1e925e6", "matches" : [ { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 318, "hmmStart" : 41, "hmmEnd" : 339, "hmmLength" : 351, "hmmBounds" : "COMPLETE", "evalue" : 7.0E-73, "score" : 247.8, "envelopeStart" : 14, "envelopeEnd" : 318, "postProcessed" : true, "location-fragments" : [ { "start" : 14, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-73, "score" : 248.2, "model-ac" : "1fmjA00" }, { "signature" : { "accession" : "PF00685", "name" : "Sulfotransfer_1", "description" : "Sulfotransferase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000863", "name" : "Sulfotransferase_dom", "description" : "Sulfotransferase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "sulfotransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008146" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 63, "end" : 314, "hmmStart" : 2, "hmmEnd" : 261, "hmmLength" : 267, "hmmBounds" : "INCOMPLETE", "evalue" : 1.1E-48, "score" : 166.1, "envelopeStart" : 62, "envelopeEnd" : 320, "postProcessed" : true, "location-fragments" : [ { "start" : 63, "end" : 314, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-49, "score" : 166.4, "model-ac" : "PF00685" }, { "signature" : { "accession" : "PTHR11783", "name" : "SULFOTRANSFERASE SULT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 44, "end" : 314, "hmmStart" : 42, "hmmEnd" : 308, "hmmLength" : 320, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 16, "envelopeEnd" : 325, "location-fragments" : [ { "start" : 44, "end" : 314, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-58, "familyName" : "GH11818P-RELATED", "score" : 200.2, "model-ac" : "PTHR11783" }, { "signature" : { "accession" : "PTHR11783:SF180", "name" : "GH11818P-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 44, "end" : 314, "hmmStart" : 42, "hmmEnd" : 308, "hmmLength" : 320, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 16, "envelopeEnd" : 325, "location-fragments" : [ { "start" : 44, "end" : 314, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-58, "familyName" : "GH11818P-RELATED", "score" : 200.2, "model-ac" : "PTHR11783:SF180" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 34, "end" : 316, "hmmLength" : 293, "location-fragments" : [ { "start" : 34, "end" : 316, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.35E-63, "model-ac" : "0051116" } ], "xref" : [ { "name" : "XP_018910025.1 PREDICTED: estrogen sulfotransferase, testis isoform-like [Bemisia tabaci]", "id" : "XP_018910025.1" } ] },{ "sequence" : "MADDSDMLNCSDSLLTNKLLQEDPDQFYTLVRMHLSFVLDLNTDDCDGPNEKTKFKPLKWNFLSKKPKGSLKGVIEKVTLTEAGMTQIAQLIEFLSKMENISQEGIFRLTGALSRQNKLKSLISQGLPLNLEDGQFSVHDCASVLKNFLSELPEPLLSDTYYPAYIQISELCTLGDSAKNRLLRSLQLLLMLLPARNRAFFKDIIKLLNLTASHEKTNKMSPENLATLFTPHLLCPRKLTPEALHMNAQKLSKVLVFMIQAGLDLFEVPPTLATDIRAYWADKNRKILSEKTGAEMVRETSAVNTVFSFVDRARTAEENTLNPTEAALAQLYAHIQSLPESSKKRRLVKQFNKENGHGTPRQFSGGKSSQKSKGFGDSIKKHILNKNGKHMVKIDYASKADKTSEDISSSECLSPNSPQHCLKSPLRENDCQNKENESDQPMKHLRFKEGAMEKIIEVSKERQSCERDTEEVNSDLTISSIDKQTEDEYFSTKSVYATTSANGAYCSSEFPERSHGHLQCPDALRTQFFSPSVRLHRKSAAKTFNFTPSGSCYALSNKFNNYTSTPACRTPSPLINDDMSPITLSAQKMTKAMQETMMTPRCRKPVIAISDSNLSNLTDLPWSPGQNSAESLKGGSKKEKNGSNRNSDTSNDSQKLGSNSDTKKDGLSNPVDFNDSHLLTDTFCDYLYSRSLLTASPVDLSFSSRTGDFEHSSSNTLSMSDGVSLMDDDDKSVIFSDEEKLSSSLLYFLDGNEPPSDSSSLSSRKRSASDSGLFSPSECLKKSPRHAAPKANCKKETSL", "md5" : "b236e27028e2bf7c5864dd317c788b4e", "matches" : [ { "signature" : { "accession" : "G3DSA:1.10.555.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR008936", "name" : "Rho_GTPase_activation_prot", "description" : "Rho GTPase activation protein", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 47, "end" : 280, "hmmStart" : 87, "hmmEnd" : 268, "hmmLength" : 271, "hmmBounds" : "COMPLETE", "evalue" : 7.7E-47, "score" : 161.5, "envelopeStart" : 47, "envelopeEnd" : 280, "postProcessed" : true, "location-fragments" : [ { "start" : 47, "end" : 280, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-47, "score" : 161.7, "model-ac" : "3eapD00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 646, "end" : 668, "location-fragments" : [ { "start" : 646, "end" : 668, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF48350", "name" : "GTPase activation domain, GAP", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR008936", "name" : "Rho_GTPase_activation_prot", "description" : "Rho GTPase activation protein", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 88, "end" : 269, "hmmLength" : 191, "location-fragments" : [ { "start" : 88, "end" : 269, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.35E-37, "model-ac" : "0037426" }, { "signature" : { "accession" : "SM00324", "name" : "RhoGAP_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 82, "end" : 263, "hmmStart" : 1, "hmmEnd" : 193, "hmmLength" : 193, "hmmBounds" : "COMPLETE", "evalue" : 3.1E-30, "score" : 116.5, "location-fragments" : [ { "start" : 82, "end" : 263, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-30, "score" : 116.5, "model-ac" : "SM00324" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 756, "end" : 776, "location-fragments" : [ { "start" : 756, "end" : 776, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 355, "end" : 373, "location-fragments" : [ { "start" : 355, "end" : 373, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR14963:SF7", "name" : "RHO GTPASE-ACTIVATING PROTEIN 19", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 764, "hmmStart" : 15, "hmmEnd" : 549, "hmmLength" : 575, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 775, "location-fragments" : [ { "start" : 10, "end" : 764, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-154, "familyName" : "RHO GTPASE-ACTIVATING PROTEIN 19", "score" : 515.8, "model-ac" : "PTHR14963:SF7" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 756, "end" : 799, "location-fragments" : [ { "start" : 756, "end" : 799, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 618, "end" : 632, "location-fragments" : [ { "start" : 618, "end" : 632, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50238", "name" : "RHOGAP", "description" : "Rho GTPase-activating proteins domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 78, "end" : 266, "score" : 33.021, "alignment" : "VTLTEA-------GMTQIAQLIEFLSKmENISQEGIFRLTGALSR-QNKLKSLISQGLPLNLEDGqfSVHDCASVLKNFLSELPEPLLSDTYYPAYIQiselcTLGDSAKNRLLRSLQLLLMLLPARNRAFFKDIIKLLNLTASHEKTNKMSPENLATLFTPHLLCPRKlTPEALHMNAQKLSKVLVFMIQAGLDLF", "location-fragments" : [ { "start" : 78, "end" : 266, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50238" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 618, "end" : 668, "location-fragments" : [ { "start" : 618, "end" : 668, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 343, "end" : 382, "location-fragments" : [ { "start" : 343, "end" : 382, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR14963", "name" : "RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 764, "hmmStart" : 15, "hmmEnd" : 549, "hmmLength" : 575, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 775, "location-fragments" : [ { "start" : 10, "end" : 764, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-154, "familyName" : "RHO GTPASE-ACTIVATING PROTEIN 19", "score" : 515.8, "model-ac" : "PTHR14963" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 783, "end" : 799, "location-fragments" : [ { "start" : 783, "end" : 799, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00620", "name" : "RhoGAP", "description" : "RhoGAP domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 88, "end" : 237, "hmmStart" : 4, "hmmEnd" : 147, "hmmLength" : 152, "hmmBounds" : "INCOMPLETE", "evalue" : 2.0E-31, "score" : 108.9, "envelopeStart" : 86, "envelopeEnd" : 242, "postProcessed" : true, "location-fragments" : [ { "start" : 88, "end" : 237, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-32, "score" : 110.5, "model-ac" : "PF00620" } ], "xref" : [ { "name" : "XP_018910553.1 PREDICTED: uncharacterized protein LOC109039509 [Bemisia tabaci]", "id" : "XP_018910553.1" } ] },{ "sequence" : "MLELTWTILLSVGLIHQTSGSDYLAELLKKHPTWSFELENVESFIQRTLAYLGSSDVDTEDMLRARVSESIPLDMDHIPRKIDDPKWVSPQELPDRYDARQKWKSCSNLLRDVQDEGVCHTDSPGIVSSVMADRYCIFTNGSFKEVLSQEMLVGCAEYCTQGSRLAQSWRYATSEGIPTGGGFNSRKGCLPYDHPPCRHTNGSYVHSPVEGGRRLKPCDESFPYDHDCPKQCTNRKYSKSLDADRVKLETWYMLSRDESDIRRDIFAYGPVATFIIFTDQLFDKPDGMYQQKEGRRRISTFKCLKLIGWGEESNVKFWLAVNSWDSWGNKVFKIPRGSNYDLVESLPTTGIYFK", "md5" : "f17019cd5c3e29ebc70514df014fbb28", "matches" : [ { "signature" : { "accession" : "PTHR12411", "name" : "CYSTEINE PROTEASE FAMILY C1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 63, "end" : 340, "hmmStart" : 70, "hmmEnd" : 337, "hmmLength" : 351, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 19, "envelopeEnd" : 352, "location-fragments" : [ { "start" : 63, "end" : 340, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-35, "familyName" : "", "score" : 124.4, "model-ac" : "PTHR12411" }, { "signature" : { "accession" : "PF00112", "name" : "Peptidase_C1", "description" : "Papain family cysteine protease", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 93, "end" : 339, "hmmStart" : 1, "hmmEnd" : 205, "hmmLength" : 218, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.2E-19, "score" : 69.0, "envelopeStart" : 93, "envelopeEnd" : 350, "postProcessed" : true, "location-fragments" : [ { "start" : 93, "end" : 339, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-19, "score" : 70.0, "model-ac" : "PF00112" }, { "signature" : { "accession" : "G3DSA:3.90.70.10", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 77, "end" : 352, "hmmStart" : 30, "hmmEnd" : 282, "hmmLength" : 285, "hmmBounds" : "COMPLETE", "evalue" : 8.7E-51, "score" : 175.2, "envelopeStart" : 77, "envelopeEnd" : 352, "postProcessed" : true, "location-fragments" : [ { "start" : 77, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-51, "score" : 175.6, "model-ac" : "4i05A00" }, { "signature" : { "accession" : "SM00645", "name" : "pept_c1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 93, "end" : 351, "hmmStart" : 1, "hmmEnd" : 340, "hmmLength" : 340, "hmmBounds" : "COMPLETE", "evalue" : 7.2E-9, "score" : 30.2, "location-fragments" : [ { "start" : 93, "end" : 351, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.2E-9, "score" : 30.2, "model-ac" : "SM00645" }, { "signature" : { "accession" : "SSF54001", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038765", "name" : "Papain-like_cys_pep_sf", "description" : "Papain-like cysteine peptidase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 87, "end" : 351, "hmmLength" : 313, "location-fragments" : [ { "start" : 87, "end" : 351, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.37E-33, "model-ac" : "0040950" }, { "signature" : { "accession" : "PTHR12411:SF606", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 63, "end" : 340, "hmmStart" : 70, "hmmEnd" : 337, "hmmLength" : 351, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 19, "envelopeEnd" : 352, "location-fragments" : [ { "start" : 63, "end" : 340, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-35, "familyName" : "", "score" : 124.4, "model-ac" : "PTHR12411:SF606" } ], "xref" : [ { "name" : "XP_018909852.1 PREDICTED: cathepsin B-like [Bemisia tabaci]", "id" : "XP_018909852.1" } ] },{ "sequence" : "MSNKVGYQPVWTEDEEAALNSVVVTEGLQVPRPRTTMPQISVDSVQGRMDRRQQRLNTELLDASIKGLLPAVKRALDEGANVNTVCRDSGVSASHIAAHLGHTAILQHLLSAGAKPKSDFKGRHPIHLAAWRGHLSVLEILVKGDVDVKVEPPKCEDLQATSLDSWDHNHCSINQTMSAMQLGATALHVASQRAKCYCVKFLFKAGASTTARDARDLTPMDVVGELSGPEEREYCSRDQWARVPLGDDSDDDAAPRLLRSTHHFVQSRGIPSDDEAARSYLSDSRSRRGSHIDLEDPPEETNDMMRNIINMFIMSGAQLDGETNEELETFLKSKKMTPLHTAVLKGNLSVVRILLENDFDATILNEDGLAPIHLAVQEGSLEVLKILLSGEGRRQRLINLKNAKGLTPLHMAVLQEWASGVSLLLEAGADLVVTTSHDANTVLHLAAQKGNAKLINELLTVVEAKAIIDAKNKTHHTALMISVISGDTDSVEALLNHNADTLVTLPSNVTVLHLATQQGSSAVLEFLLSQDEHKSKSLVNTRETITGTTPLHAAALRGYTDCVRCLLQHEADVYAKASDVPYFGGTALHLASRKGHASVVKALVEHDKNLVGCYNTNRWYPLHIAARFGHRNCVKEIIIGGGNLAEMVKDNEGTDRTAIEILLWCLPQPVKLVNQLLDSAITVNGYPLNHARCIVKLHYDILCPGTTGGRQMRVLTSILNAGDKPLKESALPHPLVETFLHFKWKKLCGIFLCFALVNTLFTVSLTARSMLLHLHRSPEAQKGFFAAAVADAVCQFFLFLTFPAIIVKELLHASQQEKYYWSDFESWLKWSVLALTALTLASSDLGWGYEEAQKHANSFAVLLAWIHLLVLLSRLPSWGLHVLMFFSVARNFIKVFCAFSILILGFTFAFLIQFEGSAPFTDFWASLMKVVVMTSEFDYGSMFEEDSRADPVVGRLIFILFIVLVAVVLMNLLVGLAVSDITVLEAQGKSERLSKQVDFLSLIEGFVFNEAILKFVPERLQKWIQRKIAVPSFLKVYPGRPLDESLPRPLKESVLETLRTTGSKNASVNDACTTRSYESESDLGEGSDDEDVKNLISEVMTELRDIKKQIEILKR", "md5" : "f0dce7e190940e79d220e0509cbe61c8", "matches" : [ { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 182, "end" : 214, "score" : 10.446, "alignment" : "LGATALHVASQRAKCYCVKFLFKAGASTTARDA", "location-fragments" : [ { "start" : 182, "end" : 214, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 121, "end" : 153, "score" : 10.499, "alignment" : "KGRHPIHLAAWRGHLSVLEILVKGDVDVKVEPP", "location-fragments" : [ { "start" : 121, "end" : 153, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 367, "end" : 389, "score" : 10.018, "alignment" : "DGLAPIHLAVQEGSLEVLKILLS----------", "location-fragments" : [ { "start" : 367, "end" : 389, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1100, "end" : 1115, "location-fragments" : [ { "start" : 1100, "end" : 1115, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "G3DSA:1.25.40.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 39, "end" : 230, "hmmStart" : 27, "hmmEnd" : 171, "hmmLength" : 329, "hmmBounds" : "COMPLETE", "evalue" : 9.1E-30, "score" : 105.9, "envelopeStart" : 39, "envelopeEnd" : 230, "postProcessed" : true, "location-fragments" : [ { "start" : 39, "end" : 230, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-138, "score" : 462.8, "model-ac" : "4rlyA00" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 334, "end" : 366, "score" : 11.594, "alignment" : "KKMTPLHTAVLKGNLSVVRILLENDFDATILNE", "location-fragments" : [ { "start" : 334, "end" : 366, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "PS50297", "name" : "ANK_REP_REGION", "description" : "Ankyrin repeat region circular profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR020683", "name" : "Ankyrin_rpt-contain_dom", "description" : "Ankyrin repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 55, "end" : 649, "score" : 70.724, "alignment" : "RLNTELLDASIKGLLPAVKRALDEGANVNTVCRdSGVSASHIAAHLGHTAILQHLLSAGAKPKS-DFKGRHPIHLAAWRGHLSVLEILVKGDVDVKVEPPkcedlqatsldswdhnhcsinqtmsamqLGATALHVASQRAKCYCVKFLFKAGASTTARDARDLTPMDVVGELSGPEereycsrdqWARVPLGDDSDDDAAPRLLRSTHHFVQSRGIPSDDEAARSYLSDSRSRRGSHIDLEDPPEETNDMMrnIINMFIMSGAQLDGETNeeletflksKKMTPLHTAVLKGNLSVVRILLENDFDATILNEDGLAPIHLAVQEGSLEVLKILLSGEGRRQRLINlknaKGLTPLHMAVLQEWASGVSLLLEAGADLVVTTShDANTVLHLAAQKGNAKlinELLTVVEAKAIIDAKNKTHHTALMISVISGDTDSVEALLNHNADTLVTLPSNVTVLHLATQQGSSAVLEFLLSQDEHKSKSLVntretiTGTTPLHAAALRGYTDCVRCLLQHEADVYAKASdvpyFGGTALHLASRKGHASVVKALVEHDKNLVGCYNtNRWYPLHIAARFGHRNCVKEIIIGGGNLAEMVK", "location-fragments" : [ { "start" : 55, "end" : 649, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50297" }, { "signature" : { "accession" : "PF00520", "name" : "Ion_trans", "description" : "Ion transport protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005821", "name" : "Ion_trans_dom", "description" : "Ion transport domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 779, "end" : 982, "hmmStart" : 28, "hmmEnd" : 238, "hmmLength" : 245, "hmmBounds" : "INCOMPLETE", "evalue" : 2.0E-12, "score" : 46.9, "envelopeStart" : 749, "envelopeEnd" : 989, "postProcessed" : true, "location-fragments" : [ { "start" : 779, "end" : 982, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-12, "score" : 47.6, "model-ac" : "PF00520" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 245, "end" : 269, "location-fragments" : [ { "start" : 245, "end" : 269, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF48403", "name" : "Ankyrin repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 332, "end" : 643, "hmmLength" : 408, "location-fragments" : [ { "start" : 332, "end" : 643, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.54E-52, "model-ac" : "0048259" }, { "signature" : { "accession" : "PTHR24178", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 546, "end" : 660, "hmmStart" : 450, "hmmEnd" : 584, "hmmLength" : 786, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 542, "envelopeEnd" : 691, "location-fragments" : [ { "start" : 546, "end" : 660, "dc-status" : "CONTINUOUS" } ] }, { "start" : 333, "end" : 573, "hmmStart" : 344, "hmmEnd" : 572, "hmmLength" : 786, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 306, "envelopeEnd" : 580, "location-fragments" : [ { "start" : 333, "end" : 573, "dc-status" : "CONTINUOUS" } ] }, { "start" : 54, "end" : 393, "hmmStart" : 268, "hmmEnd" : 507, "hmmLength" : 786, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 46, "envelopeEnd" : 396, "location-fragments" : [ { "start" : 54, "end" : 393, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-98, "familyName" : "FAMILY NOT NAMED", "score" : 332.5, "model-ac" : "PTHR24178" }, { "signature" : { "accession" : "SSF48403", "name" : "Ankyrin repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 56, "end" : 222, "hmmLength" : 277, "location-fragments" : [ { "start" : 56, "end" : 222, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-23, "model-ac" : "0053922" }, { "signature" : { "accession" : "PF12796", "name" : "Ank_2", "description" : "Ankyrin repeats (3 copies)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR020683", "name" : "Ankyrin_rpt-contain_dom", "description" : "Ankyrin repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 508, "end" : 576, "hmmStart" : 26, "hmmEnd" : 82, "hmmLength" : 83, "hmmBounds" : "INCOMPLETE", "evalue" : 6.8E-10, "score" : 39.4, "envelopeStart" : 502, "envelopeEnd" : 577, "postProcessed" : true, "location-fragments" : [ { "start" : 508, "end" : 576, "dc-status" : "CONTINUOUS" } ] }, { "start" : 583, "end" : 638, "hmmStart" : 25, "hmmEnd" : 73, "hmmLength" : 83, "hmmBounds" : "INCOMPLETE", "evalue" : 4.6E-10, "score" : 40.0, "envelopeStart" : 575, "envelopeEnd" : 647, "postProcessed" : true, "location-fragments" : [ { "start" : 583, "end" : 638, "dc-status" : "CONTINUOUS" } ] }, { "start" : 438, "end" : 501, "hmmStart" : 21, "hmmEnd" : 79, "hmmLength" : 83, "hmmBounds" : "INCOMPLETE", "evalue" : 1.1E-6, "score" : 29.2, "envelopeStart" : 433, "envelopeEnd" : 504, "postProcessed" : true, "location-fragments" : [ { "start" : 438, "end" : 501, "dc-status" : "CONTINUOUS" } ] }, { "start" : 63, "end" : 148, "hmmStart" : 4, "hmmEnd" : 79, "hmmLength" : 83, "hmmBounds" : "INCOMPLETE", "evalue" : 1.1E-8, "score" : 35.5, "envelopeStart" : 60, "envelopeEnd" : 151, "postProcessed" : true, "location-fragments" : [ { "start" : 63, "end" : 148, "dc-status" : "CONTINUOUS" } ] }, { "start" : 339, "end" : 434, "hmmStart" : 1, "hmmEnd" : 82, "hmmLength" : 83, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.4E-13, "score" : 49.6, "envelopeStart" : 339, "envelopeEnd" : 435, "postProcessed" : true, "location-fragments" : [ { "start" : 339, "end" : 434, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-60, "score" : 201.9, "model-ac" : "PF12796" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 89, "end" : 121, "score" : 8.736, "alignment" : "SGVSASHIAAHLGHTAILQHLLSAGAKPKSDFK", "location-fragments" : [ { "start" : 89, "end" : 121, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "G3DSA:1.25.40.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 505, "end" : 578, "hmmStart" : 52, "hmmEnd" : 126, "hmmLength" : 158, "hmmBounds" : "INCOMPLETE", "evalue" : 7.7E-15, "score" : 56.7, "envelopeStart" : 502, "envelopeEnd" : 580, "postProcessed" : true, "location-fragments" : [ { "start" : 505, "end" : 578, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.7E-79, "score" : 265.7, "model-ac" : "4bszB00" }, { "signature" : { "accession" : "SM00248", "name" : "ANK_2a", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 546, "end" : 575, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 4.8E-5, "score" : 32.8, "location-fragments" : [ { "start" : 546, "end" : 575, "dc-status" : "CONTINUOUS" } ] }, { "start" : 89, "end" : 118, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 34.0, "score" : 13.3, "location-fragments" : [ { "start" : 89, "end" : 118, "dc-status" : "CONTINUOUS" } ] }, { "start" : 182, "end" : 211, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 1.4, "score" : 17.9, "location-fragments" : [ { "start" : 182, "end" : 211, "dc-status" : "CONTINUOUS" } ] }, { "start" : 121, "end" : 150, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 0.0028, "score" : 26.9, "location-fragments" : [ { "start" : 121, "end" : 150, "dc-status" : "CONTINUOUS" } ] }, { "start" : 334, "end" : 363, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 0.0016, "score" : 27.7, "location-fragments" : [ { "start" : 334, "end" : 363, "dc-status" : "CONTINUOUS" } ] }, { "start" : 404, "end" : 433, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 7.3, "score" : 15.5, "location-fragments" : [ { "start" : 404, "end" : 433, "dc-status" : "CONTINUOUS" } ] }, { "start" : 617, "end" : 646, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 0.011, "score" : 24.9, "location-fragments" : [ { "start" : 617, "end" : 646, "dc-status" : "CONTINUOUS" } ] }, { "start" : 367, "end" : 400, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 2.6, "score" : 17.0, "location-fragments" : [ { "start" : 367, "end" : 400, "dc-status" : "CONTINUOUS" } ] }, { "start" : 55, "end" : 84, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 610.0, "score" : 6.6, "location-fragments" : [ { "start" : 55, "end" : 84, "dc-status" : "CONTINUOUS" } ] }, { "start" : 438, "end" : 467, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 37.0, "score" : 13.2, "location-fragments" : [ { "start" : 438, "end" : 467, "dc-status" : "CONTINUOUS" } ] }, { "start" : 474, "end" : 503, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 0.49, "score" : 19.4, "location-fragments" : [ { "start" : 474, "end" : 503, "dc-status" : "CONTINUOUS" } ] }, { "start" : 507, "end" : 536, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 300.0, "score" : 8.9, "location-fragments" : [ { "start" : 507, "end" : 536, "dc-status" : "CONTINUOUS" } ] }, { "start" : 583, "end" : 612, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 0.03, "score" : 23.5, "location-fragments" : [ { "start" : 583, "end" : 612, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.1E-70, "score" : 247.8, "model-ac" : "SM00248" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 583, "end" : 610, "score" : 9.938, "alignment" : "FGGTALHLASRKGHASVVKALVEHDKNL-----", "location-fragments" : [ { "start" : 583, "end" : 610, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 546, "end" : 578, "score" : 11.995, "alignment" : "TGTTPLHAAALRGYTDCVRCLLQHEADVYAKAS", "location-fragments" : [ { "start" : 546, "end" : 578, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "G3DSA:1.25.40.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 579, "end" : 665, "hmmStart" : 37, "hmmEnd" : 103, "hmmLength" : 137, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.0E-13, "score" : 51.5, "envelopeStart" : 577, "envelopeEnd" : 665, "postProcessed" : true, "location-fragments" : [ { "start" : 579, "end" : 665, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-83, "score" : 278.5, "model-ac" : "1s70B02" }, { "signature" : { "accession" : "G3DSA:1.25.40.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 299, "end" : 504, "hmmStart" : 22, "hmmEnd" : 209, "hmmLength" : 241, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.3E-41, "score" : 142.2, "envelopeStart" : 299, "envelopeEnd" : 506, "postProcessed" : true, "location-fragments" : [ { "start" : 299, "end" : 504, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.1E-97, "score" : 325.5, "model-ac" : "1k1aA00" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 404, "end" : 436, "score" : 11.087, "alignment" : "KGLTPLHMAVLQEWASGVSLLLEAGADLVVTTS", "location-fragments" : [ { "start" : 404, "end" : 436, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" } ], "xref" : [ { "name" : "XP_018909828.1 PREDICTED: transient receptor potential channel pyrexia-like [Bemisia tabaci]", "id" : "XP_018909828.1" } ] },{ "sequence" : "MKEAVGRVIYLLVFLVPGTLPIPACRISEFPCRNGRCIRLDQYCNGIADCPDKSDEPRYCTVCNRTYYGDIPTTYSLSLPRPKDEKLPFLCHLTFTANGRENGELVQLMFESFELGRYEAASPEGCPDGHMQLSELGRPFTGGFWCGAASAPAVYFTETSTVTITLRLFQPPSGTQAPPFSFRLRYKFVGDEAAVVRFGTLAAPLERGDIVPGTYCSRNFYECYFKRCRIQSPNYPGIYPRNVTCYLTIRQKKVPTCKHAMISVRQDNGHKMQIRSLREGASASATGGTSGVQAGTNRTERRLRVWEDCTSERDHLMFYDGASTDDPLLVKYCGGDWLPKIVSRGPVMLVTFHSSPYSVPLSPPGATSPLRGFELDVDILFSDSDSLDFARQSRSCEFLVNASHPDSDDAMQRSRGREGFVLSPRHTLPANSTCVYRFRGSEADLVWLYFVSYAHHPLRQRNASHVAVPERESCATRLRIWDGGGSVLGDHCDAPKLCDHATLANATRRGRPCSIEESYVSFSNSIVIQHKSTPGTALHPASFRLRYEFVDTRLGGEPYFGRKDDDVPTTTCSRLFRKMRSGQIHTPKNVFLYGRGGTANLSCYYRIEAGPGERVQLTIRNVSFGERAECYTEADPHTGRYVCARSPERAARKNYELLVTEAPWRDVRTAKACICNNATSAAAQQALNTLQALTFTSATKVLELTFKIFNMNMTEDYKDVYFYAEFEMVRAADCARKQRLRGSGGEIEFANPPQSRADKQCFGAPWFIEANENKSLFLMTWGHLLPLHPAPDEPVKCHTRNRILLYYGTTKRLSHVICPALHSSRQSELHIFSEEWFGYQEEDETHGGGPLQNPRTPNFLLEFVAREPGGATVNWLEVSRPKSSFLKQLHPSSELIEEQTIGVVGPVVGGNTTDPGCPHKCHDLNACISAVLWCDGVRNCPDGSDENPAVCGVSRLIFTLLPTYAILGGGVASSAACFVVLCFLALHRSHQRKRRLLGADKMGASQRAPTEEFLVNSQGSLASS", "md5" : "4882edf7ada9421929dca8ad4b2f4f2e", "matches" : [ { "signature" : { "accession" : "G3DSA:2.60.120.290", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR035914", "name" : "Sperma_CUB_dom_sf", "description" : "Spermadhesin, CUB domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 216, "end" : 380, "hmmStart" : 9, "hmmEnd" : 117, "hmmLength" : 124, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-15, "score" : 59.6, "envelopeStart" : 216, "envelopeEnd" : 380, "postProcessed" : true, "location-fragments" : [ { "start" : 216, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-34, "score" : 119.2, "model-ac" : "4gz9A02" }, { "signature" : { "accession" : "G3DSA:4.10.400.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036055", "name" : "LDL_receptor-like_sf", "description" : "LDL receptor-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 23, "end" : 56, "hmmStart" : 10, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-10, "score" : 42.3, "envelopeStart" : 23, "envelopeEnd" : 56, "postProcessed" : true, "location-fragments" : [ { "start" : 23, "end" : 56, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-17, "score" : 63.0, "model-ac" : "1xfeA01" }, { "signature" : { "accession" : "SSF57424", "name" : "LDL receptor-like module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036055", "name" : "LDL_receptor-like_sf", "description" : "LDL receptor-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 919, "end" : 952, "hmmLength" : 50, "location-fragments" : [ { "start" : 919, "end" : 952, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.83E-6, "model-ac" : "0041241" }, { "signature" : { "accession" : "cd00041", "name" : "CUB", "description" : "CUB", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000859", "name" : "CUB_dom", "description" : "CUB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 229, "end" : 354, "sites" : [ ], "evalue" : 8.13997E-13, "score" : 63.9706, "location-fragments" : [ { "start" : 229, "end" : 354, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00041" }, { "signature" : { "accession" : "PS50068", "name" : "LDLRA_2", "description" : "LDL-receptor class A (LDLRA) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 24, "end" : 61, "score" : 12.35, "alignment" : "ACRISEFPCRNGRCIRLDQYCNGIADCPDKSDEpRYCT", "location-fragments" : [ { "start" : 24, "end" : 61, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50068" }, { "signature" : { "accession" : "PTHR47537:SF3", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 997, "hmmStart" : 5, "hmmEnd" : 921, "hmmLength" : 949, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 20, "envelopeEnd" : 1021, "location-fragments" : [ { "start" : 35, "end" : 997, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "", "score" : 1049.6, "model-ac" : "PTHR47537:SF3" }, { "signature" : { "accession" : "SSF49854", "name" : "Spermadhesin, CUB domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035914", "name" : "Sperma_CUB_dom_sf", "description" : "Spermadhesin, CUB domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 416, "end" : 551, "hmmLength" : 117, "location-fragments" : [ { "start" : 416, "end" : 551, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.44E-5, "model-ac" : "0041645" }, { "signature" : { "accession" : "PF00057", "name" : "Ldl_recept_a", "description" : "Low-density lipoprotein receptor domain class A", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 24, "end" : 60, "hmmStart" : 2, "hmmEnd" : 37, "hmmLength" : 37, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.3E-10, "score" : 38.9, "envelopeStart" : 23, "envelopeEnd" : 60, "postProcessed" : true, "location-fragments" : [ { "start" : 24, "end" : 60, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-12, "score" : 47.3, "model-ac" : "PF00057" }, { "signature" : { "accession" : "SSF49854", "name" : "Spermadhesin, CUB domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035914", "name" : "Sperma_CUB_dom_sf", "description" : "Spermadhesin, CUB domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 230, "end" : 357, "hmmLength" : 108, "location-fragments" : [ { "start" : 230, "end" : 272, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 306, "end" : 357, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.57E-13, "model-ac" : "0054622" }, { "signature" : { "accession" : "PTHR47537", "name" : "CUBILIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 997, "hmmStart" : 5, "hmmEnd" : 921, "hmmLength" : 949, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 20, "envelopeEnd" : 1021, "location-fragments" : [ { "start" : 35, "end" : 997, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "", "score" : 1049.6, "model-ac" : "PTHR47537" }, { "signature" : { "accession" : "cd00112", "name" : "LDLa", "description" : "LDLa", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 919, "end" : 947, "sites" : [ { "description" : "calcium-binding site", "numLocations" : 5, "siteLocations" : [ { "start" : 945, "end" : 945, "residue" : "D" }, { "start" : 939, "end" : 939, "residue" : "N" }, { "start" : 946, "end" : 946, "residue" : "E" }, { "start" : 935, "end" : 935, "residue" : "D" }, { "start" : 932, "end" : 932, "residue" : "L" } ] }, { "description" : "D-X-S-D-E motif", "numLocations" : 5, "siteLocations" : [ { "start" : 942, "end" : 942, "residue" : "D" }, { "start" : 943, "end" : 943, "residue" : "G" }, { "start" : 945, "end" : 945, "residue" : "D" }, { "start" : 946, "end" : 946, "residue" : "E" }, { "start" : 944, "end" : 944, "residue" : "S" } ] }, { "description" : "putative binding surface", "numLocations" : 4, "siteLocations" : [ { "start" : 919, "end" : 919, "residue" : "H" }, { "start" : 940, "end" : 940, "residue" : "C" }, { "start" : 939, "end" : 939, "residue" : "N" }, { "start" : 928, "end" : 928, "residue" : "I" } ] } ], "evalue" : 1.07718E-5, "score" : 41.0382, "location-fragments" : [ { "start" : 919, "end" : 947, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00112" }, { "signature" : { "accession" : "G3DSA:2.40.128.620", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 917, "end" : 960, "hmmStart" : 8, "hmmEnd" : 44, "hmmLength" : 166, "hmmBounds" : "COMPLETE", "evalue" : 6.7E-8, "score" : 34.8, "envelopeStart" : 917, "envelopeEnd" : 960, "postProcessed" : true, "location-fragments" : [ { "start" : 917, "end" : 960, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.3E-16, "score" : 60.7, "model-ac" : "2gtlM02" }, { "signature" : { "accession" : "cd00112", "name" : "LDLa", "description" : "LDLa", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 25, "end" : 56, "sites" : [ { "description" : "D-X-S-D-E motif", "numLocations" : 5, "siteLocations" : [ { "start" : 54, "end" : 54, "residue" : "S" }, { "start" : 52, "end" : 52, "residue" : "D" }, { "start" : 53, "end" : 53, "residue" : "K" }, { "start" : 55, "end" : 55, "residue" : "D" }, { "start" : 56, "end" : 56, "residue" : "E" } ] }, { "description" : "putative binding surface", "numLocations" : 4, "siteLocations" : [ { "start" : 30, "end" : 30, "residue" : "F" }, { "start" : 49, "end" : 49, "residue" : "D" }, { "start" : 50, "end" : 50, "residue" : "C" }, { "start" : 38, "end" : 38, "residue" : "I" } ] }, { "description" : "calcium-binding site", "numLocations" : 5, "siteLocations" : [ { "start" : 45, "end" : 45, "residue" : "N" }, { "start" : 49, "end" : 49, "residue" : "D" }, { "start" : 55, "end" : 55, "residue" : "D" }, { "start" : 42, "end" : 42, "residue" : "Q" }, { "start" : 56, "end" : 56, "residue" : "E" } ] } ], "evalue" : 2.8997E-10, "score" : 54.135, "location-fragments" : [ { "start" : 25, "end" : 56, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00112" }, { "signature" : { "accession" : "PS01180", "name" : "CUB", "description" : "CUB domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000859", "name" : "CUB_dom", "description" : "CUB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 63, "end" : 189, "score" : 9.097, "alignment" : "CNRTYYGDIPTTYSLSLPR---PKDeklpFLCHLTFTANGRENgELVQLMFES-FELGRYEAaspegCPDGHMQLSELgrpFTGGFWCGAASAPAVyfTETSTVTITLRLFQPPSGTQappFSFRLRYKFV", "location-fragments" : [ { "start" : 63, "end" : 189, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01180" }, { "signature" : { "accession" : "PR00261", "name" : "LDLRECEPTOR", "description" : "Low density lipoprotein (LDL) receptor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 925, "end" : 946, "pvalue" : 1.14E-6, "score" : 45.12, "motifNumber" : 6, "location-fragments" : [ { "start" : 925, "end" : 946, "dc-status" : "CONTINUOUS" } ] }, { "start" : 35, "end" : 56, "pvalue" : 1.99E-7, "score" : 48.0, "motifNumber" : 1, "location-fragments" : [ { "start" : 35, "end" : 56, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-7, "graphscan" : "I....I", "model-ac" : "PR00261" }, { "signature" : { "accession" : "SM00192", "name" : "LDLa_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 916, "end" : 953, "hmmStart" : 1, "hmmEnd" : 47, "hmmLength" : 47, "hmmBounds" : "COMPLETE", "evalue" : 5.3E-7, "score" : 39.3, "location-fragments" : [ { "start" : 916, "end" : 953, "dc-status" : "CONTINUOUS" } ] }, { "start" : 24, "end" : 62, "hmmStart" : 1, "hmmEnd" : 47, "hmmLength" : 47, "hmmBounds" : "COMPLETE", "evalue" : 7.4E-12, "score" : 55.4, "location-fragments" : [ { "start" : 24, "end" : 62, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-23, "score" : 94.6, "model-ac" : "SM00192" }, { "signature" : { "accession" : "PS01209", "name" : "LDLRA_1", "description" : "LDL-receptor class A (LDLRA) domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR023415", "name" : "LDLR_class-A_CS", "description" : "Low-density lipoprotein (LDL) receptor class A, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 60, "level" : "STRONG", "cigarAlignment" : "2M5I2M3I2M3I3M3I1M", "alignment" : "CIrldqyCNgiaDCpdkSDEpryC", "location-fragments" : [ { "start" : 37, "end" : 60, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01209" }, { "signature" : { "accession" : "PS50068", "name" : "LDLRA_2", "description" : "LDL-receptor class A (LDLRA) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002172", "name" : "LDrepeatLR_classA_rpt", "description" : "Low-density lipoprotein (LDL) receptor class A repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 920, "end" : 952, "score" : 9.2, "alignment" : "-------KCHDlNACISAVLWCDGVRNCPDGSDEnpAVCG", "location-fragments" : [ { "start" : 920, "end" : 952, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50068" }, { "signature" : { "accession" : "SSF57424", "name" : "LDL receptor-like module", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036055", "name" : "LDL_receptor-like_sf", "description" : "LDL receptor-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 21, "end" : 58, "hmmLength" : 47, "location-fragments" : [ { "start" : 21, "end" : 58, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.02E-10, "model-ac" : "0039720" }, { "signature" : { "accession" : "SM00042", "name" : "CUB_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000859", "name" : "CUB_dom", "description" : "CUB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 216, "end" : 380, "hmmStart" : 1, "hmmEnd" : 144, "hmmLength" : 144, "hmmBounds" : "COMPLETE", "evalue" : 3.1E-4, "score" : 30.0, "location-fragments" : [ { "start" : 216, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-4, "score" : 30.0, "model-ac" : "SM00042" }, { "signature" : { "accession" : "PS01180", "name" : "CUB", "description" : "CUB domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000859", "name" : "CUB_dom", "description" : "CUB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 216, "end" : 380, "score" : 10.68, "alignment" : "CSRNFYECyfkRCRIQSPNYPGI-YPRNVTCYLTIRQKKVptcKHAMISVRQDNGHKMQIRSLregasasatggtsgvqagtnrterrlrvwedctSERDHLMFYDGastddPLLVKYCGGDWLPK-IVSRGPVMLVTFHSSPySVPLsppgatsplRGFELDVDIL", "location-fragments" : [ { "start" : 216, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01180" } ], "xref" : [ { "name" : "XP_018909717.1 PREDICTED: uncharacterized protein LOC109038906 [Bemisia tabaci]", "id" : "XP_018909717.1" } ] },{ "sequence" : "MTLKLDDFLTKKKEPAQILDLSKATANSKEELRRLIEKIPEYKIKPEKVKPDEIKIREKDFSFKITKKELKPKREYAFQDPTPPEMREIKLEDLSSVNIPWKMLTSLRPKTKLDEEFYSRLVELGKLALKTRAREKRIQDSDFVRKMKNRAGIVETRILSCKECYEEFCTGEACCDFLYESYQRENRGPVAVDESGQPVEKQDGRARGRAKKKRRLKKKPKPRAKSTKSLDRGKTKLKRDSPQRRSKSLDKQRFLKDSHDSSQEARGKSESKRKSNASKSKKGKSPGERQKKTSKTFKKKVTMNIGSGKGV", "md5" : "6c8e0251c76a97b3b640e294854a1a14", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 226, "end" : 292, "location-fragments" : [ { "start" : 226, "end" : 292, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 207, "end" : 225, "location-fragments" : [ { "start" : 207, "end" : 225, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 189, "end" : 311, "location-fragments" : [ { "start" : 189, "end" : 311, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909565.1 PREDICTED: uncharacterized protein LOC109038820 [Bemisia tabaci]", "id" : "XP_018909565.1" } ] },{ "sequence" : "MAKTSLSSSSLFSNPDALFYLLIPTIILWFVYFRMSRKRLYELAAQIQGPEGYPLAGSIHEFVGDPMKIFQKMWKLSHKYTKNGSPGKLWIGHRLIVFLSHPKDIEVIYGSQTHIYKSPEYGFFNSWLRSGILINNGEKWRALRKLIAPSFHLNVLRSFVDHFYKHSLSVVHKMKEEGSKEFDVHHYMGACTTEILLETAMGVDKKTHQVNGFEYASAVMKLCEILHLRQVKLWLRPDSAFKLTSYASEHNRLLKYIDELPQKVTKKKRADFLKKKQTTVEKCNTKSEEVKEAERGAQRLDAKRNKGEVTETVEGVSYGQSAGLKDDLDDDIGEKKRQPFLESLIENAANGANLTDEDIRDQINTIMFAGHDTTAAGSSFFLCMMGVRPDIQEKVVEELEQIFGDSDRPCTFEDTLEMKYMERCIMETLRLYPPVPMTGREPQEEIKLKSTDLTVPAKCTIVIGIFKLHRDPSIYPNPDEFNPDNFLPEKTTNRHYYAFVPFGAGPRGCLGRKFAMLQLKVLLSTVLRNYKIYSDVPQKDWKLQADIILKRADGFRIRLEPRKMTPKPKN", "md5" : "1180036aff35322c5abca8f0e0c059ec", "matches" : [ { "signature" : { "accession" : "PF00067", "name" : "p450", "description" : "Cytochrome P450", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001128", "name" : "Cyt_P450", "description" : "Cytochrome P450", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 48, "end" : 535, "hmmStart" : 2, "hmmEnd" : 438, "hmmLength" : 463, "hmmBounds" : "INCOMPLETE", "evalue" : 6.1E-92, "score" : 308.8, "envelopeStart" : 47, "envelopeEnd" : 557, "postProcessed" : true, "location-fragments" : [ { "start" : 48, "end" : 535, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-93, "score" : 314.2, "model-ac" : "PF00067" }, { "signature" : { "accession" : "SSF48264", "name" : "Cytochrome P450", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036396", "name" : "Cyt_P450_sf", "description" : "Cytochrome P450 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 49, "end" : 562, "hmmLength" : 463, "location-fragments" : [ { "start" : 49, "end" : 272, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 333, "end" : 562, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.31E-103, "model-ac" : "0054912" }, { "signature" : { "accession" : "PTHR24291:SF106", "name" : "CYTOCHROME P450 4G1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 562, "hmmStart" : 23, "hmmEnd" : 560, "hmmLength" : 562, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 564, "location-fragments" : [ { "start" : 15, "end" : 562, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-226, "familyName" : "CYTOCHROME P450 4G1-RELATED", "score" : 754.6, "model-ac" : "PTHR24291:SF106" }, { "signature" : { "accession" : "PS00086", "name" : "CYTOCHROME_P450", "description" : "Cytochrome P450 cysteine heme-iron ligand signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017972", "name" : "Cyt_P450_CS", "description" : "Cytochrome P450, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 502, "end" : 511, "level" : "STRONG", "cigarAlignment" : "2M1I7M", "alignment" : "FGaGPRGCLG", "location-fragments" : [ { "start" : 502, "end" : 511, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00086" }, { "signature" : { "accession" : "G3DSA:1.10.630.10", "name" : "Cytochrome p450", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036396", "name" : "Cyt_P450_sf", "description" : "Cytochrome P450 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 30, "end" : 315, "hmmStart" : 8, "hmmEnd" : 242, "hmmLength" : 487, "hmmBounds" : "COMPLETE", "evalue" : 6.2E-32, "score" : 112.7, "envelopeStart" : 30, "envelopeEnd" : 315, "postProcessed" : true, "location-fragments" : [ { "start" : 30, "end" : 315, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-110, "score" : 370.5, "model-ac" : "4d6zA00" }, { "signature" : { "accession" : "G3DSA:1.10.630.10", "name" : "Cytochrome p450", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036396", "name" : "Cyt_P450_sf", "description" : "Cytochrome P450 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 320, "end" : 567, "hmmStart" : 225, "hmmEnd" : 456, "hmmLength" : 487, "hmmBounds" : "COMPLETE", "evalue" : 4.8E-78, "score" : 265.2, "envelopeStart" : 320, "envelopeEnd" : 567, "postProcessed" : true, "location-fragments" : [ { "start" : 320, "end" : 567, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-97, "score" : 327.6, "model-ac" : "4zdzA01" }, { "signature" : { "accession" : "PR00385", "name" : "P450", "description" : "P450 superfamily signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001128", "name" : "Cyt_P450", "description" : "Cytochrome P450", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 423, "end" : 434, "pvalue" : 2.22E-4, "score" : 42.44, "motifNumber" : 3, "location-fragments" : [ { "start" : 423, "end" : 434, "dc-status" : "CONTINUOUS" } ] }, { "start" : 369, "end" : 386, "pvalue" : 1.8E-4, "score" : 30.41, "motifNumber" : 1, "location-fragments" : [ { "start" : 369, "end" : 386, "dc-status" : "CONTINUOUS" } ] }, { "start" : 500, "end" : 509, "pvalue" : 2.79E-5, "score" : 59.66, "motifNumber" : 4, "location-fragments" : [ { "start" : 500, "end" : 509, "dc-status" : "CONTINUOUS" } ] }, { "start" : 509, "end" : 520, "pvalue" : 3.96E-4, "score" : 39.54, "motifNumber" : 5, "location-fragments" : [ { "start" : 509, "end" : 520, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.2E-10, "graphscan" : "I.III", "model-ac" : "PR00385" }, { "signature" : { "accession" : "PR00463", "name" : "EP450I", "description" : "E-class P450 group I signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002401", "name" : "Cyt_P450_E_grp-I", "description" : "Cytochrome P450, E-class, group I", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 80, "end" : 99, "pvalue" : 0.0811, "score" : 25.02, "motifNumber" : 1, "location-fragments" : [ { "start" : 80, "end" : 99, "dc-status" : "CONTINUOUS" } ] }, { "start" : 378, "end" : 404, "pvalue" : 2.38E-6, "score" : 26.84, "motifNumber" : 5, "location-fragments" : [ { "start" : 378, "end" : 404, "dc-status" : "CONTINUOUS" } ] }, { "start" : 358, "end" : 375, "pvalue" : 3.43E-4, "score" : 26.72, "motifNumber" : 4, "location-fragments" : [ { "start" : 358, "end" : 375, "dc-status" : "CONTINUOUS" } ] }, { "start" : 509, "end" : 532, "pvalue" : 1.75E-6, "score" : 26.07, "motifNumber" : 9, "location-fragments" : [ { "start" : 509, "end" : 532, "dc-status" : "CONTINUOUS" } ] }, { "start" : 499, "end" : 509, "pvalue" : 2.9E-5, "score" : 55.67, "motifNumber" : 8, "location-fragments" : [ { "start" : 499, "end" : 509, "dc-status" : "CONTINUOUS" } ] }, { "start" : 422, "end" : 440, "pvalue" : 0.0107, "score" : 29.4, "motifNumber" : 6, "location-fragments" : [ { "start" : 422, "end" : 440, "dc-status" : "CONTINUOUS" } ] }, { "start" : 464, "end" : 488, "pvalue" : 4.19E-9, "score" : 33.52, "motifNumber" : 7, "location-fragments" : [ { "start" : 464, "end" : 488, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.9E-26, "graphscan" : "i..iiiIIi", "model-ac" : "PR00463" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 283, "end" : 303, "location-fragments" : [ { "start" : 283, "end" : 303, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR24291", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 562, "hmmStart" : 23, "hmmEnd" : 560, "hmmLength" : 562, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 564, "location-fragments" : [ { "start" : 15, "end" : 562, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-226, "familyName" : "CYTOCHROME P450 4G1-RELATED", "score" : 754.6, "model-ac" : "PTHR24291" } ], "xref" : [ { "name" : "XP_018909839.1 PREDICTED: cytochrome P450 4g15-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909839.1" }, { "name" : "XP_018909840.1 PREDICTED: cytochrome P450 4g15-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909840.1" } ] },{ "sequence" : "MRRLVILGFLGLCLGSELDNSIPTSGAGRYIGSGDELVNAVVNDCLAGDQSVVRCLKIRVLDYLDVSLNGGKRSLEAEDEVSDEELDSAIVHRVKKYITSHDFKLHMPDLFFQRATLVFKPASRALTDFDVEFPPPSENESRAISQAREDMQHKMVMPFLMMMKMMSKMITPVIMMMVGMKAMKALVLSKVAILLVGVFLFMQLCKKHGMMMPPGMGAMSVEPAPSSAYGPPSSAYGPPPTAPMNSYGAPPSNSYGSPASSSPAGSSSSYDQAPSSWEPAPSASNNQYSRVYDPHQVAYNAYSTIGASSSSSTKY", "md5" : "9b3359e336dd892d156cc7800b95345a", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 247, "end" : 289, "location-fragments" : [ { "start" : 247, "end" : 289, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR21879", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR012464", "name" : "DUF1676", "description" : "Protein of unknown function DUF1676", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 30, "end" : 238, "hmmStart" : 35, "hmmEnd" : 227, "hmmLength" : 282, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 250, "location-fragments" : [ { "start" : 30, "end" : 238, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-42, "familyName" : "OSIRIS 20", "score" : 147.8, "model-ac" : "PTHR21879" }, { "signature" : { "accession" : "PTHR21879:SF2", "name" : "OSIRIS 20", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 30, "end" : 238, "hmmStart" : 35, "hmmEnd" : 227, "hmmLength" : 282, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 250, "location-fragments" : [ { "start" : 30, "end" : 238, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-42, "familyName" : "OSIRIS 20", "score" : 147.8, "model-ac" : "PTHR21879:SF2" }, { "signature" : { "accession" : "PF07898", "name" : "DUF1676", "description" : "Protein of unknown function (DUF1676)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR012464", "name" : "DUF1676", "description" : "Protein of unknown function DUF1676", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 76, "end" : 200, "hmmStart" : 56, "hmmEnd" : 169, "hmmLength" : 172, "hmmBounds" : "INCOMPLETE", "evalue" : 2.0E-20, "score" : 73.6, "envelopeStart" : 68, "envelopeEnd" : 203, "postProcessed" : true, "location-fragments" : [ { "start" : 76, "end" : 200, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-21, "score" : 75.2, "model-ac" : "PF07898" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 240, "end" : 289, "location-fragments" : [ { "start" : 240, "end" : 289, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909768.1 PREDICTED: uncharacterized protein LOC109038947 [Bemisia tabaci]", "id" : "XP_018909768.1" } ] },{ "sequence" : "MPSDSMDDIELQNVQLQFPSARSLSREGSDVEEIKVETDRGHLLVAVQGNRSKPAIVTYHDLGLNYVSSFQAFFNYLDMRQLLNNFSVYHVNAPGQEEGAPPFPDDYEYPTMDDLAAQLNFVLTHFGLRSIIGLGVGAGGNILARFALSNPDKVEALCLINVVSTAAGWIEWGYQKLNARYLRSKGMTQGVLDYLMWHHFGRGTEERNHDLVQVYRNYFERCVNPGNLALFIDSYIRRTDLNIERDPDPNRRKEGGGSPTLSMPVMNITGSLSPHVNDTVTLNSRLDPSNSSWMKISDCGMVLEEQPNKVCEALRLFLQGLGYAVKLGRPKITNSTSAEAFIVMSVKTSRSLDSVRSAPWSIRITENPISETAAC", "md5" : "7bc0568fa38e8f5b20e0296a992a8caa", "matches" : [ { "signature" : { "accession" : "PF03096", "name" : "Ndr", "description" : "Ndr family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004142", "name" : "NDRG", "description" : "NDRG", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 35, "end" : 323, "hmmStart" : 3, "hmmEnd" : 281, "hmmLength" : 283, "hmmBounds" : "INCOMPLETE", "evalue" : 1.2E-103, "score" : 345.7, "envelopeStart" : 33, "envelopeEnd" : 325, "postProcessed" : true, "location-fragments" : [ { "start" : 35, "end" : 323, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.7E-104, "score" : 346.0, "model-ac" : "PF03096" }, { "signature" : { "accession" : "PTHR11034:SF19", "name" : "GH09802P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 34, "end" : 332, "hmmStart" : 3, "hmmEnd" : 294, "hmmLength" : 301, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 31, "envelopeEnd" : 344, "location-fragments" : [ { "start" : 34, "end" : 332, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-128, "familyName" : "GH09802P", "score" : 429.8, "model-ac" : "PTHR11034:SF19" }, { "signature" : { "accession" : "SSF53474", "name" : "alpha/beta-Hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 31, "end" : 319, "hmmLength" : 281, "location-fragments" : [ { "start" : 31, "end" : 319, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.24E-26, "model-ac" : "0046077" }, { "signature" : { "accession" : "PTHR11034", "name" : "N-MYC DOWNSTREAM REGULATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR004142", "name" : "NDRG", "description" : "NDRG", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 34, "end" : 332, "hmmStart" : 3, "hmmEnd" : 294, "hmmLength" : 301, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 31, "envelopeEnd" : 344, "location-fragments" : [ { "start" : 34, "end" : 332, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-128, "familyName" : "GH09802P", "score" : 429.8, "model-ac" : "PTHR11034" }, { "signature" : { "accession" : "G3DSA:3.40.50.1820", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 24, "end" : 320, "hmmStart" : 9, "hmmEnd" : 286, "hmmLength" : 286, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-93, "score" : 314.7, "envelopeStart" : 24, "envelopeEnd" : 320, "postProcessed" : true, "location-fragments" : [ { "start" : 24, "end" : 320, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-93, "score" : 315.0, "model-ac" : "2qmqA00" } ], "xref" : [ { "name" : "XP_018910101.1 PREDICTED: protein NDRG3 isoform X6 [Bemisia tabaci]", "id" : "XP_018910101.1" } ] },{ "sequence" : "MCTPEPLWPLLPESLSIDRPLPLTLLLNFKSIIIIIVVLFSDAIQVTIEFSVHKIHSVIFELGYLSEPSRCALHLLKVSFPVVLAPFYPTYKVTTTTTTKNKVQDSSSVFQPTTHSSQQCKTFQKMGSNEELKNFLEQALRNALQTALVNFQQTPPPPQ", "md5" : "83cd16238d14c0675314a9f4ed29ac2c", "matches" : [ ], "xref" : [ { "name" : "XP_018910558.1 PREDICTED: uncharacterized protein LOC109039513 [Bemisia tabaci]", "id" : "XP_018910558.1" } ] },{ "sequence" : "MRDDVMVVMSLLTSPCDSHVAGSKGLLNGPGQNNCFLNSAVQVLWHLDIFRRSFRELSGHTCMAESCIFCALKELFSQLQSSHENALPPDALRRALAESFFDQQRFQLGFMDDAAECFENMLLRIHYHLACNESEDMCRALHCIPHRKFAMTLVEQSVCGSCGATSEPLPFTQMVHYVSASALTAQAKQTAMPSHPDLFGQLLKKAGGMGDIRDCPSACGAKIQIQRTLMNKPEIVSVGVVWDSDRPSLEHIMAVLGTLRTSLRLSDVFNGCDAPGSPQHELVGVVTYYGKHYSTFFFHTKLRVWIYFDDATVREVGPRWEQVVEKCRRGRYQPLLLLFAVPEGTPLDTTNAPKTITRAQNKPMNGFMRSSLCKPLQPGMVPNLNSPTIIGGRRSLTPSPEKPNGMNGMNQRRAVTPNPDQTQDKPKIMNDYQNLSLIQVSINKPPDSPTRCSLNSYGMQSPAHKRNEIVRRDSGNWSGDRNSASSSSSTSLENPYLYIVNKMQLRGSNGVPRSPTSIKPGELSSSSTGSGGVCDPGYDSYSLSSTDSLPLQQSLKHNLQLAQIPEGHQTPINGVGAYANGLPNSIDDCERLCAEADQLLGRSEEAPDLETALSLANAAAGKARAAMDAPYSNPQTASFARMKHNSCIMRARSLHRKLEEPLNTKHGEGRHSREGSGISTRGSSHSRQNSADKSNIHHSRQNSRELLASTPALSPSQLSTKLDRHIESKLPSTNERSGPNKNIEIYATLPKSKKGLLSRSSSNGSTNKSGHIMEDEEYVYDRPGRSLYSSRSKSGKKEMEKRARSEERNSKKQQEFVSNSLPKEKDSKAKKAEKKAEAKAKQEETKEAGKKQHKIRRKLLMGGLIKRKNRSMPDLRDDEIAAKEPSAISTGSLKIMAKDDSVVGKHSKLDKDSSSGLSDYLSEGHLEYSANPNLERSKLMRKSFHSSKLIHFAKVPPPPPLRTTSQLSKTDQPQYPLPNNQNHLKEHKNWNNEPLSLPFMTHYGEKPKTDSITYANGGILLHNYPQTNTLVTKALVHQEQHTSPVKTPDIDVVDGMIVNKVEDVATAFPLPPYPSPLVSATHSRQASEEFPPPPPSVVPLAEDNGGFDEPESSLLLELRQKRQQILTESVERDVTEAVAITKSLGGGDTWLKELQAKQAALRGKTLLKNSPVITNLNDATSRLPTQTDVSTIKAASPVQQPAVDEQCSLVKDLKSKFEQIKIPRTDSEPIRSVSSPCESPATLGQNPGPSPNFEQIEKAPYPTKSIIDLDPKRRSGKKKNVTFCEQVVLVATADDDEVDSFIPNPILERVLRSVLHKDSPAIDVSRDVKSVVPLKRTDSCNKYEQSLSLRNSSSTNIDDQPSTQSNDETPSQPLTKAVSDQIANANAQSQNPSPVASQIVSHSSVYQHATKVQHSPLFNRPMTANAYQQVPVSNSQRVSQPLPSPSYQSNQPAASAHAYQANETPSPQYTHSQVSQQHRASTQPTTHQHSSQYSHQLNSHSHPIQYSSHQQAQSQVSNQQSPQTQTNHHQHHPQSPSTSQYSPSHPSHPHSSSQSPYQHVPAPAQQNSSPHLPPTGPPLTSPYQPIPSSPHHSQSHPPTSPYQQVPSQHSPSPHLSQSPSHLSQSPYQQVPNLQSNNPYQKHGPNNAQHSSSYHGSHHSSPQTNMPNQQLSNSNHYDQHVNSHSPYQQVPYANGSSSETHSHPSSMSHSTSYQSLPSQSSSNHSNQSSISSSVYQHVPHPQQSSPSYHSTNGNQQFHSNERPNSSPYQHIPQSSPASQQYQKSTLGMSPSAYQSVPSHSPSQSSDQGQSNHLPNHNPHASMNGHQHSNPGRPYDPRTNNFSQSSGNLAHPDIRGQSDRFSTHHGQAAIHSSYQQNSLKMQSRHQPIARTTIAPPSQQMLSRNQRVQGIYQQDPPEYQHPPSPRISIPNGNHIPNGNHIPNGHVPNSNHLPNGNHLPNGAHIPNGHIPNGGHMGKDGDTQSEVYQRIPLNAQAQMKQRQLIDHHNSVNQQLSYGPGKYPVPQHVPNTTKVIENGTVKGSPQGLAHLRTIQCNLCRKKDIIPPAVYCADCDFYMSRFKPKA", "md5" : "343da52274874f12d5efa692b73b4afd", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 652, "end" : 675, "location-fragments" : [ { "start" : 652, "end" : 675, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1224, "end" : 1252, "location-fragments" : [ { "start" : 1224, "end" : 1252, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 397, "end" : 424, "location-fragments" : [ { "start" : 397, "end" : 424, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 445, "end" : 462, "location-fragments" : [ { "start" : 445, "end" : 462, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1586, "end" : 1850, "location-fragments" : [ { "start" : 1586, "end" : 1850, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1416, "end" : 1882, "location-fragments" : [ { "start" : 1416, "end" : 1882, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1343, "end" : 1402, "location-fragments" : [ { "start" : 1343, "end" : 1402, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 507, "end" : 531, "location-fragments" : [ { "start" : 507, "end" : 531, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1567, "end" : 1585, "location-fragments" : [ { "start" : 1567, "end" : 1585, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 754, "end" : 769, "location-fragments" : [ { "start" : 754, "end" : 769, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1228, "end" : 1252, "location-fragments" : [ { "start" : 1228, "end" : 1252, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1416, "end" : 1566, "location-fragments" : [ { "start" : 1416, "end" : 1566, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 701, "end" : 721, "location-fragments" : [ { "start" : 701, "end" : 721, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 651, "end" : 871, "location-fragments" : [ { "start" : 651, "end" : 871, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF54001", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038765", "name" : "Papain-like_cys_pep_sf", "description" : "Papain-like cysteine peptidase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 24, "end" : 340, "hmmLength" : 347, "location-fragments" : [ { "start" : 24, "end" : 340, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.08E-30, "model-ac" : "0041295" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1859, "end" : 1882, "location-fragments" : [ { "start" : 1859, "end" : 1882, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50235", "name" : "USP_3", "description" : "Ubiquitin specific protease (USP) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR028889", "name" : "USP_dom", "description" : "Ubiquitin specific protease domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 24, "end" : 342, "score" : 22.994, "alignment" : "KGLLNGpgQNNCFLNSAVQVLWHLDIFRRSFReLSGHTCMAESCIFCALKELFSQLQSSHENALPPDALRRALAESFFDQqrfQLGFMDDAAECFENMLLRIHYHL----------------ACNESEDMCRALHCIPHRKFAMTLVEQSVCGSCGATseplpFTQMVHYVSASALTAQAKQTAMPSHPDLFGQLLKKAGGMGDIRD-----CpSACGAKIQ--IQRTLMNKPEIVSVGVVWDSDRPSLEHIMAVLGTLRTSLRLSDVFNG----CDAPGSPQHELVGVVTYYGK----HYSTFFFHTKLRVWIYFDDATVREVGPRweqvvekcRRGRYQPLLLLFAVP", "location-fragments" : [ { "start" : 24, "end" : 342, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50235" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 791, "end" : 850, "location-fragments" : [ { "start" : 791, "end" : 850, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 445, "end" : 489, "location-fragments" : [ { "start" : 445, "end" : 489, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR22975", "name" : "UBIQUITIN SPECIFIC PROTEINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 849, "hmmStart" : 37, "hmmEnd" : 912, "hmmLength" : 1267, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 948, "location-fragments" : [ { "start" : 14, "end" : 849, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-158, "familyName" : "ECHINUS SPLICE FORM 3", "score" : 532.2, "model-ac" : "PTHR22975" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 824, "end" : 848, "location-fragments" : [ { "start" : 824, "end" : 848, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 400, "end" : 424, "location-fragments" : [ { "start" : 400, "end" : 424, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1905, "end" : 1982, "location-fragments" : [ { "start" : 1905, "end" : 1982, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 676, "end" : 690, "location-fragments" : [ { "start" : 676, "end" : 690, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR22975:SF9", "name" : "ECHINUS SPLICE FORM 3", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 849, "hmmStart" : 37, "hmmEnd" : 912, "hmmLength" : 1267, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 948, "location-fragments" : [ { "start" : 14, "end" : 849, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-158, "familyName" : "ECHINUS SPLICE FORM 3", "score" : 532.2, "model-ac" : "PTHR22975:SF9" }, { "signature" : { "accession" : "G3DSA:3.90.70.10", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 340, "hmmStart" : 7, "hmmEnd" : 311, "hmmLength" : 317, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-30, "score" : 107.1, "envelopeStart" : 25, "envelopeEnd" : 340, "postProcessed" : true, "location-fragments" : [ { "start" : 25, "end" : 340, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-30, "score" : 107.1, "model-ac" : "1vjvA01" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1923, "end" : 1953, "location-fragments" : [ { "start" : 1923, "end" : 1953, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910180.1 PREDICTED: histone-lysine N-methyltransferase, H3 lysine-79 specific-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910180.1" }, { "name" : "XP_018910181.1 PREDICTED: histone-lysine N-methyltransferase, H3 lysine-79 specific-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910181.1" }, { "name" : "XP_018910179.1 PREDICTED: histone-lysine N-methyltransferase, H3 lysine-79 specific-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910179.1" } ] },{ "sequence" : "MSVSTTAIITPYALVAMLLWHRQRKECRFCKPSWSRAPALCAIILCVGTFVIFSITTRGYSDPNKAVLGWEPSKNLSVAAFLETVDVNGRREDSENGSVCDSELLLLVVVCSSPEKEALRTAIRQTWASLQDQSVRVVFLLGHPLPSHESAYVQSRISREKEMYQDIIQEDFIDSYNNLTIKSIMMLRWFTKNCERTSYLLKTDDDIFLDFRVLNQSLRRPFPKWIAPDNFLGGTLIRGASPNKDNNDKWFMPNYLYAGSKYPNYLSGTAYLMSRQVAEKLFTASFGVNMIHMEDIYITGLCARKAGVRPFSLFGFTLSKVKRMGCKSRHIMSHRVTPADMYRIWNTRAACSEFYVTSIFQDRQFGLWEKVANKLHGGR", "md5" : "4cb3f4baf45554d0befe9e40c12ae00b", "matches" : [ { "signature" : { "accession" : "PF01762", "name" : "Galactosyl_T", "description" : "Galactosyltransferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002659", "name" : "Glyco_trans_31", "description" : "Glycosyl transferase, family 31", "type" : "FAMILY", "goXRefs" : [ { "name" : "protein glycosylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006486" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 120, "end" : 310, "hmmStart" : 3, "hmmEnd" : 191, "hmmLength" : 195, "hmmBounds" : "INCOMPLETE", "evalue" : 2.7E-45, "score" : 154.6, "envelopeStart" : 118, "envelopeEnd" : 313, "postProcessed" : true, "location-fragments" : [ { "start" : 120, "end" : 310, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-45, "score" : 155.0, "model-ac" : "PF01762" }, { "signature" : { "accession" : "PTHR11214:SF148", "name" : "HEXOSYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 94, "end" : 338, "hmmStart" : 74, "hmmEnd" : 297, "hmmLength" : 303, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 42, "envelopeEnd" : 356, "location-fragments" : [ { "start" : 94, "end" : 338, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.3E-67, "familyName" : "HEXOSYLTRANSFERASE", "score" : 227.9, "model-ac" : "PTHR11214:SF148" }, { "signature" : { "accession" : "PTHR11214", "name" : "BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR002659", "name" : "Glyco_trans_31", "description" : "Glycosyl transferase, family 31", "type" : "FAMILY", "goXRefs" : [ { "name" : "protein glycosylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006486" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 94, "end" : 338, "hmmStart" : 74, "hmmEnd" : 297, "hmmLength" : 303, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 42, "envelopeEnd" : 356, "location-fragments" : [ { "start" : 94, "end" : 338, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.3E-67, "familyName" : "HEXOSYLTRANSFERASE", "score" : 227.9, "model-ac" : "PTHR11214" } ], "xref" : [ { "name" : "XP_018910328.1 PREDICTED: beta-1,3-galactosyltransferase 1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910328.1" }, { "name" : "XP_018910331.1 PREDICTED: beta-1,3-galactosyltransferase 1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910331.1" }, { "name" : "XP_018910327.1 PREDICTED: beta-1,3-galactosyltransferase 1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910327.1" }, { "name" : "XP_018910325.1 PREDICTED: beta-1,3-galactosyltransferase 1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910325.1" }, { "name" : "XP_018910329.1 PREDICTED: beta-1,3-galactosyltransferase 1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910329.1" }, { "name" : "XP_018910330.1 PREDICTED: beta-1,3-galactosyltransferase 1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910330.1" } ] },{ "sequence" : "MIPMHVCRTRLPKQCQKQMEYHRKTVKHLLEVPQPGIAATGVSIYFYYLAYCEDAIERVCLLPKEIFHEVVRMVGSRVYVGGLPYGCREKDLEKFFKGYGRIRDILLKNGYGFVEFEDNRDAEDAVYELNGRPLMGERITVERARGTDRSRRGFGGGGRFGGGGGRYGGGRRRTPDTFRYGPPRRTDYRVIVENLSSRISWQDLKDFMRKAGEVSYADAHRINRNEGVVEFTSYSEMKTAIEKLDGTELNGRRIRLIEDKRKSRRSYSSSSRSRSRSRSRSRSNRNRSRSHSKSARKSRSRSRLPAKKRDSKSPSRSRSPVADKSSRSPSKKRSRSRSPAPKKHSRSSSSHSKSHSRSPVKKRSKARSPSADSDRRYSESPRKDRSASPGMKNGDRSGDED", "md5" : "a55385d010b0ee37268b8fbf5391a821", "matches" : [ { "signature" : { "accession" : "cd12337", "name" : "RRM1_SRSF4_like", "description" : "RRM1_SRSF4_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR035585", "name" : "RRM1_SRSF4-like", "description" : "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "RNA Polymerase II Transcription Termination", "databaseName" : "Reactome", "id" : "R-HSA-73856" }, { "name" : "mRNA 3'-end processing", "databaseName" : "Reactome", "id" : "R-HSA-72187" }, { "name" : "mRNA Splicing - Major Pathway", "databaseName" : "Reactome", "id" : "R-HSA-72163" }, { "name" : "Transport of Mature mRNA derived from an Intron-Containing Transcript", "databaseName" : "Reactome", "id" : "R-HSA-159236" } ] } }, "locations" : [ { "start" : 77, "end" : 146, "sites" : [ ], "evalue" : 2.32806E-37, "score" : 127.828, "location-fragments" : [ { "start" : 77, "end" : 146, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12337" }, { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 188, "end" : 261, "score" : 12.526, "alignment" : "YRVIVENLSSRISWQDLKDFMRKAGEVSYADAHR----INRNEGVVEFTSYSEMKTAIEKLDGTELNGRRIRLIEDKR", "location-fragments" : [ { "start" : 188, "end" : 261, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" }, { "signature" : { "accession" : "PTHR23147", "name" : "SERINE/ARGININE RICH SPLICING FACTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 76, "end" : 340, "hmmStart" : 2, "hmmEnd" : 261, "hmmLength" : 448, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 75, "envelopeEnd" : 344, "location-fragments" : [ { "start" : 76, "end" : 340, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.4E-89, "familyName" : "SERINE/ARGININE-RICH SPLICING FACTOR 4", "score" : 302.2, "model-ac" : "PTHR23147" }, { "signature" : { "accession" : "PTHR23147:SF55", "name" : "SERINE/ARGININE-RICH SPLICING FACTOR 4", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 76, "end" : 340, "hmmStart" : 2, "hmmEnd" : 261, "hmmLength" : 448, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 75, "envelopeEnd" : 344, "location-fragments" : [ { "start" : 76, "end" : 340, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.4E-89, "familyName" : "SERINE/ARGININE-RICH SPLICING FACTOR 4", "score" : 302.2, "model-ac" : "PTHR23147:SF55" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 255, "end" : 401, "location-fragments" : [ { "start" : 255, "end" : 401, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00360", "name" : "rrm1_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 189, "end" : 257, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 6.9E-12, "score" : 55.5, "location-fragments" : [ { "start" : 189, "end" : 257, "dc-status" : "CONTINUOUS" } ] }, { "start" : 77, "end" : 142, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-21, "score" : 87.0, "location-fragments" : [ { "start" : 77, "end" : 142, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-38, "score" : 142.5, "model-ac" : "SM00360" }, { "signature" : { "accession" : "PF00076", "name" : "RRM_1", "description" : "RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 78, "end" : 139, "hmmStart" : 1, "hmmEnd" : 69, "hmmLength" : 70, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.1E-19, "score" : 67.9, "envelopeStart" : 78, "envelopeEnd" : 140, "postProcessed" : true, "location-fragments" : [ { "start" : 78, "end" : 139, "dc-status" : "CONTINUOUS" } ] }, { "start" : 190, "end" : 255, "hmmStart" : 1, "hmmEnd" : 70, "hmmLength" : 70, "hmmBounds" : "COMPLETE", "evalue" : 4.1E-13, "score" : 49.0, "envelopeStart" : 190, "envelopeEnd" : 255, "postProcessed" : true, "location-fragments" : [ { "start" : 190, "end" : 255, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.2E-35, "score" : 118.9, "model-ac" : "PF00076" }, { "signature" : { "accession" : "cd12600", "name" : "RRM2_SRSF4_like", "description" : "RRM2_SRSF4_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 188, "end" : 259, "sites" : [ ], "evalue" : 4.57163E-46, "score" : 150.981, "location-fragments" : [ { "start" : 188, "end" : 259, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12600" }, { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 76, "end" : 146, "score" : 18.325, "alignment" : "SRVYVGGLPYGCREKDLEKFFKGYGRIRDILL-------KNGYGFVEFEDNRDAEDAVYELNGRPLMGERITVERARG", "location-fragments" : [ { "start" : 76, "end" : 146, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 187, "end" : 260, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 77, "hmmBounds" : "COMPLETE", "evalue" : 3.3E-24, "score" : 86.6, "envelopeStart" : 187, "envelopeEnd" : 260, "postProcessed" : true, "location-fragments" : [ { "start" : 187, "end" : 260, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-45, "score" : 153.5, "model-ac" : "1wg4A01" }, { "signature" : { "accession" : "SSF54928", "name" : "RNA-binding domain, RBD", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035979", "name" : "RBD_domain_sf", "description" : "RNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 77, "end" : 260, "hmmLength" : 183, "location-fragments" : [ { "start" : 185, "end" : 260, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 77, "end" : 156, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.43E-37, "model-ac" : "0049769" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 365, "end" : 401, "location-fragments" : [ { "start" : 365, "end" : 401, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 73, "end" : 176, "hmmStart" : 14, "hmmEnd" : 108, "hmmLength" : 126, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-23, "score" : 84.6, "envelopeStart" : 73, "envelopeEnd" : 176, "postProcessed" : true, "location-fragments" : [ { "start" : 73, "end" : 176, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-38, "score" : 132.1, "model-ac" : "4pkdB02" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 267, "end" : 306, "location-fragments" : [ { "start" : 267, "end" : 306, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 330, "end" : 364, "location-fragments" : [ { "start" : 330, "end" : 364, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910446.1 PREDICTED: serine/arginine-rich splicing factor 5-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910446.1" }, { "name" : "XP_018910447.1 PREDICTED: serine/arginine-rich splicing factor 5-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910447.1" } ] },{ "sequence" : "MYKIAFISVIFSLVFNYYHALNVDHKQLDWWQRAVFYQIYPRSFKDSDGDGIGDLKGIAEKIWYLKDLGITGVWFNPVLESPGLDLGYDISNFTNLDPLFGTMEDFQYLREALYKAGIHLFLDIVPNHTSDQHDWFLKSVKKIDPYTNYYIWKDPKIVNGQRQPPTNWLSEFGGSTWKWHEERNQYYLHQFHWKQPDLNYDCEELVQEMMDVVRFWLERGVDGMRFDAVAYLFEDPEWRDQELLSPDLDPTNYWNYNRSRTMDQPNTYRLITRFREVFDFYTKKEGKTKVLMTEAYTTLDRTMDYYQFEGKPGAHMPFNFFFITHVSGRSPAKDYQKAIQGWMDSMPAGFWPNWVMGNHDNRRVAARYGSDLVDGVNMIGLCLPGIGNTYYGDEIGMDDTVIRFDQGVDPQACHGGPEWYSQKSRDPARTPFQWDTSLNSGFTTNRKTWLPVNSNFWRLNLKAQMQAGENSHWKVYKRLMSVRKTDTILYGDLETFVLTKYVFAFVRRLEGSEAYVVVVNLGSDSQSIDLLAFMSDLPDVLTVHTSSVNSQYLPNDKVSTNGFFLRPKASVLLTTAKEVPPPAYTDPANGSSTIHTVYFSFIITLFIYVFFS", "md5" : "e67e5fb4dab5bee3008e3e1ab5c18b29", "matches" : [ { "signature" : { "accession" : "PF00128", "name" : "Alpha-amylase", "description" : "Alpha amylase, catalytic domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006047", "name" : "Glyco_hydro_13_cat_dom", "description" : "Glycosyl hydrolase, family 13, catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 53, "end" : 400, "hmmStart" : 1, "hmmEnd" : 333, "hmmLength" : 336, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.3E-90, "score" : 303.6, "envelopeStart" : 53, "envelopeEnd" : 403, "postProcessed" : true, "location-fragments" : [ { "start" : 53, "end" : 400, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-90, "score" : 304.1, "model-ac" : "PF00128" }, { "signature" : { "accession" : "SM00642", "name" : "aamy", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006047", "name" : "Glyco_hydro_13_cat_dom", "description" : "Glycosyl hydrolase, family 13, catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 38, "end" : 429, "hmmStart" : 1, "hmmEnd" : 547, "hmmLength" : 547, "hmmBounds" : "COMPLETE", "evalue" : 7.7E-109, "score" : 377.6, "location-fragments" : [ { "start" : 38, "end" : 429, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.7E-109, "score" : 377.6, "model-ac" : "SM00642" }, { "signature" : { "accession" : "G3DSA:3.90.400.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 130, "end" : 202, "hmmStart" : 1, "hmmEnd" : 451, "hmmLength" : 452, "hmmBounds" : "INCOMPLETE", "evalue" : 2.5E-153, "score" : 513.3, "envelopeStart" : 30, "envelopeEnd" : 485, "postProcessed" : true, "location-fragments" : [ { "start" : 130, "end" : 202, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-153, "score" : 513.6, "model-ac" : "3wy1A02" }, { "signature" : { "accession" : "PTHR10357:SF177", "name" : "FI17312P1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 20, "end" : 583, "hmmStart" : 23, "hmmEnd" : 589, "hmmLength" : 605, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 598, "location-fragments" : [ { "start" : 20, "end" : 583, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-206, "familyName" : "FI17312P1-RELATED", "score" : 689.1, "model-ac" : "PTHR10357:SF177" }, { "signature" : { "accession" : "G3DSA:3.20.20.80", "name" : "Glycosidases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 30, "end" : 484, "hmmStart" : 1, "hmmEnd" : 451, "hmmLength" : 394, "hmmBounds" : "INCOMPLETE", "evalue" : 2.5E-153, "score" : 513.3, "envelopeStart" : 30, "envelopeEnd" : 485, "postProcessed" : true, "location-fragments" : [ { "start" : 203, "end" : 484, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 30, "end" : 129, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.2E-153, "score" : 513.6, "model-ac" : "3wy1A01" }, { "signature" : { "accession" : "SSF51445", "name" : "(Trans)glycosidases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR017853", "name" : "Glycoside_hydrolase_SF", "description" : "Glycoside hydrolase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 29, "end" : 485, "hmmLength" : 479, "location-fragments" : [ { "start" : 29, "end" : 485, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.18E-112, "model-ac" : "0044469" }, { "signature" : { "accession" : "PTHR10357", "name" : "ALPHA-AMYLASE FAMILY MEMBER", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 20, "end" : 583, "hmmStart" : 23, "hmmEnd" : 589, "hmmLength" : 605, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 598, "location-fragments" : [ { "start" : 20, "end" : 583, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-206, "familyName" : "FI17312P1-RELATED", "score" : 689.1, "model-ac" : "PTHR10357" }, { "signature" : { "accession" : "cd11328", "name" : "AmyAc_maltase", "description" : "AmyAc_maltase", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 28, "end" : 494, "sites" : [ { "description" : "catalytic site", "numLocations" : 3, "siteLocations" : [ { "start" : 227, "end" : 227, "residue" : "D" }, { "start" : 294, "end" : 294, "residue" : "E" }, { "start" : 360, "end" : 360, "residue" : "D" } ] }, { "description" : "active site", "numLocations" : 11, "siteLocations" : [ { "start" : 195, "end" : 195, "residue" : "Q" }, { "start" : 227, "end" : 227, "residue" : "D" }, { "start" : 294, "end" : 294, "residue" : "E" }, { "start" : 191, "end" : 191, "residue" : "F" }, { "start" : 172, "end" : 172, "residue" : "F" }, { "start" : 359, "end" : 359, "residue" : "H" }, { "start" : 88, "end" : 88, "residue" : "Y" }, { "start" : 128, "end" : 128, "residue" : "H" }, { "start" : 125, "end" : 125, "residue" : "V" }, { "start" : 360, "end" : 360, "residue" : "D" }, { "start" : 85, "end" : 85, "residue" : "D" } ] } ], "evalue" : 0.0, "score" : 719.013, "location-fragments" : [ { "start" : 28, "end" : 494, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd11328" } ], "xref" : [ { "name" : "XP_018910472.1 PREDICTED: maltase 2-like [Bemisia tabaci]", "id" : "XP_018910472.1" } ] },{ "sequence" : "MDALPLIPQLLHSFKIIRDHSPHYNSPANPKNPLINAENAELSSRAGCSTVPTGSSPARFPIEDSAGDPILTIADEDNLAGSTAHPPRSTISAVASIDAVETADGAMNVEAFGADSGPKPCVIPAVTVGHEVVRFRDHAPLRGGSRGACPAVAAILAGPPRAPDGENVEQPPVDNPLCDAEKASGGGAVRPIGAIFSCLRFTLRLRQIPGDGLDDFRVGHSFPSRFVILNFGDHKRDAVLELVEIFDHGDGVFGELHEVIPVLPDPNCRIAHGEKHEKMSQLCRALSNQVIISCRNLIDLSILFEGRTRSSMKIFQECIRCCSTYKSMYNKVKLTNDATGDSQWNSDLKIILNSVDTFMERCQEMIELCETMLIYGRLDETQDVPKPTFGFTRGAEFEKVCDKIEDLFHESFSKVEQVQDCILDVQSSDWYREMNRFRKDMKKIDTIAENLILESFNMVKNVEEGLLTLQSLYEYSKRPSLFNVIEKKTAMVYKMFWDELQEAKLSLLSEKNSYARLMPKYAGRAWTSLVKKTQLKSLYDLFQEKLWLPKVTIAVEIESLYQDVIQTFDEAILSNYKRWLEVAESKIGVRLKRSLICRSLQKPGLLEVNIDRKLLYVFSEAKLWVDMGFPIPNEMSQLVARRNELTLLYRNVETCVQNYNRVMASLSDSERVLFRDLIRGQDRELSVCWRMSWASEAASARVLVSTEQLQELQSFIDDYKTHNVRIVRLCERICATALVHVEMKLYELHHLVAQVQACRFTAMAQLIRNYNKIFKRLRSLFEGFKNPTRATMFHFMQYVEKIDTVLLEAFRLCVKNSMQKILSYLRGDLIKGPKPFVVLYLTLSKENEVEFIPSLTACCSFLRNIFYDLLISIKVIPRLATKFNPAAKVEPYAARIARDKESTRLQVQVEREIQKLVSEVDIHVQKWAPLEDIWSVDKDIFMKNYEKSNPCADTYETDINRHNSLMETIDSAPDRGQVYFLLIDSVLLKRGLTEHCADWKSRLLELLFQTTSAAITRTHDYATRNIARITTKPRSATEILDSIKTHKQLMSELEVMKLRFVTIESNVRVYLKVAKSIPGALLEQKGAMEEAWRDYERILGEINAVLNDSAQQTSKLLFERGRAREKDTRPYLENVLSDPTFTDQWNVEDASKYLNEVLSQLQRIYRDLEKA", "md5" : "2e1f5cd535006a030494595af8d5fe95", "matches" : [ { "signature" : { "accession" : "PF08385", "name" : "DHC_N1", "description" : "Dynein heavy chain, N-terminal region 1", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013594", "name" : "Dynein_heavy_dom-1", "description" : "Dynein heavy chain, domain-1", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 276, "end" : 696, "hmmStart" : 137, "hmmEnd" : 557, "hmmLength" : 562, "hmmBounds" : "INCOMPLETE", "evalue" : 3.2E-70, "score" : 237.5, "envelopeStart" : 270, "envelopeEnd" : 700, "postProcessed" : true, "location-fragments" : [ { "start" : 276, "end" : 696, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-70, "score" : 237.5, "model-ac" : "PF08385" }, { "signature" : { "accession" : "PTHR22878", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 276, "end" : 1154, "hmmStart" : 342, "hmmEnd" : 1237, "hmmLength" : 4515, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 271, "envelopeEnd" : 1167, "location-fragments" : [ { "start" : 276, "end" : 1154, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-80, "familyName" : "", "score" : 271.1, "model-ac" : "PTHR22878" }, { "signature" : { "accession" : "PTHR22878:SF61", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 276, "end" : 1154, "hmmStart" : 342, "hmmEnd" : 1237, "hmmLength" : 4515, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 271, "envelopeEnd" : 1167, "location-fragments" : [ { "start" : 276, "end" : 1154, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-80, "familyName" : "", "score" : 271.1, "model-ac" : "PTHR22878:SF61" } ], "xref" : [ { "name" : "XP_018910320.1 PREDICTED: dynein heavy chain 2, axonemal [Bemisia tabaci]", "id" : "XP_018910320.1" } ] },{ "sequence" : "MQLLAHTPWSVCPIMSTIPLPNSTAEKRRPQMYDINCGIRTRVFTSPPSAYKFDYSIHDPNTNDIKSQWEHRDGDLVKGAYKLLEPDGSTRLVEYTADKDNGFHATVTREDGDREPQEPPSGSAFPSGLDDY", "md5" : "cdeea96fd8c4a7f419edd94adf97530d", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 102, "end" : 117, "location-fragments" : [ { "start" : 102, "end" : 117, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 102, "end" : 132, "location-fragments" : [ { "start" : 102, "end" : 132, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51155", "name" : "CHIT_BIND_RR_2", "description" : "Chitin-binding type R&R domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000618", "name" : "Insect_cuticle", "description" : "Insect cuticle protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of cuticle", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0042302" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 48, "end" : 119, "score" : 17.322, "alignment" : "PSAYKFDYSIHDPNTNDIKSQwEHRDGD--LVKGAYKLLEPDGSTRLVEYTADkDNGFHATVTredgDREPQEP", "location-fragments" : [ { "start" : 48, "end" : 119, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51155" }, { "signature" : { "accession" : "PF00379", "name" : "Chitin_bind_4", "description" : "Insect cuticle protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000618", "name" : "Insect_cuticle", "description" : "Insect cuticle protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of cuticle", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0042302" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 51, "end" : 103, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 9.8E-13, "score" : 48.4, "envelopeStart" : 51, "envelopeEnd" : 103, "postProcessed" : true, "location-fragments" : [ { "start" : 51, "end" : 103, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-13, "score" : 49.2, "model-ac" : "PF00379" }, { "signature" : { "accession" : "PS00233", "name" : "CHIT_BIND_RR_1", "description" : "Chitin-binding type R&R domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR031311", "name" : "CHIT_BIND_RR_consensus", "description" : "Chitin-binding type R&R consensus", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 79, "end" : 105, "level" : "STRONG", "cigarAlignment" : "1M7I2M6I1M1I2M3I2M1I1M", "alignment" : "GaykllepDGstrlveYtADkdnGFhA", "location-fragments" : [ { "start" : 79, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00233" }, { "signature" : { "accession" : "PR00947", "name" : "CUTICLE", "description" : "Insect cuticle protein signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000618", "name" : "Insect_cuticle", "description" : "Insect cuticle protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of cuticle", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0042302" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 88, "end" : 99, "pvalue" : 1.95E-5, "score" : 47.95, "motifNumber" : 3, "location-fragments" : [ { "start" : 88, "end" : 99, "dc-status" : "CONTINUOUS" } ] }, { "start" : 49, "end" : 60, "pvalue" : 9.85E-4, "score" : 26.78, "motifNumber" : 1, "location-fragments" : [ { "start" : 49, "end" : 60, "dc-status" : "CONTINUOUS" } ] }, { "start" : 77, "end" : 88, "pvalue" : 4.81E-6, "score" : 45.08, "motifNumber" : 2, "location-fragments" : [ { "start" : 77, "end" : 88, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-7, "graphscan" : "iII", "model-ac" : "PR00947" }, { "signature" : { "accession" : "PTHR12236:SF75", "name" : "CCP84AC-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 47, "end" : 118, "hmmStart" : 91, "hmmEnd" : 164, "hmmLength" : 183, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 9, "envelopeEnd" : 130, "location-fragments" : [ { "start" : 47, "end" : 118, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-30, "familyName" : "CCP84AC-RELATED", "score" : 109.3, "model-ac" : "PTHR12236:SF75" }, { "signature" : { "accession" : "PTHR12236", "name" : "STRUCTURAL CONTITUENT OF CUTICLE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 47, "end" : 118, "hmmStart" : 91, "hmmEnd" : 164, "hmmLength" : 183, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 9, "envelopeEnd" : 130, "location-fragments" : [ { "start" : 47, "end" : 118, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-30, "familyName" : "CCP84AC-RELATED", "score" : 109.3, "model-ac" : "PTHR12236" } ], "xref" : [ { "name" : "XP_018910464.1 PREDICTED: cuticle protein 19-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910464.1" } ] },{ "sequence" : "MLKLNFLREWTQWLRPLVALVYSVIILVLVPYLTIAAFEESTTKKDSFVYLIAGIFVMMAVPISFWEIVQHMIHYTKPSLQKHIIRILWMVPIYAFNAWFGLVFPTRVLYLNSLRECYEAYVIYSFMKFLFNYLDDADPFLETTLAKKSQTKHIFPFCWMTNWRMGRELIHRCKHGILQYTIVRPMTSLAAIVCDWFGVYHEGELSTGSYPYIIAVNNVSQIFAMYCLVLFYRATKEELAPMKPIGKFLSIKCVIFFSFFQGVIITILVNAGVISQVFDVETRDSVREIASKLQNFLICIEMFLASIAHYFTFTHVPFINLTYQNPSVSAAFSAMWDVSDIGADLKEHFGIMGDSIRVVIGRGYIIESSESSSLISGPSKILPYYVIDPSMEVSDQDEGSKTSLSKSSDPTIHSDKTTNSDKVSKSDNESKK", "md5" : "31a512e41b0e118fbc542895483ea880", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 393, "end" : 432, "location-fragments" : [ { "start" : 393, "end" : 432, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 396, "end" : 414, "location-fragments" : [ { "start" : 396, "end" : 414, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR23423", "name" : "ORGANIC SOLUTE TRANSPORTER-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR005178", "name" : "Ostalpha/TMEM184C", "description" : "Organic solute transporter subunit alpha/Transmembrane protein 184", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 34, "end" : 421, "hmmStart" : 10, "hmmEnd" : 373, "hmmLength" : 457, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 26, "envelopeEnd" : 432, "location-fragments" : [ { "start" : 34, "end" : 421, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-122, "familyName" : "TRANSMEMBRANE PROTEIN 184C", "score" : 412.9, "model-ac" : "PTHR23423" }, { "signature" : { "accession" : "PF03619", "name" : "Solute_trans_a", "description" : "Organic solute transporter Ostalpha", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005178", "name" : "Ostalpha/TMEM184C", "description" : "Organic solute transporter subunit alpha/Transmembrane protein 184", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 318, "hmmStart" : 2, "hmmEnd" : 265, "hmmLength" : 265, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.2E-91, "score" : 304.4, "envelopeStart" : 49, "envelopeEnd" : 318, "postProcessed" : true, "location-fragments" : [ { "start" : 50, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-91, "score" : 305.0, "model-ac" : "PF03619" }, { "signature" : { "accession" : "PTHR23423:SF10", "name" : "TRANSMEMBRANE PROTEIN 184C", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 34, "end" : 421, "hmmStart" : 10, "hmmEnd" : 373, "hmmLength" : 457, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 26, "envelopeEnd" : 432, "location-fragments" : [ { "start" : 34, "end" : 421, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-122, "familyName" : "TRANSMEMBRANE PROTEIN 184C", "score" : 412.9, "model-ac" : "PTHR23423:SF10" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 415, "end" : 432, "location-fragments" : [ { "start" : 415, "end" : 432, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910344.1 PREDICTED: transmembrane protein 184C [Bemisia tabaci]", "id" : "XP_018910344.1" } ] },{ "sequence" : "MSSEQCSLGSILPPNYRHRAEAFARDLQQRLWSLGGGRSSSDDRLTKRAHNLALDAAHSAAGQPFEPCPPYAAFEEDSSPRSPTLEPGTDPLAQLVNRSDGLPIPQSAEEGSPRCSFSADSQQSIYSTPSDNFSLPASSIPYRDNPSPEPPVQHTPVDTCDLFRDLYNSLDHTNQERSAKDPSHQTELPTQAIHLQASLTNGVVDRESDSVNSLANSFNKISLNGGISDECHCENSAISRFEILENSDRNANDLVKNRNEPGKPRLDSGSSVDTISNDSLNVCESEMPLSPDSLNSLDSLSTLHSPDSLNSLNSFDALKETERTVSEENGCKCEVEEESKEERLSAPSECERTKLRRSSSLKTWKTPPDTPGHKKIVRFADVLGLDLADVRTFMDEIPQIPRSAYSDLSGIDADLFTSTTSPSVESTSVPTPKYLVPLFQQPGGMLDFFDKLSLRNVCLENAVVTDPALLAVAGTIRVRNVDFDKSVFVRYSLDGWRSFADLKAMYVVNSCDGYSDQFSFVLYAHTLEIGDRLEFAVLFQTKGDQYWDNNGGINYIFQCVPPPPAVAATMANIGTPNMGEKYGGFY", "md5" : "3f049ce46c19820d81befa8a6818790e", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 57, "end" : 155, "location-fragments" : [ { "start" : 57, "end" : 155, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:2.60.40.2440", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR038175", "name" : "CBM21_dom_sf", "description" : "CBM21 domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 429, "end" : 561, "hmmStart" : 8, "hmmEnd" : 135, "hmmLength" : 139, "hmmBounds" : "COMPLETE", "evalue" : 5.8E-36, "score" : 125.3, "envelopeStart" : 429, "envelopeEnd" : 561, "postProcessed" : true, "location-fragments" : [ { "start" : 429, "end" : 561, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-36, "score" : 126.1, "model-ac" : "2m83A00" }, { "signature" : { "accession" : "PTHR12307", "name" : "PROTEIN PHOSPHATASE 1 BINDING PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 173, "end" : 565, "hmmStart" : 69, "hmmEnd" : 422, "hmmLength" : 436, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 150, "envelopeEnd" : 580, "location-fragments" : [ { "start" : 173, "end" : 565, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-102, "familyName" : "GLYCOGEN-BINDING SUBUNIT 76A", "score" : 346.2, "model-ac" : "PTHR12307" }, { "signature" : { "accession" : "PTHR12307:SF44", "name" : "GLYCOGEN-BINDING SUBUNIT 76A", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 173, "end" : 565, "hmmStart" : 69, "hmmEnd" : 422, "hmmLength" : 436, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 150, "envelopeEnd" : 580, "location-fragments" : [ { "start" : 173, "end" : 565, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-102, "familyName" : "GLYCOGEN-BINDING SUBUNIT 76A", "score" : 346.2, "model-ac" : "PTHR12307:SF44" }, { "signature" : { "accession" : "PS51159", "name" : "CBM21", "description" : "CBM21 (carbohydrate binding type-21) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR005036", "name" : "CBM21_dom", "description" : "CBM21 (carbohydrate binding type-21) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 449, "end" : 558, "score" : 23.742, "alignment" : "FDKLSLRNVCLenaVVTDPALLAVAGTIRVRNVDFDKSVFVRYSLDGWRSFADLKAMYVVNS-CDGYSDQFSFVLYAHTLEIGDRLEFAVLFQTKGDQYWDNNGGINYIFQ", "location-fragments" : [ { "start" : 449, "end" : 558, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51159" }, { "signature" : { "accession" : "PF03370", "name" : "CBM_21", "description" : "Carbohydrate/starch-binding module (family 21)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005036", "name" : "CBM21_dom", "description" : "CBM21 (carbohydrate binding type-21) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 455, "end" : 557, "hmmStart" : 5, "hmmEnd" : 112, "hmmLength" : 113, "hmmBounds" : "INCOMPLETE", "evalue" : 8.8E-25, "score" : 87.1, "envelopeStart" : 451, "envelopeEnd" : 558, "postProcessed" : true, "location-fragments" : [ { "start" : 455, "end" : 557, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-25, "score" : 87.7, "model-ac" : "PF03370" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 111, "end" : 141, "location-fragments" : [ { "start" : 111, "end" : 141, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 257, "end" : 279, "location-fragments" : [ { "start" : 257, "end" : 279, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909637.1 PREDICTED: glycogen-binding subunit 76A [Bemisia tabaci]", "id" : "XP_018909637.1" } ] },{ "sequence" : "MNFPMAFYDKSPKYSKNQLGSLHYGTAGFRTRAENLGHVAYRVGIIAALRSRVRNGQAIGVMITASHNPEDDNGIKIVDPMGEMLEGAWETYATDMVNTPDASLEQFLQRVIATHQVNLKAKSLVFLGWDTRPSSLSLSIATSDGVESMGGKLNSIGLTSTPIIHFLVMCWNTNEEYGRANEAGYYSKLSSAFNHVHNVDEPKKLYTPEISVDCANGVGALVLKKMIHFLQELQSSSSPNKKSLKINLFNDLVFVKDVLNNECGADFVKVQQKIPIMKKKDGSSLHVIPNARYASVDGDADRIIYYYVDDSGIFHLLDGDRIAILVAGYLKELIKKTGINIQVGLVQTAYANGSSTKYAIEKLNIPVAWTLTGVKHLHHKAKEFDIGVYFEANGHGTVLFNSRTVEHLTKLLVDERNGLSEDQKANLKKLLVVRDVINETVGDAIADLLLVEAILYDSDWNIQQWLNLYDDLPNRQLKVSLQDCSVVKTEGADVKCIAPAGLQQKINSLVKNYPSGRAFIRPSGTENFVRIYAEADSQKNADSLAAEVAQAVHSLAGNVGDLYEHPL", "md5" : "63f110c46bf75b4229ce8e48ff310359", "matches" : [ { "signature" : { "accession" : "SSF53738", "name" : "Phosphoglucomutase, first 3 domains", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016055", "name" : "A-D-PHexomutase_a/b/a-I/II/III", "description" : "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "intramolecular transferase activity, phosphotransferases", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016868" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+5.4.2.10" }, { "name" : "CMP-legionaminate biosynthesis I", "databaseName" : "MetaCyc", "id" : "PWY-6749" } ] } }, "locations" : [ { "start" : 298, "end" : 397, "hmmLength" : 120, "location-fragments" : [ { "start" : 298, "end" : 397, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-5, "model-ac" : "0040059" }, { "signature" : { "accession" : "PIRSF016408", "name" : "PAGM", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR016657", "name" : "PAGM", "description" : "Phosphoacetylglucosamine mutase", "type" : "FAMILY", "goXRefs" : [ { "name" : "phosphoacetylglucosamine mutase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004610" } ], "pathwayXRefs" : [ { "name" : "UDP-N-acetyl-D-galactosamine biosynthesis II", "databaseName" : "MetaCyc", "id" : "PWY-5514" }, { "name" : "Chitin derivatives degradation", "databaseName" : "MetaCyc", "id" : "PWY-6906" }, { "name" : "Synthesis of UDP-N-acetyl-glucosamine", "databaseName" : "Reactome", "id" : "R-HSA-446210" }, { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+5.4.2.3" } ] } }, "locations" : [ { "start" : 2, "end" : 559, "hmmStart" : 8, "hmmEnd" : 556, "hmmLength" : 561, "hmmBounds" : "INCOMPLETE", "evalue" : 2.7E-186, "score" : 615.8, "envelopeStart" : 2, "envelopeEnd" : 559, "postProcessed" : false, "location-fragments" : [ { "start" : 2, "end" : 559, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-186, "score" : 616.1, "model-ac" : "PIRSF016408" }, { "signature" : { "accession" : "cd03086", "name" : "PGM3", "description" : "PGM3", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR016657", "name" : "PAGM", "description" : "Phosphoacetylglucosamine mutase", "type" : "FAMILY", "goXRefs" : [ { "name" : "phosphoacetylglucosamine mutase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004610" } ], "pathwayXRefs" : [ { "name" : "UDP-N-acetyl-D-galactosamine biosynthesis II", "databaseName" : "MetaCyc", "id" : "PWY-5514" }, { "name" : "Chitin derivatives degradation", "databaseName" : "MetaCyc", "id" : "PWY-6906" }, { "name" : "Synthesis of UDP-N-acetyl-glucosamine", "databaseName" : "Reactome", "id" : "R-HSA-446210" }, { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+5.4.2.3" } ] } }, "locations" : [ { "start" : 24, "end" : 552, "sites" : [ { "description" : "substrate binding site", "numLocations" : 11, "siteLocations" : [ { "start" : 523, "end" : 523, "residue" : "S" }, { "start" : 374, "end" : 374, "residue" : "V" }, { "start" : 524, "end" : 524, "residue" : "G" }, { "start" : 391, "end" : 391, "residue" : "E" }, { "start" : 372, "end" : 372, "residue" : "T" }, { "start" : 521, "end" : 521, "residue" : "R" }, { "start" : 373, "end" : 373, "residue" : "G" }, { "start" : 393, "end" : 393, "residue" : "N" }, { "start" : 525, "end" : 525, "residue" : "T" }, { "start" : 530, "end" : 530, "residue" : "R" }, { "start" : 395, "end" : 395, "residue" : "H" } ] }, { "description" : "metal binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 299, "end" : 299, "residue" : "D" }, { "start" : 297, "end" : 297, "residue" : "D" }, { "start" : 301, "end" : 301, "residue" : "D" } ] }, { "description" : "active site", "numLocations" : 18, "siteLocations" : [ { "start" : 374, "end" : 374, "residue" : "V" }, { "start" : 524, "end" : 524, "residue" : "G" }, { "start" : 391, "end" : 391, "residue" : "E" }, { "start" : 297, "end" : 297, "residue" : "D" }, { "start" : 66, "end" : 66, "residue" : "S" }, { "start" : 373, "end" : 373, "residue" : "G" }, { "start" : 393, "end" : 393, "residue" : "N" }, { "start" : 67, "end" : 67, "residue" : "H" }, { "start" : 301, "end" : 301, "residue" : "D" }, { "start" : 523, "end" : 523, "residue" : "S" }, { "start" : 299, "end" : 299, "residue" : "D" }, { "start" : 30, "end" : 30, "residue" : "R" }, { "start" : 302, "end" : 302, "residue" : "R" }, { "start" : 372, "end" : 372, "residue" : "T" }, { "start" : 521, "end" : 521, "residue" : "R" }, { "start" : 525, "end" : 525, "residue" : "T" }, { "start" : 530, "end" : 530, "residue" : "R" }, { "start" : 395, "end" : 395, "residue" : "H" } ] } ], "evalue" : 0.0, "score" : 725.925, "location-fragments" : [ { "start" : 24, "end" : 552, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd03086" }, { "signature" : { "accession" : "PF00408", "name" : "PGM_PMM_IV", "description" : "Phosphoglucomutase/phosphomannomutase, C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005843", "name" : "A-D-PHexomutase_C", "description" : "Alpha-D-phosphohexomutase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intramolecular transferase activity, phosphotransferases", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016868" }, { "name" : "organic substance metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0071704" } ], "pathwayXRefs" : [ { "name" : "CMP-legionaminate biosynthesis I", "databaseName" : "MetaCyc", "id" : "PWY-6749" }, { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+5.4.2.10" } ] } }, "locations" : [ { "start" : 503, "end" : 552, "hmmStart" : 23, "hmmEnd" : 73, "hmmLength" : 74, "hmmBounds" : "INCOMPLETE", "evalue" : 2.2E-10, "score" : 40.5, "envelopeStart" : 477, "envelopeEnd" : 553, "postProcessed" : true, "location-fragments" : [ { "start" : 503, "end" : 552, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.6E-11, "score" : 42.0, "model-ac" : "PF00408" }, { "signature" : { "accession" : "PF02880", "name" : "PGM_PMM_III", "description" : "Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005846", "name" : "A-D-PHexomutase_a/b/a-III", "description" : "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intramolecular transferase activity, phosphotransferases", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016868" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+5.4.2.10" }, { "name" : "CMP-legionaminate biosynthesis I", "databaseName" : "MetaCyc", "id" : "PWY-6749" } ] } }, "locations" : [ { "start" : 318, "end" : 399, "hmmStart" : 1, "hmmEnd" : 77, "hmmLength" : 114, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.9E-5, "score" : 23.5, "envelopeStart" : 318, "envelopeEnd" : 419, "postProcessed" : true, "location-fragments" : [ { "start" : 318, "end" : 399, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-5, "score" : 24.9, "model-ac" : "PF02880" }, { "signature" : { "accession" : "SSF55957", "name" : "Phosphoglucomutase, C-terminal domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036900", "name" : "A-D-PHexomutase_C_sf", "description" : "Alpha-D-phosphohexomutase, C-terminal domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "intramolecular transferase activity, phosphotransferases", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016868" }, { "name" : "organic substance metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0071704" } ], "pathwayXRefs" : [ { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+5.4.2.10" }, { "name" : "CMP-legionaminate biosynthesis I", "databaseName" : "MetaCyc", "id" : "PWY-6749" } ] } }, "locations" : [ { "start" : 460, "end" : 559, "hmmLength" : 112, "location-fragments" : [ { "start" : 460, "end" : 559, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.22E-23, "model-ac" : "0050632" }, { "signature" : { "accession" : "G3DSA:3.40.120.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 317, "end" : 396, "hmmStart" : 4, "hmmEnd" : 158, "hmmLength" : 84, "hmmBounds" : "INCOMPLETE", "evalue" : 9.8E-8, "score" : 33.7, "envelopeStart" : 208, "envelopeEnd" : 405, "postProcessed" : true, "location-fragments" : [ { "start" : 317, "end" : 396, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-9, "score" : 38.6, "model-ac" : "3pdkA03" }, { "signature" : { "accession" : "G3DSA:3.40.120.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 210, "end" : 314, "hmmStart" : 4, "hmmEnd" : 158, "hmmLength" : 130, "hmmBounds" : "INCOMPLETE", "evalue" : 9.8E-8, "score" : 33.7, "envelopeStart" : 208, "envelopeEnd" : 405, "postProcessed" : true, "location-fragments" : [ { "start" : 210, "end" : 314, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-9, "score" : 38.6, "model-ac" : "3pdkA02" }, { "signature" : { "accession" : "SSF53738", "name" : "Phosphoglucomutase, first 3 domains", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016055", "name" : "A-D-PHexomutase_a/b/a-I/II/III", "description" : "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "intramolecular transferase activity, phosphotransferases", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016868" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+5.4.2.10" }, { "name" : "CMP-legionaminate biosynthesis I", "databaseName" : "MetaCyc", "id" : "PWY-6749" } ] } }, "locations" : [ { "start" : 20, "end" : 100, "hmmLength" : 190, "location-fragments" : [ { "start" : 20, "end" : 100, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.73E-13, "model-ac" : "0045549" }, { "signature" : { "accession" : "PF02878", "name" : "PGM_PMM_I", "description" : "Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005844", "name" : "A-D-PHexomutase_a/b/a-I", "description" : "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intramolecular transferase activity, phosphotransferases", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016868" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "CMP-legionaminate biosynthesis I", "databaseName" : "MetaCyc", "id" : "PWY-6749" }, { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+5.4.2.10" } ] } }, "locations" : [ { "start" : 54, "end" : 91, "hmmStart" : 87, "hmmEnd" : 125, "hmmLength" : 138, "hmmBounds" : "INCOMPLETE", "evalue" : 2.7E-8, "score" : 33.6, "envelopeStart" : 35, "envelopeEnd" : 103, "postProcessed" : true, "location-fragments" : [ { "start" : 54, "end" : 91, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-15, "score" : 56.3, "model-ac" : "PF02878" }, { "signature" : { "accession" : "PTHR45955", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 560, "hmmStart" : 30, "hmmEnd" : 562, "hmmLength" : 565, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 563, "location-fragments" : [ { "start" : 15, "end" : 560, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-202, "familyName" : "FAMILY NOT NAMED", "score" : 674.8, "model-ac" : "PTHR45955" }, { "signature" : { "accession" : "SSF53738", "name" : "Phosphoglucomutase, first 3 domains", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016055", "name" : "A-D-PHexomutase_a/b/a-I/II/III", "description" : "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "intramolecular transferase activity, phosphotransferases", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016868" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+5.4.2.10" }, { "name" : "CMP-legionaminate biosynthesis I", "databaseName" : "MetaCyc", "id" : "PWY-6749" } ] } }, "locations" : [ { "start" : 184, "end" : 311, "hmmLength" : 104, "location-fragments" : [ { "start" : 184, "end" : 311, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.56E-6, "model-ac" : "0039874" }, { "signature" : { "accession" : "G3DSA:3.30.310.50", "name" : "Major birch pollen allergen Bet v 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 473, "end" : 557, "hmmStart" : 1, "hmmEnd" : 85, "hmmLength" : 85, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-29, "score" : 103.4, "envelopeStart" : 473, "envelopeEnd" : 557, "postProcessed" : true, "location-fragments" : [ { "start" : 473, "end" : 557, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-29, "score" : 104.4, "model-ac" : "1wjwA01" }, { "signature" : { "accession" : "PS00710", "name" : "PGM_PMM", "description" : "Phosphoglucomutase and phosphomannomutase phosphoserine signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR016066", "name" : "A-D-PHexomutase_CS", "description" : "Alpha-D-phosphohexomutase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "magnesium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0000287" } ], "pathwayXRefs" : [ { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+5.4.2.10" }, { "name" : "CMP-legionaminate biosynthesis I", "databaseName" : "MetaCyc", "id" : "PWY-6749" } ] } }, "locations" : [ { "start" : 60, "end" : 69, "level" : "STRONG", "cigarAlignment" : "2M1I7M", "alignment" : "GVmITASHNP", "location-fragments" : [ { "start" : 60, "end" : 69, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00710" }, { "signature" : { "accession" : "SSF53738", "name" : "Phosphoglucomutase, first 3 domains", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016055", "name" : "A-D-PHexomutase_a/b/a-I/II/III", "description" : "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "intramolecular transferase activity, phosphotransferases", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016868" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+5.4.2.10" }, { "name" : "CMP-legionaminate biosynthesis I", "databaseName" : "MetaCyc", "id" : "PWY-6749" } ] } }, "locations" : [ { "start" : 79, "end" : 195, "hmmLength" : 150, "location-fragments" : [ { "start" : 79, "end" : 195, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.63E-12, "model-ac" : "0039873" }, { "signature" : { "accession" : "G3DSA:1.10.490.170", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 177, "hmmStart" : 11, "hmmEnd" : 177, "hmmLength" : 181, "hmmBounds" : "COMPLETE", "evalue" : 3.5E-58, "score" : 198.0, "envelopeStart" : 3, "envelopeEnd" : 177, "postProcessed" : true, "location-fragments" : [ { "start" : 3, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-58, "score" : 199.5, "model-ac" : "4bjuA01" } ], "xref" : [ { "name" : "XP_018910428.1 PREDICTED: phosphoacetylglucosamine mutase-like [Bemisia tabaci]", "id" : "XP_018910428.1" } ] },{ "sequence" : "MGAEDAASAESFLKPFLAALASFMCQFQLGAILGQSSTMLPQLQAEDSPIRITKEYASWIASAGVIGTPIASVLAGPLTDKMGRKSVIRMHFLLSAIGHTIVGVSSDGTEILIGRVILSCATGFGVPSLVYIPEICNPRHRSPLLFTATVSSSLGLVYVYTLGGILSWDITSMLTSSLAIIGLVYTFIVPESPAWLFRSHRLNEAIDSIKWLKGQNVNMELELRSLKDACHEQPKERVSLLKQFASPTVIKPFLVLTIISFLQNASGFYILLYYSIDFFLEFKSSYDPRFVSVGLAVTRLVSCTVASVIINRFCRKTMGTFSGLSMGVILLGILGYLHEFGDDAEVLSRYSWVPAAGLTLYVFACSLGVHPLPWLMIFELYPLEVRGRMCGISNGMCYVFTFVFTKLYYTFIANFKIQGTILLFMVASVLFGLFSAFVLPETQGKTLVEIEDRFRPKKKPDKESTLP", "md5" : "797ebc8e4ddb19d1258f36748c3807eb", "matches" : [ { "signature" : { "accession" : "PTHR23500", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 458, "hmmStart" : 46, "hmmEnd" : 504, "hmmLength" : 547, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 466, "location-fragments" : [ { "start" : 11, "end" : 458, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-84, "familyName" : "", "score" : 287.1, "model-ac" : "PTHR23500" }, { "signature" : { "accession" : "cd17358", "name" : "MFS_GLUT6_8_Class3_like", "description" : "MFS_GLUT6_8_Class3_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 449, "sites" : [ { "description" : "chemical substrate binding pocket", "numLocations" : 21, "siteLocations" : [ { "start" : 366, "end" : 366, "residue" : "S" }, { "start" : 299, "end" : 299, "residue" : "R" }, { "start" : 369, "end" : 369, "residue" : "V" }, { "start" : 153, "end" : 153, "residue" : "S" }, { "start" : 272, "end" : 272, "residue" : "L" }, { "start" : 401, "end" : 401, "residue" : "T" }, { "start" : 263, "end" : 263, "residue" : "Q" }, { "start" : 398, "end" : 398, "residue" : "Y" }, { "start" : 149, "end" : 149, "residue" : "T" }, { "start" : 152, "end" : 152, "residue" : "S" }, { "start" : 370, "end" : 370, "residue" : "H" }, { "start" : 264, "end" : 264, "residue" : "N" }, { "start" : 29, "end" : 29, "residue" : "L" }, { "start" : 268, "end" : 268, "residue" : "F" }, { "start" : 269, "end" : 269, "residue" : "Y" }, { "start" : 156, "end" : 156, "residue" : "L" }, { "start" : 33, "end" : 33, "residue" : "L" }, { "start" : 273, "end" : 273, "residue" : "Y" }, { "start" : 374, "end" : 374, "residue" : "W" }, { "start" : 365, "end" : 365, "residue" : "C" }, { "start" : 397, "end" : 397, "residue" : "C" } ] } ], "evalue" : 1.24542E-75, "score" : 241.711, "location-fragments" : [ { "start" : 16, "end" : 449, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd17358" }, { "signature" : { "accession" : "SSF103473", "name" : "MFS general substrate transporter", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036259", "name" : "MFS_trans_sf", "description" : "MFS transporter superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 19, "end" : 452, "hmmLength" : 417, "location-fragments" : [ { "start" : 231, "end" : 452, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 19, "end" : 204, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.88E-49, "model-ac" : "0042480" }, { "signature" : { "accession" : "PF00083", "name" : "Sugar_tr", "description" : "Sugar (and other) transporter", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005828", "name" : "MFS_sugar_transport-like", "description" : "Major facilitator, sugar transporter-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 16, "end" : 453, "hmmStart" : 3, "hmmEnd" : 451, "hmmLength" : 452, "hmmBounds" : "INCOMPLETE", "evalue" : 9.2E-54, "score" : 183.0, "envelopeStart" : 14, "envelopeEnd" : 454, "postProcessed" : true, "location-fragments" : [ { "start" : 16, "end" : 453, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.0E-54, "score" : 183.2, "model-ac" : "PF00083" }, { "signature" : { "accession" : "G3DSA:1.20.1250.20", "name" : "MFS general substrate transporter like domains", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 457, "hmmStart" : 15, "hmmEnd" : 466, "hmmLength" : 470, "hmmBounds" : "COMPLETE", "evalue" : 2.0E-83, "score" : 282.8, "envelopeStart" : 10, "envelopeEnd" : 457, "postProcessed" : true, "location-fragments" : [ { "start" : 10, "end" : 457, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-83, "score" : 283.2, "model-ac" : "4zw9A00" }, { "signature" : { "accession" : "PS50850", "name" : "MFS", "description" : "Major facilitator superfamily (MFS) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR020846", "name" : "MFS_dom", "description" : "Major facilitator superfamily domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 443, "score" : 23.543, "alignment" : "KPFLAALASFMCQFQLGAIlgqsSTMLPQLQAEDSPIRitkEYASWIASAGVIGTPIASVLAGPLTDKMGRKSVIRMHFLLSAIGHTIVGVSSDGTEILIGRVILSCATGFGVPSLVYIP-EICNPRHRSPLLFT----ATVSSSLGLVYVYTLGGILSWDITSMLTSSLAIIGLVYT-FIVPESPAWlfrshrlneaidsikwlkgqnvnmelelRSLKDACHEQPKERVSLLKQFASPTVikPFLVLTIISFLQNASGFYILLYYSIDFFLEFKSSYDPRFVSVGLAVTR----LVSCTVASVIINRFCRkTMGTFSGLSMGVILLGILGYLHEFGDdaevlsrysWVPAAGLTLYVFACSLGVHPLPWLMIFELYPLEVRGRMCGISNGMCYVFTFVFTKLYYTFIANFKIQGTILLFMVASVLFGLFSAFVLPETQ", "location-fragments" : [ { "start" : 14, "end" : 443, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50850" }, { "signature" : { "accession" : "PTHR23500:SF457", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 458, "hmmStart" : 46, "hmmEnd" : 504, "hmmLength" : 547, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 466, "location-fragments" : [ { "start" : 11, "end" : 458, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-84, "familyName" : "", "score" : 287.1, "model-ac" : "PTHR23500:SF457" } ], "xref" : [ { "name" : "XP_018909895.1 PREDICTED: facilitated trehalose transporter Tret1-like [Bemisia tabaci]", "id" : "XP_018909895.1" } ] },{ "sequence" : "MEVDVEEEEIQLHLSSNDDSCSSNQPQQRNLTVEVEIHAPPTKSRHSEEVHGPSKASSDELSDILKKHKLSLIVDESTDKGDSKNLVLATRYFGSKVCDARDRFFDLITLPKGKADHVSLYNSVKTSFEQKDVPYKENLIGFGADGCNVMHGCHHSVKTLLMKDCPFPFTSTCICHSFALCVNKGVAELPRHSEDCLRDFCNFIKNSAIRYAHLKAYQVICELKPNKMLKKVDTRWLSLGDVMARVIRYD", "md5" : "14133babd2d6f0763e25c10f9b5df4bf", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 32, "location-fragments" : [ { "start" : 15, "end" : 32, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF53098", "name" : "Ribonuclease H-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR012337", "name" : "RNaseH-like_sf", "description" : "Ribonuclease H-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 62, "end" : 246, "hmmLength" : 447, "location-fragments" : [ { "start" : 62, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.29E-7, "model-ac" : "0052065" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 59, "location-fragments" : [ { "start" : 1, "end" : 59, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR37162", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 54, "end" : 248, "hmmStart" : 117, "hmmEnd" : 308, "hmmLength" : 608, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 39, "envelopeEnd" : 250, "location-fragments" : [ { "start" : 54, "end" : 248, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-42, "familyName" : "FAMILY NOT NAMED", "score" : 148.3, "model-ac" : "PTHR37162" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 39, "end" : 59, "location-fragments" : [ { "start" : 39, "end" : 59, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910437.1 PREDICTED: uncharacterized protein LOC109039422, partial [Bemisia tabaci]", "id" : "XP_018910437.1" } ] },{ "sequence" : "MMNGGVGVPLPPQPPMQAMMPPGGAVPYPPTQNGDGPPPMKQARLENGVAAPFLAAPIYDVNQTGALVPGPGSRSGLIGILSAPLPKLSHDQQDAVNKAKKYAMEQSIKMVLMKQTLAHQQQLLANQKNQFQRQQALALMCRVYVGSISFELKEDTIRQAFLPFGPIKSINMSWDPVTQKHKGFAFVEYDIPEAAQLSLEQMNGVMLGGRNIKVVGRPSNMPQAQCVIDEITEEAKQYNRIYVASIHPDLSEDDIKSVFEAFGPIKSCKLGQGSSPHRHKGYAFIEYETKNASQEAIASMNLFDLGGQYLRVGRAITPPNALHGPSTSTSHMPTAAAVAAAAATAKIQAMDAVASNTLIGLSKLGQLNPGATIPATTVPGLQTLAPVLQAVPGQLPVGAAIPPPGIAIPQQIRAPVPIIPVGQPLIAPPTVVNPVLSQGLPNMNNPDALRRAQEQAQQKQQEELQKKLLEETEPQTLQQQENMSIKGQSARHLVMQKLMRKVESRVVILRNMVGPEDVDETLQEEIQDECSKYGLVQRVIIYNEKQSEEVDDHNAEVIVKIFVEFSQMREAENARDALNGRFFGGRLVKAELYDQALFDHSDFSG", "md5" : "155b616f3099847182ce151b513c34f7", "matches" : [ { "signature" : { "accession" : "cd12648", "name" : "RRM3_UHM_PUF60", "description" : "RRM3_UHM_PUF60", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR034212", "name" : "PUF60_RRM3", "description" : "PUF60, RNA recognition motif 3", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "mRNA Splicing - Major Pathway", "databaseName" : "Reactome", "id" : "R-HSA-72163" } ] } }, "locations" : [ { "start" : 504, "end" : 604, "sites" : [ { "description" : "oligomer interface", "numLocations" : 17, "siteLocations" : [ { "start" : 540, "end" : 540, "residue" : "I" }, { "start" : 547, "end" : 547, "residue" : "S" }, { "start" : 553, "end" : 553, "residue" : "H" }, { "start" : 601, "end" : 601, "residue" : "S" }, { "start" : 537, "end" : 537, "residue" : "Q" }, { "start" : 541, "end" : 541, "residue" : "I" }, { "start" : 549, "end" : 549, "residue" : "E" }, { "start" : 599, "end" : 599, "residue" : "D" }, { "start" : 600, "end" : 600, "residue" : "H" }, { "start" : 542, "end" : 542, "residue" : "Y" }, { "start" : 545, "end" : 545, "residue" : "K" }, { "start" : 546, "end" : 546, "residue" : "Q" }, { "start" : 538, "end" : 538, "residue" : "R" }, { "start" : 566, "end" : 566, "residue" : "S" }, { "start" : 548, "end" : 548, "residue" : "E" }, { "start" : 602, "end" : 602, "residue" : "D" }, { "start" : 603, "end" : 603, "residue" : "F" } ] } ], "evalue" : 1.48151E-57, "score" : 186.457, "location-fragments" : [ { "start" : 504, "end" : 604, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12648" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 130, "end" : 234, "hmmStart" : 4, "hmmEnd" : 108, "hmmLength" : 109, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.3E-26, "score" : 94.9, "envelopeStart" : 130, "envelopeEnd" : 238, "postProcessed" : true, "location-fragments" : [ { "start" : 130, "end" : 234, "dc-status" : "CONTINUOUS" } ] }, { "start" : 235, "end" : 322, "hmmStart" : 7, "hmmEnd" : 89, "hmmLength" : 109, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.7E-20, "score" : 73.5, "envelopeStart" : 230, "envelopeEnd" : 322, "postProcessed" : true, "location-fragments" : [ { "start" : 235, "end" : 322, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-58, "score" : 196.0, "model-ac" : "2qfjA01" }, { "signature" : { "accession" : "SSF54928", "name" : "RNA-binding domain, RBD", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035979", "name" : "RBD_domain_sf", "description" : "RNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 122, "end" : 214, "hmmLength" : 146, "location-fragments" : [ { "start" : 122, "end" : 214, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.18E-23, "model-ac" : "0047108" }, { "signature" : { "accession" : "SSF54928", "name" : "RNA-binding domain, RBD", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035979", "name" : "RBD_domain_sf", "description" : "RNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 238, "end" : 593, "hmmLength" : 183, "location-fragments" : [ { "start" : 238, "end" : 327, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 506, "end" : 593, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 2.8E-27, "model-ac" : "0049769" }, { "signature" : { "accession" : "TIGR01645", "name" : "TIGR01645", "description" : "half-pint: poly-U binding splicing factor, half-pint family", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR006532", "name" : "PolyU-bd", "description" : "Poly-U binding splicing factor, half-pint", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "mRNA Splicing - Major Pathway", "databaseName" : "Reactome", "id" : "R-HSA-72163" } ] } }, "locations" : [ { "start" : 52, "end" : 437, "hmmStart" : 19, "hmmEnd" : 398, "hmmLength" : 607, "hmmBounds" : "INCOMPLETE", "evalue" : 4.5E-158, "score" : 525.7, "envelopeStart" : 39, "envelopeEnd" : 451, "postProcessed" : false, "location-fragments" : [ { "start" : 52, "end" : 437, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-224, "score" : 744.7, "model-ac" : "TIGR01645" }, { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 239, "end" : 317, "score" : 16.057, "alignment" : "NRIYVASIHPDLSEDDIKSVFEAFGPIKSCKLGQGsSPHRHKGYAFIEYETKNASQEAIASMNLFDLGGQYLRVGRAIT", "location-fragments" : [ { "start" : 239, "end" : 317, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 456, "end" : 470, "location-fragments" : [ { "start" : 456, "end" : 470, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 36, "location-fragments" : [ { "start" : 8, "end" : 36, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd12370", "name" : "RRM1_PUF60", "description" : "RRM1_PUF60", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR034209", "name" : "PUF60_RRM1", "description" : "PUF60, RNA recognition motif 1", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "mRNA Splicing - Major Pathway", "databaseName" : "Reactome", "id" : "R-HSA-72163" } ] } }, "locations" : [ { "start" : 141, "end" : 217, "sites" : [ { "description" : "dimer interface", "numLocations" : 4, "siteLocations" : [ { "start" : 203, "end" : 203, "residue" : "N" }, { "start" : 215, "end" : 215, "residue" : "V" }, { "start" : 217, "end" : 217, "residue" : "R" }, { "start" : 216, "end" : 216, "residue" : "G" } ] } ], "evalue" : 6.98448E-53, "score" : 173.385, "location-fragments" : [ { "start" : 141, "end" : 217, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12370" }, { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 141, "end" : 214, "score" : 16.602, "alignment" : "CRVYVGSISFELKEDTIRQAFLPFGPIKSINMSWDpVTQKHKGFAFVEYDIPEAAQLSLEQMNGVMLGGRNIKV-----", "location-fragments" : [ { "start" : 141, "end" : 214, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" }, { "signature" : { "accession" : "SM00361", "name" : "rrm2_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003954", "name" : "RRM_dom_euk", "description" : "RNA recognition motif domain, eukaryote", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 506, "end" : 591, "hmmStart" : 1, "hmmEnd" : 91, "hmmLength" : 91, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-12, "score" : 57.8, "location-fragments" : [ { "start" : 506, "end" : 591, "dc-status" : "CONTINUOUS" } ] }, { "start" : 142, "end" : 215, "hmmStart" : 1, "hmmEnd" : 91, "hmmLength" : 91, "hmmBounds" : "COMPLETE", "evalue" : 0.06, "score" : 22.5, "location-fragments" : [ { "start" : 142, "end" : 215, "dc-status" : "CONTINUOUS" } ] }, { "start" : 240, "end" : 313, "hmmStart" : 1, "hmmEnd" : 91, "hmmLength" : 91, "hmmBounds" : "COMPLETE", "evalue" : 5.8, "score" : 6.3, "location-fragments" : [ { "start" : 240, "end" : 313, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-21, "score" : 86.6, "model-ac" : "SM00361" }, { "signature" : { "accession" : "cd12371", "name" : "RRM2_PUF60", "description" : "RRM2_PUF60", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR034211", "name" : "PUF60_RRM2", "description" : "PUF60, RNA recognition motif 2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "mRNA Splicing - Major Pathway", "databaseName" : "Reactome", "id" : "R-HSA-72163" } ] } }, "locations" : [ { "start" : 239, "end" : 315, "sites" : [ { "description" : "dimer interface", "numLocations" : 3, "siteLocations" : [ { "start" : 299, "end" : 299, "residue" : "S" }, { "start" : 294, "end" : 294, "residue" : "Q" }, { "start" : 298, "end" : 298, "residue" : "A" } ] } ], "evalue" : 5.57218E-47, "score" : 157.429, "location-fragments" : [ { "start" : 239, "end" : 315, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12371" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 504, "end" : 594, "hmmStart" : 2, "hmmEnd" : 88, "hmmLength" : 88, "hmmBounds" : "COMPLETE", "evalue" : 9.0E-27, "score" : 94.9, "envelopeStart" : 504, "envelopeEnd" : 594, "postProcessed" : true, "location-fragments" : [ { "start" : 504, "end" : 594, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-46, "score" : 157.8, "model-ac" : "3ue2A01" }, { "signature" : { "accession" : "PTHR47330", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 51, "end" : 605, "hmmStart" : 22, "hmmEnd" : 545, "hmmLength" : 545, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 38, "envelopeEnd" : 605, "location-fragments" : [ { "start" : 51, "end" : 605, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-236, "familyName" : "FAMILY NOT NAMED", "score" : 788.9, "model-ac" : "PTHR47330" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 442, "end" : 471, "location-fragments" : [ { "start" : 442, "end" : 471, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00360", "name" : "rrm1_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 142, "end" : 215, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-22, "score" : 90.7, "location-fragments" : [ { "start" : 142, "end" : 215, "dc-status" : "CONTINUOUS" } ] }, { "start" : 506, "end" : 591, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 0.01, "score" : 24.3, "location-fragments" : [ { "start" : 506, "end" : 591, "dc-status" : "CONTINUOUS" } ] }, { "start" : 240, "end" : 313, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 6.5E-19, "score" : 78.8, "location-fragments" : [ { "start" : 240, "end" : 313, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-53, "score" : 193.8, "model-ac" : "SM00360" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 451, "end" : 472, "location-fragments" : [ { "start" : 451, "end" : 472, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 36, "location-fragments" : [ { "start" : 1, "end" : 36, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00076", "name" : "RRM_1", "description" : "RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 521, "end" : 588, "hmmStart" : 10, "hmmEnd" : 69, "hmmLength" : 70, "hmmBounds" : "INCOMPLETE", "evalue" : 1.9E-4, "score" : 21.2, "envelopeStart" : 518, "envelopeEnd" : 589, "postProcessed" : true, "location-fragments" : [ { "start" : 521, "end" : 588, "dc-status" : "CONTINUOUS" } ] }, { "start" : 143, "end" : 213, "hmmStart" : 1, "hmmEnd" : 70, "hmmLength" : 70, "hmmBounds" : "COMPLETE", "evalue" : 7.9E-17, "score" : 60.9, "envelopeStart" : 143, "envelopeEnd" : 213, "postProcessed" : true, "location-fragments" : [ { "start" : 143, "end" : 213, "dc-status" : "CONTINUOUS" } ] }, { "start" : 241, "end" : 310, "hmmStart" : 1, "hmmEnd" : 69, "hmmLength" : 70, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.2E-15, "score" : 55.7, "envelopeStart" : 241, "envelopeEnd" : 311, "postProcessed" : true, "location-fragments" : [ { "start" : 241, "end" : 310, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-42, "score" : 143.7, "model-ac" : "PF00076" }, { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 505, "end" : 595, "score" : 10.036, "alignment" : "RVVILRNMVGpedvdETLQEEIQDECSKYGLVQRVIIYNEkqseevddHNAEVIVKIFVEFSQMREAENARDALNGRFFGGRLVKAELYDQ", "location-fragments" : [ { "start" : 505, "end" : 595, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" } ], "xref" : [ { "name" : "XP_018909853.1 PREDICTED: poly(U)-binding-splicing factor half pint isoform X1 [Bemisia tabaci]", "id" : "XP_018909853.1" } ] },{ "sequence" : "MFSQVKAIILLPKQPKPLQEIFKLHKRKMSSAATATEPEVPDDVLFESTDVFGVATLNRPKALNALNLSMVTKLTRKLEEWEKTKQFVIVKGAGEKAFCAGGDVRYATALEPSQNSRGKTFFRNEYIMNNLIGTYSIPYIALIDGITMGGGVGISVHGHYRIATEKTLFAMPETAIGLFPDVGGSYFLPRLIGKLGLYLGLSGHQLKGSDVMKAGIATHYIESSKLPKLYEELTNSTTADNLDSVIIKHTDLMHSQPFSLLPLRSKIDHCFSGNTIEEIVQRLKEDKSDWANNTLENLKKMSPLSLKITKRANDFGSKQSLQDCLKMENRLAAAAIETRVSKDFYEGVRALLVDKDKNPKWNPKTLEEISDDTVNKCFGPLEHIEEEISYLRSRKK", "md5" : "0300fd1eaf020f2ca934d56824e19627", "matches" : [ { "signature" : { "accession" : "cd06558", "name" : "crotonase-like", "description" : "crotonase-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 44, "end" : 233, "sites" : [ { "description" : "oxyanion hole (OAH) forming residues", "numLocations" : 2, "siteLocations" : [ { "start" : 102, "end" : 102, "residue" : "G" }, { "start" : 150, "end" : 150, "residue" : "G" } ] }, { "description" : "substrate binding site", "numLocations" : 15, "siteLocations" : [ { "start" : 63, "end" : 63, "residue" : "L" }, { "start" : 65, "end" : 65, "residue" : "A" }, { "start" : 146, "end" : 146, "residue" : "I" }, { "start" : 103, "end" : 103, "residue" : "D" }, { "start" : 100, "end" : 100, "residue" : "A" }, { "start" : 101, "end" : 101, "residue" : "G" }, { "start" : 149, "end" : 149, "residue" : "G" }, { "start" : 176, "end" : 176, "residue" : "I" }, { "start" : 102, "end" : 102, "residue" : "G" }, { "start" : 150, "end" : 150, "residue" : "G" }, { "start" : 96, "end" : 96, "residue" : "K" }, { "start" : 173, "end" : 173, "residue" : "E" }, { "start" : 172, "end" : 172, "residue" : "P" }, { "start" : 104, "end" : 104, "residue" : "V" }, { "start" : 148, "end" : 148, "residue" : "M" } ] }, { "description" : "trimer interface", "numLocations" : 26, "siteLocations" : [ { "start" : 177, "end" : 177, "residue" : "G" }, { "start" : 186, "end" : 186, "residue" : "Y" }, { "start" : 197, "end" : 197, "residue" : "L" }, { "start" : 161, "end" : 161, "residue" : "R" }, { "start" : 162, "end" : 162, "residue" : "I" }, { "start" : 195, "end" : 195, "residue" : "L" }, { "start" : 218, "end" : 218, "residue" : "T" }, { "start" : 189, "end" : 189, "residue" : "P" }, { "start" : 130, "end" : 130, "residue" : "N" }, { "start" : 200, "end" : 200, "residue" : "G" }, { "start" : 198, "end" : 198, "residue" : "Y" }, { "start" : 194, "end" : 194, "residue" : "K" }, { "start" : 185, "end" : 185, "residue" : "S" }, { "start" : 159, "end" : 159, "residue" : "H" }, { "start" : 183, "end" : 183, "residue" : "G" }, { "start" : 215, "end" : 215, "residue" : "G" }, { "start" : 175, "end" : 175, "residue" : "A" }, { "start" : 176, "end" : 176, "residue" : "I" }, { "start" : 201, "end" : 201, "residue" : "L" }, { "start" : 233, "end" : 233, "residue" : "L" }, { "start" : 138, "end" : 138, "residue" : "P" }, { "start" : 204, "end" : 204, "residue" : "H" }, { "start" : 174, "end" : 174, "residue" : "T" }, { "start" : 190, "end" : 190, "residue" : "R" }, { "start" : 160, "end" : 160, "residue" : "Y" }, { "start" : 187, "end" : 187, "residue" : "F" } ] } ], "evalue" : 1.72127E-53, "score" : 174.286, "location-fragments" : [ { "start" : 44, "end" : 233, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd06558" }, { "signature" : { "accession" : "PTHR43176", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 44, "end" : 382, "hmmStart" : 5, "hmmEnd" : 345, "hmmLength" : 360, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 36, "envelopeEnd" : 393, "location-fragments" : [ { "start" : 44, "end" : 382, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-130, "familyName" : "3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL", "score" : 437.6, "model-ac" : "PTHR43176" }, { "signature" : { "accession" : "PTHR43176:SF3", "name" : "3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 44, "end" : 382, "hmmStart" : 5, "hmmEnd" : 345, "hmmLength" : 360, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 36, "envelopeEnd" : 393, "location-fragments" : [ { "start" : 44, "end" : 382, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-130, "familyName" : "3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL", "score" : 437.6, "model-ac" : "PTHR43176:SF3" }, { "signature" : { "accession" : "G3DSA:3.90.226.40", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 39, "end" : 392, "hmmStart" : 6, "hmmEnd" : 352, "hmmLength" : 363, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-128, "score" : 429.4, "envelopeStart" : 39, "envelopeEnd" : 392, "postProcessed" : true, "location-fragments" : [ { "start" : 39, "end" : 392, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-128, "score" : 429.9, "model-ac" : "3bptA00" }, { "signature" : { "accession" : "SSF52096", "name" : "ClpP/crotonase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029045", "name" : "ClpP/crotonase-like_dom_sf", "description" : "ClpP/crotonase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 43, "end" : 364, "hmmLength" : 310, "location-fragments" : [ { "start" : 285, "end" : 364, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 43, "end" : 223, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.33E-59, "model-ac" : "0050444" }, { "signature" : { "accession" : "PF16113", "name" : "ECH_2", "description" : "Enoyl-CoA hydratase/isomerase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR032259", "name" : "HIBYL-CoA-H", "description" : "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type", "type" : "FAMILY", "goXRefs" : [ { "name" : "3-hydroxyisobutyryl-CoA hydrolase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003860" } ], "pathwayXRefs" : [ { "name" : "Branched-chain amino acid catabolism", "databaseName" : "Reactome", "id" : "R-HSA-70895" } ] } }, "locations" : [ { "start" : 53, "end" : 378, "hmmStart" : 2, "hmmEnd" : 334, "hmmLength" : 334, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.3E-127, "score" : 425.1, "envelopeStart" : 52, "envelopeEnd" : 378, "postProcessed" : true, "location-fragments" : [ { "start" : 53, "end" : 378, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-127, "score" : 425.3, "model-ac" : "PF16113" } ], "xref" : [ { "name" : "XP_018910505.1 PREDICTED: 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial [Bemisia tabaci]", "id" : "XP_018910505.1" } ] },{ "sequence" : "MEEISSASDVDLEDGEIIDDSDSDLSIFNIKELNPLTEKPSSVNSVTGSDILLFPVHSPSPKKKLNKSKENKKVDFDGTKLVIQIPGLADSAKSRGDRPRHKSHHHRRRKKADKIYEDWNRSIDLLTSPKKRKKPVRSSNKYSSCESLSNEWRSSKKTCVEPKQYHVPVEGNPLLAKLLYAGDINPASVILKEINGKNEKPQVINLISDVSSTDLSVDHDVKSPMFSTAHSDVTDGGSDDFVTNQNAKTPSVHHTKLSASSSDIVAASDPLTTYNRNCQNITEPPSSGTLSETAKIFCNSEPLKHTPIIHIDGTSESSVQACEVKDFDTTIAPKNLSQSYLSYNNKSDQNDVYSPETFTPFDYNTLQDSETLELRAALANKSDLVSENYDCIPMSCSEDEDLSSVDSKSDKSEDLKPQQQNNDTDSEEEEELRLRISALKTWLQRKYGKTKPGENQSAFQSPMEGEIEQPQSSLTKIASSSSEKEVSQKNNSPDMLSSHSGPIQSFVDTPLSPSVDSDQSCSSNAAISRSQRTSSVIDRISSPLPVEEIINEQREDKEMDGPQDEADLKKETSVATIDNSLLDEEASENYELALRSLLVSKLLKQKLENSNDLLTESNLINKASSSLISKSPGKISSNSKTSQSSKLIVNSKYRTVNSTKTVAQNLKNSANKSGLIHCDSFQSKYVFNNFYEPPSQVEDSKHLSSISNFKIPVVEKFVIHLSEDSDYDSDESECKTAPHEKGAGSSESSSGNAVKIPMVLPNSKSSSKITESTQQRMVGESCSTTSIHNTGRDKSPVSQTALSDRQNRVTKSSRLQTEKSRRDTLEFQTRKTNSAAITSKLVKTSGADKLAVLSSPRKITSSSSLVSMDGSETESTSVLKEAKNVSNSPSSHEKLGKANSMLISNVLVPVEKKLLKSRLNLLTNLDSMQGCVSSCEENASKCSKSFAKIVQLQKALKMATSEYKTQFKSLKDSLQCYKVQSQKVSSCLGEYAQTQKDCAKAGKQILGPNYKTPNEGMSAMAMKFKLMKEKKLELLNNASIAAEIKKANFSSDASSTTVSAVLKSISEGSAQDKSLDPTAIPTIMVTNADSYGHRKSTSNVSQPGDTSVNVACHKAVEAKTVINASCDSSSVQVSAADSATLIGSSQKIVLGNPEPSSENVSGDTCENKSTALRSNERVGTSSSPQISSPPPLPEALLAMLEVMECEESKKEGVSKCQQKFTKYTPVLSSLSRSSGRDEKYSVDSIICPFNLQGTCRDETCEYKHLPN", "md5" : "ae739e3ccd752d1115c0303a902f0d9d", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 742, "end" : 810, "location-fragments" : [ { "start" : 742, "end" : 810, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1147, "end" : 1192, "location-fragments" : [ { "start" : 1147, "end" : 1192, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 400, "end" : 432, "location-fragments" : [ { "start" : 400, "end" : 432, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1147, "end" : 1185, "location-fragments" : [ { "start" : 1147, "end" : 1185, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 729, "end" : 822, "location-fragments" : [ { "start" : 729, "end" : 822, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50103", "name" : "ZF_C3H1", "description" : "Zinc finger C3H1-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000571", "name" : "Znf_CCCH", "description" : "Zinc finger, CCCH-type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "metal ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046872" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1241, "end" : 1267, "score" : 9.207, "alignment" : "SVDSIICPFNLQGTCR-DETCEYKHLPN", "location-fragments" : [ { "start" : 1241, "end" : 1267, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50103" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 450, "end" : 527, "location-fragments" : [ { "start" : 450, "end" : 527, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 401, "end" : 432, "location-fragments" : [ { "start" : 401, "end" : 432, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 447, "end" : 527, "location-fragments" : [ { "start" : 447, "end" : 527, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 87, "end" : 113, "location-fragments" : [ { "start" : 87, "end" : 113, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 38, "end" : 71, "location-fragments" : [ { "start" : 38, "end" : 71, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910143.1 PREDICTED: flocculation protein FLO10-like [Bemisia tabaci]", "id" : "XP_018910143.1" } ] },{ "sequence" : "MEQLDKLLQAAILFFVILSTINIEALYTYGAASDIFGEGKSDKEILDNLLLATRYDKRLLPPVVGTLTVNMSVLLLSLASPDESSLKYEVEFLLQQQWYDPRLTYSNQSKYDFLNAIHHHSDIWLPDTYFIMHGDFKDPLIPVHFALRIYRNGTVNYLMRRHLILSCQGRLHIFPFDDPLCSFAMESISYEQSAITYVWKNDEDTLRKSPSLTTLNAYLIQNQTIACPTKASWRGNYSCLKVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVAQRLPAVLSRIGMVLATPLARRKEPPHPIRVAKTIDVIARITFPVAYSIFLIFFFIHYKGFQNNAEGIIIDSEPDAQPLKMPQPENTASTHQSNFDHQTTSHLSPFSSDTTPH", "md5" : "e224e0f0fb8f6d29c84ea9b555c68a56", "matches" : [ { "signature" : { "accession" : "SSF63712", "name" : "Nicotinic receptor ligand binding domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036734", "name" : "Neur_chan_lig-bd_sf", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 249, "hmmLength" : 205, "location-fragments" : [ { "start" : 42, "end" : 249, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.92E-39, "model-ac" : "0038932" }, { "signature" : { "accession" : "PF02932", "name" : "Neur_chan_memb", "description" : "Neurotransmitter-gated ion-channel transmembrane region", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006029", "name" : "Neurotrans-gated_channel_TM", "description" : "Neurotransmitter-gated ion-channel transmembrane domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 258, "end" : 362, "hmmStart" : 2, "hmmEnd" : 106, "hmmLength" : 238, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-13, "score" : 51.3, "envelopeStart" : 257, "envelopeEnd" : 365, "postProcessed" : true, "location-fragments" : [ { "start" : 258, "end" : 362, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-14, "score" : 54.4, "model-ac" : "PF02932" }, { "signature" : { "accession" : "G3DSA:2.70.170.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036734", "name" : "Neur_chan_lig-bd_sf", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 247, "hmmStart" : 9, "hmmEnd" : 218, "hmmLength" : 219, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.1E-43, "score" : 151.0, "envelopeStart" : 37, "envelopeEnd" : 249, "postProcessed" : true, "location-fragments" : [ { "start" : 37, "end" : 247, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.8E-44, "score" : 151.4, "model-ac" : "5cfbA01" }, { "signature" : { "accession" : "SSF90112", "name" : "Neurotransmitter-gated ion-channel transmembrane pore", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036719", "name" : "Neuro-gated_channel_TM_sf", "description" : "Neurotransmitter-gated ion-channel transmembrane domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 252, "end" : 414, "hmmLength" : 227, "location-fragments" : [ { "start" : 252, "end" : 414, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.44E-25, "model-ac" : "0041810" }, { "signature" : { "accession" : "cd19049", "name" : "LGIC_TM_anion", "description" : "LGIC_TM_anion", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 252, "end" : 410, "sites" : [ { "description" : "pentamer interface", "numLocations" : 35, "siteLocations" : [ { "start" : 298, "end" : 298, "residue" : "N" }, { "start" : 309, "end" : 309, "residue" : "N" }, { "start" : 395, "end" : 395, "residue" : "R" }, { "start" : 332, "end" : 332, "residue" : "V" }, { "start" : 325, "end" : 325, "residue" : "Y" }, { "start" : 278, "end" : 278, "residue" : "A" }, { "start" : 279, "end" : 279, "residue" : "V" }, { "start" : 291, "end" : 291, "residue" : "L" }, { "start" : 321, "end" : 321, "residue" : "M" }, { "start" : 267, "end" : 267, "residue" : "S" }, { "start" : 274, "end" : 274, "residue" : "L" }, { "start" : 264, "end" : 264, "residue" : "L" }, { "start" : 281, "end" : 281, "residue" : "A" }, { "start" : 328, "end" : 328, "residue" : "L" }, { "start" : 336, "end" : 336, "residue" : "Y" }, { "start" : 270, "end" : 270, "residue" : "I" }, { "start" : 301, "end" : 301, "residue" : "R" }, { "start" : 263, "end" : 263, "residue" : "I" }, { "start" : 302, "end" : 302, "residue" : "S" }, { "start" : 285, "end" : 285, "residue" : "I" }, { "start" : 255, "end" : 255, "residue" : "T" }, { "start" : 266, "end" : 266, "residue" : "T" }, { "start" : 284, "end" : 284, "residue" : "M" }, { "start" : 292, "end" : 292, "residue" : "N" }, { "start" : 256, "end" : 256, "residue" : "T" }, { "start" : 283, "end" : 283, "residue" : "V" }, { "start" : 288, "end" : 288, "residue" : "T" }, { "start" : 299, "end" : 299, "residue" : "G" }, { "start" : 335, "end" : 335, "residue" : "N" }, { "start" : 273, "end" : 273, "residue" : "W" }, { "start" : 280, "end" : 280, "residue" : "P" }, { "start" : 252, "end" : 252, "residue" : "F" }, { "start" : 287, "end" : 287, "residue" : "V" }, { "start" : 310, "end" : 310, "residue" : "L" }, { "start" : 275, "end" : 275, "residue" : "E" } ] } ], "evalue" : 7.06935E-33, "score" : 118.709, "location-fragments" : [ { "start" : 252, "end" : 410, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd19049" }, { "signature" : { "accession" : "PF02931", "name" : "Neur_chan_LBD", "description" : "Neurotransmitter-gated ion-channel ligand binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006202", "name" : "Neur_chan_lig-bd", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 223, "hmmStart" : 3, "hmmEnd" : 181, "hmmLength" : 217, "hmmBounds" : "INCOMPLETE", "evalue" : 2.7E-31, "score" : 108.7, "envelopeStart" : 42, "envelopeEnd" : 250, "postProcessed" : true, "location-fragments" : [ { "start" : 44, "end" : 223, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-31, "score" : 109.2, "model-ac" : "PF02931" }, { "signature" : { "accession" : "PTHR18945:SF819", "name" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 70, "end" : 354, "hmmStart" : 110, "hmmEnd" : 394, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 64, "envelopeEnd" : 374, "location-fragments" : [ { "start" : 70, "end" : 354, "dc-status" : "CONTINUOUS" } ] }, { "start" : 23, "end" : 63, "hmmStart" : 38, "hmmEnd" : 78, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 72, "location-fragments" : [ { "start" : 23, "end" : 63, "dc-status" : "CONTINUOUS" } ] }, { "start" : 376, "end" : 411, "hmmStart" : 459, "hmmEnd" : 494, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 371, "envelopeEnd" : 417, "location-fragments" : [ { "start" : 376, "end" : 411, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-152, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 511.1, "model-ac" : "PTHR18945:SF819" }, { "signature" : { "accession" : "PTHR18945", "name" : "NEUROTRANSMITTER GATED ION CHANNEL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 376, "end" : 411, "hmmStart" : 459, "hmmEnd" : 494, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 371, "envelopeEnd" : 417, "location-fragments" : [ { "start" : 376, "end" : 411, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-152, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 511.1, "model-ac" : "PTHR18945" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 437, "end" : 468, "location-fragments" : [ { "start" : 437, "end" : 468, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 428, "end" : 468, "location-fragments" : [ { "start" : 428, "end" : 468, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PR00253", "name" : "GABAARECEPTR", "description" : "Gamma-aminobutyric acid A (GABAA) receptor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR006028", "name" : "GABAA/Glycine_rcpt", "description" : "Gamma-aminobutyric acid A receptor/Glycine receptor alpha", "type" : "FAMILY", "goXRefs" : [ { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 313, "end" : 334, "pvalue" : 1.28E-8, "score" : 35.36, "motifNumber" : 3, "location-fragments" : [ { "start" : 313, "end" : 334, "dc-status" : "CONTINUOUS" } ] }, { "start" : 393, "end" : 413, "pvalue" : 2.7E-6, "score" : 34.22, "motifNumber" : 4, "location-fragments" : [ { "start" : 393, "end" : 413, "dc-status" : "CONTINUOUS" } ] }, { "start" : 253, "end" : 273, "pvalue" : 9.85E-6, "score" : 29.84, "motifNumber" : 1, "location-fragments" : [ { "start" : 253, "end" : 273, "dc-status" : "CONTINUOUS" } ] }, { "start" : 279, "end" : 300, "pvalue" : 5.49E-10, "score" : 43.64, "motifNumber" : 2, "location-fragments" : [ { "start" : 279, "end" : 300, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-22, "graphscan" : "iIII", "model-ac" : "PR00253" }, { "signature" : { "accession" : "cd18987", "name" : "LGIC_ECD_anion", "description" : "LGIC_ECD_anion", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 67, "end" : 249, "sites" : [ { "description" : "pentamer interface", "numLocations" : 30, "siteLocations" : [ { "start" : 160, "end" : 160, "residue" : "R" }, { "start" : 249, "end" : 249, "residue" : "D" }, { "start" : 148, "end" : 148, "residue" : "R" }, { "start" : 134, "end" : 134, "residue" : "G" }, { "start" : 136, "end" : 136, "residue" : "F" }, { "start" : 93, "end" : 93, "residue" : "L" }, { "start" : 126, "end" : 126, "residue" : "P" }, { "start" : 144, "end" : 144, "residue" : "H" }, { "start" : 131, "end" : 131, "residue" : "I" }, { "start" : 85, "end" : 85, "residue" : "S" }, { "start" : 188, "end" : 188, "residue" : "I" }, { "start" : 139, "end" : 139, "residue" : "P" }, { "start" : 158, "end" : 158, "residue" : "L" }, { "start" : 79, "end" : 79, "residue" : "A" }, { "start" : 130, "end" : 130, "residue" : "F" }, { "start" : 77, "end" : 77, "residue" : "S" }, { "start" : 128, "end" : 128, "residue" : "T" }, { "start" : 96, "end" : 96, "residue" : "Q" }, { "start" : 145, "end" : 145, "residue" : "F" }, { "start" : 115, "end" : 115, "residue" : "N" }, { "start" : 117, "end" : 117, "residue" : "I" }, { "start" : 86, "end" : 86, "residue" : "L" }, { "start" : 138, "end" : 138, "residue" : "D" }, { "start" : 95, "end" : 95, "residue" : "Q" }, { "start" : 127, "end" : 127, "residue" : "D" }, { "start" : 118, "end" : 118, "residue" : "H" }, { "start" : 159, "end" : 159, "residue" : "M" }, { "start" : 80, "end" : 80, "residue" : "S" }, { "start" : 129, "end" : 129, "residue" : "Y" }, { "start" : 146, "end" : 146, "residue" : "A" } ] } ], "evalue" : 2.02295E-47, "score" : 159.767, "location-fragments" : [ { "start" : 67, "end" : 249, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18987" }, { "signature" : { "accession" : "PTHR18945", "name" : "NEUROTRANSMITTER GATED ION CHANNEL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 70, "end" : 354, "hmmStart" : 110, "hmmEnd" : 394, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 64, "envelopeEnd" : 374, "location-fragments" : [ { "start" : 70, "end" : 354, "dc-status" : "CONTINUOUS" } ] }, { "start" : 23, "end" : 63, "hmmStart" : 38, "hmmEnd" : 78, "hmmLength" : 500, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 72, "location-fragments" : [ { "start" : 23, "end" : 63, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-152, "familyName" : "PH-SENSITIVE CHLORIDE CHANNEL, ISOFORM N", "score" : 511.1, "model-ac" : "PTHR18945" } ], "xref" : [ { "name" : "XP_018910353.1 PREDICTED: glycine receptor subunit alpha-4 isoform X8 [Bemisia tabaci]", "id" : "XP_018910353.1" } ] },{ "sequence" : "MTEALSSSSAGERRLKELEALFLGGPIQGRGQCFSIETLLDILLVLYDECTNSSLRREKTVSEFIEFVKPVATCVKNLRLSRDDFEMVKVIGRGAFGEVFVVRMKGSEKVFAMKILNKWEMLRRAEIACFQEERDVLVYGDRRWITNLHYAFQDEANLYLVMDYYCGGDLLTLLSKFEDRLPEDMARFYIAEMVLAISSVHDLRYVHRDIKPDNVLLDANGHIRLADFGSCLKLSEDGTVQSNVAVGTPDYISPEILRAMEDGQGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKNCFDFPSDLPVEVTNDAKDLMKRLICSAEYRLGQNGVEDFKNHAWFLGIDWSSLRDSTAPYLPEVSSPTDTSNFDVDDMDIRTSDSVPPTASNPAFTGLHLPFVGFTFTQGSRVGDLGCITFSDSNIRMSAGGKRMRLHEDQLDCKAEPLNNARKISPTSESTGTNLRKLQDEINTLTKRNCELESELQDLEGHERVRELEKLMRLLKQEKEEVNKEKVEVEEKLKLQEKELKDAVSQKKIAMAEYSEVSDKLSDLRQQKQKLSRIVRDKEEELEQAMQKIDSLRQDMRRGEKLRRELEARIDEAMQEATKERKLRERSEEYCNQLKAEWKQLKERRDTGSGDGSSAISQHNIQEINRLKTELETLEVEYSDNLSQQQARHREEINNLREQLLEAEARKEVLEKELNAGRLQETEMGNKKESIAQWEAQISEIIQWVNDEKDARGYLQALATKMTEELEYLKHTAVSTNTVDKSWRNRRSQKLEKMELLNLQSSLQSEIQAKQTIGDELSRTRAELIAAQKELREFHQRFDNLVVDVKRKEIQLKELQARLDSGEGFERKNLVLERPGSQMSYLDHFLKESSVTRQLRDSITSEEGNLDDNQTLSVASSKTNLSDMNMEQSSLKLQPRVLSSNMMIAKSHQFLIRTFSAPTKCNHCTSLMIGLTRQGVVCEVCGFACHTTCCDKVPIACPVPPDQTKRPLGIDPTRGIGTAYEGYVKVPRAGGVKKGWVRQFVVVCDFKLFLYDISADRNALPSVQVSQVLDMRDEHFSVSSVRESDVIHAMKKDIPCIFRITTSLLEPSELQNHTLMLADTESEKSKWVVALSELHRILKRNNLPNTTVFKAKQVMDSTLRAVMSGAIVDPDRLVIGTEDGLFCLDLDHSEMARVGEGKKVFEMEYIEKEQLLLVLSGKQRHVRLIPVRALDGDEVEWIKVTESKGCITFAVGQLSRNVHCLCVAIKRQNTSQIIIYEITRTRQRHKRMREVMIPTQVQTVQVLSEARLCVGYQSGFSIYNISGDHLAMPLIGTDNPVASFLSYSNSEALKCIELPRGEFLLVFQTLGIYVDSQGRKSRDKEIMYPAYPIAVSYSDGYLLVFSEIHVDVFNVETGDWVQTLNTKRALPLDTHGSLAICLVNDLTHLIYLHNLHQRELLNLTTFDASGREIPRTRRRFSLREGNRASRAPDRRSKMISAPSNFNHISHMGPGDGIQVQRLLDLPTTIETADNAPSPYPKVLHAPPVPLKMSHPPPRHPPPRIPMHPPHNGSSIRRAPAPPRPTPDSVSLYHDFKDQNTSPRHSIASNNSSNPSTPPSPGRDSSCDS", "md5" : "f4ccc073f48800048ad9fc24e55c4014", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 473, "end" : 493, "location-fragments" : [ { "start" : 473, "end" : 493, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PR00008", "name" : "DAGPEDOMAIN", "description" : "Diacylglycerol/phorbol-ester binding signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR020454", "name" : "DAG/PE-bd", "description" : "Diacylglycerol/phorbol-ester binding", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 959, "end" : 968, "pvalue" : 0.00713, "score" : 40.99, "motifNumber" : 2, "location-fragments" : [ { "start" : 959, "end" : 968, "dc-status" : "CONTINUOUS" } ] }, { "start" : 984, "end" : 996, "pvalue" : 0.0132, "score" : 36.1, "motifNumber" : 4, "location-fragments" : [ { "start" : 984, "end" : 996, "dc-status" : "CONTINUOUS" } ] }, { "start" : 972, "end" : 983, "pvalue" : 0.00184, "score" : 43.23, "motifNumber" : 3, "location-fragments" : [ { "start" : 972, "end" : 983, "dc-status" : "CONTINUOUS" } ] }, { "start" : 943, "end" : 957, "pvalue" : 1.01E-4, "score" : 35.31, "motifNumber" : 1, "location-fragments" : [ { "start" : 943, "end" : 957, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-5, "graphscan" : "IIII", "model-ac" : "PR00008" }, { "signature" : { "accession" : "PTHR22988:SF66", "name" : "SERINE/THREONINE-PROTEIN KINASE GENGHIS KHAN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 720, "end" : 1533, "hmmStart" : 725, "hmmEnd" : 1527, "hmmLength" : 1548, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 715, "envelopeEnd" : 1610, "location-fragments" : [ { "start" : 720, "end" : 1533, "dc-status" : "CONTINUOUS" } ] }, { "start" : 12, "end" : 714, "hmmStart" : 5, "hmmEnd" : 658, "hmmLength" : 1548, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 721, "location-fragments" : [ { "start" : 12, "end" : 714, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "SERINE/THREONINE-PROTEIN KINASE GENGHIS KHAN", "score" : 2097.0, "model-ac" : "PTHR22988:SF66" }, { "signature" : { "accession" : "cd05597", "name" : "STKc_DMPK_like", "description" : "STKc_DMPK_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 83, "end" : 415, "sites" : [ { "description" : "ATP binding site", "numLocations" : 20, "siteLocations" : [ { "start" : 164, "end" : 164, "residue" : "Y" }, { "start" : 92, "end" : 92, "residue" : "G" }, { "start" : 114, "end" : 114, "residue" : "K" }, { "start" : 163, "end" : 163, "residue" : "D" }, { "start" : 227, "end" : 227, "residue" : "D" }, { "start" : 112, "end" : 112, "residue" : "A" }, { "start" : 165, "end" : 165, "residue" : "Y" }, { "start" : 169, "end" : 169, "residue" : "D" }, { "start" : 91, "end" : 91, "residue" : "I" }, { "start" : 95, "end" : 95, "residue" : "A" }, { "start" : 216, "end" : 216, "residue" : "L" }, { "start" : 209, "end" : 209, "residue" : "D" }, { "start" : 214, "end" : 214, "residue" : "N" }, { "start" : 146, "end" : 146, "residue" : "T" }, { "start" : 211, "end" : 211, "residue" : "K" }, { "start" : 94, "end" : 94, "residue" : "G" }, { "start" : 213, "end" : 213, "residue" : "D" }, { "start" : 93, "end" : 93, "residue" : "R" }, { "start" : 99, "end" : 99, "residue" : "V" }, { "start" : 226, "end" : 226, "residue" : "A" } ] }, { "description" : "polypeptide substrate binding site", "numLocations" : 16, "siteLocations" : [ { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 169, "end" : 169, "residue" : "D" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 95, "end" : 95, "residue" : "A" }, { "start" : 249, "end" : 249, "residue" : "P" }, { "start" : 291, "end" : 291, "residue" : "Y" }, { "start" : 282, "end" : 282, "residue" : "E" }, { "start" : 245, "end" : 245, "residue" : "A" }, { "start" : 288, "end" : 288, "residue" : "T" }, { "start" : 230, "end" : 230, "residue" : "S" }, { "start" : 209, "end" : 209, "residue" : "D" }, { "start" : 250, "end" : 250, "residue" : "D" }, { "start" : 171, "end" : 171, "residue" : "L" }, { "start" : 211, "end" : 211, "residue" : "K" }, { "start" : 213, "end" : 213, "residue" : "D" }, { "start" : 248, "end" : 248, "residue" : "T" } ] }, { "description" : "activation loop (A-loop)", "numLocations" : 23, "siteLocations" : [ { "start" : 234, "end" : 234, "residue" : "L" }, { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 227, "end" : 227, "residue" : "D" }, { "start" : 228, "end" : 228, "residue" : "F" }, { "start" : 236, "end" : 236, "residue" : "E" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 239, "end" : 239, "residue" : "T" }, { "start" : 249, "end" : 249, "residue" : "P" }, { "start" : 242, "end" : 242, "residue" : "S" }, { "start" : 229, "end" : 229, "residue" : "G" }, { "start" : 240, "end" : 240, "residue" : "V" }, { "start" : 245, "end" : 245, "residue" : "A" }, { "start" : 235, "end" : 235, "residue" : "S" }, { "start" : 230, "end" : 230, "residue" : "S" }, { "start" : 232, "end" : 232, "residue" : "L" }, { "start" : 244, "end" : 244, "residue" : "V" }, { "start" : 241, "end" : 241, "residue" : "Q" }, { "start" : 243, "end" : 243, "residue" : "N" }, { "start" : 250, "end" : 250, "residue" : "D" }, { "start" : 231, "end" : 231, "residue" : "C" }, { "start" : 226, "end" : 226, "residue" : "A" }, { "start" : 233, "end" : 233, "residue" : "K" }, { "start" : 248, "end" : 248, "residue" : "T" } ] }, { "description" : "active site", "numLocations" : 31, "siteLocations" : [ { "start" : 92, "end" : 92, "residue" : "G" }, { "start" : 114, "end" : 114, "residue" : "K" }, { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 163, "end" : 163, "residue" : "D" }, { "start" : 227, "end" : 227, "residue" : "D" }, { "start" : 162, "end" : 162, "residue" : "M" }, { "start" : 165, "end" : 165, "residue" : "Y" }, { "start" : 95, "end" : 95, "residue" : "A" }, { "start" : 249, "end" : 249, "residue" : "P" }, { "start" : 291, "end" : 291, "residue" : "Y" }, { "start" : 245, "end" : 245, "residue" : "A" }, { "start" : 209, "end" : 209, "residue" : "D" }, { "start" : 250, "end" : 250, "residue" : "D" }, { "start" : 214, "end" : 214, "residue" : "N" }, { "start" : 146, "end" : 146, "residue" : "T" }, { "start" : 211, "end" : 211, "residue" : "K" }, { "start" : 94, "end" : 94, "residue" : "G" }, { "start" : 99, "end" : 99, "residue" : "V" }, { "start" : 226, "end" : 226, "residue" : "A" }, { "start" : 112, "end" : 112, "residue" : "A" }, { "start" : 169, "end" : 169, "residue" : "D" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 91, "end" : 91, "residue" : "I" }, { "start" : 282, "end" : 282, "residue" : "E" }, { "start" : 288, "end" : 288, "residue" : "T" }, { "start" : 230, "end" : 230, "residue" : "S" }, { "start" : 216, "end" : 216, "residue" : "L" }, { "start" : 171, "end" : 171, "residue" : "L" }, { "start" : 213, "end" : 213, "residue" : "D" }, { "start" : 93, "end" : 93, "residue" : "R" }, { "start" : 248, "end" : 248, "residue" : "T" } ] }, { "description" : "hydrophobic motif (HM)", "numLocations" : 6, "siteLocations" : [ { "start" : 409, "end" : 409, "residue" : "F" }, { "start" : 414, "end" : 414, "residue" : "F" }, { "start" : 412, "end" : 412, "residue" : "F" }, { "start" : 410, "end" : 410, "residue" : "V" }, { "start" : 413, "end" : 413, "residue" : "T" }, { "start" : 411, "end" : 411, "residue" : "G" } ] } ], "evalue" : 0.0, "score" : 734.153, "location-fragments" : [ { "start" : 83, "end" : 415, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd05597" }, { "signature" : { "accession" : "cd00132", "name" : "CRIB", "description" : "CRIB", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1491, "end" : 1527, "sites" : [ { "description" : "GTPase interaction site", "numLocations" : 7, "siteLocations" : [ { "start" : 1519, "end" : 1519, "residue" : "L" }, { "start" : 1496, "end" : 1496, "residue" : "P" }, { "start" : 1493, "end" : 1493, "residue" : "I" }, { "start" : 1501, "end" : 1501, "residue" : "H" }, { "start" : 1523, "end" : 1523, "residue" : "I" }, { "start" : 1504, "end" : 1504, "residue" : "H" }, { "start" : 1499, "end" : 1499, "residue" : "F" } ] } ], "evalue" : 1.64252E-8, "score" : 49.7445, "location-fragments" : [ { "start" : 1491, "end" : 1527, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00132" }, { "signature" : { "accession" : "PS50108", "name" : "CRIB", "description" : "CRIB domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000095", "name" : "CRIB_dom", "description" : "CRIB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1493, "end" : 1506, "score" : 8.837, "alignment" : "ISAPSNFNHISHMG", "location-fragments" : [ { "start" : 1493, "end" : 1506, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50108" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 655, "end" : 718, "location-fragments" : [ { "start" : 655, "end" : 718, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR22988", "name" : "MYOTONIC DYSTROPHY S/T KINASE-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 720, "end" : 1533, "hmmStart" : 725, "hmmEnd" : 1527, "hmmLength" : 1548, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 715, "envelopeEnd" : 1610, "location-fragments" : [ { "start" : 720, "end" : 1533, "dc-status" : "CONTINUOUS" } ] }, { "start" : 12, "end" : 714, "hmmStart" : 5, "hmmEnd" : 658, "hmmLength" : 1548, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 721, "location-fragments" : [ { "start" : 12, "end" : 714, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "SERINE/THREONINE-PROTEIN KINASE GENGHIS KHAN", "score" : 2097.0, "model-ac" : "PTHR22988" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 61, "end" : 403, "hmmLength" : 353, "location-fragments" : [ { "start" : 61, "end" : 403, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.61E-80, "model-ac" : "0040180" }, { "signature" : { "accession" : "PS50081", "name" : "ZF_DAG_PE_2", "description" : "Zinc finger phorbol-ester/DAG-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 945, "end" : 995, "score" : 14.189, "alignment" : "SHQFLIRTFSAPTKCNHCTSLMIGLTRQGVVCEVCGFACHTTCCDKVPIAC", "location-fragments" : [ { "start" : 945, "end" : 995, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50081" }, { "signature" : { "accession" : "SM00036", "name" : "nik_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001180", "name" : "CNH_dom", "description" : "Citron homology (CNH) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1157, "end" : 1448, "hmmStart" : 1, "hmmEnd" : 375, "hmmLength" : 375, "hmmBounds" : "COMPLETE", "evalue" : 6.7E-21, "score" : 85.4, "location-fragments" : [ { "start" : 1157, "end" : 1448, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-21, "score" : 85.4, "model-ac" : "SM00036" }, { "signature" : { "accession" : "PS50003", "name" : "PH_DOMAIN", "description" : "PH domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001849", "name" : "PH_domain", "description" : "Pleckstrin homology domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1015, "end" : 1134, "score" : 9.125, "alignment" : "GTAYEGYVKVPRAGgVKKGWVRQFVVVCDFKLFLYDISadrNALPSVQVSQVLDMRDEHFSVSSVRESDVihamkkdIPCIFRITTSLLEpselqNHTLMLADTESEKSKWVVALSELHR", "location-fragments" : [ { "start" : 1015, "end" : 1134, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50003" }, { "signature" : { "accession" : "PS51285", "name" : "AGC_KINASE_CTER", "description" : "AGC-kinase C-terminal domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000961", "name" : "AGC-kinase_C", "description" : "AGC-kinase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein serine/threonine kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004674" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 353, "end" : 424, "score" : 12.7, "alignment" : "LGIDWSSL--RDSTAPYLPEVSSPTDTSNFdvDDMDIRTSDSVPPTASNPAFTGLHLPFVGFTFTQGSRVGDLG", "location-fragments" : [ { "start" : 353, "end" : 424, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51285" }, { "signature" : { "accession" : "SM00133", "name" : "pkinase_C_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000961", "name" : "AGC-kinase_C", "description" : "AGC-kinase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein serine/threonine kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004674" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 353, "end" : 416, "hmmStart" : 1, "hmmEnd" : 79, "hmmLength" : 79, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-7, "score" : 40.6, "location-fragments" : [ { "start" : 353, "end" : 416, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-7, "score" : 40.6, "model-ac" : "SM00133" }, { "signature" : { "accession" : "SM00109", "name" : "c1_12", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 946, "end" : 995, "hmmStart" : 1, "hmmEnd" : 61, "hmmLength" : 61, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-12, "score" : 57.7, "location-fragments" : [ { "start" : 946, "end" : 995, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-12, "score" : 57.7, "model-ac" : "SM00109" }, { "signature" : { "accession" : "PF00130", "name" : "C1_1", "description" : "Phorbol esters/diacylglycerol binding domain (C1 domain)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 946, "end" : 996, "hmmStart" : 1, "hmmEnd" : 51, "hmmLength" : 53, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.9E-11, "score" : 42.7, "envelopeStart" : 946, "envelopeEnd" : 997, "postProcessed" : true, "location-fragments" : [ { "start" : 946, "end" : 996, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-11, "score" : 43.9, "model-ac" : "PF00130" }, { "signature" : { "accession" : "G3DSA:1.10.510.10", "name" : "Transferase(Phosphotransferase) domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 171, "end" : 374, "hmmStart" : 3, "hmmEnd" : 363, "hmmLength" : 363, "hmmBounds" : "INCOMPLETE", "evalue" : 8.6E-187, "score" : 622.2, "envelopeStart" : 16, "envelopeEnd" : 382, "postProcessed" : true, "location-fragments" : [ { "start" : 171, "end" : 374, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-187, "score" : 623.8, "model-ac" : "3tkuA02" }, { "signature" : { "accession" : "SM00220", "name" : "serkin_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 85, "end" : 352, "hmmStart" : 1, "hmmEnd" : 231, "hmmLength" : 231, "hmmBounds" : "COMPLETE", "evalue" : 3.2E-81, "score" : 285.8, "location-fragments" : [ { "start" : 85, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-81, "score" : 285.8, "model-ac" : "SM00220" }, { "signature" : { "accession" : "PS00107", "name" : "PROTEIN_KINASE_ATP", "description" : "Protein kinases ATP-binding region signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017441", "name" : "Protein_kinase_ATP_BS", "description" : "Protein kinase, ATP binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 91, "end" : 114, "level" : "STRONG", "cigarAlignment" : "10M1I1M8I4M", "alignment" : "IGRGAFGEVFvVrmkgsekvFAMK", "location-fragments" : [ { "start" : 91, "end" : 114, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00107" }, { "signature" : { "accession" : "PF00780", "name" : "CNH", "description" : "CNH domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001180", "name" : "CNH_dom", "description" : "Citron homology (CNH) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1166, "end" : 1428, "hmmStart" : 5, "hmmEnd" : 277, "hmmLength" : 279, "hmmBounds" : "INCOMPLETE", "evalue" : 7.6E-62, "score" : 209.3, "envelopeStart" : 1163, "envelopeEnd" : 1430, "postProcessed" : true, "location-fragments" : [ { "start" : 1166, "end" : 1428, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-62, "score" : 210.3, "model-ac" : "PF00780" }, { "signature" : { "accession" : "PF00433", "name" : "Pkinase_C", "description" : "Protein kinase C terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR017892", "name" : "Pkinase_C", "description" : "Protein kinase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein serine/threonine kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004674" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 371, "end" : 414, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 6.9E-5, "score" : 23.5, "envelopeStart" : 371, "envelopeEnd" : 414, "postProcessed" : true, "location-fragments" : [ { "start" : 371, "end" : 414, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-5, "score" : 24.8, "model-ac" : "PF00433" }, { "signature" : { "accession" : "SSF50729", "name" : "PH domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 1014, "end" : 1135, "hmmLength" : 123, "location-fragments" : [ { "start" : 1014, "end" : 1135, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.83E-9, "model-ac" : "0050619" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1522, "end" : 1622, "location-fragments" : [ { "start" : 1522, "end" : 1622, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 503, "end" : 642, "location-fragments" : [ { "start" : 503, "end" : 642, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "cd01243", "name" : "PH_MRCK", "description" : "PH_MRCK", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1005, "end" : 1139, "sites" : [ ], "evalue" : 3.80002E-83, "score" : 266.47, "location-fragments" : [ { "start" : 1005, "end" : 1139, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01243" }, { "signature" : { "accession" : "PS50219", "name" : "CNH", "description" : "Citron homology (CNH) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001180", "name" : "CNH_dom", "description" : "Citron homology (CNH) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1157, "end" : 1433, "score" : 23.8, "alignment" : "LRAVMSGAIVDPDRLVIGTEDGLFCL----DLD---HSEMARVGEGKKVFEMEYIEKEQLLLVLSgkQRHVRLIPVRALDG-DEVEWIKVTESKGCITFAVGQLSRNVhCLCVAIKRQNTSQIIIYEItRTRQRHKRMREVMIPTQVQTVQVLSEARLCVGYQSGFSIYNISgDHLAMPLIGTDNPVASflSYSNSEALKCIELPRGEFLLVFQTLGIYVDSQGRKSRDK-EIMYPAYPIAVSYSDGYLLVFSEIHVDVFNVETGDWVQTLNTKRALPLDTHGSLA", "location-fragments" : [ { "start" : 1157, "end" : 1433, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50219" }, { "signature" : { "accession" : "G3DSA:3.30.60.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 940, "end" : 1009, "hmmStart" : 7, "hmmEnd" : 67, "hmmLength" : 73, "hmmBounds" : "COMPLETE", "evalue" : 2.2E-17, "score" : 64.5, "envelopeStart" : 940, "envelopeEnd" : 1009, "postProcessed" : true, "location-fragments" : [ { "start" : 940, "end" : 1009, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-17, "score" : 65.5, "model-ac" : "3cxlA02" }, { "signature" : { "accession" : "PS00479", "name" : "ZF_DAG_PE_1", "description" : "Zinc finger phorbol-ester/DAG-type signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 946, "end" : 995, "level" : "STRONG", "cigarAlignment" : "1M1I1M10I1M2I1M3I1M9I1M2I1M4I1M2I1M7I1M", "alignment" : "HqFlirtfsaptkCnhCtslMigltrqgvvCevCgfacHttCcdkvpiaC", "location-fragments" : [ { "start" : 946, "end" : 995, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00479" }, { "signature" : { "accession" : "PS00108", "name" : "PROTEIN_KINASE_ST", "description" : "Serine/Threonine protein kinases active-site signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR008271", "name" : "Ser/Thr_kinase_AS", "description" : "Serine/threonine-protein kinase, active site", "type" : "ACTIVE_SITE", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 205, "end" : 217, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I3M2I4M", "alignment" : "YvHrDIKpdNVLL", "location-fragments" : [ { "start" : 205, "end" : 217, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00108" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 815, "end" : 856, "location-fragments" : [ { "start" : 815, "end" : 856, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "SM00233", "name" : "PH_update", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001849", "name" : "PH_domain", "description" : "Pleckstrin homology domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1016, "end" : 1136, "hmmStart" : 1, "hmmEnd" : 82, "hmmLength" : 82, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-6, "score" : 37.1, "location-fragments" : [ { "start" : 1016, "end" : 1136, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-6, "score" : 37.1, "model-ac" : "SM00233" }, { "signature" : { "accession" : "SM00285", "name" : "PBD_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000095", "name" : "CRIB_dom", "description" : "CRIB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1493, "end" : 1530, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 4.6E-7, "score" : 39.5, "location-fragments" : [ { "start" : 1493, "end" : 1530, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-7, "score" : 39.5, "model-ac" : "SM00285" }, { "signature" : { "accession" : "PF15796", "name" : "KELK", "description" : "KELK-motif containing domain of MRCK Ser/Thr protein kinase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR031597", "name" : "KELK", "description" : "KELK-motif containing domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Thermogenesis", "databaseName" : "KEGG", "id" : "04714+2.7.11.1" }, { "name" : "Human papillomavirus infection", "databaseName" : "KEGG", "id" : "05165+2.7.11.1" }, { "name" : "Human cytomegalovirus infection", "databaseName" : "KEGG", "id" : "05163+2.7.11.1" }, { "name" : "mTOR signaling pathway", "databaseName" : "KEGG", "id" : "04150+2.7.11.1" }, { "name" : "Relaxin signaling pathway", "databaseName" : "KEGG", "id" : "04926+2.7.11.1" }, { "name" : "Human immunodeficiency virus 1 infection", "databaseName" : "KEGG", "id" : "05170+2.7.11.1" }, { "name" : "PI3K-Akt signaling pathway", "databaseName" : "KEGG", "id" : "04151+2.7.11.1" } ] } }, "locations" : [ { "start" : 502, "end" : 581, "hmmStart" : 1, "hmmEnd" : 80, "hmmLength" : 80, "hmmBounds" : "COMPLETE", "evalue" : 2.6E-28, "score" : 98.3, "envelopeStart" : 502, "envelopeEnd" : 581, "postProcessed" : true, "location-fragments" : [ { "start" : 502, "end" : 581, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-28, "score" : 98.3, "model-ac" : "PF15796" }, { "signature" : { "accession" : "G3DSA:2.30.29.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011993", "name" : "PH-like_dom_sf", "description" : "PH-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1017, "end" : 1134, "hmmStart" : 3, "hmmEnd" : 111, "hmmLength" : 117, "hmmBounds" : "COMPLETE", "evalue" : 4.8E-42, "score" : 144.9, "envelopeStart" : 1017, "envelopeEnd" : 1134, "postProcessed" : true, "location-fragments" : [ { "start" : 1017, "end" : 1134, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-42, "score" : 146.6, "model-ac" : "2rovA00" }, { "signature" : { "accession" : "SSF57889", "name" : "Cysteine-rich domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 935, "end" : 999, "hmmLength" : 84, "location-fragments" : [ { "start" : 935, "end" : 999, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.84E-17, "model-ac" : "0043160" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1586, "end" : 1622, "location-fragments" : [ { "start" : 1586, "end" : 1622, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.200.20", "name" : "Phosphorylase Kinase; domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 382, "hmmStart" : 3, "hmmEnd" : 363, "hmmLength" : 213, "hmmBounds" : "INCOMPLETE", "evalue" : 8.6E-187, "score" : 622.2, "envelopeStart" : 16, "envelopeEnd" : 382, "postProcessed" : true, "location-fragments" : [ { "start" : 18, "end" : 170, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 375, "end" : 382, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 2.9E-187, "score" : 623.8, "model-ac" : "3tkuA01" }, { "signature" : { "accession" : "cd00029", "name" : "C1", "description" : "C1", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 946, "end" : 995, "sites" : [ { "description" : "putative DAG/PE binding site", "numLocations" : 10, "siteLocations" : [ { "start" : 967, "end" : 967, "residue" : "I" }, { "start" : 953, "end" : 953, "residue" : "F" }, { "start" : 971, "end" : 971, "residue" : "R" }, { "start" : 966, "end" : 966, "residue" : "M" }, { "start" : 972, "end" : 972, "residue" : "Q" }, { "start" : 968, "end" : 968, "residue" : "G" }, { "start" : 956, "end" : 956, "residue" : "P" }, { "start" : 970, "end" : 970, "residue" : "T" }, { "start" : 957, "end" : 957, "residue" : "T" }, { "start" : 969, "end" : 969, "residue" : "L" } ] }, { "description" : "putative RAS interaction site", "numLocations" : 2, "siteLocations" : [ { "start" : 958, "end" : 958, "residue" : "K" }, { "start" : 956, "end" : 956, "residue" : "P" } ] }, { "description" : "zinc binding sites", "numLocations" : 8, "siteLocations" : [ { "start" : 979, "end" : 979, "residue" : "C" }, { "start" : 987, "end" : 987, "residue" : "C" }, { "start" : 995, "end" : 995, "residue" : "C" }, { "start" : 946, "end" : 946, "residue" : "H" }, { "start" : 959, "end" : 959, "residue" : "C" }, { "start" : 962, "end" : 962, "residue" : "C" }, { "start" : 984, "end" : 984, "residue" : "H" }, { "start" : 976, "end" : 976, "residue" : "C" } ] } ], "evalue" : 2.39285E-16, "score" : 72.5247, "location-fragments" : [ { "start" : 946, "end" : 995, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00029" }, { "signature" : { "accession" : "PS50011", "name" : "PROTEIN_KINASE_DOM", "description" : "Protein kinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 85, "end" : 352, "score" : 44.202, "alignment" : "FEMVKVIGRGAFGEVFVVRMKGSEKVFAMKILNKWEMLRRaEIACFQEERDVLVYGDRRWITNLHYAFQDEANLYLVMDYYCGGDLLTLLSKFEDRLPEDMARFYIAEMVLAISSVHDLRYVHRDIKPDNVLLDANGHIRLADFGSCLKLSEDGTvQSNVAVGTPDYISPEILRamedGQGRYGPECDWWSLGVCMYEMLYGETPF--YaESLVETYGKIMNH----------KncfdfpsdlpveVTNDAKDLMKRLIC-SAEYRLGQNGVEDfknHAWF", "location-fragments" : [ { "start" : 85, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50011" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1534, "end" : 1562, "location-fragments" : [ { "start" : 1534, "end" : 1562, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00069", "name" : "Pkinase", "description" : "Protein kinase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 86, "end" : 352, "hmmStart" : 2, "hmmEnd" : 264, "hmmLength" : 264, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.0E-52, "score" : 177.6, "envelopeStart" : 85, "envelopeEnd" : 352, "postProcessed" : true, "location-fragments" : [ { "start" : 86, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.8E-53, "score" : 179.2, "model-ac" : "PF00069" } ], "xref" : [ { "name" : "XP_018910554.1 PREDICTED: serine/threonine-protein kinase Genghis Khan isoform X3 [Bemisia tabaci]", "id" : "XP_018910554.1" } ] },{ "sequence" : "MSQYYPYKCTPTIYPANPFDANADAEVLRKAMKGFGTDEAAIIEVLGRRGIVQRLEIAEAFKTLYGKDLIDDLKSELSGKFERVILALLTPLPLYYAKELHDAIAGLGTDEGAIIEILCTLSNYGIKTIASFYEKEYEKSLEKDLKGDTSGHFQRLLVSLVQANRDESVDVDQAQVLKDAEDLHAAGVEKSWGTDESVFNSVLATRSYNHLREVFNQYAVIAGHDIEEAISSEFSGSVGKGLLAIAKVVRSKVTYFAERLHDSMAGAGTDDRTLIRIIVSRSEIDLGDIKAAFEEKYGQTLESWIADDTSGDYKKILLKVVQS", "md5" : "dea7b0bf9fafa8a84c1be2bb40155216", "matches" : [ { "signature" : { "accession" : "G3DSA:1.10.220.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 253, "end" : 322, "hmmStart" : 3, "hmmEnd" : 70, "hmmLength" : 73, "hmmBounds" : "COMPLETE", "evalue" : 7.5E-28, "score" : 98.2, "envelopeStart" : 253, "envelopeEnd" : 322, "postProcessed" : true, "location-fragments" : [ { "start" : 253, "end" : 322, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-89, "score" : 294.0, "model-ac" : "1n00A03" }, { "signature" : { "accession" : "PF00191", "name" : "Annexin", "description" : "Annexin", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018502", "name" : "Annexin_repeat", "description" : "Annexin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 24, "end" : 88, "hmmStart" : 2, "hmmEnd" : 66, "hmmLength" : 66, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.3E-24, "score" : 84.4, "envelopeStart" : 23, "envelopeEnd" : 88, "postProcessed" : true, "location-fragments" : [ { "start" : 24, "end" : 88, "dc-status" : "CONTINUOUS" } ] }, { "start" : 255, "end" : 319, "hmmStart" : 1, "hmmEnd" : 65, "hmmLength" : 66, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.1E-22, "score" : 79.9, "envelopeStart" : 255, "envelopeEnd" : 320, "postProcessed" : true, "location-fragments" : [ { "start" : 255, "end" : 319, "dc-status" : "CONTINUOUS" } ] }, { "start" : 179, "end" : 245, "hmmStart" : 2, "hmmEnd" : 66, "hmmLength" : 66, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.1E-19, "score" : 67.6, "envelopeStart" : 178, "envelopeEnd" : 245, "postProcessed" : true, "location-fragments" : [ { "start" : 179, "end" : 245, "dc-status" : "CONTINUOUS" } ] }, { "start" : 95, "end" : 160, "hmmStart" : 1, "hmmEnd" : 66, "hmmLength" : 66, "hmmBounds" : "COMPLETE", "evalue" : 7.1E-23, "score" : 80.5, "envelopeStart" : 95, "envelopeEnd" : 160, "postProcessed" : true, "location-fragments" : [ { "start" : 95, "end" : 160, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-94, "score" : 310.6, "model-ac" : "PF00191" }, { "signature" : { "accession" : "PS00223", "name" : "ANNEXIN_1", "description" : "Annexin repeat signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018252", "name" : "Annexin_repeat_CS", "description" : "Annexin repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 268, "end" : 320, "level" : "STRONG", "cigarAlignment" : "2M8I1M2I1M3I1M2I1M4I1M7I1M3I1M5I1M5I1M2I1M", "alignment" : "GTddrtliriIvsRseiDlgDikaaFeekygqtLeswIaddtsGdykkiLlkV", "location-fragments" : [ { "start" : 268, "end" : 320, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00223" }, { "signature" : { "accession" : "PS51897", "name" : "ANNEXIN_2", "description" : "Annexin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 251, "end" : 322, "score" : 28.046, "alignment" : "SKVTYFAERLHDSMAGAGTDDRTLIRIIVSRSEIDLGDIKAAFEEKYGQTLESWIADDTSGDYKKILLKVVQ", "location-fragments" : [ { "start" : 251, "end" : 322, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51897" }, { "signature" : { "accession" : "G3DSA:1.10.220.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 93, "end" : 164, "hmmStart" : 5, "hmmEnd" : 73, "hmmLength" : 74, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-26, "score" : 94.5, "envelopeStart" : 93, "envelopeEnd" : 164, "postProcessed" : true, "location-fragments" : [ { "start" : 93, "end" : 164, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-96, "score" : 318.5, "model-ac" : "1w3wA02" }, { "signature" : { "accession" : "SSF47874", "name" : "Annexin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3, "end" : 319, "hmmLength" : 343, "location-fragments" : [ { "start" : 3, "end" : 319, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.59E-118, "model-ac" : "0038635" }, { "signature" : { "accession" : "PTHR10502", "name" : "ANNEXIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 321, "hmmStart" : 4, "hmmEnd" : 322, "hmmLength" : 324, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 323, "location-fragments" : [ { "start" : 2, "end" : 321, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.2E-159, "familyName" : "ANNEXIN B9", "score" : 530.3, "model-ac" : "PTHR10502" }, { "signature" : { "accession" : "PR00196", "name" : "ANNEXIN", "description" : "Annexin family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001464", "name" : "Annexin", "description" : "Annexin", "type" : "FAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 73, "end" : 89, "pvalue" : 4.99E-11, "score" : 64.27, "motifNumber" : 2, "location-fragments" : [ { "start" : 73, "end" : 89, "dc-status" : "CONTINUOUS" } ] }, { "start" : 100, "end" : 121, "pvalue" : 1.81E-10, "score" : 52.53, "motifNumber" : 3, "location-fragments" : [ { "start" : 100, "end" : 121, "dc-status" : "CONTINUOUS" } ] }, { "start" : 33, "end" : 55, "pvalue" : 8.94E-10, "score" : 51.05, "motifNumber" : 1, "location-fragments" : [ { "start" : 33, "end" : 55, "dc-status" : "CONTINUOUS" } ] }, { "start" : 308, "end" : 321, "pvalue" : 2.51E-7, "score" : 59.92, "motifNumber" : 7, "location-fragments" : [ { "start" : 308, "end" : 321, "dc-status" : "CONTINUOUS" } ] }, { "start" : 184, "end" : 210, "pvalue" : 7.41E-10, "score" : 42.11, "motifNumber" : 4, "location-fragments" : [ { "start" : 184, "end" : 210, "dc-status" : "CONTINUOUS" } ] }, { "start" : 264, "end" : 284, "pvalue" : 7.42E-14, "score" : 72.66, "motifNumber" : 5, "location-fragments" : [ { "start" : 264, "end" : 284, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.6E-53, "graphscan" : "IIIII.I", "model-ac" : "PR00196" }, { "signature" : { "accession" : "PS51897", "name" : "ANNEXIN_2", "description" : "Annexin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 91, "end" : 162, "score" : 27.54, "alignment" : "PLPLYYAKELHDAIAGLGTDEGAIIEILCTLSNYGIKTIASFYEKEYEKSLEKDLKGDTSGHFQRLLVSLVQ", "location-fragments" : [ { "start" : 91, "end" : 162, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51897" }, { "signature" : { "accession" : "PTHR10502:SF184", "name" : "ANNEXIN B9", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 321, "hmmStart" : 4, "hmmEnd" : 322, "hmmLength" : 324, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 323, "location-fragments" : [ { "start" : 2, "end" : 321, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.2E-159, "familyName" : "ANNEXIN B9", "score" : 530.3, "model-ac" : "PTHR10502:SF184" }, { "signature" : { "accession" : "G3DSA:1.10.220.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 18, "end" : 90, "hmmStart" : 2, "hmmEnd" : 72, "hmmLength" : 73, "hmmBounds" : "COMPLETE", "evalue" : 7.5E-29, "score" : 101.6, "envelopeStart" : 18, "envelopeEnd" : 90, "postProcessed" : true, "location-fragments" : [ { "start" : 18, "end" : 90, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-91, "score" : 302.6, "model-ac" : "1hm6A01" }, { "signature" : { "accession" : "PS51897", "name" : "ANNEXIN_2", "description" : "Annexin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 174, "end" : 247, "score" : 23.76, "alignment" : "AQVLKDAEDLHAAGVEksWGTDESVFNSVLATRSYNHLREVFNQYAVIAGHDIEEAISSEFSGSVGKGLLAIAK", "location-fragments" : [ { "start" : 174, "end" : 247, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51897" }, { "signature" : { "accession" : "G3DSA:1.10.220.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 165, "end" : 251, "hmmStart" : 1, "hmmEnd" : 84, "hmmLength" : 86, "hmmBounds" : "COMPLETE", "evalue" : 3.2E-26, "score" : 93.3, "envelopeStart" : 165, "envelopeEnd" : 251, "postProcessed" : true, "location-fragments" : [ { "start" : 165, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-94, "score" : 312.3, "model-ac" : "1hm6A03" }, { "signature" : { "accession" : "SM00335", "name" : "annex3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR018502", "name" : "Annexin_repeat", "description" : "Annexin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 268, "end" : 320, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 6.5E-22, "score" : 88.8, "location-fragments" : [ { "start" : 268, "end" : 320, "dc-status" : "CONTINUOUS" } ] }, { "start" : 193, "end" : 245, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 3.5E-15, "score" : 66.4, "location-fragments" : [ { "start" : 193, "end" : 245, "dc-status" : "CONTINUOUS" } ] }, { "start" : 36, "end" : 88, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 4.1E-24, "score" : 96.1, "location-fragments" : [ { "start" : 36, "end" : 88, "dc-status" : "CONTINUOUS" } ] }, { "start" : 108, "end" : 160, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-22, "score" : 90.8, "location-fragments" : [ { "start" : 108, "end" : 160, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-98, "score" : 342.2, "model-ac" : "SM00335" }, { "signature" : { "accession" : "PS51897", "name" : "ANNEXIN_2", "description" : "Annexin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 90, "score" : 30.169, "alignment" : "FDANADAEVLRKAMKGFGTDEAAIIEVLGRRGIVQRLEIAEAFKTLYGKDLIDDLKSELSGKFERVILALLT", "location-fragments" : [ { "start" : 19, "end" : 90, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51897" }, { "signature" : { "accession" : "PS00223", "name" : "ANNEXIN_1", "description" : "Annexin repeat signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018252", "name" : "Annexin_repeat_CS", "description" : "Annexin repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 36, "end" : 88, "level" : "STRONG", "cigarAlignment" : "2M8I1M2I1M3I1M2I1M4I1M7I1M3I1M5I1M5I1M2I1M", "alignment" : "GTdeaaiievLgrRgivQrlEiaeaFktlygkdLiddLkselsGkfervIlaL", "location-fragments" : [ { "start" : 36, "end" : 88, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00223" } ], "xref" : [ { "name" : "XP_018909640.1 PREDICTED: annexin B9 isoform X3 [Bemisia tabaci]", "id" : "XP_018909640.1" } ] },{ "sequence" : "MSIHTSGLPTFLSTLFPLGNVPPVCLTQDLPPEADAHILLLGCGDARNILFTCFADNQRKLDVTCCDIAPMIHARNVLLYTLISDDESNENIELIWNLYYHWKIDGNSVDLLESQIQRLLAVSESIDHWHNSVYGSMIRFCDEKSLSCVRAYWEGFTTRGLSNSAKKDRLKRLQAAIDRVREDRLLNGGPDYKGYRALFPTNMNVDGQAWSALDSVAKQWWGYGMVSAENTRAVQPAHLNPVFLYSPDGELTMHEGTSPLGSLPLCTAYILLSKESPLYQEKKGRSPTQHLVNCAKSNFFQWAPAFRKAIKNGSVIRIFSGHAFPFCFTLRNCQLTGSTSMNLPFHNWTNSPLILHHSDYGDSKDSAPLSFDVIDTSNLADYLGPLNVVALTSSLLKRNVSSCLYTQLMVMFDSSLQERLTNLFGVDVRSMSFLLGLVLPDLFTNATSTVDEYPNIDKIIVQKPGSICRPTVVSRLRWRRLGTPGMLPSVQVEAKELAKFLTHVHRAMFQLDDLPDIFGHHNLTREDALKDLHRPYNRASFAFLLSHLKATLTVDWDECLKEIYNVLGVDGQKGLSNNYHLEDLLLNLHAFGVDSSHFTKPNPANMNGTILASVLSECGDLPDQLCVTIRVPKKHLNAIGKCLGSQGIVCHFEGRNPQGQVYRRSFSSVQMAFRKLDESNGEVHSNPLSFEGSGVFFCTSDVFASVMVPTSMLISMLLQSVPKVKFIVKYNPMTYMFYFMKLGPELCFFSTEITSSDVSITKFMPGMSGLPRFINLENREVKLASNSTSVRFSGDGLKINSLIRRITLESETDKAVLANKSSVVQVKFLSPYVAVANIGRSLEFKFEFPAPVSISKHKVRIARKSSYIEIESRFLDPVEEDVPVFLFPCFLSQTPPNIVSWSSMRVNLDVMPSIDLDNGQELTWLNDYLGQMFSREEYQNFLSRTDDLRVSIKESIMQFFMGFAGLYLRRDNFVCLEGMDQSRKALILPSCLRLDLASYSVVLDSALIPLTNTVMSDKVVTRFLKKLYDNDVVRKVPVNDSVNRAWKAMMPAMVERCRTWNHTSGCDYKKIGEVPLPQGLDRDGESSICTCGVGKFPKGYLKDLIKEFSAVNHLLRQYATRVAISPFFAVTYVDNCDLTDFINVVCSKCGDEKRKNPTAKQQSLLKCSRCKTVQYCSVDCQKADWKQHKVFCKAMQDCVP", "md5" : "376a4b3b10032fc00849d92d020965a6", "matches" : [ { "signature" : { "accession" : "PS01360", "name" : "ZF_MYND_1", "description" : "Zinc finger MYND-type signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR002893", "name" : "Znf_MYND", "description" : "Zinc finger, MYND-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1146, "end" : 1192, "level" : "STRONG", "cigarAlignment" : "1M2I1M17I1M2I1M4I2M3I1M7I1M3I1M", "alignment" : "CskCgdekrknptakqqsllkCsrCktvqYCsvdCqkadwkqHkvfC", "location-fragments" : [ { "start" : 1146, "end" : 1192, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01360" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 163, "end" : 183, "location-fragments" : [ { "start" : 163, "end" : 183, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PS50865", "name" : "ZF_MYND_2", "description" : "Zinc finger MYND-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002893", "name" : "Znf_MYND", "description" : "Zinc finger, MYND-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1146, "end" : 1192, "score" : 12.251, "alignment" : "CSKCGDEKRKnptakqqslLKCSRCKTVQYCSVDCQKADWKQHKVFC", "location-fragments" : [ { "start" : 1146, "end" : 1192, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50865" }, { "signature" : { "accession" : "PF01753", "name" : "zf-MYND", "description" : "MYND finger", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002893", "name" : "Znf_MYND", "description" : "Zinc finger, MYND-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1146, "end" : 1192, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 3.4E-10, "score" : 39.8, "envelopeStart" : 1146, "envelopeEnd" : 1192, "postProcessed" : true, "location-fragments" : [ { "start" : 1146, "end" : 1192, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-10, "score" : 41.0, "model-ac" : "PF01753" }, { "signature" : { "accession" : "G3DSA:3.30.60.180", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1142, "end" : 1194, "hmmStart" : 11, "hmmEnd" : 49, "hmmLength" : 52, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-13, "score" : 51.4, "envelopeStart" : 1142, "envelopeEnd" : 1194, "postProcessed" : true, "location-fragments" : [ { "start" : 1142, "end" : 1194, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-13, "score" : 52.7, "model-ac" : "2jw6A00" }, { "signature" : { "accession" : "SSF144232", "name" : "HIT/MYND zinc finger-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 1143, "end" : 1197, "hmmLength" : 57, "location-fragments" : [ { "start" : 1143, "end" : 1197, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.52E-11, "model-ac" : "0052402" }, { "signature" : { "accession" : "PF14737", "name" : "DUF4470", "description" : "Domain of unknown function (DUF4470)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR027974", "name" : "DUF4470", "description" : "Domain of unknown function DUF4470", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 17, "end" : 103, "hmmStart" : 1, "hmmEnd" : 100, "hmmLength" : 101, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.0E-22, "score" : 80.2, "envelopeStart" : 17, "envelopeEnd" : 104, "postProcessed" : true, "location-fragments" : [ { "start" : 17, "end" : 103, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-23, "score" : 81.1, "model-ac" : "PF14737" } ], "xref" : [ { "name" : "XP_018910431.1 PREDICTED: uncharacterized protein LOC109039419 [Bemisia tabaci]", "id" : "XP_018910431.1" } ] },{ "sequence" : "MDLKGKVALVTGGASGIGRAFAEELVKYGAKVSICDVNDDGEELADQLCQKYGRDRAIFCSCDVTDYPQIEESFQTTVSAYGGIDIVINNAGIFNDRFWELEVDVNLNGVIRGTLLALRYMSKHRGGRGGTIINVAAVEGYSVFPAAPIYCATKHAVVGFTRSYGSPFHTNMTGVRFIALCPGGTKTGMIPENDWKKTLQAPEYEAALPKTINQQQLVQNVGRALIYVLQKAPTGSVWSVENNQLPTEIKLPFN", "md5" : "449905543b57e5f8a3e7b83633545e69", "matches" : [ { "signature" : { "accession" : "PTHR44229:SF4", "name" : "15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 245, "hmmStart" : 1, "hmmEnd" : 249, "hmmLength" : 275, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 253, "location-fragments" : [ { "start" : 1, "end" : 245, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-87, "familyName" : "15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]", "score" : 296.1, "model-ac" : "PTHR44229:SF4" }, { "signature" : { "accession" : "PR00081", "name" : "GDHRDH", "description" : "Glucose/ribitol dehydrogenase family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002347", "name" : "SDR_fam", "description" : "Short-chain dehydrogenase/reductase SDR", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 150, "end" : 169, "pvalue" : 3.57E-6, "score" : 31.83, "motifNumber" : 4, "location-fragments" : [ { "start" : 150, "end" : 169, "dc-status" : "CONTINUOUS" } ] }, { "start" : 7, "end" : 24, "pvalue" : 3.39E-11, "score" : 55.19, "motifNumber" : 1, "location-fragments" : [ { "start" : 7, "end" : 24, "dc-status" : "CONTINUOUS" } ] }, { "start" : 124, "end" : 140, "pvalue" : 2.76E-5, "score" : 28.96, "motifNumber" : 3, "location-fragments" : [ { "start" : 124, "end" : 140, "dc-status" : "CONTINUOUS" } ] }, { "start" : 173, "end" : 190, "pvalue" : 4.57E-5, "score" : 31.11, "motifNumber" : 5, "location-fragments" : [ { "start" : 173, "end" : 190, "dc-status" : "CONTINUOUS" } ] }, { "start" : 82, "end" : 93, "pvalue" : 7.88E-8, "score" : 57.91, "motifNumber" : 2, "location-fragments" : [ { "start" : 82, "end" : 93, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-26, "graphscan" : "IIiII.", "model-ac" : "PR00081" }, { "signature" : { "accession" : "G3DSA:3.40.50.720", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 250, "hmmStart" : 12, "hmmEnd" : 253, "hmmLength" : 271, "hmmBounds" : "COMPLETE", "evalue" : 7.8E-66, "score" : 224.1, "envelopeStart" : 1, "envelopeEnd" : 250, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 250, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-66, "score" : 224.3, "model-ac" : "5ilgB00" }, { "signature" : { "accession" : "PTHR44229", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 245, "hmmStart" : 1, "hmmEnd" : 249, "hmmLength" : 275, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 253, "location-fragments" : [ { "start" : 1, "end" : 245, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-87, "familyName" : "15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]", "score" : 296.1, "model-ac" : "PTHR44229" }, { "signature" : { "accession" : "PR00080", "name" : "SDRFAMILY", "description" : "Short-chain dehydrogenase/reductase (SDR) superfamily signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002347", "name" : "SDR_fam", "description" : "Short-chain dehydrogenase/reductase SDR", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 150, "end" : 169, "pvalue" : 8.39E-7, "score" : 34.32, "motifNumber" : 3, "location-fragments" : [ { "start" : 150, "end" : 169, "dc-status" : "CONTINUOUS" } ] }, { "start" : 82, "end" : 93, "pvalue" : 1.05E-7, "score" : 55.73, "motifNumber" : 1, "location-fragments" : [ { "start" : 82, "end" : 93, "dc-status" : "CONTINUOUS" } ] }, { "start" : 130, "end" : 138, "pvalue" : 1.14E-4, "score" : 45.79, "motifNumber" : 2, "location-fragments" : [ { "start" : 130, "end" : 138, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-11, "graphscan" : "III", "model-ac" : "PR00080" }, { "signature" : { "accession" : "SSF51735", "name" : "NAD(P)-binding Rossmann-fold domains", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036291", "name" : "NAD(P)-bd_dom_sf", "description" : "NAD(P)-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 244, "hmmLength" : 254, "location-fragments" : [ { "start" : 1, "end" : 244, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.33E-55, "model-ac" : "0035305" }, { "signature" : { "accession" : "PF00106", "name" : "adh_short", "description" : "short chain dehydrogenase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002347", "name" : "SDR_fam", "description" : "Short-chain dehydrogenase/reductase SDR", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 191, "hmmStart" : 1, "hmmEnd" : 188, "hmmLength" : 195, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.0E-47, "score" : 162.1, "envelopeStart" : 6, "envelopeEnd" : 197, "postProcessed" : true, "location-fragments" : [ { "start" : 6, "end" : 191, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.8E-48, "score" : 162.5, "model-ac" : "PF00106" }, { "signature" : { "accession" : "PS00061", "name" : "ADH_SHORT", "description" : "Short-chain dehydrogenases/reductases family signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR020904", "name" : "Sc_DH/Rdtase_CS", "description" : "Short-chain dehydrogenase/reductase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 137, "end" : 165, "level" : "STRONG", "cigarAlignment" : "1M9I1M2I8M1I3M1I3M", "alignment" : "AvegysvfpaApiYCATKHAVvGFTrSYG", "location-fragments" : [ { "start" : 137, "end" : 165, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00061" } ], "xref" : [ { "name" : "XP_018909709.1 PREDICTED: 15-hydroxyprostaglandin dehydrogenase [NAD(+)]-like [Bemisia tabaci]", "id" : "XP_018909709.1" } ] },{ "sequence" : "MVRSHFPGKPRSGHRKLISASSCAGGSNEASLVAENIYHGLSAFNATFGHENEQLSTFHGFSPHQVSDAKKAAEASYKHVEKECEARGVIFNPFLPSNKFLKRYQTATGCGAEINCNMCPLEDKENTEKLNCDTDCSDIMSNGPMTSNRMSNSRSNKKILRENLESPDISMDSFSSDSDMCSSKGKLNNANSRKFVLPCRSIHSSRVIKPNKRFMDSAIDDSETASVSSETGENQPLQSSNFVPLKKPKLIFDENKGRDVCWKIDASDATNSSLTSTPSTSRSPLSKGILREAILNIELSPIKTEGLKSSNRAKANTIVCGVCGAVRFYKFKKQTRKFGVISCESCRKFISKMVNLLPTKNAASYNGGVLECHNQKGRIGCCDNPSILRNKEWNFKNVKLVNNQRCPACWLNTCIRKYNIPIDKRIGLSKMVPQEMRIPEFCEEATLSSHEIDYSQQQSDSGVTRWRRTHDKLSKLRKKRHKNAINSISNMARFISAVKNRDQSNETRQKKMEIESRMRVAKNLRKRTSTSLRSKCTDTTVQKLKKNTKDLSKKNKIKKLKKLIRRNIEKRVDNRGVNKASIEERRDKYFMKGPRVKHVCRSASIVLGQPMATFPISSTTVSNNNSPKSKEKENPQSSETPRAETPEPRIKESTPVSAISTSDPNDSDEIFEAPTIKIRDVSQKSTDSAERPFEEIPLARTLQDLGKQQEEEAENQTISVDFWENYDPEEVCKTGFALIASEPIHVPALCFLCGSAGVDRLVHCVSCCEAYHQYCVEMNMHPSKLSLDRNWWRVDWICPKCTFCTVCNDPAPQLCCQRCLKSYHSNCLSPNRQRPHLTDKTWVCPSCLRCKSCNQTNVSKFIGNLPLCSPCFKLRQKGNFCPLCQRCYEDDDYDSKMMECGKCKSWVHAKCEGLSNEKYQVLSYLPESVEYICRVCCDIPPASWWLAVEEELKTGYLNVLKCLSKNKKACDILKWSPKKRTADCVCRSNVRVKPLRFSDSQPSGSKTIHDSDNKCLSKDSLCDIKQNELASNLSDSDMNESDINLNKTSGSSTLNASNLLHVSVENNDCQGNFYGTNSDKTEQFSPHATQSDSGIGSTDDELKATSSIDGESNLDERSFSSGQCYCSGLETWTKAAPTLLSIKKKVSGNEYSSLLQFHDDVESVINSIVESEDLTQVYHQTMAEVFPWFDPQESKVFDASCATSSCDVSMDDNLELETNDIADDLKNEMDENITCLLGYEKDYYYLGKEEKDERICALCKGVSEGPMFEEGRLLYCGHNDWIHSNCALWSSEVFEEIDGSLQNVHSAISRGKMIRCSKCAKKGATVGCCTRNCTETYHFPCAREASCTFLESKTIRCQTHAAGNFEDKILTRQEEFHISRPVYVELERKKKRFLDYRAVKLVVGSLHIHSLGKFEPQVSDTSFAIIPIEFSCSRLFWSSSEPWKVIPYHIKTILIDANCEYDADLDMNYTVDHSVVNESIEEINLAVCEVVSFLCDSVQFKEEESEGQSNVSDLLSEQDTIFEDLPNEFFDGVFKDISMKMMSIEDLVAAGDKDDSNPSDSDGNNMMEIGEDDSQNCPADLPLKRNFDFSLSSRFPKIDSITQTESAESICSSKNVFCKGLSLEKGEDAVLHVKIQEEYNETNDNSAYYLKESNLNSLRLLQVDGVVDCSSCSDTSSNSDESESFWPEEENQMTKKNYIEEARLQNESPTYEIPQLDGSIEISDETEENPVKCSRCRRTYRTDVSYQRHLSSCNAEYMSSSGESDNEDETKCNSIHNRSTETSNSDIGDSLHVSEINLVDDVTVTMQNSSSINMVSDNKNLGNNFEFTSSGNSAISIDQTESLPSIDSKKVNPTNTFCASITVSKAAFLSGVTSSGGPQYVNSINGKGRPLKTSFMVGKSEPLPPPAQFGNPIMYQQTPTIMDQPQYTGASVTTPTFILQQVPQQMASASINISSFVQPVNSTPNVQYIAAVESSNQPQFIATPDPMNPGSFRIQQSSLISPIVPQVVGAIIQPPVEQIVTMNPQASNIDFFAAPNPSNNIFLSSQPVMNAVVNNSILCNSVMSNSLLNNTLVNNPVMSNAVLNNSLISNPLVSNGYHTMTSQLVQSSKPAIEATSYVIVTTNPSVKDCFSAPLSVQSAQSTTWAPSSNWSFNKHTCKTTKEVTTLYHAKGELIPNQCKPSQVNCVKVVKKETTEEMMIETASVNNPFYEKISAELPTDENVPADEVSRLTNFVKDIPAIFNAHSLKPLTPLPNSSNSSILHQQNESSKDVVLELGTKVPSISISKTTCAPSPSHLCTLTAPQTEFRISTSISKPQVAVCKSVDENVETLDPPSSPPYSVTEVFSNQIKNFRTYSGKKLASKLPINNVLQRTDEKQRTNNILQAVSSTVTSTSSSPQYVKNDISYSNSIIQTSPLSSVNNIINSVLSSKAPLSCKISSKEQVNSPPKTFHSDYLADSRILKPANKIENLESKIKNGLTKHENALTKPKTNLKNGKKCNKPKVVFEINSEDGFSYSTTNLADAWQKIFEAVQQAREARKLPPLPQNPFKNAEASLRTLGLDNNGLKYLLEQLPGVGRCAKYKPTYHKPKPNIARQDSLKENKSGCARSEPLSTRKEKYDMFSWLASRHRRPPKLLIASEADLINGNRRSTSINLPMAMRFRHLRETSREAVGVFRSDIHGRGLFCLRDIDAGEMVIEYAGEVIRSALTDKRENFYNSKGIGCYMFRIDDYYVVDATLKGNAARFINHSCEPNCYSRIVDILGKKHILIFAQRRIPQGEELTYDYKFPLEDDKISCHCLSRKCRKYLN", "md5" : "ba9f68753d303d81dd3dba655d509317", "matches" : [ { "signature" : { "accession" : "PF05964", "name" : "FYRN", "description" : "F/Y-rich N-terminus", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR003888", "name" : "FYrich_N", "description" : "FY-rich, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" } ], "pathwayXRefs" : [ { "name" : "PKMTs methylate histone lysines", "databaseName" : "Reactome", "id" : "R-HSA-3214841" }, { "name" : "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function", "databaseName" : "Reactome", "id" : "R-HSA-8936459" } ] } }, "locations" : [ { "start" : 1404, "end" : 1451, "hmmStart" : 1, "hmmEnd" : 50, "hmmLength" : 51, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.6E-9, "score" : 35.4, "envelopeStart" : 1404, "envelopeEnd" : 1452, "postProcessed" : true, "location-fragments" : [ { "start" : 1404, "end" : 1451, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-9, "score" : 37.0, "model-ac" : "PF05964" }, { "signature" : { "accession" : "PS50016", "name" : "ZF_PHD_2", "description" : "Zinc finger PHD-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR019787", "name" : "Znf_PHD-finger", "description" : "Zinc finger, PHD-finger", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 878, "end" : 939, "score" : 9.419, "alignment" : "GNFCPLCQRCYEDddyDSKMMECGKCKSWVHAKCEGLSNEkyqvlSYLPESVEYICRVCCDI", "location-fragments" : [ { "start" : 878, "end" : 939, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50016" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 617, "end" : 631, "location-fragments" : [ { "start" : 617, "end" : 631, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 213, "end" : 240, "location-fragments" : [ { "start" : 213, "end" : 240, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 654, "end" : 668, "location-fragments" : [ { "start" : 654, "end" : 668, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00184", "name" : "ring_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1256, "end" : 1319, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.35, "score" : 15.2, "location-fragments" : [ { "start" : 1256, "end" : 1319, "dc-status" : "CONTINUOUS" } ] }, { "start" : 750, "end" : 801, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 4.4, "score" : 5.7, "location-fragments" : [ { "start" : 750, "end" : 801, "dc-status" : "CONTINUOUS" } ] }, { "start" : 804, "end" : 847, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.35, "score" : 15.2, "location-fragments" : [ { "start" : 804, "end" : 847, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-6, "score" : 36.1, "model-ac" : "SM00184" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1760, "end" : 1783, "location-fragments" : [ { "start" : 1760, "end" : 1783, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 221, "end" : 240, "location-fragments" : [ { "start" : 221, "end" : 240, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF13771", "name" : "zf-HC5HC2H", "description" : "PHD-like zinc-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 1283, "end" : 1360, "hmmStart" : 1, "hmmEnd" : 89, "hmmLength" : 90, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.0E-9, "score" : 37.6, "envelopeStart" : 1283, "envelopeEnd" : 1361, "postProcessed" : true, "location-fragments" : [ { "start" : 1283, "end" : 1360, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-9, "score" : 37.6, "model-ac" : "PF13771" }, { "signature" : { "accession" : "PS51805", "name" : "EPHD", "description" : "Extended PHD (ePHD) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR034732", "name" : "EPHD", "description" : "Extended PHD (ePHD) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1253, "end" : 1361, "score" : 27.72, "alignment" : "ERICALCKGVSEgpmFEEGRLLYCGHnDWIHSNCALWSSEVFEEIDGS---LQNVHSAISRGKMIRCSKCAKKGATVGCCTRNCTETYHFPCAREASCtFL------ESKTIRCQTHA", "location-fragments" : [ { "start" : 1253, "end" : 1361, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51805" }, { "signature" : { "accession" : "PTHR45838", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1705, "end" : 2806, "hmmStart" : 1799, "hmmEnd" : 2450, "hmmLength" : 2450, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 1637, "envelopeEnd" : 2806, "location-fragments" : [ { "start" : 1705, "end" : 2806, "dc-status" : "CONTINUOUS" } ] }, { "start" : 86, "end" : 615, "hmmStart" : 294, "hmmEnd" : 677, "hmmLength" : 2450, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 45, "envelopeEnd" : 618, "location-fragments" : [ { "start" : 86, "end" : 615, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-280, "familyName" : "HISTONE-LYSINE N-METHYLTRANSFERASE 2B", "score" : 935.7, "model-ac" : "PTHR45838" }, { "signature" : { "accession" : "PS51030", "name" : "NUCLEAR_REC_DBD_2", "description" : "Nuclear hormone receptors DNA-binding domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001628", "name" : "Znf_hrmn_rcpt", "description" : "Zinc finger, nuclear hormone receptor-type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "sequence-specific DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0043565" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" }, { "name" : "regulation of transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006355" }, { "name" : "DNA-binding transcription factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003700" } ], "pathwayXRefs" : [ { "name" : "Nuclear Receptor transcription pathway", "databaseName" : "Reactome", "id" : "R-HSA-383280" } ] } }, "locations" : [ { "start" : 317, "end" : 435, "score" : 8.875, "alignment" : "TIVCGVCGAvrfykfKKQTRKFGVISCESCRKFISKMVNLLPtknaasynggVLECHNQKGrigcCDNpsilrnkewnfknvKLVNNQRCPACWLNTCIRkynipidkrIGLSKMVPQE", "location-fragments" : [ { "start" : 317, "end" : 435, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51030" }, { "signature" : { "accession" : "PS51543", "name" : "FYRC", "description" : "FYR domain FYRC motif profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR003889", "name" : "FYrich_C", "description" : "FY-rich, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" } ], "pathwayXRefs" : [ { "name" : "PKMTs methylate histone lysines", "databaseName" : "Reactome", "id" : "R-HSA-3214841" }, { "name" : "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function", "databaseName" : "Reactome", "id" : "R-HSA-8936459" } ] } }, "locations" : [ { "start" : 2499, "end" : 2584, "score" : 19.461, "alignment" : "KPKVVFEINSED--GFSYSTTNLADAWQkIFEAVQQAREARklppLPQNPFKNAEASLRTLGLDNNGLKYLLEQLPGVGRCAKYKPTY", "location-fragments" : [ { "start" : 2499, "end" : 2584, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51543" }, { "signature" : { "accession" : "PTHR45838:SF3", "name" : "HISTONE-LYSINE N-METHYLTRANSFERASE 2B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1132, "end" : 1452, "hmmStart" : 1212, "hmmEnd" : 1553, "hmmLength" : 2450, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1117, "envelopeEnd" : 1519, "location-fragments" : [ { "start" : 1132, "end" : 1452, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-280, "familyName" : "HISTONE-LYSINE N-METHYLTRANSFERASE 2B", "score" : 935.7, "model-ac" : "PTHR45838:SF3" }, { "signature" : { "accession" : "SSF57903", "name" : "FYVE/PHD zinc finger", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011011", "name" : "Znf_FYVE_PHD", "description" : "Zinc finger, FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 793, "end" : 853, "hmmLength" : 88, "location-fragments" : [ { "start" : 793, "end" : 853, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.52E-7, "model-ac" : "0050474" }, { "signature" : { "accession" : "G3DSA:3.30.40.10", "name" : "Zinc/RING finger domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013083", "name" : "Znf_RING/FYVE/PHD", "description" : "Zinc finger, RING/FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1250, "end" : 1363, "hmmStart" : 5, "hmmEnd" : 126, "hmmLength" : 129, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-23, "score" : 85.1, "envelopeStart" : 1250, "envelopeEnd" : 1363, "postProcessed" : true, "location-fragments" : [ { "start" : 1250, "end" : 1363, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-23, "score" : 85.1, "model-ac" : "4nn2B00" }, { "signature" : { "accession" : "PTHR45838:SF3", "name" : "HISTONE-LYSINE N-METHYLTRANSFERASE 2B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 86, "end" : 615, "hmmStart" : 294, "hmmEnd" : 677, "hmmLength" : 2450, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 45, "envelopeEnd" : 618, "location-fragments" : [ { "start" : 86, "end" : 615, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-280, "familyName" : "HISTONE-LYSINE N-METHYLTRANSFERASE 2B", "score" : 935.7, "model-ac" : "PTHR45838:SF3" }, { "signature" : { "accession" : "PTHR45838:SF3", "name" : "HISTONE-LYSINE N-METHYLTRANSFERASE 2B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 632, "end" : 974, "hmmStart" : 859, "hmmEnd" : 1197, "hmmLength" : 2450, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 617, "envelopeEnd" : 995, "location-fragments" : [ { "start" : 632, "end" : 974, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-280, "familyName" : "HISTONE-LYSINE N-METHYLTRANSFERASE 2B", "score" : 935.7, "model-ac" : "PTHR45838:SF3" }, { "signature" : { "accession" : "SM00542", "name" : "fyrc_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003889", "name" : "FYrich_C", "description" : "FY-rich, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" } ], "pathwayXRefs" : [ { "name" : "PKMTs methylate histone lysines", "databaseName" : "Reactome", "id" : "R-HSA-3214841" }, { "name" : "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function", "databaseName" : "Reactome", "id" : "R-HSA-8936459" } ] } }, "locations" : [ { "start" : 2503, "end" : 2590, "hmmStart" : 1, "hmmEnd" : 97, "hmmLength" : 97, "hmmBounds" : "COMPLETE", "evalue" : 8.1E-13, "score" : 58.6, "location-fragments" : [ { "start" : 2503, "end" : 2590, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.1E-13, "score" : 58.6, "model-ac" : "SM00542" }, { "signature" : { "accession" : "PS50280", "name" : "SET", "description" : "SET domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001214", "name" : "SET_dom", "description" : "SET domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2668, "end" : 2784, "score" : 20.299, "alignment" : "EAVGVFRSDIHGRGLFCLRDIDAGE--------------------MVIE------YagevirSALTDKREnFYNSKGIgcymfriDDYYVVDATLKGN---AARFINHSCEPNCYSRIVDIlGKkHILIFAQRRIPQGEELTYDYK", "location-fragments" : [ { "start" : 2668, "end" : 2784, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50280" }, { "signature" : { "accession" : "cd15508", "name" : "PHD3_KMT2A_like", "description" : "PHD3_KMT2A_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 880, "end" : 936, "sites" : [ { "description" : "Zn binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 908, "end" : 908, "residue" : "H" }, { "start" : 881, "end" : 881, "residue" : "C" }, { "start" : 884, "end" : 884, "residue" : "C" }, { "start" : 900, "end" : 900, "residue" : "C" }, { "start" : 903, "end" : 903, "residue" : "C" }, { "start" : 911, "end" : 911, "residue" : "C" }, { "start" : 933, "end" : 933, "residue" : "C" }, { "start" : 936, "end" : 936, "residue" : "C" } ] }, { "description" : "putative histone H3 binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 898, "end" : 898, "residue" : "M" }, { "start" : 896, "end" : 896, "residue" : "K" }, { "start" : 900, "end" : 900, "residue" : "C" }, { "start" : 904, "end" : 904, "residue" : "K" }, { "start" : 897, "end" : 897, "residue" : "M" }, { "start" : 931, "end" : 931, "residue" : "Y" }, { "start" : 880, "end" : 880, "residue" : "F" }, { "start" : 899, "end" : 899, "residue" : "E" } ] } ], "evalue" : 8.87914E-32, "score" : 117.161, "location-fragments" : [ { "start" : 880, "end" : 936, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd15508" }, { "signature" : { "accession" : "PTHR45838:SF3", "name" : "HISTONE-LYSINE N-METHYLTRANSFERASE 2B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1705, "end" : 2806, "hmmStart" : 1799, "hmmEnd" : 2450, "hmmLength" : 2450, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 1637, "envelopeEnd" : 2806, "location-fragments" : [ { "start" : 1705, "end" : 2806, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-280, "familyName" : "HISTONE-LYSINE N-METHYLTRANSFERASE 2B", "score" : 935.7, "model-ac" : "PTHR45838:SF3" }, { "signature" : { "accession" : "cd15506", "name" : "PHD1_KMT2A_like", "description" : "PHD1_KMT2A_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 749, "end" : 801, "sites" : [ { "description" : "putative histone H3 binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 760, "end" : 760, "residue" : "R" }, { "start" : 796, "end" : 796, "residue" : "W" }, { "start" : 749, "end" : 749, "residue" : "L" }, { "start" : 764, "end" : 764, "residue" : "C" }, { "start" : 762, "end" : 762, "residue" : "V" }, { "start" : 761, "end" : 761, "residue" : "L" }, { "start" : 763, "end" : 763, "residue" : "H" }, { "start" : 768, "end" : 768, "residue" : "C" } ] }, { "description" : "Zn binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 750, "end" : 750, "residue" : "C" }, { "start" : 798, "end" : 798, "residue" : "C" }, { "start" : 772, "end" : 772, "residue" : "H" }, { "start" : 764, "end" : 764, "residue" : "C" }, { "start" : 753, "end" : 753, "residue" : "C" }, { "start" : 801, "end" : 801, "residue" : "C" }, { "start" : 767, "end" : 767, "residue" : "C" }, { "start" : 775, "end" : 775, "residue" : "C" } ] } ], "evalue" : 1.19985E-13, "score" : 65.0733, "location-fragments" : [ { "start" : 749, "end" : 801, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd15506" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1075, "end" : 1111, "location-fragments" : [ { "start" : 1075, "end" : 1111, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:2.170.270.10", "name" : "SET domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 2576, "end" : 2806, "hmmStart" : 104, "hmmEnd" : 256, "hmmLength" : 278, "hmmBounds" : "COMPLETE", "evalue" : 5.5E-54, "score" : 185.4, "envelopeStart" : 2576, "envelopeEnd" : 2806, "postProcessed" : true, "location-fragments" : [ { "start" : 2576, "end" : 2806, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-54, "score" : 185.4, "model-ac" : "5lszA00" }, { "signature" : { "accession" : "G3DSA:3.30.40.10", "name" : "Zinc/RING finger domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013083", "name" : "Znf_RING/FYVE/PHD", "description" : "Zinc finger, RING/FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 875, "end" : 939, "hmmStart" : 3, "hmmEnd" : 64, "hmmLength" : 67, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-25, "score" : 91.2, "envelopeStart" : 875, "envelopeEnd" : 939, "postProcessed" : true, "location-fragments" : [ { "start" : 875, "end" : 939, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-25, "score" : 91.2, "model-ac" : "2kyuA00" }, { "signature" : { "accession" : "SSF57903", "name" : "FYVE/PHD zinc finger", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011011", "name" : "Znf_FYVE_PHD", "description" : "Zinc finger, FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 747, "end" : 802, "hmmLength" : 91, "location-fragments" : [ { "start" : 747, "end" : 802, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.02E-5, "model-ac" : "0050473" }, { "signature" : { "accession" : "PS51542", "name" : "FYRN", "description" : "FYR domain FYRN motif profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR003888", "name" : "FYrich_N", "description" : "FY-rich, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" } ], "pathwayXRefs" : [ { "name" : "PKMTs methylate histone lysines", "databaseName" : "Reactome", "id" : "R-HSA-3214841" }, { "name" : "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function", "databaseName" : "Reactome", "id" : "R-HSA-8936459" } ] } }, "locations" : [ { "start" : 1398, "end" : 1455, "score" : 16.414, "alignment" : "AVKLVVGSLHIHSLGKFEP--QVSDTSFAIIPIEFSCSRLFWSSSEPWKVIPYHIKTILI", "location-fragments" : [ { "start" : 1398, "end" : 1455, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51542" }, { "signature" : { "accession" : "PTHR45838", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1132, "end" : 1452, "hmmStart" : 1212, "hmmEnd" : 1553, "hmmLength" : 2450, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1117, "envelopeEnd" : 1519, "location-fragments" : [ { "start" : 1132, "end" : 1452, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-280, "familyName" : "HISTONE-LYSINE N-METHYLTRANSFERASE 2B", "score" : 935.7, "model-ac" : "PTHR45838" }, { "signature" : { "accession" : "SSF57903", "name" : "FYVE/PHD zinc finger", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011011", "name" : "Znf_FYVE_PHD", "description" : "Zinc finger, FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 879, "end" : 945, "hmmLength" : 79, "location-fragments" : [ { "start" : 879, "end" : 945, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.22E-9, "model-ac" : "0050470" }, { "signature" : { "accession" : "PS50016", "name" : "ZF_PHD_2", "description" : "Zinc finger PHD-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR019787", "name" : "Znf_PHD-finger", "description" : "Zinc finger, PHD-finger", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 747, "end" : 804, "score" : 9.143, "alignment" : "PALCFLCGSAG--VDRLVHCVSCCEAYHQYCVEMNMHpsklslDRNWWRVDWICPKCTFC", "location-fragments" : [ { "start" : 747, "end" : 804, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50016" }, { "signature" : { "accession" : "PS50016", "name" : "ZF_PHD_2", "description" : "Zinc finger PHD-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR019787", "name" : "Znf_PHD-finger", "description" : "Zinc finger, PHD-finger", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 801, "end" : 850, "score" : 9.882, "alignment" : "CTFCTVCND----PAPQLCCQRCLKSYHSNCLSPNRQRPHLTDKTWVCPSCLRC", "location-fragments" : [ { "start" : 801, "end" : 850, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50016" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 617, "end" : 691, "location-fragments" : [ { "start" : 617, "end" : 691, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 632, "end" : 649, "location-fragments" : [ { "start" : 632, "end" : 649, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00249", "name" : "PHD_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001965", "name" : "Znf_PHD", "description" : "Zinc finger, PHD-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 880, "end" : 937, "hmmStart" : 1, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-5, "score" : 34.8, "location-fragments" : [ { "start" : 880, "end" : 937, "dc-status" : "CONTINUOUS" } ] }, { "start" : 803, "end" : 848, "hmmStart" : 1, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-6, "score" : 36.2, "location-fragments" : [ { "start" : 803, "end" : 848, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1315, "end" : 1361, "hmmStart" : 1, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "COMPLETE", "evalue" : 0.0023, "score" : 27.2, "location-fragments" : [ { "start" : 1315, "end" : 1361, "dc-status" : "CONTINUOUS" } ] }, { "start" : 749, "end" : 802, "hmmStart" : 1, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-4, "score" : 31.0, "location-fragments" : [ { "start" : 749, "end" : 802, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-34, "score" : 129.1, "model-ac" : "SM00249" }, { "signature" : { "accession" : "PF05965", "name" : "FYRC", "description" : "F/Y rich C-terminus", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR003889", "name" : "FYrich_C", "description" : "FY-rich, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" } ], "pathwayXRefs" : [ { "name" : "PKMTs methylate histone lysines", "databaseName" : "Reactome", "id" : "R-HSA-3214841" }, { "name" : "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function", "databaseName" : "Reactome", "id" : "R-HSA-8936459" } ] } }, "locations" : [ { "start" : 2499, "end" : 2585, "hmmStart" : 1, "hmmEnd" : 84, "hmmLength" : 84, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-14, "score" : 54.2, "envelopeStart" : 2499, "envelopeEnd" : 2585, "postProcessed" : true, "location-fragments" : [ { "start" : 2499, "end" : 2585, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-15, "score" : 56.5, "model-ac" : "PF05965" }, { "signature" : { "accession" : "PS50868", "name" : "POST_SET", "description" : "Post-SET domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR003616", "name" : "Post-SET_dom", "description" : "Post-SET domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "PKMTs methylate histone lysines", "databaseName" : "Reactome", "id" : "R-HSA-3214841" } ] } }, "locations" : [ { "start" : 2790, "end" : 2806, "score" : 8.43, "alignment" : "DKISCHCLSRKCRKYLN", "location-fragments" : [ { "start" : 2790, "end" : 2806, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50868" }, { "signature" : { "accession" : "SSF82199", "name" : "SET domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 2669, "end" : 2803, "hmmLength" : 284, "location-fragments" : [ { "start" : 2669, "end" : 2803, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.66E-46, "model-ac" : "0048183" }, { "signature" : { "accession" : "G3DSA:3.30.40.10", "name" : "Zinc/RING finger domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013083", "name" : "Znf_RING/FYVE/PHD", "description" : "Zinc finger, RING/FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 745, "end" : 802, "hmmStart" : 10, "hmmEnd" : 52, "hmmLength" : 56, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.4E-5, "score" : 26.7, "envelopeStart" : 745, "envelopeEnd" : 803, "postProcessed" : true, "location-fragments" : [ { "start" : 745, "end" : 802, "dc-status" : "CONTINUOUS" } ] }, { "start" : 803, "end" : 850, "hmmStart" : 10, "hmmEnd" : 52, "hmmLength" : 56, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.1E-7, "score" : 32.0, "envelopeStart" : 802, "envelopeEnd" : 850, "postProcessed" : true, "location-fragments" : [ { "start" : 803, "end" : 850, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-10, "score" : 42.1, "model-ac" : "2md7B00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1549, "end" : 1574, "location-fragments" : [ { "start" : 1549, "end" : 1574, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00856", "name" : "SET", "description" : "SET domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001214", "name" : "SET_dom", "description" : "SET domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2679, "end" : 2783, "hmmStart" : 1, "hmmEnd" : 168, "hmmLength" : 169, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.6E-24, "score" : 85.2, "envelopeStart" : 2679, "envelopeEnd" : 2784, "postProcessed" : true, "location-fragments" : [ { "start" : 2679, "end" : 2783, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-24, "score" : 85.2, "model-ac" : "PF00856" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 2466, "end" : 2486, "location-fragments" : [ { "start" : 2466, "end" : 2486, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR45838", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 632, "end" : 974, "hmmStart" : 859, "hmmEnd" : 1197, "hmmLength" : 2450, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 617, "envelopeEnd" : 995, "location-fragments" : [ { "start" : 632, "end" : 974, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-280, "familyName" : "HISTONE-LYSINE N-METHYLTRANSFERASE 2B", "score" : 935.7, "model-ac" : "PTHR45838" }, { "signature" : { "accession" : "SM00317", "name" : "set_7", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001214", "name" : "SET_dom", "description" : "SET domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2668, "end" : 2790, "hmmStart" : 1, "hmmEnd" : 114, "hmmLength" : 114, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-43, "score" : 159.7, "location-fragments" : [ { "start" : 2668, "end" : 2790, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-43, "score" : 159.7, "model-ac" : "SM00317" } ], "xref" : [ { "name" : "XP_018910042.1 PREDICTED: histone-lysine N-methyltransferase trithorax-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910042.1" } ] },{ "sequence" : "MASVSVMLSMVLQTYSVSVVSMAHSLHLLGFPPRKVRSRKNKENMESTDSPESTEMESTKGTESTKKTRRTKSTKGKKRTRSTKTKSTESKKPKSTRSTKTKSTKITKTKKNTKTPKIKKSARNTRLPRISKSTESTKISKTTEVIGSTEILTTTRHETTRSRPKIISPFDAIFRENEIVPQIVNNTPIYKCEVEYGKEKIHFGNNMTADQIAEKPTLIKWPTQSGAFYTLLMFGFHRILFFIYKQPGRRRLNFTSSKGVIKKGSKWEVRGVWYIERFLAKFNLTEPIAANFFFLYDLNPHPEIPHVTVDPLSLIR", "md5" : "63a448a3478f4f84ba0b683e017e44c7", "matches" : [ { "signature" : { "accession" : "PTHR11362", "name" : "PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR035810", "name" : "PEBP_euk", "description" : "Phosphatidylethanolamine-binding protein, eukaryotic", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 235, "end" : 294, "hmmStart" : 119, "hmmEnd" : 173, "hmmLength" : 193, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 234, "envelopeEnd" : 308, "location-fragments" : [ { "start" : 235, "end" : 294, "dc-status" : "CONTINUOUS" } ] }, { "start" : 170, "end" : 235, "hmmStart" : 8, "hmmEnd" : 73, "hmmLength" : 193, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 163, "envelopeEnd" : 236, "location-fragments" : [ { "start" : 170, "end" : 235, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-19, "familyName" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "score" : 71.9, "model-ac" : "PTHR11362" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 97, "end" : 126, "location-fragments" : [ { "start" : 97, "end" : 126, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 70, "end" : 85, "location-fragments" : [ { "start" : 70, "end" : 85, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.90.280.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 169, "end" : 234, "hmmStart" : 12, "hmmEnd" : 72, "hmmLength" : 190, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.4E-9, "score" : 38.1, "envelopeStart" : 169, "envelopeEnd" : 235, "postProcessed" : true, "location-fragments" : [ { "start" : 169, "end" : 234, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-19, "score" : 70.3, "model-ac" : "2iqyA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 127, "end" : 142, "location-fragments" : [ { "start" : 127, "end" : 142, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.90.280.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 235, "end" : 297, "hmmStart" : 122, "hmmEnd" : 170, "hmmLength" : 180, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 6.4E-7, "score" : 31.1, "envelopeStart" : 234, "envelopeEnd" : 297, "postProcessed" : true, "location-fragments" : [ { "start" : 235, "end" : 297, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-19, "score" : 69.8, "model-ac" : "1wkoA00" }, { "signature" : { "accession" : "SSF49777", "name" : "PEBP-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 174, "end" : 294, "hmmLength" : 185, "location-fragments" : [ { "start" : 174, "end" : 294, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.49E-13, "model-ac" : "0034862" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 37, "end" : 142, "location-fragments" : [ { "start" : 37, "end" : 142, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR11362:SF28", "name" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 235, "end" : 294, "hmmStart" : 119, "hmmEnd" : 173, "hmmLength" : 193, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 234, "envelopeEnd" : 308, "location-fragments" : [ { "start" : 235, "end" : 294, "dc-status" : "CONTINUOUS" } ] }, { "start" : 170, "end" : 235, "hmmStart" : 8, "hmmEnd" : 73, "hmmLength" : 193, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 163, "envelopeEnd" : 236, "location-fragments" : [ { "start" : 170, "end" : 235, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-19, "familyName" : "PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN 1", "score" : 71.9, "model-ac" : "PTHR11362:SF28" } ], "xref" : [ { "name" : "XP_018910113.1 PREDICTED: uncharacterized protein LOC109039182 isoform X3 [Bemisia tabaci]", "id" : "XP_018910113.1" } ] },{ "sequence" : "MFDSLVFLAVTLSIFCLIKVAEPASYYGYHPTDKHEVDAPHHEPHYEHDLKYEFGYRVHDPHYHNYQERAEAGGGDDVEGYYSFLEPNGFIRIVKYSSDKHGFRADVAHHVPSGKKEIKHGKSDSYFPQKNKHAKQSPDYPYV", "md5" : "bed19e18ea9786db3b5825155f526761", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 113, "end" : 143, "location-fragments" : [ { "start" : 113, "end" : 143, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51155", "name" : "CHIT_BIND_RR_2", "description" : "Chitin-binding type R&R domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000618", "name" : "Insect_cuticle", "description" : "Insect cuticle protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of cuticle", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0042302" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 49, "end" : 115, "score" : 15.517, "alignment" : "DLKYEFGYRVHDPHYHNYQERaEAGGGDD--VEGYYSFLEPNGFIRIVKYSSDKHGFRADVAHHVPSGK", "location-fragments" : [ { "start" : 49, "end" : 115, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51155" }, { "signature" : { "accession" : "PF00379", "name" : "Chitin_bind_4", "description" : "Insect cuticle protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000618", "name" : "Insect_cuticle", "description" : "Insect cuticle protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of cuticle", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0042302" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 52, "end" : 103, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 2.0E-10, "score" : 41.0, "envelopeStart" : 52, "envelopeEnd" : 103, "postProcessed" : true, "location-fragments" : [ { "start" : 52, "end" : 103, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-10, "score" : 42.0, "model-ac" : "PF00379" }, { "signature" : { "accession" : "PTHR12236", "name" : "STRUCTURAL CONTITUENT OF CUTICLE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 137, "hmmStart" : 8, "hmmEnd" : 144, "hmmLength" : 190, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 143, "location-fragments" : [ { "start" : 14, "end" : 137, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-21, "familyName" : "STRUCTURAL CONTITUENT OF CUTICLE", "score" : 77.3, "model-ac" : "PTHR12236" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 113, "end" : 129, "location-fragments" : [ { "start" : 113, "end" : 129, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910369.1 PREDICTED: cuticle protein 8-like [Bemisia tabaci]", "id" : "XP_018910369.1" } ] },{ "sequence" : "MFSKTLVRTYNSFLTQKTAFKFLSTSSSEVSVKSVPEWKSKQIALFDKELKRQQEAVGRIEKIKVQYRGTPEDVLLSMNKGVSTPFHCAQHMSEMLTKRSALAMVDGTELWDMHRPLEKDCEIQLLHFQDPDPFQVNRAFWRTCSLLLGGVISNAFKEDIQVNLHSFPSPNVRSGSFVYDVQIPELTDWKPTQDELRILSADMVIMSRKDLPLQRLAVKEDVAQELFSHNKFKLEQIPSILEQAPDKRVIVYRVGDHMDISRGPMVGSTQFIGRCTVASVHQIENDNLHLYRFQGVALPKGIFLNHFAYGVLEDRARRLNSSLYSGQILTETFKPNLEEKAAN", "md5" : "aff797c092c9a7cc1882f08c09635157", "matches" : [ { "signature" : { "accession" : "G3DSA:3.30.980.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 135, "end" : 298, "hmmStart" : 6, "hmmEnd" : 156, "hmmLength" : 158, "hmmBounds" : "COMPLETE", "evalue" : 6.8E-27, "score" : 96.4, "envelopeStart" : 135, "envelopeEnd" : 298, "postProcessed" : true, "location-fragments" : [ { "start" : 135, "end" : 298, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-27, "score" : 97.2, "model-ac" : "1nyrB02" }, { "signature" : { "accession" : "G3DSA:3.10.20.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012675", "name" : "Beta-grasp_dom_sf", "description" : "Beta-grasp domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 62, "end" : 126, "hmmStart" : 14, "hmmEnd" : 62, "hmmLength" : 62, "hmmBounds" : "COMPLETE", "evalue" : 8.8E-14, "score" : 53.5, "envelopeStart" : 62, "envelopeEnd" : 126, "postProcessed" : true, "location-fragments" : [ { "start" : 62, "end" : 126, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-14, "score" : 55.1, "model-ac" : "1wwtA01" }, { "signature" : { "accession" : "PTHR42753:SF9", "name" : "39S RIBOSOMAL PROTEIN L39, MITOCHONDRIAL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 327, "hmmStart" : 9, "hmmEnd" : 328, "hmmLength" : 341, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 341, "location-fragments" : [ { "start" : 9, "end" : 327, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-115, "familyName" : "39S RIBOSOMAL PROTEIN L39, MITOCHONDRIAL", "score" : 388.2, "model-ac" : "PTHR42753:SF9" }, { "signature" : { "accession" : "SSF55186", "name" : "ThrRS/AlaRS common domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR018163", "name" : "Thr/Ala-tRNA-synth_IIc_edit", "description" : "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0000166" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 135, "end" : 308, "hmmLength" : 179, "location-fragments" : [ { "start" : 135, "end" : 308, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.12E-22, "model-ac" : "0041633" }, { "signature" : { "accession" : "PTHR42753", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 327, "hmmStart" : 9, "hmmEnd" : 328, "hmmLength" : 341, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 341, "location-fragments" : [ { "start" : 9, "end" : 327, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-115, "familyName" : "39S RIBOSOMAL PROTEIN L39, MITOCHONDRIAL", "score" : 388.2, "model-ac" : "PTHR42753" }, { "signature" : { "accession" : "PF02824", "name" : "TGS", "description" : "TGS domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004095", "name" : "TGS", "description" : "TGS", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Aminoacyl-tRNA biosynthesis", "databaseName" : "KEGG", "id" : "00970+6.1.1.3" } ] } }, "locations" : [ { "start" : 80, "end" : 126, "hmmStart" : 15, "hmmEnd" : 59, "hmmLength" : 60, "hmmBounds" : "INCOMPLETE", "evalue" : 2.9E-6, "score" : 27.2, "envelopeStart" : 65, "envelopeEnd" : 127, "postProcessed" : true, "location-fragments" : [ { "start" : 80, "end" : 126, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-7, "score" : 30.2, "model-ac" : "PF02824" }, { "signature" : { "accession" : "cd01667", "name" : "TGS_ThrRS", "description" : "TGS_ThrRS", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 63, "end" : 132, "sites" : [ ], "evalue" : 8.41178E-18, "score" : 74.4465, "location-fragments" : [ { "start" : 63, "end" : 132, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01667" } ], "xref" : [ { "name" : "XP_018909904.1 PREDICTED: 39S ribosomal protein L39, mitochondrial [Bemisia tabaci]", "id" : "XP_018909904.1" } ] },{ "sequence" : "MYTNIPIKLALNVITEKWPLIVPHTTLPKEQFLEGIRACLDSTIFKFGEDCYKRIDGLAMGGPVSASVANLVMEYFEEKMFEVFPYKTLFYKRFADDIILCCHKDDLNSIYQFFNMFSSNIKFSIEYEANNAIAFLDVLVIKQGSKFVTSWFTKPTFSGRYLNFLSAQPLSQKINVIKNLARRVCLLTHPMLRKEKIREAKKLLFENCYPKHRVNSIFENVVKFCYDGFPPPKLFEKTEFVVRPYVSSCSEKIRSVLKPHGYTLVTSNKSNLQNFQSCSKSKIPTEKLSGVVYEIPCGDCQGIYIGQSSQYLHKRLDGHKFNQHEVTALKQHMREKGHSFDFNNTRVLKRERNEQIRLNLEGLCILNNQNAVNSRTEFAHFEEYFSNL", "md5" : "d39a393998f9b680783695ba4d074742", "matches" : [ { "signature" : { "accession" : "PTHR21301", "name" : "REVERSE TRANSCRIPTASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 280, "hmmStart" : 427, "hmmEnd" : 680, "hmmLength" : 762, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 363, "location-fragments" : [ { "start" : 24, "end" : 280, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-18, "familyName" : "", "score" : 68.0, "model-ac" : "PTHR21301" }, { "signature" : { "accession" : "SSF56672", "name" : "DNA/RNA polymerases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR043502", "name" : "DNA/RNA_pol_sf", "description" : "DNA/RNA polymerase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 36, "end" : 124, "hmmLength" : 460, "location-fragments" : [ { "start" : 36, "end" : 124, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.25E-7, "model-ac" : "0051077" }, { "signature" : { "accession" : "PTHR21301:SF7", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 280, "hmmStart" : 427, "hmmEnd" : 680, "hmmLength" : 762, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 363, "location-fragments" : [ { "start" : 24, "end" : 280, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-18, "familyName" : "", "score" : 68.0, "model-ac" : "PTHR21301:SF7" } ], "xref" : [ { "name" : "XP_018910560.1 PREDICTED: uncharacterized protein LOC109039515 [Bemisia tabaci]", "id" : "XP_018910560.1" } ] },{ "sequence" : "MAEFSNPDSSNLPLNRLVRVGYYKLERTIGKGNFAIVKLATHVVTNSQVAIKIIDKTKLDEDNLKNIFREIKIMSVLHHPHIIRLYQVMETNKVIYLVTEYASGGEIFDHLVANGSMSEKEACRMFHQILSAISYCHHKKIVHRDIKAENLLLDENMNIKLADFGFSNYFDDQLMSTWCGSPPYAAPELFTGKKYDGPRADIWSLGVVLYVLVCGVLPFDGKTLESLRTRVINGKFRIPFFMSADCEHLIRHMLVVDPEKRLSIAQIRKHQWMARLKDDSEELIWEDKPCTNHPPLNQSVIQHMLQLPGLDREKIINSVQQLQFDHISAIYHLIVDKLQKNESKTPINSHKHDSTEGCEEQGFSMPLVSMPMLPHLSMVQDPQLLEKFGDVDIESDKKDIPNSVDDKYQLTTRRHTVGPGDSCHTQLLETHYLTCGQREIPNILPNTNLPLNLPLVQNQPPRNFTIKDQHLLKPPPVMGANANGFGRRASDGGANLKMYYQRLDGVCSQPGSNEELQLQPGSPTIAQRSQPLNTSAIPSIEAISQVSADLIGSNSEDVSPELLSRYIQNCGGTKRHSLGLGCTEEILGQHQSQSTSRTRRSGLLTVTERPPVISPELIQEVETRMRRKYTPPPLPLLSTSLRHPRILPQAPVLPTVQESQRVSVGRESLKESSSSYLVQERYSPVRRASEGTPCNHEASESSLKIIQQEYQLLQKSSGNSLDSRVQAELQQKHMQHLLTVKPPSPSSPLSGLPYVTQGSMNLTHHMQSLHLQQSNSSPLSTPRLSPSPPSTSPTHGANVGSISQGTAIQQQMSPLDLRVTHSPPNSQLQLTIIEEEHNGPQRVQLSTNPQISVTDELGSLVPLEDDIPMDCCPDSYISPTETVPCFVISPCDLTQPSITRGIGRSQNSHQHSISSQESEYPDQKNSLYSKSFLEFNENINENELNCKKFPVFAADLHKTSSGSFEVALSDVCSRLGAPEIVNLIKKAVNAQVRHNVLEFPTGLQIELEVRSTISGSSQLKIRRVSGDLGEYDALCYHLVTAMSA", "md5" : "cfbcca12402afaa3df7477f90dd7a25d", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 722, "end" : 822, "location-fragments" : [ { "start" : 722, "end" : 822, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 20, "end" : 792, "hmmLength" : 364, "location-fragments" : [ { "start" : 20, "end" : 274, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 731, "end" : 792, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.15E-96, "model-ac" : "0041927" }, { "signature" : { "accession" : "PF00069", "name" : "Pkinase", "description" : "Protein kinase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 23, "end" : 273, "hmmStart" : 1, "hmmEnd" : 264, "hmmLength" : 264, "hmmBounds" : "COMPLETE", "evalue" : 5.6E-74, "score" : 248.8, "envelopeStart" : 23, "envelopeEnd" : 273, "postProcessed" : true, "location-fragments" : [ { "start" : 23, "end" : 273, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-74, "score" : 249.7, "model-ac" : "PF00069" }, { "signature" : { "accession" : "PTHR24343:SF342", "name" : "NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 6, "end" : 346, "hmmStart" : 24, "hmmEnd" : 384, "hmmLength" : 1471, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 370, "location-fragments" : [ { "start" : 6, "end" : 346, "dc-status" : "CONTINUOUS" } ] }, { "start" : 446, "end" : 500, "hmmStart" : 521, "hmmEnd" : 573, "hmmLength" : 1471, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 431, "envelopeEnd" : 502, "location-fragments" : [ { "start" : 446, "end" : 500, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-195, "familyName" : "NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE", "score" : 653.8, "model-ac" : "PTHR24343:SF342" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 899, "end" : 920, "location-fragments" : [ { "start" : 899, "end" : 920, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS00108", "name" : "PROTEIN_KINASE_ST", "description" : "Serine/Threonine protein kinases active-site signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR008271", "name" : "Ser/Thr_kinase_AS", "description" : "Serine/threonine-protein kinase, active site", "type" : "ACTIVE_SITE", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 141, "end" : 153, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I3M2I4M", "alignment" : "IvHrDIKaeNLLL", "location-fragments" : [ { "start" : 141, "end" : 153, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00108" }, { "signature" : { "accession" : "SM00220", "name" : "serkin_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 23, "end" : 273, "hmmStart" : 1, "hmmEnd" : 231, "hmmLength" : 231, "hmmBounds" : "COMPLETE", "evalue" : 9.8E-103, "score" : 357.3, "location-fragments" : [ { "start" : 23, "end" : 273, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.8E-103, "score" : 357.3, "model-ac" : "SM00220" }, { "signature" : { "accession" : "PTHR24343", "name" : "SERINE/THREONINE KINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 6, "end" : 346, "hmmStart" : 24, "hmmEnd" : 384, "hmmLength" : 1471, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 370, "location-fragments" : [ { "start" : 6, "end" : 346, "dc-status" : "CONTINUOUS" } ] }, { "start" : 446, "end" : 500, "hmmStart" : 521, "hmmEnd" : 573, "hmmLength" : 1471, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 431, "envelopeEnd" : 502, "location-fragments" : [ { "start" : 446, "end" : 500, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-195, "familyName" : "NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE", "score" : 653.8, "model-ac" : "PTHR24343" }, { "signature" : { "accession" : "cd14338", "name" : "UBA_SIK", "description" : "UBA_SIK", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 297, "end" : 341, "sites" : [ ], "evalue" : 2.23596E-13, "score" : 63.3104, "location-fragments" : [ { "start" : 297, "end" : 341, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd14338" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 740, "end" : 781, "location-fragments" : [ { "start" : 740, "end" : 781, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 790, "end" : 822, "location-fragments" : [ { "start" : 790, "end" : 822, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS00107", "name" : "PROTEIN_KINASE_ATP", "description" : "Protein kinases ATP-binding region signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017441", "name" : "Protein_kinase_ATP_BS", "description" : "Protein kinase, ATP binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 29, "end" : 52, "level" : "STRONG", "cigarAlignment" : "10M1I1M8I4M", "alignment" : "IGKGNFAIVKlAthvvtnsqVAIK", "location-fragments" : [ { "start" : 29, "end" : 52, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00107" }, { "signature" : { "accession" : "G3DSA:1.10.510.10", "name" : "Transferase(Phosphotransferase) domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 17, "end" : 358, "hmmStart" : 10, "hmmEnd" : 332, "hmmLength" : 347, "hmmBounds" : "COMPLETE", "evalue" : 3.8E-114, "score" : 383.4, "envelopeStart" : 17, "envelopeEnd" : 358, "postProcessed" : true, "location-fragments" : [ { "start" : 17, "end" : 358, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-114, "score" : 384.4, "model-ac" : "4bkyA00" }, { "signature" : { "accession" : "PS50011", "name" : "PROTEIN_KINASE_DOM", "description" : "Protein kinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 23, "end" : 273, "score" : 50.887, "alignment" : "YKLERTIGKGNFAIVKLATHVVTNSQVAIKIIDKTKLDEDNLKNIFREIKIMSVLHHPHIIRLYQVMETNKVIYLVTEYASGGEIFDHLVANGS-MSEKEACRMFHQILSAISYCHHKKIVHRDIKAENLLLDENMNIKLADFGFSNYFDD--QLMSTWCGSPPYAAPELFTGKKYDGPRADIWSLGVVLYVLVCGVLPFDG-KTLESLRTRVING----------KfripffMSADCEHLIRHMLVVDPEKRLSIAQIRKHQWM", "location-fragments" : [ { "start" : 23, "end" : 273, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50011" } ], "xref" : [ { "name" : "XP_018910219.1 PREDICTED: serine/threonine-protein kinase SIK3-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910219.1" } ] },{ "sequence" : "MPRKYTKKRPPKPYTEVDLQNALKDVQSGKLKLLAAASNYNIPSSTLSDHLSNKVKFQGSIGGGRNQVLDTKTEQTIAECLLARALLGCPCSKDEMLQLVREYVTNNELVTPFNNNLPGDDWYRNFMKRHPQLSLKKPEQLQKARVKARDPDVYNFYDIVKKEYDEFKMHEHPSFVFNCDETPLPSDPSKSRAIGEKGVALSRVS", "md5" : "1c2a2936b79f812c6cbe6fe4db0a8db9", "matches" : [ { "signature" : { "accession" : "PS50960", "name" : "HTH_PSQ", "description" : "Psq-type HTH domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR007889", "name" : "HTH_Psq", "description" : "DNA binding HTH domain, Psq-type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 57, "score" : 16.091, "alignment" : "MPrkytKKRPPKPYTEVDLQNALKDVQSGKLKLLAAASNYNIPSSTLSDHLSNKVKF", "location-fragments" : [ { "start" : 1, "end" : 57, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50960" }, { "signature" : { "accession" : "SSF46689", "name" : "Homeodomain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009057", "name" : "Homeobox-like_sf", "description" : "Homeobox-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 56, "hmmLength" : 63, "location-fragments" : [ { "start" : 10, "end" : 56, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.69E-9, "model-ac" : "0052194" }, { "signature" : { "accession" : "G3DSA:1.10.10.60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 58, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 44, "hmmBounds" : "COMPLETE", "evalue" : 9.1E-9, "score" : 36.6, "envelopeStart" : 14, "envelopeEnd" : 58, "postProcessed" : true, "location-fragments" : [ { "start" : 14, "end" : 58, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-9, "score" : 37.6, "model-ac" : "2cobA01" }, { "signature" : { "accession" : "PTHR19303", "name" : "TRANSPOSON", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 198, "hmmStart" : 266, "hmmEnd" : 466, "hmmLength" : 792, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 203, "location-fragments" : [ { "start" : 2, "end" : 198, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-15, "familyName" : "", "score" : 58.6, "model-ac" : "PTHR19303" }, { "signature" : { "accession" : "PF05225", "name" : "HTH_psq", "description" : "helix-turn-helix, Psq domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR007889", "name" : "HTH_Psq", "description" : "DNA binding HTH domain, Psq-type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 18, "end" : 54, "hmmStart" : 4, "hmmEnd" : 40, "hmmLength" : 45, "hmmBounds" : "INCOMPLETE", "evalue" : 1.3E-5, "score" : 24.8, "envelopeStart" : 15, "envelopeEnd" : 58, "postProcessed" : true, "location-fragments" : [ { "start" : 18, "end" : 54, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.1E-6, "score" : 25.9, "model-ac" : "PF05225" }, { "signature" : { "accession" : "PTHR19303:SF39", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 198, "hmmStart" : 266, "hmmEnd" : 466, "hmmLength" : 792, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 203, "location-fragments" : [ { "start" : 2, "end" : 198, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-15, "familyName" : "", "score" : 58.6, "model-ac" : "PTHR19303:SF39" } ], "xref" : [ { "name" : "XP_018910205.1 PREDICTED: uncharacterized protein LOC109039246, partial [Bemisia tabaci]", "id" : "XP_018910205.1" } ] },{ "sequence" : "MAPTKRSKSNSRASSANTGPRNSERRNAARNNSNEAGSSHDSIITGRVTRSSVRSSQPSTSSGIHSLAPSRRAPIASSTACRIATNVFQTMNNVIRASSSISRLAAEQAVGSSPNPDASSSSDNESNPEVDLVPTIPEGGPFRQGDFKSVYDYLSTIQKRLLYINKRLDSLLEKCKSLYIPRDPRVSRTEICENANIDVANYNTSRLVCPVCYCDLLRAEAAPLSTKCGHIFCSACLIQIMVMDESKCPNCRKPLTTTDYHPVFFPQLLS", "md5" : "45f158699212288b62bd66ca22ed34d8", "matches" : [ { "signature" : { "accession" : "PS50089", "name" : "ZF_RING_2", "description" : "Zinc finger RING-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 209, "end" : 252, "score" : 12.091, "alignment" : "CPVCYCDLLRAeaAPLSTKCGHIFCSACLIQI-MVMDESKCPNCR", "location-fragments" : [ { "start" : 209, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50089" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 106, "end" : 137, "location-fragments" : [ { "start" : 106, "end" : 137, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.40.10", "name" : "Zinc/RING finger domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013083", "name" : "Znf_RING/FYVE/PHD", "description" : "Zinc finger, RING/FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 192, "end" : 266, "hmmStart" : 17, "hmmEnd" : 74, "hmmLength" : 75, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-13, "score" : 51.4, "envelopeStart" : 192, "envelopeEnd" : 266, "postProcessed" : true, "location-fragments" : [ { "start" : 192, "end" : 266, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-13, "score" : 52.5, "model-ac" : "5trbA00" }, { "signature" : { "accession" : "PF13639", "name" : "zf-RING_2", "description" : "Ring finger domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 209, "end" : 252, "hmmStart" : 3, "hmmEnd" : 44, "hmmLength" : 44, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.6E-8, "score" : 34.8, "envelopeStart" : 207, "envelopeEnd" : 252, "postProcessed" : true, "location-fragments" : [ { "start" : 209, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-9, "score" : 35.6, "model-ac" : "PF13639" }, { "signature" : { "accession" : "PS00518", "name" : "ZF_RING_1", "description" : "Zinc finger RING-type signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017907", "name" : "Znf_RING_CS", "description" : "Zinc finger, RING-type, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 228, "end" : 237, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I2M2I2M", "alignment" : "CgHiFCsaCL", "location-fragments" : [ { "start" : 228, "end" : 237, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00518" }, { "signature" : { "accession" : "SM00184", "name" : "ring_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 209, "end" : 251, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 3.1E-5, "score" : 33.4, "location-fragments" : [ { "start" : 209, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-5, "score" : 33.4, "model-ac" : "SM00184" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 67, "location-fragments" : [ { "start" : 1, "end" : 67, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57850", "name" : "RING/U-box", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 208, "end" : 258, "hmmLength" : 114, "location-fragments" : [ { "start" : 208, "end" : 258, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.14E-13, "model-ac" : "0050087" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 106, "end" : 129, "location-fragments" : [ { "start" : 106, "end" : 129, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR23041", "name" : "RING FINGER DOMAIN-CONTAINING", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 37, "end" : 265, "hmmStart" : 58, "hmmEnd" : 235, "hmmLength" : 235, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 2, "envelopeEnd" : 265, "location-fragments" : [ { "start" : 37, "end" : 265, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-15, "familyName" : "RING FINGER DOMAIN-CONTAINING", "score" : 61.0, "model-ac" : "PTHR23041" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 70, "location-fragments" : [ { "start" : 1, "end" : 70, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910466.1 PREDICTED: uncharacterized protein LOC109039442 isoform X1 [Bemisia tabaci]", "id" : "XP_018910466.1" } ] },{ "sequence" : "MQEIFPMLLFPGSGHCTPTIYPANPFDANADAEVLRKAMKGFGTDEAAIIEVLGRRGIVQRLEIAEAFKTLYGKDLIDDLKSELSGKFERVILALLTPLPLYYAKELHDAIAGLGTDEGAIIEILCTLSNYGIKTIASFYEKEYEKSLEKDLKGDTSGHFQRLLVSLVQANRDESVDVDQAQVLKDAEDLHAAGVEKSWGTDESVFNSVLATRSYNHLREVFNQYAVIAGHDIEEAISSEFSGSVGKGLLAIAKVVRSKVTYFAERLHDSMAGAGTDDRTLIRIIVSRSEIDLGDIKAAFEEKYGQTLESWIADDTSGDYKKILLKVVQS", "md5" : "cc9d23e75b1149511eb4e204b9efbb1b", "matches" : [ { "signature" : { "accession" : "SM00335", "name" : "annex3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR018502", "name" : "Annexin_repeat", "description" : "Annexin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 115, "end" : 167, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-22, "score" : 90.8, "location-fragments" : [ { "start" : 115, "end" : 167, "dc-status" : "CONTINUOUS" } ] }, { "start" : 43, "end" : 95, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 4.1E-24, "score" : 96.1, "location-fragments" : [ { "start" : 43, "end" : 95, "dc-status" : "CONTINUOUS" } ] }, { "start" : 275, "end" : 327, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 6.5E-22, "score" : 88.8, "location-fragments" : [ { "start" : 275, "end" : 327, "dc-status" : "CONTINUOUS" } ] }, { "start" : 200, "end" : 252, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 3.5E-15, "score" : 66.4, "location-fragments" : [ { "start" : 200, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-98, "score" : 342.2, "model-ac" : "SM00335" }, { "signature" : { "accession" : "SSF47874", "name" : "Annexin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 17, "end" : 329, "hmmLength" : 318, "location-fragments" : [ { "start" : 17, "end" : 329, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.26E-117, "model-ac" : "0053100" }, { "signature" : { "accession" : "PTHR10502:SF184", "name" : "ANNEXIN B9", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 328, "hmmStart" : 10, "hmmEnd" : 322, "hmmLength" : 324, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 10, "envelopeEnd" : 330, "location-fragments" : [ { "start" : 15, "end" : 328, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-154, "familyName" : "ANNEXIN B9", "score" : 515.1, "model-ac" : "PTHR10502:SF184" }, { "signature" : { "accession" : "PS00223", "name" : "ANNEXIN_1", "description" : "Annexin repeat signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018252", "name" : "Annexin_repeat_CS", "description" : "Annexin repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 275, "end" : 327, "level" : "STRONG", "cigarAlignment" : "2M8I1M2I1M3I1M2I1M4I1M7I1M3I1M5I1M5I1M2I1M", "alignment" : "GTddrtliriIvsRseiDlgDikaaFeekygqtLeswIaddtsGdykkiLlkV", "location-fragments" : [ { "start" : 275, "end" : 327, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00223" }, { "signature" : { "accession" : "PS00223", "name" : "ANNEXIN_1", "description" : "Annexin repeat signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018252", "name" : "Annexin_repeat_CS", "description" : "Annexin repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 43, "end" : 95, "level" : "STRONG", "cigarAlignment" : "2M8I1M2I1M3I1M2I1M4I1M7I1M3I1M5I1M5I1M2I1M", "alignment" : "GTdeaaiievLgrRgivQrlEiaeaFktlygkdLiddLkselsGkfervIlaL", "location-fragments" : [ { "start" : 43, "end" : 95, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00223" }, { "signature" : { "accession" : "PS51897", "name" : "ANNEXIN_2", "description" : "Annexin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 258, "end" : 329, "score" : 28.046, "alignment" : "SKVTYFAERLHDSMAGAGTDDRTLIRIIVSRSEIDLGDIKAAFEEKYGQTLESWIADDTSGDYKKILLKVVQ", "location-fragments" : [ { "start" : 258, "end" : 329, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51897" }, { "signature" : { "accession" : "PS51897", "name" : "ANNEXIN_2", "description" : "Annexin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 26, "end" : 97, "score" : 30.169, "alignment" : "FDANADAEVLRKAMKGFGTDEAAIIEVLGRRGIVQRLEIAEAFKTLYGKDLIDDLKSELSGKFERVILALLT", "location-fragments" : [ { "start" : 26, "end" : 97, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51897" }, { "signature" : { "accession" : "G3DSA:1.10.220.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 172, "end" : 258, "hmmStart" : 1, "hmmEnd" : 84, "hmmLength" : 86, "hmmBounds" : "COMPLETE", "evalue" : 3.3E-26, "score" : 93.2, "envelopeStart" : 172, "envelopeEnd" : 258, "postProcessed" : true, "location-fragments" : [ { "start" : 172, "end" : 258, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-94, "score" : 312.1, "model-ac" : "1hm6A03" }, { "signature" : { "accession" : "PF00191", "name" : "Annexin", "description" : "Annexin", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018502", "name" : "Annexin_repeat", "description" : "Annexin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 262, "end" : 326, "hmmStart" : 1, "hmmEnd" : 65, "hmmLength" : 66, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.1E-22, "score" : 79.8, "envelopeStart" : 262, "envelopeEnd" : 327, "postProcessed" : true, "location-fragments" : [ { "start" : 262, "end" : 326, "dc-status" : "CONTINUOUS" } ] }, { "start" : 102, "end" : 167, "hmmStart" : 1, "hmmEnd" : 66, "hmmLength" : 66, "hmmBounds" : "COMPLETE", "evalue" : 7.4E-23, "score" : 80.4, "envelopeStart" : 102, "envelopeEnd" : 167, "postProcessed" : true, "location-fragments" : [ { "start" : 102, "end" : 167, "dc-status" : "CONTINUOUS" } ] }, { "start" : 186, "end" : 252, "hmmStart" : 2, "hmmEnd" : 66, "hmmLength" : 66, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.4E-19, "score" : 67.6, "envelopeStart" : 185, "envelopeEnd" : 252, "postProcessed" : true, "location-fragments" : [ { "start" : 186, "end" : 252, "dc-status" : "CONTINUOUS" } ] }, { "start" : 31, "end" : 95, "hmmStart" : 2, "hmmEnd" : 66, "hmmLength" : 66, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.4E-24, "score" : 84.3, "envelopeStart" : 30, "envelopeEnd" : 95, "postProcessed" : true, "location-fragments" : [ { "start" : 31, "end" : 95, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-94, "score" : 310.4, "model-ac" : "PF00191" }, { "signature" : { "accession" : "G3DSA:1.10.220.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 260, "end" : 329, "hmmStart" : 3, "hmmEnd" : 70, "hmmLength" : 73, "hmmBounds" : "COMPLETE", "evalue" : 7.7E-28, "score" : 98.2, "envelopeStart" : 260, "envelopeEnd" : 329, "postProcessed" : true, "location-fragments" : [ { "start" : 260, "end" : 329, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-89, "score" : 293.8, "model-ac" : "1n00A03" }, { "signature" : { "accession" : "PS51897", "name" : "ANNEXIN_2", "description" : "Annexin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 98, "end" : 169, "score" : 27.54, "alignment" : "PLPLYYAKELHDAIAGLGTDEGAIIEILCTLSNYGIKTIASFYEKEYEKSLEKDLKGDTSGHFQRLLVSLVQ", "location-fragments" : [ { "start" : 98, "end" : 169, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51897" }, { "signature" : { "accession" : "PS51897", "name" : "ANNEXIN_2", "description" : "Annexin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 181, "end" : 254, "score" : 23.76, "alignment" : "AQVLKDAEDLHAAGVEksWGTDESVFNSVLATRSYNHLREVFNQYAVIAGHDIEEAISSEFSGSVGKGLLAIAK", "location-fragments" : [ { "start" : 181, "end" : 254, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51897" }, { "signature" : { "accession" : "PTHR10502", "name" : "ANNEXIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 328, "hmmStart" : 10, "hmmEnd" : 322, "hmmLength" : 324, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 10, "envelopeEnd" : 330, "location-fragments" : [ { "start" : 15, "end" : 328, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-154, "familyName" : "ANNEXIN B9", "score" : 515.1, "model-ac" : "PTHR10502" }, { "signature" : { "accession" : "G3DSA:1.10.220.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 25, "end" : 97, "hmmStart" : 2, "hmmEnd" : 72, "hmmLength" : 73, "hmmBounds" : "COMPLETE", "evalue" : 7.8E-29, "score" : 101.5, "envelopeStart" : 25, "envelopeEnd" : 97, "postProcessed" : true, "location-fragments" : [ { "start" : 25, "end" : 97, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-91, "score" : 302.4, "model-ac" : "1hm6A01" }, { "signature" : { "accession" : "G3DSA:1.10.220.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037104", "name" : "Annexin_sf", "description" : "Annexin superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 100, "end" : 171, "hmmStart" : 5, "hmmEnd" : 73, "hmmLength" : 74, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-26, "score" : 94.5, "envelopeStart" : 100, "envelopeEnd" : 171, "postProcessed" : true, "location-fragments" : [ { "start" : 100, "end" : 171, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-96, "score" : 318.3, "model-ac" : "1w3wA02" }, { "signature" : { "accession" : "PR00196", "name" : "ANNEXIN", "description" : "Annexin family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001464", "name" : "Annexin", "description" : "Annexin", "type" : "FAMILY", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" }, { "name" : "calcium-dependent phospholipid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005544" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 40, "end" : 62, "pvalue" : 9.1E-10, "score" : 51.05, "motifNumber" : 1, "location-fragments" : [ { "start" : 40, "end" : 62, "dc-status" : "CONTINUOUS" } ] }, { "start" : 191, "end" : 217, "pvalue" : 7.54E-10, "score" : 42.11, "motifNumber" : 4, "location-fragments" : [ { "start" : 191, "end" : 217, "dc-status" : "CONTINUOUS" } ] }, { "start" : 315, "end" : 328, "pvalue" : 2.55E-7, "score" : 59.92, "motifNumber" : 7, "location-fragments" : [ { "start" : 315, "end" : 328, "dc-status" : "CONTINUOUS" } ] }, { "start" : 107, "end" : 128, "pvalue" : 1.84E-10, "score" : 52.53, "motifNumber" : 3, "location-fragments" : [ { "start" : 107, "end" : 128, "dc-status" : "CONTINUOUS" } ] }, { "start" : 80, "end" : 96, "pvalue" : 5.08E-11, "score" : 64.27, "motifNumber" : 2, "location-fragments" : [ { "start" : 80, "end" : 96, "dc-status" : "CONTINUOUS" } ] }, { "start" : 271, "end" : 291, "pvalue" : 7.55E-14, "score" : 72.66, "motifNumber" : 5, "location-fragments" : [ { "start" : 271, "end" : 291, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-53, "graphscan" : "IIIII.I", "model-ac" : "PR00196" } ], "xref" : [ { "name" : "XP_018909638.1 PREDICTED: annexin B9 isoform X1 [Bemisia tabaci]", "id" : "XP_018909638.1" } ] },{ "sequence" : "MKIQLKMHMRTHTGEKPFSCSHCSASFSRKGTLKVHMRTHTFEKPFSCSHCTACFSHKKSLTEHVRTHTG", "md5" : "441f222516cf9e0d5e7331a5a5a0eca6", "matches" : [ { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 20, "end" : 40, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCsasFsrkgtlkvHmrtH", "location-fragments" : [ { "start" : 20, "end" : 40, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 48, "end" : 68, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M3I1M", "alignment" : "CshCtacFshkkslteHvrtH", "location-fragments" : [ { "start" : 48, "end" : 68, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 18, "end" : 45, "score" : 15.105, "alignment" : "FSCSHCSASFSRKGTLKVHMRTHTFEKP", "location-fragments" : [ { "start" : 18, "end" : 45, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 43, "end" : 70, "hmmStart" : 1, "hmmEnd" : 28, "hmmLength" : 28, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-10, "score" : 41.9, "envelopeStart" : 43, "envelopeEnd" : 70, "postProcessed" : true, "location-fragments" : [ { "start" : 43, "end" : 70, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-27, "score" : 96.2, "model-ac" : "2dlqA03" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 42, "hmmStart" : 1, "hmmEnd" : 31, "hmmLength" : 37, "hmmBounds" : "INCOMPLETE", "evalue" : 7.0E-14, "score" : 53.3, "envelopeStart" : 14, "envelopeEnd" : 43, "postProcessed" : true, "location-fragments" : [ { "start" : 19, "end" : 42, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-25, "score" : 90.1, "model-ac" : "2yrmA01" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 70, "score" : 13.069, "alignment" : "FSCSHCTACFSHKKSLTEHVRTHTG---", "location-fragments" : [ { "start" : 46, "end" : 70, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PTHR24409", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 70, "hmmStart" : 258, "hmmEnd" : 326, "hmmLength" : 387, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 70, "location-fragments" : [ { "start" : 2, "end" : 70, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-25, "familyName" : "SI:CABZ01054396.2-RELATED", "score" : 93.2, "model-ac" : "PTHR24409" }, { "signature" : { "accession" : "SM00355", "name" : "c2h2final6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 68, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.04, "score" : 23.1, "location-fragments" : [ { "start" : 46, "end" : 68, "dc-status" : "CONTINUOUS" } ] }, { "start" : 18, "end" : 40, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-4, "score" : 30.5, "location-fragments" : [ { "start" : 18, "end" : 40, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-11, "score" : 53.6, "model-ac" : "SM00355" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 55, "hmmLength" : 61, "location-fragments" : [ { "start" : 2, "end" : 55, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.93E-19, "model-ac" : "0050784" }, { "signature" : { "accession" : "PF00096", "name" : "zf-C2H2", "description" : "Zinc finger, C2H2 type", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 68, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.0031, "score" : 17.9, "envelopeStart" : 46, "envelopeEnd" : 68, "postProcessed" : true, "location-fragments" : [ { "start" : 46, "end" : 68, "dc-status" : "CONTINUOUS" } ] }, { "start" : 18, "end" : 40, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-6, "score" : 28.2, "envelopeStart" : 18, "envelopeEnd" : 40, "postProcessed" : true, "location-fragments" : [ { "start" : 18, "end" : 40, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-10, "score" : 40.5, "model-ac" : "PF00096" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 18, "hmmStart" : 17, "hmmEnd" : 33, "hmmLength" : 38, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 7.4E-8, "score" : 34.1, "envelopeStart" : 1, "envelopeEnd" : 21, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 18, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-24, "score" : 87.6, "model-ac" : "2eprA01" }, { "signature" : { "accession" : "PTHR24409:SF372", "name" : "SI:CABZ01054396.2-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 70, "hmmStart" : 258, "hmmEnd" : 326, "hmmLength" : 387, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 70, "location-fragments" : [ { "start" : 2, "end" : 70, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-25, "familyName" : "SI:CABZ01054396.2-RELATED", "score" : 93.2, "model-ac" : "PTHR24409:SF372" } ], "xref" : [ { "name" : "XP_018910212.1 PREDICTED: gastrula zinc finger protein XlCGF71.1-like [Bemisia tabaci]", "id" : "XP_018910212.1" } ] },{ "sequence" : "MRLSVCVSGICYISFLIVFVIAGSQSGLNSKQPLELIKQGSMKAGTLARKFSRVASGVLRMNPEYPTFKELDAKLRKYSSAADKEAALQDVISTGSLLYYKEKNKSTPTQTGDLEYLSDDLISLVRGSHSEFTTPETSKRKAIRGRSSCNKHCFGIYGDIYRSTHEMDPQAPPFVEGVLIPITRGWDLPRAGSGRWDIVRRKFLTRQPLRLQCRCTISDEFRDLLTANGENPEEFERLINRSRNDALQFVEQAVARINQKGVIFLLRLDHETLTQLFSVE", "md5" : "6fb883bb796d58a37ca0edf33e4b90b9", "matches" : [ ], "xref" : [ { "name" : "XP_018909765.1 PREDICTED: uncharacterized protein LOC109038945 isoform X2 [Bemisia tabaci]", "id" : "XP_018909765.1" } ] },{ "sequence" : "MNFPRRDPGIQNVSSPKKSTPSWQRLNSKQPLELIKQGSMKAGTLARKFSRVASGVLRMNPEYPTFKELDAKLRKYSSAADKEAALQDVISTGSLLYYKEKNKSTPTQTGDLEYLSDDLISLVRGSHSEFTTPETSKRKAIRGRSSCNKHCFGIYGDIYRSTHEMDPQAPPFVEGVLIPITRGWDLPRAGSGRWDIVRRKFLTRQPLRLQCRCTISDEFRDLLTANGENPEEFERLINRSRNDALQFVEQAVARINQKGVIFLLRLDHETLTQLFSVE", "md5" : "b8b249a36935db4853b0638653da3598", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 31, "location-fragments" : [ { "start" : 7, "end" : 31, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 31, "location-fragments" : [ { "start" : 1, "end" : 31, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909766.1 PREDICTED: uncharacterized protein LOC109038945 isoform X3 [Bemisia tabaci]", "id" : "XP_018909766.1" } ] },{ "sequence" : "MNVRNRGSDCQGICRGAAARRMLLLMVLGAFLVFTQYHLSVRWVAQPQQAMTLDPDSGSLDNFLRASVARIQFDDNLISIIGEKMVKEMALQLGRQIVLSNEIRGCMETDPNLPMLYIITPTYRRPEQIAELTRLAQTLMHVKNIHWLVIEDATQKTWQVTQLLERTGIKFEHLIAPMPEDLKKKKGLKPRGVSNREKGINWVRNHTTDGVLYFADDDNTYDIQIFHEMRFTKKVSMWPVGLCTGYGVSSPIVKNGVFQGFYDGWVAGRKFPVDMAGFAVNIKFLLQRPAAKMPYKPGFEEDGFLQSLAPFEPKEIELRADNCTKIYVWHTQTKKNSPAGPLDAKYNSTNLLHLKRFIV", "md5" : "f1c6bf9396cf564e80ac22e7b3191577", "matches" : [ { "signature" : { "accession" : "PF03360", "name" : "Glyco_transf_43", "description" : "Glycosyltransferase family 43", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005027", "name" : "Glyco_trans_43", "description" : "Glycosyl transferase, family 43", "type" : "FAMILY", "goXRefs" : [ { "name" : "galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0015018" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ { "name" : "A tetrasaccharide linker sequence is required for GAG synthesis", "databaseName" : "Reactome", "id" : "R-HSA-1971475" } ] } }, "locations" : [ { "start" : 135, "end" : 333, "hmmStart" : 1, "hmmEnd" : 213, "hmmLength" : 214, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.6E-63, "score" : 214.3, "envelopeStart" : 135, "envelopeEnd" : 334, "postProcessed" : true, "location-fragments" : [ { "start" : 135, "end" : 333, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-63, "score" : 214.6, "model-ac" : "PF03360" }, { "signature" : { "accession" : "PTHR10896", "name" : "GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR005027", "name" : "Glyco_trans_43", "description" : "Glycosyl transferase, family 43", "type" : "FAMILY", "goXRefs" : [ { "name" : "galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0015018" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ { "name" : "A tetrasaccharide linker sequence is required for GAG synthesis", "databaseName" : "Reactome", "id" : "R-HSA-1971475" } ] } }, "locations" : [ { "start" : 107, "end" : 359, "hmmStart" : 61, "hmmEnd" : 314, "hmmLength" : 314, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 23, "envelopeEnd" : 359, "location-fragments" : [ { "start" : 107, "end" : 359, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-129, "familyName" : "GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE P", "score" : 432.9, "model-ac" : "PTHR10896" }, { "signature" : { "accession" : "SSF53448", "name" : "Nucleotide-diphospho-sugar transferases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029044", "name" : "Nucleotide-diphossugar_trans", "description" : "Nucleotide-diphospho-sugar transferases", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 114, "end" : 337, "hmmLength" : 261, "location-fragments" : [ { "start" : 114, "end" : 337, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.81E-82, "model-ac" : "0037570" }, { "signature" : { "accession" : "G3DSA:3.90.550.10", "name" : "Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029044", "name" : "Nucleotide-diphossugar_trans", "description" : "Nucleotide-diphospho-sugar transferases", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 115, "end" : 350, "hmmStart" : 3, "hmmEnd" : 241, "hmmLength" : 261, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-91, "score" : 308.3, "envelopeStart" : 115, "envelopeEnd" : 350, "postProcessed" : true, "location-fragments" : [ { "start" : 115, "end" : 350, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-91, "score" : 308.7, "model-ac" : "3cu0A00" }, { "signature" : { "accession" : "cd00218", "name" : "GlcAT-I", "description" : "GlcAT-I", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR005027", "name" : "Glyco_trans_43", "description" : "Glycosyl transferase, family 43", "type" : "FAMILY", "goXRefs" : [ { "name" : "galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0015018" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ { "name" : "A tetrasaccharide linker sequence is required for GAG synthesis", "databaseName" : "Reactome", "id" : "R-HSA-1971475" } ] } }, "locations" : [ { "start" : 114, "end" : 335, "sites" : [ { "description" : "active site", "numLocations" : 12, "siteLocations" : [ { "start" : 265, "end" : 265, "residue" : "W" }, { "start" : 249, "end" : 249, "residue" : "S" }, { "start" : 330, "end" : 330, "residue" : "H" }, { "start" : 217, "end" : 217, "residue" : "D" }, { "start" : 219, "end" : 219, "residue" : "N" }, { "start" : 218, "end" : 218, "residue" : "D" }, { "start" : 274, "end" : 274, "residue" : "D" }, { "start" : 301, "end" : 301, "residue" : "E" }, { "start" : 123, "end" : 123, "residue" : "Y" }, { "start" : 152, "end" : 152, "residue" : "D" }, { "start" : 216, "end" : 216, "residue" : "D" }, { "start" : 269, "end" : 269, "residue" : "R" } ] }, { "description" : "putative dimerization interface", "numLocations" : 25, "siteLocations" : [ { "start" : 329, "end" : 329, "residue" : "W" }, { "start" : 220, "end" : 220, "residue" : "T" }, { "start" : 141, "end" : 141, "residue" : "H" }, { "start" : 129, "end" : 129, "residue" : "I" }, { "start" : 133, "end" : 133, "residue" : "T" }, { "start" : 140, "end" : 140, "residue" : "M" }, { "start" : 242, "end" : 242, "residue" : "L" }, { "start" : 126, "end" : 126, "residue" : "P" }, { "start" : 264, "end" : 264, "residue" : "G" }, { "start" : 262, "end" : 262, "residue" : "Y" }, { "start" : 131, "end" : 131, "residue" : "E" }, { "start" : 248, "end" : 248, "residue" : "V" }, { "start" : 130, "end" : 130, "residue" : "A" }, { "start" : 222, "end" : 222, "residue" : "D" }, { "start" : 331, "end" : 331, "residue" : "T" }, { "start" : 134, "end" : 134, "residue" : "R" }, { "start" : 137, "end" : 137, "residue" : "Q" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 138, "end" : 138, "residue" : "T" }, { "start" : 326, "end" : 326, "residue" : "I" }, { "start" : 224, "end" : 224, "residue" : "Q" }, { "start" : 223, "end" : 223, "residue" : "I" }, { "start" : 127, "end" : 127, "residue" : "E" }, { "start" : 334, "end" : 334, "residue" : "K" }, { "start" : 333, "end" : 333, "residue" : "T" } ] }, { "description" : "DXD motif", "numLocations" : 3, "siteLocations" : [ { "start" : 217, "end" : 217, "residue" : "D" }, { "start" : 218, "end" : 218, "residue" : "D" }, { "start" : 216, "end" : 216, "residue" : "D" } ] } ], "evalue" : 4.49282E-113, "score" : 326.175, "location-fragments" : [ { "start" : 114, "end" : 335, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00218" }, { "signature" : { "accession" : "PTHR10896:SF50", "name" : "GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 107, "end" : 359, "hmmStart" : 61, "hmmEnd" : 314, "hmmLength" : 314, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 23, "envelopeEnd" : 359, "location-fragments" : [ { "start" : 107, "end" : 359, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-129, "familyName" : "GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE P", "score" : 432.9, "model-ac" : "PTHR10896:SF50" } ], "xref" : [ { "name" : "XP_018910081.1 PREDICTED: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase P-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910081.1" } ] },{ "sequence" : "MAFQVYCQILRRSVMTPSALSKLSVPVTCSAIVFAASESEKKDSKTLIKPSELPFYDPVKEVKSSEPQKNDEEPSVVLEYIGIARREVWKLKESFSELTGEAYSTVGDVRKQVDEGIDYLRKEEHFPEQIAFITVGGITGLLLAFRKGFFKKLLYMASFAAGSAAIVYPDQASFYWETGKEHSGRTGTILYEFLNGLTRDYAGFDLPTLSDFSFSPMKNDSETAKDPPAKQ", "md5" : "bb19222ef3190534057716c7547700b6", "matches" : [ { "signature" : { "accession" : "PF09769", "name" : "ApoO", "description" : "Apolipoprotein O", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR019166", "name" : "MIC26/MIC27", "description" : "MICOS complex subunit MIC26/MIC27", "type" : "FAMILY", "goXRefs" : [ { "name" : "MICOS complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0061617" }, { "name" : "cristae formation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0042407" } ], "pathwayXRefs" : [ { "name" : "Cristae formation", "databaseName" : "Reactome", "id" : "R-HSA-8949613" } ] } }, "locations" : [ { "start" : 68, "end" : 173, "hmmStart" : 9, "hmmEnd" : 113, "hmmLength" : 130, "hmmBounds" : "INCOMPLETE", "evalue" : 1.1E-14, "score" : 54.5, "envelopeStart" : 58, "envelopeEnd" : 186, "postProcessed" : true, "location-fragments" : [ { "start" : 68, "end" : 173, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-15, "score" : 55.1, "model-ac" : "PF09769" }, { "signature" : { "accession" : "PTHR14564", "name" : "MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR033182", "name" : "MIC26/MIC27_animal", "description" : "MICOS complex subunit MIC26/MIC27, animal", "type" : "FAMILY", "goXRefs" : [ { "name" : "MICOS complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0061617" }, { "name" : "cristae formation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0042407" } ], "pathwayXRefs" : [ { "name" : "Cristae formation", "databaseName" : "Reactome", "id" : "R-HSA-8949613" } ] } }, "locations" : [ { "start" : 18, "end" : 198, "hmmStart" : 8, "hmmEnd" : 182, "hmmLength" : 313, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 9, "envelopeEnd" : 230, "location-fragments" : [ { "start" : 18, "end" : 198, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.2E-33, "familyName" : "MICOS COMPLEX SUBUNIT", "score" : 116.8, "model-ac" : "PTHR14564" }, { "signature" : { "accession" : "PTHR14564:SF4", "name" : "MICOS COMPLEX SUBUNIT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 198, "hmmStart" : 8, "hmmEnd" : 182, "hmmLength" : 313, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 9, "envelopeEnd" : 230, "location-fragments" : [ { "start" : 18, "end" : 198, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.2E-33, "familyName" : "MICOS COMPLEX SUBUNIT", "score" : 116.8, "model-ac" : "PTHR14564:SF4" } ], "xref" : [ { "name" : "XP_018910368.1 PREDICTED: uncharacterized protein LOC109039364 [Bemisia tabaci]", "id" : "XP_018910368.1" } ] },{ "sequence" : "MSILPAGMVFPGSKLTLSIILIINTVFWELVFSAGNPLFQNRKVLNVLHFDNCVGEEYPFKFVKWSFIRNRTTIIINGEEIITRNIDEPLTIFYRIEKCNDKANPDTCEYYNTWRWDNLCTMMKVLPFISTIRNLHTPPLSCPFRKGHYYVRNAKFDKFSLLQFLQTIGNNNRAMWKFRMEIYEKDQIVCCLDFSIQVVNFRTKNSRGNTSSSHTQTIRKADFI", "md5" : "67983b8bb2fe1f3e8630e99515aff7c3", "matches" : [ { "signature" : { "accession" : "G3DSA:2.70.220.10", "name" : "Ganglioside M2 (gm2) activator", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036846", "name" : "GM2-AP_sf", "description" : "GM2-AP, lipid-recognition domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Glycosphingolipid metabolism", "databaseName" : "Reactome", "id" : "R-HSA-1660662" }, { "name" : "Neutrophil degranulation", "databaseName" : "Reactome", "id" : "R-HSA-6798695" } ] } }, "locations" : [ { "start" : 45, "end" : 200, "hmmStart" : 6, "hmmEnd" : 161, "hmmLength" : 164, "hmmBounds" : "COMPLETE", "evalue" : 5.4E-5, "score" : 25.2, "envelopeStart" : 45, "envelopeEnd" : 200, "postProcessed" : true, "location-fragments" : [ { "start" : 45, "end" : 200, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-5, "score" : 26.4, "model-ac" : "2ag4A00" } ], "xref" : [ { "name" : "XP_018909573.1 PREDICTED: uncharacterized protein LOC109038822 [Bemisia tabaci]", "id" : "XP_018909573.1" } ] },{ "sequence" : "MAQSSIKSFFPTRKRPVVVDLKKVFDAPTSNVEHAAKRIRLSQKSPPAEDDADLKKIKKIEATPEATGTSSCVRVEQQSILEQRKEEEIILKTPEPAISNERPTTPDKAPSLEENITRDTPEPTNSSNSTNQEVGRPSTPDNSPSLEEKINEGLGLNDLKVKINRSKYYNALKDSLSRYQSRDARLKDIARRLQTNSSFEIEVPVSPVKSPLKPQKLFSSPIKTPQKGLGRRLDYTSPVKPNVYVSPRKLLEERPSPVKAVPCHLKFESLVNGDALILPFKYRSLFEIFCSVDTVSSLFHNRNEKITFSKLKAGVQEMLRRNFSESHLAQIKTVLPGAFEFSQEKYQVFGKRSEAVYHLIIRPVIKNRNGDLQEAQSSMTPTVLAARKREFSNCLLEITKRHHREFLLSLDPPLDIPTEKVTRWHAEFEVNAVPDIPQAELPVSPVQNNQLSAKDVLANAKSLLKANAKVTAAIENLSKRLEGQTEIESPRKPFPSFSVPCHSPKPTATGSAMDAVEAASKALKGVPQSLLNKIKAKQAARAVEAMTRSPAQNKKAVMLSRLPEIARVVRNLFVVERKSVLPLDQVTVKLEHSCREKLSPDEIRSHLSLIQDHAPEWLSMCLVRNANYVKLHRTADVEAVMLKLNKLVETEGRIYHCR", "md5" : "1fcd29014fd872568409edd4424039f5", "matches" : [ { "signature" : { "accession" : "SM01075", "name" : "CDT1_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR014939", "name" : "CDT1_Gemini-bd-like", "description" : "CDT1 Geminin-binding domain-like", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Activation of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68962" }, { "name" : "G1/S-Specific Transcription", "databaseName" : "Reactome", "id" : "R-HSA-69205" }, { "name" : "Assembly of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68867" }, { "name" : "Orc1 removal from chromatin", "databaseName" : "Reactome", "id" : "R-HSA-68949" }, { "name" : "CDT1 association with the CDC6:ORC:origin complex", "databaseName" : "Reactome", "id" : "R-HSA-68827" } ] } }, "locations" : [ { "start" : 278, "end" : 443, "hmmStart" : 1, "hmmEnd" : 206, "hmmLength" : 206, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-61, "score" : 220.6, "location-fragments" : [ { "start" : 278, "end" : 443, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-61, "score" : 220.6, "model-ac" : "SM01075" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 460, "end" : 480, "location-fragments" : [ { "start" : 460, "end" : 480, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "SSF46785", "name" : "\"Winged helix\" DNA-binding domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036390", "name" : "WH_DNA-bd_sf", "description" : "Winged helix DNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 275, "end" : 445, "hmmLength" : 187, "location-fragments" : [ { "start" : 275, "end" : 445, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.63E-42, "model-ac" : "0050651" }, { "signature" : { "accession" : "G3DSA:1.10.10.1420", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 517, "end" : 653, "hmmStart" : 4, "hmmEnd" : 136, "hmmLength" : 138, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-47, "score" : 162.4, "envelopeStart" : 517, "envelopeEnd" : 653, "postProcessed" : true, "location-fragments" : [ { "start" : 517, "end" : 653, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-48, "score" : 164.4, "model-ac" : "2kloA00" }, { "signature" : { "accession" : "cd08674", "name" : "Cdt1_m", "description" : "Cdt1_m", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 278, "end" : 445, "sites" : [ ], "evalue" : 5.81309E-59, "score" : 194.451, "location-fragments" : [ { "start" : 278, "end" : 445, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd08674" }, { "signature" : { "accession" : "PTHR28637", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 221, "end" : 651, "hmmStart" : 56, "hmmEnd" : 531, "hmmLength" : 534, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 170, "envelopeEnd" : 654, "location-fragments" : [ { "start" : 221, "end" : 651, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-79, "familyName" : "DNA REPLICATION FACTOR CDT1", "score" : 270.6, "model-ac" : "PTHR28637" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 117, "end" : 146, "location-fragments" : [ { "start" : 117, "end" : 146, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd08767", "name" : "Cdt1_c", "description" : "Cdt1_c", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 520, "end" : 645, "sites" : [ { "description" : "putative Cdt1-MCM complex binding site", "numLocations" : 13, "siteLocations" : [ { "start" : 624, "end" : 624, "residue" : "R" }, { "start" : 578, "end" : 578, "residue" : "K" }, { "start" : 645, "end" : 645, "residue" : "N" }, { "start" : 612, "end" : 612, "residue" : "D" }, { "start" : 577, "end" : 577, "residue" : "R" }, { "start" : 582, "end" : 582, "residue" : "P" }, { "start" : 619, "end" : 619, "residue" : "S" }, { "start" : 642, "end" : 642, "residue" : "L" }, { "start" : 604, "end" : 604, "residue" : "R" }, { "start" : 537, "end" : 537, "residue" : "K" }, { "start" : 608, "end" : 608, "residue" : "S" }, { "start" : 541, "end" : 541, "residue" : "R" }, { "start" : 621, "end" : 621, "residue" : "C" } ] } ], "evalue" : 3.17031E-42, "score" : 146.658, "location-fragments" : [ { "start" : 520, "end" : 645, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd08767" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 64, "end" : 78, "location-fragments" : [ { "start" : 64, "end" : 78, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 36, "end" : 151, "location-fragments" : [ { "start" : 36, "end" : 151, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF08839", "name" : "CDT1", "description" : "DNA replication factor CDT1 like", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR014939", "name" : "CDT1_Gemini-bd-like", "description" : "CDT1 Geminin-binding domain-like", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Activation of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68962" }, { "name" : "G1/S-Specific Transcription", "databaseName" : "Reactome", "id" : "R-HSA-69205" }, { "name" : "Assembly of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68867" }, { "name" : "Orc1 removal from chromatin", "databaseName" : "Reactome", "id" : "R-HSA-68949" }, { "name" : "CDT1 association with the CDC6:ORC:origin complex", "databaseName" : "Reactome", "id" : "R-HSA-68827" } ] } }, "locations" : [ { "start" : 278, "end" : 442, "hmmStart" : 1, "hmmEnd" : 177, "hmmLength" : 177, "hmmBounds" : "COMPLETE", "evalue" : 9.9E-52, "score" : 175.8, "envelopeStart" : 278, "envelopeEnd" : 442, "postProcessed" : true, "location-fragments" : [ { "start" : 278, "end" : 442, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-52, "score" : 175.8, "model-ac" : "PF08839" }, { "signature" : { "accession" : "PF16679", "name" : "CDT1_C", "description" : "DNA replication factor Cdt1 C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR032054", "name" : "Cdt1_C", "description" : "DNA replication factor Cdt1, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "CDT1 association with the CDC6:ORC:origin complex", "databaseName" : "Reactome", "id" : "R-HSA-68827" }, { "name" : "Orc1 removal from chromatin", "databaseName" : "Reactome", "id" : "R-HSA-68949" }, { "name" : "Assembly of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68867" }, { "name" : "Activation of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68962" }, { "name" : "G1/S-Specific Transcription", "databaseName" : "Reactome", "id" : "R-HSA-69205" } ] } }, "locations" : [ { "start" : 529, "end" : 621, "hmmStart" : 1, "hmmEnd" : 93, "hmmLength" : 96, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.0E-26, "score" : 90.7, "envelopeStart" : 529, "envelopeEnd" : 624, "postProcessed" : true, "location-fragments" : [ { "start" : 529, "end" : 621, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-26, "score" : 91.5, "model-ac" : "PF16679" }, { "signature" : { "accession" : "PTHR28637:SF1", "name" : "DNA REPLICATION FACTOR CDT1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 221, "end" : 651, "hmmStart" : 56, "hmmEnd" : 531, "hmmLength" : 534, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 170, "envelopeEnd" : 654, "location-fragments" : [ { "start" : 221, "end" : 651, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-79, "familyName" : "DNA REPLICATION FACTOR CDT1", "score" : 270.6, "model-ac" : "PTHR28637:SF1" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 37, "end" : 62, "location-fragments" : [ { "start" : 37, "end" : 62, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909691.1 PREDICTED: DNA replication factor Cdt1 isoform X2 [Bemisia tabaci]", "id" : "XP_018909691.1" } ] },{ "sequence" : "MISVFSSSAVRYLVTQQFCKMPTTRSSASAGASGESHEAPVAPPKRRRKQIKIEYPSDDKPVVKIENGVPSGTKGSKAKGKQVGAMVKAEPGTFEIKKEIKEEYEGEIDSKGDASKSADPVKSEYWQEEEKPSKWEPPHWREVLANIREMRKNTYAPVDDMGCDKNSNDDATPEVRRFHVLISLMLSSQTKDQVTHAAVERLIEHSGCTVDSLLLMDNDTLGKLIYPVGFWRRKVQYIKQTCEILKKDYNGDIPNTIKDLCKLPGVGPKMAHLAMNCGWGIVTGIGVDTHVHRISNWLPWVQKPTKEPEQTRLALEAWLPRELWSEVNHLLVGFGQSICRPVGPHCSECLNKELCKVGRATMRGEKKKKKSD", "md5" : "9bedf478fea93fad8b064189c8bfc508", "matches" : [ { "signature" : { "accession" : "MF_03183", "name" : "Endonuclease_III_Nth", "description" : "Endonuclease III-like protein 1 [NTHL1].", "signatureLibraryRelease" : { "library" : "HAMAP", "version" : "2020_01" }, "entry" : { "accession" : "IPR030841", "name" : "NTH1", "description" : "Endonuclease III-like protein 1", "type" : "FAMILY", "goXRefs" : [ { "name" : "DNA-(apurinic or apyrimidinic site) endonuclease activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003906" }, { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" }, { "name" : "base-excision repair, AP site formation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006285" }, { "name" : "DNA repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006281" }, { "name" : "DNA N-glycosylase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0019104" } ], "pathwayXRefs" : [ { "name" : "Defective NTHL1 substrate processing", "databaseName" : "Reactome", "id" : "R-HSA-9630221" }, { "name" : "Defective NTHL1 substrate binding", "databaseName" : "Reactome", "id" : "R-HSA-9630222" }, { "name" : "Cleavage of the damaged pyrimidine", "databaseName" : "Reactome", "id" : "R-HSA-110329" }, { "name" : "Recognition and association of DNA glycosylase with site containing an affected pyrimidine", "databaseName" : "Reactome", "id" : "R-HSA-110328" }, { "name" : "Displacement of DNA glycosylase by APEX1", "databaseName" : "Reactome", "id" : "R-HSA-110357" } ] } }, "locations" : [ { "start" : 136, "end" : 361, "score" : 44.515, "alignment" : "EPPHWREVLANIREMRKNTYAPVDDMGCDKNSND---DATPEVRRFHVLISLMLSSQTKDQVTHAAVERLIEH--SGCTVDSLLLMDNDTLGKLIYPVGFWRRKVQYIKQTCEILKKDYNGDIPNTIKDLCKLPGVGPKMAHLAMNCGWGIVTGIGVDTHVHRISNWLPWVQKpTKEPEQTRLALEAWLPRELWSEVNHLLVGFGQSICRPVGPHCSECLNKELCKVGRAT", "location-fragments" : [ { "start" : 136, "end" : 361, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "MF_03183" }, { "signature" : { "accession" : "SM00478", "name" : "endo3end", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003265", "name" : "HhH-GPD_domain", "description" : "HhH-GPD domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "base-excision repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006284" } ], "pathwayXRefs" : [ { "name" : "Displacement of DNA glycosylase by APEX1", "databaseName" : "Reactome", "id" : "R-HSA-110357" } ] } }, "locations" : [ { "start" : 186, "end" : 337, "hmmStart" : 1, "hmmEnd" : 179, "hmmLength" : 179, "hmmBounds" : "COMPLETE", "evalue" : 7.1E-49, "score" : 178.4, "location-fragments" : [ { "start" : 186, "end" : 337, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.1E-49, "score" : 178.4, "model-ac" : "SM00478" }, { "signature" : { "accession" : "PTHR43286:SF1", "name" : "ENDONUCLEASE III-LIKE PROTEIN 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 64, "end" : 369, "hmmStart" : 54, "hmmEnd" : 323, "hmmLength" : 338, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 372, "location-fragments" : [ { "start" : 64, "end" : 369, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-121, "familyName" : "ENDONUCLEASE III-LIKE PROTEIN 1", "score" : 406.4, "model-ac" : "PTHR43286:SF1" }, { "signature" : { "accession" : "PTHR43286", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 64, "end" : 369, "hmmStart" : 54, "hmmEnd" : 323, "hmmLength" : 338, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 372, "location-fragments" : [ { "start" : 64, "end" : 369, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-121, "familyName" : "ENDONUCLEASE III-LIKE PROTEIN 1", "score" : 406.4, "model-ac" : "PTHR43286" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 78, "location-fragments" : [ { "start" : 25, "end" : 78, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00633", "name" : "HHH", "description" : "Helix-hairpin-helix motif", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000445", "name" : "HhH_motif", "description" : "Helix-hairpin-helix motif", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ { "name" : "Displacement of DNA glycosylase by APEX1", "databaseName" : "Reactome", "id" : "R-HSA-110357" } ] } }, "locations" : [ { "start" : 249, "end" : 272, "hmmStart" : 2, "hmmEnd" : 25, "hmmLength" : 30, "hmmBounds" : "INCOMPLETE", "evalue" : 2.4E-8, "score" : 33.4, "envelopeStart" : 248, "envelopeEnd" : 276, "postProcessed" : true, "location-fragments" : [ { "start" : 249, "end" : 272, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-8, "score" : 34.5, "model-ac" : "PF00633" }, { "signature" : { "accession" : "G3DSA:1.10.1670.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR023170", "name" : "HTH_base_excis_C", "description" : "Helix-turn-helix, base-excision DNA repair, C-terminal", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Displacement of DNA glycosylase by APEX1", "databaseName" : "Reactome", "id" : "R-HSA-110357" } ] } }, "locations" : [ { "start" : 281, "end" : 361, "hmmStart" : 21, "hmmEnd" : 93, "hmmLength" : 99, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.7E-23, "score" : 83.0, "envelopeStart" : 280, "envelopeEnd" : 361, "postProcessed" : true, "location-fragments" : [ { "start" : 281, "end" : 361, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-23, "score" : 84.3, "model-ac" : "2abkA02" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 40, "end" : 61, "location-fragments" : [ { "start" : 40, "end" : 61, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00056", "name" : "ENDO3c", "description" : "ENDO3c", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR003265", "name" : "HhH-GPD_domain", "description" : "HhH-GPD domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "base-excision repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006284" } ], "pathwayXRefs" : [ { "name" : "Displacement of DNA glycosylase by APEX1", "databaseName" : "Reactome", "id" : "R-HSA-110357" } ] } }, "locations" : [ { "start" : 178, "end" : 335, "sites" : [ { "description" : "active site", "numLocations" : 1, "siteLocations" : [ { "start" : 288, "end" : 288, "residue" : "D" } ] }, { "description" : "helix-hairpin-helix signature motif", "numLocations" : 8, "siteLocations" : [ { "start" : 263, "end" : 263, "residue" : "L" }, { "start" : 264, "end" : 264, "residue" : "P" }, { "start" : 265, "end" : 265, "residue" : "G" }, { "start" : 269, "end" : 269, "residue" : "K" }, { "start" : 270, "end" : 270, "residue" : "M" }, { "start" : 266, "end" : 266, "residue" : "V" }, { "start" : 268, "end" : 268, "residue" : "P" }, { "start" : 267, "end" : 267, "residue" : "G" } ] }, { "description" : "substrate binding pocket", "numLocations" : 3, "siteLocations" : [ { "start" : 328, "end" : 328, "residue" : "N" }, { "start" : 332, "end" : 332, "residue" : "V" }, { "start" : 273, "end" : 273, "residue" : "L" } ] }, { "description" : "minor groove reading motif", "numLocations" : 5, "siteLocations" : [ { "start" : 234, "end" : 234, "residue" : "K" }, { "start" : 190, "end" : 190, "residue" : "T" }, { "start" : 191, "end" : 191, "residue" : "K" }, { "start" : 194, "end" : 194, "residue" : "V" }, { "start" : 189, "end" : 189, "residue" : "Q" } ] } ], "evalue" : 2.27572E-46, "score" : 153.937, "location-fragments" : [ { "start" : 178, "end" : 335, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00056" }, { "signature" : { "accession" : "G3DSA:1.10.340.30", "name" : "Hypothetical protein; domain 2", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 170, "end" : 280, "hmmStart" : 9, "hmmEnd" : 111, "hmmLength" : 112, "hmmBounds" : "COMPLETE", "evalue" : 5.3E-31, "score" : 109.3, "envelopeStart" : 170, "envelopeEnd" : 280, "postProcessed" : true, "location-fragments" : [ { "start" : 170, "end" : 280, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-31, "score" : 110.3, "model-ac" : "1kg2A02" }, { "signature" : { "accession" : "PF00730", "name" : "HhH-GPD", "description" : "HhH-GPD superfamily base excision DNA repair protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR003265", "name" : "HhH-GPD_domain", "description" : "HhH-GPD domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "base-excision repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006284" } ], "pathwayXRefs" : [ { "name" : "Displacement of DNA glycosylase by APEX1", "databaseName" : "Reactome", "id" : "R-HSA-110357" } ] } }, "locations" : [ { "start" : 182, "end" : 319, "hmmStart" : 1, "hmmEnd" : 106, "hmmLength" : 108, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.9E-19, "score" : 70.3, "envelopeStart" : 182, "envelopeEnd" : 321, "postProcessed" : true, "location-fragments" : [ { "start" : 273, "end" : 319, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 182, "end" : 248, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.7E-19, "score" : 70.3, "model-ac" : "PF00730" }, { "signature" : { "accession" : "SSF48150", "name" : "DNA-glycosylase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011257", "name" : "DNA_glycosylase", "description" : "DNA glycosylase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" }, { "name" : "DNA repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006281" } ], "pathwayXRefs" : [ { "name" : "Displacement of DNA glycosylase by APEX1", "databaseName" : "Reactome", "id" : "R-HSA-110357" } ] } }, "locations" : [ { "start" : 147, "end" : 361, "hmmLength" : 221, "location-fragments" : [ { "start" : 147, "end" : 361, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.28E-58, "model-ac" : "0043362" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 105, "end" : 130, "location-fragments" : [ { "start" : 105, "end" : 130, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS01155", "name" : "ENDONUCLEASE_III_2", "description" : "Endonuclease III family signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR004036", "name" : "Endonuclease-III-like_CS2", "description" : "Endonuclease III-like, conserved site-2", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Displacement of DNA glycosylase by APEX1", "databaseName" : "Reactome", "id" : "R-HSA-110357" } ] } }, "locations" : [ { "start" : 251, "end" : 280, "level" : "STRONG", "cigarAlignment" : "1M1I2M5I1M2I5M3I1M3I1M2I3M", "alignment" : "GdIPntikdLckLPGVGpkmAhlaMncGWG", "location-fragments" : [ { "start" : 251, "end" : 280, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01155" } ], "xref" : [ { "name" : "XP_018910276.1 PREDICTED: endonuclease III-like protein 1 [Bemisia tabaci]", "id" : "XP_018910276.1" } ] },{ "sequence" : "MKLLLQHMVLSAILLVGNTVSEMDEEFDDEQLDDDILTELYKFGDRLFREPDKKAGERLQQWDASSRVNPEEVGTYAEGDILHPRQDGRNGLRAVTSRWPNGVIPYEINPYFRQTDRAMIQSAMSDYERLTCLKWVPRSSYDTDYVYFTNGNTGCWSSVGRIGGRQEVNLQSPGCLTTRGTVMHEMMHAAGFMHEQNRPERDKFVLIRYENIETGRENNFDKASTSAVDSLGVGYDYQSVMHYSANAFSRNGQPTIQSRTPGVQMGQREGLSDRDIKKIRKMYGCDDNSGGGGGGGGGGGGSGGSGGGNGGPKPTKKPKKKKPKKKKPHSEEVL", "md5" : "a3edf31ab3e7d4f32980a2406cf62966", "matches" : [ { "signature" : { "accession" : "PTHR10127", "name" : "DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 307, "hmmStart" : 21, "hmmEnd" : 314, "hmmLength" : 339, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 322, "location-fragments" : [ { "start" : 18, "end" : 307, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-111, "familyName" : "METALLOENDOPEPTIDASE", "score" : 373.1, "model-ac" : "PTHR10127" }, { "signature" : { "accession" : "SSF55486", "name" : "Metalloproteases (\"zincins\"), catalytic domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 96, "end" : 286, "hmmLength" : 200, "location-fragments" : [ { "start" : 96, "end" : 286, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-56, "model-ac" : "0047333" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 251, "end" : 334, "location-fragments" : [ { "start" : 251, "end" : 334, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR10127:SF837", "name" : "METALLOENDOPEPTIDASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 307, "hmmStart" : 21, "hmmEnd" : 314, "hmmLength" : 339, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 322, "location-fragments" : [ { "start" : 18, "end" : 307, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-111, "familyName" : "METALLOENDOPEPTIDASE", "score" : 373.1, "model-ac" : "PTHR10127:SF837" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 251, "end" : 265, "location-fragments" : [ { "start" : 251, "end" : 265, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF01400", "name" : "Astacin", "description" : "Astacin (Peptidase family M12A)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001506", "name" : "Peptidase_M12A", "description" : "Peptidase M12A", "type" : "DOMAIN", "goXRefs" : [ { "name" : "metalloendopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004222" }, { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 98, "end" : 286, "hmmStart" : 2, "hmmEnd" : 190, "hmmLength" : 191, "hmmBounds" : "INCOMPLETE", "evalue" : 2.7E-62, "score" : 209.8, "envelopeStart" : 97, "envelopeEnd" : 287, "postProcessed" : true, "location-fragments" : [ { "start" : 98, "end" : 286, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-62, "score" : 210.1, "model-ac" : "PF01400" }, { "signature" : { "accession" : "cd04280", "name" : "ZnMc_astacin_like", "description" : "ZnMc_astacin_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR034035", "name" : "Astacin-like_dom", "description" : "Astacin-like metallopeptidase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "metalloendopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004222" }, { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 101, "end" : 283, "sites" : [ { "description" : "active site", "numLocations" : 5, "siteLocations" : [ { "start" : 188, "end" : 188, "residue" : "H" }, { "start" : 185, "end" : 185, "residue" : "E" }, { "start" : 194, "end" : 194, "residue" : "H" }, { "start" : 184, "end" : 184, "residue" : "H" }, { "start" : 243, "end" : 243, "residue" : "Y" } ] } ], "evalue" : 2.11359E-92, "score" : 270.982, "location-fragments" : [ { "start" : 101, "end" : 283, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd04280" }, { "signature" : { "accession" : "G3DSA:3.40.390.10", "name" : "Collagenase (Catalytic Domain)", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR024079", "name" : "MetalloPept_cat_dom_sf", "description" : "Metallopeptidase, catalytic domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "metallopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008237" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 55, "end" : 288, "hmmStart" : 16, "hmmEnd" : 234, "hmmLength" : 237, "hmmBounds" : "COMPLETE", "evalue" : 3.4E-79, "score" : 267.6, "envelopeStart" : 55, "envelopeEnd" : 288, "postProcessed" : true, "location-fragments" : [ { "start" : 55, "end" : 288, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-79, "score" : 268.1, "model-ac" : "4gwmA01" }, { "signature" : { "accession" : "SM00235", "name" : "col_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006026", "name" : "Peptidase_Metallo", "description" : "Peptidase, metallopeptidase", "type" : "DOMAIN", "goXRefs" : [ { "name" : "metallopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008237" }, { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 95, "end" : 239, "hmmStart" : 1, "hmmEnd" : 204, "hmmLength" : 204, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-46, "score" : 170.0, "location-fragments" : [ { "start" : 95, "end" : 239, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-46, "score" : 170.0, "model-ac" : "SM00235" }, { "signature" : { "accession" : "PR00480", "name" : "ASTACIN", "description" : "Astacin family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001506", "name" : "Peptidase_M12A", "description" : "Peptidase M12A", "type" : "DOMAIN", "goXRefs" : [ { "name" : "metalloendopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004222" }, { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 120, "end" : 138, "pvalue" : 6.67E-6, "score" : 32.37, "motifNumber" : 1, "location-fragments" : [ { "start" : 120, "end" : 138, "dc-status" : "CONTINUOUS" } ] }, { "start" : 271, "end" : 284, "pvalue" : 1.43E-4, "score" : 38.1, "motifNumber" : 5, "location-fragments" : [ { "start" : 271, "end" : 284, "dc-status" : "CONTINUOUS" } ] }, { "start" : 234, "end" : 249, "pvalue" : 2.69E-8, "score" : 55.62, "motifNumber" : 4, "location-fragments" : [ { "start" : 234, "end" : 249, "dc-status" : "CONTINUOUS" } ] }, { "start" : 195, "end" : 212, "pvalue" : 1.16E-7, "score" : 46.02, "motifNumber" : 3, "location-fragments" : [ { "start" : 195, "end" : 212, "dc-status" : "CONTINUOUS" } ] }, { "start" : 176, "end" : 194, "pvalue" : 4.34E-7, "score" : 43.51, "motifNumber" : 2, "location-fragments" : [ { "start" : 176, "end" : 194, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-24, "graphscan" : "IIIII", "model-ac" : "PR00480" }, { "signature" : { "accession" : "PS51864", "name" : "ASTACIN", "description" : "Astacin-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 93, "end" : 286, "score" : 76.643, "alignment" : "RAVTS---RWPNGVIPYEINPYFRQTDRAMIQSAMSDYERLTCLKWVPRSSYdTDYVYFTNgNTGCW--SSVGRI-GGRQEVNLQSpGCLTTrGTVMHEMMHAAGFMHEQNRPERDKFVLIRYENIETGRENNFDKASTSAVDSLGVGYDYQSVMHYSANAFSRNG-QPTIQSR------TpgvqMGQREGLSDRDIKKIRKMYGCD", "location-fragments" : [ { "start" : 93, "end" : 286, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51864" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 270, "end" : 284, "location-fragments" : [ { "start" : 270, "end" : 284, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910288.1 PREDICTED: zinc metalloproteinase nas-13-like [Bemisia tabaci]", "id" : "XP_018910288.1" } ] },{ "sequence" : "MADSNNKINFCTSSPGKIILFGEHSVVYGKLAVAASISNRTTATFKEVEGDVFTLNLPKLGYCETFELANLQSKLDENIPLKKKISKQQTDLGTVGLVDIDALLELSGKDVNFNASVEQSDAIRKALHAFFFLFRGILGTTLVNVPPSTLEIDSELELGAGTGSSASFCVTLAAAFIQLLKQRTPPGYRVSKHEYRNFTFDGSLESFSEKEKIIISCWALHGEKINHGKPSGLDNSVCTHGAILQMNVRGFLKHEGGFQCMDLNIKLSVLLINSGVSRDTKSLVSKVRSLKARHEGVINLILNSMEGIAEKGVLTLQKLSDLEKAKASDKDIRSLYTVLEELFDLNHGLLSTLQVSHEKLEHIRAITAGFGLHTKLTGAGGGGYAIALIPPDYPVNVLPECINQLEANNYQTRQIYLGGEGVNVKQLS", "md5" : "4905ffe66cf0e1710c7c0345d88c803d", "matches" : [ { "signature" : { "accession" : "PTHR43290:SF2", "name" : "MEVALONATE KINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 424, "hmmStart" : 6, "hmmEnd" : 379, "hmmLength" : 380, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 425, "location-fragments" : [ { "start" : 11, "end" : 424, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-90, "familyName" : "MEVALONATE KINASE", "score" : 305.7, "model-ac" : "PTHR43290:SF2" }, { "signature" : { "accession" : "SSF55060", "name" : "GHMP Kinase, C-terminal domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036554", "name" : "GHMP_kinase_C_sf", "description" : "GHMP kinase, C-terminal domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 265, "end" : 424, "hmmLength" : 169, "location-fragments" : [ { "start" : 265, "end" : 424, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.48E-30, "model-ac" : "0047892" }, { "signature" : { "accession" : "G3DSA:3.30.70.890", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036554", "name" : "GHMP_kinase_C_sf", "description" : "GHMP kinase, C-terminal domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 264, "end" : 419, "hmmStart" : 2, "hmmEnd" : 366, "hmmLength" : 148, "hmmBounds" : "INCOMPLETE", "evalue" : 1.4E-113, "score" : 381.8, "envelopeStart" : 12, "envelopeEnd" : 423, "postProcessed" : true, "location-fragments" : [ { "start" : 264, "end" : 419, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-113, "score" : 382.0, "model-ac" : "2r3vA02" }, { "signature" : { "accession" : "PF00288", "name" : "GHMP_kinases_N", "description" : "GHMP kinases N terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006204", "name" : "GHMP_kinase_N_dom", "description" : "GHMP kinase N-terminal domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 150, "end" : 241, "hmmStart" : 2, "hmmEnd" : 65, "hmmLength" : 66, "hmmBounds" : "INCOMPLETE", "evalue" : 1.3E-10, "score" : 41.4, "envelopeStart" : 149, "envelopeEnd" : 242, "postProcessed" : true, "location-fragments" : [ { "start" : 150, "end" : 241, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-11, "score" : 42.9, "model-ac" : "PF00288" }, { "signature" : { "accession" : "PR00959", "name" : "MEVGALKINASE", "description" : "Mevalonate kinase family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : null }, "locations" : [ { "start" : 154, "end" : 176, "pvalue" : 6.21E-8, "score" : 37.98, "motifNumber" : 2, "location-fragments" : [ { "start" : 154, "end" : 176, "dc-status" : "CONTINUOUS" } ] }, { "start" : 14, "end" : 38, "pvalue" : 8.37E-10, "score" : 39.29, "motifNumber" : 1, "location-fragments" : [ { "start" : 14, "end" : 38, "dc-status" : "CONTINUOUS" } ] }, { "start" : 373, "end" : 390, "pvalue" : 4.4E-9, "score" : 49.51, "motifNumber" : 4, "location-fragments" : [ { "start" : 373, "end" : 390, "dc-status" : "CONTINUOUS" } ] }, { "start" : 223, "end" : 242, "pvalue" : 0.0175, "score" : 25.59, "motifNumber" : 3, "location-fragments" : [ { "start" : 223, "end" : 242, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-21, "graphscan" : "IIiI", "model-ac" : "PR00959" }, { "signature" : { "accession" : "PTHR43290", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 424, "hmmStart" : 6, "hmmEnd" : 379, "hmmLength" : 380, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 425, "location-fragments" : [ { "start" : 11, "end" : 424, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-90, "familyName" : "MEVALONATE KINASE", "score" : 305.7, "model-ac" : "PTHR43290" }, { "signature" : { "accession" : "TIGR00549", "name" : "TIGR00549", "description" : "mevalon_kin: mevalonate kinase", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR006205", "name" : "Mev_gal_kin", "description" : "Mevalonate kinase", "type" : "FAMILY", "goXRefs" : [ { "name" : "isoprenoid biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0008299" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "cytoplasm", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005737" }, { "name" : "mevalonate kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004496" } ], "pathwayXRefs" : [ { "name" : "Cholesterol biosynthesis", "databaseName" : "Reactome", "id" : "R-HSA-191273" }, { "name" : "Mevalonate pathway I", "databaseName" : "MetaCyc", "id" : "PWY-922" }, { "name" : "Isoprene biosynthesis II (engineered)", "databaseName" : "MetaCyc", "id" : "PWY-7391" }, { "name" : "Mevalonate pathway II (archaea)", "databaseName" : "MetaCyc", "id" : "PWY-6174" }, { "name" : "Terpenoid backbone biosynthesis", "databaseName" : "KEGG", "id" : "00900+2.7.1.36" }, { "name" : "Activation of gene expression by SREBF (SREBP)", "databaseName" : "Reactome", "id" : "R-HSA-2426168" } ] } }, "locations" : [ { "start" : 14, "end" : 388, "hmmStart" : 1, "hmmEnd" : 276, "hmmLength" : 276, "hmmBounds" : "COMPLETE", "evalue" : 9.6E-60, "score" : 200.3, "envelopeStart" : 14, "envelopeEnd" : 388, "postProcessed" : false, "location-fragments" : [ { "start" : 14, "end" : 388, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-60, "score" : 200.8, "model-ac" : "TIGR00549" }, { "signature" : { "accession" : "SSF54211", "name" : "Ribosomal protein S5 domain 2-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR020568", "name" : "Ribosomal_S5_D2-typ_fold", "description" : "Ribosomal protein S5 domain 2-type fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 250, "hmmLength" : 225, "location-fragments" : [ { "start" : 120, "end" : 250, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 10, "end" : 83, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.13E-26, "model-ac" : "0040285" }, { "signature" : { "accession" : "G3DSA:3.30.230.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR014721", "name" : "Ribosomal_S5_D2-typ_fold_subgr", "description" : "Ribosomal protein S5 domain 2-type fold, subgroup", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 422, "hmmStart" : 2, "hmmEnd" : 366, "hmmLength" : 367, "hmmBounds" : "INCOMPLETE", "evalue" : 1.4E-113, "score" : 381.8, "envelopeStart" : 12, "envelopeEnd" : 423, "postProcessed" : true, "location-fragments" : [ { "start" : 420, "end" : 422, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 13, "end" : 263, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.2E-113, "score" : 382.0, "model-ac" : "2r3vA01" } ], "xref" : [ { "name" : "XP_018909958.1 PREDICTED: mevalonate kinase [Bemisia tabaci]", "id" : "XP_018909958.1" } ] },{ "sequence" : "MQDLFNSATTQMACKIVLLGIIGVAASTTHRKVMIRMPKQMKNTEMKEAMSNDPQMPTMSQPKDQSPEQSRVAVGNEDTGKGKGEYFMDVYSLETGPEQLEFGHVLEDPNEWEQRYERKDHENNRFQGKVRWGDKRGSYGEHYWDFNHGGHDKEQPGMASESQKEPQMMKMSETKRSHDYAMPQPSTKNHRMNQRAATVKPDVNERVKRHKKIQLPKLVFDTETWTVIDENTDQHFFLQPIVNP", "md5" : "3eeb384213bf6af6ae62007ffb35af14", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 46, "end" : 73, "location-fragments" : [ { "start" : 46, "end" : 73, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 46, "end" : 79, "location-fragments" : [ { "start" : 46, "end" : 79, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910452.1 PREDICTED: uncharacterized protein LOC109039434 isoform X1 [Bemisia tabaci]", "id" : "XP_018910452.1" } ] },{ "sequence" : "MAKDNVMAKDSGLAKETCDQVFEKISKNDIEGLRTLLADLRDKPDFHDEHGMSPLQHAAYKGNKQICQMLIDQGADVNAGKYEQGYTALHFAALSGNSELCAILLAAGAKSHATNSIGRTASQMAAFVGNHDCVAVINNFMPKSEVEYLTVPHGLETEPQLPPLLATPLHNLIMQVNVHPIRVALNLHKVLLDNLDVTKKALHTLCEKEMKKGQGSSEVLAFKLHYLACVVGEVAKHRQADKQNDVVTAFAKTCLNPSRGEEYVEQFIRDCVREFPFRDCTIFKQMLTTLAKRDTSPPGVVVISNAINGQRGFSDGSSQCVTCGQEKVIRKCSKCRAVQYCDRECQRLHWFVHKKECNRETTNSNQNGVK", "md5" : "1c27616b177f14f7a1441547f0ae5932", "matches" : [ { "signature" : { "accession" : "SSF144232", "name" : "HIT/MYND zinc finger-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 318, "end" : 359, "hmmLength" : 57, "location-fragments" : [ { "start" : 318, "end" : 359, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.22E-11, "model-ac" : "0052402" }, { "signature" : { "accession" : "PTHR24150", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 365, "hmmStart" : 23, "hmmEnd" : 382, "hmmLength" : 419, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 370, "location-fragments" : [ { "start" : 16, "end" : 365, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-110, "familyName" : "ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2", "score" : 371.8, "model-ac" : "PTHR24150" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 84, "end" : 116, "score" : 12.235, "alignment" : "QGYTALHFAALSGNSELCAILLAAGAKSHATNS", "location-fragments" : [ { "start" : 84, "end" : 116, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "SSF48403", "name" : "Ankyrin repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 26, "end" : 139, "hmmLength" : 156, "location-fragments" : [ { "start" : 26, "end" : 139, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.32E-25, "model-ac" : "0045715" }, { "signature" : { "accession" : "G3DSA:3.30.60.180", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 308, "end" : 364, "hmmStart" : 11, "hmmEnd" : 54, "hmmLength" : 60, "hmmBounds" : "COMPLETE", "evalue" : 3.8E-13, "score" : 51.0, "envelopeStart" : 308, "envelopeEnd" : 364, "postProcessed" : true, "location-fragments" : [ { "start" : 308, "end" : 364, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-13, "score" : 51.0, "model-ac" : "2od1A00" }, { "signature" : { "accession" : "PF13637", "name" : "Ank_4", "description" : "Ankyrin repeats (many copies)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 51, "end" : 104, "hmmStart" : 1, "hmmEnd" : 54, "hmmLength" : 55, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.8E-9, "score" : 36.1, "envelopeStart" : 51, "envelopeEnd" : 105, "postProcessed" : true, "location-fragments" : [ { "start" : 51, "end" : 104, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-16, "score" : 61.0, "model-ac" : "PF13637" }, { "signature" : { "accession" : "PF01753", "name" : "zf-MYND", "description" : "MYND finger", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002893", "name" : "Znf_MYND", "description" : "Zinc finger, MYND-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 320, "end" : 357, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 8.7E-10, "score" : 38.5, "envelopeStart" : 320, "envelopeEnd" : 357, "postProcessed" : true, "location-fragments" : [ { "start" : 320, "end" : 357, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-10, "score" : 39.6, "model-ac" : "PF01753" }, { "signature" : { "accession" : "SM00248", "name" : "ANK_2a", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 117, "end" : 148, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 2200.0, "score" : 2.5, "location-fragments" : [ { "start" : 117, "end" : 148, "dc-status" : "CONTINUOUS" } ] }, { "start" : 84, "end" : 113, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 0.0088, "score" : 25.2, "location-fragments" : [ { "start" : 84, "end" : 113, "dc-status" : "CONTINUOUS" } ] }, { "start" : 50, "end" : 79, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 9.5E-6, "score" : 35.1, "location-fragments" : [ { "start" : 50, "end" : 79, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-14, "score" : 62.8, "model-ac" : "SM00248" }, { "signature" : { "accession" : "PS50865", "name" : "ZF_MYND_2", "description" : "Zinc finger MYND-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002893", "name" : "Znf_MYND", "description" : "Zinc finger, MYND-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 320, "end" : 357, "score" : 12.571, "alignment" : "CVTCGQEKVIRKCSKCRAVQYCDRECQRLHWFVHKKEC", "location-fragments" : [ { "start" : 320, "end" : 357, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50865" }, { "signature" : { "accession" : "PS50297", "name" : "ANK_REP_REGION", "description" : "Ankyrin repeat region circular profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR020683", "name" : "Ankyrin_rpt-contain_dom", "description" : "Ankyrin repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 137, "score" : 24.719, "alignment" : "HGMSPLQHAAYKGNKQICQMLIDQGADVNAGKYeQGYTALHFAALSGNSELCAILLAAGAKSHATNSIGRTASQMAAFVGNHDCVAVI------------", "location-fragments" : [ { "start" : 50, "end" : 137, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50297" }, { "signature" : { "accession" : "PTHR24150:SF8", "name" : "ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 365, "hmmStart" : 23, "hmmEnd" : 382, "hmmLength" : 419, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 370, "location-fragments" : [ { "start" : 16, "end" : 365, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-110, "familyName" : "ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2", "score" : 371.8, "model-ac" : "PTHR24150:SF8" }, { "signature" : { "accession" : "PS01360", "name" : "ZF_MYND_1", "description" : "Zinc finger MYND-type signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR002893", "name" : "Znf_MYND", "description" : "Zinc finger, MYND-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 320, "end" : 357, "level" : "STRONG", "cigarAlignment" : "1M2I1M8I1M2I1M4I2M3I1M7I1M3I1M", "alignment" : "CvtCgqekvirkCskCravqYCdreCqrlhwfvHkkeC", "location-fragments" : [ { "start" : 320, "end" : 357, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01360" }, { "signature" : { "accession" : "G3DSA:1.25.40.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 144, "hmmStart" : 5, "hmmEnd" : 123, "hmmLength" : 179, "hmmBounds" : "COMPLETE", "evalue" : 5.8E-28, "score" : 99.5, "envelopeStart" : 14, "envelopeEnd" : 144, "postProcessed" : true, "location-fragments" : [ { "start" : 14, "end" : 144, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-28, "score" : 99.5, "model-ac" : "4hi8A00" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 82, "score" : 12.315, "alignment" : "HGMSPLQHAAYKGNKQICQMLIDQGADVNAGKY", "location-fragments" : [ { "start" : 50, "end" : 82, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" } ], "xref" : [ { "name" : "XP_018909769.1 PREDICTED: ankyrin repeat and MYND domain-containing protein 2 [Bemisia tabaci]", "id" : "XP_018909769.1" } ] },{ "sequence" : "MAGESTAGKPPEPPTSKEKLLFYTTGFFILLGIFSLFGFLFLVPFVIEPAFTTIFAAFDVTPAMCVTRHVERMRGVSNCSWTSCREGCTREVYECTQIRVNYKITKPSPTPPPPTATPTTPESAFDNNFLDRRRRRRRRLLSMQDYDYSDILGHELPAPDPDEETPPTTTDVADPSDSEWFFVGAKLFPNVKGCGYPPMLNCTVFLKNYSQLGTNFSCFYSTVDPGIVITQLDMLQVYRHLLYALAIPIPSFIASVVYLTLAYLYIYSEDSAPPPRPPRKRPVVEASPLAPLSLNPAASASGSASLDPPPTTGALTPASEVFRDDMASFGHQLKVAMADDFLSRDSLGSITFVNSSSLNGDDVDSFGRQLKAAMTEDFLSKESLGSLSFLNSSSVNGNLNKMMTTCILTPPGPIAEL", "md5" : "9fbdb95bd8f14cdd6362d2a442965d21", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 104, "end" : 128, "location-fragments" : [ { "start" : 104, "end" : 128, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12335", "name" : "TIPE PROTEIN TEMPERATURE-INDUCED PARALYTIC E", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR031578", "name" : "TipE", "description" : "Na+ channel auxiliary subunit TipE", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 360, "hmmStart" : 7, "hmmEnd" : 338, "hmmLength" : 358, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 363, "location-fragments" : [ { "start" : 13, "end" : 360, "dc-status" : "CONTINUOUS" } ] }, { "start" : 362, "end" : 416, "hmmStart" : 304, "hmmEnd" : 357, "hmmLength" : 358, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 358, "envelopeEnd" : 417, "location-fragments" : [ { "start" : 362, "end" : 416, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-113, "familyName" : "PROTEIN TIPE", "score" : 380.8, "model-ac" : "PTHR12335" }, { "signature" : { "accession" : "PTHR12335:SF6", "name" : "PROTEIN TIPE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 13, "end" : 360, "hmmStart" : 7, "hmmEnd" : 338, "hmmLength" : 358, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 363, "location-fragments" : [ { "start" : 13, "end" : 360, "dc-status" : "CONTINUOUS" } ] }, { "start" : 362, "end" : 416, "hmmStart" : 304, "hmmEnd" : 357, "hmmLength" : 358, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 358, "envelopeEnd" : 417, "location-fragments" : [ { "start" : 362, "end" : 416, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-113, "familyName" : "PROTEIN TIPE", "score" : 380.8, "model-ac" : "PTHR12335:SF6" }, { "signature" : { "accession" : "PF16972", "name" : "TipE", "description" : "Na+ channel auxiliary subunit TipE", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR031578", "name" : "TipE", "description" : "Na+ channel auxiliary subunit TipE", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 361, "end" : 415, "hmmStart" : 431, "hmmEnd" : 484, "hmmLength" : 486, "hmmBounds" : "INCOMPLETE", "evalue" : 3.1E-12, "score" : 46.4, "envelopeStart" : 359, "envelopeEnd" : 417, "postProcessed" : true, "location-fragments" : [ { "start" : 361, "end" : 415, "dc-status" : "CONTINUOUS" } ] }, { "start" : 311, "end" : 361, "hmmStart" : 421, "hmmEnd" : 467, "hmmLength" : 486, "hmmBounds" : "INCOMPLETE", "evalue" : 5.7E-7, "score" : 29.1, "envelopeStart" : 286, "envelopeEnd" : 362, "postProcessed" : true, "location-fragments" : [ { "start" : 311, "end" : 361, "dc-status" : "CONTINUOUS" } ] }, { "start" : 176, "end" : 271, "hmmStart" : 227, "hmmEnd" : 322, "hmmLength" : 486, "hmmBounds" : "INCOMPLETE", "evalue" : 2.4E-46, "score" : 159.0, "envelopeStart" : 160, "envelopeEnd" : 275, "postProcessed" : true, "location-fragments" : [ { "start" : 176, "end" : 271, "dc-status" : "CONTINUOUS" } ] }, { "start" : 13, "end" : 105, "hmmStart" : 7, "hmmEnd" : 99, "hmmLength" : 486, "hmmBounds" : "INCOMPLETE", "evalue" : 1.3E-49, "score" : 169.7, "envelopeStart" : 8, "envelopeEnd" : 147, "postProcessed" : true, "location-fragments" : [ { "start" : 13, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-118, "score" : 396.1, "model-ac" : "PF16972" } ], "xref" : [ { "name" : "XP_018910399.1 PREDICTED: protein tipE [Bemisia tabaci]", "id" : "XP_018910399.1" }, { "name" : "XP_018910398.1 PREDICTED: protein tipE [Bemisia tabaci]", "id" : "XP_018910398.1" } ] },{ "sequence" : "MWKLSHKYTKNGSPGKLWIGHRLIVFLSHPKDIEVIYGSQTHIYKSPEYGFFNSWLRSGILINNGEKWRALRKLIAPSFHLNVLRSFVDHFYKHSLSVVHKMKEEGSKEFDVHHYMGACTTEILLETAMGVDKKTHQVNGFEYASAVMKLCEILHLRQVKLWLRPDSAFKLTSYASEHNRLLKYIDELPQKVTKKKRADFLKKKQTTVEKCNTKSEEVKEAERGAQRLDAKRNKGEVTETVEGVSYGQSAGLKDDLDDDIGEKKRQPFLESLIENAANGANLTDEDIRDQINTIMFAGHDTTAAGSSFFLCMMGVRPDIQEKVVEELEQIFGDSDRPCTFEDTLEMKYMERCIMETLRLYPPVPMTGREPQEEIKLKSTDLTVPAKCTIVIGIFKLHRDPSIYPNPDEFNPDNFLPEKTTNRHYYAFVPFGAGPRGCLGRKFAMLQLKVLLSTVLRNYKIYSDVPQKDWKLQADIILKRADGFRIRLEPRKMTPKPKN", "md5" : "7661fb7112c1e9f5be156fde00483629", "matches" : [ { "signature" : { "accession" : "PR00385", "name" : "P450", "description" : "P450 superfamily signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001128", "name" : "Cyt_P450", "description" : "Cytochrome P450", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 428, "end" : 437, "pvalue" : 2.47E-5, "score" : 59.66, "motifNumber" : 4, "location-fragments" : [ { "start" : 428, "end" : 437, "dc-status" : "CONTINUOUS" } ] }, { "start" : 297, "end" : 314, "pvalue" : 1.6E-4, "score" : 30.41, "motifNumber" : 1, "location-fragments" : [ { "start" : 297, "end" : 314, "dc-status" : "CONTINUOUS" } ] }, { "start" : 351, "end" : 362, "pvalue" : 1.97E-4, "score" : 42.44, "motifNumber" : 3, "location-fragments" : [ { "start" : 351, "end" : 362, "dc-status" : "CONTINUOUS" } ] }, { "start" : 437, "end" : 448, "pvalue" : 3.52E-4, "score" : 39.54, "motifNumber" : 5, "location-fragments" : [ { "start" : 437, "end" : 448, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-10, "graphscan" : "I.III", "model-ac" : "PR00385" }, { "signature" : { "accession" : "G3DSA:1.10.630.10", "name" : "Cytochrome p450", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036396", "name" : "Cyt_P450_sf", "description" : "Cytochrome P450 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 248, "end" : 495, "hmmStart" : 227, "hmmEnd" : 453, "hmmLength" : 461, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-76, "score" : 258.8, "envelopeStart" : 248, "envelopeEnd" : 495, "postProcessed" : true, "location-fragments" : [ { "start" : 248, "end" : 495, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-93, "score" : 314.9, "model-ac" : "3ld6B00" }, { "signature" : { "accession" : "G3DSA:1.10.630.10", "name" : "Cytochrome p450", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036396", "name" : "Cyt_P450_sf", "description" : "Cytochrome P450 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 241, "hmmStart" : 45, "hmmEnd" : 241, "hmmLength" : 487, "hmmBounds" : "COMPLETE", "evalue" : 5.0E-27, "score" : 96.5, "envelopeStart" : 1, "envelopeEnd" : 241, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 241, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-105, "score" : 355.4, "model-ac" : "4d6zA00" }, { "signature" : { "accession" : "PTHR24291", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 490, "hmmStart" : 87, "hmmEnd" : 560, "hmmLength" : 562, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 492, "location-fragments" : [ { "start" : 10, "end" : 490, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-213, "familyName" : "CYTOCHROME P450 4G1-RELATED", "score" : 710.7, "model-ac" : "PTHR24291" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 211, "end" : 231, "location-fragments" : [ { "start" : 211, "end" : 231, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PR00463", "name" : "EP450I", "description" : "E-class P450 group I signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002401", "name" : "Cyt_P450_E_grp-I", "description" : "Cytochrome P450, E-class, group I", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 27, "pvalue" : 0.0723, "score" : 25.02, "motifNumber" : 1, "location-fragments" : [ { "start" : 8, "end" : 27, "dc-status" : "CONTINUOUS" } ] }, { "start" : 427, "end" : 437, "pvalue" : 2.58E-5, "score" : 55.67, "motifNumber" : 8, "location-fragments" : [ { "start" : 427, "end" : 437, "dc-status" : "CONTINUOUS" } ] }, { "start" : 350, "end" : 368, "pvalue" : 0.00951, "score" : 29.4, "motifNumber" : 6, "location-fragments" : [ { "start" : 350, "end" : 368, "dc-status" : "CONTINUOUS" } ] }, { "start" : 392, "end" : 416, "pvalue" : 3.72E-9, "score" : 33.52, "motifNumber" : 7, "location-fragments" : [ { "start" : 392, "end" : 416, "dc-status" : "CONTINUOUS" } ] }, { "start" : 286, "end" : 303, "pvalue" : 3.05E-4, "score" : 26.72, "motifNumber" : 4, "location-fragments" : [ { "start" : 286, "end" : 303, "dc-status" : "CONTINUOUS" } ] }, { "start" : 437, "end" : 460, "pvalue" : 1.55E-6, "score" : 26.07, "motifNumber" : 9, "location-fragments" : [ { "start" : 437, "end" : 460, "dc-status" : "CONTINUOUS" } ] }, { "start" : 306, "end" : 332, "pvalue" : 2.11E-6, "score" : 26.84, "motifNumber" : 5, "location-fragments" : [ { "start" : 306, "end" : 332, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-26, "graphscan" : "i..iiiIIi", "model-ac" : "PR00463" }, { "signature" : { "accession" : "PS00086", "name" : "CYTOCHROME_P450", "description" : "Cytochrome P450 cysteine heme-iron ligand signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017972", "name" : "Cyt_P450_CS", "description" : "Cytochrome P450, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 430, "end" : 439, "level" : "STRONG", "cigarAlignment" : "2M1I7M", "alignment" : "FGaGPRGCLG", "location-fragments" : [ { "start" : 430, "end" : 439, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00086" }, { "signature" : { "accession" : "PTHR24291:SF106", "name" : "CYTOCHROME P450 4G1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 490, "hmmStart" : 87, "hmmEnd" : 560, "hmmLength" : 562, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 492, "location-fragments" : [ { "start" : 10, "end" : 490, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-213, "familyName" : "CYTOCHROME P450 4G1-RELATED", "score" : 710.7, "model-ac" : "PTHR24291:SF106" }, { "signature" : { "accession" : "SSF48264", "name" : "Cytochrome P450", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036396", "name" : "Cyt_P450_sf", "description" : "Cytochrome P450 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 490, "hmmLength" : 463, "location-fragments" : [ { "start" : 6, "end" : 200, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 261, "end" : 490, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.13E-99, "model-ac" : "0054912" }, { "signature" : { "accession" : "PF00067", "name" : "p450", "description" : "Cytochrome P450", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001128", "name" : "Cyt_P450", "description" : "Cytochrome P450", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 463, "hmmStart" : 31, "hmmEnd" : 438, "hmmLength" : 463, "hmmBounds" : "INCOMPLETE", "evalue" : 2.4E-88, "score" : 296.9, "envelopeStart" : 1, "envelopeEnd" : 485, "postProcessed" : true, "location-fragments" : [ { "start" : 6, "end" : 463, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.2E-90, "score" : 302.4, "model-ac" : "PF00067" } ], "xref" : [ { "name" : "XP_018909841.1 PREDICTED: cytochrome P450 4g15-like isoform X3 [Bemisia tabaci]", "id" : "XP_018909841.1" } ] },{ "sequence" : "MSTARGPNVSVLHLRSTSEPWESCFPRNTAPARNSRLSQMNSACTVPSATLLKNAMATSNLARRKSAGLFASGVAEAKENGCSRELSPVRWCDQEVDGVFLGRSGWVQVQHKSLDRTPQKPQEPPTPPSRNLTHSHSLRYPLDSTPDPLEILNRPGYQFTSSQRVMQVSQLKTSKSEDSNAIISPPPAFQDHNQRFDTVNRPKTLASRSFNFTRSDAVEGSPPASPPFHRSWSASPHTPQGPRRKLTPSPGAKIPHTRSFDDATKTSSRRTQYHKYSSSSSSSSAGFRSFDSTLNRTMPKLCETDSSVYDDGDEDDNNSSLNLSAHSTMTVINSSPDSCAETKKREKYRRAKKAENFCTSPSSSSSSDYSPASSAPFRRSVSHNSHYLNSSKDSLVSHHSSDSVSRSNKVKRSRSLQLAADRVPPPGVPGPAPAVPPRNSEDPPRACPRPAPRTMADNYKQRILNGRSSKSEELEDEVRREAEEEARIITEYLYGSRSQEAARALLLHRYFDSPAADAASKKHKAKILHDQGIDIYLVPKNGDPQKPRLLARGAVTPLTKTLSPSEAYHTTSNANPCNPNTCDYWPQCAHPYPDPKPRPKARNLKPSNSYSNSDTEKRRGYPASAMSSPASLERVDDDSGYPEKVKRVVRAVRPCSNDSEMGLNLKRASSDAYRYRMMGEGRSPPKAPQRRVSSVDPPVPPPRAEVSSPLSSSGSSNGVGAVSASPLGERKSVGYAMGSPTMLAGSPVIPNGGHQWREAQQRSLSLPKSFQAATQTTQPKSGLFNWGKRSNANSSSQRQIPSNPSPEAARTAPPTPEREESIRNQASRLAKTTQYSSTPALDDPVNISDWNVDRWVESQDEPDKQNLDDPTRRNIQGNNVTESVLNKFRKSFSLRFAGNKKAGSKDGDEDVEIETIQRPDSPKDEGDPKFRFGPLVWRTSKERKKARKARSAKCNSGDSGIHIEMGGRIEDSSESHDTDILGDDDTDSPLMTRKRTTPTSSDGKPSRPSSDVINQLLLDKLKMDSRNILARSNGQPVRRTHSDLGGQRLLNWDYRFYRRRMLNTSPLKSRPPFMSSSCRGSRPIGMRSYKLRRSISQPLGLNELSPVMRKKPIVGRYNASEDERGGTSDDEMMSDSESSIASLNERKKSFEQATDEEVVVLAEAVWDHVAMEPEELMFRAGDVVEVKDTRDRDWWWGSAGGRSGWFPAAFVRLRVSQGDTVEDCLAALATGAGKSIQRRASISRLSNDEVRAKVVRELVHTERDFVKLLTDVAEGYLAECRRRTDMFTEDQINTIFSNLPNILRLQSSFLEDLESKIDWSASHKSCVGEVFLKHKSSFRMYSEYCNSHPLALSTLQDLYQLDSYSKFFEACRLMRGLIEIPLDGYLLTPIQRICKYPLQLAELLKYTKPDHPDHEQVSEALEAMKNVAVLINERKRRMESLEKLALWQQRVEGWDGVDLIEQSSQLIHQGEAVRMTSSRRTANIIIFLFDHQLIYCKKDILKRNTLVYKGRMPTDYCEIYSLPDGKDGSLGVNIRNGIKICASISEKTLVFCCRSEQEKGKWLEAFSEERKLVEQDKLDGLEFAPAARQLARTAAARCHRRPPSKPRNKYKRGAIEVNTSEVPHMNGTSHSSNRKAGSWWYPFGTSKSSSKKNRTFIRANNLQPIMHPA", "md5" : "080111f6fafc19d1a92429f93787c74b", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 674, "end" : 725, "location-fragments" : [ { "start" : 674, "end" : 725, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 424, "end" : 450, "location-fragments" : [ { "start" : 424, "end" : 450, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 852, "end" : 879, "location-fragments" : [ { "start" : 852, "end" : 879, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00326", "name" : "SH3_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001452", "name" : "SH3_domain", "description" : "SH3 domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1160, "end" : 1215, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 5.4E-14, "score" : 62.5, "location-fragments" : [ { "start" : 1160, "end" : 1215, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-14, "score" : 62.5, "model-ac" : "SM00326" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 593, "end" : 641, "location-fragments" : [ { "start" : 593, "end" : 641, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00233", "name" : "PH_update", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001849", "name" : "PH_domain", "description" : "Pleckstrin homology domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1466, "end" : 1573, "hmmStart" : 1, "hmmEnd" : 82, "hmmLength" : 82, "hmmBounds" : "COMPLETE", "evalue" : 5.3E-8, "score" : 42.6, "location-fragments" : [ { "start" : 1466, "end" : 1573, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-8, "score" : 42.6, "model-ac" : "SM00233" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 706, "end" : 722, "location-fragments" : [ { "start" : 706, "end" : 722, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 305, "end" : 329, "location-fragments" : [ { "start" : 305, "end" : 329, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.20.900.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR035899", "name" : "DBL_dom_sf", "description" : "Dbl homology (DH) domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1226, "end" : 1456, "hmmStart" : 23, "hmmEnd" : 237, "hmmLength" : 237, "hmmBounds" : "COMPLETE", "evalue" : 7.9E-78, "score" : 262.8, "envelopeStart" : 1226, "envelopeEnd" : 1456, "postProcessed" : true, "location-fragments" : [ { "start" : 1226, "end" : 1456, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-78, "score" : 263.6, "model-ac" : "2pz1A02" }, { "signature" : { "accession" : "G3DSA:2.30.29.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011993", "name" : "PH-like_dom_sf", "description" : "PH-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1458, "end" : 1635, "hmmStart" : 2, "hmmEnd" : 146, "hmmLength" : 155, "hmmBounds" : "COMPLETE", "evalue" : 1.0E-40, "score" : 140.7, "envelopeStart" : 1458, "envelopeEnd" : 1635, "postProcessed" : true, "location-fragments" : [ { "start" : 1458, "end" : 1635, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-41, "score" : 142.1, "model-ac" : "2dfkC02" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 901, "end" : 940, "location-fragments" : [ { "start" : 901, "end" : 940, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF07653", "name" : "SH3_2", "description" : "Variant SH3 domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001452", "name" : "SH3_domain", "description" : "SH3 domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1164, "end" : 1212, "hmmStart" : 4, "hmmEnd" : 55, "hmmLength" : 57, "hmmBounds" : "INCOMPLETE", "evalue" : 2.6E-9, "score" : 36.8, "envelopeStart" : 1161, "envelopeEnd" : 1214, "postProcessed" : true, "location-fragments" : [ { "start" : 1164, "end" : 1212, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.7E-10, "score" : 39.4, "model-ac" : "PF07653" }, { "signature" : { "accession" : "SSF50729", "name" : "PH domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 1441, "end" : 1589, "hmmLength" : 162, "location-fragments" : [ { "start" : 1441, "end" : 1589, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.21E-35, "model-ac" : "0053818" }, { "signature" : { "accession" : "SSF50044", "name" : "SH3-domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036028", "name" : "SH3-like_dom_sf", "description" : "SH3-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1159, "end" : 1214, "hmmLength" : 118, "location-fragments" : [ { "start" : 1159, "end" : 1214, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.38E-17, "model-ac" : "0041374" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 383, "end" : 403, "location-fragments" : [ { "start" : 383, "end" : 403, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00621", "name" : "RhoGEF", "description" : "RhoGEF domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000219", "name" : "DH-domain", "description" : "Dbl homology (DH) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "guanyl-nucleotide exchange factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005085" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1254, "end" : 1432, "hmmStart" : 1, "hmmEnd" : 183, "hmmLength" : 183, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-44, "score" : 152.1, "envelopeStart" : 1254, "envelopeEnd" : 1432, "postProcessed" : true, "location-fragments" : [ { "start" : 1254, "end" : 1432, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-44, "score" : 152.9, "model-ac" : "PF00621" }, { "signature" : { "accession" : "SM00325", "name" : "RhoGEF_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000219", "name" : "DH-domain", "description" : "Dbl homology (DH) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "guanyl-nucleotide exchange factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005085" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1254, "end" : 1433, "hmmStart" : 1, "hmmEnd" : 211, "hmmLength" : 211, "hmmBounds" : "COMPLETE", "evalue" : 3.6E-55, "score" : 199.3, "location-fragments" : [ { "start" : 1254, "end" : 1433, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-55, "score" : 199.3, "model-ac" : "SM00325" }, { "signature" : { "accession" : "cd01224", "name" : "PH_Collybistin_ASEF", "description" : "PH_Collybistin_ASEF", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1438, "end" : 1576, "sites" : [ ], "evalue" : 5.24023E-57, "score" : 191.704, "location-fragments" : [ { "start" : 1438, "end" : 1576, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01224" }, { "signature" : { "accession" : "PS00741", "name" : "DH_1", "description" : "Dbl homology (DH) domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR001331", "name" : "GDS_CDC24_CS", "description" : "Guanine-nucleotide dissociation stimulator, CDC24, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" }, { "name" : "guanyl-nucleotide exchange factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005085" } ], "pathwayXRefs" : [ { "name" : "NRAGE signals death through JNK", "databaseName" : "Reactome", "id" : "R-HSA-193648" }, { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" }, { "name" : "G alpha (12/13) signalling events", "databaseName" : "Reactome", "id" : "R-HSA-416482" } ] } }, "locations" : [ { "start" : 1382, "end" : 1407, "level" : "STRONG", "cigarAlignment" : "1M2I2M2I2M2I1M1I1M2I1M1I1M1I2M3I1M", "alignment" : "LdgYLltPIqrIcKypLqLaELlkyT", "location-fragments" : [ { "start" : 1382, "end" : 1407, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00741" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 168, "end" : 279, "location-fragments" : [ { "start" : 168, "end" : 279, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR45834:SF3", "name" : "RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3, ISOFORM L", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1038, "end" : 1653, "hmmStart" : 863, "hmmEnd" : 1576, "hmmLength" : 1596, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1024, "envelopeEnd" : 1666, "location-fragments" : [ { "start" : 1038, "end" : 1653, "dc-status" : "CONTINUOUS" } ] }, { "start" : 194, "end" : 965, "hmmStart" : 604, "hmmEnd" : 891, "hmmLength" : 1596, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 130, "envelopeEnd" : 980, "location-fragments" : [ { "start" : 194, "end" : 965, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-195, "familyName" : "RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3, ISOFORM L", "score" : 654.3, "model-ac" : "PTHR45834:SF3" }, { "signature" : { "accession" : "PS50003", "name" : "PH_DOMAIN", "description" : "PH domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001849", "name" : "PH_domain", "description" : "Pleckstrin homology domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1465, "end" : 1571, "score" : 9.17, "alignment" : "QLIHQGEAVRMTSS--RRTANIIIFLFDHQLIYCKKDiLKRNTLVYKGRMPTDYCEIYSLPDGKDGSlgvnIRNGIKICASISEKTLVFCCRSEQEKGKWLEAFSEERK", "location-fragments" : [ { "start" : 1465, "end" : 1571, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50003" }, { "signature" : { "accession" : "G3DSA:2.30.30.40", "name" : "SH3 Domains", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1149, "end" : 1216, "hmmStart" : 6, "hmmEnd" : 67, "hmmLength" : 69, "hmmBounds" : "COMPLETE", "evalue" : 5.5E-22, "score" : 79.1, "envelopeStart" : 1149, "envelopeEnd" : 1216, "postProcessed" : true, "location-fragments" : [ { "start" : 1149, "end" : 1216, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-22, "score" : 80.2, "model-ac" : "2dx1A01" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 992, "end" : 1013, "location-fragments" : [ { "start" : 992, "end" : 1013, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF48065", "name" : "DBL homology domain (DH-domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035899", "name" : "DBL_dom_sf", "description" : "Dbl homology (DH) domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1248, "end" : 1455, "hmmLength" : 234, "location-fragments" : [ { "start" : 1248, "end" : 1455, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.75E-59, "model-ac" : "0044151" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 756, "end" : 806, "location-fragments" : [ { "start" : 756, "end" : 806, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1115, "end" : 1131, "location-fragments" : [ { "start" : 1115, "end" : 1131, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 383, "end" : 478, "location-fragments" : [ { "start" : 383, "end" : 478, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00160", "name" : "RhoGEF", "description" : "RhoGEF", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000219", "name" : "DH-domain", "description" : "Dbl homology (DH) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "guanyl-nucleotide exchange factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005085" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1251, "end" : 1432, "sites" : [ { "description" : "GTPase interaction site", "numLocations" : 16, "siteLocations" : [ { "start" : 1388, "end" : 1388, "residue" : "T" }, { "start" : 1402, "end" : 1402, "residue" : "E" }, { "start" : 1428, "end" : 1428, "residue" : "A" }, { "start" : 1356, "end" : 1356, "residue" : "Q" }, { "start" : 1383, "end" : 1383, "residue" : "D" }, { "start" : 1399, "end" : 1399, "residue" : "Q" }, { "start" : 1257, "end" : 1257, "residue" : "E" }, { "start" : 1432, "end" : 1432, "residue" : "N" }, { "start" : 1395, "end" : 1395, "residue" : "K" }, { "start" : 1387, "end" : 1387, "residue" : "L" }, { "start" : 1384, "end" : 1384, "residue" : "G" }, { "start" : 1394, "end" : 1394, "residue" : "C" }, { "start" : 1391, "end" : 1391, "residue" : "Q" }, { "start" : 1398, "end" : 1398, "residue" : "L" }, { "start" : 1261, "end" : 1261, "residue" : "T" }, { "start" : 1390, "end" : 1390, "residue" : "I" } ] } ], "evalue" : 3.88453E-57, "score" : 193.668, "location-fragments" : [ { "start" : 1251, "end" : 1432, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00160" }, { "signature" : { "accession" : "PS50002", "name" : "SH3", "description" : "Src homology 3 (SH3) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001452", "name" : "SH3_domain", "description" : "SH3 domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1157, "end" : 1216, "score" : 21.702, "alignment" : "EVVVLAEAVWDHVAMEPEELMFRAGDVVEVKDTRDRDWWWGSAG-GRSGWFPAAFVRLRVS", "location-fragments" : [ { "start" : 1157, "end" : 1216, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50002" }, { "signature" : { "accession" : "PTHR45834", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1038, "end" : 1653, "hmmStart" : 863, "hmmEnd" : 1576, "hmmLength" : 1596, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1024, "envelopeEnd" : 1666, "location-fragments" : [ { "start" : 1038, "end" : 1653, "dc-status" : "CONTINUOUS" } ] }, { "start" : 194, "end" : 965, "hmmStart" : 604, "hmmEnd" : 891, "hmmLength" : 1596, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 130, "envelopeEnd" : 980, "location-fragments" : [ { "start" : 194, "end" : 965, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-195, "familyName" : "RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3, ISOFORM L", "score" : 654.3, "model-ac" : "PTHR45834" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 471, "end" : 491, "location-fragments" : [ { "start" : 471, "end" : 491, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 110, "end" : 147, "location-fragments" : [ { "start" : 110, "end" : 147, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 901, "end" : 1013, "location-fragments" : [ { "start" : 901, "end" : 1013, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 168, "end" : 218, "location-fragments" : [ { "start" : 168, "end" : 218, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1133, "end" : 1153, "location-fragments" : [ { "start" : 1133, "end" : 1153, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1115, "end" : 1147, "location-fragments" : [ { "start" : 1115, "end" : 1147, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 604, "end" : 618, "location-fragments" : [ { "start" : 604, "end" : 618, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 746, "end" : 823, "location-fragments" : [ { "start" : 746, "end" : 823, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50010", "name" : "DH_2", "description" : "Dbl homology (DH) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000219", "name" : "DH-domain", "description" : "Dbl homology (DH) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "guanyl-nucleotide exchange factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005085" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1250, "end" : 1434, "score" : 34.148, "alignment" : "VRAKVVRELVHTERDFVKLLTDVAEGYLAECRRRTDM-FTEDQINTIFSNLPNILRLQ-SSFLEDLESKIDWSaSHKSCVGEVFLKHKS-SFRMYSEYCNSHPLALSTLQDLYQLDSysKFFEACRLMRGLIE--IPLDGYLLTPIQRICKYPLQLAELLKYTKPDHPDHEQVSEALEAMKNVAVLINER", "location-fragments" : [ { "start" : 1250, "end" : 1434, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50010" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 854, "end" : 870, "location-fragments" : [ { "start" : 854, "end" : 870, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd11828", "name" : "SH3_ARHGEF9_like", "description" : "SH3_ARHGEF9_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1161, "end" : 1213, "sites" : [ { "description" : "DH-PH interface", "numLocations" : 8, "siteLocations" : [ { "start" : 1173, "end" : 1173, "residue" : "P" }, { "start" : 1171, "end" : 1171, "residue" : "M" }, { "start" : 1209, "end" : 1209, "residue" : "A" }, { "start" : 1164, "end" : 1164, "residue" : "A" }, { "start" : 1212, "end" : 1212, "residue" : "R" }, { "start" : 1165, "end" : 1165, "residue" : "V" }, { "start" : 1170, "end" : 1170, "residue" : "A" }, { "start" : 1163, "end" : 1163, "residue" : "E" } ] }, { "description" : "peptide ligand binding site", "numLocations" : 9, "siteLocations" : [ { "start" : 1193, "end" : 1193, "residue" : "D" }, { "start" : 1171, "end" : 1171, "residue" : "M" }, { "start" : 1175, "end" : 1175, "residue" : "E" }, { "start" : 1209, "end" : 1209, "residue" : "A" }, { "start" : 1194, "end" : 1194, "residue" : "W" }, { "start" : 1210, "end" : 1210, "residue" : "F" }, { "start" : 1168, "end" : 1168, "residue" : "H" }, { "start" : 1207, "end" : 1207, "residue" : "P" }, { "start" : 1166, "end" : 1166, "residue" : "W" } ] } ], "evalue" : 5.24749E-29, "score" : 108.623, "location-fragments" : [ { "start" : 1161, "end" : 1213, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd11828" } ], "xref" : [ { "name" : "XP_018910365.1 PREDICTED: uncharacterized protein LOC109039360 isoform X2 [Bemisia tabaci]", "id" : "XP_018910365.1" } ] },{ "sequence" : "MNHFVSNQVTPALKSAWYLRNLCGCQSRTGSARTCDLVFKLPCPLMSLRCTRFYGTYHSRCLGASSSVLQNSTDTKYDTGTFRNSAAPVQLHSLDLSRSFRTFSPLYCSPLKPSSRVEETVSALKEKAKEKVEATKKEQAAEPTVVAVPPKKSLKQKIKDELLHYYHGFRLLGIDIKVSSKLVWRVLNGKSLSRREYNLLVRTMSDMFRLVPFSVFIIVPFMEFLLPVFIKFFPGMLPSTFQTSSDKEAKIVQNLKIKLEMAKFLQKTLDNMSVHGVDDGNPSESAAKLAEFFKKVKESRGMVTSEEILKISKLFRDEITLDSLSKPQLAALCRVLEIQPIGTSNVLRFQLRMKLRSLAADDIWIRKEGIDSLSVSELQAACRARGMRAYGLTAERLKEQLEQWIHLSLNEKVPPSLLLLSRALMLSSSDVPLDQIKATISALPETMVSSVQAEIGEIEGKPDNKLKIALIQEEVRKISEERKEEYEELKAEKKETVKDPELLEDKAPELTDTTGIAPTPVTVAKAPADVPVRETVTEKVVPDIVAQGSAVQKEEELTSKDLAQIEDAISVLTVNGKKKLLVEKDELEQLKEELADYQADVLELKEALKETDPTHVIPKVKESKAANRLFKRMNKMINKLDHVRDNLEKKGAEIKKTLEVETVEDKKSDELVKIDELLSAIQKIQTLPDSSKLEKIAEVLSEIDKDHDGLIRIDVVLRVLELIGNENVKLNKKQIDELIELVAKEEMIELEEHIAQALKQDMQKSKEDKESESQNPKSGSSSSSSSSSESSSNDSKSSQNKIKKSTLEMTKEITEKTRKSDDSSGDKQSCNVPPPKQTVSVKSVDIQKKSDPLKPNNEPKNL", "md5" : "2b251d6d727f7932ab71db375abd2863", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 759, "end" : 862, "location-fragments" : [ { "start" : 759, "end" : 862, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 775, "end" : 804, "location-fragments" : [ { "start" : 775, "end" : 804, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 826, "end" : 845, "location-fragments" : [ { "start" : 826, "end" : 845, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR14009:SF1", "name" : "MITOCHONDRIAL PROTON/CALCIUM EXCHANGER PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 115, "end" : 644, "hmmStart" : 88, "hmmEnd" : 549, "hmmLength" : 554, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 54, "envelopeEnd" : 665, "location-fragments" : [ { "start" : 115, "end" : 644, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-159, "familyName" : "MITOCHONDRIAL PROTON/CALCIUM EXCHANGER PROTEIN", "score" : 533.0, "model-ac" : "PTHR14009:SF1" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 759, "end" : 774, "location-fragments" : [ { "start" : 759, "end" : 774, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 468, "end" : 499, "location-fragments" : [ { "start" : 468, "end" : 499, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 630, "end" : 650, "location-fragments" : [ { "start" : 630, "end" : 650, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 748, "end" : 775, "location-fragments" : [ { "start" : 748, "end" : 775, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR14009", "name" : "LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 115, "end" : 644, "hmmStart" : 88, "hmmEnd" : 549, "hmmLength" : 554, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 54, "envelopeEnd" : 665, "location-fragments" : [ { "start" : 115, "end" : 644, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-159, "familyName" : "MITOCHONDRIAL PROTON/CALCIUM EXCHANGER PROTEIN", "score" : 533.0, "model-ac" : "PTHR14009" }, { "signature" : { "accession" : "PS51758", "name" : "LETM1_RBD", "description" : "Letm1 ribosome-binding (RBD) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR033122", "name" : "LETM1_RBD", "description" : "Letm1 ribosome-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "ribosome binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0043022" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 253, "end" : 445, "score" : 27.395, "alignment" : "QNLKIKLEMAKFLQKTLDNMSVHGVDDGNPSesAAKLAEFFKKVKESRGMVTSEEILKISKLFRDEITLDSLSKPQLAALCRVLEIQPIGTSNVLRFQLRMKLRSLAADDIWIRKEGIDSLSVSELQAACRARGMRAYGLTAERLKEQLEQWIHLSLNEKVPPSLLLLSRALMLS------------------------------------SSDVPLDQIKATISALPE", "location-fragments" : [ { "start" : 253, "end" : 445, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51758" }, { "signature" : { "accession" : "PF07766", "name" : "LETM1", "description" : "LETM1-like protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR011685", "name" : "LETM1", "description" : "LETM1-like", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 155, "end" : 421, "hmmStart" : 2, "hmmEnd" : 267, "hmmLength" : 267, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.8E-103, "score" : 345.5, "envelopeStart" : 154, "envelopeEnd" : 421, "postProcessed" : true, "location-fragments" : [ { "start" : 155, "end" : 421, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-103, "score" : 345.5, "model-ac" : "PF07766" }, { "signature" : { "accession" : "PS50222", "name" : "EF_HAND_2", "description" : "EF-hand calcium-binding domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002048", "name" : "EF_hand_dom", "description" : "EF-hand domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 691, "end" : 726, "score" : 10.385, "alignment" : "SKLEKIAEVLSEIDKDHDGLIRIDVVLRVLElIGnE", "location-fragments" : [ { "start" : 691, "end" : 726, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50222" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 577, "end" : 607, "location-fragments" : [ { "start" : 577, "end" : 607, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 805, "end" : 825, "location-fragments" : [ { "start" : 805, "end" : 825, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF47473", "name" : "EF-hand", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011992", "name" : "EF-hand-dom_pair", "description" : "EF-hand domain pair", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 647, "end" : 742, "hmmLength" : 140, "location-fragments" : [ { "start" : 647, "end" : 742, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.09E-7, "model-ac" : "0038094" } ], "xref" : [ { "name" : "XP_018909892.1 PREDICTED: LETM1 and EF-hand domain-containing protein 1, mitochondrial [Bemisia tabaci]", "id" : "XP_018909892.1" } ] },{ "sequence" : "MNAPPTFESFLLFEGEKKVIKEVESKVQNAAIFTINKEDHTLGNMIRDQLLKDPQVLFAGYKVPHPLEHKFVLRIQTSSADYRPEEALVNAITDLIAELSLFEERFKDAVKEKKEGLD", "md5" : "ef448f687426e9ac5ac26d47dc312a3e", "matches" : [ { "signature" : { "accession" : "PF13656", "name" : "RNA_pol_L_2", "description" : "RNA polymerase Rpb3/Rpb11 dimerisation domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR009025", "name" : "RBP11-like_dimer", "description" : "DNA-directed RNA polymerase, RBP11-like dimerisation domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006351" }, { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 31, "end" : 105, "hmmStart" : 2, "hmmEnd" : 75, "hmmLength" : 75, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.9E-29, "score" : 100.3, "envelopeStart" : 30, "envelopeEnd" : 105, "postProcessed" : true, "location-fragments" : [ { "start" : 31, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-29, "score" : 100.7, "model-ac" : "PF13656" }, { "signature" : { "accession" : "PTHR13946:SF31", "name" : "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 111, "hmmStart" : 1, "hmmEnd" : 110, "hmmLength" : 144, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 117, "location-fragments" : [ { "start" : 1, "end" : 111, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-49, "familyName" : "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A-RELATED", "score" : 170.8, "model-ac" : "PTHR13946:SF31" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 107, "end" : 118, "location-fragments" : [ { "start" : 107, "end" : 118, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "G3DSA:3.30.1360.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036603", "name" : "RBP11-like", "description" : "RNA polymerase, RBP11-like subunit", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006351" }, { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 118, "hmmStart" : 1, "hmmEnd" : 116, "hmmLength" : 117, "hmmBounds" : "COMPLETE", "evalue" : 6.0E-47, "score" : 160.0, "envelopeStart" : 1, "envelopeEnd" : 118, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 118, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-47, "score" : 160.1, "model-ac" : "5flmK00" }, { "signature" : { "accession" : "PTHR13946", "name" : "DNA-DIRECTED RNA POLYMERASE I,II,III", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 111, "hmmStart" : 1, "hmmEnd" : 110, "hmmLength" : 144, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 117, "location-fragments" : [ { "start" : 1, "end" : 111, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-49, "familyName" : "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A-RELATED", "score" : 170.8, "model-ac" : "PTHR13946" }, { "signature" : { "accession" : "cd06926", "name" : "RNAP_II_RPB11", "description" : "RNAP_II_RPB11", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR037685", "name" : "RBP11", "description" : "RNA polymerase RBP11", "type" : "FAMILY", "goXRefs" : [ { "name" : "RNA polymerase II, core complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005665" }, { "name" : "RNA polymerase II activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0001055" }, { "name" : "transcription by RNA polymerase II", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006366" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 106, "sites" : [ { "description" : "RPB11 - RPB3 heterodimer interface", "numLocations" : 19, "siteLocations" : [ { "start" : 42, "end" : 42, "residue" : "L" }, { "start" : 92, "end" : 92, "residue" : "I" }, { "start" : 103, "end" : 103, "residue" : "E" }, { "start" : 100, "end" : 100, "residue" : "S" }, { "start" : 39, "end" : 39, "residue" : "D" }, { "start" : 99, "end" : 99, "residue" : "L" }, { "start" : 102, "end" : 102, "residue" : "F" }, { "start" : 41, "end" : 41, "residue" : "T" }, { "start" : 49, "end" : 49, "residue" : "Q" }, { "start" : 21, "end" : 21, "residue" : "K" }, { "start" : 105, "end" : 105, "residue" : "R" }, { "start" : 35, "end" : 35, "residue" : "I" }, { "start" : 106, "end" : 106, "residue" : "F" }, { "start" : 98, "end" : 98, "residue" : "E" }, { "start" : 52, "end" : 52, "residue" : "K" }, { "start" : 93, "end" : 93, "residue" : "T" }, { "start" : 44, "end" : 44, "residue" : "N" }, { "start" : 19, "end" : 19, "residue" : "V" }, { "start" : 104, "end" : 104, "residue" : "E" } ] }, { "description" : "RPB11 - RPB8 interaction site", "numLocations" : 1, "siteLocations" : [ { "start" : 57, "end" : 57, "residue" : "L" } ] }, { "description" : "RPB11 - RPB2 interaction site", "numLocations" : 3, "siteLocations" : [ { "start" : 65, "end" : 65, "residue" : "H" }, { "start" : 40, "end" : 40, "residue" : "H" }, { "start" : 66, "end" : 66, "residue" : "P" } ] }, { "description" : "RPB11 - RPB1 interaction site", "numLocations" : 10, "siteLocations" : [ { "start" : 64, "end" : 64, "residue" : "P" }, { "start" : 26, "end" : 26, "residue" : "K" }, { "start" : 60, "end" : 60, "residue" : "G" }, { "start" : 65, "end" : 65, "residue" : "H" }, { "start" : 61, "end" : 61, "residue" : "Y" }, { "start" : 62, "end" : 62, "residue" : "K" }, { "start" : 58, "end" : 58, "residue" : "F" }, { "start" : 67, "end" : 67, "residue" : "L" }, { "start" : 47, "end" : 47, "residue" : "R" }, { "start" : 66, "end" : 66, "residue" : "P" } ] } ], "evalue" : 4.81475E-51, "score" : 154.672, "location-fragments" : [ { "start" : 14, "end" : 106, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd06926" }, { "signature" : { "accession" : "PS01154", "name" : "RNA_POL_L_13KD", "description" : "RNA polymerases L / 13 to 16 Kd subunits signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR008193", "name" : "RNA_pol_Rpb11_13-16kDa_CS", "description" : "DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006351" }, { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" }, { "name" : "DNA-directed 5'-3' RNA polymerase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003899" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 35, "end" : 66, "level" : "STRONG", "cigarAlignment" : "1M2I1M1I3M1I1M1I1M3I1M5I1M4I1M3I2M", "alignment" : "InkEdHTLgNmIrdqLlkdpqVlfagYkvpHP", "location-fragments" : [ { "start" : 35, "end" : 66, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01154" }, { "signature" : { "accession" : "SSF55257", "name" : "RBP11-like subunits of RNA polymerase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036603", "name" : "RBP11-like", "description" : "RNA polymerase, RBP11-like subunit", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006351" }, { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 113, "hmmLength" : 114, "location-fragments" : [ { "start" : 1, "end" : 113, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.68E-37, "model-ac" : "0038879" } ], "xref" : [ { "name" : "XP_018910255.1 PREDICTED: DNA-directed RNA polymerase II subunit RPB11 [Bemisia tabaci]", "id" : "XP_018910255.1" } ] },{ "sequence" : "MLTVNDPGSGLGYVLSACVLLASFNSPAYGTEDPEAHNLRHQRLQPEFAGPIDNLTVPVGKEVSLSCVVNNLGEHKVGWLRSRDQTILTLHTRVVTHSPRISISFDNHRTFTLHISRVKESDKGCYMCQVNTPEMKKQSGCIDVHVPPDIISEYSSSDTAVNEGDNVTLSCHATGHPQPIVTWRRENGEPMLIRKNVRDLTLVDVHRGKTLFLWKVDRRQMGAYLCIAANEVPPAVSKRVIVSVNFQPTIVIPNQLVGSPLGKEVHLECYAEAYPKTINYWVKNRGEILLEGAKYTIQENRSVYKVYMSLFIKDFNMSDVGTYNCVATNSLGRAEATIRLYNLTGAGGSGQDHPEDSENSARCSKHSIRPFLLILCLLYVSRFLSSR", "md5" : "98d766a591ae6e290cd7128a0cc22ccd", "matches" : [ { "signature" : { "accession" : "PS50835", "name" : "IG_LIKE", "description" : "Ig-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR007110", "name" : "Ig-like_dom", "description" : "Immunoglobulin-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 248, "end" : 339, "score" : 10.571, "alignment" : "PTIVIPNQLVGSPLGKEVHLECYAEA-YPKTINYWVKNRGeillEGAKYTIQENRSVYKVYMSLFIKDFNMSDVGTYNCVATN--SLGRAEATIR", "location-fragments" : [ { "start" : 248, "end" : 339, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50835" }, { "signature" : { "accession" : "PTHR12231:SF235", "name" : "DPR-INTERACTING PROTEIN GAMMA", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 43, "end" : 352, "hmmStart" : 18, "hmmEnd" : 348, "hmmLength" : 400, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 26, "envelopeEnd" : 385, "location-fragments" : [ { "start" : 43, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-138, "familyName" : "DPR-INTERACTING PROTEIN GAMMA", "score" : 463.4, "model-ac" : "PTHR12231:SF235" }, { "signature" : { "accession" : "SSF48726", "name" : "Immunoglobulin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036179", "name" : "Ig-like_dom_sf", "description" : "Immunoglobulin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 247, "end" : 341, "hmmLength" : 111, "location-fragments" : [ { "start" : 247, "end" : 341, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.08E-17, "model-ac" : "0035573" }, { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 151, "end" : 243, "hmmStart" : 5, "hmmEnd" : 94, "hmmLength" : 96, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 8.1E-21, "score" : 76.0, "envelopeStart" : 151, "envelopeEnd" : 245, "postProcessed" : true, "location-fragments" : [ { "start" : 151, "end" : 243, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-49, "score" : 168.1, "model-ac" : "5eo9B02" }, { "signature" : { "accession" : "SM00408", "name" : "igc2_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003598", "name" : "Ig_sub2", "description" : "Immunoglobulin subtype 2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 260, "end" : 332, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 56, "hmmBounds" : "COMPLETE", "evalue" : 0.041, "score" : 20.4, "location-fragments" : [ { "start" : 260, "end" : 332, "dc-status" : "CONTINUOUS" } ] }, { "start" : 162, "end" : 233, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 56, "hmmBounds" : "COMPLETE", "evalue" : 6.6E-8, "score" : 42.3, "location-fragments" : [ { "start" : 162, "end" : 233, "dc-status" : "CONTINUOUS" } ] }, { "start" : 58, "end" : 135, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 56, "hmmBounds" : "COMPLETE", "evalue" : 0.18, "score" : 14.4, "location-fragments" : [ { "start" : 58, "end" : 135, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-18, "score" : 77.1, "model-ac" : "SM00408" }, { "signature" : { "accession" : "PF07679", "name" : "I-set", "description" : "Immunoglobulin I-set domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013098", "name" : "Ig_I-set", "description" : "Immunoglobulin I-set", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 250, "end" : 340, "hmmStart" : 3, "hmmEnd" : 88, "hmmLength" : 90, "hmmBounds" : "INCOMPLETE", "evalue" : 5.1E-12, "score" : 45.7, "envelopeStart" : 248, "envelopeEnd" : 341, "postProcessed" : true, "location-fragments" : [ { "start" : 250, "end" : 340, "dc-status" : "CONTINUOUS" } ] }, { "start" : 46, "end" : 139, "hmmStart" : 1, "hmmEnd" : 83, "hmmLength" : 90, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.5E-11, "score" : 44.2, "envelopeStart" : 46, "envelopeEnd" : 146, "postProcessed" : true, "location-fragments" : [ { "start" : 46, "end" : 139, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-41, "score" : 138.7, "model-ac" : "PF07679" }, { "signature" : { "accession" : "SM00409", "name" : "IG_3c", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003599", "name" : "Ig_sub", "description" : "Immunoglobulin subtype", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 52, "end" : 147, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-8, "score" : 44.0, "location-fragments" : [ { "start" : 52, "end" : 147, "dc-status" : "CONTINUOUS" } ] }, { "start" : 156, "end" : 245, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-7, "score" : 41.4, "location-fragments" : [ { "start" : 156, "end" : 245, "dc-status" : "CONTINUOUS" } ] }, { "start" : 253, "end" : 343, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 0.029, "score" : 23.5, "location-fragments" : [ { "start" : 253, "end" : 343, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-28, "score" : 108.9, "model-ac" : "SM00409" }, { "signature" : { "accession" : "PS50835", "name" : "IG_LIKE", "description" : "Ig-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR007110", "name" : "Ig-like_dom", "description" : "Immunoglobulin-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 148, "end" : 237, "score" : 12.713, "alignment" : "PDIISEYssSDTAVNEGDNVTLSCHATG-HPQPIVTWRRENG--------EPMLIrknvrdltlvdVHRGKTLFLWKVDRRQMGAYLCIAAN-----EVPPAVS", "location-fragments" : [ { "start" : 148, "end" : 237, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50835" }, { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 244, "end" : 342, "hmmStart" : 16, "hmmEnd" : 104, "hmmLength" : 107, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.8E-19, "score" : 71.6, "envelopeStart" : 242, "envelopeEnd" : 342, "postProcessed" : true, "location-fragments" : [ { "start" : 244, "end" : 342, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-47, "score" : 161.7, "model-ac" : "4pgzA01" }, { "signature" : { "accession" : "PTHR12231", "name" : "CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 43, "end" : 352, "hmmStart" : 18, "hmmEnd" : 348, "hmmLength" : 400, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 26, "envelopeEnd" : 385, "location-fragments" : [ { "start" : 43, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-138, "familyName" : "DPR-INTERACTING PROTEIN GAMMA", "score" : 463.4, "model-ac" : "PTHR12231" }, { "signature" : { "accession" : "SSF48726", "name" : "Immunoglobulin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036179", "name" : "Ig-like_dom_sf", "description" : "Immunoglobulin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 151, "hmmLength" : 126, "location-fragments" : [ { "start" : 46, "end" : 151, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.91E-17, "model-ac" : "0042359" }, { "signature" : { "accession" : "SM00406", "name" : "igv1_8", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013106", "name" : "Ig_V-set", "description" : "Immunoglobulin V-set domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 62, "end" : 130, "hmmStart" : 1, "hmmEnd" : 76, "hmmLength" : 76, "hmmBounds" : "COMPLETE", "evalue" : 7.7E-6, "score" : 35.4, "location-fragments" : [ { "start" : 62, "end" : 130, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.7E-6, "score" : 35.4, "model-ac" : "SM00406" }, { "signature" : { "accession" : "SSF48726", "name" : "Immunoglobulin", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036179", "name" : "Ig-like_dom_sf", "description" : "Immunoglobulin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 147, "end" : 252, "hmmLength" : 111, "location-fragments" : [ { "start" : 147, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.98E-17, "model-ac" : "0035573" }, { "signature" : { "accession" : "G3DSA:2.60.40.10", "name" : "Immunoglobulins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013783", "name" : "Ig-like_fold", "description" : "Immunoglobulin-like fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 150, "hmmStart" : 4, "hmmEnd" : 109, "hmmLength" : 110, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-32, "score" : 112.9, "envelopeStart" : 42, "envelopeEnd" : 150, "postProcessed" : true, "location-fragments" : [ { "start" : 42, "end" : 150, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.6E-54, "score" : 182.0, "model-ac" : "5eo9B01" }, { "signature" : { "accession" : "PS50835", "name" : "IG_LIKE", "description" : "Ig-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR007110", "name" : "Ig-like_dom", "description" : "Immunoglobulin-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 139, "score" : 10.644, "alignment" : "PEFAGPIDNLTVPVGKEVSLSCVVNN-LGEHKVGWLRS----------RDQTIltlhtrvvthsprisisfdNHRTFTLHISRVKESDKGCYMCQVN-----TPEMKKQS", "location-fragments" : [ { "start" : 46, "end" : 139, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50835" }, { "signature" : { "accession" : "PF13927", "name" : "Ig_3", "description" : "Immunoglobulin domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 147, "end" : 230, "hmmStart" : 1, "hmmEnd" : 79, "hmmLength" : 79, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-13, "score" : 51.4, "envelopeStart" : 147, "envelopeEnd" : 230, "postProcessed" : true, "location-fragments" : [ { "start" : 147, "end" : 230, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-38, "score" : 128.9, "model-ac" : "PF13927" } ], "xref" : [ { "name" : "XP_018910312.1 PREDICTED: lachesin-like isoform X3 [Bemisia tabaci]", "id" : "XP_018910312.1" } ] },{ "sequence" : "MEWQSQLIIVLKFLVVCLFVRHVGAKGFKNPETGTAWKIVKSTPEPNFEPYLLSTSQLIREEGFLVEEHAAQTEDGYILGLHRIVNPAAKNSSRPPVLIMHGFLIASDNWLIQGRDHDLPYLMADAGFDVWLGDFRGNCYSRRHETLSPNDDLFWDFGPHEWGYYDLPAMIEYIRHETKKQQITYVGYSIGGGAFYLMCSTRPYYNNYITSAIMLAPFVYGPREKKIRNNLLNFAKHAIKGHKQHERFEVFKRTPIHLKAVQRLTRIDAPSFKIMFLLFMDFFGDDIDQLDMLKFKQIASAFGAGTSLKAMEHMVQLYESREFRKFDFGRTRNKKYYGTIEPPQYNLTKVTVPSCIYYGANDYFVDFESIERLSKILPNVVKKKMVPHKKFNHLDFLVATDAKALLYDDVISDAFRIINSE", "md5" : "6e1b4814eb140440349fc5feedc1efb1", "matches" : [ { "signature" : { "accession" : "PIRSF000862", "name" : "Steryl_ester_lip", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR025483", "name" : "Lipase_euk", "description" : "Lipase, eukaryotic", "type" : "FAMILY", "goXRefs" : [ { "name" : "hydrolase activity, acting on ester bonds", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016788" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4, "end" : 416, "hmmStart" : 13, "hmmEnd" : 412, "hmmLength" : 408, "hmmBounds" : "INCOMPLETE", "evalue" : 6.7E-104, "score" : 343.6, "envelopeStart" : 4, "envelopeEnd" : 416, "postProcessed" : false, "location-fragments" : [ { "start" : 4, "end" : 416, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-104, "score" : 344.0, "model-ac" : "PIRSF000862" }, { "signature" : { "accession" : "G3DSA:3.40.50.1820", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 47, "end" : 413, "hmmStart" : 14, "hmmEnd" : 372, "hmmLength" : 377, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-110, "score" : 370.7, "envelopeStart" : 47, "envelopeEnd" : 413, "postProcessed" : true, "location-fragments" : [ { "start" : 47, "end" : 413, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-110, "score" : 371.1, "model-ac" : "1k8qA00" }, { "signature" : { "accession" : "PTHR11005:SF100", "name" : "LIPASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 54, "end" : 413, "hmmStart" : 14, "hmmEnd" : 360, "hmmLength" : 366, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 16, "envelopeEnd" : 417, "location-fragments" : [ { "start" : 54, "end" : 413, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-98, "familyName" : "LIPASE", "score" : 331.3, "model-ac" : "PTHR11005:SF100" }, { "signature" : { "accession" : "PF00561", "name" : "Abhydrolase_1", "description" : "alpha/beta hydrolase fold", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000073", "name" : "AB_hydrolase_1", "description" : "Alpha/beta hydrolase fold-1", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 95, "end" : 387, "hmmStart" : 1, "hmmEnd" : 247, "hmmLength" : 257, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.5E-18, "score" : 67.4, "envelopeStart" : 95, "envelopeEnd" : 398, "postProcessed" : true, "location-fragments" : [ { "start" : 95, "end" : 387, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.5E-20, "score" : 71.3, "model-ac" : "PF00561" }, { "signature" : { "accession" : "PTHR11005", "name" : "LYSOSOMAL ACID LIPASE-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 54, "end" : 413, "hmmStart" : 14, "hmmEnd" : 360, "hmmLength" : 366, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 16, "envelopeEnd" : 417, "location-fragments" : [ { "start" : 54, "end" : 413, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-98, "familyName" : "LIPASE", "score" : 331.3, "model-ac" : "PTHR11005" }, { "signature" : { "accession" : "SSF53474", "name" : "alpha/beta-Hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 411, "hmmLength" : 377, "location-fragments" : [ { "start" : 50, "end" : 411, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.36E-53, "model-ac" : "0047764" } ], "xref" : [ { "name" : "XP_018910104.1 PREDICTED: lipase 3-like [Bemisia tabaci]", "id" : "XP_018910104.1" } ] },{ "sequence" : "MLHSCELASPAHFELSLAKEIQLTKSRGDFLVLHLSDLVRLSFMAATSDCDPLRLEGLRLLYDVITKFAKVPEPEFPGHLLLEQFQAQVTW", "md5" : "d51f0f39e1b979fc7dfd4f5e40ed2e16", "matches" : [ { "signature" : { "accession" : "PTHR21663", "name" : "HYPOTHETICAL HEAT DOMAIN-CONTAINING", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR040108", "name" : "Laa1/Sip1/HEATR5", "description" : "Laa1/Sip1/HEATR5", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 90, "hmmStart" : 1217, "hmmEnd" : 1303, "hmmLength" : 1947, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 91, "location-fragments" : [ { "start" : 2, "end" : 90, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-39, "familyName" : "HYPOTHETICAL HEAT DOMAIN-CONTAINING", "score" : 135.6, "model-ac" : "PTHR21663" } ], "xref" : [ { "name" : "XP_018910490.1 PREDICTED: HEAT repeat-containing protein 5A-like [Bemisia tabaci]", "id" : "XP_018910490.1" } ] },{ "sequence" : "MSFLKGSMRERGQKSNLAEEDTSDVIGIENDETQFSDSEETEFPENFESNDGPVPPIVPTTSSAPPPVATVSTTPSTSASAAGKNDSLAPTSQKKEKTKTPPIKQTASSQVLQAYLASKKKPEDDHLSKFFAAMEATVRKMKPIFQIKVKAQVSSIIADFEMQSLLSEEASNHAVPSTHTTTRSNFFAQYPPVPPSPSITPSSSVISVNSCSSVNSLSDIARNISPVRPVDFSITQGQIITPDSGQVFQFSSRERSQSTLEGDFLSESQETGHSFLRL", "md5" : "f06ede609bd90c4cfcfd242bff536415", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 106, "location-fragments" : [ { "start" : 1, "end" : 106, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 64, "end" : 89, "location-fragments" : [ { "start" : 64, "end" : 89, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910443.1 PREDICTED: uncharacterized protein LOC109039428 [Bemisia tabaci]", "id" : "XP_018910443.1" } ] },{ "sequence" : "MMRITKTPLVPLKPTLKKIPDEDPLRLYIDRFQKWADATEYQLFYRNGTRVWVPHPDFVWESALVVADYKEKVLEVSLENSKELKNIPISSDADLPPLCNPDILIGQNDLTSLSYLHEPAVLYNLQVRFVDKCAIYTYCGIVLVAINPYSELPIYGSDTIWAYRGQAMGDLEPHIFAVAEEAYTKMEREKQDQSIIVSGESGAGKTVSAKYAMRYFATVGGSTTETQIEKKVLASSPIMEAIGNAKTIRNDNSSRFGKFIELQFSKNYNINGASMRTYLLEKSRVVFQAAEERNYHIFYQLCASRSRYPHLKLDQAKQFMYLNQEDSIAGIDDEVCFNDTLSAFTTLGFSEADINDMLKILASILHLGNISILQGSHVGDRGDADSSYISEKDFHLKTLTELLDLDIQELMKWLCHRRIISMRETFDKDMNMNEAMGARDALAKHIYAQLFAWIVSQINRSLESSDAKYKFIGVLDIYGFETFETNSFEQFCINYANEKLQQQFNQHVFKLEQEEYLKEEIEWKFIDFYDNQPCIDLIEIKLGILDLLDEECRMPKGTDASWADKLYNKCEKWQHFSKPRFGTKTFSIKHFADLVEYDTAGFLEKNKDTVIEEQVNVLRSSRNQLLRHLFVESEKKLAPQYAATIGHSGRTKVAVLPQKSPSATLGSSAKQHKKTVGSQFRDSLNALMVTLNATTPHYIRCIKPNDFKQPFEYNPVRAVQQLRACGVLETIRISAAGFPSRWTYFDFMKRYRVLCSAKDIDRNDMKKTCERTLQKCIKNQEKYKFGKSKIFFRAGQVAYLEKLRADKLKHCCIIIQKTVRGYLAKRRYQRIKSSTLTIQRVVRGFLARRRVHRIRQLKSAIIIQKRVRGWLQRTKYLRLRRTAFGLQRYGRGLLARRKFLELKYNKAALVIQKRVRGWLAKKKYKEDLQKIVICQSAIRRFLARRRYKKLKREARSVEHIKKLNKGLENKIISMQQRIGELTKENTSLKTASQEKNEMLVKLDSLKGADSELKKLKNVLNEKEIELSAIRAELSREKSEKMDLLNDYERDKTKLLNDTNKLRSENEQLKEKLSIVMDEMTESKVNLEEIIRTRIEHERQILIREQDQDREAYQKLLSEKNMLESRLEALEKEGNKTGNLDSFSSHNRSLSDASTVSVCDPESSASNMSDHSEEKTDLQLVLKLQQKVKSLEAERAKLHKRIEESENLSSPESRASYKDAIKAADLEIENEKLKADLTQLRQCIAENCDSANIGEIAVQELLSQFSSLQSELTRKRDECLQLRGVLLNNTESIKSVATSNYSTKRDVDIINEDGELAIAFEAQKKINRQLEREIESEKAKWSQKYEDLVQETKKLREENERQQKLLSVNLNKTPQSQTESIMQHEITRLTSENLDLQEKVDHLQEEIRRLKRQLSRVGNPPEDEPAVNGNNVKVENGEHGNNLPLIRKKERNYLGMIEYQKGDEDVIMRHLIIELKPKVAVTLLPGLPAYILFMCIRHTDYINDDEKVRALLTAFINQVKKVIKRQANKQRQQDNHSNHSFEVTILWLSNTLRLLNNLKQYSGDKAFQEHNTKTQNAQCLLNFDLSEYRQVLSDIAVWIYQSVINYMEEKIQQLAITAVLEYESIMSQPTRSKSTSSADSSPTLSPPSALQEQLSTYHAILCAHGVDSFVINQAFKQLFYFICASCMNTLLLRKDLCNWAKGMQIRFNISHLEQWCRDQKLLDSSEILDTLLPIVQAAQLLQARKTKDDVESICEMCSKMTPNQIIKLLNLYTPADEFEGKISVQFIRSVQEILSQRPKDAGQPLLLMDTKHNFPVRFPFSPSTIRLEHIEIPECLNLSMLKKV", "md5" : "97e125f0ee539c1c971b115ef93fb962", "matches" : [ { "signature" : { "accession" : "G3DSA:1.20.58.530", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 480, "end" : 693, "hmmStart" : 1, "hmmEnd" : 646, "hmmLength" : 160, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-237, "score" : 791.7, "envelopeStart" : 52, "envelopeEnd" : 735, "postProcessed" : true, "location-fragments" : [ { "start" : 667, "end" : 693, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 480, "end" : 608, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.0E-237, "score" : 792.5, "model-ac" : "1vomA04" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1180, "end" : 1207, "location-fragments" : [ { "start" : 1180, "end" : 1207, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PS51456", "name" : "MYOSIN_MOTOR", "description" : "Myosin motor domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001609", "name" : "Myosin_head_motor_dom", "description" : "Myosin head, motor domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "motor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003774" }, { "name" : "myosin complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016459" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 105, "end" : 805, "score" : 251.028, "alignment" : "IGQNDLTSLSYLHEPAVLYNLQVRFVDKCaIYTYCGIVLVAINPYSELPIYGSDTIWAYRGQAMGDLEPHIFAVAEEAYTKMEREKQDQSIIVSGESGAGKTVSAKYAMRYFATVGGSTTE-TQIEKKVLASSPIMEAIGNAKTIRNDNSSRFGKFIELQFSKNYNINGASMRTYLLEKSRVVFQAAEERNYHIFYQLCASRSRY--PHLKLDQAKQFMYLN--QEDSIAGIDDEVCFNDTLSAFTTLGFSEADINDMLKILASILHLGNISILQGSHvgdrgdaDSSYISEKDFHLKTLTELLDLDIQELMKWLCHRRIISMRETFDKDMNMNEAMGARDALAKHIYAQLFAWIVSQINRSLESSDAKYKFIGVLDIYGFETFETNSFEQFCINYANEKLQQQFNQHVFKLEQEEYLKEEIEWKFIDFYDNQPCIDLIEI-KLGILDLLDEECRMPKGTDASWADKLYNKCEKWQHFSKPRFG-TKTFSIKHFADLVEYDTAGFLEKNKDTVIEEQVNVLRSSRNQLLRHLFVESEKKLAPQyaatighsgrtkvavlpqkspsaTLGSSAKQHKKTVGSQFRDSLNALMVTLNATTPHYIRCIKPNDFKQPFEYNPVRAVQQLRACGVLETIRISAAGFPSRWTYFDFMKRYRVLCSAK--DIDRNDMKKTCERTLQKCIKNQEKYKFGKSKIFFRAGQVAYLEKLRA", "location-fragments" : [ { "start" : 105, "end" : 805, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51456" }, { "signature" : { "accession" : "PTHR13140:SF356", "name" : "UNCONVENTIONAL MYOSIN-VB", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 44, "end" : 1236, "hmmStart" : 6, "hmmEnd" : 1203, "hmmLength" : 1849, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 39, "envelopeEnd" : 1284, "location-fragments" : [ { "start" : 44, "end" : 1236, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1325, "end" : 1842, "hmmStart" : 1340, "hmmEnd" : 1848, "hmmLength" : 1849, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1311, "envelopeEnd" : 1843, "location-fragments" : [ { "start" : 1325, "end" : 1842, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "UNCONVENTIONAL MYOSIN-VB", "score" : 1821.4, "model-ac" : "PTHR13140:SF356" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 903, "end" : 956, "hmmLength" : 784, "location-fragments" : [ { "start" : 903, "end" : 956, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.08E-7, "model-ac" : "0035392" }, { "signature" : { "accession" : "SSF50084", "name" : "Myosin S1 fragment, N-terminal domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR008989", "name" : "Myosin_S1_N", "description" : "Myosin S1 fragment, N-terminal", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "motor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003774" }, { "name" : "actin filament binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0051015" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 98, "hmmLength" : 58, "location-fragments" : [ { "start" : 44, "end" : 98, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.41E-9, "model-ac" : "0048548" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1112, "end" : 1132, "location-fragments" : [ { "start" : 1112, "end" : 1132, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 950, "end" : 984, "location-fragments" : [ { "start" : 950, "end" : 984, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1319, "end" : 1364, "location-fragments" : [ { "start" : 1319, "end" : 1364, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1213, "end" : 1242, "location-fragments" : [ { "start" : 1213, "end" : 1242, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1385, "end" : 1412, "location-fragments" : [ { "start" : 1385, "end" : 1412, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "G3DSA:3.40.850.10", "name" : "Kinesin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036961", "name" : "Kinesin_motor_dom_sf", "description" : "Kinesin motor domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 100, "end" : 734, "hmmStart" : 1, "hmmEnd" : 646, "hmmLength" : 345, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-237, "score" : 791.7, "envelopeStart" : 52, "envelopeEnd" : 735, "postProcessed" : true, "location-fragments" : [ { "start" : 100, "end" : 348, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 694, "end" : 734, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 464, "end" : 479, "dc-status" : "NC_TERMINAL_DISC" } ] } ], "evalue" : 1.0E-237, "score" : 792.5, "model-ac" : "1vomA01" }, { "signature" : { "accession" : "cd15470", "name" : "Myo5_CBD", "description" : "Myo5_CBD", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1461, "end" : 1836, "sites" : [ ], "evalue" : 3.20878E-168, "score" : 512.142, "location-fragments" : [ { "start" : 1461, "end" : 1836, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd15470" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 851, "end" : 903, "hmmLength" : 784, "location-fragments" : [ { "start" : 851, "end" : 903, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.25E-5, "model-ac" : "0035392" }, { "signature" : { "accession" : "PS50096", "name" : "IQ", "description" : "IQ motif profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000048", "name" : "IQ_motif_EF-hand-BS", "description" : "IQ motif, EF-hand binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 831, "end" : 860, "score" : 8.535, "alignment" : "IKSSTLTIQRVVRGFLARRRVHRIRQLKSA", "location-fragments" : [ { "start" : 831, "end" : 860, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50096" }, { "signature" : { "accession" : "PS50096", "name" : "IQ", "description" : "IQ motif profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000048", "name" : "IQ_motif_EF-hand-BS", "description" : "IQ motif, EF-hand binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 856, "end" : 882, "score" : 8.297, "alignment" : "QLKSAIIIQKRVRGWLQRTKYLRLRRT---", "location-fragments" : [ { "start" : 856, "end" : 882, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50096" }, { "signature" : { "accession" : "PS50096", "name" : "IQ", "description" : "IQ motif profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000048", "name" : "IQ_motif_EF-hand-BS", "description" : "IQ motif, EF-hand binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 904, "end" : 931, "score" : 9.505, "alignment" : "YNKAALVIQKRVRGWLAKKKYKEDLQKI--", "location-fragments" : [ { "start" : 904, "end" : 931, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50096" }, { "signature" : { "accession" : "PS51126", "name" : "DILUTE", "description" : "Dilute domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002710", "name" : "Dilute_dom", "description" : "Dilute domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1512, "end" : 1795, "score" : 46.488, "alignment" : "TAFINQVKKVIkrqankqrqqdNHSNHSFEVTILWLSNTLRLLNNLKQYSGDKAFQEHNTKTQNAQCLLNFDLSEYRQVLSDIAVWIYQSVINYMEEKIQQLAITAVLEYESI----MSQPTRSKSTSSADSSPTLSPPSALQEQLSTYHAILCAHGVDSFVINQAFKQLFYFICASCMNTLLLRKDLCNWAKGMQIRFNISHLEQWCRDQKLLdSSEILDTLLPIVQAAQLLQARK-TKDDVESICEMCSKMTPNQIIKLLNLyTPADEFEGKISVQFIRSVQEILSQ", "location-fragments" : [ { "start" : 1512, "end" : 1795, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51126" }, { "signature" : { "accession" : "PS50096", "name" : "IQ", "description" : "IQ motif profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000048", "name" : "IQ_motif_EF-hand-BS", "description" : "IQ motif, EF-hand binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 808, "end" : 837, "score" : 8.608, "alignment" : "LKHCCIIIQKTVRGYLAKRRYQRIKSSTLT", "location-fragments" : [ { "start" : 808, "end" : 837, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50096" }, { "signature" : { "accession" : "PTHR13140", "name" : "MYOSIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 44, "end" : 1236, "hmmStart" : 6, "hmmEnd" : 1203, "hmmLength" : 1849, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 39, "envelopeEnd" : 1284, "location-fragments" : [ { "start" : 44, "end" : 1236, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1325, "end" : 1842, "hmmStart" : 1340, "hmmEnd" : 1848, "hmmLength" : 1849, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1311, "envelopeEnd" : 1843, "location-fragments" : [ { "start" : 1325, "end" : 1842, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "UNCONVENTIONAL MYOSIN-VB", "score" : 1821.4, "model-ac" : "PTHR13140" }, { "signature" : { "accession" : "PF00063", "name" : "Myosin_head", "description" : "Myosin head (motor domain)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001609", "name" : "Myosin_head_motor_dom", "description" : "Myosin head, motor domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "motor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003774" }, { "name" : "myosin complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016459" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 108, "end" : 793, "hmmStart" : 2, "hmmEnd" : 677, "hmmLength" : 677, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.8E-260, "score" : 865.9, "envelopeStart" : 107, "envelopeEnd" : 793, "postProcessed" : true, "location-fragments" : [ { "start" : 108, "end" : 793, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-260, "score" : 865.9, "model-ac" : "PF00063" }, { "signature" : { "accession" : "SM00242", "name" : "MYSc_2a", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001609", "name" : "Myosin_head_motor_dom", "description" : "Myosin head, motor domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "motor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003774" }, { "name" : "myosin complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016459" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 99, "end" : 806, "hmmStart" : 1, "hmmEnd" : 771, "hmmLength" : 771, "hmmBounds" : "COMPLETE", "evalue" : 0.0, "score" : 1251.7, "location-fragments" : [ { "start" : 99, "end" : 806, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "score" : 1251.7, "model-ac" : "SM00242" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1257, "end" : 1277, "location-fragments" : [ { "start" : 1257, "end" : 1277, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "SM01132", "name" : "DIL_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002710", "name" : "Dilute_dom", "description" : "Dilute domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1672, "end" : 1777, "hmmStart" : 1, "hmmEnd" : 122, "hmmLength" : 122, "hmmBounds" : "COMPLETE", "evalue" : 5.2E-44, "score" : 162.2, "location-fragments" : [ { "start" : 1672, "end" : 1777, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.2E-44, "score" : 162.2, "model-ac" : "SM01132" }, { "signature" : { "accession" : "G3DSA:1.20.5.190", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 906, "end" : 957, "hmmStart" : 3, "hmmEnd" : 53, "hmmLength" : 58, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.9E-10, "score" : 40.2, "envelopeStart" : 902, "envelopeEnd" : 957, "postProcessed" : true, "location-fragments" : [ { "start" : 906, "end" : 957, "dc-status" : "CONTINUOUS" } ] }, { "start" : 806, "end" : 857, "hmmStart" : 1, "hmmEnd" : 55, "hmmLength" : 58, "hmmBounds" : "INCOMPLETE", "evalue" : 3.3E-17, "score" : 63.9, "envelopeStart" : 805, "envelopeEnd" : 860, "postProcessed" : true, "location-fragments" : [ { "start" : 806, "end" : 857, "dc-status" : "CONTINUOUS" } ] }, { "start" : 858, "end" : 905, "hmmStart" : 6, "hmmEnd" : 56, "hmmLength" : 58, "hmmBounds" : "INCOMPLETE", "evalue" : 7.2E-15, "score" : 56.4, "envelopeStart" : 855, "envelopeEnd" : 909, "postProcessed" : true, "location-fragments" : [ { "start" : 858, "end" : 905, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-40, "score" : 137.5, "model-ac" : "2ix7C00" }, { "signature" : { "accession" : "G3DSA:1.20.120.720", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 349, "end" : 666, "hmmStart" : 1, "hmmEnd" : 646, "hmmLength" : 647, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-237, "score" : 791.7, "envelopeStart" : 52, "envelopeEnd" : 735, "postProcessed" : true, "location-fragments" : [ { "start" : 349, "end" : 463, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 666, "end" : 666, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 609, "end" : 637, "dc-status" : "NC_TERMINAL_DISC" } ] } ], "evalue" : 1.0E-237, "score" : 792.5, "model-ac" : "1vomA03" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1127, "end" : 1146, "location-fragments" : [ { "start" : 1127, "end" : 1146, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:2.30.30.360", "name" : "Myosin S1 fragment", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR008989", "name" : "Myosin_S1_N", "description" : "Myosin S1 fragment, N-terminal", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "motor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003774" }, { "name" : "actin filament binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0051015" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 54, "end" : 99, "hmmStart" : 1, "hmmEnd" : 646, "hmmLength" : 647, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-237, "score" : 791.7, "envelopeStart" : 52, "envelopeEnd" : 735, "postProcessed" : true, "location-fragments" : [ { "start" : 54, "end" : 99, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-237, "score" : 792.5, "model-ac" : "1vomA02" }, { "signature" : { "accession" : "PR00193", "name" : "MYOSINHEAVY", "description" : "Myosin heavy chain signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001609", "name" : "Myosin_head_motor_dom", "description" : "Myosin head, motor domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "motor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003774" }, { "name" : "myosin complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016459" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 237, "end" : 264, "pvalue" : 1.0E-16, "score" : 72.4, "motifNumber" : 3, "location-fragments" : [ { "start" : 237, "end" : 264, "dc-status" : "CONTINUOUS" } ] }, { "start" : 524, "end" : 552, "pvalue" : 8.28E-12, "score" : 40.63, "motifNumber" : 5, "location-fragments" : [ { "start" : 524, "end" : 552, "dc-status" : "CONTINUOUS" } ] }, { "start" : 192, "end" : 217, "pvalue" : 1.94E-14, "score" : 60.35, "motifNumber" : 2, "location-fragments" : [ { "start" : 192, "end" : 217, "dc-status" : "CONTINUOUS" } ] }, { "start" : 136, "end" : 155, "pvalue" : 1.73E-11, "score" : 58.05, "motifNumber" : 1, "location-fragments" : [ { "start" : 136, "end" : 155, "dc-status" : "CONTINUOUS" } ] }, { "start" : 471, "end" : 499, "pvalue" : 1.0E-16, "score" : 76.77, "motifNumber" : 4, "location-fragments" : [ { "start" : 471, "end" : 499, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-62, "graphscan" : "IIIII", "model-ac" : "PR00193" }, { "signature" : { "accession" : "SM00015", "name" : "iq_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000048", "name" : "IQ_motif_EF-hand-BS", "description" : "IQ motif, EF-hand binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 878, "end" : 900, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 26.0, "score" : 10.3, "location-fragments" : [ { "start" : 878, "end" : 900, "dc-status" : "CONTINUOUS" } ] }, { "start" : 807, "end" : 829, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 4.8E-5, "score" : 32.8, "location-fragments" : [ { "start" : 807, "end" : 829, "dc-status" : "CONTINUOUS" } ] }, { "start" : 926, "end" : 948, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.073, "score" : 22.2, "location-fragments" : [ { "start" : 926, "end" : 948, "dc-status" : "CONTINUOUS" } ] }, { "start" : 855, "end" : 877, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 3.3E-4, "score" : 30.0, "location-fragments" : [ { "start" : 855, "end" : 877, "dc-status" : "CONTINUOUS" } ] }, { "start" : 903, "end" : 925, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-4, "score" : 30.9, "location-fragments" : [ { "start" : 903, "end" : 925, "dc-status" : "CONTINUOUS" } ] }, { "start" : 830, "end" : 852, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.002, "score" : 27.4, "location-fragments" : [ { "start" : 830, "end" : 852, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-41, "score" : 153.5, "model-ac" : "SM00015" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1153, "end" : 1173, "location-fragments" : [ { "start" : 1153, "end" : 1173, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00612", "name" : "IQ", "description" : "IQ calmodulin-binding motif", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000048", "name" : "IQ_motif_EF-hand-BS", "description" : "IQ motif, EF-hand binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 810, "end" : 829, "hmmStart" : 2, "hmmEnd" : 21, "hmmLength" : 21, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 0.0017, "score" : 18.0, "envelopeStart" : 809, "envelopeEnd" : 829, "postProcessed" : true, "location-fragments" : [ { "start" : 810, "end" : 829, "dc-status" : "CONTINUOUS" } ] }, { "start" : 930, "end" : 948, "hmmStart" : 3, "hmmEnd" : 21, "hmmLength" : 21, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 0.013, "score" : 15.2, "envelopeStart" : 928, "envelopeEnd" : 948, "postProcessed" : true, "location-fragments" : [ { "start" : 930, "end" : 948, "dc-status" : "CONTINUOUS" } ] }, { "start" : 833, "end" : 851, "hmmStart" : 2, "hmmEnd" : 20, "hmmLength" : 21, "hmmBounds" : "INCOMPLETE", "evalue" : 0.0014, "score" : 18.2, "envelopeStart" : 832, "envelopeEnd" : 852, "postProcessed" : true, "location-fragments" : [ { "start" : 833, "end" : 851, "dc-status" : "CONTINUOUS" } ] }, { "start" : 858, "end" : 876, "hmmStart" : 2, "hmmEnd" : 20, "hmmLength" : 21, "hmmBounds" : "INCOMPLETE", "evalue" : 1.4E-4, "score" : 21.3, "envelopeStart" : 857, "envelopeEnd" : 877, "postProcessed" : true, "location-fragments" : [ { "start" : 858, "end" : 876, "dc-status" : "CONTINUOUS" } ] }, { "start" : 906, "end" : 925, "hmmStart" : 2, "hmmEnd" : 21, "hmmLength" : 21, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.8E-5, "score" : 23.1, "envelopeStart" : 905, "envelopeEnd" : 925, "postProcessed" : true, "location-fragments" : [ { "start" : 906, "end" : 925, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-23, "score" : 78.2, "model-ac" : "PF00612" }, { "signature" : { "accession" : "PS50096", "name" : "IQ", "description" : "IQ motif profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000048", "name" : "IQ_motif_EF-hand-BS", "description" : "IQ motif, EF-hand binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 929, "end" : 956, "score" : 7.748, "alignment" : "--QKIVICQSAIRRFLARRRYKKLKREARS", "location-fragments" : [ { "start" : 929, "end" : 956, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50096" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 87, "end" : 856, "hmmLength" : 784, "location-fragments" : [ { "start" : 87, "end" : 856, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.89E-270, "model-ac" : "0035392" }, { "signature" : { "accession" : "G3DSA:3.30.70.3240", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 737, "end" : 805, "hmmStart" : 1, "hmmEnd" : 68, "hmmLength" : 72, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.0E-24, "score" : 87.6, "envelopeStart" : 737, "envelopeEnd" : 806, "postProcessed" : true, "location-fragments" : [ { "start" : 737, "end" : 805, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-24, "score" : 87.6, "model-ac" : "1vomA05" }, { "signature" : { "accession" : "cd01380", "name" : "MYSc_Myo5", "description" : "MYSc_Myo5", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR036103", "name" : "MYSc_Myo5", "description" : "Class V myosin, motor domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 119, "end" : 793, "sites" : [ { "description" : "converter subdomain", "numLocations" : 27, "siteLocations" : [ { "start" : 751, "end" : 751, "residue" : "Y" }, { "start" : 783, "end" : 783, "residue" : "Y" }, { "start" : 756, "end" : 756, "residue" : "S" }, { "start" : 786, "end" : 786, "residue" : "G" }, { "start" : 788, "end" : 788, "residue" : "S" }, { "start" : 779, "end" : 779, "residue" : "N" }, { "start" : 780, "end" : 780, "residue" : "Q" }, { "start" : 748, "end" : 748, "residue" : "M" }, { "start" : 790, "end" : 790, "residue" : "I" }, { "start" : 757, "end" : 757, "residue" : "A" }, { "start" : 778, "end" : 778, "residue" : "K" }, { "start" : 754, "end" : 754, "residue" : "L" }, { "start" : 755, "end" : 755, "residue" : "C" }, { "start" : 789, "end" : 789, "residue" : "K" }, { "start" : 750, "end" : 750, "residue" : "R" }, { "start" : 791, "end" : 791, "residue" : "F" }, { "start" : 793, "end" : 793, "residue" : "R" }, { "start" : 787, "end" : 787, "residue" : "K" }, { "start" : 781, "end" : 781, "residue" : "E" }, { "start" : 747, "end" : 747, "residue" : "F" }, { "start" : 752, "end" : 752, "residue" : "R" }, { "start" : 753, "end" : 753, "residue" : "V" }, { "start" : 749, "end" : 749, "residue" : "K" }, { "start" : 792, "end" : 792, "residue" : "F" }, { "start" : 785, "end" : 785, "residue" : "F" }, { "start" : 784, "end" : 784, "residue" : "K" }, { "start" : 782, "end" : 782, "residue" : "K" } ] }, { "description" : "P-loop", "numLocations" : 8, "siteLocations" : [ { "start" : 203, "end" : 203, "residue" : "A" }, { "start" : 204, "end" : 204, "residue" : "G" }, { "start" : 206, "end" : 206, "residue" : "T" }, { "start" : 201, "end" : 201, "residue" : "S" }, { "start" : 202, "end" : 202, "residue" : "G" }, { "start" : 199, "end" : 199, "residue" : "G" }, { "start" : 205, "end" : 205, "residue" : "K" }, { "start" : 200, "end" : 200, "residue" : "E" } ] }, { "description" : "relay loop", "numLocations" : 22, "siteLocations" : [ { "start" : 516, "end" : 516, "residue" : "Y" }, { "start" : 511, "end" : 511, "residue" : "L" }, { "start" : 508, "end" : 508, "residue" : "V" }, { "start" : 519, "end" : 519, "residue" : "E" }, { "start" : 509, "end" : 509, "residue" : "F" }, { "start" : 525, "end" : 525, "residue" : "F" }, { "start" : 505, "end" : 505, "residue" : "N" }, { "start" : 522, "end" : 522, "residue" : "E" }, { "start" : 524, "end" : 524, "residue" : "K" }, { "start" : 512, "end" : 512, "residue" : "E" }, { "start" : 513, "end" : 513, "residue" : "Q" }, { "start" : 510, "end" : 510, "residue" : "K" }, { "start" : 527, "end" : 527, "residue" : "D" }, { "start" : 514, "end" : 514, "residue" : "E" }, { "start" : 506, "end" : 506, "residue" : "Q" }, { "start" : 523, "end" : 523, "residue" : "W" }, { "start" : 526, "end" : 526, "residue" : "I" }, { "start" : 515, "end" : 515, "residue" : "E" }, { "start" : 507, "end" : 507, "residue" : "H" }, { "start" : 521, "end" : 521, "residue" : "I" }, { "start" : 528, "end" : 528, "residue" : "F" }, { "start" : 520, "end" : 520, "residue" : "E" } ] }, { "description" : "ATP binding site", "numLocations" : 34, "siteLocations" : [ { "start" : 203, "end" : 203, "residue" : "A" }, { "start" : 481, "end" : 481, "residue" : "E" }, { "start" : 254, "end" : 254, "residue" : "S" }, { "start" : 201, "end" : 201, "residue" : "S" }, { "start" : 151, "end" : 151, "residue" : "E" }, { "start" : 199, "end" : 199, "residue" : "G" }, { "start" : 153, "end" : 153, "residue" : "P" }, { "start" : 255, "end" : 255, "residue" : "R" }, { "start" : 253, "end" : 253, "residue" : "S" }, { "start" : 245, "end" : 245, "residue" : "A" }, { "start" : 150, "end" : 150, "residue" : "S" }, { "start" : 251, "end" : 251, "residue" : "D" }, { "start" : 476, "end" : 476, "residue" : "D" }, { "start" : 202, "end" : 202, "residue" : "G" }, { "start" : 154, "end" : 154, "residue" : "I" }, { "start" : 249, "end" : 249, "residue" : "R" }, { "start" : 479, "end" : 479, "residue" : "G" }, { "start" : 155, "end" : 155, "residue" : "Y" }, { "start" : 248, "end" : 248, "residue" : "I" }, { "start" : 480, "end" : 480, "residue" : "F" }, { "start" : 204, "end" : 204, "residue" : "G" }, { "start" : 250, "end" : 250, "residue" : "N" }, { "start" : 477, "end" : 477, "residue" : "I" }, { "start" : 149, "end" : 149, "residue" : "Y" }, { "start" : 205, "end" : 205, "residue" : "K" }, { "start" : 246, "end" : 246, "residue" : "K" }, { "start" : 148, "end" : 148, "residue" : "P" }, { "start" : 478, "end" : 478, "residue" : "Y" }, { "start" : 206, "end" : 206, "residue" : "T" }, { "start" : 147, "end" : 147, "residue" : "N" }, { "start" : 152, "end" : 152, "residue" : "L" }, { "start" : 247, "end" : 247, "residue" : "T" }, { "start" : 252, "end" : 252, "residue" : "N" }, { "start" : 200, "end" : 200, "residue" : "E" } ] }, { "description" : "putative phosphorylation site", "numLocations" : 1, "siteLocations" : [ { "start" : 424, "end" : 424, "residue" : "E" } ] }, { "description" : "purine-binding loop", "numLocations" : 9, "siteLocations" : [ { "start" : 150, "end" : 150, "residue" : "S" }, { "start" : 147, "end" : 147, "residue" : "N" }, { "start" : 152, "end" : 152, "residue" : "L" }, { "start" : 151, "end" : 151, "residue" : "E" }, { "start" : 149, "end" : 149, "residue" : "Y" }, { "start" : 154, "end" : 154, "residue" : "I" }, { "start" : 153, "end" : 153, "residue" : "P" }, { "start" : 155, "end" : 155, "residue" : "Y" }, { "start" : 148, "end" : 148, "residue" : "P" } ] }, { "description" : "switch II region", "numLocations" : 9, "siteLocations" : [ { "start" : 481, "end" : 481, "residue" : "E" }, { "start" : 476, "end" : 476, "residue" : "D" }, { "start" : 477, "end" : 477, "residue" : "I" }, { "start" : 479, "end" : 479, "residue" : "G" }, { "start" : 484, "end" : 484, "residue" : "E" }, { "start" : 482, "end" : 482, "residue" : "T" }, { "start" : 478, "end" : 478, "residue" : "Y" }, { "start" : 483, "end" : 483, "residue" : "F" }, { "start" : 480, "end" : 480, "residue" : "F" } ] }, { "description" : "SH1 helix", "numLocations" : 11, "siteLocations" : [ { "start" : 729, "end" : 729, "residue" : "E" }, { "start" : 734, "end" : 734, "residue" : "S" }, { "start" : 736, "end" : 736, "residue" : "A" }, { "start" : 733, "end" : 733, "residue" : "I" }, { "start" : 727, "end" : 727, "residue" : "V" }, { "start" : 728, "end" : 728, "residue" : "L" }, { "start" : 732, "end" : 732, "residue" : "R" }, { "start" : 735, "end" : 735, "residue" : "A" }, { "start" : 731, "end" : 731, "residue" : "I" }, { "start" : 730, "end" : 730, "residue" : "T" }, { "start" : 726, "end" : 726, "residue" : "G" } ] }, { "description" : "switch I region", "numLocations" : 11, "siteLocations" : [ { "start" : 250, "end" : 250, "residue" : "N" }, { "start" : 251, "end" : 251, "residue" : "D" }, { "start" : 254, "end" : 254, "residue" : "S" }, { "start" : 249, "end" : 249, "residue" : "R" }, { "start" : 246, "end" : 246, "residue" : "K" }, { "start" : 247, "end" : 247, "residue" : "T" }, { "start" : 248, "end" : 248, "residue" : "I" }, { "start" : 255, "end" : 255, "residue" : "R" }, { "start" : 253, "end" : 253, "residue" : "S" }, { "start" : 245, "end" : 245, "residue" : "A" }, { "start" : 252, "end" : 252, "residue" : "N" } ] } ], "evalue" : 0.0, "score" : 1191.58, "location-fragments" : [ { "start" : 119, "end" : 793, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01380" }, { "signature" : { "accession" : "PF01843", "name" : "DIL", "description" : "DIL domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002710", "name" : "Dilute_dom", "description" : "Dilute domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1672, "end" : 1774, "hmmStart" : 1, "hmmEnd" : 103, "hmmLength" : 104, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.2E-31, "score" : 109.0, "envelopeStart" : 1672, "envelopeEnd" : 1775, "postProcessed" : true, "location-fragments" : [ { "start" : 1672, "end" : 1774, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-31, "score" : 109.0, "model-ac" : "PF01843" }, { "signature" : { "accession" : "PS50096", "name" : "IQ", "description" : "IQ motif profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000048", "name" : "IQ_motif_EF-hand-BS", "description" : "IQ motif, EF-hand binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 879, "end" : 908, "score" : 7.419, "alignment" : "LRRTAFGLQRYGRGLLARRKFLELKYNKAA", "location-fragments" : [ { "start" : 879, "end" : 908, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50096" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 988, "end" : 1078, "location-fragments" : [ { "start" : 988, "end" : 1078, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" } ], "xref" : [ { "name" : "XP_018910252.1 PREDICTED: unconventional myosin-Va isoform X1 [Bemisia tabaci]", "id" : "XP_018910252.1" } ] },{ "sequence" : "MVNLETCFICGLNLAEGEVDAVKSRGLKTLIRCSAECKDGNDAFLKTIKSVKVHSKCRKIYTKEKSRRVKSTQPESTSASFRSNVPSFDFKKNCIFCAEDASDVFLQRQIKVKRSKRVSVNRVETMGIKDTLMEIIDERDDEQCQQLFTRISTVDLIAAEARYHSNCCKLFYSQPRKGKPRGRPESAHTGAAMNFAFNFLEKNSEECQFSLDEIFEGFKGELPSQRVIKEKLVAKYGEDIQVTSVKNRKPVVCFRNTGHKILSEQWYSKQDASEKDERLRIVKSAAEIICEDIRQTVYDTENYPQCNDFLISVEEDVPETLNCLLETIITSHKKGSMDKWKTRCTAIAHAIIASVRPKSFVSGLQVGLSSLINQKFGSRQLIDVLASLGFCSTYREATRLQISAMTDPPNFSIQESFSQFVFDNADVNVCTLDGYNTFHSMGGIQCITPRTAVSCEKKIPRLKIIPSADSVALSSQVPIQIFHKTENSGLNLVKIENLCDKNPLCEEIVPSISDFLWLFAKASESFELPGWNGYMEKITAHLPHEKSYILCLPFTNAPPSDFNTIYTVLLTAVEKTKLAKQTCCIVTFDQPLYFKARDIIASAEKGSDLSKIIVRLGGFHLLMSYLGALGFIMDGSGLKDVFNTVYAGASTDKMLTGHAYARAFRAHLLTRLALAKIIFKELNLTSDEETLLTEYLLMLEEPDYLSKIQNTEVRSLIDKFLLLLRQIEERGPTSKLWVQYFDAVTLMILFVESERSGNWTLHLQTVQKMIPFFHASGHFLYAKSCHLYLQDMLELKNKMSLGEYCSFVERGMFTVRRSNKFWSGIWSDMTIEQTLMRSLKSSGGLSHGRGISDSTLAKWILSMPFLSSISQSVENFCKISLHTTEQHVDSRPSRVSRDNNDCGKFTEWFSLHPPFPENDNLVSISTGVVADPKINCHKAREVGRVQMSTLEGTFGEIKFKRSNRVLPISATNCSVKLNNKVIPINPTLLFQRISFLKKSDKQLEDYFQFELAPYPLALFDESGMRKTSKSVIYEFFSTCETVVKLKDSICVIDGGFLVHKIIWHRQETYSQILDKHVEYVQKNYSANTTVVFDGYPEDSEAKSTKTAERCRRSKSLSSPEIIFEESMSATVTQSKFLANEKNKSRLIALLRERFERAGIKTKQAKEDADVLIVNTAMEYSENSPSVVIVGEDSDLLVILTALNNSKKNIYFLKPGKGKIPNKTYSLNQNLTLADNVSLLHAFTGCDTTSAIFRQGKHKLFKLLQKDESLKLAAQIFKKPNASPEAVASAGEKLFLSLYGAQGDVSLNQFRYQCFTQAISKSAPNNLASLPPSSDSARMHSFRVYLQMQMWYGHEISPLQWGWKHCKTGLFPIPMQNDPAPQELLKLISCKCVKGCQNACSCRKAGLHCSLLCKNCEGRSCSNVADIIEDEDSMDEDEM", "md5" : "c2abe45e027bf1e53d4a6aad72799dc2", "matches" : [ { "signature" : { "accession" : "PTHR46704:SF4", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 51, "end" : 1396, "hmmStart" : 17, "hmmEnd" : 1070, "hmmLength" : 1074, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 36, "envelopeEnd" : 1404, "location-fragments" : [ { "start" : 51, "end" : 1396, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-121, "familyName" : "", "score" : 409.1, "model-ac" : "PTHR46704:SF4" }, { "signature" : { "accession" : "PTHR46704", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 51, "end" : 1396, "hmmStart" : 17, "hmmEnd" : 1070, "hmmLength" : 1074, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 36, "envelopeEnd" : 1404, "location-fragments" : [ { "start" : 51, "end" : 1396, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-121, "familyName" : "", "score" : 409.1, "model-ac" : "PTHR46704" }, { "signature" : { "accession" : "SSF88723", "name" : "PIN domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029060", "name" : "PIN-like_dom_sf", "description" : "PIN-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1044, "end" : 1200, "hmmLength" : 219, "location-fragments" : [ { "start" : 1044, "end" : 1200, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.84E-5, "model-ac" : "0040885" } ], "xref" : [ { "name" : "XP_018910409.1 PREDICTED: uncharacterized protein LOC109039395 [Bemisia tabaci]", "id" : "XP_018910409.1" } ] },{ "sequence" : "MTTNNYFGFTHGTQYSATPGTTYPTQQTGYSVTPGATAAAYPTQRTATGYETYQTQATPTAYAAGATTATTYDYGYARTAHSSPTAYDAKAYYQQQANPATPVTPAYSTSDYQTAGAAIVKPQYSATYSTQTTPQRQVVPPKPAVSAVQYSQYAPPQQQQQTPAQAVSSYTASYSTPASIQPTSQLNKAIGSAPRAITQRAPQQAVQQQTTGYQYTQRHPFKPQQQQQQQPPPQQVSQVQQLSQLQQQQQQQQHQQVQQQHAQLQQQQQQQQQQQQQQQVQQQQIKKPYQASPVSNVGSYQVNNPSTAQAAFVAQSTAAATNSNYNKPKPGYDTALFNAASHYINQQSGPNQNKPFYKKSFGNNASGLKNLRPKAPPKSQQLHYCEVCKISCAGPLTYREHLEGQKHKKKEAALKSDAPAPTISRGPISLHCDLCAVTCTGQDAYGAHIRGNKHQKVLKLHAMLGKPVPDIPEDPKIVVAKSIAAAKANQNTTAPDGKKTVVVPPKVNFVQSGSLSTTTKPEPKAEGKENTKSESTPEPKTEDIEMAAATLLENEVTPVGHEFVEEIKDELGKLVSFNCKLCECKFNDPNAKEMHMKGRRHRLAFKKKVNPNLQVDVKPSFNKKKHFEEKTRRTGGGGGPREEFMRGNQRNMHWQDRMMEVEERMYWDERRRFEEEMEFMEWGRRFHGPGMMPPPFPPGPGPRMMGPPFMPPPPPPQFPRRLDTSDDRHVIARHAAVYPNEQELKALQKIVSHTEKALKLVSDFLTENAQSTTDKKNGTSEVKTEVKVEPKTAESPAKPNATPNKKGPQKTKEDGRDGSLFSFEKETEERVLKGVMRVESLAKGLLLHGDTHVKLVVLCSEKPTRALLVKVAANLPSQLSIVAPEDSYLTNMKSEEAAITVQTKTEPKLTVSVILTSPLLREQVNAAGSDAPAAQSTPDPPDLLNKKKCLDALAALRHAKWFQARVAGMQNCLMIIRIFRDLCQRVPTWAPFSPWAMELLCEKALSSAGMPLSPGDSLRRVLEAVSSGVILQNGPGILDPCEKEPVDAAANLTPQQREDITASAQHALRLLAFRQIHKVLGMEPLPAPPPMPTNKFNNRGGYNRFGRKRRRDNSSGENTDSDAGVNEKKDKKDTDVVIKVEGAKVSSPAAATTPAKPAEAAKAPAATPAAAKGSLKSPAAAKPAVKK", "md5" : "3f0eacd806eee948bc8c5d3914295697", "matches" : [ { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 374, "end" : 417, "hmmStart" : 15, "hmmEnd" : 50, "hmmLength" : 60, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-11, "score" : 45.2, "envelopeStart" : 374, "envelopeEnd" : 417, "postProcessed" : true, "location-fragments" : [ { "start" : 374, "end" : 417, "dc-status" : "CONTINUOUS" } ] }, { "start" : 427, "end" : 467, "hmmStart" : 18, "hmmEnd" : 56, "hmmLength" : 60, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-8, "score" : 35.7, "envelopeStart" : 427, "envelopeEnd" : 467, "postProcessed" : true, "location-fragments" : [ { "start" : 427, "end" : 467, "dc-status" : "CONTINUOUS" } ] }, { "start" : 568, "end" : 610, "hmmStart" : 18, "hmmEnd" : 48, "hmmLength" : 60, "hmmBounds" : "COMPLETE", "evalue" : 3.2E-6, "score" : 28.5, "envelopeStart" : 568, "envelopeEnd" : 610, "postProcessed" : true, "location-fragments" : [ { "start" : 568, "end" : 610, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-23, "score" : 83.8, "model-ac" : "2mknA00" }, { "signature" : { "accession" : "SM00451", "name" : "ZnF_U1_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003604", "name" : "Matrin/U1-like-C_Znf_C2H2", "description" : "Matrin/U1-C-like, C2H2-type zinc finger", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 380, "end" : 414, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 37, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-7, "score" : 39.6, "location-fragments" : [ { "start" : 380, "end" : 414, "dc-status" : "CONTINUOUS" } ] }, { "start" : 574, "end" : 608, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 37, "hmmBounds" : "COMPLETE", "evalue" : 0.0012, "score" : 28.1, "location-fragments" : [ { "start" : 574, "end" : 608, "dc-status" : "CONTINUOUS" } ] }, { "start" : 427, "end" : 461, "hmmStart" : 1, "hmmEnd" : 37, "hmmLength" : 37, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-4, "score" : 30.7, "location-fragments" : [ { "start" : 427, "end" : 461, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.5E-25, "score" : 98.4, "model-ac" : "SM00451" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 778, "end" : 792, "location-fragments" : [ { "start" : 778, "end" : 792, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 150, "end" : 168, "location-fragments" : [ { "start" : 150, "end" : 168, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1083, "end" : 1187, "location-fragments" : [ { "start" : 1083, "end" : 1187, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 183, "end" : 241, "location-fragments" : [ { "start" : 183, "end" : 241, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 512, "end" : 542, "location-fragments" : [ { "start" : 512, "end" : 542, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 522, "end" : 541, "location-fragments" : [ { "start" : 522, "end" : 541, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 370, "end" : 415, "hmmLength" : 72, "location-fragments" : [ { "start" : 370, "end" : 415, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.53E-10, "model-ac" : "0053677" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 557, "end" : 608, "hmmLength" : 72, "location-fragments" : [ { "start" : 557, "end" : 608, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.48E-8, "model-ac" : "0053677" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 247, "end" : 286, "location-fragments" : [ { "start" : 247, "end" : 286, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF07528", "name" : "DZF", "description" : "DZF domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006561", "name" : "DZF_dom", "description" : "DZF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 837, "end" : 1087, "hmmStart" : 1, "hmmEnd" : 247, "hmmLength" : 248, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.2E-66, "score" : 222.8, "envelopeStart" : 837, "envelopeEnd" : 1088, "postProcessed" : true, "location-fragments" : [ { "start" : 837, "end" : 1087, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-66, "score" : 223.6, "model-ac" : "PF07528" }, { "signature" : { "accession" : "PTHR45762", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 149, "end" : 1134, "hmmStart" : 1, "hmmEnd" : 793, "hmmLength" : 807, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 149, "envelopeEnd" : 1145, "location-fragments" : [ { "start" : 149, "end" : 1134, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-262, "familyName" : "ZINC-FINGER PROTEIN AT 72D, ISOFORM B", "score" : 874.7, "model-ac" : "PTHR45762" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 149, "end" : 168, "location-fragments" : [ { "start" : 149, "end" : 168, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR45762:SF5", "name" : "ZINC-FINGER PROTEIN AT 72D, ISOFORM B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 149, "end" : 1134, "hmmStart" : 1, "hmmEnd" : 793, "hmmLength" : 807, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 149, "envelopeEnd" : 1145, "location-fragments" : [ { "start" : 149, "end" : 1134, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-262, "familyName" : "ZINC-FINGER PROTEIN AT 72D, ISOFORM B", "score" : 874.7, "model-ac" : "PTHR45762:SF5" }, { "signature" : { "accession" : "SM00572", "name" : "rich3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006561", "name" : "DZF_dom", "description" : "DZF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 831, "end" : 1088, "hmmStart" : 1, "hmmEnd" : 263, "hmmLength" : 263, "hmmBounds" : "COMPLETE", "evalue" : 7.9E-126, "score" : 434.0, "location-fragments" : [ { "start" : 831, "end" : 1088, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-126, "score" : 434.0, "model-ac" : "SM00572" }, { "signature" : { "accession" : "SM00355", "name" : "c2h2final6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 383, "end" : 407, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 5.7, "score" : 15.5, "location-fragments" : [ { "start" : 383, "end" : 407, "dc-status" : "CONTINUOUS" } ] }, { "start" : 430, "end" : 454, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 7.0, "score" : 14.7, "location-fragments" : [ { "start" : 430, "end" : 454, "dc-status" : "CONTINUOUS" } ] }, { "start" : 577, "end" : 601, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.66, "score" : 19.0, "location-fragments" : [ { "start" : 577, "end" : 601, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-10, "score" : 49.2, "model-ac" : "SM00355" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 579, "end" : 601, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M5I1M", "alignment" : "CklCeckFndpnakemHmkgrrH", "location-fragments" : [ { "start" : 579, "end" : 601, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS51703", "name" : "DZF", "description" : "DZF domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR006561", "name" : "DZF_dom", "description" : "DZF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 707, "end" : 1115, "score" : 95.983, "alignment" : "PPFM-PPPPPPQFPRRLDTSDDRHVIARHAAVYPNEQELKALQKIVSHTEKALKLVSDFLTENAQSTTDKKngtsevktevkvepktaespakpnatpnkkgpqktkedgrdGSLFSFEKETEERVLKGVMRVESLAKGLLLHGDTHVKLVVLCSEKPTRALLVKVAANLPSQLSIvapEDSYLTNMKSEEAAITVQTKtepkltvsviltspllREQVNAAGSDAPAAQSTPDPPDLLNKKKCLDALAALRHAKWFQARVAGMQNCLMIIRIFRDLCQRVPTWAPFSPWAMELLCEKALSSAGMPLSPGDSLRRVLEAVSSGVILQNGPGILDPCEKEPVDAAANLTPQQREDITASAQHALRLLAFRQIHKVLGMEPLPAPPPMPTNKFNN------RGGYNRFGRKRRRDNSS", "location-fragments" : [ { "start" : 707, "end" : 1115, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51703" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1107, "end" : 1139, "location-fragments" : [ { "start" : 1107, "end" : 1139, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 772, "end" : 821, "location-fragments" : [ { "start" : 772, "end" : 821, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 430, "end" : 463, "hmmLength" : 72, "location-fragments" : [ { "start" : 430, "end" : 463, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.27E-6, "model-ac" : "0053677" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 807, "end" : 821, "location-fragments" : [ { "start" : 807, "end" : 821, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF12874", "name" : "zf-met", "description" : "Zinc-finger of C2H2 type", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 384, "end" : 407, "hmmStart" : 2, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.6E-6, "score" : 27.2, "envelopeStart" : 383, "envelopeEnd" : 407, "postProcessed" : true, "location-fragments" : [ { "start" : 384, "end" : 407, "dc-status" : "CONTINUOUS" } ] }, { "start" : 431, "end" : 454, "hmmStart" : 2, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.5E-4, "score" : 22.0, "envelopeStart" : 430, "envelopeEnd" : 454, "postProcessed" : true, "location-fragments" : [ { "start" : 431, "end" : 454, "dc-status" : "CONTINUOUS" } ] }, { "start" : 577, "end" : 601, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-5, "score" : 25.0, "envelopeStart" : 577, "envelopeEnd" : 601, "postProcessed" : true, "location-fragments" : [ { "start" : 577, "end" : 601, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-18, "score" : 65.9, "model-ac" : "PF12874" } ], "xref" : [ { "name" : "XP_018909582.1 PREDICTED: zinc finger RNA-binding protein-like isoform X3 [Bemisia tabaci]", "id" : "XP_018909582.1" } ] },{ "sequence" : "MEDMDHRESDLEGSMSSPEMSDGEDMGDEDIDDQMHREIEEHNDDDRKKLRMAEKMAKLTKSALFHERDRIIRRGGSGLSFSQAEDMGLLTPTATAASPMVPPPPFSLPLPFPFLHPAAALPFLPPSAPVNVHQTSSASSHSSESSSSSQQTWSFEEQFKQLYELSDDPKRKEFLDDLFSFMQRRGTPINRLPIMAKSVLDLYELYNLVIQRGGLVDVINKKLWQEIIKGLNLPSSITSAAFTLRTQYMKYLYPYECEKKRLSSPSELQAAIDGNRREGRRGSYGAMAYADMVHRSPTSMVDIPQSVSPAQPQPQPQPLNLVTTTSPRRPHSAHSATLNGNGNGHHNNHHSAHHPSRDSTATVNSHLSSHMLPPSSGDESSRPGSNNSSLVVSMDINGIMYQGVLFAQSATNSASQNSRPSMIAYMQHNHDYLFRCDSKDSQSLS", "md5" : "05be82c88abcc55393d7dba943a16e46", "matches" : [ { "signature" : { "accession" : "SSF46774", "name" : "ARID-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036431", "name" : "ARID_dom_sf", "description" : "ARID DNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 151, "end" : 274, "hmmLength" : 128, "location-fragments" : [ { "start" : 151, "end" : 274, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.19E-37, "model-ac" : "0046063" }, { "signature" : { "accession" : "G3DSA:1.10.150.60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036431", "name" : "ARID_dom_sf", "description" : "ARID DNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 145, "end" : 281, "hmmStart" : 5, "hmmEnd" : 137, "hmmLength" : 137, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-60, "score" : 203.5, "envelopeStart" : 145, "envelopeEnd" : 281, "postProcessed" : true, "location-fragments" : [ { "start" : 145, "end" : 281, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-60, "score" : 204.3, "model-ac" : "4ljxA00" }, { "signature" : { "accession" : "SM00501", "name" : "bright_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001606", "name" : "ARID_dom", "description" : "ARID DNA-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 169, "end" : 261, "hmmStart" : 1, "hmmEnd" : 95, "hmmLength" : 95, "hmmBounds" : "COMPLETE", "evalue" : 6.5E-37, "score" : 138.6, "location-fragments" : [ { "start" : 169, "end" : 261, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-37, "score" : 138.6, "model-ac" : "SM00501" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 317, "end" : 346, "location-fragments" : [ { "start" : 317, "end" : 346, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51486", "name" : "REKLES", "description" : "REKLES domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR023334", "name" : "REKLES_domain", "description" : "REKLES domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 321, "end" : 412, "score" : 11.035, "alignment" : "LVTTTSPRRPHSAHSATLNGNGNGHHNNHHSAHHPSRdSTATVNSHLSSHMLPPSSgdESSRPGS-------NNSSLVVSMDINGIMYQGVLFAQSATN", "location-fragments" : [ { "start" : 321, "end" : 412, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51486" }, { "signature" : { "accession" : "PTHR15348", "name" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 287, "hmmStart" : 76, "hmmEnd" : 354, "hmmLength" : 588, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 306, "location-fragments" : [ { "start" : 12, "end" : 287, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-96, "familyName" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A", "score" : 325.9, "model-ac" : "PTHR15348" }, { "signature" : { "accession" : "PTHR15348:SF1", "name" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 382, "end" : 419, "hmmStart" : 510, "hmmEnd" : 546, "hmmLength" : 588, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 325, "envelopeEnd" : 443, "location-fragments" : [ { "start" : 382, "end" : 419, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-96, "familyName" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A", "score" : 325.9, "model-ac" : "PTHR15348:SF1" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 52, "location-fragments" : [ { "start" : 1, "end" : 52, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 357, "end" : 389, "location-fragments" : [ { "start" : 357, "end" : 389, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 30, "end" : 52, "location-fragments" : [ { "start" : 30, "end" : 52, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM01014", "name" : "ARID_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 165, "end" : 256, "hmmStart" : 1, "hmmEnd" : 97, "hmmLength" : 97, "hmmBounds" : "COMPLETE", "evalue" : 8.3E-36, "score" : 135.0, "location-fragments" : [ { "start" : 165, "end" : 256, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-36, "score" : 135.0, "model-ac" : "SM01014" }, { "signature" : { "accession" : "PTHR15348:SF1", "name" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 287, "hmmStart" : 76, "hmmEnd" : 354, "hmmLength" : 588, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 306, "location-fragments" : [ { "start" : 12, "end" : 287, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-96, "familyName" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A", "score" : 325.9, "model-ac" : "PTHR15348:SF1" }, { "signature" : { "accession" : "PTHR15348", "name" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 382, "end" : 419, "hmmStart" : 510, "hmmEnd" : 546, "hmmLength" : 588, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 325, "envelopeEnd" : 443, "location-fragments" : [ { "start" : 382, "end" : 419, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-96, "familyName" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A", "score" : 325.9, "model-ac" : "PTHR15348" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 297, "end" : 389, "location-fragments" : [ { "start" : 297, "end" : 389, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF01388", "name" : "ARID", "description" : "ARID/BRIGHT DNA binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001606", "name" : "ARID_dom", "description" : "ARID DNA-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 171, "end" : 256, "hmmStart" : 2, "hmmEnd" : 90, "hmmLength" : 90, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.1E-21, "score" : 74.7, "envelopeStart" : 170, "envelopeEnd" : 256, "postProcessed" : true, "location-fragments" : [ { "start" : 171, "end" : 256, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-21, "score" : 75.7, "model-ac" : "PF01388" }, { "signature" : { "accession" : "cd16881", "name" : "ARID_Dri-like", "description" : "ARID_Dri-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 152, "end" : 276, "sites" : [ { "description" : "DNA binding site", "numLocations" : 21, "siteLocations" : [ { "start" : 192, "end" : 192, "residue" : "L" }, { "start" : 195, "end" : 195, "residue" : "M" }, { "start" : 237, "end" : 237, "residue" : "I" }, { "start" : 241, "end" : 241, "residue" : "A" }, { "start" : 194, "end" : 194, "residue" : "I" }, { "start" : 276, "end" : 276, "residue" : "R" }, { "start" : 242, "end" : 242, "residue" : "F" }, { "start" : 191, "end" : 191, "residue" : "R" }, { "start" : 196, "end" : 196, "residue" : "A" }, { "start" : 245, "end" : 245, "residue" : "R" }, { "start" : 243, "end" : 243, "residue" : "T" }, { "start" : 228, "end" : 228, "residue" : "I" }, { "start" : 238, "end" : 238, "residue" : "T" }, { "start" : 225, "end" : 225, "residue" : "Q" }, { "start" : 236, "end" : 236, "residue" : "S" }, { "start" : 197, "end" : 197, "residue" : "K" }, { "start" : 275, "end" : 275, "residue" : "N" }, { "start" : 239, "end" : 239, "residue" : "S" }, { "start" : 193, "end" : 193, "residue" : "P" }, { "start" : 222, "end" : 222, "residue" : "K" }, { "start" : 224, "end" : 224, "residue" : "W" } ] } ], "evalue" : 6.54201E-93, "score" : 274.466, "location-fragments" : [ { "start" : 152, "end" : 276, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd16881" }, { "signature" : { "accession" : "PS51011", "name" : "ARID", "description" : "ARID domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001606", "name" : "ARID_dom", "description" : "ARID DNA-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 168, "end" : 260, "score" : 31.145, "alignment" : "DPKRKEFLDDLFSFMQRRGTPINRLPIMAKSVLDLYELYNLVIQRGGLVDVINKKLWQEIIKGLNLPSSITSAAFTLRTQYMKYLYPYECEKK", "location-fragments" : [ { "start" : 168, "end" : 260, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51011" } ], "xref" : [ { "name" : "XP_018909716.1 PREDICTED: protein dead ringer homolog isoform X2 [Bemisia tabaci]", "id" : "XP_018909716.1" } ] },{ "sequence" : "METKKPFERLPTNVGPIHYELYLKPDLQSLTFSGNETIKIEIKSATNKIVLHAAELDVTNASVTLSSGETVTPDVSLSPDDELLTLSFIKELPPGQASLTCSFVGELNDKLKGFYRSKCIDPVSRKETYAAVTQFCAIDARKCFPCWDEPAVKAQFTVTLCVQDDKVALSNMPVIEESHDGEGNKILKFETTHVMSTYLVAIVVGDFDYVQDKTSNGVLVRVYTPVGRKNQGETALNFASKMLQYYEEYFKISYPLPKLDLIAIADFAYGAMENWGLITFRETRLLVDPANTSSWTRQAVAKCVGHELAHQWFGNLVTMEWWTHLWLNEGYASFTENLSVARLHPEFDIWTQFLHHHHNSALRLDALNNSHPIEVPIGHPSEIDEIFDRISYSKGASVIRMLHRYIGDDDFRKGMNLYLVRHAYKNASTEDLWAALEESSGKPLKEMMTTWTKQMGFPLLTIESSRQLDDSRELVISQAKFGGDGKATECNSLWLVPLSFCKSSSPQEACFATVLKERRATIIVPNVKPDEWLKLNCGTYGFYRTQYPGDLLLQFIPDIKRKTLAPLDRTGLLDDLFALVQCGNASTTTLMELMLGMEDEDNYVVWATINYCLSELAIILSDTALEEPFHKFGRRLMETIYKKVGWDPQPNESHLKTLLRSMVIDRLGQFGHDGVIAEAKKRFENHICKKEALTADLRAAVYKAVLSTNEKDIFETMLQLYKQEDLHEEKQRISNSLGVVKDAQLLMRVLEFAISDDVRAQSAVSMIVSVGLTAQGRELAWNFIKNNWQTFKNMYKDGILLISLVGQSTENFTSEEKAKDVENFFKQNPWPGVERTVRQSIESIRNHAAWLERDRDSIKDFLSKI", "md5" : "14679f7ae8e4e9a897adb7d203f96df8", "matches" : [ { "signature" : { "accession" : "SSF63737", "name" : "Leukotriene A4 hydrolase N-terminal domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR042097", "name" : "Aminopeptidase_N-like_N", "description" : "Aminopeptidase N-like , N-terminal", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4, "end" : 206, "hmmLength" : 208, "location-fragments" : [ { "start" : 4, "end" : 206, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.32E-54, "model-ac" : "0038696" }, { "signature" : { "accession" : "G3DSA:2.60.40.1730", "name" : "tricorn interacting facor f3 domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042097", "name" : "Aminopeptidase_N-like_N", "description" : "Aminopeptidase N-like , N-terminal", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 207, "hmmStart" : 13, "hmmEnd" : 219, "hmmLength" : 219, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-64, "score" : 220.1, "envelopeStart" : 1, "envelopeEnd" : 207, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 207, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.2E-65, "score" : 221.0, "model-ac" : "4kx7A01" }, { "signature" : { "accession" : "PTHR11533", "name" : "PROTEASE M1 ZINC METALLOPROTEASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 862, "hmmStart" : 25, "hmmEnd" : 889, "hmmLength" : 899, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 865, "location-fragments" : [ { "start" : 1, "end" : 862, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-302, "familyName" : "PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED", "score" : 1007.9, "model-ac" : "PTHR11533" }, { "signature" : { "accession" : "G3DSA:1.10.390.60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 209, "end" : 456, "hmmStart" : 4, "hmmEnd" : 275, "hmmLength" : 275, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-108, "score" : 363.3, "envelopeStart" : 209, "envelopeEnd" : 456, "postProcessed" : true, "location-fragments" : [ { "start" : 209, "end" : 456, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-108, "score" : 364.1, "model-ac" : "5ab0C02" }, { "signature" : { "accession" : "SSF55486", "name" : "Metalloproteases (\"zincins\"), catalytic domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 214, "end" : 463, "hmmLength" : 252, "location-fragments" : [ { "start" : 214, "end" : 463, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.61E-90, "model-ac" : "0038697" }, { "signature" : { "accession" : "cd09601", "name" : "M1_APN-Q_like", "description" : "M1_APN-Q_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR034016", "name" : "M1_APN-typ", "description" : "Aminopeptidase N-type", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 17, "end" : 453, "sites" : [ { "description" : "active site", "numLocations" : 13, "siteLocations" : [ { "start" : 273, "end" : 273, "residue" : "E" }, { "start" : 392, "end" : 392, "residue" : "Y" }, { "start" : 271, "end" : 271, "residue" : "A" }, { "start" : 333, "end" : 333, "residue" : "S" }, { "start" : 387, "end" : 387, "residue" : "F" }, { "start" : 329, "end" : 329, "residue" : "E" }, { "start" : 134, "end" : 134, "residue" : "Q" }, { "start" : 272, "end" : 272, "residue" : "M" }, { "start" : 306, "end" : 306, "residue" : "H" }, { "start" : 310, "end" : 310, "residue" : "H" }, { "start" : 136, "end" : 136, "residue" : "C" }, { "start" : 270, "end" : 270, "residue" : "G" }, { "start" : 307, "end" : 307, "residue" : "E" } ] }, { "description" : "Zn binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 329, "end" : 329, "residue" : "E" }, { "start" : 306, "end" : 306, "residue" : "H" }, { "start" : 310, "end" : 310, "residue" : "H" } ] } ], "evalue" : 0.0, "score" : 665.05, "location-fragments" : [ { "start" : 17, "end" : 453, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd09601" }, { "signature" : { "accession" : "PR00756", "name" : "ALADIPTASE", "description" : "Membrane alanyl dipeptidase (M1) family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001930", "name" : "Peptidase_M1", "description" : "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase", "type" : "FAMILY", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 267, "end" : 277, "pvalue" : 9.25E-7, "score" : 75.97, "motifNumber" : 3, "location-fragments" : [ { "start" : 267, "end" : 277, "dc-status" : "CONTINUOUS" } ] }, { "start" : 322, "end" : 334, "pvalue" : 6.01E-6, "score" : 61.95, "motifNumber" : 5, "location-fragments" : [ { "start" : 322, "end" : 334, "dc-status" : "CONTINUOUS" } ] }, { "start" : 189, "end" : 204, "pvalue" : 6.52E-8, "score" : 53.01, "motifNumber" : 2, "location-fragments" : [ { "start" : 189, "end" : 204, "dc-status" : "CONTINUOUS" } ] }, { "start" : 141, "end" : 156, "pvalue" : 8.3E-9, "score" : 59.71, "motifNumber" : 1, "location-fragments" : [ { "start" : 141, "end" : 156, "dc-status" : "CONTINUOUS" } ] }, { "start" : 303, "end" : 318, "pvalue" : 2.05E-8, "score" : 71.88, "motifNumber" : 4, "location-fragments" : [ { "start" : 303, "end" : 318, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.2E-29, "graphscan" : "IIIII", "model-ac" : "PR00756" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 676, "end" : 696, "location-fragments" : [ { "start" : 676, "end" : 696, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR11533:SF261", "name" : "PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 862, "hmmStart" : 25, "hmmEnd" : 889, "hmmLength" : 899, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 865, "location-fragments" : [ { "start" : 1, "end" : 862, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-302, "familyName" : "PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED", "score" : 1007.9, "model-ac" : "PTHR11533:SF261" }, { "signature" : { "accession" : "PF01433", "name" : "Peptidase_M1", "description" : "Peptidase family M1 domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR014782", "name" : "Peptidase_M1_dom", "description" : "Peptidase M1, membrane alanine aminopeptidase", "type" : "DOMAIN", "goXRefs" : [ { "name" : "metallopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008237" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 235, "end" : 451, "hmmStart" : 2, "hmmEnd" : 218, "hmmLength" : 218, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.3E-85, "score" : 284.7, "envelopeStart" : 234, "envelopeEnd" : 451, "postProcessed" : true, "location-fragments" : [ { "start" : 235, "end" : 451, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-85, "score" : 285.4, "model-ac" : "PF01433" }, { "signature" : { "accession" : "PF17900", "name" : "Peptidase_M1_N", "description" : "Peptidase M1 N-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 199, "hmmStart" : 2, "hmmEnd" : 186, "hmmLength" : 186, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.1E-49, "score" : 167.7, "envelopeStart" : 15, "envelopeEnd" : 199, "postProcessed" : true, "location-fragments" : [ { "start" : 16, "end" : 199, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-49, "score" : 168.5, "model-ac" : "PF17900" }, { "signature" : { "accession" : "PF11838", "name" : "ERAP1_C", "description" : "ERAP1-like C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR024571", "name" : "ERAP1-like_C_dom", "description" : "ERAP1-like C-terminal domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 532, "end" : 845, "hmmStart" : 1, "hmmEnd" : 314, "hmmLength" : 315, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.8E-76, "score" : 257.7, "envelopeStart" : 532, "envelopeEnd" : 846, "postProcessed" : true, "location-fragments" : [ { "start" : 532, "end" : 845, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-76, "score" : 258.5, "model-ac" : "PF11838" }, { "signature" : { "accession" : "G3DSA:2.60.40.1910", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 457, "end" : 547, "hmmStart" : 1, "hmmEnd" : 84, "hmmLength" : 84, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 6.7E-11, "score" : 44.2, "envelopeStart" : 456, "envelopeEnd" : 547, "postProcessed" : true, "location-fragments" : [ { "start" : 457, "end" : 547, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-11, "score" : 45.5, "model-ac" : "3rjoA01" }, { "signature" : { "accession" : "G3DSA:1.25.50.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 551, "end" : 865, "hmmStart" : 15, "hmmEnd" : 320, "hmmLength" : 332, "hmmBounds" : "COMPLETE", "evalue" : 4.7E-78, "score" : 264.3, "envelopeStart" : 551, "envelopeEnd" : 865, "postProcessed" : true, "location-fragments" : [ { "start" : 551, "end" : 865, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-78, "score" : 264.4, "model-ac" : "4kx7A04" } ], "xref" : [ { "name" : "XP_018910165.1 PREDICTED: puromycin-sensitive aminopeptidase-like [Bemisia tabaci]", "id" : "XP_018910165.1" }, { "name" : "XP_018910157.1 PREDICTED: puromycin-sensitive aminopeptidase-like [Bemisia tabaci]", "id" : "XP_018910157.1" }, { "name" : "XP_018910174.1 PREDICTED: puromycin-sensitive aminopeptidase-like [Bemisia tabaci]", "id" : "XP_018910174.1" } ] },{ "sequence" : "MSGASAVAGGLKKRNQERKKPDPKPQSQINKCLNEKRRREQENIYIEELAELIHALPDMSSLAVNKPDKCAILQETVNQIRHIKQQEASGSSDAVQQGEVSSSKPTLLANNIFGPLLLEALEGFYFIVNQDGKIECVSENVHQFIRFTRDELIGKSIYNFIHLGDHARFSSCLLPMSVGWSPLDRSSVDPLTTRKKIFNCRLLIGPSAGREETMEEKQQRIEKYETMQISSAQVPYPGEKSNGDTSTSSGGEVSSECADVGPCLLCVARRIPPNEKPMGTPTEQFTMKLDPSGKIVGVDTSCVSSTYSQYLNKDLTGRLVQELCHDQDFIKLDSHLKETLTTGCCMSAIYRLRLAAEKYVHVQTKSKYFKATGIDPDFIMATHSIISDNDVPATSDSSISGPSLSTSSVGGPLMPIVNGNLQGPPNSRRSTNESCNTITLNSNSAYHTFTLNNDISMSDLNDLFPTSTCSWDLNMPSNEERPSWDGPESRQSLTPAQSPLNPYSQATQPSPATNPPTTPFSNSFVFSPLPVLDEPKEQKEPLESASENGESARLRNLLTNKRSSTDSEDSQAAGRNKDRILKKLLDQEKEEGSENISVKIEEGMSGLVRRHSMGTPHTTPTHPPPDTPPAQQNKPSSGNNNMLLQLLNERKDDDDVEARAGLKKQNELLQHLFKEEDSSKHNSTDDNLNRGQSRKRPSEEGEDTGGQSAKKVSNPISNPVSILETLPPPPPPGSSASQQPNSKLWERNKMLASLLAEKPNTPTHIPPIPPSVISATPQDNIPRVNKVPAAWSGGSLQRQNAHGGLRNGPRPGTAPTRPQQPQQHNYMIENDQQPPRQWDNSNGPSWDSHQLSDPVLSDILDQVIDIVPDAIITDSSAIMNLLDVIESPNSLGYQFNTPNDKTAAIDAIQKSLMLCESTIKNSSYNNQLSAGQNSIQSAQAQQHQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQNYPPPPVYQQRPRFISQAPLGQRPPFTGANSHLAQQQLVIQQRSKLLQQQQQQQQKQRLLQQQQQQSLLIPSNAAATPQELQNIDSLMNNSVAPNVSLQRSSSVPDSQLSPSSYGNALLNSAPSQISPSQRAPPYSPLSHQQQTFSPVNGGVNSFPAVSSAAQQTGARLSPSGLSPFQQQLSPRVSQAGQVQVQVQAQTQVGQGNYPVMNSLSPGQQASGQWSPQSSNNSNRLTLQQQQNPMLNAQLTAGNTYNNTRAAFVQQRLVPQHQQQQQQLPSVRSLPSPSARASPFSSDSPSYQQNPNQQQQYRLQRTISAPPPLNTTPTHTTHLPGGGLRHYNPMKDSAMYPPPSHTHQHYMNYPLDPQSYYNPSTYGPPTPAENCRLPSSAAGGGNNGASEYVRQELRAVVGARQGGLRPSPQIQIAPGQVTSADLEALGLSYEMPSSGGNVSPKLWANMSSELAASSGQPGLPRPGMEDVGVRQGAEKSSLLQKLLSE", "md5" : "59fd199432be3833d7c5f108ab3554c1", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 817, "end" : 850, "location-fragments" : [ { "start" : 817, "end" : 850, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 549, "end" : 570, "location-fragments" : [ { "start" : 549, "end" : 570, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1431, "end" : 1470, "location-fragments" : [ { "start" : 1431, "end" : 1470, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00010", "name" : "HLH", "description" : "Helix-loop-helix DNA-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR011598", "name" : "bHLH_dom", "description" : "Myc-type, basic helix-loop-helix (bHLH) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 30, "end" : 83, "hmmStart" : 4, "hmmEnd" : 53, "hmmLength" : 54, "hmmBounds" : "INCOMPLETE", "evalue" : 3.9E-5, "score" : 23.6, "envelopeStart" : 27, "envelopeEnd" : 84, "postProcessed" : true, "location-fragments" : [ { "start" : 30, "end" : 83, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-5, "score" : 24.9, "model-ac" : "PF00010" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 474, "end" : 850, "location-fragments" : [ { "start" : 474, "end" : 850, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.450.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 122, "end" : 271, "hmmStart" : 1, "hmmEnd" : 111, "hmmLength" : 144, "hmmBounds" : "COMPLETE", "evalue" : 9.0E-18, "score" : 66.7, "envelopeStart" : 122, "envelopeEnd" : 271, "postProcessed" : true, "location-fragments" : [ { "start" : 122, "end" : 271, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-20, "score" : 74.8, "model-ac" : "4f3lA02" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1019, "end" : 1039, "location-fragments" : [ { "start" : 1019, "end" : 1039, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "G3DSA:4.10.280.10", "name" : "HLH", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036638", "name" : "HLH_DNA-bd_sf", "description" : "Helix-loop-helix DNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 34, "end" : 121, "hmmStart" : 2, "hmmEnd" : 77, "hmmLength" : 77, "hmmBounds" : "COMPLETE", "evalue" : 4.3E-22, "score" : 80.3, "envelopeStart" : 34, "envelopeEnd" : 121, "postProcessed" : true, "location-fragments" : [ { "start" : 34, "end" : 121, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-22, "score" : 80.3, "model-ac" : "4f3lA01" }, { "signature" : { "accession" : "SSF47459", "name" : "HLH, helix-loop-helix DNA-binding domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036638", "name" : "HLH_DNA-bd_sf", "description" : "Helix-loop-helix DNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 23, "end" : 91, "hmmLength" : 80, "location-fragments" : [ { "start" : 23, "end" : 91, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.69E-9, "model-ac" : "0035101" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1178, "end" : 1307, "location-fragments" : [ { "start" : 1178, "end" : 1307, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 938, "end" : 974, "location-fragments" : [ { "start" : 938, "end" : 974, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "G3DSA:3.30.450.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 279, "end" : 388, "hmmStart" : 5, "hmmEnd" : 112, "hmmLength" : 114, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-37, "score" : 130.5, "envelopeStart" : 279, "envelopeEnd" : 388, "postProcessed" : true, "location-fragments" : [ { "start" : 279, "end" : 388, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-38, "score" : 133.6, "model-ac" : "1oj5A00" }, { "signature" : { "accession" : "SM00353", "name" : "finulus", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR011598", "name" : "bHLH_dom", "description" : "Myc-type, basic helix-loop-helix (bHLH) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 89, "hmmStart" : 1, "hmmEnd" : 61, "hmmLength" : 61, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-9, "score" : 47.0, "location-fragments" : [ { "start" : 32, "end" : 89, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-9, "score" : 47.0, "model-ac" : "SM00353" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 707, "end" : 721, "location-fragments" : [ { "start" : 707, "end" : 721, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1178, "end" : 1303, "location-fragments" : [ { "start" : 1178, "end" : 1303, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR10684:SF4", "name" : "TAIMAN, ISOFORM G", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 442, "hmmStart" : 5, "hmmEnd" : 398, "hmmLength" : 1664, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 11, "envelopeEnd" : 466, "location-fragments" : [ { "start" : 15, "end" : 442, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-154, "familyName" : "TAIMAN, ISOFORM G", "score" : 518.0, "model-ac" : "PTHR10684:SF4" }, { "signature" : { "accession" : "cd00130", "name" : "PAS", "description" : "PAS", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 285, "end" : 364, "sites" : [ { "description" : "putative active site", "numLocations" : 9, "siteLocations" : [ { "start" : 326, "end" : 326, "residue" : "D" }, { "start" : 302, "end" : 302, "residue" : "C" }, { "start" : 324, "end" : 324, "residue" : "C" }, { "start" : 352, "end" : 352, "residue" : "L" }, { "start" : 298, "end" : 298, "residue" : "V" }, { "start" : 323, "end" : 323, "residue" : "L" }, { "start" : 357, "end" : 357, "residue" : "E" }, { "start" : 325, "end" : 325, "residue" : "H" }, { "start" : 310, "end" : 310, "residue" : "Y" } ] }, { "description" : "heme pocket", "numLocations" : 6, "siteLocations" : [ { "start" : 324, "end" : 324, "residue" : "C" }, { "start" : 335, "end" : 335, "residue" : "H" }, { "start" : 336, "end" : 336, "residue" : "L" }, { "start" : 364, "end" : 364, "residue" : "T" }, { "start" : 320, "end" : 320, "residue" : "V" }, { "start" : 332, "end" : 332, "residue" : "L" } ] } ], "evalue" : 9.70811E-4, "score" : 37.998, "location-fragments" : [ { "start" : 285, "end" : 364, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00130" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 396, "end" : 436, "location-fragments" : [ { "start" : 396, "end" : 436, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50112", "name" : "PAS", "description" : "PAS repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 117, "end" : 162, "score" : 12.357, "alignment" : "-------LLEALEGFYFIVNQDGKIECVSENVHQFIRFTRDELIGKS-IYNFIH------------------", "location-fragments" : [ { "start" : 117, "end" : 162, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50112" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1070, "end" : 1158, "location-fragments" : [ { "start" : 1070, "end" : 1158, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 632, "end" : 646, "location-fragments" : [ { "start" : 632, "end" : 646, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 34, "location-fragments" : [ { "start" : 1, "end" : 34, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 420, "end" : 436, "location-fragments" : [ { "start" : 420, "end" : 436, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 722, "end" : 736, "location-fragments" : [ { "start" : 722, "end" : 736, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00091", "name" : "pas_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 112, "end" : 178, "hmmStart" : 1, "hmmEnd" : 68, "hmmLength" : 68, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-6, "score" : 38.0, "location-fragments" : [ { "start" : 112, "end" : 178, "dc-status" : "CONTINUOUS" } ] }, { "start" : 272, "end" : 341, "hmmStart" : 1, "hmmEnd" : 68, "hmmLength" : 68, "hmmBounds" : "COMPLETE", "evalue" : 74.0, "score" : 4.8, "location-fragments" : [ { "start" : 272, "end" : 341, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-8, "score" : 42.8, "model-ac" : "SM00091" }, { "signature" : { "accession" : "SSF55785", "name" : "PYP-like sensor domain (PAS domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035965", "name" : "PAS-like_dom_sf", "description" : "PAS domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 121, "end" : 172, "hmmLength" : 109, "location-fragments" : [ { "start" : 121, "end" : 172, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.03E-11, "model-ac" : "0048579" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 967, "end" : 1005, "location-fragments" : [ { "start" : 967, "end" : 1005, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 232, "end" : 251, "location-fragments" : [ { "start" : 232, "end" : 251, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00083", "name" : "HLH", "description" : "HLH", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR011598", "name" : "bHLH_dom", "description" : "Myc-type, basic helix-loop-helix (bHLH) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 24, "end" : 88, "sites" : [ { "description" : "E-box/N-box specificity site", "numLocations" : 1, "siteLocations" : [ { "start" : 35, "end" : 35, "residue" : "E" } ] }, { "description" : "dimerization interface", "numLocations" : 14, "siteLocations" : [ { "start" : 70, "end" : 70, "residue" : "C" }, { "start" : 87, "end" : 87, "residue" : "E" }, { "start" : 41, "end" : 41, "residue" : "Q" }, { "start" : 42, "end" : 42, "residue" : "E" }, { "start" : 80, "end" : 80, "residue" : "I" }, { "start" : 73, "end" : 73, "residue" : "L" }, { "start" : 48, "end" : 48, "residue" : "E" }, { "start" : 86, "end" : 86, "residue" : "Q" }, { "start" : 45, "end" : 45, "residue" : "Y" }, { "start" : 79, "end" : 79, "residue" : "Q" }, { "start" : 77, "end" : 77, "residue" : "V" }, { "start" : 84, "end" : 84, "residue" : "K" }, { "start" : 49, "end" : 49, "residue" : "L" }, { "start" : 46, "end" : 46, "residue" : "I" } ] }, { "description" : "DNA binding region", "numLocations" : 8, "siteLocations" : [ { "start" : 27, "end" : 27, "residue" : "S" }, { "start" : 66, "end" : 66, "residue" : "K" }, { "start" : 34, "end" : 34, "residue" : "N" }, { "start" : 38, "end" : 38, "residue" : "R" }, { "start" : 69, "end" : 69, "residue" : "K" }, { "start" : 28, "end" : 28, "residue" : "Q" }, { "start" : 35, "end" : 35, "residue" : "E" }, { "start" : 36, "end" : 36, "residue" : "K" } ] } ], "evalue" : 3.31761E-8, "score" : 49.5199, "location-fragments" : [ { "start" : 24, "end" : 88, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00083" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 396, "end" : 413, "location-fragments" : [ { "start" : 396, "end" : 413, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 647, "end" : 706, "location-fragments" : [ { "start" : 647, "end" : 706, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 571, "end" : 597, "location-fragments" : [ { "start" : 571, "end" : 597, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF55785", "name" : "PYP-like sensor domain (PAS domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035965", "name" : "PAS-like_dom_sf", "description" : "PAS domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 283, "end" : 388, "hmmLength" : 109, "location-fragments" : [ { "start" : 283, "end" : 388, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.27E-9, "model-ac" : "0048579" }, { "signature" : { "accession" : "PS50888", "name" : "BHLH", "description" : "Myc-type, basic helix-loop-helix (bHLH) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR011598", "name" : "bHLH_dom", "description" : "Myc-type, basic helix-loop-helix (bHLH) domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein dimerization activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 26, "end" : 83, "score" : 12.9, "alignment" : "QSQINKCLNEKRRREQENIYIEELAELIHALPDMsslavNKPDKCAILQETVNQIRHI", "location-fragments" : [ { "start" : 26, "end" : 83, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50888" }, { "signature" : { "accession" : "cd00130", "name" : "PAS", "description" : "PAS", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 123, "end" : 173, "sites" : [ ], "evalue" : 1.54342E-7, "score" : 48.7835, "location-fragments" : [ { "start" : 123, "end" : 173, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00130" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 487, "end" : 525, "location-fragments" : [ { "start" : 487, "end" : 525, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF14598", "name" : "PAS_11", "description" : "PAS domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 282, "end" : 390, "hmmStart" : 1, "hmmEnd" : 112, "hmmLength" : 113, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.8E-31, "score" : 107.9, "envelopeStart" : 282, "envelopeEnd" : 391, "postProcessed" : true, "location-fragments" : [ { "start" : 282, "end" : 390, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-31, "score" : 107.9, "model-ac" : "PF14598" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 34, "location-fragments" : [ { "start" : 12, "end" : 34, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR10684", "name" : "NUCLEAR RECEPTOR COACTIVATOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR017426", "name" : "Nuclear_rcpt_coactivator", "description" : "Nuclear receptor coactivator", "type" : "FAMILY", "goXRefs" : [ { "name" : "nuclear receptor transcription coactivator activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030374" }, { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" }, { "name" : "regulation of transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006355" } ], "pathwayXRefs" : [ { "name" : "PPARA activates gene expression", "databaseName" : "Reactome", "id" : "R-HSA-1989781" }, { "name" : "Estrogen-dependent gene expression", "databaseName" : "Reactome", "id" : "R-HSA-9018519" }, { "name" : "Transcriptional regulation of white adipocyte differentiation", "databaseName" : "Reactome", "id" : "R-HSA-381340" } ] } }, "locations" : [ { "start" : 15, "end" : 442, "hmmStart" : 5, "hmmEnd" : 398, "hmmLength" : 1664, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 11, "envelopeEnd" : 466, "location-fragments" : [ { "start" : 15, "end" : 442, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-154, "familyName" : "TAIMAN, ISOFORM G", "score" : 518.0, "model-ac" : "PTHR10684" } ], "xref" : [ { "name" : "XP_018909646.1 PREDICTED: nuclear receptor coactivator 2-like isoform X4 [Bemisia tabaci]", "id" : "XP_018909646.1" } ] },{ "sequence" : "MSYGRPPPRIEGMVSLKVDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYSRESRGFAFVRFYDKRDAEDALDAMDGRLLDGRELRVQMARYGRPSSPYRHRRGRRRRSNSRSRSRSRSRGRRYSRSHSGSRSRSSDSKSSRGKSRSKSPKHSRSRSRSHS", "md5" : "1dd866ebf2db0432bdf5acc388194e5a", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 89, "end" : 161, "location-fragments" : [ { "start" : 89, "end" : 161, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR23147:SF145", "name" : "SERINE/ARGININE-RICH SPLICING FACTOR 2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR034893", "name" : "SRSF2-like", "description" : "Serine/arginine-rich splicing factor 2-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "regulation of alternative mRNA splicing, via spliceosome", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0000381" }, { "name" : "RNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003723" } ], "pathwayXRefs" : [ { "name" : "mRNA Splicing - Minor Pathway", "databaseName" : "Reactome", "id" : "R-HSA-72165" }, { "name" : "mRNA Splicing - Major Pathway", "databaseName" : "Reactome", "id" : "R-HSA-72163" }, { "name" : "Transport of Mature mRNA derived from an Intron-Containing Transcript", "databaseName" : "Reactome", "id" : "R-HSA-159236" }, { "name" : "RNA Polymerase II Transcription Termination", "databaseName" : "Reactome", "id" : "R-HSA-73856" }, { "name" : "mRNA 3'-end processing", "databaseName" : "Reactome", "id" : "R-HSA-72187" } ] } }, "locations" : [ { "start" : 1, "end" : 161, "hmmStart" : 1, "hmmEnd" : 185, "hmmLength" : 221, "hmmBounds" : "COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 161, "location-fragments" : [ { "start" : 1, "end" : 161, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-51, "familyName" : "SERINE/ARGININE-RICH SPLICING FACTOR 2", "score" : 177.5, "model-ac" : "PTHR23147:SF145" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 145, "end" : 161, "location-fragments" : [ { "start" : 145, "end" : 161, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00360", "name" : "rrm1_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 15, "end" : 88, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-26, "score" : 102.4, "location-fragments" : [ { "start" : 15, "end" : 88, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-26, "score" : 102.4, "model-ac" : "SM00360" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4, "end" : 98, "hmmStart" : 74, "hmmEnd" : 152, "hmmLength" : 165, "hmmBounds" : "COMPLETE", "evalue" : 3.1E-27, "score" : 97.5, "envelopeStart" : 4, "envelopeEnd" : 98, "postProcessed" : true, "location-fragments" : [ { "start" : 4, "end" : 98, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-27, "score" : 97.5, "model-ac" : "1hl6C00" }, { "signature" : { "accession" : "SSF54928", "name" : "RNA-binding domain, RBD", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035979", "name" : "RBD_domain_sf", "description" : "RNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 122, "hmmLength" : 146, "location-fragments" : [ { "start" : 6, "end" : 122, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-33, "model-ac" : "0047108" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 130, "end" : 144, "location-fragments" : [ { "start" : 130, "end" : 144, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 92, "score" : 19.4, "alignment" : "VSLKVDNLTYRTTPEDLRRVFERCGEVGDIYIPRDrYSRESRGFAFVRFYDKRDAEDALDAMDGRLLDGRELRVQMARY", "location-fragments" : [ { "start" : 14, "end" : 92, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" }, { "signature" : { "accession" : "PF00076", "name" : "RRM_1", "description" : "RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 17, "end" : 86, "hmmStart" : 2, "hmmEnd" : 70, "hmmLength" : 70, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 8.1E-21, "score" : 73.6, "envelopeStart" : 16, "envelopeEnd" : 86, "postProcessed" : true, "location-fragments" : [ { "start" : 17, "end" : 86, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-21, "score" : 74.1, "model-ac" : "PF00076" }, { "signature" : { "accession" : "PTHR23147", "name" : "SERINE/ARGININE RICH SPLICING FACTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 161, "hmmStart" : 1, "hmmEnd" : 185, "hmmLength" : 221, "hmmBounds" : "COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 161, "location-fragments" : [ { "start" : 1, "end" : 161, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-51, "familyName" : "SERINE/ARGININE-RICH SPLICING FACTOR 2", "score" : 177.5, "model-ac" : "PTHR23147" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 96, "end" : 129, "location-fragments" : [ { "start" : 96, "end" : 129, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd12311", "name" : "RRM_SRSF2_SRSF8", "description" : "RRM_SRSF2_SRSF8", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 88, "sites" : [ ], "evalue" : 3.57371E-42, "score" : 133.19, "location-fragments" : [ { "start" : 16, "end" : 88, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12311" } ], "xref" : [ { "name" : "XP_018910516.1 PREDICTED: serine/arginine-rich splicing factor 2 isoform X1 [Bemisia tabaci]", "id" : "XP_018910516.1" } ] },{ "sequence" : "MSPSPAKRPRRSSRLDECQSPKESPSFRSSPRFSVDSSSKIKKYADSSPDSDESDGENTSQEMRERKRSVRQSPRNSPCTPKAKRKLDVSDLHKKVLTPKQTSNQRLSFKDVTIYLNKIDEDSETIVEDSETEDSSPKPLSTSKSSSRIKRRLDSTNEFKAQDSPKEAETALRCSSRTKRRLESQDENLTLDKQEPLTPKSKQRIPKAEEAPKTPRSIHKHPEGKSGYSTPQSAKFKINPSTPRTPIDEARANLHISAVPKSLPCRKSEFDTVYNFLARKIESQSGGVMYISGVPGTGKTATVHKVIESLREEAEKEEIDPFIFIEVNALRVSEPRQAYVKIWKDLTGETVSVPVAQTSLEKKFSRSAKKATIILVDELDYLCNRRQDVIYNILDWTTKRDARLIVLTIANTMDLPERTLKGRVTSRMGLTRLMFQPYTHTQLQEIVMNRLDKFKVFQPDAVQLVSRKVAAVSGDARRALDICRRATEYADEKTLVTIIHVQKVLQSIFTGPRVMTIQNCSEMEKLVLRSLRDESLRTGVEETHLKKMYRGLTGLCGVEALHVPSIGSVSQLCTKLSNMGLIIAENSSNTYLYRKLLLNVSVDDLHFALNENFQ", "md5" : "00f94142c5c21033da9b76af4c77d237", "matches" : [ { "signature" : { "accession" : "PF09079", "name" : "Cdc6_C", "description" : "CDC6, C terminal winged helix domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR015163", "name" : "Cdc6_C", "description" : "Cdc6, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Assembly of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68867" }, { "name" : "Orc1 removal from chromatin", "databaseName" : "Reactome", "id" : "R-HSA-68949" }, { "name" : "CDC6 association with the ORC:origin complex", "databaseName" : "Reactome", "id" : "R-HSA-68689" }, { "name" : "Activation of ATR in response to replication stress", "databaseName" : "Reactome", "id" : "R-HSA-176187" }, { "name" : "Activation of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68962" }, { "name" : "CDT1 association with the CDC6:ORC:origin complex", "databaseName" : "Reactome", "id" : "R-HSA-68827" }, { "name" : "G1/S-Specific Transcription", "databaseName" : "Reactome", "id" : "R-HSA-69205" } ] } }, "locations" : [ { "start" : 536, "end" : 608, "hmmStart" : 8, "hmmEnd" : 84, "hmmLength" : 84, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.5E-7, "score" : 29.5, "envelopeStart" : 528, "envelopeEnd" : 608, "postProcessed" : true, "location-fragments" : [ { "start" : 536, "end" : 608, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-7, "score" : 31.2, "model-ac" : "PF09079" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 96, "end" : 111, "location-fragments" : [ { "start" : 96, "end" : 111, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 238, "location-fragments" : [ { "start" : 1, "end" : 238, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 244, "end" : 436, "hmmStart" : 11, "hmmEnd" : 194, "hmmLength" : 197, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-62, "score" : 212.2, "envelopeStart" : 244, "envelopeEnd" : 436, "postProcessed" : true, "location-fragments" : [ { "start" : 244, "end" : 436, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.0E-63, "score" : 213.3, "model-ac" : "3te6A01" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 252, "end" : 493, "hmmLength" : 287, "location-fragments" : [ { "start" : 252, "end" : 493, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.16E-33, "model-ac" : "0050374" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 147, "end" : 190, "location-fragments" : [ { "start" : 147, "end" : 190, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF17872", "name" : "AAA_lid_10", "description" : "AAA lid domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR041083", "name" : "AAA_lid_10", "description" : "AAA lid domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Activation of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68962" }, { "name" : "Orc1 removal from chromatin", "databaseName" : "Reactome", "id" : "R-HSA-68949" }, { "name" : "Activation of ATR in response to replication stress", "databaseName" : "Reactome", "id" : "R-HSA-176187" }, { "name" : "CDC6 association with the ORC:origin complex", "databaseName" : "Reactome", "id" : "R-HSA-68689" }, { "name" : "Assembly of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68867" }, { "name" : "G1/S-Specific Transcription", "databaseName" : "Reactome", "id" : "R-HSA-69205" }, { "name" : "CDT1 association with the CDC6:ORC:origin complex", "databaseName" : "Reactome", "id" : "R-HSA-68827" } ] } }, "locations" : [ { "start" : 457, "end" : 493, "hmmStart" : 45, "hmmEnd" : 81, "hmmLength" : 99, "hmmBounds" : "INCOMPLETE", "evalue" : 6.5E-10, "score" : 39.0, "envelopeStart" : 432, "envelopeEnd" : 500, "postProcessed" : true, "location-fragments" : [ { "start" : 457, "end" : 493, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-10, "score" : 41.2, "model-ac" : "PF17872" }, { "signature" : { "accession" : "PTHR10763", "name" : "CELL DIVISION CONTROL PROTEIN 6-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 36, "end" : 612, "hmmStart" : 91, "hmmEnd" : 712, "hmmLength" : 718, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 614, "location-fragments" : [ { "start" : 36, "end" : 612, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-160, "familyName" : "ORIGIN RECOGNITION COMPLEX SUBUNIT 1", "score" : 539.1, "model-ac" : "PTHR10763" }, { "signature" : { "accession" : "PTHR10763:SF23", "name" : "ORIGIN RECOGNITION COMPLEX SUBUNIT 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR020793", "name" : "ORC1", "description" : "Origin recognition complex, subunit 1", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "G1/S-Specific Transcription", "databaseName" : "Reactome", "id" : "R-HSA-69205" }, { "name" : "CDC6 association with the ORC:origin complex", "databaseName" : "Reactome", "id" : "R-HSA-68689" }, { "name" : "Orc1 removal from chromatin", "databaseName" : "Reactome", "id" : "R-HSA-68949" }, { "name" : "Activation of ATR in response to replication stress", "databaseName" : "Reactome", "id" : "R-HSA-176187" }, { "name" : "Assembly of the ORC complex at the origin of replication", "databaseName" : "Reactome", "id" : "R-HSA-68616" }, { "name" : "Activation of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68962" }, { "name" : "E2F-enabled inhibition of pre-replication complex formation", "databaseName" : "Reactome", "id" : "R-HSA-113507" }, { "name" : "CDT1 association with the CDC6:ORC:origin complex", "databaseName" : "Reactome", "id" : "R-HSA-68827" }, { "name" : "Assembly of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68867" } ] } }, "locations" : [ { "start" : 36, "end" : 612, "hmmStart" : 91, "hmmEnd" : 712, "hmmLength" : 718, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 614, "location-fragments" : [ { "start" : 36, "end" : 612, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-160, "familyName" : "ORIGIN RECOGNITION COMPLEX SUBUNIT 1", "score" : 539.1, "model-ac" : "PTHR10763:SF23" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 81, "end" : 95, "location-fragments" : [ { "start" : 81, "end" : 95, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00382", "name" : "AAA_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003593", "name" : "AAA+_ATPase", "description" : "AAA+ ATPase domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 285, "end" : 435, "hmmStart" : 1, "hmmEnd" : 92, "hmmLength" : 92, "hmmBounds" : "COMPLETE", "evalue" : 3.2E-6, "score" : 36.7, "location-fragments" : [ { "start" : 285, "end" : 435, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-6, "score" : 36.7, "model-ac" : "SM00382" }, { "signature" : { "accession" : "PF00004", "name" : "AAA", "description" : "ATPase family associated with various cellular activities (AAA)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR003959", "name" : "ATPase_AAA_core", "description" : "ATPase, AAA-type, core", "type" : "DOMAIN", "goXRefs" : [ { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 289, "end" : 430, "hmmStart" : 1, "hmmEnd" : 130, "hmmLength" : 132, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.7E-17, "score" : 62.6, "envelopeStart" : 289, "envelopeEnd" : 432, "postProcessed" : true, "location-fragments" : [ { "start" : 289, "end" : 430, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-17, "score" : 64.0, "model-ac" : "PF00004" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 197, "end" : 223, "location-fragments" : [ { "start" : 197, "end" : 223, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 42, "location-fragments" : [ { "start" : 19, "end" : 42, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 57, "end" : 72, "location-fragments" : [ { "start" : 57, "end" : 72, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00009", "name" : "AAA", "description" : "AAA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 269, "end" : 430, "sites" : [ { "description" : "arginine finger", "numLocations" : 1, "siteLocations" : [ { "start" : 423, "end" : 423, "residue" : "R" } ] }, { "description" : "Walker B motif", "numLocations" : 6, "siteLocations" : [ { "start" : 375, "end" : 375, "residue" : "L" }, { "start" : 373, "end" : 373, "residue" : "I" }, { "start" : 377, "end" : 377, "residue" : "D" }, { "start" : 378, "end" : 378, "residue" : "E" }, { "start" : 376, "end" : 376, "residue" : "V" }, { "start" : 374, "end" : 374, "residue" : "I" } ] }, { "description" : "Walker A motif", "numLocations" : 8, "siteLocations" : [ { "start" : 294, "end" : 294, "residue" : "V" }, { "start" : 297, "end" : 297, "residue" : "T" }, { "start" : 298, "end" : 298, "residue" : "G" }, { "start" : 300, "end" : 300, "residue" : "T" }, { "start" : 296, "end" : 296, "residue" : "G" }, { "start" : 293, "end" : 293, "residue" : "G" }, { "start" : 299, "end" : 299, "residue" : "K" }, { "start" : 295, "end" : 295, "residue" : "P" } ] }, { "description" : "ATP binding site", "numLocations" : 10, "siteLocations" : [ { "start" : 294, "end" : 294, "residue" : "V" }, { "start" : 297, "end" : 297, "residue" : "T" }, { "start" : 298, "end" : 298, "residue" : "G" }, { "start" : 377, "end" : 377, "residue" : "D" }, { "start" : 300, "end" : 300, "residue" : "T" }, { "start" : 296, "end" : 296, "residue" : "G" }, { "start" : 299, "end" : 299, "residue" : "K" }, { "start" : 295, "end" : 295, "residue" : "P" }, { "start" : 301, "end" : 301, "residue" : "A" }, { "start" : 409, "end" : 409, "residue" : "I" } ] } ], "evalue" : 5.80648E-8, "score" : 50.2223, "location-fragments" : [ { "start" : 269, "end" : 430, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00009" } ], "xref" : [ { "name" : "XP_018909919.1 PREDICTED: origin recognition complex subunit 1 [Bemisia tabaci]", "id" : "XP_018909919.1" } ] },{ "sequence" : "MVCLLSQQAAICLLVDGSISFQQWSRNSDLHINVVVMNWRNLPFILLLSCLFASCIAVDDHEHISKHLKVDGNEDEDEGEASSQVKIRYEIQSEPPEDLDDELDDAEAEQEDLLNSIVRIRALLLRQNVKSLDEMFKADTLRKLMRLFDIHPDEGTSPARLSNSRFPDSNGESSTNAEEEEENVSAFDRWINRAQNAINVAISAVKEHKELQESSQSGSVDFDDGVDIDSDILVFRDYKPDLENASEEEKKGYDLFNEAHVLLKNRKPPMQDVFKILEDAANLGNINAKLQIGWSKLFGAHMKQNVTEARKIFEEVAAQNVPFAQMTLGFLYASGIGIQADQAKALVHYTFAALGGNTWARMALGYRYWSGATVHSSCERALDFYRLVSNKVASDVSLSGGPTIQRVRLIEEAENVGYNTGMIENDLVEYYQLLAEKGDVKAQVVLGQLHYQGGRGVPLDLQKAVHFFSMAAESGNAIALAFLGKIYMEGNGDNIKQDNLTAFMYFKQAAEMNNPVGQAGLGLMYLQGQGVEKDYSKALHFFTQAAEQGWVDGQLQLGVMYFNGLGTPRDYELANKYFTQASQSGHVLAFYNLAQMHATGTGMLRSCSTASELFKNVAERGRWAKKLMISHTKYREGHINEAFVGYAFLSELGYEVAQSNAAFLLDRREVSLWQEERETYARALMYWSRAAAQGYSTAQVKLGDYYYYGLGTGVDYETAALHYKLASDSQHNAQAMFNLGYMHEQGLGMNKDLHLAKRCYDMAAETSPDAKIPATLALMKLSLFFSWKYLQEINWLSWLTLGVFQINWYEWLSLGLNDSFSDSSLFFMMAATAMLMYYLRRFPPDQR", "md5" : "502c4e3b1ecf312a09953c9af5c13199", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 103, "end" : 123, "location-fragments" : [ { "start" : 103, "end" : 123, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR11102", "name" : "SEL-1-LIKE PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 264, "end" : 795, "hmmStart" : 197, "hmmEnd" : 726, "hmmLength" : 794, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 164, "envelopeEnd" : 811, "location-fragments" : [ { "start" : 264, "end" : 795, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-230, "familyName" : "PROTEIN SEL-1 HOMOLOG 1", "score" : 767.8, "model-ac" : "PTHR11102" }, { "signature" : { "accession" : "SSF81901", "name" : "HCP-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 633, "end" : 769, "hmmLength" : 133, "location-fragments" : [ { "start" : 633, "end" : 769, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.19E-25, "model-ac" : "0047832" }, { "signature" : { "accession" : "G3DSA:1.25.40.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011990", "name" : "TPR-like_helical_dom_sf", "description" : "Tetratricopeptide-like helical domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 425, "end" : 783, "hmmStart" : 76, "hmmEnd" : 415, "hmmLength" : 467, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-86, "score" : 291.8, "envelopeStart" : 425, "envelopeEnd" : 783, "postProcessed" : true, "location-fragments" : [ { "start" : 425, "end" : 783, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-126, "score" : 422.8, "model-ac" : "4bwrA00" }, { "signature" : { "accession" : "SSF81901", "name" : "HCP-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 428, "end" : 519, "hmmLength" : 265, "location-fragments" : [ { "start" : 428, "end" : 519, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.59E-17, "model-ac" : "0048648" }, { "signature" : { "accession" : "SSF81901", "name" : "HCP-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 271, "end" : 388, "hmmLength" : 265, "location-fragments" : [ { "start" : 271, "end" : 388, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.62E-22, "model-ac" : "0048648" }, { "signature" : { "accession" : "PTHR11102:SF70", "name" : "PROTEIN SEL-1 HOMOLOG 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 264, "end" : 795, "hmmStart" : 197, "hmmEnd" : 726, "hmmLength" : 794, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 164, "envelopeEnd" : 811, "location-fragments" : [ { "start" : 264, "end" : 795, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-230, "familyName" : "PROTEIN SEL-1 HOMOLOG 1", "score" : 767.8, "model-ac" : "PTHR11102:SF70" }, { "signature" : { "accession" : "PF08238", "name" : "Sel1", "description" : "Sel1 repeat", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006597", "name" : "Sel1-like", "description" : "Sel1-like repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 733, "end" : 765, "hmmStart" : 1, "hmmEnd" : 35, "hmmLength" : 38, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 8.8E-6, "score" : 26.2, "envelopeStart" : 733, "envelopeEnd" : 765, "postProcessed" : true, "location-fragments" : [ { "start" : 733, "end" : 765, "dc-status" : "CONTINUOUS" } ] }, { "start" : 516, "end" : 549, "hmmStart" : 2, "hmmEnd" : 37, "hmmLength" : 38, "hmmBounds" : "INCOMPLETE", "evalue" : 1.2E-8, "score" : 35.3, "envelopeStart" : 515, "envelopeEnd" : 550, "postProcessed" : true, "location-fragments" : [ { "start" : 516, "end" : 549, "dc-status" : "CONTINUOUS" } ] }, { "start" : 553, "end" : 586, "hmmStart" : 3, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.7E-7, "score" : 31.1, "envelopeStart" : 551, "envelopeEnd" : 586, "postProcessed" : true, "location-fragments" : [ { "start" : 553, "end" : 586, "dc-status" : "CONTINUOUS" } ] }, { "start" : 697, "end" : 729, "hmmStart" : 2, "hmmEnd" : 36, "hmmLength" : 38, "hmmBounds" : "INCOMPLETE", "evalue" : 0.0012, "score" : 19.5, "envelopeStart" : 696, "envelopeEnd" : 731, "postProcessed" : true, "location-fragments" : [ { "start" : 697, "end" : 729, "dc-status" : "CONTINUOUS" } ] }, { "start" : 441, "end" : 476, "hmmStart" : 2, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.0E-4, "score" : 22.0, "envelopeStart" : 440, "envelopeEnd" : 476, "postProcessed" : true, "location-fragments" : [ { "start" : 441, "end" : 476, "dc-status" : "CONTINUOUS" } ] }, { "start" : 323, "end" : 357, "hmmStart" : 2, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 0.72, "score" : 10.6, "envelopeStart" : 322, "envelopeEnd" : 357, "postProcessed" : true, "location-fragments" : [ { "start" : 323, "end" : 357, "dc-status" : "CONTINUOUS" } ] }, { "start" : 591, "end" : 610, "hmmStart" : 5, "hmmEnd" : 26, "hmmLength" : 38, "hmmBounds" : "INCOMPLETE", "evalue" : 220.0, "score" : 2.7, "envelopeStart" : 588, "envelopeEnd" : 621, "postProcessed" : true, "location-fragments" : [ { "start" : 591, "end" : 610, "dc-status" : "CONTINUOUS" } ] }, { "start" : 478, "end" : 514, "hmmStart" : 2, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.2E-4, "score" : 22.7, "envelopeStart" : 477, "envelopeEnd" : 514, "postProcessed" : true, "location-fragments" : [ { "start" : 478, "end" : 514, "dc-status" : "CONTINUOUS" } ] }, { "start" : 681, "end" : 695, "hmmStart" : 24, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 8.0, "score" : 7.3, "envelopeStart" : 663, "envelopeEnd" : 695, "postProcessed" : true, "location-fragments" : [ { "start" : 681, "end" : 695, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-47, "score" : 157.1, "model-ac" : "PF08238" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 156, "end" : 184, "location-fragments" : [ { "start" : 156, "end" : 184, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF81901", "name" : "HCP-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 499, "end" : 662, "hmmLength" : 265, "location-fragments" : [ { "start" : 499, "end" : 662, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.67E-35, "model-ac" : "0048648" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 157, "end" : 173, "location-fragments" : [ { "start" : 157, "end" : 173, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00671", "name" : "sel1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006597", "name" : "Sel1-like", "description" : "Sel1-like repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 440, "end" : 476, "hmmStart" : 1, "hmmEnd" : 43, "hmmLength" : 43, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-8, "score" : 44.3, "location-fragments" : [ { "start" : 440, "end" : 476, "dc-status" : "CONTINUOUS" } ] }, { "start" : 358, "end" : 393, "hmmStart" : 1, "hmmEnd" : 43, "hmmLength" : 43, "hmmBounds" : "COMPLETE", "evalue" : 64.0, "score" : 6.6, "location-fragments" : [ { "start" : 358, "end" : 393, "dc-status" : "CONTINUOUS" } ] }, { "start" : 587, "end" : 622, "hmmStart" : 1, "hmmEnd" : 43, "hmmLength" : 43, "hmmBounds" : "COMPLETE", "evalue" : 0.056, "score" : 22.6, "location-fragments" : [ { "start" : 587, "end" : 622, "dc-status" : "CONTINUOUS" } ] }, { "start" : 286, "end" : 321, "hmmStart" : 1, "hmmEnd" : 43, "hmmLength" : 43, "hmmBounds" : "COMPLETE", "evalue" : 71.0, "score" : 6.3, "location-fragments" : [ { "start" : 286, "end" : 321, "dc-status" : "CONTINUOUS" } ] }, { "start" : 696, "end" : 731, "hmmStart" : 1, "hmmEnd" : 43, "hmmLength" : 43, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-7, "score" : 40.8, "location-fragments" : [ { "start" : 696, "end" : 731, "dc-status" : "CONTINUOUS" } ] }, { "start" : 322, "end" : 357, "hmmStart" : 1, "hmmEnd" : 43, "hmmLength" : 43, "hmmBounds" : "COMPLETE", "evalue" : 7.8E-7, "score" : 38.7, "location-fragments" : [ { "start" : 322, "end" : 357, "dc-status" : "CONTINUOUS" } ] }, { "start" : 477, "end" : 514, "hmmStart" : 1, "hmmEnd" : 43, "hmmLength" : 43, "hmmBounds" : "COMPLETE", "evalue" : 3.5E-5, "score" : 33.2, "location-fragments" : [ { "start" : 477, "end" : 514, "dc-status" : "CONTINUOUS" } ] }, { "start" : 733, "end" : 768, "hmmStart" : 1, "hmmEnd" : 43, "hmmLength" : 43, "hmmBounds" : "COMPLETE", "evalue" : 8.1E-8, "score" : 42.0, "location-fragments" : [ { "start" : 733, "end" : 768, "dc-status" : "CONTINUOUS" } ] }, { "start" : 515, "end" : 550, "hmmStart" : 1, "hmmEnd" : 43, "hmmLength" : 43, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-11, "score" : 53.5, "location-fragments" : [ { "start" : 515, "end" : 550, "dc-status" : "CONTINUOUS" } ] }, { "start" : 551, "end" : 586, "hmmStart" : 1, "hmmEnd" : 43, "hmmLength" : 43, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-10, "score" : 50.1, "location-fragments" : [ { "start" : 551, "end" : 586, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-97, "score" : 338.0, "model-ac" : "SM00671" }, { "signature" : { "accession" : "G3DSA:1.25.40.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011990", "name" : "TPR-like_helical_dom_sf", "description" : "Tetratricopeptide-like helical domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 103, "end" : 398, "hmmStart" : 237, "hmmEnd" : 385, "hmmLength" : 434, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-26, "score" : 94.8, "envelopeStart" : 103, "envelopeEnd" : 398, "postProcessed" : true, "location-fragments" : [ { "start" : 103, "end" : 398, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.6E-118, "score" : 396.6, "model-ac" : "3e4bA00" } ], "xref" : [ { "name" : "XP_018909659.1 PREDICTED: protein sel-1 homolog 1-like [Bemisia tabaci]", "id" : "XP_018909659.1" } ] },{ "sequence" : "MKTAIMDIDPMYLSFSVPNGVPQESKLATYMKQRQPERVPQLTTVTSPVSKRINPINGVDQLSSSLRKMGVQSAEFVPRPNLSSTYSNSVSPTHRQASTPSPTSLVTQAPAFEKNLQTYQENVGGTTYFYPQTVPSEEPPSAVVDEVSTSSNASGVTVYPGTPSHLRNKNNPPPTDPAASYFVNNSLRLEIQYKNSLVLAQADPEQFPDLPSEVDNYHELVPLEPPRPLHKQSMLGYQATSYKATHIKTGIRYCLRRIHDYRLPSTKCTILVDMWKKLSHSNIVQLKEVFTTKAFGDHSILFVYDYHPDSETFQTRYFSQAEPMNGFNDLFSSNSHQPRPYSHMKNALLRQQQSMIPESTIWNYVIQLTGALRVIHSAGLAFRTLDATKVILNGRSRIRLSFCAITDVLSFDPNASNPLALIPHLQQEDLTQLGKLILALVHKSLFAVQAENLQTSLDLMARSYSADLRHLVTYLLSSQRRTVVDLMPMIGARFYSQLDATQIHCDYLENELAKEIENGRLFRLLVKLSTINERPELNMDPAWSETGDRYMVKLLRDYLFHQVTEDGRPWLDMAHIVHCLNKLDAGTQERICLMSRDEQSILVVSYAELKQCVEQSFSELVNAASVVPAKAE", "md5" : "16b0631691421b2d8dc0a7e98325da87", "matches" : [ { "signature" : { "accession" : "cd00180", "name" : "PKc", "description" : "PKc", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 236, "end" : 401, "sites" : [ { "description" : "polypeptide substrate binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 237, "end" : 237, "residue" : "Y" }, { "start" : 329, "end" : 329, "residue" : "D" }, { "start" : 388, "end" : 388, "residue" : "T" }, { "start" : 386, "end" : 386, "residue" : "D" }, { "start" : 331, "end" : 331, "residue" : "F" }, { "start" : 384, "end" : 384, "residue" : "T" } ] } ], "evalue" : 2.06903E-10, "score" : 58.8211, "location-fragments" : [ { "start" : 236, "end" : 401, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00180" }, { "signature" : { "accession" : "G3DSA:1.10.510.10", "name" : "Transferase(Phosphotransferase) domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 211, "end" : 490, "hmmStart" : 1, "hmmEnd" : 276, "hmmLength" : 276, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-106, "score" : 357.1, "envelopeStart" : 211, "envelopeEnd" : 490, "postProcessed" : true, "location-fragments" : [ { "start" : 211, "end" : 490, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-106, "score" : 357.5, "model-ac" : "4bwpB01" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 236, "end" : 479, "hmmLength" : 293, "location-fragments" : [ { "start" : 356, "end" : 479, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 236, "end" : 323, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.63E-13, "model-ac" : "0046210" }, { "signature" : { "accession" : "PF18101", "name" : "Pan3_PK", "description" : "Pan3 Pseudokinase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR041332", "name" : "Pan3_PK", "description" : "Pan3 pseudokinase domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Deadenylation of mRNA", "databaseName" : "Reactome", "id" : "R-HSA-429947" } ] } }, "locations" : [ { "start" : 484, "end" : 620, "hmmStart" : 2, "hmmEnd" : 138, "hmmLength" : 138, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.2E-64, "score" : 214.3, "envelopeStart" : 483, "envelopeEnd" : 620, "postProcessed" : true, "location-fragments" : [ { "start" : 484, "end" : 620, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-64, "score" : 215.1, "model-ac" : "PF18101" }, { "signature" : { "accession" : "MF_03181", "name" : "PAN3", "description" : "PAN2-PAN3 deadenylation complex subunit PAN3 [PAN3].", "signatureLibraryRelease" : { "library" : "HAMAP", "version" : "2020_01" }, "entry" : { "accession" : "IPR030844", "name" : "PAN3", "description" : "PAN2-PAN3 deadenylation complex subunit PAN3", "type" : "FAMILY", "goXRefs" : [ { "name" : "RNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003723" }, { "name" : "PAN complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0031251" }, { "name" : "nuclear-transcribed mRNA poly(A) tail shortening", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0000289" }, { "name" : "mRNA processing", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006397" } ], "pathwayXRefs" : [ { "name" : "Deadenylation of mRNA", "databaseName" : "Reactome", "id" : "R-HSA-429947" } ] } }, "locations" : [ { "start" : 22, "end" : 622, "score" : 29.195, "alignment" : "PQESKL---------------------------ATYMKQRQPERVP---------------------------------QLTTVTSPVSKRINPingvD-QLSSSlrkmGVqSA-EFVPR-----P-------------NlSSTYSNSvSPTHrqaS-TPSPT--SLVTQA--PafeknlqtyqenvGGTTYFYPQTvPSEEPPSA-----------------------VVDEVSTSSNASGVTVYPGTPSHLrnKNNPPPTDPAASYFVNNSLRLEIQyKNSLVLAQADPEQFPDLPSEVDNYHELVPLEPprplH-----KQSMLGYQATSYKATHIKTGIRYCLRRIHDYRLPSTK-CTILVDMWKKLSHSNIVQLKEVFTTKAFGDHSILFVYDYHPDSETFQTRYFSQaepmngfndlfSSN--------ShqprpyshmknallrqqqsMIPESTIWNYVIQLTGALRVIHSAGLAFRTLDATKVILNGRSRIRLSFCAITDVLSFDPnasnpLALIPHLQQEDLTQLGKLILALVHKSLFAVQAENLQTSLDLMARSYSADLRHLVTYLLSSQR-----RTVVDLMPMIGARFYSQLDATQIHCDYLENELAKEIENGRLFRLLVKLSTINERPELNMDPAWSETGDRYMVKLLRDYLFHQVTEDGRPWLDMAHIVHCLNKLDAGTQERICLMSRDEQSILVVSYAELKQCVEQSFSELVN", "location-fragments" : [ { "start" : 22, "end" : 622, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "MF_03181" }, { "signature" : { "accession" : "PTHR12272", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR030844", "name" : "PAN3", "description" : "PAN2-PAN3 deadenylation complex subunit PAN3", "type" : "FAMILY", "goXRefs" : [ { "name" : "RNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003723" }, { "name" : "PAN complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0031251" }, { "name" : "nuclear-transcribed mRNA poly(A) tail shortening", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0000289" }, { "name" : "mRNA processing", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006397" } ], "pathwayXRefs" : [ { "name" : "Deadenylation of mRNA", "databaseName" : "Reactome", "id" : "R-HSA-429947" } ] } }, "locations" : [ { "start" : 54, "end" : 625, "hmmStart" : 137, "hmmEnd" : 685, "hmmLength" : 690, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 13, "envelopeEnd" : 629, "location-fragments" : [ { "start" : 54, "end" : 625, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-210, "familyName" : "FAMILY NOT NAMED", "score" : 703.6, "model-ac" : "PTHR12272" }, { "signature" : { "accession" : "PS50011", "name" : "PROTEIN_KINASE_DOM", "description" : "Protein kinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 227, "end" : 495, "score" : 9.489, "alignment" : "RPLHKQSMLGYQATSYKATHIKTGIRYCLRRIHD----YRlPSTKCTILVDMWKKLSHSNIVQLKEVFTTKafgdHSILFVYDYHPDsetfqtryfsqaepmNGFNDLFSSNSHQprpyshmknallrqqqsmIPESTIWNYVIQLTGALRVIHSAGLAFRTLDATKVILNGRSRIRLSFCAITDVL-----SFDPNASNPLALIPHLQ--------QEDLTQLGKLILALVH-KSLFAVQaENLQTSLDLMARS-----------YSADLRHLVTYLLSSQRRTVVDLMPMIGARFY", "location-fragments" : [ { "start" : 227, "end" : 495, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50011" } ], "xref" : [ { "name" : "XP_018909963.1 PREDICTED: PAB-dependent poly(A)-specific ribonuclease subunit PAN3 [Bemisia tabaci]", "id" : "XP_018909963.1" }, { "name" : "XP_018909966.1 PREDICTED: PAB-dependent poly(A)-specific ribonuclease subunit PAN3 [Bemisia tabaci]", "id" : "XP_018909966.1" }, { "name" : "XP_018909964.1 PREDICTED: PAB-dependent poly(A)-specific ribonuclease subunit PAN3 [Bemisia tabaci]", "id" : "XP_018909964.1" }, { "name" : "XP_018909967.1 PREDICTED: PAB-dependent poly(A)-specific ribonuclease subunit PAN3 [Bemisia tabaci]", "id" : "XP_018909967.1" }, { "name" : "XP_018909965.1 PREDICTED: PAB-dependent poly(A)-specific ribonuclease subunit PAN3 [Bemisia tabaci]", "id" : "XP_018909965.1" }, { "name" : "XP_018909962.1 PREDICTED: PAB-dependent poly(A)-specific ribonuclease subunit PAN3 [Bemisia tabaci]", "id" : "XP_018909962.1" } ] },{ "sequence" : "MVILHVKKDDESQFLYETKVSESIDAVTTDIAFIYNGRLKISRICSEMEELAKHGTFYPPEILGLLEEQVAELKLTDEWGEKCSPSGGWKLNKDPIGRRNGRQPVEEMQQVLLNTVEEAKAMVSKKLVSGNKCLTLGTVQEAIRLLGGACSIVYPMGLPPHDPIREELENREQLEGTQASREVMEVAVARLWFSGRELNREKLLRDYVGPNDKSKLIVKLARLGQGAPAREPVVTEEVKRRMMADAFRRQEQLKQKDQSRQSFYCGLIVEQISKQ", "md5" : "c58c4ea50b08cada0befdf440c4bbd0c", "matches" : [ { "signature" : { "accession" : "PF11069", "name" : "CFAP298", "description" : "Cilia- and flagella-associated protein 298", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR021298", "name" : "CFAP298", "description" : "Cilia- and flagella-associated protein 298", "type" : "FAMILY", "goXRefs" : [ { "name" : "regulation of cilium movement", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0003352" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 189, "end" : 263, "hmmStart" : 1, "hmmEnd" : 75, "hmmLength" : 97, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.4E-24, "score" : 85.5, "envelopeStart" : 189, "envelopeEnd" : 271, "postProcessed" : true, "location-fragments" : [ { "start" : 189, "end" : 263, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-24, "score" : 86.7, "model-ac" : "PF11069" }, { "signature" : { "accession" : "PTHR13238", "name" : "PROTEIN C21ORF59", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR021298", "name" : "CFAP298", "description" : "Cilia- and flagella-associated protein 298", "type" : "FAMILY", "goXRefs" : [ { "name" : "regulation of cilium movement", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0003352" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 257, "hmmStart" : 181, "hmmEnd" : 437, "hmmLength" : 470, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 265, "location-fragments" : [ { "start" : 1, "end" : 257, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-104, "familyName" : "UPF0769 PROTEIN C21ORF59", "score" : 352.5, "model-ac" : "PTHR13238" }, { "signature" : { "accession" : "PTHR13238:SF4", "name" : "UPF0769 PROTEIN C21ORF59", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 257, "hmmStart" : 181, "hmmEnd" : 437, "hmmLength" : 470, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 265, "location-fragments" : [ { "start" : 1, "end" : 257, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-104, "familyName" : "UPF0769 PROTEIN C21ORF59", "score" : 352.5, "model-ac" : "PTHR13238:SF4" } ], "xref" : [ { "name" : "XP_018910322.1 PREDICTED: UPF0769 protein C21orf59 [Bemisia tabaci]", "id" : "XP_018910322.1" } ] },{ "sequence" : "MTAGVKAPWGALLALALACAATTGSEDDCAIAPPFHHIPGTYTVTGIFDIHHGANCSQVNENGFAMMTSAIHTIRLLNDIQYIPGVDVGLLIYDTCSKHEEAQKAVVQSHVMNECTLSVSLGILTTARIAEELKNLSQALQLNLSVVPEPVDTQVLIDSTVELLTVLGKKVVDVIISDDVDFSQGLVSAITKRKICVKKTTDMDTAEDLKITSSDGFLIIAGSAQYIQSKLKHFPRLTNCILVPLAGRLNMSEVAFIKNHHIMSIENSIFRVRSANNSRTHRDADHSELPETTEGTGNDSPETAGPETGSSETFLGHGNSNRQKFNEVLSKSEINKVDKLRILFELLHNGGMKNLDDIIHVEEEQEAETTGNADDSAEMDVTSSQEVTVSEASQDATSSQEVTSSGDDDRKSTAGEMTGGSSVEDSQESTVTHDEGVTSGAEETSTSDDGKATSEAQSTHSSAEPTEKADQKPHDEPEVVEQNLHNVDIQKSTEAHFRNPPEVIDRKHSEEDDGESVDSTIYRQVEKPRIYYINTIRMEPPPEVVQAERTAKRLPNSATHATEIRLEITARVITNGSSREVEIKEIEPVEDQIAEETVDSPEILPPSGISGVEDITESATEEVEVDMQTTPLIDLDGVTTESTLTTMDDKEYIEDSPIESSDPADKFRAFFSEDTELIKINLGLIRVARSVIKMIEQFKMDFNIRCFYETHNSSCGGKSERTAVTSTSSLDEEIASVARLLKFEKNVLINGLNVESAYGEILFEFNFDAEHSEWYMSKNGREVQPNATSYNICAITNCSECVNFQPEVVTSGRRIWEFLKRLSVKTDVYVVVLLTISVIGIILSLCVGTFIVVRILKKDILEGNPLLTMLLLLAVIFTYCAVLPFVLKVTDDGDLAYSTLPQNEEVFIYHKSSESVLYVQNILCLAKIIMMSTSFNLLFGIILARSLMLSNCDRDGSFLSHIDGYIQVTLLFFILLVQICVNVELYIFNARYDLKICIENSNMSLYFQIYNTFLLILCIITAPFIYKSRRNYNEGLYLTIVVIFLAIVWFVWISIYQFYDPSTTGIPNIKEMAALSGLVASATGVLILIFIPRTYLMLTGIVRDNITASLPTLGFTNSSSVLDVTQYRSTQALYDTVGQGNTIKSGQMNPNYYMERPTTPSTSKLEPTTSRTPENTYER", "md5" : "73f5b0bab51488c722495f5d2ceabc4b", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1145, "end" : 1179, "location-fragments" : [ { "start" : 1145, "end" : 1179, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 375, "end" : 403, "location-fragments" : [ { "start" : 375, "end" : 403, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR24060:SF138", "name" : "PROTEIN BRIDE OF SEVENLESS", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 822, "end" : 1107, "hmmStart" : 420, "hmmEnd" : 667, "hmmLength" : 758, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 819, "envelopeEnd" : 1164, "location-fragments" : [ { "start" : 822, "end" : 1107, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-35, "familyName" : "PROTEIN BRIDE OF SEVENLESS", "score" : 124.1, "model-ac" : "PTHR24060:SF138" }, { "signature" : { "accession" : "PR01223", "name" : "BRIDEOF7LESS", "description" : "Bride of sevenless protein signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002956", "name" : "Bride_of_7less", "description" : "Bride of sevenless protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "visual perception", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007601" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "sevenless binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005118" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 829, "end" : 854, "pvalue" : 1.76E-7, "score" : 42.31, "motifNumber" : 1, "location-fragments" : [ { "start" : 829, "end" : 854, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1035, "end" : 1059, "pvalue" : 8.04E-6, "score" : 26.67, "motifNumber" : 6, "location-fragments" : [ { "start" : 1035, "end" : 1059, "dc-status" : "CONTINUOUS" } ] }, { "start" : 868, "end" : 891, "pvalue" : 2.83E-6, "score" : 30.56, "motifNumber" : 2, "location-fragments" : [ { "start" : 868, "end" : 891, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-12, "graphscan" : "II...i.", "model-ac" : "PR01223" }, { "signature" : { "accession" : "SSF53822", "name" : "Periplasmic binding protein-like I", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR028082", "name" : "Peripla_BP_I", "description" : "Periplasmic binding protein-like I", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 205, "hmmLength" : 477, "location-fragments" : [ { "start" : 37, "end" : 205, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.59E-6, "model-ac" : "0046641" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 465, "end" : 482, "location-fragments" : [ { "start" : 465, "end" : 482, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 276, "end" : 324, "location-fragments" : [ { "start" : 276, "end" : 324, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 276, "end" : 292, "location-fragments" : [ { "start" : 276, "end" : 292, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR24060", "name" : "METABOTROPIC GLUTAMATE RECEPTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 822, "end" : 1107, "hmmStart" : 420, "hmmEnd" : 667, "hmmLength" : 758, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 819, "envelopeEnd" : 1164, "location-fragments" : [ { "start" : 822, "end" : 1107, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-35, "familyName" : "PROTEIN BRIDE OF SEVENLESS", "score" : 124.1, "model-ac" : "PTHR24060" }, { "signature" : { "accession" : "SSF81665", "name" : "Calcium ATPase, transmembrane domain M", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR023298", "name" : "ATPase_P-typ_TM_dom_sf", "description" : "P-type ATPase, transmembrane domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Ion transport by P-type ATPases", "databaseName" : "Reactome", "id" : "R-HSA-936837" } ] } }, "locations" : [ { "start" : 812, "end" : 1058, "hmmLength" : 474, "location-fragments" : [ { "start" : 812, "end" : 1058, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.44E-5, "model-ac" : "0049473" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 363, "end" : 500, "location-fragments" : [ { "start" : 363, "end" : 500, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00003", "name" : "7tm_3", "description" : "7 transmembrane sweet-taste receptor of 3 GCPR", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR017978", "name" : "GPCR_3_C", "description" : "GPCR family 3, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "G protein-coupled receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004930" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "G protein-coupled receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007186" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 846, "end" : 1095, "hmmStart" : 4, "hmmEnd" : 235, "hmmLength" : 236, "hmmBounds" : "INCOMPLETE", "evalue" : 7.3E-21, "score" : 75.1, "envelopeStart" : 829, "envelopeEnd" : 1096, "postProcessed" : true, "location-fragments" : [ { "start" : 846, "end" : 1095, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-21, "score" : 75.8, "model-ac" : "PF00003" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 293, "end" : 324, "location-fragments" : [ { "start" : 293, "end" : 324, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51257", "name" : "PROKAR_LIPOPROTEIN", "description" : "Prokaryotic membrane lipoprotein lipid attachment site profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 19, "score" : 5.0, "alignment" : "MTAG-VK---------------APWGALLALALAC", "location-fragments" : [ { "start" : 1, "end" : 19, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51257" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 415, "end" : 464, "location-fragments" : [ { "start" : 415, "end" : 464, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd15042", "name" : "7tmC_Boss", "description" : "7tmC_Boss", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 828, "end" : 1099, "sites" : [ { "description" : "putative dimer interface", "numLocations" : 13, "siteLocations" : [ { "start" : 876, "end" : 876, "residue" : "I" }, { "start" : 838, "end" : 838, "residue" : "V" }, { "start" : 839, "end" : 839, "residue" : "I" }, { "start" : 883, "end" : 883, "residue" : "L" }, { "start" : 884, "end" : 884, "residue" : "P" }, { "start" : 880, "end" : 880, "residue" : "C" }, { "start" : 835, "end" : 835, "residue" : "T" }, { "start" : 834, "end" : 834, "residue" : "L" }, { "start" : 842, "end" : 842, "residue" : "I" }, { "start" : 922, "end" : 922, "residue" : "I" }, { "start" : 831, "end" : 831, "residue" : "V" }, { "start" : 926, "end" : 926, "residue" : "A" }, { "start" : 841, "end" : 841, "residue" : "I" } ] }, { "description" : "putative allosteric modulator binding site", "numLocations" : 21, "siteLocations" : [ { "start" : 1049, "end" : 1049, "residue" : "W" }, { "start" : 1045, "end" : 1045, "residue" : "L" }, { "start" : 1081, "end" : 1081, "residue" : "S" }, { "start" : 931, "end" : 931, "residue" : "M" }, { "start" : 932, "end" : 932, "residue" : "S" }, { "start" : 1007, "end" : 1007, "residue" : "F" }, { "start" : 928, "end" : 928, "residue" : "I" }, { "start" : 1077, "end" : 1077, "residue" : "G" }, { "start" : 997, "end" : 997, "residue" : "C" }, { "start" : 927, "end" : 927, "residue" : "K" }, { "start" : 1008, "end" : 1008, "residue" : "Q" }, { "start" : 1052, "end" : 1052, "residue" : "W" }, { "start" : 1004, "end" : 1004, "residue" : "S" }, { "start" : 1071, "end" : 1071, "residue" : "E" }, { "start" : 935, "end" : 935, "residue" : "F" }, { "start" : 1011, "end" : 1011, "residue" : "N" }, { "start" : 1056, "end" : 1056, "residue" : "Y" }, { "start" : 1070, "end" : 1070, "residue" : "K" }, { "start" : 885, "end" : 885, "residue" : "F" }, { "start" : 1048, "end" : 1048, "residue" : "V" }, { "start" : 1074, "end" : 1074, "residue" : "A" } ] } ], "evalue" : 3.32943E-51, "score" : 178.382, "location-fragments" : [ { "start" : 828, "end" : 1099, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd15042" }, { "signature" : { "accession" : "PS50259", "name" : "G_PROTEIN_RECEP_F3_4", "description" : "G-protein coupled receptors family 3 profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR017978", "name" : "GPCR_3_C", "description" : "GPCR family 3, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "G protein-coupled receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004930" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "G protein-coupled receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007186" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1010, "end" : 1098, "score" : 11.566, "alignment" : "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------YNTFLLILCIITAPFIYKSRRNYNEGLYLTIVVIFLAIVWFVWISIYQFYDPSTTGIPNIKEMaalsglVASATGVLILIFIPRTYLML---------------", "location-fragments" : [ { "start" : 1010, "end" : 1098, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50259" }, { "signature" : { "accession" : "G3DSA:3.40.50.2300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 120, "hmmStart" : 5, "hmmEnd" : 82, "hmmLength" : 294, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-7, "score" : 32.0, "envelopeStart" : 35, "envelopeEnd" : 120, "postProcessed" : true, "location-fragments" : [ { "start" : 35, "end" : 120, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-8, "score" : 33.9, "model-ac" : "4xaqB01" } ], "xref" : [ { "name" : "XP_018909910.1 PREDICTED: uncharacterized protein LOC109039037 [Bemisia tabaci]", "id" : "XP_018909910.1" } ] },{ "sequence" : "MRDPPGPSVSLIDDAVDVDEDVPVPTNTRYEYSNRSTFAQVLATIVQSWLLIDNGLMKAVPTLILGSLHDNPNEPLDMNDDQASWFGAIPYICTPITSFASGIFQEKFGRKGSMILVNIPIFVAWILLYVAESIAAFYTVAVIMGLSIGLSEAPLSCYIGETSEPHLRGTLATIMSTAMIIGYFIMYTLGYFFDWRTAALISSAFPIVTFVLMTPIPESSTWLIGRSRFKDAKKSLRWLRGWVTAEAVEEEYQSLLSNNRDPIRKKPSESTLQERGPEQEDYGFFRTQYQTLMNDNIMLPLRLVLITSFIGYVAVLRGMTPYLIGELNALSTPIDAKLVLIITQILFLLGAAADMMFLQGLGKRKIALFSHAIAAVCLLGIGFYAFHLQASAVYYPHLAWLPVIFLMVINFLGGFSLQVLPWQLMCEVFPRVGRGLATGISAAWTHLVISLLIKSYLYIKAWIGLGGVMYLYGTITAFGVVYFYLHLPETEGKSLKQIETYFTSNHDRKEKFEVEK", "md5" : "dfc00cdae8ce13bb029d175db8050294", "matches" : [ { "signature" : { "accession" : "PTHR23500", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 395, "end" : 507, "hmmStart" : 535, "hmmEnd" : 647, "hmmLength" : 950, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 387, "envelopeEnd" : 515, "location-fragments" : [ { "start" : 395, "end" : 507, "dc-status" : "CONTINUOUS" } ] }, { "start" : 35, "end" : 390, "hmmStart" : 58, "hmmEnd" : 409, "hmmLength" : 950, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 398, "location-fragments" : [ { "start" : 35, "end" : 390, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-86, "familyName" : "", "score" : 292.5, "model-ac" : "PTHR23500" }, { "signature" : { "accession" : "cd17358", "name" : "MFS_GLUT6_8_Class3_like", "description" : "MFS_GLUT6_8_Class3_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 67, "end" : 497, "sites" : [ { "description" : "chemical substrate binding pocket", "numLocations" : 19, "siteLocations" : [ { "start" : 179, "end" : 179, "residue" : "M" }, { "start" : 308, "end" : 308, "residue" : "S" }, { "start" : 312, "end" : 312, "residue" : "Y" }, { "start" : 418, "end" : 418, "residue" : "Q" }, { "start" : 446, "end" : 446, "residue" : "H" }, { "start" : 449, "end" : 449, "residue" : "I" }, { "start" : 307, "end" : 307, "residue" : "T" }, { "start" : 183, "end" : 183, "residue" : "Y" }, { "start" : 180, "end" : 180, "residue" : "I" }, { "start" : 313, "end" : 313, "residue" : "V" }, { "start" : 413, "end" : 413, "residue" : "G" }, { "start" : 316, "end" : 316, "residue" : "L" }, { "start" : 347, "end" : 347, "residue" : "F" }, { "start" : 414, "end" : 414, "residue" : "G" }, { "start" : 417, "end" : 417, "residue" : "L" }, { "start" : 445, "end" : 445, "residue" : "T" }, { "start" : 176, "end" : 176, "residue" : "S" }, { "start" : 422, "end" : 422, "residue" : "W" }, { "start" : 317, "end" : 317, "residue" : "R" } ] } ], "evalue" : 4.98771E-68, "score" : 223.221, "location-fragments" : [ { "start" : 67, "end" : 497, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd17358" }, { "signature" : { "accession" : "PF00083", "name" : "Sugar_tr", "description" : "Sugar (and other) transporter", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005828", "name" : "MFS_sugar_transport-like", "description" : "Major facilitator, sugar transporter-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 79, "end" : 502, "hmmStart" : 41, "hmmEnd" : 452, "hmmLength" : 452, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 8.2E-45, "score" : 153.5, "envelopeStart" : 30, "envelopeEnd" : 502, "postProcessed" : true, "location-fragments" : [ { "start" : 79, "end" : 502, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.4E-45, "score" : 153.8, "model-ac" : "PF00083" }, { "signature" : { "accession" : "PTHR23500:SF3", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 395, "end" : 507, "hmmStart" : 535, "hmmEnd" : 647, "hmmLength" : 950, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 387, "envelopeEnd" : 515, "location-fragments" : [ { "start" : 395, "end" : 507, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-86, "familyName" : "", "score" : 292.5, "model-ac" : "PTHR23500:SF3" }, { "signature" : { "accession" : "G3DSA:1.20.1250.20", "name" : "MFS general substrate transporter like domains", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 28, "end" : 507, "hmmStart" : 11, "hmmEnd" : 476, "hmmLength" : 480, "hmmBounds" : "COMPLETE", "evalue" : 9.8E-71, "score" : 240.8, "envelopeStart" : 28, "envelopeEnd" : 507, "postProcessed" : true, "location-fragments" : [ { "start" : 28, "end" : 507, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.5E-71, "score" : 241.2, "model-ac" : "4ybqA00" }, { "signature" : { "accession" : "PS00217", "name" : "SUGAR_TRANSPORT_2", "description" : "Sugar transport proteins signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR005829", "name" : "Sugar_transporter_CS", "description" : "Sugar transporter, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 143, "end" : 168, "level" : "STRONG", "cigarAlignment" : "1M1I3M1I2M7I1M2I1M6I1M", "alignment" : "ImGLSiGLseaplscYigEtsephlR", "location-fragments" : [ { "start" : 143, "end" : 168, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00217" }, { "signature" : { "accession" : "SSF103473", "name" : "MFS general substrate transporter", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036259", "name" : "MFS_trans_sf", "description" : "MFS transporter superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 40, "end" : 499, "hmmLength" : 447, "location-fragments" : [ { "start" : 279, "end" : 499, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 40, "end" : 243, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 6.15E-45, "model-ac" : "0042501" }, { "signature" : { "accession" : "PS50850", "name" : "MFS", "description" : "Major facilitator superfamily (MFS) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR020846", "name" : "MFS_dom", "description" : "Major facilitator superfamily domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 39, "end" : 491, "score" : 21.225, "alignment" : "AQVLATIVQSWLLIDNGLMkavpTLILGSLHDNPNEPLdmndDQASWFGAIPYICTPITSFASGIFQEKFGRKGSMILVNIPIFVAWILLYVAESIAAFYTVAVIMGLSIGLSEAPLSCYIGETSEPHLRGTLATI----MSTAMIIGYFIMYTLGYFFDWRTAALISSAFPIVTFVLM-TPIPESSTWligrsrfkdakkslrwlrgwvtaeaveeeyqsllsnnrdpirkkpsesTLQERGPEQEDYGFFRTQYQTLMNDNimLPLRLVLITSFIG---YVAVLRGMTPYLIGELNALSTPIDAKLVLIITQILFLLGAAADMMFLQGLGKRKIALFSHAIAAVCLLGIGFYAFHLQasavyyphlaWLPVIFLMVINFLGGFSLQVLPWQLMCEVFPRVGRGLATGISAAWTHLVISLLIKSYLYIKAwiGLGG--VMYLYGTITAFGVVYFYLHLPETE", "location-fragments" : [ { "start" : 39, "end" : 491, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50850" }, { "signature" : { "accession" : "PTHR23500:SF3", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 390, "hmmStart" : 58, "hmmEnd" : 409, "hmmLength" : 950, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 398, "location-fragments" : [ { "start" : 35, "end" : 390, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-86, "familyName" : "", "score" : 292.5, "model-ac" : "PTHR23500:SF3" } ], "xref" : [ { "name" : "XP_018909635.1 PREDICTED: facilitated trehalose transporter Tret1-2 homolog [Bemisia tabaci]", "id" : "XP_018909635.1" } ] },{ "sequence" : "MELLEFSNSWLLNLCRRNGFRISNFLVLICLCHLIEYSESSTSLTFNDILPEDPKLYDKMRPPKKDGNPTIVFFHVTVMGLDSIDESSMTYAADIFFAQSWKDNRLRLPENMTSEYRLLEVDWLKNMWRPDSFFKNAKAVTFQTMTIPNHYVWLYKDKTILYMVKLTLTLSCAMNFMIYPHDTQECKLQMESLSHTTDDMVFQWDPEVPLVVGEDIELPQLQLVKNRTADCTQVYSTGNFTCLEVVFELKRRLGYYLFHTYIPTCLIVIMSWISFWIKPEAAPARVTLGVTSLLTLSTQHAKSQASLPPVSYLKAVDAFMSTCTVFVFMALMEYCLVNIVLGDSDLPPKPQPEPAKPDKLFELAAKENARLLTGQPTPQQRPNPAAALAQKQRTRAINIDRFSRVFFPLLFTILNCTYWFMFAEFL", "md5" : "ee501a4c87a3c353dbbffd0effe3fedc", "matches" : [ { "signature" : { "accession" : "cd18992", "name" : "LGIC_ECD_HisCl", "description" : "LGIC_ECD_HisCl", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 69, "end" : 252, "sites" : [ { "description" : "pentamer interface", "numLocations" : 33, "siteLocations" : [ { "start" : 83, "end" : 83, "residue" : "S" }, { "start" : 149, "end" : 149, "residue" : "N" }, { "start" : 131, "end" : 131, "residue" : "D" }, { "start" : 135, "end" : 135, "residue" : "K" }, { "start" : 140, "end" : 140, "residue" : "V" }, { "start" : 219, "end" : 219, "residue" : "P" }, { "start" : 80, "end" : 80, "residue" : "G" }, { "start" : 138, "end" : 138, "residue" : "K" }, { "start" : 217, "end" : 217, "residue" : "E" }, { "start" : 166, "end" : 166, "residue" : "L" }, { "start" : 89, "end" : 89, "residue" : "M" }, { "start" : 167, "end" : 167, "residue" : "T" }, { "start" : 143, "end" : 143, "residue" : "Q" }, { "start" : 146, "end" : 146, "residue" : "T" }, { "start" : 96, "end" : 96, "residue" : "F" }, { "start" : 98, "end" : 98, "residue" : "A" }, { "start" : 153, "end" : 153, "residue" : "W" }, { "start" : 142, "end" : 142, "residue" : "F" }, { "start" : 132, "end" : 132, "residue" : "S" }, { "start" : 220, "end" : 220, "residue" : "Q" }, { "start" : 145, "end" : 145, "residue" : "M" }, { "start" : 194, "end" : 194, "residue" : "S" }, { "start" : 88, "end" : 88, "residue" : "S" }, { "start" : 119, "end" : 119, "residue" : "L" }, { "start" : 134, "end" : 134, "residue" : "F" }, { "start" : 151, "end" : 151, "residue" : "Y" }, { "start" : 137, "end" : 137, "residue" : "A" }, { "start" : 165, "end" : 165, "residue" : "K" }, { "start" : 133, "end" : 133, "residue" : "F" }, { "start" : 147, "end" : 147, "residue" : "I" }, { "start" : 252, "end" : 252, "residue" : "R" }, { "start" : 92, "end" : 92, "residue" : "A" }, { "start" : 193, "end" : 193, "residue" : "L" } ] }, { "description" : "ligand binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 153, "end" : 153, "residue" : "W" }, { "start" : 151, "end" : 151, "residue" : "Y" }, { "start" : 77, "end" : 77, "residue" : "T" }, { "start" : 96, "end" : 96, "residue" : "F" }, { "start" : 161, "end" : 161, "residue" : "L" }, { "start" : 98, "end" : 98, "residue" : "A" } ] } ], "evalue" : 6.57933E-135, "score" : 382.734, "location-fragments" : [ { "start" : 69, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18992" }, { "signature" : { "accession" : "cd19049", "name" : "LGIC_TM_anion", "description" : "LGIC_TM_anion", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 255, "end" : 419, "sites" : [ { "description" : "pentamer interface", "numLocations" : 35, "siteLocations" : [ { "start" : 276, "end" : 276, "residue" : "W" }, { "start" : 269, "end" : 269, "residue" : "I" }, { "start" : 283, "end" : 283, "residue" : "P" }, { "start" : 312, "end" : 312, "residue" : "Y" }, { "start" : 267, "end" : 267, "residue" : "I" }, { "start" : 404, "end" : 404, "residue" : "R" }, { "start" : 335, "end" : 335, "residue" : "C" }, { "start" : 259, "end" : 259, "residue" : "H" }, { "start" : 313, "end" : 313, "residue" : "L" }, { "start" : 328, "end" : 328, "residue" : "F" }, { "start" : 304, "end" : 304, "residue" : "Q" }, { "start" : 281, "end" : 281, "residue" : "A" }, { "start" : 270, "end" : 270, "residue" : "M" }, { "start" : 294, "end" : 294, "residue" : "L" }, { "start" : 290, "end" : 290, "residue" : "V" }, { "start" : 295, "end" : 295, "residue" : "T" }, { "start" : 301, "end" : 301, "residue" : "A" }, { "start" : 266, "end" : 266, "residue" : "L" }, { "start" : 255, "end" : 255, "residue" : "Y" }, { "start" : 288, "end" : 288, "residue" : "L" }, { "start" : 305, "end" : 305, "residue" : "A" }, { "start" : 278, "end" : 278, "residue" : "K" }, { "start" : 287, "end" : 287, "residue" : "T" }, { "start" : 258, "end" : 258, "residue" : "F" }, { "start" : 273, "end" : 273, "residue" : "I" }, { "start" : 282, "end" : 282, "residue" : "A" }, { "start" : 286, "end" : 286, "residue" : "V" }, { "start" : 291, "end" : 291, "residue" : "T" }, { "start" : 338, "end" : 338, "residue" : "N" }, { "start" : 277, "end" : 277, "residue" : "I" }, { "start" : 324, "end" : 324, "residue" : "T" }, { "start" : 302, "end" : 302, "residue" : "K" }, { "start" : 331, "end" : 331, "residue" : "L" }, { "start" : 339, "end" : 339, "residue" : "I" }, { "start" : 284, "end" : 284, "residue" : "A" } ] } ], "evalue" : 4.77649E-50, "score" : 163.007, "location-fragments" : [ { "start" : 255, "end" : 419, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd19049" }, { "signature" : { "accession" : "SSF63712", "name" : "Nicotinic receptor ligand binding domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036734", "name" : "Neur_chan_lig-bd_sf", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 56, "end" : 252, "hmmLength" : 205, "location-fragments" : [ { "start" : 56, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.45E-45, "model-ac" : "0038932" }, { "signature" : { "accession" : "PTHR18945", "name" : "NEUROTRANSMITTER GATED ION CHANNEL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 41, "end" : 403, "hmmStart" : 5, "hmmEnd" : 356, "hmmLength" : 359, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 24, "envelopeEnd" : 407, "location-fragments" : [ { "start" : 41, "end" : 403, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.0E-169, "familyName" : "HISTAMINE-GATED CHLORIDE CHANNEL ALPHA1 SUBUNIT", "score" : 563.8, "model-ac" : "PTHR18945" }, { "signature" : { "accession" : "G3DSA:2.70.170.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036734", "name" : "Neur_chan_lig-bd_sf", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 250, "hmmStart" : 16, "hmmEnd" : 218, "hmmLength" : 219, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.6E-62, "score" : 210.5, "envelopeStart" : 37, "envelopeEnd" : 252, "postProcessed" : true, "location-fragments" : [ { "start" : 37, "end" : 250, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-62, "score" : 210.9, "model-ac" : "5cfbA01" }, { "signature" : { "accession" : "PF02932", "name" : "Neur_chan_memb", "description" : "Neurotransmitter-gated ion-channel transmembrane region", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006029", "name" : "Neurotrans-gated_channel_TM", "description" : "Neurotransmitter-gated ion-channel transmembrane domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 260, "end" : 341, "hmmStart" : 1, "hmmEnd" : 82, "hmmLength" : 238, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 9.6E-23, "score" : 81.5, "envelopeStart" : 260, "envelopeEnd" : 361, "postProcessed" : true, "location-fragments" : [ { "start" : 260, "end" : 341, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-26, "score" : 91.8, "model-ac" : "PF02932" }, { "signature" : { "accession" : "PR00253", "name" : "GABAARECEPTR", "description" : "Gamma-aminobutyric acid A (GABAA) receptor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR006028", "name" : "GABAA/Glycine_rcpt", "description" : "Gamma-aminobutyric acid A receptor/Glycine receptor alpha", "type" : "FAMILY", "goXRefs" : [ { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 256, "end" : 276, "pvalue" : 8.48E-11, "score" : 52.51, "motifNumber" : 1, "location-fragments" : [ { "start" : 256, "end" : 276, "dc-status" : "CONTINUOUS" } ] }, { "start" : 316, "end" : 337, "pvalue" : 2.21E-10, "score" : 43.81, "motifNumber" : 3, "location-fragments" : [ { "start" : 316, "end" : 337, "dc-status" : "CONTINUOUS" } ] }, { "start" : 402, "end" : 422, "pvalue" : 1.9E-8, "score" : 41.17, "motifNumber" : 4, "location-fragments" : [ { "start" : 402, "end" : 422, "dc-status" : "CONTINUOUS" } ] }, { "start" : 282, "end" : 303, "pvalue" : 2.18E-11, "score" : 46.14, "motifNumber" : 2, "location-fragments" : [ { "start" : 282, "end" : 303, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.6E-33, "graphscan" : "IIII", "model-ac" : "PR00253" }, { "signature" : { "accession" : "PF02931", "name" : "Neur_chan_LBD", "description" : "Neurotransmitter-gated ion-channel ligand binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006202", "name" : "Neur_chan_lig-bd", "description" : "Neurotransmitter-gated ion-channel ligand-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" }, { "name" : "extracellular ligand-gated ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005230" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 57, "end" : 252, "hmmStart" : 12, "hmmEnd" : 216, "hmmLength" : 217, "hmmBounds" : "INCOMPLETE", "evalue" : 7.5E-33, "score" : 113.8, "envelopeStart" : 45, "envelopeEnd" : 253, "postProcessed" : true, "location-fragments" : [ { "start" : 57, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-33, "score" : 114.2, "model-ac" : "PF02931" }, { "signature" : { "accession" : "PTHR18945:SF598", "name" : "HISTAMINE-GATED CHLORIDE CHANNEL ALPHA1 SUBUNIT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 41, "end" : 403, "hmmStart" : 5, "hmmEnd" : 356, "hmmLength" : 359, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 24, "envelopeEnd" : 407, "location-fragments" : [ { "start" : 41, "end" : 403, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.0E-169, "familyName" : "HISTAMINE-GATED CHLORIDE CHANNEL ALPHA1 SUBUNIT", "score" : 563.8, "model-ac" : "PTHR18945:SF598" }, { "signature" : { "accession" : "SSF90112", "name" : "Neurotransmitter-gated ion-channel transmembrane pore", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036719", "name" : "Neuro-gated_channel_TM_sf", "description" : "Neurotransmitter-gated ion-channel transmembrane domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "ion transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006811" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 254, "end" : 422, "hmmLength" : 250, "location-fragments" : [ { "start" : 254, "end" : 422, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-41, "model-ac" : "0041811" }, { "signature" : { "accession" : "PS00236", "name" : "NEUROTR_ION_CHANNEL", "description" : "Neurotransmitter-gated ion-channels signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018000", "name" : "Neurotransmitter_ion_chnl_CS", "description" : "Neurotransmitter-gated ion-channel, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 172, "end" : 186, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I1M2I2M1I1M3I1M", "alignment" : "CaMnFmiYPhDtqeC", "location-fragments" : [ { "start" : 172, "end" : 186, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00236" }, { "signature" : { "accession" : "PR00252", "name" : "NRIONCHANNEL", "description" : "Neurotransmitter-gated ion channel family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 247, "end" : 259, "pvalue" : 5.42E-5, "score" : 32.96, "motifNumber" : 4, "location-fragments" : [ { "start" : 247, "end" : 259, "dc-status" : "CONTINUOUS" } ] }, { "start" : 172, "end" : 186, "pvalue" : 5.16E-5, "score" : 38.25, "motifNumber" : 3, "location-fragments" : [ { "start" : 172, "end" : 186, "dc-status" : "CONTINUOUS" } ] }, { "start" : 92, "end" : 108, "pvalue" : 2.37E-4, "score" : 33.38, "motifNumber" : 1, "location-fragments" : [ { "start" : 92, "end" : 108, "dc-status" : "CONTINUOUS" } ] }, { "start" : 126, "end" : 137, "pvalue" : 9.03E-4, "score" : 39.78, "motifNumber" : 2, "location-fragments" : [ { "start" : 126, "end" : 137, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.9E-10, "graphscan" : "IIII", "model-ac" : "PR00252" }, { "signature" : { "accession" : "TIGR00860", "name" : "TIGR00860", "description" : "LIC: cation transporter family protein", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR006201", "name" : "Neur_channel", "description" : "Neurotransmitter-gated ion-channel", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane signaling receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004888" }, { "name" : "ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0034220" }, { "name" : "ion channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005216" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 39, "end" : 341, "hmmStart" : 21, "hmmEnd" : 331, "hmmLength" : 462, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-90, "score" : 302.0, "envelopeStart" : 14, "envelopeEnd" : 351, "postProcessed" : false, "location-fragments" : [ { "start" : 39, "end" : 341, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-95, "score" : 318.0, "model-ac" : "TIGR00860" } ], "xref" : [ { "name" : "XP_018909663.1 PREDICTED: glycine receptor subunit alpha-2-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909663.1" } ] },{ "sequence" : "MASASSTSARSLFAESKSRLAAKIEINLCNIASVSRHILKGSRSSDILMGSAKSFAAMDGSIDAIESNLHKLQGIESNLRNQHQAIENSLHYVEEVKEQVRAMQR", "md5" : "5342ccc8708dbae86e64f9bf4a559d68", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 62, "end" : 82, "location-fragments" : [ { "start" : 62, "end" : 82, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF16088", "name" : "BORCS7", "description" : "BLOC-1-related complex sub-unit 7", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR032143", "name" : "BORCS7", "description" : "BLOC-1-related complex subunit 7", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 103, "hmmStart" : 1, "hmmEnd" : 103, "hmmLength" : 103, "hmmBounds" : "COMPLETE", "evalue" : 9.5E-28, "score" : 96.5, "envelopeStart" : 1, "envelopeEnd" : 103, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 103, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-28, "score" : 96.6, "model-ac" : "PF16088" }, { "signature" : { "accession" : "PTHR31397", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR032143", "name" : "BORCS7", "description" : "BLOC-1-related complex subunit 7", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 105, "hmmStart" : 1, "hmmEnd" : 105, "hmmLength" : 105, "hmmBounds" : "COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 105, "location-fragments" : [ { "start" : 1, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-24, "familyName" : "FAMILY NOT NAMED", "score" : 88.3, "model-ac" : "PTHR31397" } ], "xref" : [ { "name" : "XP_018910306.1 PREDICTED: uncharacterized protein LOC109039329 [Bemisia tabaci]", "id" : "XP_018910306.1" } ] },{ "sequence" : "MIFISFLVLPLLTSPCIEAFKILVFYPFPSHSHQSAIMALTERLVRDGHELFVISPNVVPGLTGHVNYTHVDLSFSYQYIPDENNAEDAGVNLQRIWSKWELPLLWKALARIARKQLQSETFLQFDRRVAAERINFDLFIVEFYYLPFSCAILRNYTKSAPIITLSSMPTDFLTEETLGSYEHLSYSPSLFSDYTDRMSLLQKLDNWISHYYIVSKLNEELDISVRRHCKEAYGPEYEMIADGCKSRISLSLIASNAMYGFPRLLGPNVIETGPLHIRIPKELPQDLQNWLDGAEKGVIYFSLGCNLRGKSLNEDVRANFLKVFAQLQPLGYRVLWKWELDEKIPGQSSNILAQKWIPQQSVLAHPKIKVFITQGGLQSFQEAVHHGVPMVGIPWFVDQGFNVAKMVDAGIGVKLLPKNLHSYEDIKLALETVLHDKKYSDNMKRHSAISHDLTSRAMDRAVFWVEHVARHKGASHLRPSAADASLFEFFCFDIISVILCFGLTIVYFLFKLLVGIVFKKIGTKIKLS", "md5" : "ce13c71e2615995e87b2a263cf593287", "matches" : [ { "signature" : { "accession" : "cd03784", "name" : "GT1_Gtf-like", "description" : "GT1_Gtf-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 449, "sites" : [ { "description" : "acceptor substrate-binding pocket", "numLocations" : 1, "siteLocations" : [ { "start" : 33, "end" : 33, "residue" : "H" } ] }, { "description" : "TDP-binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 379, "end" : 379, "residue" : "S" }, { "start" : 374, "end" : 374, "residue" : "Q" }, { "start" : 376, "end" : 376, "residue" : "G" }, { "start" : 307, "end" : 307, "residue" : "L" }, { "start" : 378, "end" : 378, "residue" : "Q" }, { "start" : 32, "end" : 32, "residue" : "S" } ] }, { "description" : "active site", "numLocations" : 14, "siteLocations" : [ { "start" : 35, "end" : 35, "residue" : "S" }, { "start" : 196, "end" : 196, "residue" : "D" }, { "start" : 249, "end" : 249, "residue" : "S" }, { "start" : 199, "end" : 199, "residue" : "S" }, { "start" : 307, "end" : 307, "residue" : "L" }, { "start" : 379, "end" : 379, "residue" : "S" }, { "start" : 33, "end" : 33, "residue" : "H" }, { "start" : 382, "end" : 382, "residue" : "E" }, { "start" : 200, "end" : 200, "residue" : "L" }, { "start" : 374, "end" : 374, "residue" : "Q" }, { "start" : 376, "end" : 376, "residue" : "G" }, { "start" : 204, "end" : 204, "residue" : "L" }, { "start" : 378, "end" : 378, "residue" : "Q" }, { "start" : 32, "end" : 32, "residue" : "S" } ] } ], "evalue" : 1.05998E-49, "score" : 174.277, "location-fragments" : [ { "start" : 24, "end" : 449, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd03784" }, { "signature" : { "accession" : "PS00375", "name" : "UDPGT", "description" : "UDP-glycosyltransferases signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR035595", "name" : "UDP_glycos_trans_CS", "description" : "UDP-glycosyltransferase family, conserved site", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Glucuronidation", "databaseName" : "Reactome", "id" : "R-HSA-156588" } ] } }, "locations" : [ { "start" : 356, "end" : 399, "level" : "STRONG", "cigarAlignment" : "1M2I1M2I2M6I7M2I1M3I2M4I2M3I1M3I2M", "alignment" : "WipQqsVLahpkikVFITQGGlqSfqeAVhhgvPMvgiPwfvDQ", "location-fragments" : [ { "start" : 356, "end" : 399, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00375" }, { "signature" : { "accession" : "SSF53756", "name" : "UDP-Glycosyltransferase/glycogen phosphorylase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 21, "end" : 477, "hmmLength" : 471, "location-fragments" : [ { "start" : 21, "end" : 477, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.91E-84, "model-ac" : "0054711" }, { "signature" : { "accession" : "G3DSA:3.40.50.2000", "name" : "Glycogen Phosphorylase B;", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 278, "end" : 452, "hmmStart" : 5, "hmmEnd" : 167, "hmmLength" : 170, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-41, "score" : 142.8, "envelopeStart" : 278, "envelopeEnd" : 452, "postProcessed" : true, "location-fragments" : [ { "start" : 278, "end" : 452, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-41, "score" : 143.3, "model-ac" : "2o6lB00" }, { "signature" : { "accession" : "PF00201", "name" : "UDPGT", "description" : "UDP-glucoronosyl and UDP-glucosyl transferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002213", "name" : "UDP_glucos_trans", "description" : "UDP-glucuronosyl/UDP-glucosyltransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "UDP-glycosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008194" } ], "pathwayXRefs" : [ { "name" : "Glucuronidation", "databaseName" : "Reactome", "id" : "R-HSA-156588" } ] } }, "locations" : [ { "start" : 30, "end" : 522, "hmmStart" : 9, "hmmEnd" : 494, "hmmLength" : 499, "hmmBounds" : "INCOMPLETE", "evalue" : 3.6E-72, "score" : 243.8, "envelopeStart" : 21, "envelopeEnd" : 527, "postProcessed" : true, "location-fragments" : [ { "start" : 30, "end" : 522, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-72, "score" : 244.2, "model-ac" : "PF00201" }, { "signature" : { "accession" : "PTHR11926", "name" : "GLUCOSYL/GLUCURONOSYL TRANSFERASES", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 267, "end" : 403, "hmmStart" : 41, "hmmEnd" : 125, "hmmLength" : 134, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 25, "envelopeEnd" : 507, "location-fragments" : [ { "start" : 267, "end" : 403, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.2E-18, "familyName" : "GLUCOSYL/GLUCURONOSYL TRANSFERASES", "score" : 67.5, "model-ac" : "PTHR11926" } ], "xref" : [ { "name" : "XP_018909894.1 PREDICTED: UDP-glucuronosyltransferase 2B9-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909894.1" } ] },{ "sequence" : "MITSKYLLLIIFYLHCVRCSLKPETKHDDILPPCSSCKVLVESFMKGVKRTSRENFAGGDAAWEEEKLGTYATSEVRLIEIQEKLCSEVGRGKDQCLTLSETHEALLEDWWFNEQKVSPDLKQWLCVDLLKVCCPAGHFGADCQPCPGFPKVCFGNGKCKGDGTRKGNGACICDAGYTGEYCDACGPGYYQSYKDDDKLLCSKCHPACSGNCTEAGTKGCEACNEGWAMTAENGCVDVNECVLPDVCKHNQFCVNEEGNYSCIECDAACSGCYGDGPDMCIKCAPGYFLQDNFCVVEDFFDGSSNHLCHLSDYWSFLRHDSYCPKL", "md5" : "4cb236f6848baa43de307c81f45f5e15", "matches" : [ { "signature" : { "accession" : "cd00064", "name" : "FU", "description" : "FU", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR006212", "name" : "Furin_repeat", "description" : "Furin-like repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 264, "end" : 297, "sites" : [ ], "evalue" : 2.38523E-4, "score" : 36.3428, "location-fragments" : [ { "start" : 264, "end" : 297, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00064" }, { "signature" : { "accession" : "PS01248", "name" : "EGF_LAM_1", "description" : "Laminin-type EGF-like (LE) domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR002049", "name" : "Laminin_EGF", "description" : "Laminin EGF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 171, "end" : 204, "level" : "STRONG", "cigarAlignment" : "1M1I1M5I1M2I1M2I1M4I1M13I1M", "alignment" : "CiCdagytGeyCdaCgpgyYqsykdddkllcskC", "location-fragments" : [ { "start" : 171, "end" : 204, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01248" }, { "signature" : { "accession" : "PS50026", "name" : "EGF_3", "description" : "EGF-like domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 142, "end" : 183, "score" : 10.747, "alignment" : "DCQPCPgfpKVCFGNGKCKGDGTrKGNGACICDAGYTGEYCD", "location-fragments" : [ { "start" : 142, "end" : 183, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50026" }, { "signature" : { "accession" : "SM00261", "name" : "furin_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006212", "name" : "Furin_repeat", "description" : "Furin-like repeat", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 198, "end" : 253, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 2.4, "score" : 17.1, "location-fragments" : [ { "start" : 198, "end" : 253, "dc-status" : "CONTINUOUS" } ] }, { "start" : 259, "end" : 301, "hmmStart" : 1, "hmmEnd" : 48, "hmmLength" : 48, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-7, "score" : 39.6, "location-fragments" : [ { "start" : 259, "end" : 301, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-12, "score" : 56.7, "model-ac" : "SM00261" }, { "signature" : { "accession" : "PTHR24034", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 296, "hmmStart" : 22, "hmmEnd" : 290, "hmmLength" : 353, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 316, "location-fragments" : [ { "start" : 25, "end" : 296, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-65, "familyName" : "CYSTEINE-RICH WITH EGF-LIKE DOMAIN PROTEIN 2", "score" : 223.6, "model-ac" : "PTHR24034" }, { "signature" : { "accession" : "PTHR24034:SF110", "name" : "CYSTEINE-RICH WITH EGF-LIKE DOMAIN PROTEIN 2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 296, "hmmStart" : 22, "hmmEnd" : 290, "hmmLength" : 353, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 316, "location-fragments" : [ { "start" : 25, "end" : 296, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-65, "familyName" : "CYSTEINE-RICH WITH EGF-LIKE DOMAIN PROTEIN 2", "score" : 223.6, "model-ac" : "PTHR24034:SF110" }, { "signature" : { "accession" : "PS01187", "name" : "EGF_CA", "description" : "Calcium-binding EGF-like domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018097", "name" : "EGF_Ca-bd_CS", "description" : "EGF-like calcium-binding, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "calcium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005509" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 237, "end" : 262, "level" : "STRONG", "cigarAlignment" : "1M1I3M5I1M5I1M1I1M4I1M1I1M", "alignment" : "DvNECvlpdvCkhnqfCvNeegnYsC", "location-fragments" : [ { "start" : 237, "end" : 262, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01187" }, { "signature" : { "accession" : "PS00022", "name" : "EGF_1", "description" : "EGF-like domain signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000742", "name" : "EGF-like_dom", "description" : "EGF-like domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 171, "end" : 182, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I1M2I2M1I1M", "alignment" : "CiCdaGytGEyC", "location-fragments" : [ { "start" : 171, "end" : 182, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00022" }, { "signature" : { "accession" : "cd00054", "name" : "EGF_CA", "description" : "EGF_CA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 237, "end" : 263, "sites" : [ { "description" : "Ca2+ binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 237, "end" : 237, "residue" : "D" }, { "start" : 240, "end" : 240, "residue" : "E" }, { "start" : 255, "end" : 255, "residue" : "N" } ] } ], "evalue" : 0.0019314, "score" : 33.379, "location-fragments" : [ { "start" : 237, "end" : 263, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00054" }, { "signature" : { "accession" : "SSF57184", "name" : "Growth factor receptor domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009030", "name" : "Growth_fac_rcpt_cys_sf", "description" : "Growth factor receptor cysteine-rich domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 179, "end" : 296, "hmmLength" : 145, "location-fragments" : [ { "start" : 179, "end" : 296, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.13E-14, "model-ac" : "0048103" } ], "xref" : [ { "name" : "XP_018909877.1 PREDICTED: cysteine-rich with EGF-like domain protein 2 isoform X2 [Bemisia tabaci]", "id" : "XP_018909877.1" } ] },{ "sequence" : "MVAMDPGGQERRPQRSQSVLQKMRNVIRVADSDPCLDLGEQKIQRKNWEEIAEKSALCQAAFDDLMSLPDDLKGPCLGACRAECQLKKKKSGQWFQCTVLKPSHCFCTPSTKPFAFCASSVALEIQRNQDAPAPGRTLYQALSANRRGGGGAN", "md5" : "9d3527582573fe5299d9ad66087fcd95", "matches" : [ ], "xref" : [ { "name" : "XP_018909948.1 PREDICTED: uncharacterized protein LOC109039070 isoform X2 [Bemisia tabaci]", "id" : "XP_018909948.1" } ] },{ "sequence" : "MLASNELIKKSILLSSKMFVRHGSLVFNKAFVNGSFIDADSRKQFNVVNPATGEVITPVPDMDVSDVEKTITLAHDAFKEWKNTTAKERGIVLRKWYNLLVEHQEELARIITSEAGKPYKESLGEVAYGNSFIDWFAEESRRINGEVIPSPVKSKRIVLIKQPIGVVGLITPWNFPHAMITRKAGAALAAGCTCVVKPAEDTPLTALALAALADQAGLPKGVLNVITCDRSNAPAVGKLLCESPLTAGISFTGSTAVGKILYQQCASGVKKVAFELGGNAPFIVFNSATIEKAVEGAIACKFRNSGQTCVSANRIFVQDKVFSQFVGALKEAMDKCLKIGKTEDCNVGPLINEAQMNKVSSLVDDAVSKGAKVLLGGKKAQSHGSLFYEPTLLTDVTPDMLCAKEEIFGPIAVCYKFKTEDEVIAAANDVRVGLAGYFYSNDIGQIWRVAEQLEVGMVGVNEGIISTAEAAFGGVKESGIGREGSHHGIDEFTDVKYICFGNLD", "md5" : "7b20a4a95e2bfdff9cd60c66fac9c2fd", "matches" : [ { "signature" : { "accession" : "cd07103", "name" : "ALDH_F5_SSADH_GabD", "description" : "ALDH_F5_SSADH_GabD", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 47, "end" : 500, "sites" : [ { "description" : "tetramerization interface", "numLocations" : 50, "siteLocations" : [ { "start" : 494, "end" : 494, "residue" : "D" }, { "start" : 145, "end" : 145, "residue" : "G" }, { "start" : 470, "end" : 470, "residue" : "A" }, { "start" : 138, "end" : 138, "residue" : "E" }, { "start" : 155, "end" : 155, "residue" : "K" }, { "start" : 143, "end" : 143, "residue" : "I" }, { "start" : 467, "end" : 467, "residue" : "T" }, { "start" : 461, "end" : 461, "residue" : "N" }, { "start" : 499, "end" : 499, "residue" : "C" }, { "start" : 142, "end" : 142, "residue" : "R" }, { "start" : 247, "end" : 247, "residue" : "A" }, { "start" : 456, "end" : 456, "residue" : "G" }, { "start" : 482, "end" : 482, "residue" : "R" }, { "start" : 450, "end" : 450, "residue" : "A" }, { "start" : 323, "end" : 323, "residue" : "S" }, { "start" : 149, "end" : 149, "residue" : "P" }, { "start" : 157, "end" : 157, "residue" : "I" }, { "start" : 144, "end" : 144, "residue" : "N" }, { "start" : 455, "end" : 455, "residue" : "V" }, { "start" : 263, "end" : 263, "residue" : "Q" }, { "start" : 459, "end" : 459, "residue" : "G" }, { "start" : 148, "end" : 148, "residue" : "I" }, { "start" : 94, "end" : 94, "residue" : "R" }, { "start" : 156, "end" : 156, "residue" : "R" }, { "start" : 259, "end" : 259, "residue" : "K" }, { "start" : 444, "end" : 444, "residue" : "G" }, { "start" : 448, "end" : 448, "residue" : "R" }, { "start" : 453, "end" : 453, "residue" : "L" }, { "start" : 460, "end" : 460, "residue" : "V" }, { "start" : 500, "end" : 500, "residue" : "F" }, { "start" : 327, "end" : 327, "residue" : "G" }, { "start" : 458, "end" : 458, "residue" : "V" }, { "start" : 162, "end" : 162, "residue" : "Q" }, { "start" : 139, "end" : 139, "residue" : "E" }, { "start" : 266, "end" : 266, "residue" : "A" }, { "start" : 495, "end" : 495, "residue" : "V" }, { "start" : 471, "end" : 471, "residue" : "A" }, { "start" : 372, "end" : 372, "residue" : "K" }, { "start" : 497, "end" : 497, "residue" : "Y" }, { "start" : 141, "end" : 141, "residue" : "R" }, { "start" : 498, "end" : 498, "residue" : "I" }, { "start" : 443, "end" : 443, "residue" : "I" }, { "start" : 441, "end" : 441, "residue" : "N" }, { "start" : 85, "end" : 85, "residue" : "T" }, { "start" : 135, "end" : 135, "residue" : "W" }, { "start" : 496, "end" : 496, "residue" : "K" }, { "start" : 477, "end" : 477, "residue" : "E" }, { "start" : 457, "end" : 457, "residue" : "M" }, { "start" : 146, "end" : 146, "residue" : "E" }, { "start" : 147, "end" : 147, "residue" : "V" } ] }, { "description" : "catalytic residues", "numLocations" : 4, "siteLocations" : [ { "start" : 306, "end" : 306, "residue" : "G" }, { "start" : 174, "end" : 174, "residue" : "N" }, { "start" : 275, "end" : 275, "residue" : "E" }, { "start" : 309, "end" : 309, "residue" : "C" } ] }, { "description" : "NAD(P) binding site", "numLocations" : 24, "siteLocations" : [ { "start" : 171, "end" : 171, "residue" : "T" }, { "start" : 254, "end" : 254, "residue" : "S" }, { "start" : 257, "end" : 257, "residue" : "V" }, { "start" : 406, "end" : 406, "residue" : "E" }, { "start" : 182, "end" : 182, "residue" : "R" }, { "start" : 261, "end" : 261, "residue" : "L" }, { "start" : 252, "end" : 252, "residue" : "T" }, { "start" : 173, "end" : 173, "residue" : "W" }, { "start" : 174, "end" : 174, "residue" : "N" }, { "start" : 277, "end" : 277, "residue" : "G" }, { "start" : 276, "end" : 276, "residue" : "L" }, { "start" : 408, "end" : 408, "residue" : "F" }, { "start" : 472, "end" : 472, "residue" : "F" }, { "start" : 309, "end" : 309, "residue" : "C" }, { "start" : 260, "end" : 260, "residue" : "I" }, { "start" : 434, "end" : 434, "residue" : "L" }, { "start" : 170, "end" : 170, "residue" : "I" }, { "start" : 197, "end" : 197, "residue" : "K" }, { "start" : 199, "end" : 199, "residue" : "A" }, { "start" : 172, "end" : 172, "residue" : "P" }, { "start" : 253, "end" : 253, "residue" : "G" }, { "start" : 251, "end" : 251, "residue" : "F" }, { "start" : 275, "end" : 275, "residue" : "E" }, { "start" : 200, "end" : 200, "residue" : "E" } ] } ], "evalue" : 0.0, "score" : 762.357, "location-fragments" : [ { "start" : 47, "end" : 500, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd07103" }, { "signature" : { "accession" : "PTHR43353:SF5", "name" : "SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 23, "end" : 503, "hmmStart" : 5, "hmmEnd" : 482, "hmmLength" : 483, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 18, "envelopeEnd" : 504, "location-fragments" : [ { "start" : 23, "end" : 503, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-224, "familyName" : "SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL", "score" : 749.2, "model-ac" : "PTHR43353:SF5" }, { "signature" : { "accession" : "SSF53720", "name" : "ALDH-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016161", "name" : "Ald_DH/histidinol_DH", "description" : "Aldehyde/histidinol dehydrogenase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" }, { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 18, "end" : 501, "hmmLength" : 516, "location-fragments" : [ { "start" : 18, "end" : 501, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.51E-162, "model-ac" : "0044574" }, { "signature" : { "accession" : "G3DSA:3.40.605.10", "name" : "Aldehyde Dehydrogenase; Chain A", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR016162", "name" : "Ald_DH_N", "description" : "Aldehyde dehydrogenase, N-terminal", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" }, { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 493, "hmmStart" : 2, "hmmEnd" : 450, "hmmLength" : 296, "hmmBounds" : "INCOMPLETE", "evalue" : 2.9E-176, "score" : 588.4, "envelopeStart" : 43, "envelopeEnd" : 493, "postProcessed" : true, "location-fragments" : [ { "start" : 44, "end" : 279, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 470, "end" : 493, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 2.4E-176, "score" : 588.7, "model-ac" : "2w8nA01" }, { "signature" : { "accession" : "G3DSA:3.40.309.10", "name" : "Aldehyde Dehydrogenase; Chain A", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR016163", "name" : "Ald_DH_C", "description" : "Aldehyde dehydrogenase, C-terminal", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016620" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 280, "end" : 469, "hmmStart" : 2, "hmmEnd" : 450, "hmmLength" : 191, "hmmBounds" : "INCOMPLETE", "evalue" : 2.9E-176, "score" : 588.4, "envelopeStart" : 43, "envelopeEnd" : 493, "postProcessed" : true, "location-fragments" : [ { "start" : 280, "end" : 469, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-176, "score" : 588.7, "model-ac" : "2w8nA02" }, { "signature" : { "accession" : "PF00171", "name" : "Aldedh", "description" : "Aldehyde dehydrogenase family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR015590", "name" : "Aldehyde_DH_dom", "description" : "Aldehyde dehydrogenase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" }, { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 498, "hmmStart" : 2, "hmmEnd" : 462, "hmmLength" : 462, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.6E-163, "score" : 544.5, "envelopeStart" : 36, "envelopeEnd" : 498, "postProcessed" : true, "location-fragments" : [ { "start" : 37, "end" : 498, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-163, "score" : 544.7, "model-ac" : "PF00171" }, { "signature" : { "accession" : "PS00687", "name" : "ALDEHYDE_DEHYDR_GLU", "description" : "Aldehyde dehydrogenases glutamic acid active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR029510", "name" : "Ald_DH_CS_GLU", "description" : "Aldehyde dehydrogenase, glutamic acid active site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 274, "end" : 281, "level" : "STRONG", "cigarAlignment" : "8M", "alignment" : "FELGGNAP", "location-fragments" : [ { "start" : 274, "end" : 281, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00687" }, { "signature" : { "accession" : "TIGR01780", "name" : "TIGR01780", "description" : "SSADH: succinate-semialdehyde dehydrogenase", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR010102", "name" : "Succ_semiAld_DH", "description" : "Succinate semialdehyde dehydrogenase", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "gamma-aminobutyric acid catabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0009450" }, { "name" : "succinate-semialdehyde dehydrogenase [NAD(P)+] activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0009013" } ], "pathwayXRefs" : [ { "name" : "Degradation of GABA", "databaseName" : "Reactome", "id" : "R-HSA-916853" } ] } }, "locations" : [ { "start" : 47, "end" : 496, "hmmStart" : 1, "hmmEnd" : 448, "hmmLength" : 448, "hmmBounds" : "COMPLETE", "evalue" : 5.0E-200, "score" : 663.0, "envelopeStart" : 47, "envelopeEnd" : 496, "postProcessed" : false, "location-fragments" : [ { "start" : 47, "end" : 496, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-200, "score" : 663.2, "model-ac" : "TIGR01780" }, { "signature" : { "accession" : "PTHR43353", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 23, "end" : 503, "hmmStart" : 5, "hmmEnd" : 482, "hmmLength" : 483, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 18, "envelopeEnd" : 504, "location-fragments" : [ { "start" : 23, "end" : 503, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-224, "familyName" : "SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL", "score" : 749.2, "model-ac" : "PTHR43353" } ], "xref" : [ { "name" : "XP_018909920.1 PREDICTED: succinate-semialdehyde dehydrogenase, mitochondrial [Bemisia tabaci]", "id" : "XP_018909920.1" } ] },{ "sequence" : "MVEPATKLNLDPKQQQRFIAFFKSLPQKPATTIRFFNRTDFYTLHGSDAVFAAKEVYKTTSFLKMIGSENDKLESIILNKNNFESFLRDLLLVKSYRVEVYCNKPTAKGSASWVLEFKGSPGNLSQFEDLLFDSVDQVEWNCVAAIKIGTKNKDKVVGVAMVDAVDHKFNVCEFVDDEYFTNLGAFITQHGPKECLVPDGCCENAKKVVSRGGILVSSRKNAEFSDDGLVQELNKLLLFQDGQLEKAAALPEMNLKIAAGALHAIIKYLELLSNQENYAQYSISTFELSKFVHLDASAVQALNITPQSQSTIFNKHHSIIGLLDKCRTSHGHRLLAQWIKQPLCDINAIQERHDIVEALATDITLRASLHDDHLRRIPDLQALSKKVHRKKANLQDCYRIYQAVSKLPDLLNSLETSYQDNPQPTLSSCFITPLKEQITELDKYQEMVQSTIDLDSVDKGEYLIKSEFDQDLQDYREKMEKLEEQMKKHLTSVASDLDYQAHKQIKLESNSMHGFFFRVTLKDAKAITRNKSYEVLDTNKGGARFRTKKLDSLNEEYLQIRENYTKHQESIVNEVVSIAAGYTNTLQFLSFTLAQLDVLCSFAMVAESAPKPFVRPKMHPKGTGILSLKQCRHPCLELEDGISYVPNDVHFEQGKSTFIIITGPNMGGKSTYIRSIGVTALLAHIGCFVPCDSAEISILDAILARMGAHDSQLKGMSTFMVEMVETSSIIRKATADSLVIIDELGRGTSTYEGCGIAWAIVEHLAKEIKCPSLFATHFHELTRLADEIETIHNFHVTALTLEDKLLLLYQVKPGVCNRSFGIHIAKMAKFPDRVVEESEQELQELEDFQAAAASLPENDRKRHIQEGEQLMEDFYSKVMRLKTSESSEEDIEKKFEELKQDLLSKKNPYIEALIK", "md5" : "631ed7381d886e7e22c37db87bd26c03", "matches" : [ { "signature" : { "accession" : "PF05190", "name" : "MutS_IV", "description" : "MutS family domain IV", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR007861", "name" : "DNA_mismatch_repair_MutS_clamp", "description" : "DNA mismatch repair protein MutS, clamp", "type" : "DOMAIN", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 467, "end" : 562, "hmmStart" : 1, "hmmEnd" : 91, "hmmLength" : 92, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.8E-18, "score" : 66.0, "envelopeStart" : 467, "envelopeEnd" : 563, "postProcessed" : true, "location-fragments" : [ { "start" : 467, "end" : 562, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-18, "score" : 66.0, "model-ac" : "PF05190" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 465, "end" : 492, "location-fragments" : [ { "start" : 465, "end" : 492, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF05188", "name" : "MutS_II", "description" : "MutS domain II", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR007860", "name" : "DNA_mmatch_repair_MutS_con_dom", "description" : "DNA mismatch repair protein MutS, connector domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 143, "end" : 279, "hmmStart" : 3, "hmmEnd" : 134, "hmmLength" : 137, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-16, "score" : 60.8, "envelopeStart" : 141, "envelopeEnd" : 282, "postProcessed" : true, "location-fragments" : [ { "start" : 143, "end" : 279, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-17, "score" : 63.5, "model-ac" : "PF05188" }, { "signature" : { "accession" : "PS00486", "name" : "DNA_MISMATCH_REPAIR_2", "description" : "DNA mismatch repair proteins mutS family signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000432", "name" : "DNA_mismatch_repair_MutS_C", "description" : "DNA mismatch repair protein MutS, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 737, "end" : 753, "level" : "STRONG", "cigarAlignment" : "2M1I1M1I7M4I1M", "alignment" : "SLvIiDELGRGTstyeG", "location-fragments" : [ { "start" : 737, "end" : 753, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00486" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 613, "end" : 847, "hmmLength" : 234, "location-fragments" : [ { "start" : 613, "end" : 847, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.59E-55, "model-ac" : "0036748" }, { "signature" : { "accession" : "G3DSA:3.40.1170.10", "name" : "DNA repair protein MutS", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR016151", "name" : "DNA_mismatch_repair_MutS_N", "description" : "DNA mismatch repair protein MutS, N-terminal", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" } ], "pathwayXRefs" : [ { "name" : "Defective Mismatch Repair Associated With MSH2", "databaseName" : "Reactome", "id" : "R-HSA-5632928" } ] } }, "locations" : [ { "start" : 1, "end" : 120, "hmmStart" : 4, "hmmEnd" : 124, "hmmLength" : 124, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-43, "score" : 148.6, "envelopeStart" : 1, "envelopeEnd" : 120, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 120, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-43, "score" : 149.5, "model-ac" : "2o8bA01" }, { "signature" : { "accession" : "SSF53150", "name" : "DNA repair protein MutS, domain II", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036678", "name" : "MutS_con_dom_sf", "description" : "MutS, connector domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 139, "end" : 276, "hmmLength" : 153, "location-fragments" : [ { "start" : 139, "end" : 276, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.75E-7, "model-ac" : "0046450" }, { "signature" : { "accession" : "SM00534", "name" : "mutATP5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000432", "name" : "DNA_mismatch_repair_MutS_C", "description" : "DNA mismatch repair protein MutS, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 656, "end" : 843, "hmmStart" : 1, "hmmEnd" : 199, "hmmLength" : 199, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-110, "score" : 381.7, "location-fragments" : [ { "start" : 656, "end" : 843, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-110, "score" : 381.7, "model-ac" : "SM00534" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 550, "end" : 570, "location-fragments" : [ { "start" : 550, "end" : 570, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF05192", "name" : "MutS_III", "description" : "MutS domain III", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR007696", "name" : "DNA_mismatch_repair_MutS_core", "description" : "DNA mismatch repair protein MutS, core", "type" : "DOMAIN", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 298, "end" : 603, "hmmStart" : 2, "hmmEnd" : 191, "hmmLength" : 191, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 9.2E-36, "score" : 123.9, "envelopeStart" : 297, "envelopeEnd" : 603, "postProcessed" : true, "location-fragments" : [ { "start" : 298, "end" : 466, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 563, "end" : 603, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 9.2E-36, "score" : 123.9, "model-ac" : "PF05192" }, { "signature" : { "accession" : "PIRSF005813", "name" : "MSH2", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR011184", "name" : "DNA_mismatch_repair_Msh2", "description" : "DNA mismatch repair Msh2-type", "type" : "FAMILY", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 914, "hmmStart" : 7, "hmmEnd" : 906, "hmmLength" : 923, "hmmBounds" : "INCOMPLETE", "evalue" : 0.0, "score" : 1093.2, "envelopeStart" : 1, "envelopeEnd" : 914, "postProcessed" : false, "location-fragments" : [ { "start" : 1, "end" : 914, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "score" : 1093.5, "model-ac" : "PIRSF005813" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 614, "end" : 915, "hmmStart" : 1, "hmmEnd" : 308, "hmmLength" : 315, "hmmBounds" : "COMPLETE", "evalue" : 4.9E-116, "score" : 389.1, "envelopeStart" : 614, "envelopeEnd" : 915, "postProcessed" : true, "location-fragments" : [ { "start" : 614, "end" : 915, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-116, "score" : 389.1, "model-ac" : "3thxA05" }, { "signature" : { "accession" : "G3DSA:1.10.1420.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 465, "end" : 547, "hmmStart" : 4, "hmmEnd" : 293, "hmmLength" : 83, "hmmBounds" : "INCOMPLETE", "evalue" : 1.1E-97, "score" : 329.3, "envelopeStart" : 309, "envelopeEnd" : 605, "postProcessed" : true, "location-fragments" : [ { "start" : 465, "end" : 547, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-97, "score" : 329.3, "model-ac" : "2o8bA04" }, { "signature" : { "accession" : "G3DSA:3.30.420.110", "name" : "DNA repair protein MutS", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036678", "name" : "MutS_con_dom_sf", "description" : "MutS, connector domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 121, "end" : 289, "hmmStart" : 1, "hmmEnd" : 172, "hmmLength" : 173, "hmmBounds" : "COMPLETE", "evalue" : 5.8E-49, "score" : 168.2, "envelopeStart" : 121, "envelopeEnd" : 289, "postProcessed" : true, "location-fragments" : [ { "start" : 121, "end" : 289, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-49, "score" : 168.2, "model-ac" : "3thxA02" }, { "signature" : { "accession" : "PF01624", "name" : "MutS_I", "description" : "MutS domain I", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR007695", "name" : "DNA_mismatch_repair_MutS-lik_N", "description" : "DNA mismatch repair protein MutS-like, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" } ], "pathwayXRefs" : [ { "name" : "Defective Mismatch Repair Associated With MSH2", "databaseName" : "Reactome", "id" : "R-HSA-5632928" } ] } }, "locations" : [ { "start" : 17, "end" : 127, "hmmStart" : 2, "hmmEnd" : 112, "hmmLength" : 113, "hmmBounds" : "INCOMPLETE", "evalue" : 4.6E-16, "score" : 59.1, "envelopeStart" : 16, "envelopeEnd" : 128, "postProcessed" : true, "location-fragments" : [ { "start" : 17, "end" : 127, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-16, "score" : 60.9, "model-ac" : "PF01624" }, { "signature" : { "accession" : "PTHR11361:SF35", "name" : "DNA MISMATCH REPAIR PROTEIN MSH2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR032642", "name" : "Msh2", "description" : "DNA mismatch repair protein Msh2", "type" : "FAMILY", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" }, { "name" : "mismatch repair complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0032300" } ], "pathwayXRefs" : [ { "name" : "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)", "databaseName" : "Reactome", "id" : "R-HSA-5358565" }, { "name" : "Defective Mismatch Repair Associated With MSH2", "databaseName" : "Reactome", "id" : "R-HSA-5632928" }, { "name" : "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)", "databaseName" : "Reactome", "id" : "R-HSA-5358606" }, { "name" : "Defective Mismatch Repair Associated With MSH6", "databaseName" : "Reactome", "id" : "R-HSA-5632968" }, { "name" : "TP53 Regulates Transcription of DNA Repair Genes", "databaseName" : "Reactome", "id" : "R-HSA-6796648" }, { "name" : "Defective Mismatch Repair Associated With MSH3", "databaseName" : "Reactome", "id" : "R-HSA-5632927" } ] } }, "locations" : [ { "start" : 18, "end" : 908, "hmmStart" : 1, "hmmEnd" : 825, "hmmLength" : 830, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 18, "envelopeEnd" : 913, "location-fragments" : [ { "start" : 18, "end" : 908, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.2E-281, "familyName" : "DNA MISMATCH REPAIR PROTEIN MSH2", "score" : 937.0, "model-ac" : "PTHR11361:SF35" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 881, "end" : 901, "location-fragments" : [ { "start" : 881, "end" : 901, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "G3DSA:1.10.1420.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 315, "end" : 605, "hmmStart" : 4, "hmmEnd" : 293, "hmmLength" : 293, "hmmBounds" : "INCOMPLETE", "evalue" : 1.1E-97, "score" : 329.3, "envelopeStart" : 309, "envelopeEnd" : 605, "postProcessed" : true, "location-fragments" : [ { "start" : 315, "end" : 464, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 548, "end" : 605, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.1E-97, "score" : 329.3, "model-ac" : "2o8bA03" }, { "signature" : { "accession" : "SM00533", "name" : "DNAend", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR007696", "name" : "DNA_mismatch_repair_MutS_core", "description" : "DNA mismatch repair protein MutS, core", "type" : "DOMAIN", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 314, "end" : 639, "hmmStart" : 1, "hmmEnd" : 335, "hmmLength" : 335, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-86, "score" : 304.0, "location-fragments" : [ { "start" : 314, "end" : 639, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-86, "score" : 304.0, "model-ac" : "SM00533" }, { "signature" : { "accession" : "PTHR11361", "name" : "DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 908, "hmmStart" : 1, "hmmEnd" : 825, "hmmLength" : 830, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 18, "envelopeEnd" : 913, "location-fragments" : [ { "start" : 18, "end" : 908, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.2E-281, "familyName" : "DNA MISMATCH REPAIR PROTEIN MSH2", "score" : 937.0, "model-ac" : "PTHR11361" }, { "signature" : { "accession" : "PF00488", "name" : "MutS_V", "description" : "MutS domain V", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000432", "name" : "DNA_mismatch_repair_MutS_C", "description" : "DNA mismatch repair protein MutS, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "mismatch repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006298" }, { "name" : "mismatched DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030983" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 659, "end" : 846, "hmmStart" : 1, "hmmEnd" : 188, "hmmLength" : 188, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-81, "score" : 273.3, "envelopeStart" : 659, "envelopeEnd" : 846, "postProcessed" : true, "location-fragments" : [ { "start" : 659, "end" : 846, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.2E-82, "score" : 274.2, "model-ac" : "PF00488" }, { "signature" : { "accession" : "SSF48334", "name" : "DNA repair protein MutS, domain III", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036187", "name" : "DNA_mismatch_repair_MutS_sf", "description" : "DNA mismatch repair protein MutS, core domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 295, "end" : 608, "hmmLength" : 297, "location-fragments" : [ { "start" : 295, "end" : 608, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.46E-68, "model-ac" : "0036747" } ], "xref" : [ { "name" : "XP_018910065.1 PREDICTED: DNA mismatch repair protein Msh2 [Bemisia tabaci]", "id" : "XP_018910065.1" } ] },{ "sequence" : "MFPLMEQCTNVLNGYLEDQLDSSAEIEVQQLMMQFAIDVIGTCAFGFNCNAISGSESEFRAVARKMSPGFLKFRLRHVLNSISPKIVPWLGWKGMNQEVEDFFMEVTREAIRHREENENKRTDFMQLLINLQHEERKALREDTELVFSDYIIAAQVFVFFVAGFETISTTLATCLYELALNPEVAKKIHDEIERVLEARGGKLDYDALKQMRYMECVIEETLRKYPPLGFLERTCTKAYELPNSHVLIKEGTRVAIPVYALHHDPQYFPEPEKFDPDRFNDENRSRIVPGTYLPFGDGPRICIGMRFALMEARAALTLIMRNYTVHATPRTQIPLTFDKKPLLLAHPEGGVFLRFQKREN", "md5" : "fc75b75cb407e034c88bce9f6ea3c818", "matches" : [ { "signature" : { "accession" : "SSF48264", "name" : "Cytochrome P450", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036396", "name" : "Cyt_P450_sf", "description" : "Cytochrome P450 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 358, "hmmLength" : 463, "location-fragments" : [ { "start" : 1, "end" : 358, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.31E-92, "model-ac" : "0054912" }, { "signature" : { "accession" : "PS00086", "name" : "CYTOCHROME_P450", "description" : "Cytochrome P450 cysteine heme-iron ligand signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017972", "name" : "Cyt_P450_CS", "description" : "Cytochrome P450, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 295, "end" : 304, "level" : "STRONG", "cigarAlignment" : "2M1I7M", "alignment" : "FGdGPRICIG", "location-fragments" : [ { "start" : 295, "end" : 304, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00086" }, { "signature" : { "accession" : "PTHR24292", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 356, "hmmStart" : 123, "hmmEnd" : 474, "hmmLength" : 474, "hmmBounds" : "COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 356, "location-fragments" : [ { "start" : 1, "end" : 356, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-118, "familyName" : "FAMILY NOT NAMED", "score" : 397.4, "model-ac" : "PTHR24292" }, { "signature" : { "accession" : "PF00067", "name" : "p450", "description" : "Cytochrome P450", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001128", "name" : "Cyt_P450", "description" : "Cytochrome P450", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 350, "hmmStart" : 114, "hmmEnd" : 459, "hmmLength" : 463, "hmmBounds" : "INCOMPLETE", "evalue" : 5.1E-86, "score" : 289.3, "envelopeStart" : 1, "envelopeEnd" : 354, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 350, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-86, "score" : 289.5, "model-ac" : "PF00067" }, { "signature" : { "accession" : "PR00385", "name" : "P450", "description" : "P450 superfamily signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001128", "name" : "Cyt_P450", "description" : "Cytochrome P450", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 162, "end" : 179, "pvalue" : 6.4E-7, "score" : 41.27, "motifNumber" : 1, "location-fragments" : [ { "start" : 162, "end" : 179, "dc-status" : "CONTINUOUS" } ] }, { "start" : 216, "end" : 227, "pvalue" : 1.0E-4, "score" : 42.78, "motifNumber" : 3, "location-fragments" : [ { "start" : 216, "end" : 227, "dc-status" : "CONTINUOUS" } ] }, { "start" : 293, "end" : 302, "pvalue" : 2.73E-5, "score" : 61.44, "motifNumber" : 4, "location-fragments" : [ { "start" : 293, "end" : 302, "dc-status" : "CONTINUOUS" } ] }, { "start" : 302, "end" : 313, "pvalue" : 4.81E-4, "score" : 43.68, "motifNumber" : 5, "location-fragments" : [ { "start" : 302, "end" : 313, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-12, "graphscan" : "I.III", "model-ac" : "PR00385" }, { "signature" : { "accession" : "G3DSA:1.10.630.10", "name" : "Cytochrome p450", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036396", "name" : "Cyt_P450_sf", "description" : "Cytochrome P450 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 360, "hmmStart" : 125, "hmmEnd" : 477, "hmmLength" : 487, "hmmBounds" : "COMPLETE", "evalue" : 3.3E-107, "score" : 361.0, "envelopeStart" : 1, "envelopeEnd" : 360, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 360, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-107, "score" : 361.1, "model-ac" : "4d6zA00" }, { "signature" : { "accession" : "PR00463", "name" : "EP450I", "description" : "E-class P450 group I signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002401", "name" : "Cyt_P450_E_grp-I", "description" : "Cytochrome P450, E-class, group I", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 302, "end" : 325, "pvalue" : 5.19E-5, "score" : 26.64, "motifNumber" : 9, "location-fragments" : [ { "start" : 302, "end" : 325, "dc-status" : "CONTINUOUS" } ] }, { "start" : 171, "end" : 197, "pvalue" : 7.48E-7, "score" : 31.56, "motifNumber" : 5, "location-fragments" : [ { "start" : 171, "end" : 197, "dc-status" : "CONTINUOUS" } ] }, { "start" : 292, "end" : 302, "pvalue" : 3.84E-5, "score" : 53.38, "motifNumber" : 8, "location-fragments" : [ { "start" : 292, "end" : 302, "dc-status" : "CONTINUOUS" } ] }, { "start" : 151, "end" : 168, "pvalue" : 1.78E-4, "score" : 33.7, "motifNumber" : 4, "location-fragments" : [ { "start" : 151, "end" : 168, "dc-status" : "CONTINUOUS" } ] }, { "start" : 257, "end" : 281, "pvalue" : 2.09E-9, "score" : 35.39, "motifNumber" : 7, "location-fragments" : [ { "start" : 257, "end" : 281, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-22, "graphscan" : "...II.IIi", "model-ac" : "PR00463" } ], "xref" : [ { "name" : "XP_018910194.1 PREDICTED: cytochrome P450 3A19-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910194.1" } ] },{ "sequence" : "MKNTLFVLVFGFVCQLESGDGSESEVRQQNEIWQTKKLKPVHYGSLDAKAVNLLFEDFISQYNKQYLSPAEKEKRLKIFSENLKDFDRLNDAERGTARYGVNQFADMTVEEFKQTMLTLRKDELPKTESRSSDELGLDGLKIPKNLDWREKGAVTPIKEQRYCGSCWAFSAVANLEGLYYIKHKKLETFSEQQLVDCDPLSKGCNGGWMSYAIEYVKQAGGLQSTPTYPYKARQGNCSADASLAVVKVKENIELPAKNEKKMAQAVFKHGPISVALDARAMRAYLDGIAHPPETMCGKDEDTLNHGVTLVGYGVQVVDTGNKKKTRLPYWIAKNSWGPRWGAKGYYYIYRGDGSCGISLYPSTAVIY", "md5" : "45f9e021723e3ee5a1b59216655caf7e", "matches" : [ { "signature" : { "accession" : "PF08246", "name" : "Inhibitor_I29", "description" : "Cathepsin propeptide inhibitor domain (I29)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013201", "name" : "Prot_inhib_I29", "description" : "Cathepsin propeptide inhibitor domain (I29)", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 55, "end" : 112, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 3.3E-12, "score" : 46.6, "envelopeStart" : 55, "envelopeEnd" : 112, "postProcessed" : true, "location-fragments" : [ { "start" : 55, "end" : 112, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-12, "score" : 47.8, "model-ac" : "PF08246" }, { "signature" : { "accession" : "PF00112", "name" : "Peptidase_C1", "description" : "Papain family cysteine protease", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 142, "end" : 362, "hmmStart" : 1, "hmmEnd" : 215, "hmmLength" : 218, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 8.3E-68, "score" : 228.7, "envelopeStart" : 142, "envelopeEnd" : 365, "postProcessed" : true, "location-fragments" : [ { "start" : 142, "end" : 362, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.4E-68, "score" : 229.1, "model-ac" : "PF00112" }, { "signature" : { "accession" : "PS00640", "name" : "THIOL_PROTEASE_ASN", "description" : "Eukaryotic thiol (cysteine) proteases asparagine active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR025661", "name" : "Pept_asp_AS", "description" : "Cysteine peptidase, asparagine active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 329, "end" : 348, "level" : "STRONG", "cigarAlignment" : "3M1I4M3I2M2I3M1I1M", "alignment" : "YWIaKNSWgprWGakGYYyI", "location-fragments" : [ { "start" : 329, "end" : 348, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00640" }, { "signature" : { "accession" : "PS00139", "name" : "THIOL_PROTEASE_CYS", "description" : "Eukaryotic thiol (cysteine) proteases cysteine active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000169", "name" : "Pept_cys_AS", "description" : "Cysteine peptidase, cysteine active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 160, "end" : 171, "level" : "STRONG", "cigarAlignment" : "2M1I6M1I2M", "alignment" : "QRyCGSCWAfSA", "location-fragments" : [ { "start" : 160, "end" : 171, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00139" }, { "signature" : { "accession" : "PTHR12411:SF316", "name" : "CATHEPSIN F", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 54, "end" : 358, "hmmStart" : 16, "hmmEnd" : 293, "hmmLength" : 297, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 363, "location-fragments" : [ { "start" : 54, "end" : 358, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.5E-90, "familyName" : "CATHEPSIN F", "score" : 304.6, "model-ac" : "PTHR12411:SF316" }, { "signature" : { "accession" : "PTHR12411", "name" : "CYSTEINE PROTEASE FAMILY C1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 54, "end" : 358, "hmmStart" : 16, "hmmEnd" : 293, "hmmLength" : 297, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 363, "location-fragments" : [ { "start" : 54, "end" : 358, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.5E-90, "familyName" : "CATHEPSIN F", "score" : 304.6, "model-ac" : "PTHR12411" }, { "signature" : { "accession" : "PS00639", "name" : "THIOL_PROTEASE_HIS", "description" : "Eukaryotic thiol (cysteine) proteases histidine active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR025660", "name" : "Pept_his_AS", "description" : "Cysteine peptidase, histidine active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 303, "end" : 313, "level" : "STRONG", "cigarAlignment" : "11M", "alignment" : "LNHGVTLVGYG", "location-fragments" : [ { "start" : 303, "end" : 313, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00639" }, { "signature" : { "accession" : "SM00645", "name" : "pept_c1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 142, "end" : 365, "hmmStart" : 1, "hmmEnd" : 340, "hmmLength" : 340, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-86, "score" : 303.1, "location-fragments" : [ { "start" : 142, "end" : 365, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-86, "score" : 303.1, "model-ac" : "SM00645" }, { "signature" : { "accession" : "SM00848", "name" : "Inhibitor_I29_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013201", "name" : "Prot_inhib_I29", "description" : "Cathepsin propeptide inhibitor domain (I29)", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 55, "end" : 112, "hmmStart" : 1, "hmmEnd" : 67, "hmmLength" : 67, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-20, "score" : 84.3, "location-fragments" : [ { "start" : 55, "end" : 112, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-20, "score" : 84.3, "model-ac" : "SM00848" }, { "signature" : { "accession" : "SSF54001", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038765", "name" : "Papain-like_cys_pep_sf", "description" : "Papain-like cysteine peptidase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 52, "end" : 365, "hmmLength" : 314, "location-fragments" : [ { "start" : 52, "end" : 365, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.26E-96, "model-ac" : "0053371" }, { "signature" : { "accession" : "cd02248", "name" : "Peptidase_C1A", "description" : "Peptidase_C1A", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR039417", "name" : "Peptidase_C1A_papain-like", "description" : "Papain-like cysteine endopeptidase", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "MHC class II antigen presentation", "databaseName" : "Reactome", "id" : "R-HSA-2132295" } ] } }, "locations" : [ { "start" : 143, "end" : 364, "sites" : [ { "description" : "active site", "numLocations" : 4, "siteLocations" : [ { "start" : 160, "end" : 160, "residue" : "Q" }, { "start" : 166, "end" : 166, "residue" : "C" }, { "start" : 305, "end" : 305, "residue" : "H" }, { "start" : 334, "end" : 334, "residue" : "N" } ] }, { "description" : "S2 subsite", "numLocations" : 6, "siteLocations" : [ { "start" : 275, "end" : 275, "residue" : "A" }, { "start" : 303, "end" : 303, "residue" : "L" }, { "start" : 306, "end" : 306, "residue" : "G" }, { "start" : 360, "end" : 360, "residue" : "Y" }, { "start" : 209, "end" : 209, "residue" : "M" }, { "start" : 208, "end" : 208, "residue" : "W" } ] } ], "evalue" : 6.64037E-94, "score" : 277.198, "location-fragments" : [ { "start" : 143, "end" : 364, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd02248" }, { "signature" : { "accession" : "PR00705", "name" : "PAPAIN", "description" : "Papain cysteine protease (C1) family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000668", "name" : "Peptidase_C1A_C", "description" : "Peptidase C1A, papain C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 329, "end" : 335, "pvalue" : 0.00336, "score" : 71.6, "motifNumber" : 3, "location-fragments" : [ { "start" : 329, "end" : 335, "dc-status" : "CONTINUOUS" } ] }, { "start" : 160, "end" : 175, "pvalue" : 1.57E-7, "score" : 58.64, "motifNumber" : 1, "location-fragments" : [ { "start" : 160, "end" : 175, "dc-status" : "CONTINUOUS" } ] }, { "start" : 305, "end" : 315, "pvalue" : 5.7E-6, "score" : 56.62, "motifNumber" : 2, "location-fragments" : [ { "start" : 305, "end" : 315, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.5E-9, "graphscan" : "III", "model-ac" : "PR00705" }, { "signature" : { "accession" : "G3DSA:3.90.70.10", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 367, "hmmStart" : 32, "hmmEnd" : 342, "hmmLength" : 345, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-97, "score" : 328.2, "envelopeStart" : 24, "envelopeEnd" : 367, "postProcessed" : true, "location-fragments" : [ { "start" : 24, "end" : 367, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-97, "score" : 328.4, "model-ac" : "5ef4A00" } ], "xref" : [ { "name" : "XP_018909850.1 PREDICTED: LOW QUALITY PROTEIN: putative cysteine proteinase CG12163 [Bemisia tabaci]", "id" : "XP_018909850.1" } ] },{ "sequence" : "MVVSKPMHCIQDVCQKLLISYFENLHTHPYRTKAFTRLTFGWSGPHLLFSWLESAIPRKQNFSLLKRFAFERLVYTPFFQFLVLFTLSIYEGKSYQVSLKNAQTLYCKVLQANLKYLSLLQFMNLAYVPPMLRVLFSNMIGFVWILFLSHQRKQSQEKTPRIRN", "md5" : "7b864a49d05d19084c80af73bee1dca5", "matches" : [ { "signature" : { "accession" : "PF04117", "name" : "Mpv17_PMP22", "description" : "Mpv17 / PMP22 family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR007248", "name" : "Mpv17_PMP22", "description" : "Mpv17/PMP22", "type" : "FAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 89, "end" : 149, "hmmStart" : 2, "hmmEnd" : 62, "hmmLength" : 62, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.5E-13, "score" : 50.7, "envelopeStart" : 88, "envelopeEnd" : 149, "postProcessed" : true, "location-fragments" : [ { "start" : 89, "end" : 149, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-14, "score" : 52.0, "model-ac" : "PF04117" }, { "signature" : { "accession" : "PTHR11266:SF80", "name" : "PEROXISOMAL MEMBRANE PROTEIN 2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 31, "end" : 154, "hmmStart" : 277, "hmmEnd" : 401, "hmmLength" : 471, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 13, "envelopeEnd" : 163, "location-fragments" : [ { "start" : 31, "end" : 154, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-23, "familyName" : "PEROXISOMAL MEMBRANE PROTEIN 2", "score" : 85.2, "model-ac" : "PTHR11266:SF80" }, { "signature" : { "accession" : "PTHR11266", "name" : "PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR007248", "name" : "Mpv17_PMP22", "description" : "Mpv17/PMP22", "type" : "FAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 31, "end" : 154, "hmmStart" : 277, "hmmEnd" : 401, "hmmLength" : 471, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 13, "envelopeEnd" : 163, "location-fragments" : [ { "start" : 31, "end" : 154, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-23, "familyName" : "PEROXISOMAL MEMBRANE PROTEIN 2", "score" : 85.2, "model-ac" : "PTHR11266" } ], "xref" : [ { "name" : "XP_018909996.1 PREDICTED: peroxisomal membrane protein 2 isoform X4 [Bemisia tabaci]", "id" : "XP_018909996.1" }, { "name" : "XP_018909997.1 PREDICTED: peroxisomal membrane protein 2 isoform X4 [Bemisia tabaci]", "id" : "XP_018909997.1" } ] },{ "sequence" : "MEYNFTGKTVLVTGAGSGIGKGLCLKLSKCGAKVIAVSVIQKELDDLVEEVPSVQPICVDLAKWDETKTALEKVGPVDGLVNNAGIALLSPFFDITEDEFDRSFDVNVKAILCVSQVIGKGMVERKKGSIVNISSIASRFGYENHTVYCGTKTAVDGMTRAMALELGKHNVRVNCVCPVVVLTPLGRQWWAEPSRANPMLNRIPLGRFAEIEDIVNPVMFLLTDNASMINGARLPVDGGHTNAPFHCSE", "md5" : "e0f932052702cf64abadffc7cc54fa0a", "matches" : [ { "signature" : { "accession" : "PR00080", "name" : "SDRFAMILY", "description" : "Short-chain dehydrogenase/reductase (SDR) superfamily signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002347", "name" : "SDR_fam", "description" : "Short-chain dehydrogenase/reductase SDR", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 75, "end" : 86, "pvalue" : 4.8E-7, "score" : 60.75, "motifNumber" : 1, "location-fragments" : [ { "start" : 75, "end" : 86, "dc-status" : "CONTINUOUS" } ] }, { "start" : 128, "end" : 136, "pvalue" : 2.03E-5, "score" : 58.13, "motifNumber" : 2, "location-fragments" : [ { "start" : 128, "end" : 136, "dc-status" : "CONTINUOUS" } ] }, { "start" : 148, "end" : 167, "pvalue" : 2.82E-7, "score" : 34.61, "motifNumber" : 3, "location-fragments" : [ { "start" : 148, "end" : 167, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-12, "graphscan" : "III", "model-ac" : "PR00080" }, { "signature" : { "accession" : "SSF51735", "name" : "NAD(P)-binding Rossmann-fold domains", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036291", "name" : "NAD(P)-bd_dom_sf", "description" : "NAD(P)-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 241, "hmmLength" : 329, "location-fragments" : [ { "start" : 7, "end" : 241, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-75, "model-ac" : "0049902" }, { "signature" : { "accession" : "PS00061", "name" : "ADH_SHORT", "description" : "Short-chain dehydrogenases/reductases family signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR020904", "name" : "Sc_DH/Rdtase_CS", "description" : "Short-chain dehydrogenase/reductase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 135, "end" : 163, "level" : "STRONG", "cigarAlignment" : "1M9I1M2I8M1I3M1I3M", "alignment" : "SiasrfgyenHtvYCGTKTAVdGMTrAMA", "location-fragments" : [ { "start" : 135, "end" : 163, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00061" }, { "signature" : { "accession" : "PR00081", "name" : "GDHRDH", "description" : "Glucose/ribitol dehydrogenase family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002347", "name" : "SDR_fam", "description" : "Short-chain dehydrogenase/reductase SDR", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 204, "end" : 224, "pvalue" : 8.1E-9, "score" : 32.12, "motifNumber" : 6, "location-fragments" : [ { "start" : 204, "end" : 224, "dc-status" : "CONTINUOUS" } ] }, { "start" : 75, "end" : 86, "pvalue" : 5.92E-7, "score" : 61.17, "motifNumber" : 2, "location-fragments" : [ { "start" : 75, "end" : 86, "dc-status" : "CONTINUOUS" } ] }, { "start" : 148, "end" : 167, "pvalue" : 1.48E-8, "score" : 38.35, "motifNumber" : 4, "location-fragments" : [ { "start" : 148, "end" : 167, "dc-status" : "CONTINUOUS" } ] }, { "start" : 169, "end" : 186, "pvalue" : 1.21E-6, "score" : 37.14, "motifNumber" : 5, "location-fragments" : [ { "start" : 169, "end" : 186, "dc-status" : "CONTINUOUS" } ] }, { "start" : 9, "end" : 26, "pvalue" : 1.26E-8, "score" : 41.34, "motifNumber" : 1, "location-fragments" : [ { "start" : 9, "end" : 26, "dc-status" : "CONTINUOUS" } ] }, { "start" : 122, "end" : 138, "pvalue" : 1.53E-8, "score" : 38.16, "motifNumber" : 3, "location-fragments" : [ { "start" : 122, "end" : 138, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-38, "graphscan" : "IIIIII", "model-ac" : "PR00081" }, { "signature" : { "accession" : "PF13561", "name" : "adh_short_C2", "description" : "Enoyl-(Acyl carrier protein) reductase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 241, "hmmStart" : 1, "hmmEnd" : 234, "hmmLength" : 234, "hmmBounds" : "COMPLETE", "evalue" : 4.9E-55, "score" : 186.6, "envelopeStart" : 14, "envelopeEnd" : 241, "postProcessed" : true, "location-fragments" : [ { "start" : 14, "end" : 241, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-55, "score" : 186.9, "model-ac" : "PF13561" }, { "signature" : { "accession" : "G3DSA:3.40.50.720", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 243, "hmmStart" : 3, "hmmEnd" : 241, "hmmLength" : 244, "hmmBounds" : "COMPLETE", "evalue" : 6.1E-78, "score" : 263.5, "envelopeStart" : 1, "envelopeEnd" : 243, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 243, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-78, "score" : 263.7, "model-ac" : "3d3wA00" }, { "signature" : { "accession" : "PTHR44252", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 242, "hmmStart" : 1, "hmmEnd" : 243, "hmmLength" : 244, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 243, "location-fragments" : [ { "start" : 1, "end" : 242, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-107, "familyName" : "FAMILY NOT NAMED", "score" : 360.6, "model-ac" : "PTHR44252" } ], "xref" : [ { "name" : "XP_018910307.1 PREDICTED: L-xylulose reductase-like [Bemisia tabaci]", "id" : "XP_018910307.1" } ] },{ "sequence" : "MTRRQEEQGLKMLLMAFAVAACCTVEARKTSRKPHIIIMLADDMGWNDVGFHGSNQIPTPNIDALAYNGLILNSHYTPALCTPSRAALMTGKYPIHLGMQHLVILEAEPWGLPLEEKMLPQYLKESGYATHAIGKWHLGFFRKEYTPTHRGFDSHFGYWQGFQDYYDHSVKATFAKYHGYDMRRNMSLDWSAQGKYSTDLFTDEAVRIINTHEREDPLFLYMAHLAPHTANTYEPFQAPDEEVVRFAHIEDPERRTYAAMVSKLDQSVGEVVSALRSRDMLDNSIIIFMSDNGAPTYGLHSNRGSNYPLRGIKETPYEGGVRGVAAVWSPLIKKRSRVANQLMHIADWLPTLHSAAGLESSLPKDLDGVDMWKALSEDLPSPRTELLHNIDDIGEVYSALRSGPWKYVKGSVSKGRTDSWYGESGRSNNLTDDEVRSYDVTAVLHSKAGAALGGFVTKQQIKTKEMRLNAINSVAANANYDFPKFEDELRLLTARGVLALRAAAEVRCNESMAPRECDATKSACLFNIAADPCERTNLAAAEPDLVRILEERVAELRKTARAPLNKPSDPLADPHNWNDTWTNWHDALDQLNQVQVTPPKPDLKVVVLFAAVVAVLCVLGLILAVKFVAPYALVPSDQYSSPRKFRSFTFGLKRETEDFQKGSVVT", "md5" : "b02f86b1504c5bb6c4c6e19820f44017", "matches" : [ { "signature" : { "accession" : "PTHR10342:SF264", "name" : "MIP05773P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 447, "hmmStart" : 10, "hmmEnd" : 443, "hmmLength" : 575, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 6, "envelopeEnd" : 485, "location-fragments" : [ { "start" : 15, "end" : 447, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-220, "familyName" : "MIP05773P", "score" : 735.9, "model-ac" : "PTHR10342:SF264" }, { "signature" : { "accession" : "PF00884", "name" : "Sulfatase", "description" : "Sulfatase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000917", "name" : "Sulfatase_N", "description" : "Sulfatase, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "sulfuric ester hydrolase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008484" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 34, "end" : 357, "hmmStart" : 1, "hmmEnd" : 308, "hmmLength" : 309, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.0E-72, "score" : 244.2, "envelopeStart" : 34, "envelopeEnd" : 358, "postProcessed" : true, "location-fragments" : [ { "start" : 34, "end" : 357, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-72, "score" : 244.5, "model-ac" : "PF00884" }, { "signature" : { "accession" : "G3DSA:3.40.720.10", "name" : "Alkaline Phosphatase", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR017850", "name" : "Alkaline_phosphatase_core_sf", "description" : "Alkaline-phosphatase-like, core domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 34, "end" : 383, "hmmStart" : 1, "hmmEnd" : 395, "hmmLength" : 371, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.6E-150, "score" : 502.3, "envelopeStart" : 34, "envelopeEnd" : 444, "postProcessed" : true, "location-fragments" : [ { "start" : 34, "end" : 383, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-161, "score" : 537.7, "model-ac" : "1fsuA01" }, { "signature" : { "accession" : "PTHR10342", "name" : "ARYLSULFATASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 447, "hmmStart" : 10, "hmmEnd" : 443, "hmmLength" : 575, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 6, "envelopeEnd" : 485, "location-fragments" : [ { "start" : 15, "end" : 447, "dc-status" : "CONTINUOUS" } ] }, { "start" : 512, "end" : 597, "hmmStart" : 472, "hmmEnd" : 557, "hmmLength" : 575, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 484, "envelopeEnd" : 613, "location-fragments" : [ { "start" : 512, "end" : 597, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-220, "familyName" : "MIP05773P", "score" : 735.9, "model-ac" : "PTHR10342" }, { "signature" : { "accession" : "PS00149", "name" : "SULFATASE_2", "description" : "Sulfatases signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR024607", "name" : "Sulfatase_CS", "description" : "Sulfatase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 127, "end" : 137, "level" : "STRONG", "cigarAlignment" : "2M1I1M2I5M", "alignment" : "GYaThaIGKWH", "location-fragments" : [ { "start" : 127, "end" : 137, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00149" }, { "signature" : { "accession" : "PS00523", "name" : "SULFATASE_1", "description" : "Sulfatases signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR024607", "name" : "Sulfatase_CS", "description" : "Sulfatase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 79, "end" : 91, "level" : "STRONG", "cigarAlignment" : "7M2I4M", "alignment" : "ALCTPSRaaLMTG", "location-fragments" : [ { "start" : 79, "end" : 91, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00523" }, { "signature" : { "accession" : "SSF53649", "name" : "Alkaline phosphatase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR017850", "name" : "Alkaline_phosphatase_core_sf", "description" : "Alkaline-phosphatase-like, core domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 584, "hmmLength" : 492, "location-fragments" : [ { "start" : 32, "end" : 423, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 487, "end" : 584, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 7.12E-126, "model-ac" : "0037763" }, { "signature" : { "accession" : "G3DSA:3.30.1120.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 499, "end" : 564, "hmmStart" : 34, "hmmEnd" : 73, "hmmLength" : 86, "hmmBounds" : "COMPLETE", "evalue" : 9.9E-6, "score" : 27.2, "envelopeStart" : 499, "envelopeEnd" : 564, "postProcessed" : true, "location-fragments" : [ { "start" : 499, "end" : 564, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-8, "score" : 34.2, "model-ac" : "1hdhA02" }, { "signature" : { "accession" : "G3DSA:3.30.1120.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 384, "end" : 427, "hmmStart" : 1, "hmmEnd" : 395, "hmmLength" : 121, "hmmBounds" : "INCOMPLETE", "evalue" : 4.6E-150, "score" : 502.3, "envelopeStart" : 34, "envelopeEnd" : 444, "postProcessed" : true, "location-fragments" : [ { "start" : 384, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-161, "score" : 537.7, "model-ac" : "1fsuA02" }, { "signature" : { "accession" : "PTHR10342:SF264", "name" : "MIP05773P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 512, "end" : 597, "hmmStart" : 472, "hmmEnd" : 557, "hmmLength" : 575, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 484, "envelopeEnd" : 613, "location-fragments" : [ { "start" : 512, "end" : 597, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-220, "familyName" : "MIP05773P", "score" : 735.9, "model-ac" : "PTHR10342:SF264" }, { "signature" : { "accession" : "cd16029", "name" : "4-S", "description" : "4-S", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 34, "end" : 410, "sites" : [ { "description" : "Ca binding site", "numLocations" : 5, "siteLocations" : [ { "start" : 43, "end" : 43, "residue" : "D" }, { "start" : 291, "end" : 291, "residue" : "D" }, { "start" : 81, "end" : 81, "residue" : "C" }, { "start" : 42, "end" : 42, "residue" : "D" }, { "start" : 292, "end" : 292, "residue" : "N" } ] }, { "description" : "putative substrate binding site", "numLocations" : 7, "siteLocations" : [ { "start" : 228, "end" : 228, "residue" : "H" }, { "start" : 43, "end" : 43, "residue" : "D" }, { "start" : 137, "end" : 137, "residue" : "H" }, { "start" : 135, "end" : 135, "residue" : "K" }, { "start" : 81, "end" : 81, "residue" : "C" }, { "start" : 42, "end" : 42, "residue" : "D" }, { "start" : 292, "end" : 292, "residue" : "N" } ] }, { "description" : "putative active site", "numLocations" : 8, "siteLocations" : [ { "start" : 228, "end" : 228, "residue" : "H" }, { "start" : 43, "end" : 43, "residue" : "D" }, { "start" : 137, "end" : 137, "residue" : "H" }, { "start" : 291, "end" : 291, "residue" : "D" }, { "start" : 135, "end" : 135, "residue" : "K" }, { "start" : 81, "end" : 81, "residue" : "C" }, { "start" : 42, "end" : 42, "residue" : "D" }, { "start" : 292, "end" : 292, "residue" : "N" } ] } ], "evalue" : 0.0, "score" : 637.671, "location-fragments" : [ { "start" : 34, "end" : 410, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd16029" }, { "signature" : { "accession" : "PS51257", "name" : "PROKAR_LIPOPROTEIN", "description" : "Prokaryotic membrane lipoprotein lipid attachment site profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 22, "score" : 6.0, "alignment" : "MTRR-------------QEEQGLKMLLMAFAVAAC", "location-fragments" : [ { "start" : 1, "end" : 22, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51257" } ], "xref" : [ { "name" : "XP_018909945.1 PREDICTED: arylsulfatase B-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909945.1" } ] },{ "sequence" : "MEVAEFQDFAKAMIDYISKYMSTIRDRPVLPKLEPGYLRPLIPESAPEEPESWHNVMEDIERVIMPGVTHWHSPRFHAYFPTACSYPAIVADMLSDAIACIGFTWIASPACTELEVVMMDWLGKMLNLPDDFLASGKKGGGGVIQGTASEATLVALLGAKTRAIRRTKEQHPDWTDLEIASKLVAYCSKQAHSSVERAGLLGSVPFRLLPTDDMYRLQGSTLEEAIKKDKADGLVPFYVVATLGTTSCCSFDLLKEIGPVCKNEEVWLHVDAAYAGSAFICPEYQYLLEGVEYAESFNFNPHKWMLVNFDCSAMWLKNPDEVVNAFNVDPLYLKHDHQGAAPDYRHWQIPLGRRFRSLKLWFVLRLYGIKNLQTHIRHQIGLAHQFEAYVNEDEEFELFNEVLMGLVCFRVKGSNELNEQVLNRINKKGKIHMVPSKIKDVFFLRFAVCSRFTNAEDVKYSWSEVKATTQEIKKELAKQ", "md5" : "57cd104152945f51fbe0768d39c2a82f", "matches" : [ { "signature" : { "accession" : "SSF53383", "name" : "PLP-dependent transferases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR015424", "name" : "PyrdxlP-dep_Trfase", "description" : "Pyridoxal phosphate-dependent transferase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 473, "hmmLength" : 476, "location-fragments" : [ { "start" : 1, "end" : 473, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.05E-150, "model-ac" : "0047670" }, { "signature" : { "accession" : "PF00282", "name" : "Pyridoxal_deC", "description" : "Pyridoxal-dependent decarboxylase conserved domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002129", "name" : "PyrdxlP-dep_de-COase", "description" : "Pyridoxal phosphate-dependent decarboxylase", "type" : "FAMILY", "goXRefs" : [ { "name" : "carboxy-lyase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016831" }, { "name" : "pyridoxal phosphate binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030170" }, { "name" : "carboxylic acid metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0019752" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 35, "end" : 412, "hmmStart" : 1, "hmmEnd" : 375, "hmmLength" : 375, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-163, "score" : 543.3, "envelopeStart" : 35, "envelopeEnd" : 412, "postProcessed" : true, "location-fragments" : [ { "start" : 35, "end" : 412, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-163, "score" : 543.5, "model-ac" : "PF00282" }, { "signature" : { "accession" : "G3DSA:1.20.1340.10", "name" : "dopa decarboxylase", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 81, "hmmStart" : 1, "hmmEnd" : 81, "hmmLength" : 81, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-35, "score" : 122.8, "envelopeStart" : 1, "envelopeEnd" : 81, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 81, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.5E-36, "score" : 124.6, "model-ac" : "3k40A01" }, { "signature" : { "accession" : "PR00800", "name" : "YHDCRBOXLASE", "description" : "Aromatic-L-amino-acid decarboxylase signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR010977", "name" : "Aromatic_deC", "description" : "Aromatic-L-amino-acid decarboxylase", "type" : "FAMILY", "goXRefs" : [ { "name" : "carboxy-lyase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016831" }, { "name" : "cellular amino acid metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006520" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 393, "end" : 412, "pvalue" : 4.78E-10, "score" : 52.29, "motifNumber" : 9, "location-fragments" : [ { "start" : 393, "end" : 412, "dc-status" : "CONTINUOUS" } ] }, { "start" : 94, "end" : 112, "pvalue" : 9.03E-11, "score" : 66.77, "motifNumber" : 5, "location-fragments" : [ { "start" : 94, "end" : 112, "dc-status" : "CONTINUOUS" } ] }, { "start" : 113, "end" : 132, "pvalue" : 7.47E-11, "score" : 69.43, "motifNumber" : 6, "location-fragments" : [ { "start" : 113, "end" : 132, "dc-status" : "CONTINUOUS" } ] }, { "start" : 350, "end" : 365, "pvalue" : 2.92E-10, "score" : 82.32, "motifNumber" : 8, "location-fragments" : [ { "start" : 350, "end" : 365, "dc-status" : "CONTINUOUS" } ] }, { "start" : 6, "end" : 25, "pvalue" : 1.41E-7, "score" : 38.29, "motifNumber" : 1, "location-fragments" : [ { "start" : 6, "end" : 25, "dc-status" : "CONTINUOUS" } ] }, { "start" : 73, "end" : 92, "pvalue" : 5.68E-12, "score" : 58.71, "motifNumber" : 4, "location-fragments" : [ { "start" : 73, "end" : 92, "dc-status" : "CONTINUOUS" } ] }, { "start" : 47, "end" : 66, "pvalue" : 4.84E-11, "score" : 49.43, "motifNumber" : 3, "location-fragments" : [ { "start" : 47, "end" : 66, "dc-status" : "CONTINUOUS" } ] }, { "start" : 140, "end" : 160, "pvalue" : 6.44E-15, "score" : 69.12, "motifNumber" : 7, "location-fragments" : [ { "start" : 140, "end" : 160, "dc-status" : "CONTINUOUS" } ] }, { "start" : 29, "end" : 46, "pvalue" : 8.82E-11, "score" : 60.0, "motifNumber" : 2, "location-fragments" : [ { "start" : 29, "end" : 46, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-86, "graphscan" : "IIIIIIIII", "model-ac" : "PR00800" }, { "signature" : { "accession" : "PTHR11999:SF144", "name" : "MIP05841P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 477, "hmmStart" : 1, "hmmEnd" : 478, "hmmLength" : 559, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 479, "location-fragments" : [ { "start" : 1, "end" : 477, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-223, "familyName" : "MIP05841P", "score" : 745.4, "model-ac" : "PTHR11999:SF144" }, { "signature" : { "accession" : "cd06450", "name" : "DOPA_deC_like", "description" : "DOPA_deC_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 76, "end" : 467, "sites" : [ { "description" : "pyridoxal 5'-phosphate binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 303, "end" : 303, "residue" : "K" }, { "start" : 274, "end" : 274, "residue" : "Y" }, { "start" : 271, "end" : 271, "residue" : "D" }, { "start" : 148, "end" : 148, "residue" : "A" }, { "start" : 242, "end" : 242, "residue" : "T" }, { "start" : 149, "end" : 149, "residue" : "S" }, { "start" : 300, "end" : 300, "residue" : "N" }, { "start" : 152, "end" : 152, "residue" : "T" } ] }, { "description" : "catalytic residue", "numLocations" : 1, "siteLocations" : [ { "start" : 303, "end" : 303, "residue" : "K" } ] } ], "evalue" : 1.67945E-132, "score" : 385.018, "location-fragments" : [ { "start" : 76, "end" : 467, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd06450" }, { "signature" : { "accession" : "G3DSA:3.90.1150.10", "name" : "Aspartate Aminotransferase", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015422", "name" : "PyrdxlP-dep_Trfase_dom1", "description" : "Pyridoxal phosphate-dependent transferase domain 1", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 378, "end" : 476, "hmmStart" : 3, "hmmEnd" : 97, "hmmLength" : 99, "hmmBounds" : "COMPLETE", "evalue" : 3.4E-35, "score" : 121.9, "envelopeStart" : 378, "envelopeEnd" : 476, "postProcessed" : true, "location-fragments" : [ { "start" : 378, "end" : 476, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.7E-36, "score" : 123.6, "model-ac" : "3k40A03" }, { "signature" : { "accession" : "PTHR11999", "name" : "GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 477, "hmmStart" : 1, "hmmEnd" : 478, "hmmLength" : 559, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 479, "location-fragments" : [ { "start" : 1, "end" : 477, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-223, "familyName" : "MIP05841P", "score" : 745.4, "model-ac" : "PTHR11999" }, { "signature" : { "accession" : "PS00392", "name" : "DDC_GAD_HDC_YDC", "description" : "DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR021115", "name" : "Pyridoxal-P_BS", "description" : "Pyridoxal-phosphate binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "carboxy-lyase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016831" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 296, "end" : 317, "level" : "STRONG", "cigarAlignment" : "2M1I1M3I3M1I1M1I3M2I2M1I1M", "alignment" : "SFnFnphKWMlVnFDCsaMWlK", "location-fragments" : [ { "start" : 296, "end" : 317, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00392" }, { "signature" : { "accession" : "G3DSA:3.40.640.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015421", "name" : "PyrdxlP-dep_Trfase_major", "description" : "Pyridoxal phosphate-dependent transferase, major domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 82, "end" : 377, "hmmStart" : 3, "hmmEnd" : 295, "hmmLength" : 295, "hmmBounds" : "COMPLETE", "evalue" : 4.0E-118, "score" : 395.5, "envelopeStart" : 82, "envelopeEnd" : 377, "postProcessed" : true, "location-fragments" : [ { "start" : 82, "end" : 377, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-118, "score" : 395.8, "model-ac" : "3k40A02" } ], "xref" : [ { "name" : "XP_018910260.1 PREDICTED: aromatic-L-amino-acid decarboxylase isoform X2 [Bemisia tabaci]", "id" : "XP_018910260.1" }, { "name" : "XP_018910261.1 PREDICTED: aromatic-L-amino-acid decarboxylase isoform X2 [Bemisia tabaci]", "id" : "XP_018910261.1" } ] },{ "sequence" : "MALTCRVQYLNDIDPFTYSTINFPEPPRPPVHTFCCNLPLINQIASVHRLLHAPHRLDDAALQLYKDGDYSSYLDLDATISEQQEEFEGFQSNRKNSIVLRTQLSVRVHTIIEKLLNSEGSELRRALFCLKQIFQEDKDLVHEFVQNDGLSCLIKVGSDANQNYQNYILRALGQVMLYVDGMNGVIEHNETIQWLYCLVSSKFRLVVKTALKLLLVFVEYVESNCLLLIQAIHTVDKSRGSLPWSNIMKLLNEYDVTDTELLIYAMTLINKTLNRVPDLDMYYDQVDEIEKQGIQEIVQRYMSRPGTDLDFLHQLQSYEAVLNHEDGGDKTIPLKQLDDNVRTTRFSNASMISDIERRRSRRHSTGTVPLSLSVSPYNKANEDYHLKQAAEDGVGVTPALRRRLERGDRQKLLIPQEELCKSSTENYSSDDGGMKNGLKSELSNGDLKYYNGETESCLPRENTVKDLTQRLATLNSPNEESPTKLTPPPRVGEMKGIISKAIEGLAKSQSKSELKSPTNETPPMRIPEVKKSETELHWEELLASTTRALQLCDLDFTDLGSDDEKNILAPTSVANGIPPPPPPCVLPPPAPAAPLQSLTKTKKTVKLFWKEVCEDPIVMAKMNSSLIWDELTPVPVDTQKLEHLFESRTKDLITKKQHELNKNKEIIVLDPKRSNAINIGMTKLPPPRAIKTAILKMDATVMNREGIEKLLTMLPSEEERTKIQEAQTANPELPLGSAEQFLLTLASIIELPARLKLWAFKLDYENSEKEIAEPLMDLKQGMELLKANKTFRAILATLLSIGIFLNGNEVKGFQIEYLAKVPEVKDTVHKHSLLHHLCHMVMSKFPQSTDLYSEIGAVTRASKVDFDELALSIHRMEQECKASFDHLKVIVKHDGSNAMKGKMSDFLADCAERIIVLCKVHRRVINRYHKFCLWLGIPLHRVCLTKPNELCRIISEFALEYRTTRERVLQQLEKKANHRERNKTRGKMITEIGKVDTKEDRADAELRQLLGNESIDRPNSASPLHGSLPWRRQKKNSNGKGSPDQRKNGHLTDGDDELLETLVKTATKIPATRSAPRERKRIRNADRKSFRQRTLRNGLSEEDKKYLASYIESF", "md5" : "68cecf8fd48955c8c7c1a9d3735ba839", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 973, "end" : 1007, "location-fragments" : [ { "start" : 973, "end" : 1007, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF02181", "name" : "FH2", "description" : "Formin Homology 2 Domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR015425", "name" : "FH2_Formin", "description" : "Formin, FH2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 597, "end" : 961, "hmmStart" : 4, "hmmEnd" : 371, "hmmLength" : 372, "hmmBounds" : "INCOMPLETE", "evalue" : 1.2E-83, "score" : 281.3, "envelopeStart" : 594, "envelopeEnd" : 962, "postProcessed" : true, "location-fragments" : [ { "start" : 597, "end" : 961, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-83, "score" : 281.3, "model-ac" : "PF02181" }, { "signature" : { "accession" : "PS51444", "name" : "FH2", "description" : "Formin homology-2 (FH2) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR015425", "name" : "FH2_Formin", "description" : "Formin, FH2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 594, "end" : 987, "score" : 43.954, "alignment" : "PLQSLTKTKKTVKLFWKEVcEDPIVMAKMNSSLIWdELTPVPVDTQKLEHLFESR----TKDLITKKQHELNKNKEIIVLDPKRSNAINIGMTKL-PPPRAIKTAILKMDATVMNREGIEKLLTMLPSEEERTKIQEAQTANPeLPLGSAEQFLLTLASIIELPARLKLWAFKLDYENSEKEIAEPLMDLKQGMELLKANKTFRAILATLLSIGIFLNGN----EVKGFQIEYLAKVPEVKDTVHKHSLLHHLCHMVMSKFPQSTDLYSEIGAVTRASKVDFDELALSIHRMEQECKASFDHLKVIVKH--DGSNAMKGKMSDFLADCAERIIVLCKVHRRVINRYHKFCLWLGIPLHrvcLTKPNELCRIISEFALEYRTTRERVLQQLEKKANHRERNKTRGK", "location-fragments" : [ { "start" : 594, "end" : 987, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51444" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1037, "end" : 1062, "location-fragments" : [ { "start" : 1037, "end" : 1062, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF48371", "name" : "ARM repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016024", "name" : "ARM-type_fold", "description" : "Armadillo-type fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 112, "end" : 327, "hmmLength" : 343, "location-fragments" : [ { "start" : 112, "end" : 327, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.12E-27, "model-ac" : "0052018" }, { "signature" : { "accession" : "SM00498", "name" : "it6_source", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR015425", "name" : "FH2_Formin", "description" : "Formin, FH2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 594, "end" : 1040, "hmmStart" : 1, "hmmEnd" : 499, "hmmLength" : 499, "hmmBounds" : "COMPLETE", "evalue" : 6.6E-59, "score" : 211.7, "location-fragments" : [ { "start" : 594, "end" : 1040, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-59, "score" : 211.7, "model-ac" : "SM00498" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1073, "end" : 1088, "location-fragments" : [ { "start" : 1073, "end" : 1088, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.25.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011989", "name" : "ARM-like", "description" : "Armadillo-like helical", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 327, "hmmStart" : 15, "hmmEnd" : 339, "hmmLength" : 339, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-159, "score" : 531.2, "envelopeStart" : 1, "envelopeEnd" : 327, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 327, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-159, "score" : 531.8, "model-ac" : "3dadA00" }, { "signature" : { "accession" : "G3DSA:1.20.58.2220", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042201", "name" : "FH2_Formin_sf", "description" : "Formin, FH2 domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 659, "end" : 991, "hmmStart" : 4, "hmmEnd" : 327, "hmmLength" : 340, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-80, "score" : 272.7, "envelopeStart" : 659, "envelopeEnd" : 991, "postProcessed" : true, "location-fragments" : [ { "start" : 659, "end" : 991, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.0E-81, "score" : 273.5, "model-ac" : "1v9dB00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 973, "end" : 1088, "location-fragments" : [ { "start" : 973, "end" : 1088, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF18382", "name" : "Formin_GBD_N", "description" : "Formin N-terminal GTPase-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR041387", "name" : "FHOD1_GBD_N", "description" : "FHOD1, N-terminal GTPase-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4, "end" : 103, "hmmStart" : 1, "hmmEnd" : 99, "hmmLength" : 99, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-42, "score" : 142.4, "envelopeStart" : 4, "envelopeEnd" : 103, "postProcessed" : true, "location-fragments" : [ { "start" : 4, "end" : 103, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-42, "score" : 144.0, "model-ac" : "PF18382" }, { "signature" : { "accession" : "PTHR45920", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 385, "hmmStart" : 3, "hmmEnd" : 349, "hmmLength" : 1165, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 10, "envelopeEnd" : 454, "location-fragments" : [ { "start" : 11, "end" : 385, "dc-status" : "CONTINUOUS" } ] }, { "start" : 459, "end" : 1110, "hmmStart" : 513, "hmmEnd" : 1161, "hmmLength" : 1165, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 450, "envelopeEnd" : 1113, "location-fragments" : [ { "start" : 459, "end" : 1110, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "FAMILY NOT NAMED", "score" : 1473.9, "model-ac" : "PTHR45920" }, { "signature" : { "accession" : "PS51232", "name" : "GBD_FH3", "description" : "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR014768", "name" : "GBD/FH3_dom", "description" : "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 49, "end" : 405, "score" : 20.755, "alignment" : "RLLHAPHRLDDAALQLYKDGDYSS---YLDLDATISEQQEEFEGFQSNR--------KNSIVLRTQLSVRVHTIIEKLLNSEGSELRRALFCLKqifqedKDLVHEFVQNDGLSCLIKVGSDANQN---------YQNYILRALGQVMLYVDGMNGVIEHNETIQWLYCLVSSKFRLVVKTALKLLLVFVEY-VESNCLLLIQAIHTVDKS-RGSLPWSNIMKLLNEYDVTDTELLIYAMTLINKTLNRVPDLDMYYDQVDEIEKQGIQEIVQRYMSrPGTDLDFLHQLQSYeAVLNHEDGGDKTIPLKQLDD-NVRTTRFSNASMISDIERRRSRRHSTGTVPLSLSVSPYNKANEDYHLKQAAEDGVGVTPALRRRLE", "location-fragments" : [ { "start" : 49, "end" : 405, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51232" }, { "signature" : { "accession" : "SSF101447", "name" : "Formin homology 2 domain (FH2 domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 578, "end" : 981, "hmmLength" : 411, "location-fragments" : [ { "start" : 578, "end" : 981, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.32E-85, "model-ac" : "0044554" } ], "xref" : [ { "name" : "XP_018909707.1 PREDICTED: FH1/FH2 domain-containing protein 3 isoform X6 [Bemisia tabaci]", "id" : "XP_018909707.1" } ] },{ "sequence" : "MVHEVKIGDMKLLTFVTVLSSASCCSAYNILVFSPYPTWSQYIQMEPLFSALGLRGHNVTVVSPFPPKKEQSHFHHIHFVADLYWKIKFSAPTSLKDWMAEIKDKRLPIDFWKELPDASMPEILESSVFQDLIHNENKFDLVFMEVFFGQEPLVVLGHLLDAPVVAFATFGHMPDILRYMGAPNAVAYLSHFNVDYAGSLILTQRLENAWIHYRTTLYDEYWYYPQHDAVLAKYFPGPLPSISDMLRNISLFFLTANTAVDGAKLYPPNVIELPVLHLKDPAPLDKELDVIMNNAQDGVIYFSFGSIVTPSILGEEETQIFLSVLKELNQTVLWKTDWNSTAHDIPKNVYTRDWFDQKSILAHPRCVLFLTHGGLSSLMEAINYAVPVVGMSVFGDQPKNLAYAEYLGYGLHIPHKDLTQNSLRRALRTVLQDGRFKENINRASKIFQDKPMSSLDTAIYWIEYAIRHKGAHHLKPLAVRMPWYQLFLLDIITVCFTIFVVLSYLMFKMISLLLRKYFTRSRPLKEKSN", "md5" : "65eb94a59d88ca2e0a7b3b9b789d68c0", "matches" : [ { "signature" : { "accession" : "cd03784", "name" : "GT1_Gtf-like", "description" : "GT1_Gtf-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 28, "end" : 459, "sites" : [ { "description" : "active site", "numLocations" : 14, "siteLocations" : [ { "start" : 196, "end" : 196, "residue" : "Y" }, { "start" : 372, "end" : 372, "residue" : "H" }, { "start" : 377, "end" : 377, "residue" : "S" }, { "start" : 41, "end" : 41, "residue" : "Q" }, { "start" : 380, "end" : 380, "residue" : "E" }, { "start" : 199, "end" : 199, "residue" : "S" }, { "start" : 204, "end" : 204, "residue" : "Q" }, { "start" : 43, "end" : 43, "residue" : "I" }, { "start" : 306, "end" : 306, "residue" : "S" }, { "start" : 374, "end" : 374, "residue" : "G" }, { "start" : 40, "end" : 40, "residue" : "S" }, { "start" : 376, "end" : 376, "residue" : "S" }, { "start" : 231, "end" : 231, "residue" : "L" }, { "start" : 200, "end" : 200, "residue" : "L" } ] }, { "description" : "acceptor substrate-binding pocket", "numLocations" : 1, "siteLocations" : [ { "start" : 41, "end" : 41, "residue" : "Q" } ] }, { "description" : "TDP-binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 372, "end" : 372, "residue" : "H" }, { "start" : 377, "end" : 377, "residue" : "S" }, { "start" : 306, "end" : 306, "residue" : "S" }, { "start" : 374, "end" : 374, "residue" : "G" }, { "start" : 40, "end" : 40, "residue" : "S" }, { "start" : 376, "end" : 376, "residue" : "S" } ] }, { "description" : "homodimer interface", "numLocations" : 5, "siteLocations" : [ { "start" : 28, "end" : 28, "residue" : "Y" }, { "start" : 140, "end" : 140, "residue" : "D" }, { "start" : 457, "end" : 457, "residue" : "T" }, { "start" : 55, "end" : 55, "residue" : "R" }, { "start" : 456, "end" : 456, "residue" : "D" } ] } ], "evalue" : 7.64167E-61, "score" : 203.937, "location-fragments" : [ { "start" : 28, "end" : 459, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd03784" }, { "signature" : { "accession" : "PTHR11926", "name" : "GLUCOSYL/GLUCURONOSYL TRANSFERASES", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 291, "end" : 401, "hmmStart" : 52, "hmmEnd" : 126, "hmmLength" : 134, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 129, "envelopeEnd" : 474, "location-fragments" : [ { "start" : 291, "end" : 401, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-14, "familyName" : "GLUCOSYL/GLUCURONOSYL TRANSFERASES", "score" : 55.5, "model-ac" : "PTHR11926" }, { "signature" : { "accession" : "G3DSA:3.40.50.2000", "name" : "Glycogen Phosphorylase B;", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 279, "end" : 449, "hmmStart" : 6, "hmmEnd" : 169, "hmmLength" : 170, "hmmBounds" : "COMPLETE", "evalue" : 2.0E-45, "score" : 156.3, "envelopeStart" : 279, "envelopeEnd" : 449, "postProcessed" : true, "location-fragments" : [ { "start" : 279, "end" : 449, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-45, "score" : 156.9, "model-ac" : "2o6lB00" }, { "signature" : { "accession" : "SSF53756", "name" : "UDP-Glycosyltransferase/glycogen phosphorylase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 28, "end" : 474, "hmmLength" : 471, "location-fragments" : [ { "start" : 28, "end" : 474, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-87, "model-ac" : "0054711" }, { "signature" : { "accession" : "PF00201", "name" : "UDPGT", "description" : "UDP-glucoronosyl and UDP-glucosyl transferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002213", "name" : "UDP_glucos_trans", "description" : "UDP-glucuronosyl/UDP-glucosyltransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "UDP-glycosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008194" } ], "pathwayXRefs" : [ { "name" : "Glucuronidation", "databaseName" : "Reactome", "id" : "R-HSA-156588" } ] } }, "locations" : [ { "start" : 40, "end" : 518, "hmmStart" : 11, "hmmEnd" : 493, "hmmLength" : 499, "hmmBounds" : "INCOMPLETE", "evalue" : 4.9E-66, "score" : 223.5, "envelopeStart" : 30, "envelopeEnd" : 522, "postProcessed" : true, "location-fragments" : [ { "start" : 40, "end" : 518, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-66, "score" : 224.3, "model-ac" : "PF00201" }, { "signature" : { "accession" : "PS51257", "name" : "PROKAR_LIPOPROTEIN", "description" : "Prokaryotic membrane lipoprotein lipid attachment site profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 24, "score" : 5.0, "alignment" : "MVHE-VK----------IGDMKLLTFVTVLSSASC", "location-fragments" : [ { "start" : 1, "end" : 24, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51257" } ], "xref" : [ { "name" : "XP_018910400.1 PREDICTED: UDP-glucuronosyltransferase 2C1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910400.1" } ] },{ "sequence" : "MGGLAGPEQQYSLRWNDYHASILSSFRHLRDEEDFVDVTLACDGRSFTAHKVVLSACSPYFRTLLKANPCQHPIVILRDVREQDMKALLKFMYNGEVHIGEEQLPDFLKTAQTLQVRGLADVPGKEHPKFNPSGPNPVPWSVPSAESRLGGDEGMTPPPVKRSRSSDHMTSPSPSTTPNNISTPNNNNNNIESNQNNNCRDLILSQALENPSQLLNNSNMTIKLTSESSLHAHSTGEDSNSSDTELSERGHSVTGDGVKSEPNSDFNDHGSHPMDHARPPPNFPAALLGLQGLPGLLPGPSGMHGNNQDSNFGPSWMADYGGGSDFMGHYQSTPSSMGPQKPVCPECGKVYSNNSNLKQHIANVHAQQDRTETCYVCHKQFKTKQYLQVHLLASHGIRQRNPVSWLK", "md5" : "c25ab070840fb88a88c3ac5840ce2ff3", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 163, "end" : 204, "location-fragments" : [ { "start" : 163, "end" : 204, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 343, "end" : 391, "hmmLength" : 53, "location-fragments" : [ { "start" : 343, "end" : 391, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.14E-7, "model-ac" : "0052279" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 342, "end" : 370, "score" : 10.928, "alignment" : "PVCPECGKVYSNNSNLKQHIAnVHAQQDR", "location-fragments" : [ { "start" : 342, "end" : 370, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "PF00651", "name" : "BTB", "description" : "BTB/POZ domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000210", "name" : "BTB/POZ_dom", "description" : "BTB/POZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 27, "end" : 121, "hmmStart" : 2, "hmmEnd" : 101, "hmmLength" : 111, "hmmBounds" : "INCOMPLETE", "evalue" : 1.0E-25, "score" : 90.1, "envelopeStart" : 26, "envelopeEnd" : 126, "postProcessed" : true, "location-fragments" : [ { "start" : 27, "end" : 121, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-26, "score" : 91.0, "model-ac" : "PF00651" }, { "signature" : { "accession" : "G3DSA:3.30.160.60", "name" : "Classic Zinc Finger", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 328, "end" : 401, "hmmStart" : 32, "hmmEnd" : 87, "hmmLength" : 96, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-11, "score" : 46.5, "envelopeStart" : 328, "envelopeEnd" : 401, "postProcessed" : true, "location-fragments" : [ { "start" : 328, "end" : 401, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-11, "score" : 46.5, "model-ac" : "2ctdA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 226, "end" : 291, "location-fragments" : [ { "start" : 226, "end" : 291, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 226, "end" : 241, "location-fragments" : [ { "start" : 226, "end" : 241, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd18315", "name" : "BTB_POZ_BAB-like", "description" : "BTB_POZ_BAB-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 118, "sites" : [ ], "evalue" : 7.15442E-40, "score" : 134.985, "location-fragments" : [ { "start" : 35, "end" : 118, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18315" }, { "signature" : { "accession" : "SM00225", "name" : "BTB_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000210", "name" : "BTB/POZ_dom", "description" : "BTB/POZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 36, "end" : 131, "hmmStart" : 1, "hmmEnd" : 114, "hmmLength" : 114, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-23, "score" : 94.0, "location-fragments" : [ { "start" : 36, "end" : 131, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-23, "score" : 94.0, "model-ac" : "SM00225" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 374, "end" : 395, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M4I1M", "alignment" : "CyvChkqFktkqylqvHllasH", "location-fragments" : [ { "start" : 374, "end" : 395, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 118, "end" : 204, "location-fragments" : [ { "start" : 118, "end" : 204, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00355", "name" : "c2h2final6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 342, "end" : 365, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.0094, "score" : 25.1, "location-fragments" : [ { "start" : 342, "end" : 365, "dc-status" : "CONTINUOUS" } ] }, { "start" : 372, "end" : 395, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 0.83, "score" : 18.7, "location-fragments" : [ { "start" : 372, "end" : 395, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-8, "score" : 43.8, "model-ac" : "SM00355" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 344, "end" : 365, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M4I1M", "alignment" : "CpeCgkvYsnnsnlkqHianvH", "location-fragments" : [ { "start" : 344, "end" : 365, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PTHR23110:SF98", "name" : "PROTEIN ABRUPT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 395, "hmmStart" : 2, "hmmEnd" : 337, "hmmLength" : 578, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 404, "location-fragments" : [ { "start" : 9, "end" : 395, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.1E-109, "familyName" : "PROTEIN ABRUPT", "score" : 367.9, "model-ac" : "PTHR23110:SF98" }, { "signature" : { "accession" : "PTHR23110", "name" : "BTB DOMAIN TRANSCRIPTION FACTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 395, "hmmStart" : 2, "hmmEnd" : 337, "hmmLength" : 578, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 404, "location-fragments" : [ { "start" : 9, "end" : 395, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.1E-109, "familyName" : "PROTEIN ABRUPT", "score" : 367.9, "model-ac" : "PTHR23110" }, { "signature" : { "accession" : "SSF54695", "name" : "POZ domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011333", "name" : "SKP1/BTB/POZ_sf", "description" : "SKP1/BTB/POZ domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 9, "end" : 121, "hmmLength" : 121, "location-fragments" : [ { "start" : 9, "end" : 121, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.83E-30, "model-ac" : "0035720" }, { "signature" : { "accession" : "PF00096", "name" : "zf-C2H2", "description" : "Zinc finger, C2H2 type", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 343, "end" : 365, "hmmStart" : 2, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.4E-5, "score" : 25.3, "envelopeStart" : 343, "envelopeEnd" : 365, "postProcessed" : true, "location-fragments" : [ { "start" : 343, "end" : 365, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-10, "score" : 40.3, "model-ac" : "PF00096" }, { "signature" : { "accession" : "G3DSA:3.30.710.10", "name" : "Potassium Channel Kv1.1; Chain A", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 136, "hmmStart" : 9, "hmmEnd" : 112, "hmmLength" : 156, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-32, "score" : 114.5, "envelopeStart" : 12, "envelopeEnd" : 136, "postProcessed" : true, "location-fragments" : [ { "start" : 12, "end" : 136, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.1E-33, "score" : 115.6, "model-ac" : "4u2nA01" }, { "signature" : { "accession" : "PS50097", "name" : "BTB", "description" : "BTB domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000210", "name" : "BTB/POZ_dom", "description" : "BTB/POZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 36, "end" : 101, "score" : 22.071, "alignment" : "VDVTLACDGRSFTAHKVVLSACSPYFRTLLKANPCQHP-IVILRDVREQDMKALLKFMYNGEVHIGE", "location-fragments" : [ { "start" : 36, "end" : 101, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50097" } ], "xref" : [ { "name" : "XP_018909633.1 PREDICTED: protein abrupt-like isoform X3 [Bemisia tabaci]", "id" : "XP_018909633.1" } ] },{ "sequence" : "MEVSSDRRRNDLSQRKTASKKMQTLSQDGHGETDKSSESLSRSGKTQNPKVKKRAIEVVTQSSGTTCNALSTESAKAKKIKLRNLSHQTGNTFKIALNPISVPDDSIVKVEREDSSNLSCTEEMEVSDSVVVSNNIRIKQEMEESNEDWQHDLNCLWEPVEIEHCEQNVNPSSNVSRLENTIAGEEIENSSPALNSPEYNGSSKRTLNYVKMYREGTLRAMADIANEHAALAAKSNDPVEPVQPKKIIPLEFLDKKPKVSDQMKLSILEEAKTNFEEATLKQSNNPIEPVQARKITPRGYLGKKPKFSHQIKLSILEEAKANFEGATFKQSNNPVEPVRARKTIPRGVLAMKPKVSHEIKLTILKEAKTNFAQIASCSKENDEGKIVTSVMSKQDGRRQSYFTEPSLGNLPSLKESIDLRKPESFDIIDKTEIEECVKVFIKEEPISEEFIEQNSVGSETEFSLKHCNDEWERHSDFQVLEDDEKLRKCAQVARKLAQTLKAGIEWVKPLVDEFDKKKMKRISKKDKEESILECKLAILKIDKAQKLALKHLCIVHFLNPINKNVNSLMHPNSENKEDKVEELSRRMAEFSEIVDTLANKKEGKKLSQELKESVKLLETVKLFEKSVKEELAILEKDTPKSPPKSPPKSLPLKDVSKNKRSRRSKRTIKKEKMSEPCVKGLSLDKVHVMPSQLLKIATLSKNFYPQRIKKSWELEEQEREEKMKLEQEMAKQQLAAMNLSSECVQKGKSLTKHAQTTEIVIKINTAEEKVTNAQSKKSPKHSKMLGQKSSSRIC", "md5" : "b17c63672253517b02e1eb26d2912a2a", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 768, "end" : 794, "location-fragments" : [ { "start" : 768, "end" : 794, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 573, "end" : 600, "location-fragments" : [ { "start" : 573, "end" : 600, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 634, "end" : 673, "location-fragments" : [ { "start" : 634, "end" : 673, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 57, "location-fragments" : [ { "start" : 1, "end" : 57, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 715, "end" : 742, "location-fragments" : [ { "start" : 715, "end" : 742, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 16, "location-fragments" : [ { "start" : 1, "end" : 16, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909682.1 PREDICTED: uncharacterized protein LOC109038885 [Bemisia tabaci]", "id" : "XP_018909682.1" }, { "name" : "XP_018909680.1 PREDICTED: uncharacterized protein LOC109038885 [Bemisia tabaci]", "id" : "XP_018909680.1" }, { "name" : "XP_018909681.1 PREDICTED: uncharacterized protein LOC109038885 [Bemisia tabaci]", "id" : "XP_018909681.1" } ] },{ "sequence" : "MLTPMLFLDQHNPPLAALHSMTEMKTSPNGGNPHGIDHILARPAGLSYRPFNSVAGVAAAAASYFQQNGAKPHGLVDFSTRSPIYWPGLQGLVNNPMAWRDRLASLSSNNDKDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKKHAAEMATAKRKQEEAEESDEDGELRSSGASAGKKFRRELGAHCGTPLM", "md5" : "d32a0b41ad8993a5cb28ba6f63dc03d8", "matches" : [ { "signature" : { "accession" : "PR00024", "name" : "HOMEOBOX", "description" : "Homeobox signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR020479", "name" : "Homeobox_metazoa", "description" : "Homeobox domain, metazoa", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 138, "end" : 149, "pvalue" : 6.8E-4, "score" : 37.5, "motifNumber" : 1, "location-fragments" : [ { "start" : 138, "end" : 149, "dc-status" : "CONTINUOUS" } ] }, { "start" : 153, "end" : 163, "pvalue" : 1.14E-4, "score" : 51.41, "motifNumber" : 2, "location-fragments" : [ { "start" : 153, "end" : 163, "dc-status" : "CONTINUOUS" } ] }, { "start" : 163, "end" : 172, "pvalue" : 2.3E-5, "score" : 73.73, "motifNumber" : 3, "location-fragments" : [ { "start" : 163, "end" : 172, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-6, "graphscan" : "III", "model-ac" : "PR00024" }, { "signature" : { "accession" : "PF00046", "name" : "Homeodomain", "description" : "Homeodomain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001356", "name" : "Homeobox_dom", "description" : "Homeobox domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 118, "end" : 173, "hmmStart" : 2, "hmmEnd" : 57, "hmmLength" : 57, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.5E-20, "score" : 72.8, "envelopeStart" : 117, "envelopeEnd" : 173, "postProcessed" : true, "location-fragments" : [ { "start" : 118, "end" : 173, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-21, "score" : 73.5, "model-ac" : "PF00046" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 180, "end" : 214, "location-fragments" : [ { "start" : 180, "end" : 214, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 172, "end" : 192, "location-fragments" : [ { "start" : 172, "end" : 192, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PS00027", "name" : "HOMEOBOX_1", "description" : "'Homeobox' domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017970", "name" : "Homeobox_CS", "description" : "Homeobox, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "DNA-binding transcription factor activity, RNA polymerase II-specific", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0000981" }, { "name" : "regulation of transcription, DNA-templated", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006355" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 149, "end" : 172, "level" : "STRONG", "cigarAlignment" : "2M2I1M1I2M2I6M1I1M5I1M", "alignment" : "LAyaLgMSesQVKVWFqNrrtkwR", "location-fragments" : [ { "start" : 149, "end" : 172, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00027" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 176, "end" : 222, "location-fragments" : [ { "start" : 176, "end" : 222, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PR00031", "name" : "HTHREPRESSR", "description" : "Lambda-repressor HTH signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000047", "name" : "HTH_motif", "description" : "Helix-turn-helix motif", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 145, "end" : 154, "pvalue" : 2.12E-4, "score" : 51.07, "motifNumber" : 1, "location-fragments" : [ { "start" : 145, "end" : 154, "dc-status" : "CONTINUOUS" } ] }, { "start" : 154, "end" : 170, "pvalue" : 2.51E-9, "score" : 57.8, "motifNumber" : 2, "location-fragments" : [ { "start" : 154, "end" : 170, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-6, "graphscan" : "II", "model-ac" : "PR00031" }, { "signature" : { "accession" : "cd00086", "name" : "homeodomain", "description" : "homeodomain", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR001356", "name" : "Homeobox_dom", "description" : "Homeobox domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 117, "end" : 175, "sites" : [ { "description" : "DNA binding site", "numLocations" : 18, "siteLocations" : [ { "start" : 173, "end" : 173, "residue" : "K" }, { "start" : 121, "end" : 121, "residue" : "P" }, { "start" : 161, "end" : 161, "residue" : "K" }, { "start" : 140, "end" : 140, "residue" : "Y" }, { "start" : 120, "end" : 120, "residue" : "R" }, { "start" : 168, "end" : 168, "residue" : "R" }, { "start" : 170, "end" : 170, "residue" : "K" }, { "start" : 169, "end" : 169, "residue" : "T" }, { "start" : 117, "end" : 117, "residue" : "K" }, { "start" : 119, "end" : 119, "residue" : "T" }, { "start" : 162, "end" : 162, "residue" : "V" }, { "start" : 172, "end" : 172, "residue" : "R" }, { "start" : 159, "end" : 159, "residue" : "Q" }, { "start" : 166, "end" : 166, "residue" : "N" }, { "start" : 118, "end" : 118, "residue" : "H" }, { "start" : 123, "end" : 123, "residue" : "F" }, { "start" : 146, "end" : 146, "residue" : "R" }, { "start" : 165, "end" : 165, "residue" : "Q" } ] }, { "description" : "specific DNA base contacts", "numLocations" : 6, "siteLocations" : [ { "start" : 169, "end" : 169, "residue" : "T" }, { "start" : 119, "end" : 119, "residue" : "T" }, { "start" : 162, "end" : 162, "residue" : "V" }, { "start" : 166, "end" : 166, "residue" : "N" }, { "start" : 122, "end" : 122, "residue" : "T" }, { "start" : 165, "end" : 165, "residue" : "Q" } ] } ], "evalue" : 1.43149E-20, "score" : 79.5948, "location-fragments" : [ { "start" : 117, "end" : 175, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00086" }, { "signature" : { "accession" : "G3DSA:1.10.10.60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 104, "end" : 177, "hmmStart" : 9, "hmmEnd" : 75, "hmmLength" : 80, "hmmBounds" : "COMPLETE", "evalue" : 5.8E-25, "score" : 88.8, "envelopeStart" : 104, "envelopeEnd" : 177, "postProcessed" : true, "location-fragments" : [ { "start" : 104, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-25, "score" : 89.7, "model-ac" : "2dmtA00" }, { "signature" : { "accession" : "PTHR24340:SF21", "name" : "HOMEOBOX PROTEIN NKX-6.2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 20, "end" : 196, "hmmStart" : 44, "hmmEnd" : 227, "hmmLength" : 274, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 211, "location-fragments" : [ { "start" : 20, "end" : 196, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-63, "familyName" : "HOMEOBOX PROTEIN NKX-6.2", "score" : 216.0, "model-ac" : "PTHR24340:SF21" }, { "signature" : { "accession" : "SSF46689", "name" : "Homeodomain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009057", "name" : "Homeobox-like_sf", "description" : "Homeobox-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 97, "end" : 174, "hmmLength" : 88, "location-fragments" : [ { "start" : 97, "end" : 174, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.41E-24, "model-ac" : "0045889" }, { "signature" : { "accession" : "PS50071", "name" : "HOMEOBOX_2", "description" : "'Homeobox' domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001356", "name" : "Homeobox_dom", "description" : "Homeobox domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 114, "end" : 174, "score" : 19.791, "alignment" : "GKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKK", "location-fragments" : [ { "start" : 114, "end" : 174, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50071" }, { "signature" : { "accession" : "SM00389", "name" : "HOX_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001356", "name" : "Homeobox_dom", "description" : "Homeobox domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 116, "end" : 178, "hmmStart" : 1, "hmmEnd" : 63, "hmmLength" : 63, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-23, "score" : 94.2, "location-fragments" : [ { "start" : 116, "end" : 178, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-23, "score" : 94.2, "model-ac" : "SM00389" }, { "signature" : { "accession" : "PTHR24340", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 20, "end" : 196, "hmmStart" : 44, "hmmEnd" : 227, "hmmLength" : 274, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 211, "location-fragments" : [ { "start" : 20, "end" : 196, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-63, "familyName" : "HOMEOBOX PROTEIN NKX-6.2", "score" : 216.0, "model-ac" : "PTHR24340" } ], "xref" : [ { "name" : "XP_018909938.1 PREDICTED: homeobox protein Nkx-6.2-like [Bemisia tabaci]", "id" : "XP_018909938.1" } ] },{ "sequence" : "MFEDLAERHGPSKKTIVFIVYVSLFLDNTLLTVVVPIIPDYLFHIENPYSDVLTNISRTTTTNVNEIAKKALVEMEKDLRAENGQVGLLLSSKALLQLIMNPIVGVLSPRLGVHLSLFIGSVSLLVAALIFALGESFIELLIGRSLQGIASACIGVAGMSLVAQEYPEDKERSHVMGIVLGSVALGVLLGYPLGGLLYDISGKSTPFFVVAFAVLCDLGLQVHYLNFESKFEPSVGVWGWSHMLSHRLVVLISGALLFSTVAMAVLEPCLPLWLMSHIKPKKWQLGLVFIPDSVGYLISTNFFGPLAYKVGRWQVVVISMLIIGVSTFMLPQSKSMLALITPHFLLGLGIGAVDAALVPLLASLVDASLYSSVYALQQMAVSLAYFIGPMIGGELVRAIGFPWLLRVVGLLNILYCCLIVFCVKNKRIEDDMLRVQWVKYTSYRTAESSENGSNENVNQRGPPFQRFINGDDSD", "md5" : "78e3ea28ee2f9d32e09d25f7b00a78eb", "matches" : [ { "signature" : { "accession" : "cd17384", "name" : "MFS_SLC18A1_2_VAT1_2", "description" : "MFS_SLC18A1_2_VAT1_2", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 422, "sites" : [ { "description" : "putative chemical substrate binding pocket", "numLocations" : 35, "siteLocations" : [ { "start" : 382, "end" : 382, "residue" : "S" }, { "start" : 353, "end" : 353, "residue" : "V" }, { "start" : 377, "end" : 377, "residue" : "Q" }, { "start" : 183, "end" : 183, "residue" : "V" }, { "start" : 354, "end" : 354, "residue" : "D" }, { "start" : 155, "end" : 155, "residue" : "G" }, { "start" : 362, "end" : 362, "residue" : "A" }, { "start" : 27, "end" : 27, "residue" : "D" }, { "start" : 152, "end" : 152, "residue" : "A" }, { "start" : 184, "end" : 184, "residue" : "A" }, { "start" : 154, "end" : 154, "residue" : "I" }, { "start" : 378, "end" : 378, "residue" : "Q" }, { "start" : 35, "end" : 35, "residue" : "V" }, { "start" : 101, "end" : 101, "residue" : "N" }, { "start" : 259, "end" : 259, "residue" : "S" }, { "start" : 358, "end" : 358, "residue" : "V" }, { "start" : 31, "end" : 31, "residue" : "L" }, { "start" : 256, "end" : 256, "residue" : "L" }, { "start" : 156, "end" : 156, "residue" : "V" }, { "start" : 300, "end" : 300, "residue" : "T" }, { "start" : 151, "end" : 151, "residue" : "S" }, { "start" : 296, "end" : 296, "residue" : "Y" }, { "start" : 180, "end" : 180, "residue" : "L" }, { "start" : 263, "end" : 263, "residue" : "M" }, { "start" : 32, "end" : 32, "residue" : "T" }, { "start" : 187, "end" : 187, "residue" : "V" }, { "start" : 264, "end" : 264, "residue" : "A" }, { "start" : 265, "end" : 265, "residue" : "V" }, { "start" : 260, "end" : 260, "residue" : "T" }, { "start" : 268, "end" : 268, "residue" : "P" }, { "start" : 381, "end" : 381, "residue" : "V" }, { "start" : 374, "end" : 374, "residue" : "Y" }, { "start" : 159, "end" : 159, "residue" : "M" }, { "start" : 28, "end" : 28, "residue" : "N" }, { "start" : 385, "end" : 385, "residue" : "Y" } ] } ], "evalue" : 0.0, "score" : 513.659, "location-fragments" : [ { "start" : 16, "end" : 422, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd17384" }, { "signature" : { "accession" : "PS50850", "name" : "MFS", "description" : "Major facilitator superfamily (MFS) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR020846", "name" : "MFS_dom", "description" : "Major facilitator superfamily domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 16, "end" : 427, "score" : 21.182, "alignment" : "IVFIVYVSLFLDNTLLTVVvpiipdylfhienpysdvltnisrttttnvneiaKKALVEMEKDLRAENGQVGLLLSSKALLQLIMNPIVGVLSPRLGVHLSLFIGSVSLLVAALIFALGESFIELLIGRSLQGIASACIGVAGMSLVAQEYPEDKeRSHVMGIVLGSVALGVLLGYPLGGLLYDISGKSTPFFVV-AFAVLCDLGLQvHYLNFESKF---EPSVGVWGWSHMLSHRLVVL----ISGALLFSTVA----MAVLEPCLPLWLMSHIkPKKWQLGLVFIPDSVGY---LISTNFFGPLAYKVGRWQVVVISMLIIGVSTFMLPQSKS---MLALITPHFLLGLGIGAVDAALVPLLASLVDASLYSSVYALQQMAVSLAYFIGPMIGGELVRAIGFPWLLRVVGLLNILYCCLIVFCVKNKR", "location-fragments" : [ { "start" : 16, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50850" }, { "signature" : { "accession" : "PTHR23506:SF4", "name" : "PORTABELLA", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 455, "hmmStart" : 10, "hmmEnd" : 475, "hmmLength" : 481, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 460, "location-fragments" : [ { "start" : 12, "end" : 455, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-155, "familyName" : "PORTABELLA", "score" : 521.7, "model-ac" : "PTHR23506:SF4" }, { "signature" : { "accession" : "G3DSA:1.20.1250.20", "name" : "MFS general substrate transporter like domains", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 245, "end" : 459, "hmmStart" : 8, "hmmEnd" : 183, "hmmLength" : 427, "hmmBounds" : "COMPLETE", "evalue" : 6.2E-24, "score" : 86.6, "envelopeStart" : 245, "envelopeEnd" : 459, "postProcessed" : true, "location-fragments" : [ { "start" : 245, "end" : 459, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-48, "score" : 166.7, "model-ac" : "4ldsA00" }, { "signature" : { "accession" : "PTHR23506", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 455, "hmmStart" : 10, "hmmEnd" : 475, "hmmLength" : 481, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 460, "location-fragments" : [ { "start" : 12, "end" : 455, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-155, "familyName" : "PORTABELLA", "score" : 521.7, "model-ac" : "PTHR23506" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 449, "end" : 474, "location-fragments" : [ { "start" : 449, "end" : 474, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF103473", "name" : "MFS general substrate transporter", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036259", "name" : "MFS_trans_sf", "description" : "MFS transporter superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 427, "hmmLength" : 417, "location-fragments" : [ { "start" : 78, "end" : 427, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 13, "end" : 43, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 6.93E-57, "model-ac" : "0042480" }, { "signature" : { "accession" : "PF07690", "name" : "MFS_1", "description" : "Major Facilitator Superfamily", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR011701", "name" : "MFS", "description" : "Major facilitator superfamily", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 255, "end" : 423, "hmmStart" : 4, "hmmEnd" : 172, "hmmLength" : 353, "hmmBounds" : "INCOMPLETE", "evalue" : 1.2E-17, "score" : 63.9, "envelopeStart" : 251, "envelopeEnd" : 460, "postProcessed" : true, "location-fragments" : [ { "start" : 255, "end" : 423, "dc-status" : "CONTINUOUS" } ] }, { "start" : 17, "end" : 215, "hmmStart" : 1, "hmmEnd" : 162, "hmmLength" : 353, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.7E-26, "score" : 91.0, "envelopeStart" : 17, "envelopeEnd" : 236, "postProcessed" : true, "location-fragments" : [ { "start" : 17, "end" : 215, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-43, "score" : 149.2, "model-ac" : "PF07690" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 65, "end" : 85, "location-fragments" : [ { "start" : 65, "end" : 85, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 449, "end" : 463, "location-fragments" : [ { "start" : 449, "end" : 463, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909911.1 PREDICTED: synaptic vesicular amine transporter-like [Bemisia tabaci]", "id" : "XP_018909911.1" } ] },{ "sequence" : "MTEALSSSSAGERRLKELEALFLGGPIQGRGQCFSIETLLDILLVLYDECTNSSLRREKTVSEFIEFVKPVATCVKNLRLSRDDFEMVKVIGRGAFGEVFVVRMKGSEKVFAMKILNKWEMLRRAEIACFQEERDVLVYGDRRWITNLHYAFQDEANLYLVMDYYCGGDLLTLLSKFEDRLPEDMARFYIAEMVLAISSVHDLRYVHRDIKPDNVLLDANGHIRLADFGSCLKLSEDGTVQSNVAVGTPDYISPEILRAMEDGQGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKNCFDFPSDLPVEVTNDAKDLMKRLICSAEYRLGQNGVEDFKNHAWFLGIDWSSLRDSTAPYLPEVSSPTDTSNFDVDDMDIRTSDSVPPTASNPAFTGLHLPFVGFTFTQGSRVGDLGCITFSDSNIRMSAGGKRMRLHEDQLDCKAEPLNNARKISPTSESTGTNLRKLQDEINTLTKRNCELESELQDLEGHERVRELEKLMRLLKQEKEEVNKEKVEVEEKLKLQEKELKDAVSQKKIAMAEYSEVSDKLSDLRQQKQKLSRIVRDKEEELEQAMQKIDSLRQDMRRGEKLRRELEARIDEAMQEATKERKLRERSEEYCNQLKAEWKQLKERRDTGSGDGSSAISQHNIQEINRLKTELETLEVEYSDNLSQQQARHREEINNLREQLLEAEARKEVLEKEVAAAKEKLDTARLESITENEEALATLARRHDSEKMRLLEENKRLALDVDTLNAGRLQETEMGNKKESIAQWEAQISEIIQWVNDEKDARGYLQALATKMTEELEYLKHTAVSTNTVDKSWRNRRSQKLEKMELLNLQSSLQSEIQAKQTIGDELSRTRAELIAAQKELREFHQRFDNLVVDVKRKEIQLKELQARLDSGEGFERKNLVLERPGSQMSYLDHFLKESSVTRQLRDSITSEEGNLDDNQTLSVASSKTNLSDMNMEQSSLKLQPRVLSSNMMIAKSHQFLIRTFSAPTKCNHCTSLMIGLTRQGVVCEVCGFACHTTCCDKVPIACPVPPDQTKRPLGIDPTRGIGTAYEGYVKVPRAGGVKKGWVRQFVVVCDFKLFLYDISADRNALPSVQVSQVLDMRDEHFSVSSVRESDVIHAMKKDIPCIFRITTSLLEPSELQNHTLMLADTESEKSKWVVALSELHRILKRNNLPNTTVFKAKQVMDSTLRAVMSGAIVDPDRLVIGTEDGLFCLDLDHSEMARVGEGKKVFEMEYIEKEQLLLVLSGKQRHVRLIPVRALDGDEVEWIKVTESKGCITFAVGQLSRNVHCLCVAIKRQNTSQIIIYEITRTRQRHKRMREVMIPTQVQTVQVLSEARLCVGYQSGFSIYNISGDHLAMPLIGTDNPVASFLSYSNSEALKCIELPRGEFLLVFQTLGIYVDSQGRKSRDKEIMYPAYPIAVSYSDGYLLVFSEIHVDVFNVETGDWVQTLNTKRALPLDTHGSLAICLVNDLTHLIYLHNLHQRELLNLTTFDASGREIPRTRRRFSLREGNRASRAPDRRSKMISAPSNFNHISHMGPGDGIQVQRLLDLPTTIETADNAPSPYPKVLHAPPVPLKMSHPPPRHPPPRIPMHPPHNGSSIRRAPAPPRPTPDSVSLYHDFKDQNTSPRHSIASNNSSNPSTPPSPGRDSSCDS", "md5" : "0e6ea89a1c34a16ac9a992c693ed04a2", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 473, "end" : 493, "location-fragments" : [ { "start" : 473, "end" : 493, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "cd05597", "name" : "STKc_DMPK_like", "description" : "STKc_DMPK_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 83, "end" : 415, "sites" : [ { "description" : "ATP binding site", "numLocations" : 20, "siteLocations" : [ { "start" : 164, "end" : 164, "residue" : "Y" }, { "start" : 92, "end" : 92, "residue" : "G" }, { "start" : 114, "end" : 114, "residue" : "K" }, { "start" : 163, "end" : 163, "residue" : "D" }, { "start" : 227, "end" : 227, "residue" : "D" }, { "start" : 112, "end" : 112, "residue" : "A" }, { "start" : 165, "end" : 165, "residue" : "Y" }, { "start" : 169, "end" : 169, "residue" : "D" }, { "start" : 91, "end" : 91, "residue" : "I" }, { "start" : 95, "end" : 95, "residue" : "A" }, { "start" : 216, "end" : 216, "residue" : "L" }, { "start" : 209, "end" : 209, "residue" : "D" }, { "start" : 214, "end" : 214, "residue" : "N" }, { "start" : 146, "end" : 146, "residue" : "T" }, { "start" : 211, "end" : 211, "residue" : "K" }, { "start" : 94, "end" : 94, "residue" : "G" }, { "start" : 213, "end" : 213, "residue" : "D" }, { "start" : 93, "end" : 93, "residue" : "R" }, { "start" : 99, "end" : 99, "residue" : "V" }, { "start" : 226, "end" : 226, "residue" : "A" } ] }, { "description" : "polypeptide substrate binding site", "numLocations" : 16, "siteLocations" : [ { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 169, "end" : 169, "residue" : "D" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 95, "end" : 95, "residue" : "A" }, { "start" : 249, "end" : 249, "residue" : "P" }, { "start" : 291, "end" : 291, "residue" : "Y" }, { "start" : 282, "end" : 282, "residue" : "E" }, { "start" : 245, "end" : 245, "residue" : "A" }, { "start" : 288, "end" : 288, "residue" : "T" }, { "start" : 230, "end" : 230, "residue" : "S" }, { "start" : 209, "end" : 209, "residue" : "D" }, { "start" : 250, "end" : 250, "residue" : "D" }, { "start" : 171, "end" : 171, "residue" : "L" }, { "start" : 211, "end" : 211, "residue" : "K" }, { "start" : 213, "end" : 213, "residue" : "D" }, { "start" : 248, "end" : 248, "residue" : "T" } ] }, { "description" : "activation loop (A-loop)", "numLocations" : 23, "siteLocations" : [ { "start" : 234, "end" : 234, "residue" : "L" }, { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 227, "end" : 227, "residue" : "D" }, { "start" : 228, "end" : 228, "residue" : "F" }, { "start" : 236, "end" : 236, "residue" : "E" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 239, "end" : 239, "residue" : "T" }, { "start" : 249, "end" : 249, "residue" : "P" }, { "start" : 242, "end" : 242, "residue" : "S" }, { "start" : 229, "end" : 229, "residue" : "G" }, { "start" : 240, "end" : 240, "residue" : "V" }, { "start" : 245, "end" : 245, "residue" : "A" }, { "start" : 235, "end" : 235, "residue" : "S" }, { "start" : 230, "end" : 230, "residue" : "S" }, { "start" : 232, "end" : 232, "residue" : "L" }, { "start" : 244, "end" : 244, "residue" : "V" }, { "start" : 241, "end" : 241, "residue" : "Q" }, { "start" : 243, "end" : 243, "residue" : "N" }, { "start" : 250, "end" : 250, "residue" : "D" }, { "start" : 231, "end" : 231, "residue" : "C" }, { "start" : 226, "end" : 226, "residue" : "A" }, { "start" : 233, "end" : 233, "residue" : "K" }, { "start" : 248, "end" : 248, "residue" : "T" } ] }, { "description" : "active site", "numLocations" : 31, "siteLocations" : [ { "start" : 92, "end" : 92, "residue" : "G" }, { "start" : 114, "end" : 114, "residue" : "K" }, { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 163, "end" : 163, "residue" : "D" }, { "start" : 227, "end" : 227, "residue" : "D" }, { "start" : 162, "end" : 162, "residue" : "M" }, { "start" : 165, "end" : 165, "residue" : "Y" }, { "start" : 95, "end" : 95, "residue" : "A" }, { "start" : 249, "end" : 249, "residue" : "P" }, { "start" : 291, "end" : 291, "residue" : "Y" }, { "start" : 245, "end" : 245, "residue" : "A" }, { "start" : 209, "end" : 209, "residue" : "D" }, { "start" : 250, "end" : 250, "residue" : "D" }, { "start" : 214, "end" : 214, "residue" : "N" }, { "start" : 146, "end" : 146, "residue" : "T" }, { "start" : 211, "end" : 211, "residue" : "K" }, { "start" : 94, "end" : 94, "residue" : "G" }, { "start" : 99, "end" : 99, "residue" : "V" }, { "start" : 226, "end" : 226, "residue" : "A" }, { "start" : 112, "end" : 112, "residue" : "A" }, { "start" : 169, "end" : 169, "residue" : "D" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 91, "end" : 91, "residue" : "I" }, { "start" : 282, "end" : 282, "residue" : "E" }, { "start" : 288, "end" : 288, "residue" : "T" }, { "start" : 230, "end" : 230, "residue" : "S" }, { "start" : 216, "end" : 216, "residue" : "L" }, { "start" : 171, "end" : 171, "residue" : "L" }, { "start" : 213, "end" : 213, "residue" : "D" }, { "start" : 93, "end" : 93, "residue" : "R" }, { "start" : 248, "end" : 248, "residue" : "T" } ] }, { "description" : "hydrophobic motif (HM)", "numLocations" : 6, "siteLocations" : [ { "start" : 409, "end" : 409, "residue" : "F" }, { "start" : 414, "end" : 414, "residue" : "F" }, { "start" : 412, "end" : 412, "residue" : "F" }, { "start" : 410, "end" : 410, "residue" : "V" }, { "start" : 413, "end" : 413, "residue" : "T" }, { "start" : 411, "end" : 411, "residue" : "G" } ] } ], "evalue" : 0.0, "score" : 734.153, "location-fragments" : [ { "start" : 83, "end" : 415, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd05597" }, { "signature" : { "accession" : "G3DSA:1.10.510.10", "name" : "Transferase(Phosphotransferase) domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 171, "end" : 374, "hmmStart" : 3, "hmmEnd" : 363, "hmmLength" : 363, "hmmBounds" : "INCOMPLETE", "evalue" : 9.0E-187, "score" : 622.1, "envelopeStart" : 16, "envelopeEnd" : 382, "postProcessed" : true, "location-fragments" : [ { "start" : 171, "end" : 374, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-187, "score" : 623.7, "model-ac" : "3tkuA02" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 61, "end" : 403, "hmmLength" : 353, "location-fragments" : [ { "start" : 61, "end" : 403, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.01E-80, "model-ac" : "0040180" }, { "signature" : { "accession" : "G3DSA:3.30.200.20", "name" : "Phosphorylase Kinase; domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 382, "hmmStart" : 3, "hmmEnd" : 363, "hmmLength" : 213, "hmmBounds" : "INCOMPLETE", "evalue" : 9.0E-187, "score" : 622.1, "envelopeStart" : 16, "envelopeEnd" : 382, "postProcessed" : true, "location-fragments" : [ { "start" : 18, "end" : 170, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 375, "end" : 382, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 3.1E-187, "score" : 623.7, "model-ac" : "3tkuA01" }, { "signature" : { "accession" : "PF00069", "name" : "Pkinase", "description" : "Protein kinase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 86, "end" : 352, "hmmStart" : 2, "hmmEnd" : 264, "hmmLength" : 264, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.2E-52, "score" : 177.5, "envelopeStart" : 85, "envelopeEnd" : 352, "postProcessed" : true, "location-fragments" : [ { "start" : 86, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.7E-53, "score" : 179.2, "model-ac" : "PF00069" }, { "signature" : { "accession" : "G3DSA:3.30.60.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 990, "end" : 1059, "hmmStart" : 7, "hmmEnd" : 67, "hmmLength" : 73, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-17, "score" : 64.5, "envelopeStart" : 990, "envelopeEnd" : 1059, "postProcessed" : true, "location-fragments" : [ { "start" : 990, "end" : 1059, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-17, "score" : 65.4, "model-ac" : "3cxlA02" }, { "signature" : { "accession" : "cd00029", "name" : "C1", "description" : "C1", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 996, "end" : 1045, "sites" : [ { "description" : "putative DAG/PE binding site", "numLocations" : 10, "siteLocations" : [ { "start" : 1016, "end" : 1016, "residue" : "M" }, { "start" : 1022, "end" : 1022, "residue" : "Q" }, { "start" : 1018, "end" : 1018, "residue" : "G" }, { "start" : 1020, "end" : 1020, "residue" : "T" }, { "start" : 1006, "end" : 1006, "residue" : "P" }, { "start" : 1007, "end" : 1007, "residue" : "T" }, { "start" : 1019, "end" : 1019, "residue" : "L" }, { "start" : 1017, "end" : 1017, "residue" : "I" }, { "start" : 1003, "end" : 1003, "residue" : "F" }, { "start" : 1021, "end" : 1021, "residue" : "R" } ] }, { "description" : "zinc binding sites", "numLocations" : 8, "siteLocations" : [ { "start" : 996, "end" : 996, "residue" : "H" }, { "start" : 1009, "end" : 1009, "residue" : "C" }, { "start" : 1012, "end" : 1012, "residue" : "C" }, { "start" : 1034, "end" : 1034, "residue" : "H" }, { "start" : 1026, "end" : 1026, "residue" : "C" }, { "start" : 1029, "end" : 1029, "residue" : "C" }, { "start" : 1037, "end" : 1037, "residue" : "C" }, { "start" : 1045, "end" : 1045, "residue" : "C" } ] }, { "description" : "putative RAS interaction site", "numLocations" : 2, "siteLocations" : [ { "start" : 1008, "end" : 1008, "residue" : "K" }, { "start" : 1006, "end" : 1006, "residue" : "P" } ] } ], "evalue" : 2.46667E-16, "score" : 72.5247, "location-fragments" : [ { "start" : 996, "end" : 1045, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00029" }, { "signature" : { "accession" : "PS50108", "name" : "CRIB", "description" : "CRIB domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000095", "name" : "CRIB_dom", "description" : "CRIB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1543, "end" : 1556, "score" : 8.837, "alignment" : "ISAPSNFNHISHMG", "location-fragments" : [ { "start" : 1543, "end" : 1556, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50108" }, { "signature" : { "accession" : "PF00780", "name" : "CNH", "description" : "CNH domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001180", "name" : "CNH_dom", "description" : "Citron homology (CNH) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1216, "end" : 1478, "hmmStart" : 5, "hmmEnd" : 277, "hmmLength" : 279, "hmmBounds" : "INCOMPLETE", "evalue" : 8.0E-62, "score" : 209.3, "envelopeStart" : 1213, "envelopeEnd" : 1480, "postProcessed" : true, "location-fragments" : [ { "start" : 1216, "end" : 1478, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-62, "score" : 210.3, "model-ac" : "PF00780" }, { "signature" : { "accession" : "PS51285", "name" : "AGC_KINASE_CTER", "description" : "AGC-kinase C-terminal domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000961", "name" : "AGC-kinase_C", "description" : "AGC-kinase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein serine/threonine kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004674" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 353, "end" : 424, "score" : 12.7, "alignment" : "LGIDWSSL--RDSTAPYLPEVSSPTDTSNFdvDDMDIRTSDSVPPTASNPAFTGLHLPFVGFTFTQGSRVGDLG", "location-fragments" : [ { "start" : 353, "end" : 424, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51285" }, { "signature" : { "accession" : "SM00133", "name" : "pkinase_C_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000961", "name" : "AGC-kinase_C", "description" : "AGC-kinase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein serine/threonine kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004674" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 353, "end" : 416, "hmmStart" : 1, "hmmEnd" : 79, "hmmLength" : 79, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-7, "score" : 40.6, "location-fragments" : [ { "start" : 353, "end" : 416, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-7, "score" : 40.6, "model-ac" : "SM00133" }, { "signature" : { "accession" : "SM00233", "name" : "PH_update", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001849", "name" : "PH_domain", "description" : "Pleckstrin homology domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1066, "end" : 1186, "hmmStart" : 1, "hmmEnd" : 82, "hmmLength" : 82, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-6, "score" : 37.1, "location-fragments" : [ { "start" : 1066, "end" : 1186, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-6, "score" : 37.1, "model-ac" : "SM00233" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1584, "end" : 1612, "location-fragments" : [ { "start" : 1584, "end" : 1612, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd01243", "name" : "PH_MRCK", "description" : "PH_MRCK", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1055, "end" : 1189, "sites" : [ ], "evalue" : 3.7996E-83, "score" : 266.47, "location-fragments" : [ { "start" : 1055, "end" : 1189, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01243" }, { "signature" : { "accession" : "SM00285", "name" : "PBD_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000095", "name" : "CRIB_dom", "description" : "CRIB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1543, "end" : 1580, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 4.6E-7, "score" : 39.5, "location-fragments" : [ { "start" : 1543, "end" : 1580, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-7, "score" : 39.5, "model-ac" : "SM00285" }, { "signature" : { "accession" : "PS00479", "name" : "ZF_DAG_PE_1", "description" : "Zinc finger phorbol-ester/DAG-type signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 996, "end" : 1045, "level" : "STRONG", "cigarAlignment" : "1M1I1M10I1M2I1M3I1M9I1M2I1M4I1M2I1M7I1M", "alignment" : "HqFlirtfsaptkCnhCtslMigltrqgvvCevCgfacHttCcdkvpiaC", "location-fragments" : [ { "start" : 996, "end" : 1045, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00479" }, { "signature" : { "accession" : "PF00433", "name" : "Pkinase_C", "description" : "Protein kinase C terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR017892", "name" : "Pkinase_C", "description" : "Protein kinase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein serine/threonine kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004674" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 371, "end" : 414, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 7.1E-5, "score" : 23.4, "envelopeStart" : 371, "envelopeEnd" : 414, "postProcessed" : true, "location-fragments" : [ { "start" : 371, "end" : 414, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-5, "score" : 24.7, "model-ac" : "PF00433" }, { "signature" : { "accession" : "SM00220", "name" : "serkin_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 85, "end" : 352, "hmmStart" : 1, "hmmEnd" : 231, "hmmLength" : 231, "hmmBounds" : "COMPLETE", "evalue" : 3.2E-81, "score" : 285.8, "location-fragments" : [ { "start" : 85, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-81, "score" : 285.8, "model-ac" : "SM00220" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 865, "end" : 906, "location-fragments" : [ { "start" : 865, "end" : 906, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PS00107", "name" : "PROTEIN_KINASE_ATP", "description" : "Protein kinases ATP-binding region signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017441", "name" : "Protein_kinase_ATP_BS", "description" : "Protein kinase, ATP binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 91, "end" : 114, "level" : "STRONG", "cigarAlignment" : "10M1I1M8I4M", "alignment" : "IGRGAFGEVFvVrmkgsekvFAMK", "location-fragments" : [ { "start" : 91, "end" : 114, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00107" }, { "signature" : { "accession" : "PF15796", "name" : "KELK", "description" : "KELK-motif containing domain of MRCK Ser/Thr protein kinase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR031597", "name" : "KELK", "description" : "KELK-motif containing domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Thermogenesis", "databaseName" : "KEGG", "id" : "04714+2.7.11.1" }, { "name" : "Human papillomavirus infection", "databaseName" : "KEGG", "id" : "05165+2.7.11.1" }, { "name" : "Human cytomegalovirus infection", "databaseName" : "KEGG", "id" : "05163+2.7.11.1" }, { "name" : "mTOR signaling pathway", "databaseName" : "KEGG", "id" : "04150+2.7.11.1" }, { "name" : "Relaxin signaling pathway", "databaseName" : "KEGG", "id" : "04926+2.7.11.1" }, { "name" : "Human immunodeficiency virus 1 infection", "databaseName" : "KEGG", "id" : "05170+2.7.11.1" }, { "name" : "PI3K-Akt signaling pathway", "databaseName" : "KEGG", "id" : "04151+2.7.11.1" } ] } }, "locations" : [ { "start" : 502, "end" : 581, "hmmStart" : 1, "hmmEnd" : 80, "hmmLength" : 80, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-28, "score" : 98.3, "envelopeStart" : 502, "envelopeEnd" : 581, "postProcessed" : true, "location-fragments" : [ { "start" : 502, "end" : 581, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-28, "score" : 98.3, "model-ac" : "PF15796" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 503, "end" : 642, "location-fragments" : [ { "start" : 503, "end" : 642, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1636, "end" : 1672, "location-fragments" : [ { "start" : 1636, "end" : 1672, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50081", "name" : "ZF_DAG_PE_2", "description" : "Zinc finger phorbol-ester/DAG-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 995, "end" : 1045, "score" : 14.189, "alignment" : "SHQFLIRTFSAPTKCNHCTSLMIGLTRQGVVCEVCGFACHTTCCDKVPIAC", "location-fragments" : [ { "start" : 995, "end" : 1045, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50081" }, { "signature" : { "accession" : "PS00108", "name" : "PROTEIN_KINASE_ST", "description" : "Serine/Threonine protein kinases active-site signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR008271", "name" : "Ser/Thr_kinase_AS", "description" : "Serine/threonine-protein kinase, active site", "type" : "ACTIVE_SITE", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 205, "end" : 217, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I3M2I4M", "alignment" : "YvHrDIKpdNVLL", "location-fragments" : [ { "start" : 205, "end" : 217, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00108" }, { "signature" : { "accession" : "PR00008", "name" : "DAGPEDOMAIN", "description" : "Diacylglycerol/phorbol-ester binding signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR020454", "name" : "DAG/PE-bd", "description" : "Diacylglycerol/phorbol-ester binding", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1034, "end" : 1046, "pvalue" : 0.0136, "score" : 36.1, "motifNumber" : 4, "location-fragments" : [ { "start" : 1034, "end" : 1046, "dc-status" : "CONTINUOUS" } ] }, { "start" : 993, "end" : 1007, "pvalue" : 1.04E-4, "score" : 35.31, "motifNumber" : 1, "location-fragments" : [ { "start" : 993, "end" : 1007, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1009, "end" : 1018, "pvalue" : 0.00734, "score" : 40.99, "motifNumber" : 2, "location-fragments" : [ { "start" : 1009, "end" : 1018, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1022, "end" : 1033, "pvalue" : 0.00189, "score" : 43.23, "motifNumber" : 3, "location-fragments" : [ { "start" : 1022, "end" : 1033, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-5, "graphscan" : "IIII", "model-ac" : "PR00008" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 655, "end" : 725, "location-fragments" : [ { "start" : 655, "end" : 725, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PS50219", "name" : "CNH", "description" : "Citron homology (CNH) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001180", "name" : "CNH_dom", "description" : "Citron homology (CNH) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1207, "end" : 1483, "score" : 23.8, "alignment" : "LRAVMSGAIVDPDRLVIGTEDGLFCL----DLD---HSEMARVGEGKKVFEMEYIEKEQLLLVLSgkQRHVRLIPVRALDG-DEVEWIKVTESKGCITFAVGQLSRNVhCLCVAIKRQNTSQIIIYEItRTRQRHKRMREVMIPTQVQTVQVLSEARLCVGYQSGFSIYNISgDHLAMPLIGTDNPVASflSYSNSEALKCIELPRGEFLLVFQTLGIYVDSQGRKSRDK-EIMYPAYPIAVSYSDGYLLVFSEIHVDVFNVETGDWVQTLNTKRALPLDTHGSLA", "location-fragments" : [ { "start" : 1207, "end" : 1483, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50219" }, { "signature" : { "accession" : "cd00132", "name" : "CRIB", "description" : "CRIB", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1541, "end" : 1577, "sites" : [ { "description" : "GTPase interaction site", "numLocations" : 7, "siteLocations" : [ { "start" : 1543, "end" : 1543, "residue" : "I" }, { "start" : 1551, "end" : 1551, "residue" : "H" }, { "start" : 1573, "end" : 1573, "residue" : "I" }, { "start" : 1554, "end" : 1554, "residue" : "H" }, { "start" : 1549, "end" : 1549, "residue" : "F" }, { "start" : 1569, "end" : 1569, "residue" : "L" }, { "start" : 1546, "end" : 1546, "residue" : "P" } ] } ], "evalue" : 1.69309E-8, "score" : 49.7445, "location-fragments" : [ { "start" : 1541, "end" : 1577, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00132" }, { "signature" : { "accession" : "G3DSA:2.30.29.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011993", "name" : "PH-like_dom_sf", "description" : "PH-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1067, "end" : 1184, "hmmStart" : 3, "hmmEnd" : 111, "hmmLength" : 117, "hmmBounds" : "COMPLETE", "evalue" : 5.0E-42, "score" : 144.9, "envelopeStart" : 1067, "envelopeEnd" : 1184, "postProcessed" : true, "location-fragments" : [ { "start" : 1067, "end" : 1184, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-42, "score" : 146.6, "model-ac" : "2rovA00" }, { "signature" : { "accession" : "SM00109", "name" : "c1_12", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 996, "end" : 1045, "hmmStart" : 1, "hmmEnd" : 61, "hmmLength" : 61, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-12, "score" : 57.7, "location-fragments" : [ { "start" : 996, "end" : 1045, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-12, "score" : 57.7, "model-ac" : "SM00109" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1572, "end" : 1672, "location-fragments" : [ { "start" : 1572, "end" : 1672, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR22988", "name" : "MYOTONIC DYSTROPHY S/T KINASE-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 1583, "hmmStart" : 5, "hmmEnd" : 1527, "hmmLength" : 1548, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 1660, "location-fragments" : [ { "start" : 12, "end" : 1583, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "SERINE/THREONINE-PROTEIN KINASE GENGHIS KHAN", "score" : 2155.8, "model-ac" : "PTHR22988" }, { "signature" : { "accession" : "SSF57889", "name" : "Cysteine-rich domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 985, "end" : 1049, "hmmLength" : 84, "location-fragments" : [ { "start" : 985, "end" : 1049, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.99E-17, "model-ac" : "0043160" }, { "signature" : { "accession" : "PTHR22988:SF66", "name" : "SERINE/THREONINE-PROTEIN KINASE GENGHIS KHAN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 1583, "hmmStart" : 5, "hmmEnd" : 1527, "hmmLength" : 1548, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 1660, "location-fragments" : [ { "start" : 12, "end" : 1583, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "SERINE/THREONINE-PROTEIN KINASE GENGHIS KHAN", "score" : 2155.8, "model-ac" : "PTHR22988:SF66" }, { "signature" : { "accession" : "PS50003", "name" : "PH_DOMAIN", "description" : "PH domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001849", "name" : "PH_domain", "description" : "Pleckstrin homology domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1065, "end" : 1184, "score" : 9.125, "alignment" : "GTAYEGYVKVPRAGgVKKGWVRQFVVVCDFKLFLYDISadrNALPSVQVSQVLDMRDEHFSVSSVRESDVihamkkdIPCIFRITTSLLEpselqNHTLMLADTESEKSKWVVALSELHR", "location-fragments" : [ { "start" : 1065, "end" : 1184, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50003" }, { "signature" : { "accession" : "SSF50729", "name" : "PH domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 1064, "end" : 1185, "hmmLength" : 123, "location-fragments" : [ { "start" : 1064, "end" : 1185, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.95E-9, "model-ac" : "0050619" }, { "signature" : { "accession" : "PF00130", "name" : "C1_1", "description" : "Phorbol esters/diacylglycerol binding domain (C1 domain)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 996, "end" : 1046, "hmmStart" : 1, "hmmEnd" : 51, "hmmLength" : 53, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.0E-11, "score" : 42.6, "envelopeStart" : 996, "envelopeEnd" : 1047, "postProcessed" : true, "location-fragments" : [ { "start" : 996, "end" : 1046, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-11, "score" : 43.8, "model-ac" : "PF00130" }, { "signature" : { "accession" : "PS50011", "name" : "PROTEIN_KINASE_DOM", "description" : "Protein kinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 85, "end" : 352, "score" : 44.202, "alignment" : "FEMVKVIGRGAFGEVFVVRMKGSEKVFAMKILNKWEMLRRaEIACFQEERDVLVYGDRRWITNLHYAFQDEANLYLVMDYYCGGDLLTLLSKFEDRLPEDMARFYIAEMVLAISSVHDLRYVHRDIKPDNVLLDANGHIRLADFGSCLKLSEDGTvQSNVAVGTPDYISPEILRamedGQGRYGPECDWWSLGVCMYEMLYGETPF--YaESLVETYGKIMNH----------KncfdfpsdlpveVTNDAKDLMKRLIC-SAEYRLGQNGVEDfknHAWF", "location-fragments" : [ { "start" : 85, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50011" }, { "signature" : { "accession" : "SM00036", "name" : "nik_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001180", "name" : "CNH_dom", "description" : "Citron homology (CNH) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1207, "end" : 1498, "hmmStart" : 1, "hmmEnd" : 375, "hmmLength" : 375, "hmmBounds" : "COMPLETE", "evalue" : 6.7E-21, "score" : 85.4, "location-fragments" : [ { "start" : 1207, "end" : 1498, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-21, "score" : 85.4, "model-ac" : "SM00036" } ], "xref" : [ { "name" : "XP_018910529.1 PREDICTED: serine/threonine-protein kinase Genghis Khan isoform X1 [Bemisia tabaci]", "id" : "XP_018910529.1" }, { "name" : "XP_018910537.1 PREDICTED: serine/threonine-protein kinase Genghis Khan isoform X1 [Bemisia tabaci]", "id" : "XP_018910537.1" } ] },{ "sequence" : "MFRITEILSQHGWMDLLPELERNRVNDSLLKILSEEEIKNILPLGPAQLFIKAFKHDHNLTSLDIQEANKTMTSMSETSSILRESMAEVYNLTNGDMQGCDKLSESRIEAMLRDDNDELNSNTSSHSSPLSTALPRQSSETPGSFQFSPPANPSSSRDLSRKRANKENFIPSRIFSTPDSNTVPESLNLSAGISPVNEITQPPLKVKKVVVNFASVSTENTINSSDQLPSVNKSPRKQSTPRKLDFNVANALQISQPSTSRASEIVARNVCDNGSSGVQDDLIAKNNNNVQNFSNPEISDESTGNVPVNVSSNNNIETNRNVESHVNVESHENVESHENLKSHENLESNKNVESDKTAENTNKSNSKAHIVITNGEKLREVLLKTTKGAQVLAFFEKELSLSDSDSKKVCDIIIDHVLHDQPKATITRGEWDMLSDAVVQLFPTEVKETYYVPPTSGSAGEKCSARGRLINKYEAFRKYLIRTGAMSSQRSKKAPQKVIDTNVQKALDWLKKNVEPAVLAIEYWTVTAQERLTELIVLKSIATQEYLVLYPPLKNPAIGIQLVSTDFNHLYATKANVFLNDWSPIAQKILDLLRLKRGSRWQENIALAGINIYATDPEEIKLSALLLLPYFFPTPGDVNFSRNKNLSWVPSKLECAKGFILITPTLTLLEVEIKKRQTFFQSKKLVLPPFVVLVGRVGNFEESIVVIDSIKYYFDSPISAFDWCFKAHFALYYSYSPETRAPYTFIQKYVYKINTKRDRNYIQVTSLAKQLNLSSV", "md5" : "6409253435b7ceab3d480b4931a2ae40", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 281, "end" : 323, "location-fragments" : [ { "start" : 281, "end" : 323, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 112, "end" : 177, "location-fragments" : [ { "start" : 112, "end" : 177, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR31025", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 334, "end" : 755, "hmmStart" : 21, "hmmEnd" : 426, "hmmLength" : 446, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 295, "envelopeEnd" : 766, "location-fragments" : [ { "start" : 334, "end" : 755, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-14, "familyName" : "SI:DKEY-286J15.1", "score" : 54.8, "model-ac" : "PTHR31025" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 121, "end" : 158, "location-fragments" : [ { "start" : 121, "end" : 158, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR31025:SF9", "name" : "SI:DKEY-286J15.1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 334, "end" : 755, "hmmStart" : 21, "hmmEnd" : 426, "hmmLength" : 446, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 295, "envelopeEnd" : 766, "location-fragments" : [ { "start" : 334, "end" : 755, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-14, "familyName" : "SI:DKEY-286J15.1", "score" : 54.8, "model-ac" : "PTHR31025:SF9" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 324, "end" : 362, "location-fragments" : [ { "start" : 324, "end" : 362, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 281, "end" : 367, "location-fragments" : [ { "start" : 281, "end" : 367, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910135.1 PREDICTED: uncharacterized protein LOC109039197 [Bemisia tabaci]", "id" : "XP_018910135.1" } ] },{ "sequence" : "MDYPKHIFFALSLCLCMRNGESNIYILEDAIYRNSQELSGNRYKRQTHPASTFAKFSGADDVFGPLVGHVRPPLDQGEQRSDFNGNLTPNLADSVDLTQPQGPPNGLVDYLTPPSPNVQTPAFNPTSHTLNPAPLPPPFAPPTTTPDFSNLFGSASHFSSSFQAPAPSHGPQSRDLNGIHIDQPFQPTLLNEGGKWDLGYDASEILNPPVENSAPSRHLEDSLGPPPNFRRPSSLPASNPTFAASQNAPVSFSNHNQFADYNQGHNNFPTTSPFGPPPQSPHHAPHSDIVWGVPKSNGIPQPSNPFTSGLEPPGFRQQPVNSFNSNLGPKNLGSLGAASQATFTTKAPPPFSQFDSFVPQGSVRDNGFLIPPSDFGTPPQHTKRQSESLVPPYKFFGSPGTRSFQKKRQSVDGLGGKRWAYKRRSDDEDADSEETEGGAQIHAPVFSYVKTDKNGHFKWGVRQGLPSAFTAK", "md5" : "dcf2aad73b27341019d732ca8a0d4687", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 115, "end" : 134, "location-fragments" : [ { "start" : 115, "end" : 134, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 411, "end" : 429, "location-fragments" : [ { "start" : 411, "end" : 429, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 400, "end" : 442, "location-fragments" : [ { "start" : 400, "end" : 442, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 115, "end" : 129, "location-fragments" : [ { "start" : 115, "end" : 129, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 207, "end" : 387, "location-fragments" : [ { "start" : 207, "end" : 387, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 297, "end" : 360, "location-fragments" : [ { "start" : 297, "end" : 360, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 234, "end" : 270, "location-fragments" : [ { "start" : 234, "end" : 270, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910454.1 PREDICTED: basic salivary proline-rich protein 2-like [Bemisia tabaci]", "id" : "XP_018910454.1" } ] },{ "sequence" : "MFSQLCWPSDSLLTSRMAKGKPMRKGKSAINEVVTRDYTIHMHARLAGRQGTKKRAPRAVKEIRKFAFKAMGTPDVRIDTRLNKHVWMKGIKGVPNRIRVRLSRRRNEDEDSPHKLYTLVQWVPVRTFKKLQTENVDTSQE", "md5" : "9622f18cc8d958645f72efc106d32ab6", "matches" : [ { "signature" : { "accession" : "PF01198", "name" : "Ribosomal_L31e", "description" : "Ribosomal protein L31e", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000054", "name" : "Ribosomal_L31e", "description" : "Ribosomal protein L31e", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of ribosome", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003735" }, { "name" : "translation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006412" }, { "name" : "ribosome", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005840" } ], "pathwayXRefs" : [ { "name" : "Eukaryotic Translation Termination", "databaseName" : "Reactome", "id" : "R-HSA-72764" }, { "name" : "L13a-mediated translational silencing of Ceruloplasmin expression", "databaseName" : "Reactome", "id" : "R-HSA-156827" }, { "name" : "GTP hydrolysis and joining of the 60S ribosomal subunit", "databaseName" : "Reactome", "id" : "R-HSA-72706" }, { "name" : "Major pathway of rRNA processing in the nucleolus and cytosol", "databaseName" : "Reactome", "id" : "R-HSA-6791226" }, { "name" : "Viral mRNA Translation", "databaseName" : "Reactome", "id" : "R-HSA-192823" }, { "name" : "Selenocysteine synthesis", "databaseName" : "Reactome", "id" : "R-HSA-2408557" }, { "name" : "Peptide chain elongation", "databaseName" : "Reactome", "id" : "R-HSA-156902" }, { "name" : "Regulation of expression of SLITs and ROBOs", "databaseName" : "Reactome", "id" : "R-HSA-9010553" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975957" }, { "name" : "Response of EIF2AK4 (GCN2) to amino acid deficiency", "databaseName" : "Reactome", "id" : "R-HSA-9633012" }, { "name" : "Formation of a pool of free 40S subunits", "databaseName" : "Reactome", "id" : "R-HSA-72689" }, { "name" : "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975956" } ] } }, "locations" : [ { "start" : 32, "end" : 113, "hmmStart" : 1, "hmmEnd" : 81, "hmmLength" : 82, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.7E-40, "score" : 136.0, "envelopeStart" : 32, "envelopeEnd" : 114, "postProcessed" : true, "location-fragments" : [ { "start" : 32, "end" : 113, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-40, "score" : 136.5, "model-ac" : "PF01198" }, { "signature" : { "accession" : "SM01380", "name" : "Ribosomal_L31e_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000054", "name" : "Ribosomal_L31e", "description" : "Ribosomal protein L31e", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of ribosome", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003735" }, { "name" : "translation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006412" }, { "name" : "ribosome", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005840" } ], "pathwayXRefs" : [ { "name" : "Eukaryotic Translation Termination", "databaseName" : "Reactome", "id" : "R-HSA-72764" }, { "name" : "L13a-mediated translational silencing of Ceruloplasmin expression", "databaseName" : "Reactome", "id" : "R-HSA-156827" }, { "name" : "GTP hydrolysis and joining of the 60S ribosomal subunit", "databaseName" : "Reactome", "id" : "R-HSA-72706" }, { "name" : "Major pathway of rRNA processing in the nucleolus and cytosol", "databaseName" : "Reactome", "id" : "R-HSA-6791226" }, { "name" : "Viral mRNA Translation", "databaseName" : "Reactome", "id" : "R-HSA-192823" }, { "name" : "Selenocysteine synthesis", "databaseName" : "Reactome", "id" : "R-HSA-2408557" }, { "name" : "Peptide chain elongation", "databaseName" : "Reactome", "id" : "R-HSA-156902" }, { "name" : "Regulation of expression of SLITs and ROBOs", "databaseName" : "Reactome", "id" : "R-HSA-9010553" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975957" }, { "name" : "Response of EIF2AK4 (GCN2) to amino acid deficiency", "databaseName" : "Reactome", "id" : "R-HSA-9633012" }, { "name" : "Formation of a pool of free 40S subunits", "databaseName" : "Reactome", "id" : "R-HSA-72689" }, { "name" : "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975956" } ] } }, "locations" : [ { "start" : 31, "end" : 115, "hmmStart" : 1, "hmmEnd" : 91, "hmmLength" : 91, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-46, "score" : 170.1, "location-fragments" : [ { "start" : 31, "end" : 115, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-46, "score" : 170.1, "model-ac" : "SM01380" }, { "signature" : { "accession" : "PS01144", "name" : "RIBOSOMAL_L31E", "description" : "Ribosomal protein L31e signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR020052", "name" : "Ribosomal_L31e_CS", "description" : "Ribosomal protein L31e, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "translation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006412" }, { "name" : "structural constituent of ribosome", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003735" }, { "name" : "ribosome", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005840" } ], "pathwayXRefs" : [ { "name" : "GTP hydrolysis and joining of the 60S ribosomal subunit", "databaseName" : "Reactome", "id" : "R-HSA-72706" }, { "name" : "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975956" }, { "name" : "Response of EIF2AK4 (GCN2) to amino acid deficiency", "databaseName" : "Reactome", "id" : "R-HSA-9633012" }, { "name" : "Regulation of expression of SLITs and ROBOs", "databaseName" : "Reactome", "id" : "R-HSA-9010553" }, { "name" : "Selenocysteine synthesis", "databaseName" : "Reactome", "id" : "R-HSA-2408557" }, { "name" : "Formation of a pool of free 40S subunits", "databaseName" : "Reactome", "id" : "R-HSA-72689" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975957" }, { "name" : "Eukaryotic Translation Termination", "databaseName" : "Reactome", "id" : "R-HSA-72764" }, { "name" : "Viral mRNA Translation", "databaseName" : "Reactome", "id" : "R-HSA-192823" }, { "name" : "Major pathway of rRNA processing in the nucleolus and cytosol", "databaseName" : "Reactome", "id" : "R-HSA-6791226" }, { "name" : "Peptide chain elongation", "databaseName" : "Reactome", "id" : "R-HSA-156902" }, { "name" : "L13a-mediated translational silencing of Ceruloplasmin expression", "databaseName" : "Reactome", "id" : "R-HSA-156827" } ] } }, "locations" : [ { "start" : 76, "end" : 90, "level" : "STRONG", "cigarAlignment" : "4M2I2M1I1M1I1M1I2M", "alignment" : "VRIDtrLNkHvWmKG", "location-fragments" : [ { "start" : 76, "end" : 90, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01144" }, { "signature" : { "accession" : "cd00463", "name" : "Ribosomal_L31e", "description" : "Ribosomal_L31e", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000054", "name" : "Ribosomal_L31e", "description" : "Ribosomal protein L31e", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of ribosome", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003735" }, { "name" : "translation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006412" }, { "name" : "ribosome", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005840" } ], "pathwayXRefs" : [ { "name" : "Eukaryotic Translation Termination", "databaseName" : "Reactome", "id" : "R-HSA-72764" }, { "name" : "L13a-mediated translational silencing of Ceruloplasmin expression", "databaseName" : "Reactome", "id" : "R-HSA-156827" }, { "name" : "GTP hydrolysis and joining of the 60S ribosomal subunit", "databaseName" : "Reactome", "id" : "R-HSA-72706" }, { "name" : "Major pathway of rRNA processing in the nucleolus and cytosol", "databaseName" : "Reactome", "id" : "R-HSA-6791226" }, { "name" : "Viral mRNA Translation", "databaseName" : "Reactome", "id" : "R-HSA-192823" }, { "name" : "Selenocysteine synthesis", "databaseName" : "Reactome", "id" : "R-HSA-2408557" }, { "name" : "Peptide chain elongation", "databaseName" : "Reactome", "id" : "R-HSA-156902" }, { "name" : "Regulation of expression of SLITs and ROBOs", "databaseName" : "Reactome", "id" : "R-HSA-9010553" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975957" }, { "name" : "Response of EIF2AK4 (GCN2) to amino acid deficiency", "databaseName" : "Reactome", "id" : "R-HSA-9633012" }, { "name" : "Formation of a pool of free 40S subunits", "databaseName" : "Reactome", "id" : "R-HSA-72689" }, { "name" : "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975956" } ] } }, "locations" : [ { "start" : 30, "end" : 114, "sites" : [ { "description" : "23S rRNA binding site", "numLocations" : 27, "siteLocations" : [ { "start" : 64, "end" : 64, "residue" : "R" }, { "start" : 86, "end" : 86, "residue" : "V" }, { "start" : 76, "end" : 76, "residue" : "V" }, { "start" : 96, "end" : 96, "residue" : "N" }, { "start" : 61, "end" : 61, "residue" : "K" }, { "start" : 88, "end" : 88, "residue" : "M" }, { "start" : 97, "end" : 97, "residue" : "R" }, { "start" : 57, "end" : 57, "residue" : "P" }, { "start" : 92, "end" : 92, "residue" : "K" }, { "start" : 56, "end" : 56, "residue" : "A" }, { "start" : 87, "end" : 87, "residue" : "W" }, { "start" : 53, "end" : 53, "residue" : "K" }, { "start" : 79, "end" : 79, "residue" : "D" }, { "start" : 84, "end" : 84, "residue" : "K" }, { "start" : 77, "end" : 77, "residue" : "R" }, { "start" : 78, "end" : 78, "residue" : "I" }, { "start" : 41, "end" : 41, "residue" : "H" }, { "start" : 60, "end" : 60, "residue" : "V" }, { "start" : 70, "end" : 70, "residue" : "A" }, { "start" : 54, "end" : 54, "residue" : "K" }, { "start" : 91, "end" : 91, "residue" : "I" }, { "start" : 50, "end" : 50, "residue" : "Q" }, { "start" : 58, "end" : 58, "residue" : "R" }, { "start" : 83, "end" : 83, "residue" : "N" }, { "start" : 90, "end" : 90, "residue" : "G" }, { "start" : 69, "end" : 69, "residue" : "K" }, { "start" : 89, "end" : 89, "residue" : "K" } ] } ], "evalue" : 4.89845E-27, "score" : 94.1732, "location-fragments" : [ { "start" : 30, "end" : 114, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00463" }, { "signature" : { "accession" : "SSF54575", "name" : "Ribosomal protein L31e", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR023621", "name" : "Ribosomal_L31e_dom_sf", "description" : "Ribosomal protein L31e domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "L13a-mediated translational silencing of Ceruloplasmin expression", "databaseName" : "Reactome", "id" : "R-HSA-156827" }, { "name" : "GTP hydrolysis and joining of the 60S ribosomal subunit", "databaseName" : "Reactome", "id" : "R-HSA-72706" }, { "name" : "Major pathway of rRNA processing in the nucleolus and cytosol", "databaseName" : "Reactome", "id" : "R-HSA-6791226" }, { "name" : "Viral mRNA Translation", "databaseName" : "Reactome", "id" : "R-HSA-192823" }, { "name" : "Selenocysteine synthesis", "databaseName" : "Reactome", "id" : "R-HSA-2408557" }, { "name" : "Peptide chain elongation", "databaseName" : "Reactome", "id" : "R-HSA-156902" }, { "name" : "Regulation of expression of SLITs and ROBOs", "databaseName" : "Reactome", "id" : "R-HSA-9010553" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "Response of EIF2AK4 (GCN2) to amino acid deficiency", "databaseName" : "Reactome", "id" : "R-HSA-9633012" }, { "name" : "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975957" }, { "name" : "Formation of a pool of free 40S subunits", "databaseName" : "Reactome", "id" : "R-HSA-72689" }, { "name" : "Eukaryotic Translation Termination", "databaseName" : "Reactome", "id" : "R-HSA-72764" }, { "name" : "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975956" } ] } }, "locations" : [ { "start" : 32, "end" : 115, "hmmLength" : 85, "location-fragments" : [ { "start" : 32, "end" : 115, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-31, "model-ac" : "0037549" }, { "signature" : { "accession" : "PTHR10956", "name" : "60S RIBOSOMAL PROTEIN L31", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR000054", "name" : "Ribosomal_L31e", "description" : "Ribosomal protein L31e", "type" : "FAMILY", "goXRefs" : [ { "name" : "structural constituent of ribosome", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003735" }, { "name" : "translation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006412" }, { "name" : "ribosome", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005840" } ], "pathwayXRefs" : [ { "name" : "Eukaryotic Translation Termination", "databaseName" : "Reactome", "id" : "R-HSA-72764" }, { "name" : "L13a-mediated translational silencing of Ceruloplasmin expression", "databaseName" : "Reactome", "id" : "R-HSA-156827" }, { "name" : "GTP hydrolysis and joining of the 60S ribosomal subunit", "databaseName" : "Reactome", "id" : "R-HSA-72706" }, { "name" : "Major pathway of rRNA processing in the nucleolus and cytosol", "databaseName" : "Reactome", "id" : "R-HSA-6791226" }, { "name" : "Viral mRNA Translation", "databaseName" : "Reactome", "id" : "R-HSA-192823" }, { "name" : "Selenocysteine synthesis", "databaseName" : "Reactome", "id" : "R-HSA-2408557" }, { "name" : "Peptide chain elongation", "databaseName" : "Reactome", "id" : "R-HSA-156902" }, { "name" : "Regulation of expression of SLITs and ROBOs", "databaseName" : "Reactome", "id" : "R-HSA-9010553" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975957" }, { "name" : "Response of EIF2AK4 (GCN2) to amino acid deficiency", "databaseName" : "Reactome", "id" : "R-HSA-9633012" }, { "name" : "Formation of a pool of free 40S subunits", "databaseName" : "Reactome", "id" : "R-HSA-72689" }, { "name" : "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975956" } ] } }, "locations" : [ { "start" : 19, "end" : 133, "hmmStart" : 6, "hmmEnd" : 119, "hmmLength" : 159, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 140, "location-fragments" : [ { "start" : 19, "end" : 133, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-56, "familyName" : "", "score" : 193.2, "model-ac" : "PTHR10956" }, { "signature" : { "accession" : "PTHR10956:SF32", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 133, "hmmStart" : 6, "hmmEnd" : 119, "hmmLength" : 159, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 140, "location-fragments" : [ { "start" : 19, "end" : 133, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-56, "familyName" : "", "score" : 193.2, "model-ac" : "PTHR10956:SF32" }, { "signature" : { "accession" : "G3DSA:3.10.440.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR023621", "name" : "Ribosomal_L31e_dom_sf", "description" : "Ribosomal protein L31e domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "L13a-mediated translational silencing of Ceruloplasmin expression", "databaseName" : "Reactome", "id" : "R-HSA-156827" }, { "name" : "GTP hydrolysis and joining of the 60S ribosomal subunit", "databaseName" : "Reactome", "id" : "R-HSA-72706" }, { "name" : "Major pathway of rRNA processing in the nucleolus and cytosol", "databaseName" : "Reactome", "id" : "R-HSA-6791226" }, { "name" : "Viral mRNA Translation", "databaseName" : "Reactome", "id" : "R-HSA-192823" }, { "name" : "Selenocysteine synthesis", "databaseName" : "Reactome", "id" : "R-HSA-2408557" }, { "name" : "Peptide chain elongation", "databaseName" : "Reactome", "id" : "R-HSA-156902" }, { "name" : "Regulation of expression of SLITs and ROBOs", "databaseName" : "Reactome", "id" : "R-HSA-9010553" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "Response of EIF2AK4 (GCN2) to amino acid deficiency", "databaseName" : "Reactome", "id" : "R-HSA-9633012" }, { "name" : "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975957" }, { "name" : "Formation of a pool of free 40S subunits", "databaseName" : "Reactome", "id" : "R-HSA-72689" }, { "name" : "Eukaryotic Translation Termination", "databaseName" : "Reactome", "id" : "R-HSA-72764" }, { "name" : "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975956" } ] } }, "locations" : [ { "start" : 17, "end" : 138, "hmmStart" : 7, "hmmEnd" : 115, "hmmLength" : 120, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-50, "score" : 171.7, "envelopeStart" : 17, "envelopeEnd" : 138, "postProcessed" : true, "location-fragments" : [ { "start" : 17, "end" : 138, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-50, "score" : 172.0, "model-ac" : "1vx7700" } ], "xref" : [ { "name" : "XP_018910173.1 PREDICTED: 60S ribosomal protein L31 [Bemisia tabaci]", "id" : "XP_018910173.1" } ] },{ "sequence" : "MTGRIEGETNLRKLDQPRGMKLSIFKRAIPWILIACVLSSLRDCSASSRALSRSNVSDGRVVYSLLAPSKATPEFAGLQTLQARCMEMLTAGLNANRAMTNTMDQYGRIMGAAMGAALSRSASARAASRRGRQSRTTFDQWTYYIRPPGGGRPIRRSVTSRSSSRSGSRSSRSSPSRSSKRSVSGRSVSKKKGGSSSSSSRSKKKKRSSSSKSRSRSSEQRARKQRPIFPLRNQNLDFGPNPNFLQRKKREEDDDDDYDDDDEEEERRRELLRRAEMERQRQAALFNQNRPNQPDFDRDRFEREQALLRNRPRQEEAVPQELLDLIQPAFRQEPRREFTRFEQRSPERRRIQVPVTRTNGEPLQGLQDPPGQLLRKPPRMMTASGNPEDLARSMLDF", "md5" : "264051e1824d6fabd84b79a341154f20", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 197, "end" : 211, "location-fragments" : [ { "start" : 197, "end" : 211, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 354, "end" : 397, "location-fragments" : [ { "start" : 354, "end" : 397, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 212, "end" : 226, "location-fragments" : [ { "start" : 212, "end" : 226, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 156, "end" : 196, "location-fragments" : [ { "start" : 156, "end" : 196, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 138, "end" : 271, "location-fragments" : [ { "start" : 138, "end" : 271, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910314.1 PREDICTED: RNA polymerase-associated protein LEO1-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910314.1" } ] },{ "sequence" : "MDQEDCPRLAFVHNSIKSAPPTTGKGKVVLNVVRKITQPNATSALIQPKKTTITNKRNRDEDSTAAQKKWPPEHILELIIAYKGHPCLYDLKHPQYSNNGKRMMTLAEIRQLMDIFRPGMTEEDILRQLNSVRTQF", "md5" : "0a01a72367b71c6abc87af9e0dc13097", "matches" : [ { "signature" : { "accession" : "PS51029", "name" : "MADF", "description" : "MADF domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR006578", "name" : "MADF-dom", "description" : "MADF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 77, "end" : 136, "score" : 9.698, "alignment" : "ELIIAYKGHPCLYDLKHPQYSNNGKRMMTLAEIRQLMdifrpGMTEEDILRQLNSVRTQF--------------------------------", "location-fragments" : [ { "start" : 77, "end" : 136, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51029" }, { "signature" : { "accession" : "PTHR21505:SF5", "name" : "RE30687P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 66, "end" : 136, "hmmStart" : 7, "hmmEnd" : 72, "hmmLength" : 289, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 34, "envelopeEnd" : 136, "location-fragments" : [ { "start" : 66, "end" : 136, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-14, "familyName" : "RE30687P", "score" : 55.5, "model-ac" : "PTHR21505:SF5" }, { "signature" : { "accession" : "PTHR21505", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 66, "end" : 136, "hmmStart" : 7, "hmmEnd" : 72, "hmmLength" : 289, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 34, "envelopeEnd" : 136, "location-fragments" : [ { "start" : 66, "end" : 136, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-14, "familyName" : "RE30687P", "score" : 55.5, "model-ac" : "PTHR21505" }, { "signature" : { "accession" : "PF10545", "name" : "MADF_DNA_bdg", "description" : "Alcohol dehydrogenase transcription factor Myb/SANT-like", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006578", "name" : "MADF-dom", "description" : "MADF domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 78, "end" : 136, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 85, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.3E-8, "score" : 35.1, "envelopeStart" : 78, "envelopeEnd" : 136, "postProcessed" : true, "location-fragments" : [ { "start" : 78, "end" : 136, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.7E-9, "score" : 36.8, "model-ac" : "PF10545" } ], "xref" : [ { "name" : "XP_018909959.1 PREDICTED: uncharacterized protein LOC109039079 [Bemisia tabaci]", "id" : "XP_018909959.1" } ] },{ "sequence" : "MANLNPAETNNNCPQNSGSPGSTPDVAKKTANESANDQVMLINMGGENHLQQFSKQAGWTPKPEVDAPEVGSPEISRRVPVAKITTPETGNEVSVTRGRVSQMKSIFSGIEGNTTETKNTVSEFKNALSRTGNATSVPITRIDTKPGSEVAEKRSKTESRTDPASEGDNGSKKVFVSESETGSEQDTRSDTKSKSETGSGVEIRDGDRTEIGSRTEFESRKESGSRTESGSRMESGSRMESGSRTESGGRTESGSRTDVEVRMRIPSWKNGGLECRKSESDDSKRSSGSGKSLSTNELVSLLSERPEVVEKFILEVADADNIQRLLAQRNRSSSGESEAQVGVLDDLPTRSKRTTSVTSDLFNNWLASSPIKRAKSPSGSRSSGDWRRHLGSLDEGELFMELIKDVSNELDLDVLCHKILVNVSLLTHADRGSLFLARGLPDNRYLIAKLFDVTVNTKLEEAVEKAKAEEIRIPFGVGVAGSAALCKQVVNISHAYEDPRFNPEIDQRTGYKTSLLLCVPICNYEGDVIGVAQIINKTDGSDAFTERDIEVFQRYLTFCGIGIQNAQLFEMSVQEFRRNQILLNLARNIFTEQNNLECLVTKIMTEARELLKCERCAVFLLDSECGEAGHLERILERPGKAIEAHKPLMRRESNNVDIADVLSFKFDFKSIHFTKLFEMRDGSHMSEESNPQHQPHRKLNQIAKYVAATGQILNIGDVQSWFGVTDGNPDSQEESEEEQEIKCILCMPILNGQKTVIGVAQLINKETGQPFTDCDVSIFEAFAIFCGLGIHNTQMYESACKLMAKQKVALECLSYHATASLDDTLRLINDEIPSVETYNLYSFKFIDFDLTDDDTCRATIRMFLQCNLVQQFHIPYEVLCRWVLSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTTSTMEHHHFDQCVMILNSDGNNIFQALSTEDYRTVMKIVENSILSTDLAMYFKKKSLFMELVENGEFDWQSESKKEILCGILMTACDVGAIAKPWEVQHKMAKLVADEFFDQGDLEKLQLNQQPMAMMDRERKDELPKMQVGFIDLICLPLYKVLSETFPWIQPLYEGTMENRRHWQDLAEKVEMGLTWIDHDVIEKPVEEFSYR", "md5" : "39e5b975db7a38ca353cc2e09cb0ca8e", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 53, "end" : 76, "location-fragments" : [ { "start" : 53, "end" : 76, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF01590", "name" : "GAF", "description" : "GAF domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR003018", "name" : "GAF", "description" : "GAF domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 411, "end" : 561, "hmmStart" : 1, "hmmEnd" : 131, "hmmLength" : 133, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.5E-15, "score" : 56.5, "envelopeStart" : 411, "envelopeEnd" : 563, "postProcessed" : true, "location-fragments" : [ { "start" : 411, "end" : 561, "dc-status" : "CONTINUOUS" } ] }, { "start" : 595, "end" : 788, "hmmStart" : 1, "hmmEnd" : 131, "hmmLength" : 133, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.4E-15, "score" : 56.9, "envelopeStart" : 595, "envelopeEnd" : 790, "postProcessed" : true, "location-fragments" : [ { "start" : 595, "end" : 788, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-33, "score" : 116.0, "model-ac" : "PF01590" }, { "signature" : { "accession" : "G3DSA:3.30.450.40", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029016", "name" : "GAF-like_dom_sf", "description" : "GAF-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 392, "end" : 571, "hmmStart" : 3, "hmmEnd" : 175, "hmmLength" : 180, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-50, "score" : 173.4, "envelopeStart" : 392, "envelopeEnd" : 571, "postProcessed" : true, "location-fragments" : [ { "start" : 392, "end" : 571, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-102, "score" : 340.6, "model-ac" : "3dbaA00" }, { "signature" : { "accession" : "SM00065", "name" : "gaf_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003018", "name" : "GAF", "description" : "GAF domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 411, "end" : 573, "hmmStart" : 1, "hmmEnd" : 142, "hmmLength" : 142, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-22, "score" : 91.1, "location-fragments" : [ { "start" : 411, "end" : 573, "dc-status" : "CONTINUOUS" } ] }, { "start" : 595, "end" : 800, "hmmStart" : 1, "hmmEnd" : 142, "hmmLength" : 142, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-17, "score" : 74.2, "location-fragments" : [ { "start" : 595, "end" : 800, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.1E-45, "score" : 165.3, "model-ac" : "SM00065" }, { "signature" : { "accession" : "PTHR11347:SF193", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 350, "end" : 1163, "hmmStart" : 32, "hmmEnd" : 823, "hmmLength" : 884, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 315, "envelopeEnd" : 1165, "location-fragments" : [ { "start" : 350, "end" : 1163, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "", "score" : 1348.3, "model-ac" : "PTHR11347:SF193" }, { "signature" : { "accession" : "PS00126", "name" : "PDEASE_I_1", "description" : "3'5'-cyclic nucleotide phosphodiesterase domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR023174", "name" : "PDEase_CS", "description" : "3'5'-cyclic nucleotide phosphodiesterase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "phosphoric diester hydrolase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008081" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 936, "end" : 947, "level" : "STRONG", "cigarAlignment" : "3M1I1M1I1M2I1M1I1M", "alignment" : "HDLdHrGtnNaF", "location-fragments" : [ { "start" : 936, "end" : 947, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00126" }, { "signature" : { "accession" : "SSF55781", "name" : "GAF domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 576, "end" : 817, "hmmLength" : 187, "location-fragments" : [ { "start" : 576, "end" : 630, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 684, "end" : 817, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 3.27E-35, "model-ac" : "0048135" }, { "signature" : { "accession" : "SM00471", "name" : "hd_13", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR003607", "name" : "HD/PDEase_dom", "description" : "HD/PDEase domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 893, "end" : 1060, "hmmStart" : 1, "hmmEnd" : 59, "hmmLength" : 59, "hmmBounds" : "COMPLETE", "evalue" : 5.4E-5, "score" : 32.6, "location-fragments" : [ { "start" : 893, "end" : 1060, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-5, "score" : 32.6, "model-ac" : "SM00471" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 183, "end" : 228, "location-fragments" : [ { "start" : 183, "end" : 228, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PR00387", "name" : "PDIESTERASE1", "description" : "3'5'-cyclic nucleotide phosphodiesterase signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR023088", "name" : "PDEase", "description" : "3'5'-cyclic nucleotide phosphodiesterase", "type" : "FAMILY", "goXRefs" : [ { "name" : "phosphoric diester hydrolase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008081" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 922, "end" : 935, "pvalue" : 8.55E-7, "score" : 48.71, "motifNumber" : 2, "location-fragments" : [ { "start" : 922, "end" : 935, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1043, "end" : 1056, "pvalue" : 3.19E-6, "score" : 48.29, "motifNumber" : 5, "location-fragments" : [ { "start" : 1043, "end" : 1056, "dc-status" : "CONTINUOUS" } ] }, { "start" : 936, "end" : 951, "pvalue" : 1.37E-7, "score" : 57.0, "motifNumber" : 3, "location-fragments" : [ { "start" : 936, "end" : 951, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1060, "end" : 1076, "pvalue" : 2.16E-7, "score" : 54.12, "motifNumber" : 6, "location-fragments" : [ { "start" : 1060, "end" : 1076, "dc-status" : "CONTINUOUS" } ] }, { "start" : 891, "end" : 904, "pvalue" : 7.63E-6, "score" : 54.57, "motifNumber" : 1, "location-fragments" : [ { "start" : 891, "end" : 904, "dc-status" : "CONTINUOUS" } ] }, { "start" : 962, "end" : 978, "pvalue" : 3.17E-5, "score" : 38.12, "motifNumber" : 4, "location-fragments" : [ { "start" : 962, "end" : 978, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-29, "graphscan" : "IIIIII", "model-ac" : "PR00387" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 111, "end" : 291, "location-fragments" : [ { "start" : 111, "end" : 291, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 229, "end" : 250, "location-fragments" : [ { "start" : 229, "end" : 250, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF55781", "name" : "GAF domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 394, "end" : 590, "hmmLength" : 187, "location-fragments" : [ { "start" : 394, "end" : 590, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.33E-39, "model-ac" : "0048135" }, { "signature" : { "accession" : "cd00077", "name" : "HDc", "description" : "HDc", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR003607", "name" : "HD/PDEase_dom", "description" : "HD/PDEase domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 895, "end" : 1070, "sites" : [ { "description" : "Mg2+ binding site", "numLocations" : 1, "siteLocations" : [ { "start" : 937, "end" : 937, "residue" : "D" } ] }, { "description" : "Zn2+ binding site", "numLocations" : 4, "siteLocations" : [ { "start" : 900, "end" : 900, "residue" : "H" }, { "start" : 937, "end" : 937, "residue" : "D" }, { "start" : 1047, "end" : 1047, "residue" : "D" }, { "start" : 936, "end" : 936, "residue" : "H" } ] } ], "evalue" : 3.94032E-12, "score" : 63.1273, "location-fragments" : [ { "start" : 895, "end" : 1070, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00077" }, { "signature" : { "accession" : "PS51845", "name" : "PDEASE_I_2", "description" : "3'5'-cyclic nucleotide phosphodiesterase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002073", "name" : "PDEase_catalytic_dom", "description" : "3'5'-cyclic nucleotide phosphodiesterase, catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" }, { "name" : "3',5'-cyclic-nucleotide phosphodiesterase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004114" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 820, "end" : 1143, "score" : 146.539, "alignment" : "SLDDTLRLINDEIPSVETYNLYSFKFIDFDLTDDDTCRATIRMFLQCNLVQQFHIPYEVLCRWVLSVKKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-TTSTMEHHHFDQCVMILNSDGNNIFQALSTEDYRTVMKIVENSILSTDLAMYFKKKSLFMELVENGEFDWQSESKKEILCGILMTACDVGAIAKPWEVQHKMAKLVADEFFDQGDLEKLQlNQQPMAMMDRERKDELPKMQVGFIDLICLPLYKVLSETFPWIQPLYEGTMENRRHWQDLAEKV", "location-fragments" : [ { "start" : 820, "end" : 1143, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51845" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 111, "end" : 142, "location-fragments" : [ { "start" : 111, "end" : 142, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00233", "name" : "PDEase_I", "description" : "3'5'-cyclic nucleotide phosphodiesterase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002073", "name" : "PDEase_catalytic_dom", "description" : "3'5'-cyclic nucleotide phosphodiesterase, catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" }, { "name" : "3',5'-cyclic-nucleotide phosphodiesterase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004114" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 895, "end" : 1127, "hmmStart" : 1, "hmmEnd" : 235, "hmmLength" : 238, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.3E-82, "score" : 275.8, "envelopeStart" : 895, "envelopeEnd" : 1129, "postProcessed" : true, "location-fragments" : [ { "start" : 895, "end" : 1127, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-82, "score" : 276.8, "model-ac" : "PF00233" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 38, "location-fragments" : [ { "start" : 1, "end" : 38, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.10.1300.10", "name" : "Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036971", "name" : "PDEase_catalytic_dom_sf", "description" : "3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "3',5'-cyclic-nucleotide phosphodiesterase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004114" }, { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 817, "end" : 1143, "hmmStart" : 10, "hmmEnd" : 328, "hmmLength" : 330, "hmmBounds" : "COMPLETE", "evalue" : 9.6E-118, "score" : 394.9, "envelopeStart" : 817, "envelopeEnd" : 1143, "postProcessed" : true, "location-fragments" : [ { "start" : 817, "end" : 1143, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.2E-118, "score" : 395.5, "model-ac" : "3jwqA00" }, { "signature" : { "accession" : "SSF109604", "name" : "HD-domain/PDEase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 836, "end" : 1151, "hmmLength" : 415, "location-fragments" : [ { "start" : 836, "end" : 1151, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.24E-118, "model-ac" : "0049430" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 146, "end" : 167, "location-fragments" : [ { "start" : 146, "end" : 167, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR11347", "name" : "CYCLIC NUCLEOTIDE PHOSPHODIESTERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 350, "end" : 1163, "hmmStart" : 32, "hmmEnd" : 823, "hmmLength" : 884, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 315, "envelopeEnd" : 1165, "location-fragments" : [ { "start" : 350, "end" : 1163, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "", "score" : 1348.3, "model-ac" : "PTHR11347" } ], "xref" : [ { "name" : "XP_018909887.1 PREDICTED: cGMP-specific 3',5'-cyclic phosphodiesterase-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909887.1" } ] },{ "sequence" : "MGGNWGGNGNGDGNGDNGGQPQLPPPQPSIWERRASIHAFASQDPCKARQVRTNQLTRGIANQACTAAYVDFMALTVSERESCPEAEAPECRALPNHHNWRCTFSCNVSRHSGNSTPSPRVARHQSTLARLFSCASGSSTSRRRREPDRVARSTSRGSRRERESSSLWRKSS", "md5" : "4d81afd24ddbf60ae3a731393853b1c0", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 133, "end" : 172, "location-fragments" : [ { "start" : 133, "end" : 172, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 141, "end" : 172, "location-fragments" : [ { "start" : 141, "end" : 172, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 32, "location-fragments" : [ { "start" : 1, "end" : 32, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910289.1 PREDICTED: uncharacterized protein LOC109039319 [Bemisia tabaci]", "id" : "XP_018910289.1" } ] },{ "sequence" : "MRIKFSAEMNRIPTVCVKTLVCLFVLVQCTGCSHLAKIYSRLNHEHRHEDDSDKYNYPLDKLMNRLGHNSSKDARTPSNLIDTSMDRYSRKSAAETSTWSPASAGGNALWKRRSVSGGAQKPRVTREETKDSRRRKLEGSLERRLYEDSDEDEEDEDEPIEEEMEAREYQDLDPFSYDADHRNVRHGASYMRFEQSEPSQQQRTSQQLSPMSKKKWELLGSSKKVDELFQASRKNGGVRKVGIPGVDVWVDPHPQKQAENHVLKIMRDGKCKWPRQKLIKVSESYPSMTKTYIPSCTILYRCGDDTGCCSLPTQKCTAKNSTTVELYFTTTRVEVRDGNRTVRQDVEKLTFTNDTECDCVEMMPRDMELERMIDHKKTGCTCPTEFSPRYMSNGLCTCDCFDKQNDCLRYKRGLKYFEHSDRLCIAEGRCEKPLCRFGVYEHKYGRCPKRHEKFQKFSKYIS", "md5" : "b66a60b224cd514280434b62d05dd823", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 66, "end" : 87, "location-fragments" : [ { "start" : 66, "end" : 87, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 169, "end" : 188, "location-fragments" : [ { "start" : 169, "end" : 188, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 69, "end" : 87, "location-fragments" : [ { "start" : 69, "end" : 87, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 109, "end" : 206, "location-fragments" : [ { "start" : 109, "end" : 206, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50278", "name" : "PDGF_2", "description" : "Platelet-derived growth factor (PDGF) family profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000072", "name" : "PDGF/VEGF_dom", "description" : "PDGF/VEGF domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "growth factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008083" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 274, "end" : 364, "score" : 11.439, "alignment" : "---------------PRQKLIKVSESYPSMTKTYI-PSCTILYRCGddtGCCSLPTQKCTAKNSTTVELYFTTTRVevRDGNRTvrqdVEKLTFTNDTECDCVEMMP", "location-fragments" : [ { "start" : 274, "end" : 364, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50278" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 147, "end" : 168, "location-fragments" : [ { "start" : 147, "end" : 168, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:2.10.90.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029034", "name" : "Cystine-knot_cytokine", "description" : "Cystine-knot cytokine", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 253, "end" : 362, "hmmStart" : 10, "hmmEnd" : 101, "hmmLength" : 103, "hmmBounds" : "COMPLETE", "evalue" : 2.2E-17, "score" : 64.8, "envelopeStart" : 253, "envelopeEnd" : 362, "postProcessed" : true, "location-fragments" : [ { "start" : 253, "end" : 362, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-17, "score" : 64.8, "model-ac" : "2gnnB00" }, { "signature" : { "accession" : "SM00141", "name" : "PDGF_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000072", "name" : "PDGF/VEGF_dom", "description" : "PDGF/VEGF domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "growth factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008083" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 269, "end" : 361, "hmmStart" : 1, "hmmEnd" : 91, "hmmLength" : 91, "hmmBounds" : "COMPLETE", "evalue" : 5.3E-4, "score" : 20.0, "location-fragments" : [ { "start" : 269, "end" : 361, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-4, "score" : 20.0, "model-ac" : "SM00141" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 123, "end" : 146, "location-fragments" : [ { "start" : 123, "end" : 146, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR21719", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 124, "end" : 456, "hmmStart" : 44, "hmmEnd" : 335, "hmmLength" : 339, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 110, "envelopeEnd" : 459, "location-fragments" : [ { "start" : 124, "end" : 456, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.5E-53, "familyName" : "UNCHARACTERIZED", "score" : 182.3, "model-ac" : "PTHR21719" }, { "signature" : { "accession" : "PF00341", "name" : "PDGF", "description" : "PDGF/VEGF domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000072", "name" : "PDGF/VEGF_dom", "description" : "PDGF/VEGF domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "growth factor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008083" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 274, "end" : 359, "hmmStart" : 3, "hmmEnd" : 82, "hmmLength" : 82, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.2E-9, "score" : 38.3, "envelopeStart" : 271, "envelopeEnd" : 359, "postProcessed" : true, "location-fragments" : [ { "start" : 274, "end" : 359, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-9, "score" : 38.3, "model-ac" : "PF00341" }, { "signature" : { "accession" : "SSF57501", "name" : "Cystine-knot cytokines", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029034", "name" : "Cystine-knot_cytokine", "description" : "Cystine-knot cytokine", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 261, "end" : 362, "hmmLength" : 100, "location-fragments" : [ { "start" : 261, "end" : 362, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.69E-13, "model-ac" : "0050683" } ], "xref" : [ { "name" : "XP_018910294.1 PREDICTED: uncharacterized protein LOC109039324 [Bemisia tabaci]", "id" : "XP_018910294.1" } ] },{ "sequence" : "MAPVTAELLDQHCSEVKPLKLENKWKAEQVEKMLQRFKLDGKTMLKMAEIFQREMELGLADKPSSLLMENTYVPELPNGTEEGKYLALDLGGTNFRVILVDLEKGRIVNERVKHYHISDELRLNCGIKLFDFLAECISEFVIENGLADRVLPMGFTFSFPMHQHALDSGILKVWTKSFACPGVEGKDAVKLLNEAIHRRGDNHVELICVLNDTTGTLMQGAMLDKDTAIGLILGTGTNACYLERAERVQHWEVERHGEKQVVIDIEWGAFGDNGCIDFVKTEFDRTVDEKSLIPKSFTFEKKIGGKFMGELVQVVLCSLTREGHLFNGIPSDKLLQHGHFRTSFVSGIEEDSINGTKGNTEKILDDLGLDYDDDDVKIVQYICHLVSLRAAQFVAICVSQILIRMSKPQVTVAVDGSLFKFHPRLRIWMEKYTKLLAPSHPFKIVLVQDGSGKGAALVSAIAKRITEKY", "md5" : "7872d16d18dfdf3528f8f0d95cefd799", "matches" : [ { "signature" : { "accession" : "G3DSA:3.30.420.40", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 71, "end" : 458, "hmmStart" : 2, "hmmEnd" : 429, "hmmLength" : 169, "hmmBounds" : "INCOMPLETE", "evalue" : 4.5E-147, "score" : 492.0, "envelopeStart" : 34, "envelopeEnd" : 459, "postProcessed" : true, "location-fragments" : [ { "start" : 449, "end" : 458, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 71, "end" : 222, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 3.9E-147, "score" : 492.2, "model-ac" : "3f9mA02" }, { "signature" : { "accession" : "G3DSA:3.40.367.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 448, "hmmStart" : 2, "hmmEnd" : 429, "hmmLength" : 291, "hmmBounds" : "INCOMPLETE", "evalue" : 4.5E-147, "score" : 492.0, "envelopeStart" : 34, "envelopeEnd" : 459, "postProcessed" : true, "location-fragments" : [ { "start" : 223, "end" : 448, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 35, "end" : 70, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 3.9E-147, "score" : 492.2, "model-ac" : "3f9mA01" }, { "signature" : { "accession" : "PR00475", "name" : "HEXOKINASE", "description" : "Hexokinase family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : null }, "locations" : [ { "start" : 379, "end" : 401, "pvalue" : 9.32E-7, "score" : 29.83, "motifNumber" : 6, "location-fragments" : [ { "start" : 379, "end" : 401, "dc-status" : "CONTINUOUS" } ] }, { "start" : 445, "end" : 461, "pvalue" : 6.96E-10, "score" : 57.18, "motifNumber" : 7, "location-fragments" : [ { "start" : 445, "end" : 461, "dc-status" : "CONTINUOUS" } ] }, { "start" : 153, "end" : 178, "pvalue" : 1.19E-12, "score" : 57.51, "motifNumber" : 2, "location-fragments" : [ { "start" : 153, "end" : 178, "dc-status" : "CONTINUOUS" } ] }, { "start" : 297, "end" : 319, "pvalue" : 9.03E-9, "score" : 42.37, "motifNumber" : 5, "location-fragments" : [ { "start" : 297, "end" : 319, "dc-status" : "CONTINUOUS" } ] }, { "start" : 206, "end" : 222, "pvalue" : 5.05E-6, "score" : 38.3, "motifNumber" : 3, "location-fragments" : [ { "start" : 206, "end" : 222, "dc-status" : "CONTINUOUS" } ] }, { "start" : 86, "end" : 102, "pvalue" : 1.04E-11, "score" : 74.42, "motifNumber" : 1, "location-fragments" : [ { "start" : 86, "end" : 102, "dc-status" : "CONTINUOUS" } ] }, { "start" : 229, "end" : 243, "pvalue" : 3.12E-10, "score" : 68.53, "motifNumber" : 4, "location-fragments" : [ { "start" : 229, "end" : 243, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-56, "graphscan" : "IIIIIiI", "model-ac" : "PR00475" }, { "signature" : { "accession" : "PTHR19443:SF54", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 20, "end" : 466, "hmmStart" : 7, "hmmEnd" : 456, "hmmLength" : 461, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 469, "location-fragments" : [ { "start" : 20, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-178, "familyName" : "", "score" : 595.8, "model-ac" : "PTHR19443:SF54" }, { "signature" : { "accession" : "PF00349", "name" : "Hexokinase_1", "description" : "Hexokinase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022672", "name" : "Hexokinase_N", "description" : "Hexokinase, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Streptomycin biosynthesis", "databaseName" : "KEGG", "id" : "00521+2.7.1.1" }, { "name" : "Neomycin, kanamycin and gentamicin biosynthesis", "databaseName" : "KEGG", "id" : "00524+2.7.1.1" }, { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+2.7.1.1" }, { "name" : "Glycolysis / Gluconeogenesis", "databaseName" : "KEGG", "id" : "00010+2.7.1.1" }, { "name" : "Glycolysis", "databaseName" : "Reactome", "id" : "R-HSA-70171" }, { "name" : "Galactose metabolism", "databaseName" : "KEGG", "id" : "00052+2.7.1.1" }, { "name" : "Starch and sucrose metabolism", "databaseName" : "KEGG", "id" : "00500+2.7.1.1" }, { "name" : "Fructose and mannose metabolism", "databaseName" : "KEGG", "id" : "00051+2.7.1.1" } ] } }, "locations" : [ { "start" : 30, "end" : 220, "hmmStart" : 2, "hmmEnd" : 197, "hmmLength" : 199, "hmmBounds" : "INCOMPLETE", "evalue" : 2.5E-61, "score" : 207.0, "envelopeStart" : 29, "envelopeEnd" : 222, "postProcessed" : true, "location-fragments" : [ { "start" : 30, "end" : 220, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-61, "score" : 207.6, "model-ac" : "PF00349" }, { "signature" : { "accession" : "cd00012", "name" : "NBD_sugar-kinase_HSP70_actin", "description" : "NBD_sugar-kinase_HSP70_actin", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 86, "end" : 254, "sites" : [ { "description" : "nucleotide binding site", "numLocations" : 11, "siteLocations" : [ { "start" : 90, "end" : 90, "residue" : "L" }, { "start" : 92, "end" : 92, "residue" : "G" }, { "start" : 96, "end" : 96, "residue" : "R" }, { "start" : 235, "end" : 235, "residue" : "T" }, { "start" : 212, "end" : 212, "residue" : "D" }, { "start" : 234, "end" : 234, "residue" : "G" }, { "start" : 89, "end" : 89, "residue" : "D" }, { "start" : 94, "end" : 94, "residue" : "N" }, { "start" : 232, "end" : 232, "residue" : "I" }, { "start" : 233, "end" : 233, "residue" : "L" }, { "start" : 91, "end" : 91, "residue" : "G" } ] } ], "evalue" : 1.00561E-10, "score" : 58.7543, "location-fragments" : [ { "start" : 86, "end" : 254, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00012" }, { "signature" : { "accession" : "PTHR19443", "name" : "HEXOKINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR001312", "name" : "Hexokinase", "description" : "Hexokinase", "type" : "FAMILY", "goXRefs" : [ { "name" : "cellular glucose homeostasis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0001678" }, { "name" : "hexokinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004396" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "glucose binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005536" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Galactose metabolism", "databaseName" : "KEGG", "id" : "00052+2.7.1.1" }, { "name" : "Fructose and mannose metabolism", "databaseName" : "KEGG", "id" : "00051+2.7.1.1" }, { "name" : "Starch and sucrose metabolism", "databaseName" : "KEGG", "id" : "00500+2.7.1.1" }, { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+2.7.1.1" }, { "name" : "Neomycin, kanamycin and gentamicin biosynthesis", "databaseName" : "KEGG", "id" : "00524+2.7.1.1" }, { "name" : "Streptomycin biosynthesis", "databaseName" : "KEGG", "id" : "00521+2.7.1.1" }, { "name" : "Glycolysis", "databaseName" : "Reactome", "id" : "R-HSA-70171" }, { "name" : "Glycolysis / Gluconeogenesis", "databaseName" : "KEGG", "id" : "00010+2.7.1.1" } ] } }, "locations" : [ { "start" : 20, "end" : 466, "hmmStart" : 7, "hmmEnd" : 456, "hmmLength" : 461, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 469, "location-fragments" : [ { "start" : 20, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-178, "familyName" : "", "score" : 595.8, "model-ac" : "PTHR19443" }, { "signature" : { "accession" : "PS00378", "name" : "HEXOKINASE_1", "description" : "Hexokinase domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019807", "name" : "Hexokinase_BS", "description" : "Hexokinase, binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "hexokinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004396" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "glycolytic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006096" } ], "pathwayXRefs" : [ { "name" : "Fructose and mannose metabolism", "databaseName" : "KEGG", "id" : "00051+2.7.1.1" }, { "name" : "Neomycin, kanamycin and gentamicin biosynthesis", "databaseName" : "KEGG", "id" : "00524+2.7.1.1" }, { "name" : "Starch and sucrose metabolism", "databaseName" : "KEGG", "id" : "00500+2.7.1.1" }, { "name" : "Streptomycin biosynthesis", "databaseName" : "KEGG", "id" : "00521+2.7.1.1" }, { "name" : "Galactose metabolism", "databaseName" : "KEGG", "id" : "00052+2.7.1.1" }, { "name" : "Glycolysis / Gluconeogenesis", "databaseName" : "KEGG", "id" : "00010+2.7.1.1" }, { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+2.7.1.1" }, { "name" : "Glycolysis", "databaseName" : "Reactome", "id" : "R-HSA-70171" } ] } }, "locations" : [ { "start" : 153, "end" : 178, "level" : "STRONG", "cigarAlignment" : "8M5I2M3I1M2I3M1I1M", "alignment" : "MGFTFSFPmhqhaLDsgiLkvWTKsF", "location-fragments" : [ { "start" : 153, "end" : 178, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00378" }, { "signature" : { "accession" : "PS51748", "name" : "HEXOKINASE_2", "description" : "Hexokinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001312", "name" : "Hexokinase", "description" : "Hexokinase", "type" : "FAMILY", "goXRefs" : [ { "name" : "cellular glucose homeostasis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0001678" }, { "name" : "hexokinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004396" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "glucose binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005536" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Galactose metabolism", "databaseName" : "KEGG", "id" : "00052+2.7.1.1" }, { "name" : "Fructose and mannose metabolism", "databaseName" : "KEGG", "id" : "00051+2.7.1.1" }, { "name" : "Starch and sucrose metabolism", "databaseName" : "KEGG", "id" : "00500+2.7.1.1" }, { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+2.7.1.1" }, { "name" : "Neomycin, kanamycin and gentamicin biosynthesis", "databaseName" : "KEGG", "id" : "00524+2.7.1.1" }, { "name" : "Streptomycin biosynthesis", "databaseName" : "KEGG", "id" : "00521+2.7.1.1" }, { "name" : "Glycolysis", "databaseName" : "Reactome", "id" : "R-HSA-70171" }, { "name" : "Glycolysis / Gluconeogenesis", "databaseName" : "KEGG", "id" : "00010+2.7.1.1" } ] } }, "locations" : [ { "start" : 24, "end" : 460, "score" : 44.657, "alignment" : "KWKAEQVEKMLQRFKLDGKTMLKMAEIFQREMELGLADK-PSSLLMENTYVPELPNGTEEGKYLALDLGGTNFRVILVDLEKGR--IVNERVKHYHISDELRLNCGIKLFDFLAECISEFV-IENGLADRVLPMGFTFSFPMHQHALDSGILKVWTKSFACPGVEGKDAVKLLNEAIHRRGDNHVELICVLNDTTGTLMQGAMLDKDTAIGLILGTGTNACYLERAERVQHWEVERHGEKQVVIDIEWGAFGDNGCIDFVKTEFDRTVDEKSLIPKSFTFEKKIGGKFMGELVQVVLCSLTREGHLFNGIPSDKLLQHGHFRTSFVSGIEEDSInGTKGNTEKILDDL-GLDYDDDDVKIVQYICHLVSLRAAQFVAICVSQILIRMSKPQ---VTVAVDGSLFKFHPRLRIWMEKYTKLLAPSHPFKIV--LVQDGSGKGAALVSA", "location-fragments" : [ { "start" : 24, "end" : 460, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51748" }, { "signature" : { "accession" : "PF03727", "name" : "Hexokinase_2", "description" : "Hexokinase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022673", "name" : "Hexokinase_C", "description" : "Hexokinase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Amino sugar and nucleotide sugar metabolism", "databaseName" : "KEGG", "id" : "00520+2.7.1.1" }, { "name" : "Fructose and mannose metabolism", "databaseName" : "KEGG", "id" : "00051+2.7.1.1" }, { "name" : "Starch and sucrose metabolism", "databaseName" : "KEGG", "id" : "00500+2.7.1.1" }, { "name" : "Glycolysis / Gluconeogenesis", "databaseName" : "KEGG", "id" : "00010+2.7.1.1" }, { "name" : "Galactose metabolism", "databaseName" : "KEGG", "id" : "00052+2.7.1.1" }, { "name" : "Streptomycin biosynthesis", "databaseName" : "KEGG", "id" : "00521+2.7.1.1" }, { "name" : "Neomycin, kanamycin and gentamicin biosynthesis", "databaseName" : "KEGG", "id" : "00524+2.7.1.1" }, { "name" : "Glycolysis", "databaseName" : "Reactome", "id" : "R-HSA-70171" } ] } }, "locations" : [ { "start" : 229, "end" : 460, "hmmStart" : 2, "hmmEnd" : 240, "hmmLength" : 241, "hmmBounds" : "INCOMPLETE", "evalue" : 3.6E-68, "score" : 229.6, "envelopeStart" : 228, "envelopeEnd" : 461, "postProcessed" : true, "location-fragments" : [ { "start" : 229, "end" : 460, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-68, "score" : 230.4, "model-ac" : "PF03727" }, { "signature" : { "accession" : "SSF53067", "name" : "Actin-like ATPase domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR043129", "name" : "ATPase_NBD", "description" : "ATPase, nucleotide binding domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 27, "end" : 224, "hmmLength" : 222, "location-fragments" : [ { "start" : 27, "end" : 224, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.53E-62, "model-ac" : "0045955" }, { "signature" : { "accession" : "SSF53067", "name" : "Actin-like ATPase domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR043129", "name" : "ATPase_NBD", "description" : "ATPase, nucleotide binding domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 226, "end" : 466, "hmmLength" : 262, "location-fragments" : [ { "start" : 226, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.16E-67, "model-ac" : "0039007" } ], "xref" : [ { "name" : "XP_018909595.1 PREDICTED: hexokinase-1-like [Bemisia tabaci]", "id" : "XP_018909595.1" } ] },{ "sequence" : "MEDMDHRESDLEGSMSSPEMSDGEDMGDEDIDDQMHREIEEHNDDDRKKLRMAEKMAKLTKSALFHERDRIIRRGGSGLSFSQAEDMGLLTPTATAASPMVPPPPFSLPLPFPFLHPAAALPFLPPSAPVNVHQTSSASSHSSESSSSSQQTWSFEEQFKQVRQLYELSDDPKRKEFLDDLFSFMQRRGTPINRLPIMAKSVLDLYELYNLVIQRGGLVDVINKKLWQEIIKGLNLPSSITSAAFTLRTQYMKYLYPYECEKKRLSSPSELQAAIDGNRREGRRGSYGAMAYADMVHRSPTSMVDIPQSVSPAQPQPQPQPLNLVTTTSPRRPHSAHSATLNGNGNGHHNNHHSAHHPSRDSTATVNSHLSSHMLPPSSGDESSRPGSNNSSLVVSMDINGIMYQGVLFAQSATNSASQNSRPSMIAYMQHNHDYLFRCDSKDSQSLS", "md5" : "e24a6d4c110ff413b93a14b5b3dcbaee", "matches" : [ { "signature" : { "accession" : "PS51011", "name" : "ARID", "description" : "ARID domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001606", "name" : "ARID_dom", "description" : "ARID DNA-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 171, "end" : 263, "score" : 31.145, "alignment" : "DPKRKEFLDDLFSFMQRRGTPINRLPIMAKSVLDLYELYNLVIQRGGLVDVINKKLWQEIIKGLNLPSSITSAAFTLRTQYMKYLYPYECEKK", "location-fragments" : [ { "start" : 171, "end" : 263, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51011" }, { "signature" : { "accession" : "PTHR15348:SF1", "name" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 13, "end" : 291, "hmmStart" : 77, "hmmEnd" : 357, "hmmLength" : 588, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 311, "location-fragments" : [ { "start" : 13, "end" : 291, "dc-status" : "CONTINUOUS" } ] }, { "start" : 385, "end" : 422, "hmmStart" : 510, "hmmEnd" : 546, "hmmLength" : 588, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 328, "envelopeEnd" : 446, "location-fragments" : [ { "start" : 385, "end" : 422, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-94, "familyName" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A", "score" : 318.9, "model-ac" : "PTHR15348:SF1" }, { "signature" : { "accession" : "PTHR15348", "name" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 385, "end" : 422, "hmmStart" : 510, "hmmEnd" : 546, "hmmLength" : 588, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 328, "envelopeEnd" : 446, "location-fragments" : [ { "start" : 385, "end" : 422, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-94, "familyName" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A", "score" : 318.9, "model-ac" : "PTHR15348" }, { "signature" : { "accession" : "PS51486", "name" : "REKLES", "description" : "REKLES domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR023334", "name" : "REKLES_domain", "description" : "REKLES domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 324, "end" : 415, "score" : 11.035, "alignment" : "LVTTTSPRRPHSAHSATLNGNGNGHHNNHHSAHHPSRdSTATVNSHLSSHMLPPSSgdESSRPGS-------NNSSLVVSMDINGIMYQGVLFAQSATN", "location-fragments" : [ { "start" : 324, "end" : 415, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51486" }, { "signature" : { "accession" : "cd16881", "name" : "ARID_Dri-like", "description" : "ARID_Dri-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 155, "end" : 279, "sites" : [ { "description" : "DNA binding site", "numLocations" : 21, "siteLocations" : [ { "start" : 231, "end" : 231, "residue" : "I" }, { "start" : 246, "end" : 246, "residue" : "T" }, { "start" : 200, "end" : 200, "residue" : "K" }, { "start" : 241, "end" : 241, "residue" : "T" }, { "start" : 195, "end" : 195, "residue" : "L" }, { "start" : 242, "end" : 242, "residue" : "S" }, { "start" : 196, "end" : 196, "residue" : "P" }, { "start" : 198, "end" : 198, "residue" : "M" }, { "start" : 240, "end" : 240, "residue" : "I" }, { "start" : 244, "end" : 244, "residue" : "A" }, { "start" : 227, "end" : 227, "residue" : "W" }, { "start" : 225, "end" : 225, "residue" : "K" }, { "start" : 248, "end" : 248, "residue" : "R" }, { "start" : 197, "end" : 197, "residue" : "I" }, { "start" : 228, "end" : 228, "residue" : "Q" }, { "start" : 239, "end" : 239, "residue" : "S" }, { "start" : 245, "end" : 245, "residue" : "F" }, { "start" : 199, "end" : 199, "residue" : "A" }, { "start" : 278, "end" : 278, "residue" : "N" }, { "start" : 279, "end" : 279, "residue" : "R" }, { "start" : 194, "end" : 194, "residue" : "R" } ] } ], "evalue" : 4.58621E-91, "score" : 269.843, "location-fragments" : [ { "start" : 155, "end" : 279, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd16881" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 52, "location-fragments" : [ { "start" : 1, "end" : 52, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF01388", "name" : "ARID", "description" : "ARID/BRIGHT DNA binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001606", "name" : "ARID_dom", "description" : "ARID DNA-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 174, "end" : 259, "hmmStart" : 2, "hmmEnd" : 90, "hmmLength" : 90, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.2E-21, "score" : 74.7, "envelopeStart" : 173, "envelopeEnd" : 259, "postProcessed" : true, "location-fragments" : [ { "start" : 174, "end" : 259, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-21, "score" : 75.5, "model-ac" : "PF01388" }, { "signature" : { "accession" : "G3DSA:1.10.150.60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036431", "name" : "ARID_dom_sf", "description" : "ARID DNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 152, "end" : 279, "hmmStart" : 2, "hmmEnd" : 128, "hmmLength" : 128, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-60, "score" : 203.6, "envelopeStart" : 152, "envelopeEnd" : 279, "postProcessed" : true, "location-fragments" : [ { "start" : 152, "end" : 279, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-60, "score" : 204.3, "model-ac" : "1c20A00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 30, "end" : 52, "location-fragments" : [ { "start" : 30, "end" : 52, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 320, "end" : 349, "location-fragments" : [ { "start" : 320, "end" : 349, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF46774", "name" : "ARID-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036431", "name" : "ARID_dom_sf", "description" : "ARID DNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 156, "end" : 277, "hmmLength" : 128, "location-fragments" : [ { "start" : 156, "end" : 277, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.19E-36, "model-ac" : "0046063" }, { "signature" : { "accession" : "PTHR15348", "name" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 13, "end" : 291, "hmmStart" : 77, "hmmEnd" : 357, "hmmLength" : 588, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 311, "location-fragments" : [ { "start" : 13, "end" : 291, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-94, "familyName" : "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A", "score" : 318.9, "model-ac" : "PTHR15348" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 360, "end" : 392, "location-fragments" : [ { "start" : 360, "end" : 392, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM01014", "name" : "ARID_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 168, "end" : 259, "hmmStart" : 1, "hmmEnd" : 97, "hmmLength" : 97, "hmmBounds" : "COMPLETE", "evalue" : 8.3E-36, "score" : 135.0, "location-fragments" : [ { "start" : 168, "end" : 259, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-36, "score" : 135.0, "model-ac" : "SM01014" }, { "signature" : { "accession" : "SM00501", "name" : "bright_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001606", "name" : "ARID_dom", "description" : "ARID DNA-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 172, "end" : 264, "hmmStart" : 1, "hmmEnd" : 95, "hmmLength" : 95, "hmmBounds" : "COMPLETE", "evalue" : 6.5E-37, "score" : 138.6, "location-fragments" : [ { "start" : 172, "end" : 264, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-37, "score" : 138.6, "model-ac" : "SM00501" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 300, "end" : 392, "location-fragments" : [ { "start" : 300, "end" : 392, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909715.1 PREDICTED: protein dead ringer homolog isoform X1 [Bemisia tabaci]", "id" : "XP_018909715.1" } ] },{ "sequence" : "MEISSSDEDIVLALLLADEEEELQQNRRQIWTHPINLRRPELGEFNTLFPDLLNDEQRFFKFFRMSANKFFELVNTLPGLQKQETNYRKSISPMERLAVTLKVLGHGDSIYTTACSYRMGESTVRGIVFETSKLIWETLKDTWMPKPTEETWLRNAERFWTLWNYPNCIGAIDGKHVVFEKPRKSGSLFFNYKKEFSIVLLALVDADYRFITVDVGSYGRNSDGGIFRSSSLGKSLANGTLNIPPPKALPYSEVTVPMVIVGDEAFPLLTNSMRPFPGAYLGDDVPKKIYNYRHSRARRVSENAFGILAKKFRIYGKKFSFQPETMDYIILATTILHNFLRDDKCCWQPGEFEMDAVTEGLGEIPGIGGNNPRDAFEIRDIYMAYFMSEAGSVPWQWQATLSAQRDT", "md5" : "53ee7e67071fc21a05166d78d026da1d", "matches" : [ { "signature" : { "accession" : "PTHR22930", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 392, "hmmStart" : 4, "hmmEnd" : 371, "hmmLength" : 377, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 22, "envelopeEnd" : 398, "location-fragments" : [ { "start" : 25, "end" : 392, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-116, "familyName" : "SIMILAR TO ENSANGP00000010363", "score" : 390.3, "model-ac" : "PTHR22930" }, { "signature" : { "accession" : "PTHR22930:SF161", "name" : "SIMILAR TO ENSANGP00000010363", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 392, "hmmStart" : 4, "hmmEnd" : 371, "hmmLength" : 377, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 22, "envelopeEnd" : 398, "location-fragments" : [ { "start" : 25, "end" : 392, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-116, "familyName" : "SIMILAR TO ENSANGP00000010363", "score" : 390.3, "model-ac" : "PTHR22930:SF161" }, { "signature" : { "accession" : "PF13359", "name" : "DDE_Tnp_4", "description" : "DDE superfamily endonuclease", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR027806", "name" : "HARBI1_dom", "description" : "Harbinger transposase-derived nuclease domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 172, "end" : 338, "hmmStart" : 1, "hmmEnd" : 158, "hmmLength" : 158, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-28, "score" : 99.5, "envelopeStart" : 172, "envelopeEnd" : 338, "postProcessed" : true, "location-fragments" : [ { "start" : 172, "end" : 338, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-28, "score" : 100.0, "model-ac" : "PF13359" } ], "xref" : [ { "name" : "XP_018910442.1 PREDICTED: uncharacterized protein LOC109039427 [Bemisia tabaci]", "id" : "XP_018910442.1" } ] },{ "sequence" : "MEFFSSLVANLNLRRRNFPSQESRIGINYFPSELSERIENEIEDDTSDGDGVSMLSRPVRFSRSRTSLLSQKFAAIAPRPCSRLEIIFEKSQRLQNEEIVDNLLSSLDILLPSCKPEISEENDNSLKVIIDSNKKINDHTKWNPSQIKEDKKVDVSQCDSAVKQAPMYPGGGGNKMQGTYRFPTGDSNSGAGSQPNYSSNMNNSGPGFRGPRPGFSSLLSNVSSVDLSPFRGGAPIRFRLGTTPRMNPKKVQDKVPSAASQASSSPQSDSPTKEDEDVDLYSDIEHDPHEDVDEDKNFGTLEPPPEPPALLMGLGDEGTDEEEALVIDDKGADVYDPAEPCDDSNDASDSRNDEPVEAMNLTKPSSGYLHSPTYNDIVAQHDDKIGNGSSYDGVPKMMEPPPIPDALKIMEPPPFPSELLSKEIQGDDDEECPNFSLYSSASMNLVKKSSSVLDIPIPAQSNLDIPIPTQPNLDIPMPGPPNLDIPVPGSPTVANIPVPNSGSKTEKSTKEKKKKKKKKPLMYSVPTLEETILKERLGNYSSEDNTDSDDSEEKVKIIIPKRKKKASKKSKKKLAEAEKVDEMNDDAFENVNGEKKPEEKEEEEKENEEEKIVEVNVELDDNDEQSNFDDVSESKAPEKEGGDETEGDTQDEVESKIVSESSMDSIRPQVDEQTIDDNQETVSSLDNSDVSKLPDDKSDSSKMAILSNEGKEKLYDGEDESSIQGDILDIEAEANLQDATSIPDEQDDIKSSTPSKSNAQKSDGLVDITDEEMSEYDHSREEPSNKLDSLNTEAISEDEASIVDGNKESEQSCPTLPGLEGLQTDPISDSDGNAFDESNYSADKESEYDGGKRRKKKKKVQKEKEQSASENEDANVSKSKEKRNSADFEEGEIVDDKPKSSSKKDKKKKAKDKEAKENLDRSKSDHEKDKEKDKKQKKSKDGKSKDKDSVLQSSENKSSEENKEGSPSQSAADVNWKKLSKSTKDRNYRDGKGKPTNDKGRKSPERSTPKEREKKKEKRKELERYNVRKVLGEKVRLIGKDDFGRDLSLNRSMSRSRSRSRNRKGKGKSRSTSRSPYRSPVRSRAARSRSRSRSRSRSRRRLGRKRSRSKNRTLRRSYDRSRSKSRGRSRDRLRKKRASSRDRLRRSLSKGRVSRKKKKSVERRRNRSYSPEYSPARKRRSNSRYSFSPSWSSYSYSPSPGYSRSYSLSPSPSWSPENRALVYNREKNRPPKNITVIVPNEDANAKKKGKKRLSKKNKENEKRRKKRDRSPAPSKEVFTSGDNILVSVNFSNNKNDGTMGSLLHTNEYSTARRRSVEAEPPAKKSKETKNKEKKSKNSTPKKSRSARAVAVNEAAKNAKPIAVIDLNMSPFREETPSPKEVIVVTDSDLEAEQIEKEAPTSNRKVSRKSGSGRERDRDRDRDRDRDRDRNRDRDLGPPTSVSQPESPINDFMNTSAGGPKTPPEPRVAFSISSKQPQMRTMINPLMDGDEEEEQMEEANNEAEMNEIFSKGPNTPPEPPPDTNTPASPPTTPYDPFDPTKSRSPSPELGEQTSTPVNLRDGNKAHDTLSPNVLESNDLDSRNKTSPQVPDENKKTPDNLRSLQKDTIPILESPKQSSPNVSGVNDSNDGVVMKILGQAKIDLTTYKSPEPIAGTPRSTQLTPKPITPSKQSILSVSRAPAPASANKIPVYTPSITLNGEKMDEAPMDISGDSPYSPEPFEAEDLFEPPPISPPRTANKLPMPPIIRSSLTKANKSKFDALFGSLTRKTNTKQLKPVPYTPKPIIPSIKGTKAQKQMKGSKKEVGVKMDEDQLKILDDLPSSAVEMQVKDKYLKKLNRQERVVEEVKLVLKPHYAKKHIAKEDYKEILRRAVPKICHNRSGEINPQKIQMLIEAYVRKFQAKTSKKKGGAETTTNNTSNLSKRSKATRS", "md5" : "710336e4ceb227304574edd5b1435111", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1650, "end" : 1678, "location-fragments" : [ { "start" : 1650, "end" : 1678, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1436, "end" : 1456, "location-fragments" : [ { "start" : 1436, "end" : 1456, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 963, "end" : 977, "location-fragments" : [ { "start" : 963, "end" : 977, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 978, "end" : 1048, "location-fragments" : [ { "start" : 978, "end" : 1048, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 467, "end" : 1181, "location-fragments" : [ { "start" : 467, "end" : 1181, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 838, "end" : 852, "location-fragments" : [ { "start" : 838, "end" : 852, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1512, "end" : 1535, "location-fragments" : [ { "start" : 1512, "end" : 1535, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 254, "end" : 269, "location-fragments" : [ { "start" : 254, "end" : 269, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 603, "end" : 627, "location-fragments" : [ { "start" : 603, "end" : 627, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1385, "end" : 1435, "location-fragments" : [ { "start" : 1385, "end" : 1435, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1485, "end" : 1505, "location-fragments" : [ { "start" : 1485, "end" : 1505, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1696, "end" : 1747, "location-fragments" : [ { "start" : 1696, "end" : 1747, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 236, "end" : 432, "location-fragments" : [ { "start" : 236, "end" : 432, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 270, "end" : 300, "location-fragments" : [ { "start" : 270, "end" : 300, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1584, "end" : 1600, "location-fragments" : [ { "start" : 1584, "end" : 1600, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1544, "end" : 1560, "location-fragments" : [ { "start" : 1544, "end" : 1560, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1902, "end" : 1928, "location-fragments" : [ { "start" : 1902, "end" : 1928, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1608, "end" : 1626, "location-fragments" : [ { "start" : 1608, "end" : 1626, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1056, "end" : 1071, "location-fragments" : [ { "start" : 1056, "end" : 1071, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 675, "end" : 689, "location-fragments" : [ { "start" : 675, "end" : 689, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1127, "end" : 1164, "location-fragments" : [ { "start" : 1127, "end" : 1164, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 397, "end" : 411, "location-fragments" : [ { "start" : 397, "end" : 411, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1249, "end" : 1263, "location-fragments" : [ { "start" : 1249, "end" : 1263, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1646, "end" : 1679, "location-fragments" : [ { "start" : 1646, "end" : 1679, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 168, "end" : 212, "location-fragments" : [ { "start" : 168, "end" : 212, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1297, "end" : 1626, "location-fragments" : [ { "start" : 1297, "end" : 1626, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1310, "end" : 1334, "location-fragments" : [ { "start" : 1310, "end" : 1334, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1568, "end" : 1583, "location-fragments" : [ { "start" : 1568, "end" : 1583, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 536, "end" : 559, "location-fragments" : [ { "start" : 536, "end" : 559, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 471, "end" : 487, "location-fragments" : [ { "start" : 471, "end" : 487, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 916, "end" : 936, "location-fragments" : [ { "start" : 916, "end" : 936, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 628, "end" : 643, "location-fragments" : [ { "start" : 628, "end" : 643, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 598, "end" : 625, "location-fragments" : [ { "start" : 598, "end" : 625, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1084, "end" : 1113, "location-fragments" : [ { "start" : 1084, "end" : 1113, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1222, "end" : 1280, "location-fragments" : [ { "start" : 1222, "end" : 1280, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 180, "end" : 206, "location-fragments" : [ { "start" : 180, "end" : 206, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 571, "end" : 602, "location-fragments" : [ { "start" : 571, "end" : 602, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1905, "end" : 1928, "location-fragments" : [ { "start" : 1905, "end" : 1928, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1722, "end" : 1739, "location-fragments" : [ { "start" : 1722, "end" : 1739, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 765, "end" : 787, "location-fragments" : [ { "start" : 765, "end" : 787, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 862, "end" : 962, "location-fragments" : [ { "start" : 862, "end" : 962, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1165, "end" : 1179, "location-fragments" : [ { "start" : 1165, "end" : 1179, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12618", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1201, "end" : 1907, "hmmStart" : 913, "hmmEnd" : 1449, "hmmLength" : 1450, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1189, "envelopeEnd" : 1908, "location-fragments" : [ { "start" : 1201, "end" : 1907, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-45, "familyName" : "FAMILY NOT NAMED", "score" : 158.2, "model-ac" : "PTHR12618" } ], "xref" : [ { "name" : "XP_018910054.1 PREDICTED: serine/arginine repetitive matrix protein 2-like isoform X4 [Bemisia tabaci]", "id" : "XP_018910054.1" }, { "name" : "XP_018910055.1 PREDICTED: serine/arginine repetitive matrix protein 2-like isoform X4 [Bemisia tabaci]", "id" : "XP_018910055.1" } ] },{ "sequence" : "MSLADELLADLEDGDEQVDEFMVEDIDIKPDIKPNIKPIEDDIKAVSIHQLATLSSSDRLKYVMGEIEKYQSMPHSIDIVGPVEADSEYQLIVEANNLAVEIDNEIVVIHRFTREKYSKRFPELESLVASPLEYMMTVRELGNDLDQAKNNEKLQQFLTPAIIMVVSITASTAQGQPLTDQELHDVFEACDMAAELNRCKQQIYEYVESRMTFIAPNLSAIVGASTAAKLMGVAGGLTSLSKMPACNVQLLGSQKKTLAGFAQASILPNTGFIFYSDFVESLPAELRKKAARIIAAKSTLAARVDACHEAPDGNIGRMLREEIEKKFDKLTEPPPVKFVKPLPKPIDPSRKKRGGKRVRKNKERYAMTELRKQANRLNFAEIDDDAYQDDLGYSRGTIGKTGTGRIRAAQVDEKTKVRVSKTLQKHMQKQQVYGGSTTVKRQISGTASSVAFTPLQGLEIVNPQAAEKRTNESSAKYFSNVAGFIKVKKSES", "md5" : "45c9810acf830f444cd54741053f7dfb", "matches" : [ { "signature" : { "accession" : "PF01798", "name" : "Nop", "description" : "snoRNA binding domain, fibrillarin", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002687", "name" : "Nop_dom", "description" : "Nop domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 99, "end" : 329, "hmmStart" : 2, "hmmEnd" : 232, "hmmLength" : 232, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.0E-79, "score" : 265.3, "envelopeStart" : 98, "envelopeEnd" : 329, "postProcessed" : true, "location-fragments" : [ { "start" : 99, "end" : 329, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-79, "score" : 266.0, "model-ac" : "PF01798" }, { "signature" : { "accession" : "G3DSA:1.10.150.460", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 122, "end" : 174, "hmmStart" : 2, "hmmEnd" : 118, "hmmLength" : 52, "hmmBounds" : "INCOMPLETE", "evalue" : 3.5E-11, "score" : 45.4, "envelopeStart" : 90, "envelopeEnd" : 209, "postProcessed" : true, "location-fragments" : [ { "start" : 122, "end" : 174, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-11, "score" : 46.4, "model-ac" : "3icxA02" }, { "signature" : { "accession" : "SM00931", "name" : "NOSIC_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR012976", "name" : "NOSIC", "description" : "NOSIC", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 91, "end" : 143, "hmmStart" : 1, "hmmEnd" : 53, "hmmLength" : 53, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-19, "score" : 80.0, "location-fragments" : [ { "start" : 91, "end" : 143, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-19, "score" : 80.0, "model-ac" : "SM00931" }, { "signature" : { "accession" : "SSF89124", "name" : "Nop domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036070", "name" : "Nop_dom_sf", "description" : "Nop domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 85, "end" : 331, "hmmLength" : 249, "location-fragments" : [ { "start" : 85, "end" : 331, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.02E-83, "model-ac" : "0054436" }, { "signature" : { "accession" : "G3DSA:1.10.287.660", "name" : "Helix hairpin bin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029012", "name" : "Helix_hairpin_bin_sf", "description" : "Helix hairpin bin domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 92, "end" : 208, "hmmStart" : 2, "hmmEnd" : 118, "hmmLength" : 76, "hmmBounds" : "INCOMPLETE", "evalue" : 3.5E-11, "score" : 45.4, "envelopeStart" : 90, "envelopeEnd" : 209, "postProcessed" : true, "location-fragments" : [ { "start" : 175, "end" : 208, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 92, "end" : 121, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.7E-11, "score" : 46.4, "model-ac" : "3icxA01" }, { "signature" : { "accession" : "G3DSA:1.10.246.90", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042239", "name" : "Nop_C", "description" : "Nop, C-terminal domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 216, "end" : 331, "hmmStart" : 1, "hmmEnd" : 114, "hmmLength" : 116, "hmmBounds" : "COMPLETE", "evalue" : 8.4E-43, "score" : 146.8, "envelopeStart" : 216, "envelopeEnd" : 331, "postProcessed" : true, "location-fragments" : [ { "start" : 216, "end" : 331, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.7E-43, "score" : 147.9, "model-ac" : "2ozbE02" }, { "signature" : { "accession" : "PS51358", "name" : "NOP", "description" : "Nop domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002687", "name" : "Nop_dom", "description" : "Nop domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 214, "end" : 332, "score" : 40.385, "alignment" : "IAPNLSAIVGASTAAKLMGVAGGLTSLSKMPACNVQLLGSQKKTLAGFAQASILPNTGFIFYSDFVESLPAELRKKAARIIAAKSTLAARVDACHEAPDGNIGRMLREEIEKKFDKLTE", "location-fragments" : [ { "start" : 214, "end" : 332, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51358" }, { "signature" : { "accession" : "PF09785", "name" : "Prp31_C", "description" : "Prp31 C terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR019175", "name" : "Prp31_C", "description" : "Prp31 C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "mRNA Splicing - Major Pathway", "databaseName" : "Reactome", "id" : "R-HSA-72163" } ] } }, "locations" : [ { "start" : 337, "end" : 463, "hmmStart" : 2, "hmmEnd" : 124, "hmmLength" : 124, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.9E-44, "score" : 151.0, "envelopeStart" : 336, "envelopeEnd" : 463, "postProcessed" : true, "location-fragments" : [ { "start" : 337, "end" : 463, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-44, "score" : 152.1, "model-ac" : "PF09785" }, { "signature" : { "accession" : "PTHR13904", "name" : "PRE-MRNA SPLICING FACTOR PRP31", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR027105", "name" : "Prp31", "description" : "U4/U6 small nuclear ribonucleoprotein Prp31", "type" : "FAMILY", "goXRefs" : [ { "name" : "spliceosomal tri-snRNP complex assembly", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0000244" }, { "name" : "mRNA splicing, via spliceosome", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0000398" }, { "name" : "U4/U6 x U5 tri-snRNP complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0046540" } ], "pathwayXRefs" : [ { "name" : "mRNA Splicing - Major Pathway", "databaseName" : "Reactome", "id" : "R-HSA-72163" } ] } }, "locations" : [ { "start" : 1, "end" : 489, "hmmStart" : 1, "hmmEnd" : 490, "hmmLength" : 491, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 491, "location-fragments" : [ { "start" : 1, "end" : 489, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.1E-194, "familyName" : "PRE-MRNA SPLICING FACTOR PRP31", "score" : 647.5, "model-ac" : "PTHR13904" } ], "xref" : [ { "name" : "XP_018909599.1 PREDICTED: U4/U6 small nuclear ribonucleoprotein Prp31 [Bemisia tabaci]", "id" : "XP_018909599.1" } ] },{ "sequence" : "MEEEILKMPRVFSTAASRHLIPRLSFYATIGLFLLCLVPIDTSATGQPLERLVLPHKSGRELRFNKNGEFKILQVADMHYADGILTPCLDVDEEQALTCTDLNTTAFIERLIQNEKPDLIVFTGDNIYGNDSSDPEKSLNAAFAPAIVAGIPWAAVLGNHDDEGSLSKKMIMEQIAGMDYSVSRVNPPGESAIDGFGNYNLEVGGVKGSTFENKSVLNLYFLDSGSYSTNPIIQGYDWVKLSQQLWFRRISAELQEAYKKEPEPQELSAPALAYFHIPLPEFGQVNNSEGTKFENISSASVNSGLFTTMAEAGDVKAIFTGHDHLNDFCGDLYEMHLCYAGGVGYHAYGMAGWPRRSRVVLATLEKTEDGSWGGVRTIRTWKRLDDPDFSKIDEQTLWSKFDEPPATEQPLVNLEKAFDNC", "md5" : "7441e491d2464f9f7a3e4e060491ee9d", "matches" : [ { "signature" : { "accession" : "PIRSF030250", "name" : "Ptase_At2g46880", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR011230", "name" : "Pesterase_At2g46", "description" : "Phosphoesterase At2g46880", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 21, "end" : 398, "hmmStart" : 54, "hmmEnd" : 398, "hmmLength" : 355, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.2E-112, "score" : 372.2, "envelopeStart" : 21, "envelopeEnd" : 398, "postProcessed" : false, "location-fragments" : [ { "start" : 21, "end" : 398, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.8E-113, "score" : 372.4, "model-ac" : "PIRSF030250" }, { "signature" : { "accession" : "cd07383", "name" : "MPP_Dcr2", "description" : "MPP_Dcr2", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 68, "end" : 349, "sites" : [ { "description" : "putative metal binding site", "numLocations" : 7, "siteLocations" : [ { "start" : 276, "end" : 276, "residue" : "H" }, { "start" : 324, "end" : 324, "residue" : "H" }, { "start" : 322, "end" : 322, "residue" : "H" }, { "start" : 79, "end" : 79, "residue" : "H" }, { "start" : 159, "end" : 159, "residue" : "N" }, { "start" : 77, "end" : 77, "residue" : "D" }, { "start" : 125, "end" : 125, "residue" : "D" } ] }, { "description" : "putative active site", "numLocations" : 8, "siteLocations" : [ { "start" : 276, "end" : 276, "residue" : "H" }, { "start" : 324, "end" : 324, "residue" : "H" }, { "start" : 322, "end" : 322, "residue" : "H" }, { "start" : 79, "end" : 79, "residue" : "H" }, { "start" : 160, "end" : 160, "residue" : "H" }, { "start" : 159, "end" : 159, "residue" : "N" }, { "start" : 77, "end" : 77, "residue" : "D" }, { "start" : 125, "end" : 125, "residue" : "D" } ] } ], "evalue" : 8.98824E-69, "score" : 214.849, "location-fragments" : [ { "start" : 68, "end" : 349, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd07383" }, { "signature" : { "accession" : "PTHR32440:SF23", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 60, "end" : 400, "hmmStart" : 32, "hmmEnd" : 375, "hmmLength" : 379, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 50, "envelopeEnd" : 403, "location-fragments" : [ { "start" : 60, "end" : 400, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-147, "familyName" : "", "score" : 494.5, "model-ac" : "PTHR32440:SF23" }, { "signature" : { "accession" : "PF00149", "name" : "Metallophos", "description" : "Calcineurin-like phosphoesterase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004843", "name" : "Calcineurin-like_PHP_ApaH", "description" : "Calcineurin-like phosphoesterase domain, ApaH type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "hydrolase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016787" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 70, "end" : 325, "hmmStart" : 1, "hmmEnd" : 204, "hmmLength" : 205, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.3E-20, "score" : 74.0, "envelopeStart" : 70, "envelopeEnd" : 326, "postProcessed" : true, "location-fragments" : [ { "start" : 70, "end" : 325, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-20, "score" : 74.5, "model-ac" : "PF00149" }, { "signature" : { "accession" : "PTHR32440", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 60, "end" : 400, "hmmStart" : 32, "hmmEnd" : 375, "hmmLength" : 379, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 50, "envelopeEnd" : 403, "location-fragments" : [ { "start" : 60, "end" : 400, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-147, "familyName" : "", "score" : 494.5, "model-ac" : "PTHR32440" }, { "signature" : { "accession" : "G3DSA:3.60.21.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029052", "name" : "Metallo-depent_PP-like", "description" : "Metallo-dependent phosphatase-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 69, "end" : 371, "hmmStart" : 4, "hmmEnd" : 231, "hmmLength" : 266, "hmmBounds" : "COMPLETE", "evalue" : 4.7E-17, "score" : 64.5, "envelopeStart" : 69, "envelopeEnd" : 371, "postProcessed" : true, "location-fragments" : [ { "start" : 69, "end" : 371, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-17, "score" : 65.0, "model-ac" : "4nzvA01" }, { "signature" : { "accession" : "SSF56300", "name" : "Metallo-dependent phosphatases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 68, "end" : 373, "hmmLength" : 300, "location-fragments" : [ { "start" : 68, "end" : 373, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.06E-43, "model-ac" : "0048962" } ], "xref" : [ { "name" : "XP_018910520.1 PREDICTED: probable inactive purple acid phosphatase 29 [Bemisia tabaci]", "id" : "XP_018910520.1" }, { "name" : "XP_018910521.1 PREDICTED: probable inactive purple acid phosphatase 29 [Bemisia tabaci]", "id" : "XP_018910521.1" } ] },{ "sequence" : "MYEERYRYNSRHYNFLQPSQINGMTLKYFGIPNICGEVSRHFLSSHSDLDKLLKNAKKRQNKRTAEKKREFHRTFQNFVPDFGFDKEQEGAREEEFMAECSTLTQQSDDSDDWMSSSVSTKLRPDDDSSKRTAENGMNAPKIFPSFSYRQHRESQKTLPMRNQHLPQNVTQDTCNNHLLNNVSEKTTNKQKARGGVLKTLYSSPQSIDSVSEVETVSKTCNQDFDVAQTQASSSTLLTEDEGLHKYRKQLRKIGGQQNHTSQNQEFQKPLHPAPIKRKSSIKINAKRGDHLQPFATNSSTGRNILTEKFDENELVVDKKVVTTNFRKTVHFQEDTFEPKAEETMCELSRMQIKETGKIHQQIKNKDENIQPQIRKIVQNIPPPTEDTDFDKKALNTDLKGNCLKQSANNREFNDWATITTEEDSSDASNSSSEDVNKVDKTIQLPQFGIDILSDLQTTETNSQNIKYSATSGANEQCNLNFTAPQDHSSTVENQNSQECYETRQAPKFDGAIAGMARGNETSSIVMSETDDDMASDLNYDVNLPGGQDTYILESDVRRMTRNMPISVSDHKVADTVKNNKTGSTIMSESSDDTESELSCNINNISRTNGRILSESSDLSSPATDSSSSLDSSSIIDTSQNMMAKCDNKDGNLPGGQATYILESDVRGMTRNMPISVSDHKVADTVKNNKTGSNVMSESGDDTKSELSYNINKVPRTNGRILSESSDLSSPATDSSSSIDSTTIIDTSQNTVAKCDNKNGNTTSVQTEQINSQHALRGVDQYTVTFQILDAKNEDHRPLEENSTFKRDDSRLENALIPDMQRQELTLHDPFEAERVKRSPTEEKSPTSTSSPDSSLMVTKFKALEPPSNLYETQSTLVSESDESSVPDQIISSSSEGSTIKLMSDDSKSLTSEEGIIPRPLSEKSTLLRATNLPSNFPKTRDFSIFQQGPPNLPSFPEQDQKNCSPIRNLTKPKAPEEQTESDGSQTTSVSTSNQSSALDQSVTDEGRDINRQRDTIQSIVPHTDITFKGKPGERTPRHGLIGYSSSNSDESDIGSISFMTAKQSRGADLKMKTSSLQVDRSKFKDSLDSMSSENIITDFSLNESSSDYQTPKRKFEFENVHDLTVPQNRRVKREGASSSSTTSSEQILSNFSLLQRATSTPDQTTRGQKTSEDINDQTPPSSILSSLNKMLGIESSTLMSKKKNVDRNGTHLAGFESTLSPVVSEKSFFKSLGAETDFEDFDNVINSQISREALNSHHSERNAQINKTVQQNKKKFEVFSPETESSSSSKGSENWHNSSTTLVEKEQRTFDASEKDASSDDRESISSFVSSITDQARVSKLQQTAKQDDPFEKFYEKNYQKLKMDALEEHRDEDNVRKNFEMLSVETESSSSSKGSENWHNSSTTLVEKEQRTFDASDKDASSDDRESISSFVSSITDQARVSKLQQTAKQDDPFEKFYEKNYQKLKMDALEEHRDEDNVIKLYENLRKGFSSGYTNSAANIPRHNIQEEEENSLFSLSDSTETKQLKKRKYSTNKNIINDGQFKGIKKNSHRHPMDCEPAGTSKIVKEKDSDELVFADVKSPIDTSNSTSTGSSNMQDIFSPEHFKELKNEFSNKDAITKLYEKEKTRHFSSSSSSLKNSQSLSSLTFSDDSKSQKRKRVRRRPLRERNTSFKREDTSSGTN", "md5" : "1687068275c4696b7dd672199cc5d1fe", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 612, "end" : 635, "location-fragments" : [ { "start" : 612, "end" : 635, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1150, "end" : 1182, "location-fragments" : [ { "start" : 1150, "end" : 1182, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 414, "end" : 434, "location-fragments" : [ { "start" : 414, "end" : 434, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 867, "end" : 910, "location-fragments" : [ { "start" : 867, "end" : 910, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1252, "end" : 1306, "location-fragments" : [ { "start" : 1252, "end" : 1306, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 979, "end" : 1003, "location-fragments" : [ { "start" : 979, "end" : 1003, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 247, "end" : 276, "location-fragments" : [ { "start" : 247, "end" : 276, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1307, "end" : 1322, "location-fragments" : [ { "start" : 1307, "end" : 1322, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1624, "end" : 1683, "location-fragments" : [ { "start" : 1624, "end" : 1683, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 253, "end" : 268, "location-fragments" : [ { "start" : 253, "end" : 268, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 938, "end" : 1015, "location-fragments" : [ { "start" : 938, "end" : 1015, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 842, "end" : 856, "location-fragments" : [ { "start" : 842, "end" : 856, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1368, "end" : 1432, "location-fragments" : [ { "start" : 1368, "end" : 1432, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 107, "end" : 122, "location-fragments" : [ { "start" : 107, "end" : 122, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1580, "end" : 1603, "location-fragments" : [ { "start" : 1580, "end" : 1603, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1411, "end" : 1426, "location-fragments" : [ { "start" : 1411, "end" : 1426, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 107, "end" : 137, "location-fragments" : [ { "start" : 107, "end" : 137, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1252, "end" : 1328, "location-fragments" : [ { "start" : 1252, "end" : 1328, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 938, "end" : 967, "location-fragments" : [ { "start" : 938, "end" : 967, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1382, "end" : 1410, "location-fragments" : [ { "start" : 1382, "end" : 1410, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 815, "end" : 917, "location-fragments" : [ { "start" : 815, "end" : 917, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1582, "end" : 1601, "location-fragments" : [ { "start" : 1582, "end" : 1601, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 824, "end" : 841, "location-fragments" : [ { "start" : 824, "end" : 841, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1633, "end" : 1651, "location-fragments" : [ { "start" : 1633, "end" : 1651, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 715, "end" : 741, "location-fragments" : [ { "start" : 715, "end" : 741, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910033.1 PREDICTED: uncharacterized protein LOC109039131 [Bemisia tabaci]", "id" : "XP_018910033.1" } ] },{ "sequence" : "MMAGSSRFDANTVCCPSHPDANLIEDYRAGDQICEECGLVVGDRVIDVGSEWRTFSNEKSGVDPSRVGGPENPLLGGGDLSTIIGPGRGSASYDEMGVSIYHNRRSMSTSDRALIGAFKEINAMADRINLPKTIVDRANNLFKQVHEGKNLKGRANDAIASACLYIACRQEGVPRTFKEICAVSKISKKEIGRCFKSILKALETSVDLITTGDFMSRFCSNLALPNMVQKAATHIARKAVELDVVSGRSPISVAAAAIYMASQASEDKRTQKEIGDIAGVADVTIRQSYKLMYPHAAKLFPDDFKFATPIEQLPQM", "md5" : "db1cdac4b1a9f181f6226862286fc550", "matches" : [ { "signature" : { "accession" : "PTHR11618:SF13", "name" : "TRANSCRIPTION INITIATION FACTOR IIB", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 311, "hmmStart" : 7, "hmmEnd" : 310, "hmmLength" : 312, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 313, "location-fragments" : [ { "start" : 10, "end" : 311, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-116, "familyName" : "TRANSCRIPTION INITIATION FACTOR IIB", "score" : 391.1, "model-ac" : "PTHR11618:SF13" }, { "signature" : { "accession" : "cd00043", "name" : "CYCLIN", "description" : "CYCLIN", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR013763", "name" : "Cyclin-like", "description" : "Cyclin-like", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 117, "end" : 199, "sites" : [ { "description" : "binding site 2", "numLocations" : 6, "siteLocations" : [ { "start" : 191, "end" : 191, "residue" : "I" }, { "start" : 165, "end" : 165, "residue" : "Y" }, { "start" : 169, "end" : 169, "residue" : "R" }, { "start" : 194, "end" : 194, "residue" : "C" }, { "start" : 195, "end" : 195, "residue" : "F" }, { "start" : 176, "end" : 176, "residue" : "T" } ] } ], "evalue" : 4.49036E-15, "score" : 67.6488, "location-fragments" : [ { "start" : 117, "end" : 199, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00043" }, { "signature" : { "accession" : "PS00782", "name" : "TFIIB", "description" : "Transcription factor TFIIB repeat signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR023486", "name" : "TFIIB_CS", "description" : "Transcription factor TFIIB, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "RNA Polymerase II Promoter Escape", "databaseName" : "Reactome", "id" : "R-HSA-73776" }, { "name" : "RNA Polymerase II HIV Promoter Escape", "databaseName" : "Reactome", "id" : "R-HSA-167162" }, { "name" : "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening", "databaseName" : "Reactome", "id" : "R-HSA-73779" }, { "name" : "RNA Polymerase II Pre-transcription Events", "databaseName" : "Reactome", "id" : "R-HSA-674695" }, { "name" : "Transcription of the HIV genome", "databaseName" : "Reactome", "id" : "R-HSA-167172" }, { "name" : "RNA Polymerase II Transcription Initiation", "databaseName" : "Reactome", "id" : "R-HSA-75953" }, { "name" : "HIV Transcription Initiation", "databaseName" : "Reactome", "id" : "R-HSA-167161" }, { "name" : "RNA polymerase II transcribes snRNA genes", "databaseName" : "Reactome", "id" : "R-HSA-6807505" }, { "name" : "RNA Polymerase II Transcription Initiation And Promoter Clearance", "databaseName" : "Reactome", "id" : "R-HSA-76042" } ] } }, "locations" : [ { "start" : 247, "end" : 262, "level" : "STRONG", "cigarAlignment" : "2M3I11M", "alignment" : "GRspiSVAAAAIYMAS", "location-fragments" : [ { "start" : 247, "end" : 262, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00782" }, { "signature" : { "accession" : "G3DSA:2.20.25.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 59, "hmmStart" : 8, "hmmEnd" : 57, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 6.3E-26, "score" : 91.7, "envelopeStart" : 3, "envelopeEnd" : 59, "postProcessed" : true, "location-fragments" : [ { "start" : 3, "end" : 59, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-26, "score" : 92.5, "model-ac" : "1dl6A00" }, { "signature" : { "accession" : "PTHR11618", "name" : "TRANSCRIPTION INITIATION FACTOR IIB-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR000812", "name" : "TFIIB", "description" : "Transcription factor TFIIB", "type" : "FAMILY", "goXRefs" : [ { "name" : "transcription preinitiation complex assembly", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0070897" }, { "name" : "DNA-templated transcription, initiation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006352" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 311, "hmmStart" : 7, "hmmEnd" : 310, "hmmLength" : 312, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 313, "location-fragments" : [ { "start" : 10, "end" : 311, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-116, "familyName" : "TRANSCRIPTION INITIATION FACTOR IIB", "score" : 391.1, "model-ac" : "PTHR11618" }, { "signature" : { "accession" : "PS51134", "name" : "ZF_TFIIB", "description" : "Zinc finger TFIIB-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013137", "name" : "Znf_TFIIB", "description" : "Zinc finger, TFIIB-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 11, "end" : 42, "score" : 9.439, "alignment" : "NTVCCPSHPDANLIEDYRAGDQICEECGLVVG", "location-fragments" : [ { "start" : 11, "end" : 42, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51134" }, { "signature" : { "accession" : "PR00685", "name" : "TIFACTORIIB", "description" : "Transcription initiation factor IIB signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000812", "name" : "TFIIB", "description" : "Transcription factor TFIIB", "type" : "FAMILY", "goXRefs" : [ { "name" : "transcription preinitiation complex assembly", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0070897" }, { "name" : "DNA-templated transcription, initiation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006352" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 49, "end" : 62, "pvalue" : 1.36E-5, "score" : 56.67, "motifNumber" : 2, "location-fragments" : [ { "start" : 49, "end" : 62, "dc-status" : "CONTINUOUS" } ] }, { "start" : 63, "end" : 84, "pvalue" : 1.17E-14, "score" : 60.0, "motifNumber" : 3, "location-fragments" : [ { "start" : 63, "end" : 84, "dc-status" : "CONTINUOUS" } ] }, { "start" : 214, "end" : 232, "pvalue" : 2.29E-11, "score" : 54.39, "motifNumber" : 6, "location-fragments" : [ { "start" : 214, "end" : 232, "dc-status" : "CONTINUOUS" } ] }, { "start" : 161, "end" : 180, "pvalue" : 4.78E-13, "score" : 72.0, "motifNumber" : 4, "location-fragments" : [ { "start" : 161, "end" : 180, "dc-status" : "CONTINUOUS" } ] }, { "start" : 248, "end" : 264, "pvalue" : 8.79E-11, "score" : 68.24, "motifNumber" : 7, "location-fragments" : [ { "start" : 248, "end" : 264, "dc-status" : "CONTINUOUS" } ] }, { "start" : 187, "end" : 202, "pvalue" : 2.96E-9, "score" : 57.92, "motifNumber" : 5, "location-fragments" : [ { "start" : 187, "end" : 202, "dc-status" : "CONTINUOUS" } ] }, { "start" : 27, "end" : 47, "pvalue" : 1.5E-11, "score" : 56.51, "motifNumber" : 1, "location-fragments" : [ { "start" : 27, "end" : 47, "dc-status" : "CONTINUOUS" } ] }, { "start" : 280, "end" : 294, "pvalue" : 3.32E-8, "score" : 58.67, "motifNumber" : 8, "location-fragments" : [ { "start" : 280, "end" : 294, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-73, "graphscan" : "IIIIIIII", "model-ac" : "PR00685" }, { "signature" : { "accession" : "SSF47954", "name" : "Cyclin-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036915", "name" : "Cyclin-like_sf", "description" : "Cyclin-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 209, "end" : 315, "hmmLength" : 109, "location-fragments" : [ { "start" : 209, "end" : 315, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.38E-33, "model-ac" : "0044902" }, { "signature" : { "accession" : "SSF57783", "name" : "Zinc beta-ribbon", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 58, "hmmLength" : 58, "location-fragments" : [ { "start" : 11, "end" : 58, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-15, "model-ac" : "0046355" }, { "signature" : { "accession" : "PF00382", "name" : "TFIIB", "description" : "Transcription factor TFIIB repeat", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013150", "name" : "TFIIB_cyclin", "description" : "Transcription factor TFIIB, cyclin-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "TBP-class protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0017025" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 121, "end" : 191, "hmmStart" : 1, "hmmEnd" : 71, "hmmLength" : 71, "hmmBounds" : "COMPLETE", "evalue" : 3.6E-27, "score" : 94.2, "envelopeStart" : 121, "envelopeEnd" : 191, "postProcessed" : true, "location-fragments" : [ { "start" : 121, "end" : 191, "dc-status" : "CONTINUOUS" } ] }, { "start" : 215, "end" : 285, "hmmStart" : 1, "hmmEnd" : 71, "hmmLength" : 71, "hmmBounds" : "COMPLETE", "evalue" : 3.4E-25, "score" : 87.9, "envelopeStart" : 215, "envelopeEnd" : 285, "postProcessed" : true, "location-fragments" : [ { "start" : 215, "end" : 285, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-54, "score" : 180.0, "model-ac" : "PF00382" }, { "signature" : { "accession" : "SM00385", "name" : "cyclin_7", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR013763", "name" : "Cyclin-like", "description" : "Cyclin-like", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 213, "end" : 294, "hmmStart" : 1, "hmmEnd" : 90, "hmmLength" : 90, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-9, "score" : 48.2, "location-fragments" : [ { "start" : 213, "end" : 294, "dc-status" : "CONTINUOUS" } ] }, { "start" : 119, "end" : 200, "hmmStart" : 1, "hmmEnd" : 90, "hmmLength" : 90, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-12, "score" : 57.2, "location-fragments" : [ { "start" : 119, "end" : 200, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-27, "score" : 105.4, "model-ac" : "SM00385" }, { "signature" : { "accession" : "cd00043", "name" : "CYCLIN", "description" : "CYCLIN", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR013763", "name" : "Cyclin-like", "description" : "Cyclin-like", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 213, "end" : 293, "sites" : [ { "description" : "binding site 2", "numLocations" : 6, "siteLocations" : [ { "start" : 270, "end" : 270, "residue" : "T" }, { "start" : 285, "end" : 285, "residue" : "I" }, { "start" : 259, "end" : 259, "residue" : "Y" }, { "start" : 263, "end" : 263, "residue" : "Q" }, { "start" : 288, "end" : 288, "residue" : "S" }, { "start" : 289, "end" : 289, "residue" : "Y" } ] } ], "evalue" : 1.30666E-14, "score" : 66.108, "location-fragments" : [ { "start" : 213, "end" : 293, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00043" }, { "signature" : { "accession" : "PF08271", "name" : "TF_Zn_Ribbon", "description" : "TFIIB zinc-binding", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013137", "name" : "Znf_TFIIB", "description" : "Zinc finger, TFIIB-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 15, "end" : 55, "hmmStart" : 3, "hmmEnd" : 43, "hmmLength" : 43, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.5E-12, "score" : 44.6, "envelopeStart" : 13, "envelopeEnd" : 55, "postProcessed" : true, "location-fragments" : [ { "start" : 15, "end" : 55, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-12, "score" : 45.2, "model-ac" : "PF08271" }, { "signature" : { "accession" : "G3DSA:1.10.472.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 113, "end" : 209, "hmmStart" : 2, "hmmEnd" : 97, "hmmLength" : 97, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-41, "score" : 142.3, "envelopeStart" : 113, "envelopeEnd" : 209, "postProcessed" : true, "location-fragments" : [ { "start" : 113, "end" : 209, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-60, "score" : 200.8, "model-ac" : "1c9bA01" }, { "signature" : { "accession" : "SSF47954", "name" : "Cyclin-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036915", "name" : "Cyclin-like_sf", "description" : "Cyclin-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 116, "end" : 207, "hmmLength" : 95, "location-fragments" : [ { "start" : 116, "end" : 207, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.06E-27, "model-ac" : "0045780" }, { "signature" : { "accession" : "PS00782", "name" : "TFIIB", "description" : "Transcription factor TFIIB repeat signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR023486", "name" : "TFIIB_CS", "description" : "Transcription factor TFIIB, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "RNA Polymerase II Promoter Escape", "databaseName" : "Reactome", "id" : "R-HSA-73776" }, { "name" : "RNA Polymerase II HIV Promoter Escape", "databaseName" : "Reactome", "id" : "R-HSA-167162" }, { "name" : "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening", "databaseName" : "Reactome", "id" : "R-HSA-73779" }, { "name" : "RNA Polymerase II Pre-transcription Events", "databaseName" : "Reactome", "id" : "R-HSA-674695" }, { "name" : "Transcription of the HIV genome", "databaseName" : "Reactome", "id" : "R-HSA-167172" }, { "name" : "RNA Polymerase II Transcription Initiation", "databaseName" : "Reactome", "id" : "R-HSA-75953" }, { "name" : "HIV Transcription Initiation", "databaseName" : "Reactome", "id" : "R-HSA-167161" }, { "name" : "RNA polymerase II transcribes snRNA genes", "databaseName" : "Reactome", "id" : "R-HSA-6807505" }, { "name" : "RNA Polymerase II Transcription Initiation And Promoter Clearance", "databaseName" : "Reactome", "id" : "R-HSA-76042" } ] } }, "locations" : [ { "start" : 153, "end" : 168, "level" : "STRONG", "cigarAlignment" : "2M3I11M", "alignment" : "GRandAIASACLYIAC", "location-fragments" : [ { "start" : 153, "end" : 168, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00782" }, { "signature" : { "accession" : "G3DSA:1.10.472.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 210, "end" : 315, "hmmStart" : 3, "hmmEnd" : 105, "hmmLength" : 106, "hmmBounds" : "COMPLETE", "evalue" : 4.1E-35, "score" : 122.0, "envelopeStart" : 210, "envelopeEnd" : 315, "postProcessed" : true, "location-fragments" : [ { "start" : 210, "end" : 315, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-65, "score" : 217.8, "model-ac" : "1c9bA02" } ], "xref" : [ { "name" : "XP_018910089.1 PREDICTED: transcription initiation factor IIB [Bemisia tabaci]", "id" : "XP_018910089.1" } ] },{ "sequence" : "MDACSHLKEQYDTCFNTWFTQKFLKGDYDDEMCAPLLKVYTQCVKKAMKEEKLDFKEFEEDILGTEKEYKPPPPK", "md5" : "6e5c687e8284d4f7dcb40ef146f08de8", "matches" : [ { "signature" : { "accession" : "PF05254", "name" : "UPF0203", "description" : "Uncharacterised protein family (UPF0203)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR007918", "name" : "MDM35_apoptosis", "description" : "Mitochondrial distribution/morphology family 35/apoptosis", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release", "databaseName" : "Reactome", "id" : "R-HSA-6803204" } ] } }, "locations" : [ { "start" : 2, "end" : 55, "hmmStart" : 5, "hmmEnd" : 60, "hmmLength" : 69, "hmmBounds" : "INCOMPLETE", "evalue" : 6.5E-19, "score" : 67.9, "envelopeStart" : 1, "envelopeEnd" : 63, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 55, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-19, "score" : 68.2, "model-ac" : "PF05254" }, { "signature" : { "accession" : "PS51808", "name" : "CHCH", "description" : "Coiled coil-helix-coiled coil-helix (CHCH) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 51, "score" : 11.333, "alignment" : "MDACSHLKEQYDTCFNTWFTQKFlkgdyddeMCAPLLKVYTQCVKKAMKEE", "location-fragments" : [ { "start" : 1, "end" : 51, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51808" }, { "signature" : { "accession" : "PTHR46403", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 68, "hmmStart" : 25, "hmmEnd" : 93, "hmmLength" : 106, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 75, "location-fragments" : [ { "start" : 2, "end" : 68, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-19, "familyName" : "FAMILY NOT NAMED", "score" : 72.9, "model-ac" : "PTHR46403" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 48, "end" : 68, "location-fragments" : [ { "start" : 48, "end" : 68, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" } ], "xref" : [ { "name" : "XP_018909736.1 PREDICTED: TP53-regulated inhibitor of apoptosis 1-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909736.1" } ] },{ "sequence" : "MLHVTKKWELFPGRNQFCCDGRIIMAPNATVFYINVLLIVGTTSLFFIFDCPYLAMKITPLIPVIAAVMFSFVMFVLLRTSFSDPGIIPRATPDEAAYIEKLFEIPNNPNSPTHRPPPRTKEILIKGQTVKLKYCSTCKIFRPPRASHCSICDNCVEHFDHHCPWVGNCVGKRNYRYFYMFTISLAFHIVFVFGCTMTHLILLSDGKLFITAISESPASLIVLVVSFFSVWTVLGLAGFHTYLAASNQTTNEDIKGSFTSKRERSNFNPYSNGNVCSNCCFVLCGPVPPSLIDRRGIVTAEYEADRITISSTKLPELQPAHTSTIDRYSSQADVYRSRDGDSKVISKSPSEDQIMMSTSEKPYDGKMVDAGSMYPPVTPRMSGGACHQKAVEVPKVISIDTPINDIYLERYNQSKNPEGQSTVLPLSSIYSSPTHMNPPSTFLNTSPSLGNPASTLPSRSFNTSMTTIPLNEFPVSSPATLPSGEEILLNPLDYVALSSQSKKEPNNYLSTSLSVIAPTLQNKRPQFSNNTSFQSKAGLVDCNLGNDMSTNPCCNPPIDITNMDLDLDDVIIPNSHMDHFDDKDSPWLSSNQPLSASRLRLLQDTTMIESALDLDSLEESTSSVGASSLHGLLHKTKDNSSS", "md5" : "74826eb3963fcb3c824182dcb402f8c7", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 332, "end" : 346, "location-fragments" : [ { "start" : 332, "end" : 346, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF01529", "name" : "DHHC", "description" : "DHHC palmitoyltransferase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001594", "name" : "Palmitoyltrfase_DHHC", "description" : "Palmitoyltransferase, DHHC domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "palmitoyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016409" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 131, "end" : 255, "hmmStart" : 4, "hmmEnd" : 132, "hmmLength" : 134, "hmmBounds" : "INCOMPLETE", "evalue" : 8.7E-37, "score" : 126.2, "envelopeStart" : 128, "envelopeEnd" : 257, "postProcessed" : true, "location-fragments" : [ { "start" : 131, "end" : 255, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.7E-37, "score" : 126.2, "model-ac" : "PF01529" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 321, "end" : 356, "location-fragments" : [ { "start" : 321, "end" : 356, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR22883:SF71", "name" : "PALMITOYLTRANSFERASE ZDHHC9", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 335, "hmmStart" : 9, "hmmEnd" : 338, "hmmLength" : 362, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 359, "location-fragments" : [ { "start" : 3, "end" : 335, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-142, "familyName" : "PALMITOYLTRANSFERASE ZDHHC9", "score" : 477.6, "model-ac" : "PTHR22883:SF71" }, { "signature" : { "accession" : "PTHR22883", "name" : "ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 335, "hmmStart" : 9, "hmmEnd" : 338, "hmmLength" : 362, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 359, "location-fragments" : [ { "start" : 3, "end" : 335, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-142, "familyName" : "PALMITOYLTRANSFERASE ZDHHC9", "score" : 477.6, "model-ac" : "PTHR22883" }, { "signature" : { "accession" : "PS50216", "name" : "DHHC", "description" : "DHHC domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 133, "end" : 183, "score" : 27.789, "alignment" : "KYCSTCKIFRPPRASHCSICDNCVEHFDHHCPWVGNCVGKRNYRYFYMFTI", "location-fragments" : [ { "start" : 133, "end" : 183, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50216" } ], "xref" : [ { "name" : "XP_018909985.1 PREDICTED: palmitoyltransferase ZDHHC9 [Bemisia tabaci]", "id" : "XP_018909985.1" } ] },{ "sequence" : "MVEGNRIELTEDEAELYDRQIRLWGLESQKRLRAAKVLVIGMSGLGAEVTKNIVLAGVKSLTMMDGSVATKEDLCSQFFIPHSELGKNRAEASVERAQQLNPMVEVKAVPHYPEKFADEPDFFTKFDIVCATRLDLPTYLKINTICRNANVKFFCADVFGTFGYHFSDLQNHEYAEEETKQIAKPVMSSHTPNKRAKMEKEAVKVTVKKTDNFVPLQAVVDMDWKNEENKKKLNEMDSSFFLSMILLSFRSKQKRDPSPATREEDIKLLQSIRDEFLTDKSVPLEKVPDECFRTVFAEVSPSCAVVGGVLAQEIIKVVSQKGAPHNNLFFFNPLSSCGTVVSLGNTPSQNSKQEPVDLIDLDDD", "md5" : "7e97c8ef0c6bb81e052889debffcba7d", "matches" : [ { "signature" : { "accession" : "G3DSA:3.40.50.720", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 346, "hmmStart" : 10, "hmmEnd" : 344, "hmmLength" : 346, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-119, "score" : 401.5, "envelopeStart" : 3, "envelopeEnd" : 346, "postProcessed" : true, "location-fragments" : [ { "start" : 3, "end" : 346, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.7E-120, "score" : 401.8, "model-ac" : "1y8qC00" }, { "signature" : { "accession" : "PTHR10953:SF201", "name" : "SUMO-ACTIVATING ENZYME SUBUNIT 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 345, "hmmStart" : 12, "hmmEnd" : 345, "hmmLength" : 346, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 346, "location-fragments" : [ { "start" : 10, "end" : 345, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.0E-89, "familyName" : "SUMO-ACTIVATING ENZYME SUBUNIT 1", "score" : 301.0, "model-ac" : "PTHR10953:SF201" }, { "signature" : { "accession" : "PTHR10953", "name" : "UBIQUITIN-ACTIVATING ENZYME E1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 10, "end" : 345, "hmmStart" : 12, "hmmEnd" : 345, "hmmLength" : 346, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 346, "location-fragments" : [ { "start" : 10, "end" : 345, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.0E-89, "familyName" : "SUMO-ACTIVATING ENZYME SUBUNIT 1", "score" : 301.0, "model-ac" : "PTHR10953" }, { "signature" : { "accession" : "PR01849", "name" : "UBIQUITINACT", "description" : "Ubiquitin-activating enzyme E1 signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000011", "name" : "UBQ/SUMO-activ_enz_E1-like", "description" : "Ubiquitin/SUMO-activating enzyme E1", "type" : "FAMILY", "goXRefs" : [ { "name" : "ubiquitin-like modifier activating enzyme activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008641" }, { "name" : "cellular protein modification process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006464" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 156, "end" : 183, "pvalue" : 0.0656, "score" : 23.36, "motifNumber" : 2, "location-fragments" : [ { "start" : 156, "end" : 183, "dc-status" : "CONTINUOUS" } ] }, { "start" : 38, "end" : 62, "pvalue" : 3.33E-16, "score" : 62.67, "motifNumber" : 1, "location-fragments" : [ { "start" : 38, "end" : 62, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-11, "graphscan" : "Ii...", "model-ac" : "PR01849" }, { "signature" : { "accession" : "PF00899", "name" : "ThiF", "description" : "ThiF family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000594", "name" : "ThiF_NAD_FAD-bd", "description" : "THIF-type NAD/FAD binding fold", "type" : "DOMAIN", "goXRefs" : [ { "name" : "ubiquitin-like modifier activating enzyme activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008641" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 17, "end" : 345, "hmmStart" : 1, "hmmEnd" : 236, "hmmLength" : 244, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.4E-37, "score" : 128.1, "envelopeStart" : 17, "envelopeEnd" : 353, "postProcessed" : true, "location-fragments" : [ { "start" : 17, "end" : 345, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-37, "score" : 128.6, "model-ac" : "PF00899" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 345, "end" : 364, "location-fragments" : [ { "start" : 345, "end" : 364, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF69572", "name" : "Activating enzymes of the ubiquitin-like proteins", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035985", "name" : "Ubiquitin-activating_enz", "description" : "Ubiquitin-activating enzyme", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "ubiquitin-like modifier activating enzyme activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008641" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 340, "hmmLength" : 529, "location-fragments" : [ { "start" : 10, "end" : 340, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-74, "model-ac" : "0051359" }, { "signature" : { "accession" : "cd01492", "name" : "Aos1_SUMO", "description" : "Aos1_SUMO", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 341, "sites" : [ { "description" : "dimer interaction", "numLocations" : 28, "siteLocations" : [ { "start" : 26, "end" : 26, "residue" : "L" }, { "start" : 312, "end" : 312, "residue" : "Q" }, { "start" : 96, "end" : 96, "residue" : "R" }, { "start" : 99, "end" : 99, "residue" : "Q" }, { "start" : 71, "end" : 71, "residue" : "K" }, { "start" : 16, "end" : 16, "residue" : "L" }, { "start" : 22, "end" : 22, "residue" : "R" }, { "start" : 334, "end" : 334, "residue" : "L" }, { "start" : 100, "end" : 100, "residue" : "L" }, { "start" : 52, "end" : 52, "residue" : "N" }, { "start" : 308, "end" : 308, "residue" : "G" }, { "start" : 76, "end" : 76, "residue" : "S" }, { "start" : 51, "end" : 51, "residue" : "K" }, { "start" : 74, "end" : 74, "residue" : "L" }, { "start" : 78, "end" : 78, "residue" : "F" }, { "start" : 75, "end" : 75, "residue" : "C" }, { "start" : 304, "end" : 304, "residue" : "A" }, { "start" : 161, "end" : 161, "residue" : "T" }, { "start" : 85, "end" : 85, "residue" : "L" }, { "start" : 18, "end" : 18, "residue" : "D" }, { "start" : 24, "end" : 24, "residue" : "W" }, { "start" : 48, "end" : 48, "residue" : "E" }, { "start" : 23, "end" : 23, "residue" : "L" }, { "start" : 55, "end" : 55, "residue" : "L" }, { "start" : 19, "end" : 19, "residue" : "R" }, { "start" : 21, "end" : 21, "residue" : "I" }, { "start" : 20, "end" : 20, "residue" : "Q" }, { "start" : 72, "end" : 72, "residue" : "E" } ] } ], "evalue" : 5.29915E-80, "score" : 241.426, "location-fragments" : [ { "start" : 14, "end" : 341, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01492" } ], "xref" : [ { "name" : "XP_018910067.1 PREDICTED: SUMO-activating enzyme subunit 1 [Bemisia tabaci]", "id" : "XP_018910067.1" } ] },{ "sequence" : "MVSKHLKGHDTQQATVQSSGQRNRVNITLTGKEDLDRMEKQLRESAEYAEQVKMELLLLGGIDGRDLLIRILKKLLPPAVCNEMTLKGAMRKQVRKFKFMDSKIQTVIFGKCYLPIFTVGLNEFQMEE", "md5" : "0bfa667543ba8c1fba4be07db93cc2aa", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 35, "end" : 55, "location-fragments" : [ { "start" : 35, "end" : 55, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 23, "location-fragments" : [ { "start" : 1, "end" : 23, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910416.1 PREDICTED: uncharacterized protein LOC109039402 [Bemisia tabaci]", "id" : "XP_018910416.1" } ] },{ "sequence" : "MEYFDSVTRAYVSKIPLQESLTPRVQFQPFRFQCKQFMALWIKCNLKISNLFFLKQENVSYLLRSLENERGSMERTSNVLSRLSKKSSESNDVQLAWSSTESHPEWFQLSGHPDCFAVAGPGTIWKKCSDSTERDVYEALSKEPTLKNVIPRHLRTVEHDGQTFIELQDLLDGFEDPQVMDIKLGVRTFLESEVQNTTARQDLYKKMVAIDPDAPTEEEKQLQAVTKLRYMQFRENQSSTCSQGFRIEAIKLSGEPPRSNLQRVKSIEDVQNTLKLFLQEKEKARSQLVTILRNIRNKLEQTQYFKTHEVVGSSILIIHDNSKVGAWLIDFGKTRPVPDGLSVNHRTPWTPGNHEEGLLIGLDNLINIIENLKLKEVAVQDYD", "md5" : "3e43eb1d855c40d8efbbc0fad0624d11", "matches" : [ { "signature" : { "accession" : "PF03770", "name" : "IPK", "description" : "Inositol polyphosphate kinase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005522", "name" : "IPK", "description" : "Inositol polyphosphate kinase", "type" : "FAMILY", "goXRefs" : [ { "name" : "kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016301" }, { "name" : "inositol phosphate biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0032958" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 164, "end" : 370, "hmmStart" : 1, "hmmEnd" : 198, "hmmLength" : 198, "hmmBounds" : "COMPLETE", "evalue" : 6.7E-31, "score" : 107.7, "envelopeStart" : 164, "envelopeEnd" : 370, "postProcessed" : true, "location-fragments" : [ { "start" : 164, "end" : 370, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-31, "score" : 109.5, "model-ac" : "PF03770" }, { "signature" : { "accession" : "PTHR12400", "name" : "INOSITOL POLYPHOSPHATE KINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR005522", "name" : "IPK", "description" : "Inositol polyphosphate kinase", "type" : "FAMILY", "goXRefs" : [ { "name" : "kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016301" }, { "name" : "inositol phosphate biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0032958" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 104, "end" : 376, "hmmStart" : 77, "hmmEnd" : 350, "hmmLength" : 366, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 89, "envelopeEnd" : 382, "location-fragments" : [ { "start" : 104, "end" : 376, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-102, "familyName" : "KINASE", "score" : 345.9, "model-ac" : "PTHR12400" }, { "signature" : { "accession" : "PTHR12400:SF84", "name" : "KINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 104, "end" : 376, "hmmStart" : 77, "hmmEnd" : 350, "hmmLength" : 366, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 89, "envelopeEnd" : 382, "location-fragments" : [ { "start" : 104, "end" : 376, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-102, "familyName" : "KINASE", "score" : 345.9, "model-ac" : "PTHR12400:SF84" }, { "signature" : { "accession" : "G3DSA:1.10.510.50", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR038286", "name" : "IPK_sf", "description" : "Inositol polyphosphate kinase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 114, "end" : 374, "hmmStart" : 3, "hmmEnd" : 262, "hmmLength" : 265, "hmmBounds" : "COMPLETE", "evalue" : 3.6E-100, "score" : 336.5, "envelopeStart" : 114, "envelopeEnd" : 374, "postProcessed" : true, "location-fragments" : [ { "start" : 114, "end" : 374, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-100, "score" : 337.0, "model-ac" : "2aqxB01" }, { "signature" : { "accession" : "SSF56104", "name" : "SAICAR synthase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 105, "end" : 372, "hmmLength" : 276, "location-fragments" : [ { "start" : 105, "end" : 372, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.77E-72, "model-ac" : "0044935" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 267, "end" : 287, "location-fragments" : [ { "start" : 267, "end" : 287, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" } ], "xref" : [ { "name" : "XP_018910250.1 PREDICTED: inositol-trisphosphate 3-kinase A isoform X1 [Bemisia tabaci]", "id" : "XP_018910250.1" } ] },{ "sequence" : "MSIRGAFTPHEFRNLDKEKAWRLLEKGLAEMFGTGLFVCMGCMGTLSDSKGEYLDYLGGVLTFAFAIATSVMIFGHISCIINPALVAADVIRGEKSLFMFVYITVMECLGAFLGYALLRVLVADDLLGGTSGSFCCTAKDVRVTSLRAMGVEMLITAILCLLFCSVQDPKNSDRNSTVALKFGFGCFALLLPSVHYASSSMNPARSFGPALYNNHWKDQWIYWVGPMSGAIISAVIYMLLFAQHFPRSKREIRPNSHI", "md5" : "8a2b44770c7bddeb210f03ef58aa0847", "matches" : [ { "signature" : { "accession" : "G3DSA:1.20.1080.10", "name" : "Glycerol uptake facilitator protein.", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR023271", "name" : "Aquaporin-like", "description" : "Aquaporin-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Passive transport by Aquaporins", "databaseName" : "Reactome", "id" : "R-HSA-432047" } ] } }, "locations" : [ { "start" : 15, "end" : 253, "hmmStart" : 6, "hmmEnd" : 236, "hmmLength" : 249, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-52, "score" : 180.2, "envelopeStart" : 15, "envelopeEnd" : 253, "postProcessed" : true, "location-fragments" : [ { "start" : 15, "end" : 253, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-52, "score" : 180.5, "model-ac" : "1j4nA00" }, { "signature" : { "accession" : "PTHR19139", "name" : "AQUAPORIN TRANSPORTER", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR034294", "name" : "Aquaporin_transptr", "description" : "Aquaporin transporter", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Passive transport by Aquaporins", "databaseName" : "Reactome", "id" : "R-HSA-432047" } ] } }, "locations" : [ { "start" : 16, "end" : 251, "hmmStart" : 13, "hmmEnd" : 250, "hmmLength" : 263, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 257, "location-fragments" : [ { "start" : 16, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-63, "familyName" : "RT07464P", "score" : 215.5, "model-ac" : "PTHR19139" }, { "signature" : { "accession" : "SSF81338", "name" : "Aquaporin-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR023271", "name" : "Aquaporin-like", "description" : "Aquaporin-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Passive transport by Aquaporins", "databaseName" : "Reactome", "id" : "R-HSA-432047" } ] } }, "locations" : [ { "start" : 21, "end" : 248, "hmmLength" : 249, "location-fragments" : [ { "start" : 21, "end" : 248, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.49E-49, "model-ac" : "0039367" }, { "signature" : { "accession" : "PTHR19139:SF270", "name" : "RT07464P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 251, "hmmStart" : 13, "hmmEnd" : 250, "hmmLength" : 263, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 257, "location-fragments" : [ { "start" : 16, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-63, "familyName" : "RT07464P", "score" : 215.5, "model-ac" : "PTHR19139:SF270" }, { "signature" : { "accession" : "PF00230", "name" : "MIP", "description" : "Major intrinsic protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000425", "name" : "MIP", "description" : "Major intrinsic protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0015267" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ { "name" : "Passive transport by Aquaporins", "databaseName" : "Reactome", "id" : "R-HSA-432047" } ] } }, "locations" : [ { "start" : 20, "end" : 237, "hmmStart" : 4, "hmmEnd" : 227, "hmmLength" : 227, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.8E-42, "score" : 145.0, "envelopeStart" : 17, "envelopeEnd" : 237, "postProcessed" : true, "location-fragments" : [ { "start" : 20, "end" : 237, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-42, "score" : 145.2, "model-ac" : "PF00230" }, { "signature" : { "accession" : "PR00783", "name" : "MINTRINSICP", "description" : "Major intrinsic protein family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000425", "name" : "MIP", "description" : "Major intrinsic protein", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0015267" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ { "name" : "Passive transport by Aquaporins", "databaseName" : "Reactome", "id" : "R-HSA-432047" } ] } }, "locations" : [ { "start" : 25, "end" : 44, "pvalue" : 2.05E-5, "score" : 31.55, "motifNumber" : 1, "location-fragments" : [ { "start" : 25, "end" : 44, "dc-status" : "CONTINUOUS" } ] }, { "start" : 220, "end" : 240, "pvalue" : 1.57E-10, "score" : 40.85, "motifNumber" : 6, "location-fragments" : [ { "start" : 220, "end" : 240, "dc-status" : "CONTINUOUS" } ] }, { "start" : 183, "end" : 205, "pvalue" : 1.17E-6, "score" : 33.11, "motifNumber" : 5, "location-fragments" : [ { "start" : 183, "end" : 205, "dc-status" : "CONTINUOUS" } ] }, { "start" : 151, "end" : 169, "pvalue" : 6.66E-4, "score" : 26.71, "motifNumber" : 4, "location-fragments" : [ { "start" : 151, "end" : 169, "dc-status" : "CONTINUOUS" } ] }, { "start" : 99, "end" : 118, "pvalue" : 4.93E-5, "score" : 28.46, "motifNumber" : 3, "location-fragments" : [ { "start" : 99, "end" : 118, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-22, "graphscan" : "I.iiII", "model-ac" : "PR00783" } ], "xref" : [ { "name" : "XP_018910506.1 PREDICTED: aquaporin AQPAe.a-like [Bemisia tabaci]", "id" : "XP_018910506.1" } ] },{ "sequence" : "MTEALSSSSAGERRLKELEALFLGGPIQGRGQCFSIETLLDILLVLYDECTNSSLRREKTVSEFIEFVKPVATCVKNLRLSRDDFEMVKVIGRGAFGEVFVVRMKGSEKVFAMKILNKWEMLRRAEIACFQEERDVLVYGDRRWITNLHYAFQDEANLYLVMDYYCGGDLLTLLSKFEDRLPEDMARFYIAEMVLAISSVHDLRYVHRDIKPDNVLLDANGHIRLADFGSCLKLSEDGTVQSNVAVGTPDYISPEILRAMEDGQGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKNCFDFPSDLPVEVTNDAKDLMKRLICSAEYRLGQNGVEDFKNHAWFLGIDWSSLRDSTAPYLPEVSSPTDTSNFDVDDMDIRTSDSVPPTASNPAFTGLHLPFVGFTFTQGSRVGDLGCITFSDSNIRMSAGGKRMRLHEDQLDCKAEPLNNARKISPTSESTGTNLRKLQDEINTLTKRNCELESELQDLEGHERVRELEKLMRLLKQEKEEVNKEKVEVEEKLKLQEKELKDAVSQKKIAMAEYSEVSDKLSDLRQQKQKLSRIVRDKEEELEQAMQKIDSLRQDMRRGEKLRRELEARIDEAMQEATKERKLRERSEEYCNQLKAEWKQLKERRDTGSGDGSSAISQHNIQEINRLKTELETLEVEYSDNLSQQQARHREEINNLREQLLEAEARKEVLEKEVAAAKEKLDTARLESITENEEALATLARRHDSEKMRLLEENKRLALDVDTLNAGRLQETEMGNKKESIAQWEAQISEIIQWVNDEKDARGYLQALATKMTEELEYLKHTAVSTNTVDKSWRNRRSQKLEKMELLNLQSSLQSEIQAKQTIGDELSRTRAELIAAQKELREFHQRFDNLVVDVKRKEIQLKELQARLDSGEGFLERPGSQMSYLDHFLKESSVTRQLRDSITSEEGNLDDNQTLSVASSKTNLSDMNMEQSSLKLQPRVLSSNMMIAKSHQFLIRTFSAPTKCNHCTSLMIGLTRQGVVCEVCGFACHTTCCDKVPIACPVPPDQTKRPLGIDPTRGIGTAYEGYVKVPRAGGVKKGWVRQFVVVCDFKLFLYDISADRNALPSVQVSQVLDMRDEHFSVSSVRESDVIHAMKKDIPCIFRITTSLLEPSELQNHTLMLADTESEKSKWVVALSELHRILKRNNLPNTTVFKAKQVMDSTLRAVMSGAIVDPDRLVIGTEDGLFCLDLDHSEMARVGEGKKVFEMEYIEKEQLLLVLSGKQRHVRLIPVRALDGDEVEWIKVTESKGCITFAVGQLSRNVHCLCVAIKRQNTSQIIIYEITRTRQRHKRMREVMIPTQVQTVQVLSEARLCVGYQSGFSIYNISGDHLAMPLIGTDNPVASFLSYSNSEALKCIELPRGEFLLVFQTLGIYVDSQGRKSRDKEIMYPAYPIAVSYSDGYLLVFSEIHVDVFNVETGDWVQTLNTKRALPLDTHGSLAICLVNDLTHLIYLHNLHQRELLNLTTFDASGREIPRTRRRFSLREGNRASRAPDRRSKMISAPSNFNHISHMGPGDGIQVQRLLDLPTTIETADNAPSPYPKVLHAPPVPLKMSHPPPRHPPPRIPMHPPHNGSSIRRAPAPPRPTPDSVSLYHDFKDQNTSPRHSIASNNSSNPSTPPSPGRDSSCDS", "md5" : "6fc25b89166f83612a3ab765e29d2637", "matches" : [ { "signature" : { "accession" : "SM00285", "name" : "PBD_5", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000095", "name" : "CRIB_dom", "description" : "CRIB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1537, "end" : 1574, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 4.6E-7, "score" : 39.5, "location-fragments" : [ { "start" : 1537, "end" : 1574, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-7, "score" : 39.5, "model-ac" : "SM00285" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 473, "end" : 493, "location-fragments" : [ { "start" : 473, "end" : 493, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF00130", "name" : "C1_1", "description" : "Phorbol esters/diacylglycerol binding domain (C1 domain)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 990, "end" : 1040, "hmmStart" : 1, "hmmEnd" : 51, "hmmLength" : 53, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.0E-11, "score" : 42.6, "envelopeStart" : 990, "envelopeEnd" : 1041, "postProcessed" : true, "location-fragments" : [ { "start" : 990, "end" : 1040, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-11, "score" : 43.8, "model-ac" : "PF00130" }, { "signature" : { "accession" : "SM00109", "name" : "c1_12", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 990, "end" : 1039, "hmmStart" : 1, "hmmEnd" : 61, "hmmLength" : 61, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-12, "score" : 57.7, "location-fragments" : [ { "start" : 990, "end" : 1039, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-12, "score" : 57.7, "model-ac" : "SM00109" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1566, "end" : 1666, "location-fragments" : [ { "start" : 1566, "end" : 1666, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd05597", "name" : "STKc_DMPK_like", "description" : "STKc_DMPK_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 83, "end" : 415, "sites" : [ { "description" : "ATP binding site", "numLocations" : 20, "siteLocations" : [ { "start" : 164, "end" : 164, "residue" : "Y" }, { "start" : 92, "end" : 92, "residue" : "G" }, { "start" : 114, "end" : 114, "residue" : "K" }, { "start" : 163, "end" : 163, "residue" : "D" }, { "start" : 227, "end" : 227, "residue" : "D" }, { "start" : 112, "end" : 112, "residue" : "A" }, { "start" : 165, "end" : 165, "residue" : "Y" }, { "start" : 169, "end" : 169, "residue" : "D" }, { "start" : 91, "end" : 91, "residue" : "I" }, { "start" : 95, "end" : 95, "residue" : "A" }, { "start" : 216, "end" : 216, "residue" : "L" }, { "start" : 209, "end" : 209, "residue" : "D" }, { "start" : 214, "end" : 214, "residue" : "N" }, { "start" : 146, "end" : 146, "residue" : "T" }, { "start" : 211, "end" : 211, "residue" : "K" }, { "start" : 94, "end" : 94, "residue" : "G" }, { "start" : 213, "end" : 213, "residue" : "D" }, { "start" : 93, "end" : 93, "residue" : "R" }, { "start" : 99, "end" : 99, "residue" : "V" }, { "start" : 226, "end" : 226, "residue" : "A" } ] }, { "description" : "polypeptide substrate binding site", "numLocations" : 16, "siteLocations" : [ { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 169, "end" : 169, "residue" : "D" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 95, "end" : 95, "residue" : "A" }, { "start" : 249, "end" : 249, "residue" : "P" }, { "start" : 291, "end" : 291, "residue" : "Y" }, { "start" : 282, "end" : 282, "residue" : "E" }, { "start" : 245, "end" : 245, "residue" : "A" }, { "start" : 288, "end" : 288, "residue" : "T" }, { "start" : 230, "end" : 230, "residue" : "S" }, { "start" : 209, "end" : 209, "residue" : "D" }, { "start" : 250, "end" : 250, "residue" : "D" }, { "start" : 171, "end" : 171, "residue" : "L" }, { "start" : 211, "end" : 211, "residue" : "K" }, { "start" : 213, "end" : 213, "residue" : "D" }, { "start" : 248, "end" : 248, "residue" : "T" } ] }, { "description" : "activation loop (A-loop)", "numLocations" : 23, "siteLocations" : [ { "start" : 234, "end" : 234, "residue" : "L" }, { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 227, "end" : 227, "residue" : "D" }, { "start" : 228, "end" : 228, "residue" : "F" }, { "start" : 236, "end" : 236, "residue" : "E" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 239, "end" : 239, "residue" : "T" }, { "start" : 249, "end" : 249, "residue" : "P" }, { "start" : 242, "end" : 242, "residue" : "S" }, { "start" : 229, "end" : 229, "residue" : "G" }, { "start" : 240, "end" : 240, "residue" : "V" }, { "start" : 245, "end" : 245, "residue" : "A" }, { "start" : 235, "end" : 235, "residue" : "S" }, { "start" : 230, "end" : 230, "residue" : "S" }, { "start" : 232, "end" : 232, "residue" : "L" }, { "start" : 244, "end" : 244, "residue" : "V" }, { "start" : 241, "end" : 241, "residue" : "Q" }, { "start" : 243, "end" : 243, "residue" : "N" }, { "start" : 250, "end" : 250, "residue" : "D" }, { "start" : 231, "end" : 231, "residue" : "C" }, { "start" : 226, "end" : 226, "residue" : "A" }, { "start" : 233, "end" : 233, "residue" : "K" }, { "start" : 248, "end" : 248, "residue" : "T" } ] }, { "description" : "active site", "numLocations" : 31, "siteLocations" : [ { "start" : 92, "end" : 92, "residue" : "G" }, { "start" : 114, "end" : 114, "residue" : "K" }, { "start" : 246, "end" : 246, "residue" : "V" }, { "start" : 163, "end" : 163, "residue" : "D" }, { "start" : 227, "end" : 227, "residue" : "D" }, { "start" : 162, "end" : 162, "residue" : "M" }, { "start" : 165, "end" : 165, "residue" : "Y" }, { "start" : 95, "end" : 95, "residue" : "A" }, { "start" : 249, "end" : 249, "residue" : "P" }, { "start" : 291, "end" : 291, "residue" : "Y" }, { "start" : 245, "end" : 245, "residue" : "A" }, { "start" : 209, "end" : 209, "residue" : "D" }, { "start" : 250, "end" : 250, "residue" : "D" }, { "start" : 214, "end" : 214, "residue" : "N" }, { "start" : 146, "end" : 146, "residue" : "T" }, { "start" : 211, "end" : 211, "residue" : "K" }, { "start" : 94, "end" : 94, "residue" : "G" }, { "start" : 99, "end" : 99, "residue" : "V" }, { "start" : 226, "end" : 226, "residue" : "A" }, { "start" : 112, "end" : 112, "residue" : "A" }, { "start" : 169, "end" : 169, "residue" : "D" }, { "start" : 247, "end" : 247, "residue" : "G" }, { "start" : 91, "end" : 91, "residue" : "I" }, { "start" : 282, "end" : 282, "residue" : "E" }, { "start" : 288, "end" : 288, "residue" : "T" }, { "start" : 230, "end" : 230, "residue" : "S" }, { "start" : 216, "end" : 216, "residue" : "L" }, { "start" : 171, "end" : 171, "residue" : "L" }, { "start" : 213, "end" : 213, "residue" : "D" }, { "start" : 93, "end" : 93, "residue" : "R" }, { "start" : 248, "end" : 248, "residue" : "T" } ] }, { "description" : "hydrophobic motif (HM)", "numLocations" : 6, "siteLocations" : [ { "start" : 409, "end" : 409, "residue" : "F" }, { "start" : 414, "end" : 414, "residue" : "F" }, { "start" : 412, "end" : 412, "residue" : "F" }, { "start" : 410, "end" : 410, "residue" : "V" }, { "start" : 413, "end" : 413, "residue" : "T" }, { "start" : 411, "end" : 411, "residue" : "G" } ] } ], "evalue" : 0.0, "score" : 734.153, "location-fragments" : [ { "start" : 83, "end" : 415, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd05597" }, { "signature" : { "accession" : "cd01243", "name" : "PH_MRCK", "description" : "PH_MRCK", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1049, "end" : 1183, "sites" : [ ], "evalue" : 3.67471E-83, "score" : 266.47, "location-fragments" : [ { "start" : 1049, "end" : 1183, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01243" }, { "signature" : { "accession" : "PTHR22988:SF66", "name" : "SERINE/THREONINE-PROTEIN KINASE GENGHIS KHAN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 1577, "hmmStart" : 5, "hmmEnd" : 1527, "hmmLength" : 1548, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 1654, "location-fragments" : [ { "start" : 12, "end" : 1577, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "SERINE/THREONINE-PROTEIN KINASE GENGHIS KHAN", "score" : 2155.4, "model-ac" : "PTHR22988:SF66" }, { "signature" : { "accession" : "PS50108", "name" : "CRIB", "description" : "CRIB domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000095", "name" : "CRIB_dom", "description" : "CRIB domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1537, "end" : 1550, "score" : 8.837, "alignment" : "ISAPSNFNHISHMG", "location-fragments" : [ { "start" : 1537, "end" : 1550, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50108" }, { "signature" : { "accession" : "SM00036", "name" : "nik_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001180", "name" : "CNH_dom", "description" : "Citron homology (CNH) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1201, "end" : 1492, "hmmStart" : 1, "hmmEnd" : 375, "hmmLength" : 375, "hmmBounds" : "COMPLETE", "evalue" : 6.7E-21, "score" : 85.4, "location-fragments" : [ { "start" : 1201, "end" : 1492, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-21, "score" : 85.4, "model-ac" : "SM00036" }, { "signature" : { "accession" : "PS51285", "name" : "AGC_KINASE_CTER", "description" : "AGC-kinase C-terminal domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000961", "name" : "AGC-kinase_C", "description" : "AGC-kinase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein serine/threonine kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004674" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 353, "end" : 424, "score" : 12.7, "alignment" : "LGIDWSSL--RDSTAPYLPEVSSPTDTSNFdvDDMDIRTSDSVPPTASNPAFTGLHLPFVGFTFTQGSRVGDLG", "location-fragments" : [ { "start" : 353, "end" : 424, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51285" }, { "signature" : { "accession" : "SM00133", "name" : "pkinase_C_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000961", "name" : "AGC-kinase_C", "description" : "AGC-kinase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein serine/threonine kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004674" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 353, "end" : 416, "hmmStart" : 1, "hmmEnd" : 79, "hmmLength" : 79, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-7, "score" : 40.6, "location-fragments" : [ { "start" : 353, "end" : 416, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-7, "score" : 40.6, "model-ac" : "SM00133" }, { "signature" : { "accession" : "PS50081", "name" : "ZF_DAG_PE_2", "description" : "Zinc finger phorbol-ester/DAG-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 989, "end" : 1039, "score" : 14.189, "alignment" : "SHQFLIRTFSAPTKCNHCTSLMIGLTRQGVVCEVCGFACHTTCCDKVPIAC", "location-fragments" : [ { "start" : 989, "end" : 1039, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50081" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1630, "end" : 1666, "location-fragments" : [ { "start" : 1630, "end" : 1666, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1578, "end" : 1606, "location-fragments" : [ { "start" : 1578, "end" : 1606, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00029", "name" : "C1", "description" : "C1", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 990, "end" : 1039, "sites" : [ { "description" : "putative DAG/PE binding site", "numLocations" : 10, "siteLocations" : [ { "start" : 1010, "end" : 1010, "residue" : "M" }, { "start" : 1016, "end" : 1016, "residue" : "Q" }, { "start" : 1012, "end" : 1012, "residue" : "G" }, { "start" : 1014, "end" : 1014, "residue" : "T" }, { "start" : 1000, "end" : 1000, "residue" : "P" }, { "start" : 1001, "end" : 1001, "residue" : "T" }, { "start" : 1013, "end" : 1013, "residue" : "L" }, { "start" : 1011, "end" : 1011, "residue" : "I" }, { "start" : 997, "end" : 997, "residue" : "F" }, { "start" : 1015, "end" : 1015, "residue" : "R" } ] }, { "description" : "putative RAS interaction site", "numLocations" : 2, "siteLocations" : [ { "start" : 1002, "end" : 1002, "residue" : "K" }, { "start" : 1000, "end" : 1000, "residue" : "P" } ] }, { "description" : "zinc binding sites", "numLocations" : 8, "siteLocations" : [ { "start" : 1003, "end" : 1003, "residue" : "C" }, { "start" : 1006, "end" : 1006, "residue" : "C" }, { "start" : 1028, "end" : 1028, "residue" : "H" }, { "start" : 1020, "end" : 1020, "residue" : "C" }, { "start" : 1023, "end" : 1023, "residue" : "C" }, { "start" : 1031, "end" : 1031, "residue" : "C" }, { "start" : 1039, "end" : 1039, "residue" : "C" }, { "start" : 990, "end" : 990, "residue" : "H" } ] } ], "evalue" : 2.45781E-16, "score" : 72.5247, "location-fragments" : [ { "start" : 990, "end" : 1039, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00029" }, { "signature" : { "accession" : "PS50003", "name" : "PH_DOMAIN", "description" : "PH domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001849", "name" : "PH_domain", "description" : "Pleckstrin homology domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1059, "end" : 1178, "score" : 9.125, "alignment" : "GTAYEGYVKVPRAGgVKKGWVRQFVVVCDFKLFLYDISadrNALPSVQVSQVLDMRDEHFSVSSVRESDVihamkkdIPCIFRITTSLLEpselqNHTLMLADTESEKSKWVVALSELHR", "location-fragments" : [ { "start" : 1059, "end" : 1178, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50003" }, { "signature" : { "accession" : "PF00433", "name" : "Pkinase_C", "description" : "Protein kinase C terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR017892", "name" : "Pkinase_C", "description" : "Protein kinase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein serine/threonine kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004674" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 371, "end" : 414, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 7.1E-5, "score" : 23.4, "envelopeStart" : 371, "envelopeEnd" : 414, "postProcessed" : true, "location-fragments" : [ { "start" : 371, "end" : 414, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-5, "score" : 24.7, "model-ac" : "PF00433" }, { "signature" : { "accession" : "G3DSA:2.30.29.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011993", "name" : "PH-like_dom_sf", "description" : "PH-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1061, "end" : 1178, "hmmStart" : 3, "hmmEnd" : 111, "hmmLength" : 117, "hmmBounds" : "COMPLETE", "evalue" : 5.0E-42, "score" : 144.9, "envelopeStart" : 1061, "envelopeEnd" : 1178, "postProcessed" : true, "location-fragments" : [ { "start" : 1061, "end" : 1178, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-42, "score" : 146.7, "model-ac" : "2rovA00" }, { "signature" : { "accession" : "cd00132", "name" : "CRIB", "description" : "CRIB", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1535, "end" : 1571, "sites" : [ { "description" : "GTPase interaction site", "numLocations" : 7, "siteLocations" : [ { "start" : 1545, "end" : 1545, "residue" : "H" }, { "start" : 1567, "end" : 1567, "residue" : "I" }, { "start" : 1548, "end" : 1548, "residue" : "H" }, { "start" : 1543, "end" : 1543, "residue" : "F" }, { "start" : 1563, "end" : 1563, "residue" : "L" }, { "start" : 1540, "end" : 1540, "residue" : "P" }, { "start" : 1537, "end" : 1537, "residue" : "I" } ] } ], "evalue" : 1.68702E-8, "score" : 49.7445, "location-fragments" : [ { "start" : 1535, "end" : 1571, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00132" }, { "signature" : { "accession" : "SSF50729", "name" : "PH domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 1058, "end" : 1179, "hmmLength" : 123, "location-fragments" : [ { "start" : 1058, "end" : 1179, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.92E-9, "model-ac" : "0050619" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 61, "end" : 403, "hmmLength" : 353, "location-fragments" : [ { "start" : 61, "end" : 403, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.88E-80, "model-ac" : "0040180" }, { "signature" : { "accession" : "SM00220", "name" : "serkin_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 85, "end" : 352, "hmmStart" : 1, "hmmEnd" : 231, "hmmLength" : 231, "hmmBounds" : "COMPLETE", "evalue" : 3.2E-81, "score" : 285.8, "location-fragments" : [ { "start" : 85, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-81, "score" : 285.8, "model-ac" : "SM00220" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 865, "end" : 906, "location-fragments" : [ { "start" : 865, "end" : 906, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PS00107", "name" : "PROTEIN_KINASE_ATP", "description" : "Protein kinases ATP-binding region signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017441", "name" : "Protein_kinase_ATP_BS", "description" : "Protein kinase, ATP binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 91, "end" : 114, "level" : "STRONG", "cigarAlignment" : "10M1I1M8I4M", "alignment" : "IGRGAFGEVFvVrmkgsekvFAMK", "location-fragments" : [ { "start" : 91, "end" : 114, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00107" }, { "signature" : { "accession" : "PR00008", "name" : "DAGPEDOMAIN", "description" : "Diacylglycerol/phorbol-ester binding signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR020454", "name" : "DAG/PE-bd", "description" : "Diacylglycerol/phorbol-ester binding", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 987, "end" : 1001, "pvalue" : 1.03E-4, "score" : 35.31, "motifNumber" : 1, "location-fragments" : [ { "start" : 987, "end" : 1001, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1003, "end" : 1012, "pvalue" : 0.00731, "score" : 40.99, "motifNumber" : 2, "location-fragments" : [ { "start" : 1003, "end" : 1012, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1028, "end" : 1040, "pvalue" : 0.0136, "score" : 36.1, "motifNumber" : 4, "location-fragments" : [ { "start" : 1028, "end" : 1040, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1016, "end" : 1027, "pvalue" : 0.00188, "score" : 43.23, "motifNumber" : 3, "location-fragments" : [ { "start" : 1016, "end" : 1027, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-5, "graphscan" : "IIII", "model-ac" : "PR00008" }, { "signature" : { "accession" : "PS50219", "name" : "CNH", "description" : "Citron homology (CNH) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001180", "name" : "CNH_dom", "description" : "Citron homology (CNH) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1201, "end" : 1477, "score" : 23.8, "alignment" : "LRAVMSGAIVDPDRLVIGTEDGLFCL----DLD---HSEMARVGEGKKVFEMEYIEKEQLLLVLSgkQRHVRLIPVRALDG-DEVEWIKVTESKGCITFAVGQLSRNVhCLCVAIKRQNTSQIIIYEItRTRQRHKRMREVMIPTQVQTVQVLSEARLCVGYQSGFSIYNISgDHLAMPLIGTDNPVASflSYSNSEALKCIELPRGEFLLVFQTLGIYVDSQGRKSRDK-EIMYPAYPIAVSYSDGYLLVFSEIHVDVFNVETGDWVQTLNTKRALPLDTHGSLA", "location-fragments" : [ { "start" : 1201, "end" : 1477, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50219" }, { "signature" : { "accession" : "SM00233", "name" : "PH_update", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001849", "name" : "PH_domain", "description" : "Pleckstrin homology domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1060, "end" : 1180, "hmmStart" : 1, "hmmEnd" : 82, "hmmLength" : 82, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-6, "score" : 37.1, "location-fragments" : [ { "start" : 1060, "end" : 1180, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-6, "score" : 37.1, "model-ac" : "SM00233" }, { "signature" : { "accession" : "PF15796", "name" : "KELK", "description" : "KELK-motif containing domain of MRCK Ser/Thr protein kinase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR031597", "name" : "KELK", "description" : "KELK-motif containing domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Thermogenesis", "databaseName" : "KEGG", "id" : "04714+2.7.11.1" }, { "name" : "Human papillomavirus infection", "databaseName" : "KEGG", "id" : "05165+2.7.11.1" }, { "name" : "Human cytomegalovirus infection", "databaseName" : "KEGG", "id" : "05163+2.7.11.1" }, { "name" : "mTOR signaling pathway", "databaseName" : "KEGG", "id" : "04150+2.7.11.1" }, { "name" : "Relaxin signaling pathway", "databaseName" : "KEGG", "id" : "04926+2.7.11.1" }, { "name" : "Human immunodeficiency virus 1 infection", "databaseName" : "KEGG", "id" : "05170+2.7.11.1" }, { "name" : "PI3K-Akt signaling pathway", "databaseName" : "KEGG", "id" : "04151+2.7.11.1" } ] } }, "locations" : [ { "start" : 502, "end" : 581, "hmmStart" : 1, "hmmEnd" : 80, "hmmLength" : 80, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-28, "score" : 98.3, "envelopeStart" : 502, "envelopeEnd" : 581, "postProcessed" : true, "location-fragments" : [ { "start" : 502, "end" : 581, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-28, "score" : 98.3, "model-ac" : "PF15796" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 503, "end" : 642, "location-fragments" : [ { "start" : 503, "end" : 642, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR22988", "name" : "MYOTONIC DYSTROPHY S/T KINASE-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 1577, "hmmStart" : 5, "hmmEnd" : 1527, "hmmLength" : 1548, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 8, "envelopeEnd" : 1654, "location-fragments" : [ { "start" : 12, "end" : 1577, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "SERINE/THREONINE-PROTEIN KINASE GENGHIS KHAN", "score" : 2155.4, "model-ac" : "PTHR22988" }, { "signature" : { "accession" : "PS00108", "name" : "PROTEIN_KINASE_ST", "description" : "Serine/Threonine protein kinases active-site signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR008271", "name" : "Ser/Thr_kinase_AS", "description" : "Serine/threonine-protein kinase, active site", "type" : "ACTIVE_SITE", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 205, "end" : 217, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I3M2I4M", "alignment" : "YvHrDIKpdNVLL", "location-fragments" : [ { "start" : 205, "end" : 217, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00108" }, { "signature" : { "accession" : "PF00069", "name" : "Pkinase", "description" : "Protein kinase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 86, "end" : 352, "hmmStart" : 2, "hmmEnd" : 264, "hmmLength" : 264, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.1E-52, "score" : 177.5, "envelopeStart" : 85, "envelopeEnd" : 352, "postProcessed" : true, "location-fragments" : [ { "start" : 86, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.6E-53, "score" : 179.2, "model-ac" : "PF00069" }, { "signature" : { "accession" : "G3DSA:1.10.510.10", "name" : "Transferase(Phosphotransferase) domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 171, "end" : 374, "hmmStart" : 3, "hmmEnd" : 363, "hmmLength" : 363, "hmmBounds" : "INCOMPLETE", "evalue" : 9.0E-187, "score" : 622.2, "envelopeStart" : 16, "envelopeEnd" : 382, "postProcessed" : true, "location-fragments" : [ { "start" : 171, "end" : 374, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-187, "score" : 623.4, "model-ac" : "3tkuA02" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 655, "end" : 725, "location-fragments" : [ { "start" : 655, "end" : 725, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PS00479", "name" : "ZF_DAG_PE_1", "description" : "Zinc finger phorbol-ester/DAG-type signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR002219", "name" : "PE/DAG-bd", "description" : "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 990, "end" : 1039, "level" : "STRONG", "cigarAlignment" : "1M1I1M10I1M2I1M3I1M9I1M2I1M4I1M2I1M7I1M", "alignment" : "HqFlirtfsaptkCnhCtslMigltrqgvvCevCgfacHttCcdkvpiaC", "location-fragments" : [ { "start" : 990, "end" : 1039, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00479" }, { "signature" : { "accession" : "G3DSA:3.30.200.20", "name" : "Phosphorylase Kinase; domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 382, "hmmStart" : 3, "hmmEnd" : 363, "hmmLength" : 213, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 9.0E-187, "score" : 622.2, "envelopeStart" : 16, "envelopeEnd" : 382, "postProcessed" : true, "location-fragments" : [ { "start" : 375, "end" : 382, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 18, "end" : 170, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 3.8E-187, "score" : 623.4, "model-ac" : "3tkuA01" }, { "signature" : { "accession" : "SSF57889", "name" : "Cysteine-rich domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 979, "end" : 1043, "hmmLength" : 84, "location-fragments" : [ { "start" : 979, "end" : 1043, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.99E-17, "model-ac" : "0043160" }, { "signature" : { "accession" : "G3DSA:3.30.60.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 984, "end" : 1053, "hmmStart" : 7, "hmmEnd" : 67, "hmmLength" : 73, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-17, "score" : 64.5, "envelopeStart" : 984, "envelopeEnd" : 1053, "postProcessed" : true, "location-fragments" : [ { "start" : 984, "end" : 1053, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-17, "score" : 65.4, "model-ac" : "3cxlA02" }, { "signature" : { "accession" : "PF00780", "name" : "CNH", "description" : "CNH domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001180", "name" : "CNH_dom", "description" : "Citron homology (CNH) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1210, "end" : 1472, "hmmStart" : 5, "hmmEnd" : 277, "hmmLength" : 279, "hmmBounds" : "INCOMPLETE", "evalue" : 7.9E-62, "score" : 209.3, "envelopeStart" : 1207, "envelopeEnd" : 1474, "postProcessed" : true, "location-fragments" : [ { "start" : 1210, "end" : 1472, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-62, "score" : 210.3, "model-ac" : "PF00780" }, { "signature" : { "accession" : "PS50011", "name" : "PROTEIN_KINASE_DOM", "description" : "Protein kinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 85, "end" : 352, "score" : 44.202, "alignment" : "FEMVKVIGRGAFGEVFVVRMKGSEKVFAMKILNKWEMLRRaEIACFQEERDVLVYGDRRWITNLHYAFQDEANLYLVMDYYCGGDLLTLLSKFEDRLPEDMARFYIAEMVLAISSVHDLRYVHRDIKPDNVLLDANGHIRLADFGSCLKLSEDGTvQSNVAVGTPDYISPEILRamedGQGRYGPECDWWSLGVCMYEMLYGETPF--YaESLVETYGKIMNH----------KncfdfpsdlpveVTNDAKDLMKRLIC-SAEYRLGQNGVEDfknHAWF", "location-fragments" : [ { "start" : 85, "end" : 352, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50011" } ], "xref" : [ { "name" : "XP_018910546.1 PREDICTED: serine/threonine-protein kinase Genghis Khan isoform X2 [Bemisia tabaci]", "id" : "XP_018910546.1" } ] },{ "sequence" : "MKIRKKVREFRVIGRKMPKNLKEQTPLYRMRIFAPNRIIAKSRFWYFLRQLRKFKKSTGEIVQVKEIFEKDPTTVKNIGIWLRYDHRNGTSNMYREYRALSTCSAVGKMYREMASKHKARVHSIQIIRIATIKEDDVRRPYIKQWLQPNIKFPLVHRIVQKRKLGLFTLRKNINTVYR", "md5" : "872110b697a79eaa8b731b0f4ae7d443", "matches" : [ { "signature" : { "accession" : "PTHR10052", "name" : "60S RIBOSOMAL PROTEIN L18A", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR028877", "name" : "50S_L18Ae/Ribosomal_L18a/L20", "description" : "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "L13a-mediated translational silencing of Ceruloplasmin expression", "databaseName" : "Reactome", "id" : "R-HSA-156827" }, { "name" : "Formation of a pool of free 40S subunits", "databaseName" : "Reactome", "id" : "R-HSA-72689" }, { "name" : "GTP hydrolysis and joining of the 60S ribosomal subunit", "databaseName" : "Reactome", "id" : "R-HSA-72706" }, { "name" : "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975957" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "Response of EIF2AK4 (GCN2) to amino acid deficiency", "databaseName" : "Reactome", "id" : "R-HSA-9633012" }, { "name" : "Eukaryotic Translation Termination", "databaseName" : "Reactome", "id" : "R-HSA-72764" }, { "name" : "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975956" }, { "name" : "Viral mRNA Translation", "databaseName" : "Reactome", "id" : "R-HSA-192823" }, { "name" : "Selenocysteine synthesis", "databaseName" : "Reactome", "id" : "R-HSA-2408557" }, { "name" : "Regulation of expression of SLITs and ROBOs", "databaseName" : "Reactome", "id" : "R-HSA-9010553" }, { "name" : "Peptide chain elongation", "databaseName" : "Reactome", "id" : "R-HSA-156902" }, { "name" : "Major pathway of rRNA processing in the nucleolus and cytosol", "databaseName" : "Reactome", "id" : "R-HSA-6791226" } ] } }, "locations" : [ { "start" : 2, "end" : 163, "hmmStart" : 298, "hmmEnd" : 459, "hmmLength" : 473, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 176, "location-fragments" : [ { "start" : 2, "end" : 163, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.1E-79, "familyName" : "60S RIBOSOMAL PROTEIN L18A", "score" : 268.5, "model-ac" : "PTHR10052" }, { "signature" : { "accession" : "PF01775", "name" : "Ribosomal_L18A", "description" : "Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR023573", "name" : "Ribosomal_L18a//L18Ae/LX", "description" : "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A", "type" : "DOMAIN", "goXRefs" : [ { "name" : "translation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006412" }, { "name" : "structural constituent of ribosome", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003735" }, { "name" : "ribosome", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005840" } ], "pathwayXRefs" : [ { "name" : "Peptide chain elongation", "databaseName" : "Reactome", "id" : "R-HSA-156902" }, { "name" : "Major pathway of rRNA processing in the nucleolus and cytosol", "databaseName" : "Reactome", "id" : "R-HSA-6791226" }, { "name" : "Regulation of expression of SLITs and ROBOs", "databaseName" : "Reactome", "id" : "R-HSA-9010553" }, { "name" : "Response of EIF2AK4 (GCN2) to amino acid deficiency", "databaseName" : "Reactome", "id" : "R-HSA-9633012" }, { "name" : "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975957" }, { "name" : "Selenocysteine synthesis", "databaseName" : "Reactome", "id" : "R-HSA-2408557" }, { "name" : "Viral mRNA Translation", "databaseName" : "Reactome", "id" : "R-HSA-192823" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "GTP hydrolysis and joining of the 60S ribosomal subunit", "databaseName" : "Reactome", "id" : "R-HSA-72706" }, { "name" : "Eukaryotic Translation Termination", "databaseName" : "Reactome", "id" : "R-HSA-72764" }, { "name" : "L13a-mediated translational silencing of Ceruloplasmin expression", "databaseName" : "Reactome", "id" : "R-HSA-156827" }, { "name" : "Formation of a pool of free 40S subunits", "databaseName" : "Reactome", "id" : "R-HSA-72689" }, { "name" : "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975956" } ] } }, "locations" : [ { "start" : 8, "end" : 129, "hmmStart" : 2, "hmmEnd" : 120, "hmmLength" : 121, "hmmBounds" : "INCOMPLETE", "evalue" : 3.3E-49, "score" : 166.0, "envelopeStart" : 7, "envelopeEnd" : 130, "postProcessed" : true, "location-fragments" : [ { "start" : 8, "end" : 129, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.7E-49, "score" : 166.3, "model-ac" : "PF01775" }, { "signature" : { "accession" : "G3DSA:3.10.20.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 72, "hmmStart" : 3, "hmmEnd" : 71, "hmmLength" : 71, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-31, "score" : 110.1, "envelopeStart" : 2, "envelopeEnd" : 72, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 72, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-32, "score" : 111.3, "model-ac" : "1vwxS01" }, { "signature" : { "accession" : "SSF160374", "name" : "RplX-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 72, "end" : 146, "hmmLength" : 78, "location-fragments" : [ { "start" : 72, "end" : 146, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.62E-24, "model-ac" : "0054246" }, { "signature" : { "accession" : "PTHR10052:SF1", "name" : "60S RIBOSOMAL PROTEIN L18A", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 163, "hmmStart" : 298, "hmmEnd" : 459, "hmmLength" : 473, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 176, "location-fragments" : [ { "start" : 2, "end" : 163, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.1E-79, "familyName" : "60S RIBOSOMAL PROTEIN L18A", "score" : 268.5, "model-ac" : "PTHR10052:SF1" }, { "signature" : { "accession" : "MF_00273", "name" : "Ribosomal_L18Ae", "description" : "50S ribosomal protein L18Ae [rpl18a].", "signatureLibraryRelease" : { "library" : "HAMAP", "version" : "2020_01" }, "entry" : { "accession" : "IPR028877", "name" : "50S_L18Ae/Ribosomal_L18a/L20", "description" : "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "L13a-mediated translational silencing of Ceruloplasmin expression", "databaseName" : "Reactome", "id" : "R-HSA-156827" }, { "name" : "Formation of a pool of free 40S subunits", "databaseName" : "Reactome", "id" : "R-HSA-72689" }, { "name" : "GTP hydrolysis and joining of the 60S ribosomal subunit", "databaseName" : "Reactome", "id" : "R-HSA-72706" }, { "name" : "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975957" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "Response of EIF2AK4 (GCN2) to amino acid deficiency", "databaseName" : "Reactome", "id" : "R-HSA-9633012" }, { "name" : "Eukaryotic Translation Termination", "databaseName" : "Reactome", "id" : "R-HSA-72764" }, { "name" : "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975956" }, { "name" : "Viral mRNA Translation", "databaseName" : "Reactome", "id" : "R-HSA-192823" }, { "name" : "Selenocysteine synthesis", "databaseName" : "Reactome", "id" : "R-HSA-2408557" }, { "name" : "Regulation of expression of SLITs and ROBOs", "databaseName" : "Reactome", "id" : "R-HSA-9010553" }, { "name" : "Peptide chain elongation", "databaseName" : "Reactome", "id" : "R-HSA-156902" }, { "name" : "Major pathway of rRNA processing in the nucleolus and cytosol", "databaseName" : "Reactome", "id" : "R-HSA-6791226" } ] } }, "locations" : [ { "start" : 7, "end" : 70, "score" : 21.121, "alignment" : "VREFRVIGRKMPKNLKEQT-PLYRMRIFAPNRIIAKSRFWYFLRQLRKFKKSTGEIVQVKEIFEK", "location-fragments" : [ { "start" : 7, "end" : 70, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "MF_00273" }, { "signature" : { "accession" : "G3DSA:3.10.20.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 74, "end" : 147, "hmmStart" : 3, "hmmEnd" : 73, "hmmLength" : 76, "hmmBounds" : "COMPLETE", "evalue" : 3.1E-32, "score" : 112.5, "envelopeStart" : 74, "envelopeEnd" : 147, "postProcessed" : true, "location-fragments" : [ { "start" : 74, "end" : 147, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-32, "score" : 112.5, "model-ac" : "1vx7U02" }, { "signature" : { "accession" : "PIRSF002190", "name" : "Ribosomal_L18a", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR021138", "name" : "Ribosomal_L18a/L20_eukaryotes", "description" : "60S ribosomal protein L18a/ L20, eukaryotes", "type" : "FAMILY", "goXRefs" : [ { "name" : "translation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006412" }, { "name" : "structural constituent of ribosome", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003735" }, { "name" : "ribosome", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005840" } ], "pathwayXRefs" : [ { "name" : "Response of EIF2AK4 (GCN2) to amino acid deficiency", "databaseName" : "Reactome", "id" : "R-HSA-9633012" }, { "name" : "Regulation of expression of SLITs and ROBOs", "databaseName" : "Reactome", "id" : "R-HSA-9010553" }, { "name" : "SRP-dependent cotranslational protein targeting to membrane", "databaseName" : "Reactome", "id" : "R-HSA-1799339" }, { "name" : "Selenocysteine synthesis", "databaseName" : "Reactome", "id" : "R-HSA-2408557" }, { "name" : "Peptide chain elongation", "databaseName" : "Reactome", "id" : "R-HSA-156902" }, { "name" : "Viral mRNA Translation", "databaseName" : "Reactome", "id" : "R-HSA-192823" }, { "name" : "Formation of a pool of free 40S subunits", "databaseName" : "Reactome", "id" : "R-HSA-72689" }, { "name" : "GTP hydrolysis and joining of the 60S ribosomal subunit", "databaseName" : "Reactome", "id" : "R-HSA-72706" }, { "name" : "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975956" }, { "name" : "Eukaryotic Translation Termination", "databaseName" : "Reactome", "id" : "R-HSA-72764" }, { "name" : "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "databaseName" : "Reactome", "id" : "R-HSA-975957" }, { "name" : "L13a-mediated translational silencing of Ceruloplasmin expression", "databaseName" : "Reactome", "id" : "R-HSA-156827" }, { "name" : "Major pathway of rRNA processing in the nucleolus and cytosol", "databaseName" : "Reactome", "id" : "R-HSA-6791226" } ] } }, "locations" : [ { "start" : 1, "end" : 176, "hmmStart" : 6, "hmmEnd" : 164, "hmmLength" : 173, "hmmBounds" : "INCOMPLETE", "evalue" : 2.7E-67, "score" : 221.3, "envelopeStart" : 1, "envelopeEnd" : 176, "postProcessed" : false, "location-fragments" : [ { "start" : 1, "end" : 176, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-67, "score" : 221.5, "model-ac" : "PIRSF002190" } ], "xref" : [ { "name" : "XP_018910361.1 PREDICTED: 60S ribosomal protein L18a [Bemisia tabaci]", "id" : "XP_018910361.1" } ] },{ "sequence" : "MSRYNREVNSLFNASENPAWAEVSRRPIGELGDVPFSYFLGRPVEGLLRRALNRSLEESLDPANDRRRIEKRLQDLRQAVNAALNHTLNDIVNESLDYVFQLDDQDFDYVSGRQWFRIRNLSLENIFDSMLQANGANMTGVETLLRIAWRLFLNQQQESFEKFLSNPGEVVAWIFNTYMNLFGNNRTGIFNREALRGFVQYYTATESYRVTIPLCYAPIPASSLCWNINFMINTNKWTVRKTVNLAAESNLLAADPFVLELFDMDLNLTGFRERRQEGVCANGRISMLDMDGYPFPKFELGCHPVFYHPLQYVDQVLCLLYERTVTSRNSLRNTTLGKVCIDPIQATLMHELTRNFIRMTVRNNNLQPSSNKVCKNMVYQLHTLGAGTPRDELMSRAITEMLSYSITNLLGVRSDRRTILNFVRLARAAPILMDAWGAIAQNSNSTEQFNRNLMECGVLLLQHGEEHRTLALHPTPPPQPPTSPPNRLRDLLRRRISDHRLAPPAPSSNRRIRQVDDLEMSQWDDLSGTREEGQIGDPRDDDIPTIQQIQGQSALKNSLAALFRQLDEMRFRLRDFLDGQRVNFESRLDGLWDRYANTIRAWLESFLARVLGTVTQYAPLITRHPG", "md5" : "f6bbe03a7b3d0c9dff026241fe8abbb9", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 66, "end" : 86, "location-fragments" : [ { "start" : 66, "end" : 86, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 467, "end" : 514, "location-fragments" : [ { "start" : 467, "end" : 514, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909730.1 PREDICTED: uncharacterized protein LOC109038914 isoform X3 [Bemisia tabaci]", "id" : "XP_018909730.1" } ] },{ "sequence" : "MYAMPHTNALQRQLADSIVRMVPLDDIRILLACGAKVNEPVTQGLRPLHYAVWQRYPEAVRLLLIRGGDVNARDESGYSALHLSAEHGYTELVALLLAQGAQVDYREDTDDPFPRTTVCDEPLRLAIRNRHADVARLLLEHGADPNKRYFSGSEINLVSPLDLEFMNLLLTYGADPNTRDRAGLTPLMKAARLPQGMDSVLLLISYGADVNAMTDARHDYRTVLHYAVLSGNNAIVNLLLKQGAKLNFTTDYAKPTPLDLAILKGDISLVKMLLVSGANVNSNSPIIGSPLHVVCADSIENRLEILHMLLVAGADPNLVIDSDEGPPLRPVLSEYMASNEKPCPHVVSLLLRYGAKVVMKTQFRDPHGILNSLQNISNTPVIFELLLDAAESFDVCMIRRSAHLSPEQKERLLKVATAPLSLRHQARLSIRKHMGNKLITRVEALPIPTVLHRYLIYDFY", "md5" : "23a5f4f8f0b2be4004b6ff71a60d9ce2", "matches" : [ { "signature" : { "accession" : "G3DSA:1.25.40.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 159, "end" : 375, "hmmStart" : 31, "hmmEnd" : 211, "hmmLength" : 244, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.9E-40, "score" : 139.0, "envelopeStart" : 158, "envelopeEnd" : 375, "postProcessed" : true, "location-fragments" : [ { "start" : 159, "end" : 375, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-79, "score" : 269.0, "model-ac" : "3d9hA00" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 122, "end" : 150, "score" : 9.538, "alignment" : "----PLRLAIRNRHADVARLLLEHGADPNKRYF", "location-fragments" : [ { "start" : 122, "end" : 150, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "PS50297", "name" : "ANK_REP_REGION", "description" : "Ankyrin repeat region circular profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR020683", "name" : "Ankyrin_rpt-contain_dom", "description" : "Ankyrin repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 27, "end" : 362, "score" : 63.269, "alignment" : "-----------------IRILLACGAKVNEPVTQGLRPLHYAVWQRYPEAVRLLLIRGGDVNARDESGYSALHLSAEHGYTELVALLLAQGAQVDYREDtddpfprttVCDEPLRLAIRNRHADVARLLLEHGADPNKRYFSGSEINLVSPLDLE--FMNLLLTYGADPNTRDRAGLTPLMKAARLPQGMdSVLLLISYGADVNAMTDarhDYRTVLHYAVLSGNNAIVNLLLKQGAKLNFTTDyAKPTPLDLAILKGDISLVKMLLVSGANVNSNSPIIGSPLHVVCADSIENrleILHMLLVAGADPNLVIDsDEGPPLRPVLSEYMASnekpcphVVSLLLRYGAKVVMKTQ", "location-fragments" : [ { "start" : 27, "end" : 362, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50297" }, { "signature" : { "accession" : "PF12796", "name" : "Ank_2", "description" : "Ankyrin repeats (3 copies)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR020683", "name" : "Ankyrin_rpt-contain_dom", "description" : "Ankyrin repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 163, "end" : 249, "hmmStart" : 10, "hmmEnd" : 82, "hmmLength" : 83, "hmmBounds" : "INCOMPLETE", "evalue" : 4.4E-11, "score" : 43.2, "envelopeStart" : 158, "envelopeEnd" : 250, "postProcessed" : true, "location-fragments" : [ { "start" : 163, "end" : 249, "dc-status" : "CONTINUOUS" } ] }, { "start" : 27, "end" : 104, "hmmStart" : 13, "hmmEnd" : 80, "hmmLength" : 83, "hmmBounds" : "INCOMPLETE", "evalue" : 9.1E-11, "score" : 42.2, "envelopeStart" : 21, "envelopeEnd" : 107, "postProcessed" : true, "location-fragments" : [ { "start" : 27, "end" : 104, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-43, "score" : 145.7, "model-ac" : "PF12796" }, { "signature" : { "accession" : "SSF48403", "name" : "Ankyrin repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 251, "end" : 362, "hmmLength" : 221, "location-fragments" : [ { "start" : 251, "end" : 362, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.03E-8, "model-ac" : "0047382" }, { "signature" : { "accession" : "PR01415", "name" : "ANKYRIN", "description" : "Ankyrin repeat signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 134, "end" : 148, "pvalue" : 1.73E-7, "score" : 43.04, "motifNumber" : 2, "location-fragments" : [ { "start" : 134, "end" : 148, "dc-status" : "CONTINUOUS" } ] }, { "start" : 77, "end" : 92, "pvalue" : 1.68E-6, "score" : 33.29, "motifNumber" : 1, "location-fragments" : [ { "start" : 77, "end" : 92, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-7, "graphscan" : "II", "model-ac" : "PR01415" }, { "signature" : { "accession" : "PTHR24189", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 199, "end" : 281, "hmmStart" : 225, "hmmEnd" : 303, "hmmLength" : 378, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 193, "envelopeEnd" : 285, "location-fragments" : [ { "start" : 199, "end" : 281, "dc-status" : "CONTINUOUS" } ] }, { "start" : 67, "end" : 152, "hmmStart" : 233, "hmmEnd" : 309, "hmmLength" : 378, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 66, "envelopeEnd" : 155, "location-fragments" : [ { "start" : 67, "end" : 152, "dc-status" : "CONTINUOUS" } ] }, { "start" : 27, "end" : 106, "hmmStart" : 226, "hmmEnd" : 305, "hmmLength" : 378, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 16, "envelopeEnd" : 111, "location-fragments" : [ { "start" : 27, "end" : 106, "dc-status" : "CONTINUOUS" } ] }, { "start" : 164, "end" : 247, "hmmStart" : 224, "hmmEnd" : 303, "hmmLength" : 378, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 156, "envelopeEnd" : 247, "location-fragments" : [ { "start" : 164, "end" : 247, "dc-status" : "CONTINUOUS" } ] }, { "start" : 221, "end" : 323, "hmmStart" : 211, "hmmEnd" : 309, "hmmLength" : 378, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 219, "envelopeEnd" : 365, "location-fragments" : [ { "start" : 221, "end" : 323, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-76, "familyName" : "FAMILY NOT NAMED", "score" : 260.8, "model-ac" : "PTHR24189" }, { "signature" : { "accession" : "G3DSA:1.25.40.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3, "end" : 158, "hmmStart" : 22, "hmmEnd" : 145, "hmmLength" : 169, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.4E-34, "score" : 121.0, "envelopeStart" : 3, "envelopeEnd" : 159, "postProcessed" : true, "location-fragments" : [ { "start" : 3, "end" : 158, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.2E-73, "score" : 246.0, "model-ac" : "3zu7B00" }, { "signature" : { "accession" : "PS50225", "name" : "SOCS", "description" : "SOCS box domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001496", "name" : "SOCS_box", "description" : "SOCS box domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Neddylation", "databaseName" : "Reactome", "id" : "R-HSA-8951664" } ] } }, "locations" : [ { "start" : 413, "end" : 460, "score" : 11.25, "alignment" : "-----LkVATAPLSLRHQARLSIRKHMGnklITRVEALPIPTVLHRYLIYDFY-", "location-fragments" : [ { "start" : 413, "end" : 460, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50225" }, { "signature" : { "accession" : "PF00023", "name" : "Ank", "description" : "Ankyrin repeat", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 256, "end" : 282, "hmmStart" : 4, "hmmEnd" : 30, "hmmLength" : 33, "hmmBounds" : "INCOMPLETE", "evalue" : 0.031, "score" : 14.7, "envelopeStart" : 256, "envelopeEnd" : 284, "postProcessed" : true, "location-fragments" : [ { "start" : 256, "end" : 282, "dc-status" : "CONTINUOUS" } ] }, { "start" : 122, "end" : 147, "hmmStart" : 5, "hmmEnd" : 30, "hmmLength" : 33, "hmmBounds" : "INCOMPLETE", "evalue" : 0.0067, "score" : 16.8, "envelopeStart" : 122, "envelopeEnd" : 148, "postProcessed" : true, "location-fragments" : [ { "start" : 122, "end" : 147, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-36, "score" : 121.9, "model-ac" : "PF00023" }, { "signature" : { "accession" : "SSF48403", "name" : "Ankyrin repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036770", "name" : "Ankyrin_rpt-contain_sf", "description" : "Ankyrin repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 27, "end" : 279, "hmmLength" : 291, "location-fragments" : [ { "start" : 27, "end" : 279, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.68E-52, "model-ac" : "0049331" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 253, "end" : 285, "score" : 10.927, "alignment" : "AKPTPLDLAILKGDISLVKMLLVSGANVNSNSP", "location-fragments" : [ { "start" : 253, "end" : 285, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "SSF158235", "name" : "SOCS box-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036036", "name" : "SOCS_box-like_dom_sf", "description" : "SOCS box-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "intracellular signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0035556" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 415, "end" : 457, "hmmLength" : 50, "location-fragments" : [ { "start" : 415, "end" : 457, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.35E-6, "model-ac" : "0053768" }, { "signature" : { "accession" : "G3DSA:1.10.750.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 421, "end" : 457, "hmmStart" : 2, "hmmEnd" : 38, "hmmLength" : 39, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-7, "score" : 33.2, "envelopeStart" : 421, "envelopeEnd" : 457, "postProcessed" : true, "location-fragments" : [ { "start" : 421, "end" : 457, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-8, "score" : 34.6, "model-ac" : "3zkjA02" }, { "signature" : { "accession" : "SM00248", "name" : "ANK_2a", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 286, "end" : 318, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 83.0, "score" : 12.0, "location-fragments" : [ { "start" : 286, "end" : 318, "dc-status" : "CONTINUOUS" } ] }, { "start" : 118, "end" : 147, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 0.0074, "score" : 25.5, "location-fragments" : [ { "start" : 118, "end" : 147, "dc-status" : "CONTINUOUS" } ] }, { "start" : 253, "end" : 282, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 0.017, "score" : 24.3, "location-fragments" : [ { "start" : 253, "end" : 282, "dc-status" : "CONTINUOUS" } ] }, { "start" : 76, "end" : 105, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 0.0025, "score" : 27.1, "location-fragments" : [ { "start" : 76, "end" : 105, "dc-status" : "CONTINUOUS" } ] }, { "start" : 182, "end" : 212, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 2.2, "score" : 17.3, "location-fragments" : [ { "start" : 182, "end" : 212, "dc-status" : "CONTINUOUS" } ] }, { "start" : 219, "end" : 248, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-4, "score" : 31.5, "location-fragments" : [ { "start" : 219, "end" : 248, "dc-status" : "CONTINUOUS" } ] }, { "start" : 43, "end" : 72, "hmmStart" : 1, "hmmEnd" : 30, "hmmLength" : 30, "hmmBounds" : "COMPLETE", "evalue" : 0.007, "score" : 25.6, "location-fragments" : [ { "start" : 43, "end" : 72, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-44, "score" : 163.3, "model-ac" : "SM00248" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 76, "end" : 108, "score" : 13.037, "alignment" : "SGYSALHLSAEHGYTELVALLLAQGAQVDYRED", "location-fragments" : [ { "start" : 76, "end" : 108, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "SM00969", "name" : "SOCS_box_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001496", "name" : "SOCS_box", "description" : "SOCS box domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Neddylation", "databaseName" : "Reactome", "id" : "R-HSA-8951664" } ] } }, "locations" : [ { "start" : 419, "end" : 458, "hmmStart" : 1, "hmmEnd" : 49, "hmmLength" : 49, "hmmBounds" : "COMPLETE", "evalue" : 3.8E-9, "score" : 46.4, "location-fragments" : [ { "start" : 419, "end" : 458, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-9, "score" : 46.4, "model-ac" : "SM00969" }, { "signature" : { "accession" : "PF07525", "name" : "SOCS_box", "description" : "SOCS box", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001496", "name" : "SOCS_box", "description" : "SOCS box domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Neddylation", "databaseName" : "Reactome", "id" : "R-HSA-8951664" } ] } }, "locations" : [ { "start" : 419, "end" : 457, "hmmStart" : 1, "hmmEnd" : 34, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 6.1E-11, "score" : 42.5, "envelopeStart" : 419, "envelopeEnd" : 457, "postProcessed" : true, "location-fragments" : [ { "start" : 419, "end" : 457, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.1E-11, "score" : 42.5, "model-ac" : "PF07525" }, { "signature" : { "accession" : "cd03587", "name" : "SOCS", "description" : "SOCS", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 419, "end" : 457, "sites" : [ { "description" : "elongin B/C interaction", "numLocations" : 8, "siteLocations" : [ { "start" : 439, "end" : 439, "residue" : "I" }, { "start" : 419, "end" : 419, "residue" : "P" }, { "start" : 445, "end" : 445, "residue" : "L" }, { "start" : 422, "end" : 422, "residue" : "L" }, { "start" : 423, "end" : 423, "residue" : "R" }, { "start" : 421, "end" : 421, "residue" : "S" }, { "start" : 429, "end" : 429, "residue" : "S" }, { "start" : 420, "end" : 420, "residue" : "L" } ] } ], "evalue" : 2.85908E-9, "score" : 50.5465, "location-fragments" : [ { "start" : 419, "end" : 457, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd03587" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 43, "end" : 75, "score" : 12.716, "alignment" : "QGLRPLHYAVWQRYPEAVRLLLIRGGDVNARDE", "location-fragments" : [ { "start" : 43, "end" : 75, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 182, "end" : 215, "score" : 9.644, "alignment" : "AGLTPLMKAARLPQGMdSVLLLISYGADVNAMTD", "location-fragments" : [ { "start" : 182, "end" : 215, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" }, { "signature" : { "accession" : "PS50088", "name" : "ANK_REPEAT", "description" : "Ankyrin repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002110", "name" : "Ankyrin_rpt", "description" : "Ankyrin repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 219, "end" : 251, "score" : 11.808, "alignment" : "DYRTVLHYAVLSGNNAIVNLLLKQGAKLNFTTD", "location-fragments" : [ { "start" : 219, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50088" } ], "xref" : [ { "name" : "XP_018910552.1 PREDICTED: ankyrin repeat and SOCS box protein 14-like [Bemisia tabaci]", "id" : "XP_018910552.1" } ] },{ "sequence" : "MSESGDSTSKFDPLNLDFSEIDDEEYNIPAVEETPTLESILNNDQNSLMSEDELSDYLAAENQGFGTGGCGSDTASISSFGSLKDTPSKTGLFNFTESRHYDHILRHIILKAISSQLKSACERVNAGRPTVMAVSSMIAVGTSHGLVLVFDSAQTLRWCHEGNEEQGSVSALDFNHNCSRLLIGYARGLILMCDVADGKVLRTMNQVHTPATAVLHVKFTDNPNLAVCSDSGGSVFELSFKRTLGIRSVDSRCIFSGSRGEVCCIEPLRLKALTTHPLHGSILVAMATLSKVILVCIRPNTRLLLTHSVSASPANLPLLTWQFVVIQLNDSSHVIDPVLAFARDSTIHFYHINVLASGRIHCTVLEQLNLGYSLLACHWLNARILATVDTQERFHLIDIRSQEELETLDLSCVSLVYNSSHFKGLCTGGNVSKAMALAGERACYNTIKSFGNQVLFLGMRSFHVISTRSWLERLNNLLEQNRYAAALRLGIDFLEERGKGVLGLSGHRKQRKKLIWQKVHEMLTTYINAVLHDNNALMYQENLPVIIEHCIHLQCEDLLFQQVWNGVEHSTVPRNIFLQSIEGFIQDGKIRNVSPAIMQKLVEYLEMTHRWQAMEECIVNVNVSSLDIEQVLQQCRSHQLYDALISVWNQAMNDYTTPLQELLPQLQRMLSSDGDRSEEAIRLGNKCLVYISCCLSGRGYPNGDIEESKCATVRSRVFQFLCSQHTINADESEETYPYLRLFLDFNTKEFLNALSMAFQDSYLSVQLLQRLVDILISITLHENSSKSRQVGWLFSWLAKEIMRPNCSLRLDLNLFEQVLEILVSSNDEQCTPEEKEQILLQLISTGALKHIPEERILQLAQTAGYHQVCAEIYERQGNHEQVLKCHLLDDSRKPRVFDYLNVAPEKSKLQRAVSENIDTLLEVNGYKTGLFVGTHFVELTSRVVHTMTKQKQFEFLQGVMDAKAALSPPVITLYFQLLCEFEPNSAMKFIIANCDTLLTDIESCVETAQKHNLEMEEAILWEKAGSYKKSFNILFKRLQYAIRSGKDVESATEELISLILRGSSVLDPKDTWLPLLQCLVQVNSPKLMKRVLNSADLNLAAEFHLLLKHTTGSLGDYRSLIMGLFEKCVYEQEVLQIAERSHYLDLHNQLKQSLNGAKRGIPNPVICTVCNKKFQSQMLLFHCTHGYHMDCLKQPFQCVKCDSN", "md5" : "33510747d0a72fbab6629bde387e0fcd", "matches" : [ { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 122, "end" : 443, "hmmStart" : 25, "hmmEnd" : 274, "hmmLength" : 340, "hmmBounds" : "COMPLETE", "evalue" : 4.0E-12, "score" : 47.4, "envelopeStart" : 122, "envelopeEnd" : 443, "postProcessed" : true, "location-fragments" : [ { "start" : 122, "end" : 443, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-12, "score" : 48.3, "model-ac" : "2ovrB02" }, { "signature" : { "accession" : "SSF50978", "name" : "WD40 repeat-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036322", "name" : "WD40_repeat_dom_sf", "description" : "WD40-repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 137, "end" : 411, "hmmLength" : 355, "location-fragments" : [ { "start" : 137, "end" : 308, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 343, "end" : 411, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.23E-15, "model-ac" : "0048349" }, { "signature" : { "accession" : "PF12894", "name" : "ANAPC4_WD40", "description" : "Anaphase-promoting complex subunit 4 WD40 domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR024977", "name" : "Apc4_WD40_dom", "description" : "Anaphase-promoting complex subunit 4, WD40 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 137, "end" : 211, "hmmStart" : 9, "hmmEnd" : 83, "hmmLength" : 92, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-4, "score" : 21.9, "envelopeStart" : 134, "envelopeEnd" : 222, "postProcessed" : true, "location-fragments" : [ { "start" : 137, "end" : 211, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-5, "score" : 24.7, "model-ac" : "PF12894" }, { "signature" : { "accession" : "PF12816", "name" : "Vps8", "description" : "Golgi CORVET complex core vacuolar protein 8", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR025941", "name" : "Vps8_central_dom", "description" : "Vacuolar protein sorting-associated protein 8, central domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 576, "end" : 758, "hmmStart" : 1, "hmmEnd" : 198, "hmmLength" : 198, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-57, "score" : 194.7, "envelopeStart" : 576, "envelopeEnd" : 758, "postProcessed" : true, "location-fragments" : [ { "start" : 576, "end" : 758, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-59, "score" : 201.1, "model-ac" : "PF12816" }, { "signature" : { "accession" : "PTHR42968:SF11", "name" : "VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 1194, "hmmStart" : 33, "hmmEnd" : 1289, "hmmLength" : 1426, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 1203, "location-fragments" : [ { "start" : 8, "end" : 1194, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-259, "familyName" : "VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG", "score" : 866.2, "model-ac" : "PTHR42968:SF11" }, { "signature" : { "accession" : "PTHR42968", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 1194, "hmmStart" : 33, "hmmEnd" : 1289, "hmmLength" : 1426, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 1203, "location-fragments" : [ { "start" : 8, "end" : 1194, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-259, "familyName" : "VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG", "score" : 866.2, "model-ac" : "PTHR42968" }, { "signature" : { "accession" : "PS50089", "name" : "ZF_RING_2", "description" : "Zinc finger RING-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1167, "end" : 1202, "score" : 8.875, "alignment" : "CTVCNKKFQSQ-MLLFHCTHGYHMDCLKQP------FQCVKCD", "location-fragments" : [ { "start" : 1167, "end" : 1202, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50089" } ], "xref" : [ { "name" : "XP_018909739.1 PREDICTED: vacuolar protein sorting-associated protein 8 homolog [Bemisia tabaci]", "id" : "XP_018909739.1" } ] },{ "sequence" : "MIPMHVCRTRLPKQCQKQMEYHRKTVKHLLEVPQPGIAATGVSIYFYYLAYCEDAIERVCLLPKEIFHEVVRMVGSRVYVGGLPYGCREKDLEKFFKGYGRIRDILLKNGYGFVEFEDNRDAEDAVYELNGRPLMGERITVERARGTDRSRRGFGGGGRFGGGGGRYGGGRRRTPDTYGPPRRTDYRVIVENLSSRISWQDLKDFMRKAGEVSYADAHRINRNEGVVEFTSYSEMKTAIEKLDGTELNGRRIRLIEDKRKSRRSYSSSSRSRSRSRSRSRSNRNRSRSHSKSARKSRSRSRLPAKKRDSKSPSRSRSPVADKSSRSPSKKRSRSRSPAPKKHSRSSSSHSKSHSRSPVKKRSKARSPSADSDRRYSESPRKDRSASPGMKNGDRSGDED", "md5" : "c4da01f57373603b982408edcb854db0", "matches" : [ { "signature" : { "accession" : "cd12337", "name" : "RRM1_SRSF4_like", "description" : "RRM1_SRSF4_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR035585", "name" : "RRM1_SRSF4-like", "description" : "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "RNA Polymerase II Transcription Termination", "databaseName" : "Reactome", "id" : "R-HSA-73856" }, { "name" : "mRNA 3'-end processing", "databaseName" : "Reactome", "id" : "R-HSA-72187" }, { "name" : "mRNA Splicing - Major Pathway", "databaseName" : "Reactome", "id" : "R-HSA-72163" }, { "name" : "Transport of Mature mRNA derived from an Intron-Containing Transcript", "databaseName" : "Reactome", "id" : "R-HSA-159236" } ] } }, "locations" : [ { "start" : 77, "end" : 146, "sites" : [ ], "evalue" : 1.58511E-37, "score" : 128.214, "location-fragments" : [ { "start" : 77, "end" : 146, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12337" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 152, "end" : 179, "location-fragments" : [ { "start" : 152, "end" : 179, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd12600", "name" : "RRM2_SRSF4_like", "description" : "RRM2_SRSF4_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 186, "end" : 257, "sites" : [ ], "evalue" : 4.10193E-46, "score" : 150.981, "location-fragments" : [ { "start" : 186, "end" : 257, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12600" }, { "signature" : { "accession" : "PTHR23147:SF55", "name" : "SERINE/ARGININE-RICH SPLICING FACTOR 4", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 76, "end" : 337, "hmmStart" : 2, "hmmEnd" : 260, "hmmLength" : 448, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 75, "envelopeEnd" : 341, "location-fragments" : [ { "start" : 76, "end" : 337, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-89, "familyName" : "SERINE/ARGININE-RICH SPLICING FACTOR 4", "score" : 303.2, "model-ac" : "PTHR23147:SF55" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 363, "end" : 399, "location-fragments" : [ { "start" : 363, "end" : 399, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 185, "end" : 258, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 77, "hmmBounds" : "COMPLETE", "evalue" : 3.3E-24, "score" : 86.6, "envelopeStart" : 185, "envelopeEnd" : 258, "postProcessed" : true, "location-fragments" : [ { "start" : 185, "end" : 258, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-45, "score" : 153.5, "model-ac" : "1wg4A01" }, { "signature" : { "accession" : "SSF54928", "name" : "RNA-binding domain, RBD", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035979", "name" : "RBD_domain_sf", "description" : "RNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 77, "end" : 260, "hmmLength" : 183, "location-fragments" : [ { "start" : 183, "end" : 260, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 77, "end" : 156, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.15E-37, "model-ac" : "0049769" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 265, "end" : 304, "location-fragments" : [ { "start" : 265, "end" : 304, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 186, "end" : 259, "score" : 12.526, "alignment" : "YRVIVENLSSRISWQDLKDFMRKAGEVSYADAHR----INRNEGVVEFTSYSEMKTAIEKLDGTELNGRRIRLIEDKR", "location-fragments" : [ { "start" : 186, "end" : 259, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 328, "end" : 362, "location-fragments" : [ { "start" : 328, "end" : 362, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 73, "end" : 177, "hmmStart" : 14, "hmmEnd" : 109, "hmmLength" : 126, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-23, "score" : 84.7, "envelopeStart" : 73, "envelopeEnd" : 177, "postProcessed" : true, "location-fragments" : [ { "start" : 73, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-38, "score" : 132.3, "model-ac" : "4pkdB02" }, { "signature" : { "accession" : "PF00076", "name" : "RRM_1", "description" : "RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 78, "end" : 139, "hmmStart" : 1, "hmmEnd" : 69, "hmmLength" : 70, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.1E-19, "score" : 67.9, "envelopeStart" : 78, "envelopeEnd" : 140, "postProcessed" : true, "location-fragments" : [ { "start" : 78, "end" : 139, "dc-status" : "CONTINUOUS" } ] }, { "start" : 188, "end" : 253, "hmmStart" : 1, "hmmEnd" : 70, "hmmLength" : 70, "hmmBounds" : "COMPLETE", "evalue" : 4.0E-13, "score" : 49.0, "envelopeStart" : 188, "envelopeEnd" : 253, "postProcessed" : true, "location-fragments" : [ { "start" : 188, "end" : 253, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.1E-35, "score" : 118.9, "model-ac" : "PF00076" }, { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 76, "end" : 146, "score" : 18.325, "alignment" : "SRVYVGGLPYGCREKDLEKFFKGYGRIRDILL-------KNGYGFVEFEDNRDAEDAVYELNGRPLMGERITVERARG", "location-fragments" : [ { "start" : 76, "end" : 146, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" }, { "signature" : { "accession" : "PTHR23147", "name" : "SERINE/ARGININE RICH SPLICING FACTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 76, "end" : 337, "hmmStart" : 2, "hmmEnd" : 260, "hmmLength" : 448, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 75, "envelopeEnd" : 341, "location-fragments" : [ { "start" : 76, "end" : 337, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-89, "familyName" : "SERINE/ARGININE-RICH SPLICING FACTOR 4", "score" : 303.2, "model-ac" : "PTHR23147" }, { "signature" : { "accession" : "SM00360", "name" : "rrm1_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 187, "end" : 255, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 6.9E-12, "score" : 55.5, "location-fragments" : [ { "start" : 187, "end" : 255, "dc-status" : "CONTINUOUS" } ] }, { "start" : 77, "end" : 142, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-21, "score" : 87.0, "location-fragments" : [ { "start" : 77, "end" : 142, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-38, "score" : 142.5, "model-ac" : "SM00360" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 253, "end" : 399, "location-fragments" : [ { "start" : 253, "end" : 399, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910450.1 PREDICTED: serine/arginine-rich splicing factor 5-like isoform X3 [Bemisia tabaci]", "id" : "XP_018910450.1" } ] },{ "sequence" : "MTLTTAGAERGRKRPGAWPGACEHPAHLCLVCATSEDGSDRGWDPELEPARPSQERMLGEHNYEAATDVDNNLTWGFTQPPSSHLRQLSQIQQSIQGTRDSGWNYANPLGRYVELCAEDTSRCSTDVQDVLEKYFTVTSVTNNLPTQKKVTARRIAKEPIKIEEKIFKTAKVGSGQKEGFSHGENTLKPEKKVSLLGIHLLRDKKMFLLQTSNSIRKTATERYQNISKAFRLPGKMASNLRFGNSCKRMSFFPNEERRADTIGRRNNYVVSQGIPRMSQLVLARVCEAPDQ", "md5" : "22dd150fd0399b05248d47278e7da7f2", "matches" : [ ], "xref" : [ { "name" : "XP_018909655.1 PREDICTED: uncharacterized protein LOC109038873 [Bemisia tabaci]", "id" : "XP_018909655.1" }, { "name" : "XP_018909654.1 PREDICTED: uncharacterized protein LOC109038873 [Bemisia tabaci]", "id" : "XP_018909654.1" } ] },{ "sequence" : "MRILITGFGPFGRIADNPSARLAELSGHDFELIDVAYNSVDTLLAGLDPERFDVLLLIGVDSQGEVLKPELHARNWCGKKPDVKGLCPVGPIEEGSPFILNSTLWSDDLLSTVEVDPDLQPSRDAGDYLCNYVYYRALQYFPQKRVGFLHIPPFEKVPREHQVEVLGRILKQIKDSVAVSGIQPDQNGEQVDLSQPSLTTNCIEN", "md5" : "1ac3c8d2954108222b11668195c27b68", "matches" : [ { "signature" : { "accession" : "SSF53182", "name" : "Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036440", "name" : "Peptidase_C15-like_sf", "description" : "Peptidase C15, pyroglutamyl peptidase I-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "5-oxo-L-proline metabolism", "databaseName" : "MetaCyc", "id" : "PWY-7942" } ] } }, "locations" : [ { "start" : 1, "end" : 173, "hmmLength" : 220, "location-fragments" : [ { "start" : 1, "end" : 173, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.76E-32, "model-ac" : "0045701" }, { "signature" : { "accession" : "PR00706", "name" : "PYROGLUPTASE", "description" : "Pyroglutamyl peptidase I (C15) family signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000816", "name" : "Peptidase_C15", "description" : "Peptidase C15, pyroglutamyl peptidase I", "type" : "FAMILY", "goXRefs" : [ { "name" : "cytosol", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005829" }, { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "pyroglutamyl-peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016920" } ], "pathwayXRefs" : [ { "name" : "5-oxo-L-proline metabolism", "databaseName" : "MetaCyc", "id" : "PWY-7942" } ] } }, "locations" : [ { "start" : 3, "end" : 26, "pvalue" : 1.57E-8, "score" : 43.52, "motifNumber" : 1, "location-fragments" : [ { "start" : 3, "end" : 26, "dc-status" : "CONTINUOUS" } ] }, { "start" : 119, "end" : 135, "pvalue" : 2.71E-6, "score" : 43.79, "motifNumber" : 4, "location-fragments" : [ { "start" : 119, "end" : 135, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.7E-8, "graphscan" : "I..I.", "model-ac" : "PR00706" }, { "signature" : { "accession" : "PTHR23402:SF1", "name" : "RE07960P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 174, "hmmStart" : 5, "hmmEnd" : 197, "hmmLength" : 200, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 177, "location-fragments" : [ { "start" : 2, "end" : 174, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-27, "familyName" : "RE07960P", "score" : 98.4, "model-ac" : "PTHR23402:SF1" }, { "signature" : { "accession" : "PTHR23402", "name" : "PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR016125", "name" : "Peptidase_C15-like", "description" : "Peptidase C15, pyroglutamyl peptidase I-like", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "5-oxo-L-proline metabolism", "databaseName" : "MetaCyc", "id" : "PWY-7942" } ] } }, "locations" : [ { "start" : 2, "end" : 174, "hmmStart" : 5, "hmmEnd" : 197, "hmmLength" : 200, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 177, "location-fragments" : [ { "start" : 2, "end" : 174, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-27, "familyName" : "RE07960P", "score" : 98.4, "model-ac" : "PTHR23402" }, { "signature" : { "accession" : "PF01470", "name" : "Peptidase_C15", "description" : "Pyroglutamyl peptidase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR016125", "name" : "Peptidase_C15-like", "description" : "Peptidase C15, pyroglutamyl peptidase I-like", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "5-oxo-L-proline metabolism", "databaseName" : "MetaCyc", "id" : "PWY-7942" } ] } }, "locations" : [ { "start" : 1, "end" : 154, "hmmStart" : 1, "hmmEnd" : 170, "hmmLength" : 203, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.3E-10, "score" : 41.7, "envelopeStart" : 1, "envelopeEnd" : 180, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 154, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-11, "score" : 42.9, "model-ac" : "PF01470" }, { "signature" : { "accession" : "G3DSA:3.40.630.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036440", "name" : "Peptidase_C15-like_sf", "description" : "Peptidase C15, pyroglutamyl peptidase I-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "5-oxo-L-proline metabolism", "databaseName" : "MetaCyc", "id" : "PWY-7942" } ] } }, "locations" : [ { "start" : 2, "end" : 180, "hmmStart" : 2, "hmmEnd" : 175, "hmmLength" : 192, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-34, "score" : 120.6, "envelopeStart" : 2, "envelopeEnd" : 180, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 180, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-34, "score" : 120.9, "model-ac" : "2ebjA00" } ], "xref" : [ { "name" : "XP_018910172.1 PREDICTED: uncharacterized protein LOC109039227 [Bemisia tabaci]", "id" : "XP_018910172.1" } ] },{ "sequence" : "MSTNSLKSSKNGTTPEKTTDQTGTTIEPLVDKQKEDMKSGGNQVNLWLAACICNLGAWVGGNALTWSSPAVPKLEKGEFLLISEDEGSSLSSLIAFGAGFGPFLASSLVDRVGRKTTLLLTMLMFLISWVLLVVVPQLNVMYLARFISGIGVGSIYTVTPMYVAEIAEVSVRGALLSIMQFFLVGGFLQEYIIGPYVSYQMLIYINLVAPAVYVLTFIWIPESPYYYLNKGKKQEATEALHWFRGKPDREFINKEIIAIEESVLEAQANKGRYIDLFRSRGSLLGLYLSCALVAFQQLSGINVILFYCQTIFEQAGASLDPSISAIIIGAVMLLASAVTPPFTKKFGMKMCLYASAVGMVLSQVVLGFYFFLDYHKYEIVSSLGWMPVTSLIAFIITYCVGIGPLPWAYMGELFPQNLKANASAVTAGFCWFLGFFITRFFSPLTKEIGLHFGFWLFAAFCVLCYAFVYFHLPDTTGKTLQEIQDMLNGKKKSPQKSSA", "md5" : "5d61a0428617f0667f15aa5503296548", "matches" : [ { "signature" : { "accession" : "TIGR00879", "name" : "TIGR00879", "description" : "SP: MFS transporter, sugar porter (SP) family", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR003663", "name" : "Sugar/inositol_transpt", "description" : "Sugar/inositol transporter", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ { "name" : "Cellular hexose transport", "databaseName" : "Reactome", "id" : "R-HSA-189200" } ] } }, "locations" : [ { "start" : 35, "end" : 483, "hmmStart" : 41, "hmmEnd" : 510, "hmmLength" : 510, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.7E-84, "score" : 281.5, "envelopeStart" : 2, "envelopeEnd" : 483, "postProcessed" : false, "location-fragments" : [ { "start" : 35, "end" : 483, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-84, "score" : 282.1, "model-ac" : "TIGR00879" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 34, "location-fragments" : [ { "start" : 1, "end" : 34, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF103473", "name" : "MFS general substrate transporter", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036259", "name" : "MFS_trans_sf", "description" : "MFS transporter superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 485, "hmmLength" : 447, "location-fragments" : [ { "start" : 37, "end" : 485, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.57E-56, "model-ac" : "0042501" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 28, "location-fragments" : [ { "start" : 1, "end" : 28, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.20.1250.20", "name" : "MFS general substrate transporter like domains", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 42, "end" : 491, "hmmStart" : 9, "hmmEnd" : 466, "hmmLength" : 470, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-103, "score" : 348.6, "envelopeStart" : 42, "envelopeEnd" : 491, "postProcessed" : true, "location-fragments" : [ { "start" : 42, "end" : 491, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-103, "score" : 349.1, "model-ac" : "4zw9A00" }, { "signature" : { "accession" : "PTHR23500:SF379", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 42, "end" : 489, "hmmStart" : 16, "hmmEnd" : 461, "hmmLength" : 468, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 27, "envelopeEnd" : 496, "location-fragments" : [ { "start" : 42, "end" : 489, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-101, "familyName" : "", "score" : 343.4, "model-ac" : "PTHR23500:SF379" }, { "signature" : { "accession" : "PS00217", "name" : "SUGAR_TRANSPORT_2", "description" : "Sugar transport proteins signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR005829", "name" : "Sugar_transporter_CS", "description" : "Sugar transporter, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 147, "end" : 172, "level" : "STRONG", "cigarAlignment" : "1M1I3M1I2M7I1M2I1M6I1M", "alignment" : "IsGIGvGSiytvtpmYvaEiaevsvR", "location-fragments" : [ { "start" : 147, "end" : 172, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00217" }, { "signature" : { "accession" : "PS50850", "name" : "MFS", "description" : "Major facilitator superfamily (MFS) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR020846", "name" : "MFS_dom", "description" : "Major facilitator superfamily domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 49, "end" : 476, "score" : 30.412, "alignment" : "AACICNLGAWVGGNALTWSSPAVPKLEKGEFLLIseDEGSSLSSLIAFGAGFGPFLASSLVDRVGRKTTLLLTMLMFLISWVLLVVVPQLNVMYLARFISGIGVGSIYTVTPMYVAEIAEVSVRGALLSI----MQFFLVGGFLQEYIIGPYVSYQMLIYINLVAPAVYVLTF-IWIPESPYYylnkgkkqeatealhwFRGKPDREFINKEIIAIEESVLEAQAnkgryidlFRSRGSLLGLYLSCALvafqQLSGINVILFYCQTIFeQAGASLDPSISAIIIG-AVMLLASAVTPPFTKKFGMKMCLYASAVGMVLSQVVLGFYFFLDYhkyeivsslgWMPVTSLIAFIITYCVGIGPLPWAYMGELFPQNLKANASAVTAGFCWFLGFFITRFFSPLTKEIGLHFGFWLFAAFCVLCYAFVYFHLPDTT", "location-fragments" : [ { "start" : 49, "end" : 476, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50850" }, { "signature" : { "accession" : "PTHR23500", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 42, "end" : 489, "hmmStart" : 16, "hmmEnd" : 461, "hmmLength" : 468, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 27, "envelopeEnd" : 496, "location-fragments" : [ { "start" : 42, "end" : 489, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-101, "familyName" : "", "score" : 343.4, "model-ac" : "PTHR23500" }, { "signature" : { "accession" : "PF00083", "name" : "Sugar_tr", "description" : "Sugar (and other) transporter", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005828", "name" : "MFS_sugar_transport-like", "description" : "Major facilitator, sugar transporter-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 90, "end" : 486, "hmmStart" : 51, "hmmEnd" : 451, "hmmLength" : 452, "hmmBounds" : "INCOMPLETE", "evalue" : 1.5E-80, "score" : 271.3, "envelopeStart" : 18, "envelopeEnd" : 487, "postProcessed" : true, "location-fragments" : [ { "start" : 90, "end" : 486, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-80, "score" : 271.5, "model-ac" : "PF00083" }, { "signature" : { "accession" : "cd17358", "name" : "MFS_GLUT6_8_Class3_like", "description" : "MFS_GLUT6_8_Class3_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 48, "end" : 482, "sites" : [ { "description" : "chemical substrate binding pocket", "numLocations" : 21, "siteLocations" : [ { "start" : 296, "end" : 296, "residue" : "Q" }, { "start" : 60, "end" : 60, "residue" : "G" }, { "start" : 64, "end" : 64, "residue" : "L" }, { "start" : 431, "end" : 431, "residue" : "W" }, { "start" : 301, "end" : 301, "residue" : "I" }, { "start" : 434, "end" : 434, "residue" : "G" }, { "start" : 297, "end" : 297, "residue" : "Q" }, { "start" : 402, "end" : 402, "residue" : "I" }, { "start" : 302, "end" : 302, "residue" : "N" }, { "start" : 306, "end" : 306, "residue" : "F" }, { "start" : 399, "end" : 399, "residue" : "C" }, { "start" : 332, "end" : 332, "residue" : "M" }, { "start" : 398, "end" : 398, "residue" : "Y" }, { "start" : 430, "end" : 430, "residue" : "C" }, { "start" : 183, "end" : 183, "residue" : "L" }, { "start" : 407, "end" : 407, "residue" : "W" }, { "start" : 180, "end" : 180, "residue" : "Q" }, { "start" : 187, "end" : 187, "residue" : "F" }, { "start" : 184, "end" : 184, "residue" : "V" }, { "start" : 305, "end" : 305, "residue" : "L" }, { "start" : 403, "end" : 403, "residue" : "G" } ] } ], "evalue" : 6.48962E-120, "score" : 356.885, "location-fragments" : [ { "start" : 48, "end" : 482, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd17358" }, { "signature" : { "accession" : "PR00171", "name" : "SUGRTRNSPORT", "description" : "Sugar transporter signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR003663", "name" : "Sugar/inositol_transpt", "description" : "Sugar/inositol transporter", "type" : "FAMILY", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "transmembrane transporter activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0022857" } ], "pathwayXRefs" : [ { "name" : "Cellular hexose transport", "databaseName" : "Reactome", "id" : "R-HSA-189200" } ] } }, "locations" : [ { "start" : 142, "end" : 161, "pvalue" : 7.75E-8, "score" : 34.79, "motifNumber" : 2, "location-fragments" : [ { "start" : 142, "end" : 161, "dc-status" : "CONTINUOUS" } ] }, { "start" : 296, "end" : 306, "pvalue" : 8.39E-6, "score" : 55.98, "motifNumber" : 3, "location-fragments" : [ { "start" : 296, "end" : 306, "dc-status" : "CONTINUOUS" } ] }, { "start" : 411, "end" : 423, "pvalue" : 2.92E-4, "score" : 30.9, "motifNumber" : 5, "location-fragments" : [ { "start" : 411, "end" : 423, "dc-status" : "CONTINUOUS" } ] }, { "start" : 388, "end" : 409, "pvalue" : 2.99E-6, "score" : 23.07, "motifNumber" : 4, "location-fragments" : [ { "start" : 388, "end" : 409, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.3E-16, "graphscan" : ".IIiI", "model-ac" : "PR00171" } ], "xref" : [ { "name" : "XP_018910394.1 PREDICTED: facilitated trehalose transporter Tret1-2 homolog [Bemisia tabaci]", "id" : "XP_018910394.1" } ] },{ "sequence" : "MSSYRSNYSSYSSSYLGSRFNTVTRTYTSSGSSRSSFSSGFTPTSSSVLSLRDKYNSLSRNSTSSVGTSRTERSSSQYDSKSGSDSYSRSYSTYKPYSSTSTESSTRASSYTPYKSYTAGSSDSSSKSTYTPWSKSYRSSVPESTYSYRSRYSSKPDAEASTEKSSTYRSSYSKPEPESNSYTSSSRDVDSRSSYSRFKSDPEPTPRKDEPEVSSYSKPSSEYKPSSYSSKNETDTSSAKDSLSVYSRYGHYGTRKSPAPSASEESKDEVKVSVTTRYTSPTPPSNSAYLRNRRAELESIYQCEIVRKSRVSKTDCQTQTDENDIYAAMKSESSEGENSEPAEPPLAASRSPVHISKSDVDVNQNIKESESFNYVRPTDITSKTVITVDSSLDPARGVHPSTEESLFAPSTFQYTSSYPNLKNSSTVSSHPNSLSVSTAILNLPNKSPTFSESDVSEKQSSPDGSLSAGKASFEKFPSPEKISEDSKNSAASKEGYKSSSSPSFGLEKAVPNQKCSLKSSSPARSPSPNSRLSRSRSPTPSYSFTISPRHHQTRSKDSSASQTNEFSVAQPEILDKSSSYHLNIPSAFQLNLEKKMSDPSRSLSRSPSPSPARGRTPENINYSSLNDPNQPSAGRLLSLAKSTSFVSKKAEYIEPVVSVPFKSTHRFSEQFSDSDISRSETSVPKIRLATYPSDSEEPYRKDTKGCSSERVPEKPIKTSESDSLSFNGPPSSTSQSPFPQEECASKPPVHPASPIVGIRVSSKERMESLRYAMMRSETPAMAFKNKSFESSSEDISDLTFDFSGKHYVINEFTENHIPNARKPLESINNEKPKEGDSFSQTEGMGQAQSQKIRKFDSGERDWWARDDTQSESFRHSSRHDSTEPPNDSSKEFSYHGAQSESMSPDGTKYPSQHHIRKFDSGERDWWAQNEPGRDAPSESPQNDIQHDSSNDSSGEFSNHEAQSRSVSPDYPKQSSQHHIRKFDSGEREWWLEDERNSGSVEGALDEDEAVENEEEEVDFWAELAAENEKHELELQHAYQLRNMDVDSSSWWIEEKTKDGDRDNQPSSGISRRTPEEDEANADEYYDAEADNSAHERNEEIYSYSIRKFDSGETPWFAEQENDDQTDKRPGSDSCQDQNQVESGIWSMETFDSTSNRPSEQFLIRTGSGHTLWYAADKSEPPVELANNERFFKIGEGERMCWIDDNTLSHTYSGSATEQPWFPDKTLSEDQVEGPYKIKRIESGEKPWWLDEDEKTDAGFDDTLCSHFRGSESRSENNVTRADLSSKASDGEEDLEPFSRVVRRVPNPTLFISELTNIDQLLGDELSFSNQCLEPTFAKIKDDGPASEDEDEIEEVSADQVKIHDNTPQTYIIEPFKGILKLDDAALQLYKDGDYSSYLDLDATISEQQEEFEGFQSNRKNSIVLRTQLSVRVHTIIEKLLNSEGSELRRALFCLKQIFQEDKDLVHEFVQNDGLSCLIKVGSDANQNYQNYILRALGQVMLYVDGMNGVIEHNETIQWLYCLVSSKFRLVVKTALKLLLVFVEYVESNCLLLIQAIHTVDKSRGSLPWSNIMKLLNEYDVTDTELLIYAMTLINKTLNRVPDLDMYYDQVDEIEKQGIQEIVQRYMSRPGTDLDFLHQLQSYEAVLNHEDGGDKTIPLKQLDDNVRTTRFSNASMISDIERRRSRRHSTGTVPLSLSVSPYNKANEDYHLKQAAEDGVGVTPALRRRLERGDRQKLLIPQEELCKSSTENYSSDDGGMKNGLKSELSNGDLKYYNGETESCLPRENTVKDLTQRLATLNSPNEESPTKLTPPPRVGEMKGIISKAIEGLAKSQSKSELKSPTNETPPMRIPEVKKSETELHWEELLASTTRALQLCDLDFTDLGSDDEKNILAPTSVANGIPPPPPPCVLPPPAPAAPLQSLTKTKKTVKLFWKEVCEDPIVMAKMNSSLIWDELTPVPVDTQKLEHLFESRTKDLITKKQHELNKNKEIIVLDPKRSNAINIGMTKLPPPRAIKTAILKMDATVMNREGIEKLLTMLPSEEERTKIQEAQTANPELPLGSAEQFLLTLASIIELPARLKLWAFKLDYENSEKEIAEPLMDLKQGMELLKANKTFRAILATLLSIGIFLNGNEVKGFQIEYLAKVPEVKDTVHKHSLLHHLCHMVMSKFPQSTDLYSEIGAVTRASKVDFDELALSIHRMEQECKASFDHLKVIVKHDGSNAMKGKMSDFLADCAERIIVLCKVHRRVINRYHKFCLWLGIPLHRVCLTKPNELCRIISEFALEYRTTRERVLQQLEKKANHRERNKTRGKMITEIGKVDTKEDRADAELRQLLGNESIDRPNSASPLHGSLPWRRQKKNSNGKGSPDQRKNGHLTDGDDELLETLVKTATKIPATRSAPRERKRIRNADRKSFIKRSRTRDNVNSPDHESSSPSP", "md5" : "df859900fb66245b56fbcb1d2dd9e44d", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 144, "end" : 294, "location-fragments" : [ { "start" : 144, "end" : 294, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51232", "name" : "GBD_FH3", "description" : "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR014768", "name" : "GBD/FH3_dom", "description" : "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1373, "end" : 1729, "score" : 20.381, "alignment" : "EPFKGILKLDDAALQLYKDGDYSS---YLDLDATISEQQEEFEGFQSNR--------KNSIVLRTQLSVRVHTIIEKLLNSEGSELRRALFCLKqifqedKDLVHEFVQNDGLSCLIKVGSDANQN---------YQNYILRALGQVMLYVDGMNGVIEHNETIQWLYCLVSSKFRLVVKTALKLLLVFVEY-VESNCLLLIQAIHTVDKS-RGSLPWSNIMKLLNEYDVTDTELLIYAMTLINKTLNRVPDLDMYYDQVDEIEKQGIQEIVQRYMSrPGTDLDFLHQLQSYeAVLNHEDGGDKTIPLKQLDD-NVRTTRFSNASMISDIERRRSRRHSTGTVPLSLSVSPYNKANEDYHLKQAAEDGVGVTPALRRRLE", "location-fragments" : [ { "start" : 1373, "end" : 1729, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51232" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 439, "end" : 467, "location-fragments" : [ { "start" : 439, "end" : 467, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 974, "end" : 1002, "location-fragments" : [ { "start" : 974, "end" : 1002, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF18382", "name" : "Formin_GBD_N", "description" : "Formin N-terminal GTPase-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR041387", "name" : "FHOD1_GBD_N", "description" : "FHOD1, N-terminal GTPase-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1378, "end" : 1427, "hmmStart" : 50, "hmmEnd" : 99, "hmmLength" : 99, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.2E-16, "score" : 59.0, "envelopeStart" : 1360, "envelopeEnd" : 1427, "postProcessed" : true, "location-fragments" : [ { "start" : 1378, "end" : 1427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-16, "score" : 60.8, "model-ac" : "PF18382" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 887, "end" : 908, "location-fragments" : [ { "start" : 887, "end" : 908, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 588, "end" : 635, "location-fragments" : [ { "start" : 588, "end" : 635, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00498", "name" : "it6_source", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR015425", "name" : "FH2_Formin", "description" : "Formin, FH2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1918, "end" : 2364, "hmmStart" : 1, "hmmEnd" : 499, "hmmLength" : 499, "hmmBounds" : "COMPLETE", "evalue" : 6.6E-59, "score" : 211.7, "location-fragments" : [ { "start" : 1918, "end" : 2364, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-59, "score" : 211.7, "model-ac" : "SM00498" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 492, "end" : 549, "location-fragments" : [ { "start" : 492, "end" : 549, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2397, "end" : 2426, "location-fragments" : [ { "start" : 2397, "end" : 2426, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 273, "end" : 289, "location-fragments" : [ { "start" : 273, "end" : 289, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 593, "end" : 635, "location-fragments" : [ { "start" : 593, "end" : 635, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1048, "end" : 1078, "location-fragments" : [ { "start" : 1048, "end" : 1078, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 192, "end" : 215, "location-fragments" : [ { "start" : 192, "end" : 215, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 934, "end" : 973, "location-fragments" : [ { "start" : 934, "end" : 973, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 216, "end" : 244, "location-fragments" : [ { "start" : 216, "end" : 244, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 910, "end" : 929, "location-fragments" : [ { "start" : 910, "end" : 929, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 318, "end" : 335, "location-fragments" : [ { "start" : 318, "end" : 335, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 813, "end" : 1015, "location-fragments" : [ { "start" : 813, "end" : 1015, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 694, "end" : 717, "location-fragments" : [ { "start" : 694, "end" : 717, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 144, "end" : 191, "location-fragments" : [ { "start" : 144, "end" : 191, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 477, "end" : 491, "location-fragments" : [ { "start" : 477, "end" : 491, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 718, "end" : 741, "location-fragments" : [ { "start" : 718, "end" : 741, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2361, "end" : 2386, "location-fragments" : [ { "start" : 2361, "end" : 2386, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR45920", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1371, "end" : 1709, "hmmStart" : 37, "hmmEnd" : 349, "hmmLength" : 1165, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1290, "envelopeEnd" : 1780, "location-fragments" : [ { "start" : 1371, "end" : 1709, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1783, "end" : 2423, "hmmStart" : 513, "hmmEnd" : 1148, "hmmLength" : 1165, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1740, "envelopeEnd" : 2432, "location-fragments" : [ { "start" : 1783, "end" : 2423, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "FAMILY NOT NAMED", "score" : 1370.6, "model-ac" : "PTHR45920" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 674, "end" : 688, "location-fragments" : [ { "start" : 674, "end" : 688, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 52, "end" : 109, "location-fragments" : [ { "start" : 52, "end" : 109, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1087, "end" : 1105, "location-fragments" : [ { "start" : 1087, "end" : 1105, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2297, "end" : 2436, "location-fragments" : [ { "start" : 2297, "end" : 2436, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51444", "name" : "FH2", "description" : "Formin homology-2 (FH2) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR015425", "name" : "FH2_Formin", "description" : "Formin, FH2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1918, "end" : 2311, "score" : 43.954, "alignment" : "PLQSLTKTKKTVKLFWKEVcEDPIVMAKMNSSLIWdELTPVPVDTQKLEHLFESR----TKDLITKKQHELNKNKEIIVLDPKRSNAINIGMTKL-PPPRAIKTAILKMDATVMNREGIEKLLTMLPSEEERTKIQEAQTANPeLPLGSAEQFLLTLASIIELPARLKLWAFKLDYENSEKEIAEPLMDLKQGMELLKANKTFRAILATLLSIGIFLNGN----EVKGFQIEYLAKVPEVKDTVHKHSLLHHLCHMVMSKFPQSTDLYSEIGAVTRASKVDFDELALSIHRMEQECKASFDHLKVIVKH--DGSNAMKGKMSDFLADCAERIIVLCKVHRRVINRYHKFCLWLGIPLHrvcLTKPNELCRIISEFALEYRTTRERVLQQLEKKANHRERNKTRGK", "location-fragments" : [ { "start" : 1918, "end" : 2311, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51444" }, { "signature" : { "accession" : "PF02181", "name" : "FH2", "description" : "Formin Homology 2 Domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR015425", "name" : "FH2_Formin", "description" : "Formin, FH2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1921, "end" : 2285, "hmmStart" : 4, "hmmEnd" : 371, "hmmLength" : 372, "hmmBounds" : "INCOMPLETE", "evalue" : 4.5E-83, "score" : 279.4, "envelopeStart" : 1918, "envelopeEnd" : 2286, "postProcessed" : true, "location-fragments" : [ { "start" : 1921, "end" : 2285, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-83, "score" : 279.4, "model-ac" : "PF02181" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 314, "end" : 359, "location-fragments" : [ { "start" : 314, "end" : 359, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2297, "end" : 2331, "location-fragments" : [ { "start" : 2297, "end" : 2331, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 439, "end" : 574, "location-fragments" : [ { "start" : 439, "end" : 574, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 557, "end" : 574, "location-fragments" : [ { "start" : 557, "end" : 574, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF101447", "name" : "Formin homology 2 domain (FH2 domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 1902, "end" : 2305, "hmmLength" : 411, "location-fragments" : [ { "start" : 1902, "end" : 2305, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-84, "model-ac" : "0044554" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 853, "end" : 886, "location-fragments" : [ { "start" : 853, "end" : 886, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.20.58.2220", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042201", "name" : "FH2_Formin_sf", "description" : "Formin, FH2 domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1983, "end" : 2315, "hmmStart" : 4, "hmmEnd" : 327, "hmmLength" : 340, "hmmBounds" : "COMPLETE", "evalue" : 5.4E-80, "score" : 270.9, "envelopeStart" : 1983, "envelopeEnd" : 2315, "postProcessed" : true, "location-fragments" : [ { "start" : 1983, "end" : 2315, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-80, "score" : 271.6, "model-ac" : "1v9dB00" }, { "signature" : { "accession" : "SSF48371", "name" : "ARM repeat", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016024", "name" : "ARM-type_fold", "description" : "Armadillo-type fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1436, "end" : 1651, "hmmLength" : 343, "location-fragments" : [ { "start" : 1436, "end" : 1651, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.84E-27, "model-ac" : "0052018" }, { "signature" : { "accession" : "G3DSA:1.25.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011989", "name" : "ARM-like", "description" : "Armadillo-like helical", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1351, "end" : 1651, "hmmStart" : 62, "hmmEnd" : 339, "hmmLength" : 339, "hmmBounds" : "COMPLETE", "evalue" : 8.7E-132, "score" : 440.9, "envelopeStart" : 1351, "envelopeEnd" : 1651, "postProcessed" : true, "location-fragments" : [ { "start" : 1351, "end" : 1651, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.7E-132, "score" : 440.9, "model-ac" : "3dadA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 668, "end" : 761, "location-fragments" : [ { "start" : 668, "end" : 761, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1043, "end" : 1139, "location-fragments" : [ { "start" : 1043, "end" : 1139, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909684.1 PREDICTED: uncharacterized protein LOC109038874 isoform X4 [Bemisia tabaci]", "id" : "XP_018909684.1" } ] },{ "sequence" : "MPSVCDDIIDAEVNGEPPPGDFQKFTDEQAEAVERKLLKRKQRLYQLIAKSDSKALREEALQHGLIDDDVRSKAWPLLLDLKDLPDWDNISGEELESHHEYNQVVLDVNRSIKRFPPSIEDSRRIAIQDELIATIVTILSRNPGLHYYQGFHDVAVTILLVVKSKMAGHIIEKISTEHLKPFLEPTMERTSSLLEYIYPILEKIDLDLCKHLDRSGVGTIFCLPWFITWFSHTIEVYETLMRLFDYFLAYDHKPGTEFLLPLYLIVSILEHWKDDILEQECEMAALHSFFYRPLDTLDFEMLLKKADRYYHSYPPESMKKAVEKRIKDKEERQRLEDLERKALRERRLRPKAPNTPWMRRLTVVAIGVVFVLSSVYYARVKSGNYRFSMAQISNILRNHSYLWTYLHNELEET", "md5" : "f7a2cb5ea5b6991a9be3c342b6097119", "matches" : [ { "signature" : { "accession" : "SSF47923", "name" : "Ypt/Rab-GAP domain of gyp1p", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035969", "name" : "Rab-GTPase_TBC_sf", "description" : "Rab-GTPase-TBC domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 61, "end" : 211, "hmmLength" : 194, "location-fragments" : [ { "start" : 61, "end" : 211, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.31E-15, "model-ac" : "0046806" }, { "signature" : { "accession" : "PF00566", "name" : "RabGAP-TBC", "description" : "Rab-GTPase-TBC domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000195", "name" : "Rab-GTPase-TBC_dom", "description" : "Rab-GTPase-TBC domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 68, "end" : 277, "hmmStart" : 1, "hmmEnd" : 215, "hmmLength" : 215, "hmmBounds" : "COMPLETE", "evalue" : 3.6E-26, "score" : 92.2, "envelopeStart" : 68, "envelopeEnd" : 277, "postProcessed" : true, "location-fragments" : [ { "start" : 68, "end" : 277, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-26, "score" : 93.1, "model-ac" : "PF00566" }, { "signature" : { "accession" : "PS50086", "name" : "TBC_RABGAP", "description" : "TBC/rab GAP domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000195", "name" : "Rab-GTPase-TBC_dom", "description" : "Rab-GTPase-TBC domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 65, "end" : 251, "score" : 22.291, "alignment" : "LIDDDVRSKAWPLLLDLKDLPDWDNISGEELESHHEYN-------QVVLDVNRSIKRFPPSIEDSRRIAIQdeLIATIVTILSRNPGLHYYQGFHDVAVTILLVVKSkmaghiiEKISTEHLKPFLEPTMER---------TSSLLEYIYPILEKIDLDLCKHLDRSGVGTI-FCLPWFITWFSHTIEvYETLMRLFDYFLAYD", "location-fragments" : [ { "start" : 65, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50086" }, { "signature" : { "accession" : "PTHR20913", "name" : "TBC1 DOMAIN FAMILY MEMBER 20/GTPASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 51, "end" : 346, "hmmStart" : 30, "hmmEnd" : 320, "hmmLength" : 382, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 24, "envelopeEnd" : 353, "location-fragments" : [ { "start" : 51, "end" : 346, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-73, "familyName" : "ZGC:63863", "score" : 249.7, "model-ac" : "PTHR20913" }, { "signature" : { "accession" : "SSF47923", "name" : "Ypt/Rab-GAP domain of gyp1p", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035969", "name" : "Rab-GTPase_TBC_sf", "description" : "Rab-GTPase-TBC domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 193, "end" : 313, "hmmLength" : 188, "location-fragments" : [ { "start" : 193, "end" : 313, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.14E-17, "model-ac" : "0037638" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 318, "end" : 341, "location-fragments" : [ { "start" : 318, "end" : 341, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "G3DSA:1.10.8.1310", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 23, "end" : 175, "hmmStart" : 11, "hmmEnd" : 157, "hmmLength" : 157, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-39, "score" : 137.5, "envelopeStart" : 23, "envelopeEnd" : 175, "postProcessed" : true, "location-fragments" : [ { "start" : 23, "end" : 175, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-39, "score" : 137.5, "model-ac" : "4hl4A01" }, { "signature" : { "accession" : "G3DSA:1.10.472.80", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 176, "end" : 316, "hmmStart" : 3, "hmmEnd" : 134, "hmmLength" : 135, "hmmBounds" : "COMPLETE", "evalue" : 3.8E-35, "score" : 122.5, "envelopeStart" : 176, "envelopeEnd" : 316, "postProcessed" : true, "location-fragments" : [ { "start" : 176, "end" : 316, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-35, "score" : 122.5, "model-ac" : "4hl4A02" }, { "signature" : { "accession" : "SM00164", "name" : "tbc_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000195", "name" : "Rab-GTPase-TBC_dom", "description" : "Rab-GTPase-TBC domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 62, "end" : 280, "hmmStart" : 1, "hmmEnd" : 310, "hmmLength" : 310, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-4, "score" : 14.5, "location-fragments" : [ { "start" : 62, "end" : 280, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-4, "score" : 14.5, "model-ac" : "SM00164" }, { "signature" : { "accession" : "PTHR20913:SF11", "name" : "ZGC:63863", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 51, "end" : 346, "hmmStart" : 30, "hmmEnd" : 320, "hmmLength" : 382, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 24, "envelopeEnd" : 353, "location-fragments" : [ { "start" : 51, "end" : 346, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-73, "familyName" : "ZGC:63863", "score" : 249.7, "model-ac" : "PTHR20913:SF11" } ], "xref" : [ { "name" : "XP_018909866.1 PREDICTED: TBC1 domain family member 20 isoform X2 [Bemisia tabaci]", "id" : "XP_018909866.1" } ] },{ "sequence" : "MSEKHNGKPVESERLDSGNHSDCENEQRDGNLSEYESQGSSEEIDVVKDSPRPEERDNSEVDSRPNNPPLLLQPTVDSSTPTIDQVSVVPGSTDLPFKCHLCDSSYAERHEALDHIRDRHSTEFQLLISKGALDANGSVNEENSHIEENSTHGEENIEQLRGKFPDYANRKVSSYVPT", "md5" : "bd6aba65b2d5960a307f2fecb43ab284", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 145, "end" : 164, "location-fragments" : [ { "start" : 145, "end" : 164, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 87, "location-fragments" : [ { "start" : 1, "end" : 87, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 63, "end" : 87, "location-fragments" : [ { "start" : 63, "end" : 87, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR46451", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 13, "end" : 172, "hmmStart" : 1293, "hmmEnd" : 1432, "hmmLength" : 1648, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 175, "location-fragments" : [ { "start" : 13, "end" : 172, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-15, "familyName" : "FAMILY NOT NAMED", "score" : 57.3, "model-ac" : "PTHR46451" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 31, "location-fragments" : [ { "start" : 1, "end" : 31, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 41, "end" : 62, "location-fragments" : [ { "start" : 41, "end" : 62, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS00028", "name" : "ZINC_FINGER_C2H2_1", "description" : "Zinc finger C2H2 type domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 99, "end" : 120, "level" : "STRONG", "cigarAlignment" : "1M2I1M3I1M8I1M4I1M", "alignment" : "ChlCdssYaerhealdHirdrH", "location-fragments" : [ { "start" : 99, "end" : 120, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00028" }, { "signature" : { "accession" : "PS50157", "name" : "ZINC_FINGER_C2H2_2", "description" : "Zinc finger C2H2 type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013087", "name" : "Znf_C2H2_type", "description" : "Zinc finger C2H2-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 97, "end" : 125, "score" : 9.12, "alignment" : "FKCHLCDSSYAERHEALDHIRdRHSTEFQ", "location-fragments" : [ { "start" : 97, "end" : 125, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50157" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 138, "end" : 164, "location-fragments" : [ { "start" : 138, "end" : 164, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910018.1 PREDICTED: uncharacterized protein LOC109039119 [Bemisia tabaci]", "id" : "XP_018910018.1" } ] },{ "sequence" : "MDSFSFFPKPPDGTHNCTPPAIDDFPRDFFTKRQRQEGAVLFHAGASIYLFIALAIVCDKYFVPAVEKICKALNMSNDVAGATFMAAATSAPELYVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGASMVVPLHWWPLTRDCIAYGITVTILICIIHDERIEWYEALILVILYGVYILVMYFDKNIQSWVRKQLKKRKGVNDQNNDQNNDQKQPTEVITIESNDKLDSIQMAQSPQQNGTIVKPNADEITPENDNESSGVLGLFSYPEKGGWFRKALWMLVLPIHAAFYITIPDCENPRFKRFYPLTFTMCIVWIGSLSYFVAWMITVVGDTLNIPDSVMGITFLAAGTSVPEAVSSVIVAKQGHGSMGISNSLGSNTFDILLCLGLPWFIKASFLPTDAGRHFVSINSRGLEYSAISLLSTLLLLYCTFALNKFYLDRKVGQACLAMYILFLILATLIELNVFFPVNLPACIRPQQ", "md5" : "f4a8541af6c50495dba4b5509da3c92b", "matches" : [ { "signature" : { "accession" : "PTHR10846", "name" : "SODIUM/POTASSIUM/CALCIUM EXCHANGER", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR004481", "name" : "K/Na/Ca-exchanger", "description" : "Sodium/potassium/calcium exchanger", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Sodium/Calcium exchangers", "databaseName" : "Reactome", "id" : "R-HSA-425561" } ] } }, "locations" : [ { "start" : 23, "end" : 466, "hmmStart" : 1, "hmmEnd" : 395, "hmmLength" : 395, "hmmBounds" : "COMPLETE", "envelopeStart" : 23, "envelopeEnd" : 466, "location-fragments" : [ { "start" : 23, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-188, "familyName" : "ZYDECO, ISOFORM F", "score" : 627.3, "model-ac" : "PTHR10846" }, { "signature" : { "accession" : "TIGR00367", "name" : "TIGR00367", "description" : "TIGR00367: K+-dependent Na+/Ca+ exchanger homolog", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR004481", "name" : "K/Na/Ca-exchanger", "description" : "Sodium/potassium/calcium exchanger", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Sodium/Calcium exchangers", "databaseName" : "Reactome", "id" : "R-HSA-425561" } ] } }, "locations" : [ { "start" : 43, "end" : 457, "hmmStart" : 3, "hmmEnd" : 312, "hmmLength" : 312, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.9E-72, "score" : 241.4, "envelopeStart" : 41, "envelopeEnd" : 457, "postProcessed" : false, "location-fragments" : [ { "start" : 43, "end" : 457, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-72, "score" : 241.8, "model-ac" : "TIGR00367" }, { "signature" : { "accession" : "G3DSA:1.20.1420.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 75, "end" : 197, "hmmStart" : 2, "hmmEnd" : 109, "hmmLength" : 221, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-27, "score" : 97.6, "envelopeStart" : 75, "envelopeEnd" : 197, "postProcessed" : true, "location-fragments" : [ { "start" : 75, "end" : 197, "dc-status" : "CONTINUOUS" } ] }, { "start" : 273, "end" : 464, "hmmStart" : 88, "hmmEnd" : 215, "hmmLength" : 221, "hmmBounds" : "COMPLETE", "evalue" : 4.8E-27, "score" : 96.7, "envelopeStart" : 273, "envelopeEnd" : 464, "postProcessed" : true, "location-fragments" : [ { "start" : 273, "end" : 464, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-55, "score" : 188.7, "model-ac" : "3v5uA02" }, { "signature" : { "accession" : "PTHR10846:SF42", "name" : "ZYDECO, ISOFORM F", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 23, "end" : 466, "hmmStart" : 1, "hmmEnd" : 395, "hmmLength" : 395, "hmmBounds" : "COMPLETE", "envelopeStart" : 23, "envelopeEnd" : 466, "location-fragments" : [ { "start" : 23, "end" : 466, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-188, "familyName" : "ZYDECO, ISOFORM F", "score" : 627.3, "model-ac" : "PTHR10846:SF42" }, { "signature" : { "accession" : "PF01699", "name" : "Na_Ca_ex", "description" : "Sodium/calcium exchanger protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004837", "name" : "NaCa_Exmemb", "description" : "Sodium/calcium exchanger membrane region", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ { "name" : "Sodium/Calcium exchangers", "databaseName" : "Reactome", "id" : "R-HSA-425561" } ] } }, "locations" : [ { "start" : 309, "end" : 462, "hmmStart" : 2, "hmmEnd" : 150, "hmmLength" : 151, "hmmBounds" : "INCOMPLETE", "evalue" : 2.1E-28, "score" : 99.2, "envelopeStart" : 308, "envelopeEnd" : 463, "postProcessed" : true, "location-fragments" : [ { "start" : 309, "end" : 462, "dc-status" : "CONTINUOUS" } ] }, { "start" : 47, "end" : 186, "hmmStart" : 5, "hmmEnd" : 150, "hmmLength" : 151, "hmmBounds" : "INCOMPLETE", "evalue" : 2.0E-24, "score" : 86.3, "envelopeStart" : 43, "envelopeEnd" : 187, "postProcessed" : true, "location-fragments" : [ { "start" : 47, "end" : 186, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-53, "score" : 179.2, "model-ac" : "PF01699" } ], "xref" : [ { "name" : "XP_018909737.1 PREDICTED: sodium/potassium/calcium exchanger 4 [Bemisia tabaci]", "id" : "XP_018909737.1" } ] },{ "sequence" : "MKASKLARRKGNNNLAWWAAGTMAAMGASSLIMLTGKALMLSILSLILSAGSAWRQFGLGGIGGRLTNCGGALIDVNGRHDVLGGRKNLMDEDQILNAYRAQVKVPPDIDDEEKMRLLAILTDLLAPPRKWARPQYLPIKRDPATDYYYLN", "md5" : "50a69ae4a2516980c44572da02cc6e9b", "matches" : [ ], "xref" : [ { "name" : "XP_018909786.1 PREDICTED: uncharacterized protein LOC109038962 [Bemisia tabaci]", "id" : "XP_018909786.1" } ] },{ "sequence" : "MKDQIASATFDTFKSRRDSITMGISPWATFFLIFGCCVLSCCALEVSTPNGKIIGFDTLRTRDGRVIHSFTGIPFAKPPIGPLRFKEPQPADPWKEPLQATNDAIMCPQADFANISNYQPLGQEDCLVLHVYSPKVDRAAKLPVMVWIHGGGFQWGAGSVYGPELLLDKDVVLVTINYRLGALGFLSTGDNAIPANLGLKDQALAIKWVHDNIVNFGGNPDLVTIFGESAGGGAVHLNLLSPLNKGRIHRVIAMSGTGYGPWAIAPPKLAKDRTKALAVLCSCPTEPSNELAECMRKVPADVLLEMGKKFNDWIVGDLVFVPTIESETENAFLPKELDKLGSEIPYMTGLTSGEGGIFASIISRGGSRFEKELKENPQYVLSKALLLKSDFPSDKHSSVAEQVRKFYFGDKPIDLDNTSQEVVNMFTDRWFLHGAVESAKKHHGDAYLYLYDHLHSISFNDVFSGGRIKGVSHADDLLDIFPLTMYFPERKYTEDDIKVSRKTLDIVTDFAKIGKLTGIGSKLQPVRRTAKTNQYLHITAEPAVKENLYSKRLEFWQSLIDAQSEVTTSSQQTRDEF", "md5" : "83d47c4d4844fdd9d237285691d0f67c", "matches" : [ { "signature" : { "accession" : "PTHR43142", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 45, "end" : 565, "hmmStart" : 28, "hmmEnd" : 563, "hmmLength" : 568, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 38, "envelopeEnd" : 569, "location-fragments" : [ { "start" : 45, "end" : 565, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-129, "familyName" : "CARBOXYLIC ESTER HYDROLASE", "score" : 436.4, "model-ac" : "PTHR43142" }, { "signature" : { "accession" : "SSF53474", "name" : "alpha/beta-Hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 560, "hmmLength" : 579, "location-fragments" : [ { "start" : 44, "end" : 560, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.92E-116, "model-ac" : "0045186" }, { "signature" : { "accession" : "PF00135", "name" : "COesterase", "description" : "Carboxylesterase family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002018", "name" : "CarbesteraseB", "description" : "Carboxylesterase, type B", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 45, "end" : 556, "hmmStart" : 4, "hmmEnd" : 515, "hmmLength" : 515, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.3E-130, "score" : 435.9, "envelopeStart" : 43, "envelopeEnd" : 556, "postProcessed" : true, "location-fragments" : [ { "start" : 45, "end" : 556, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-130, "score" : 436.2, "model-ac" : "PF00135" }, { "signature" : { "accession" : "PS00122", "name" : "CARBOXYLESTERASE_B_1", "description" : "Carboxylesterases type-B serine active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019826", "name" : "Carboxylesterase_B_AS", "description" : "Carboxylesterase type B, active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 216, "end" : 231, "level" : "STRONG", "cigarAlignment" : "3M4I1M1I1M1I1M1I3M", "alignment" : "FGGnpdlVtIfGeSAG", "location-fragments" : [ { "start" : 216, "end" : 231, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00122" }, { "signature" : { "accession" : "G3DSA:3.40.50.1820", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 38, "end" : 566, "hmmStart" : 40, "hmmEnd" : 571, "hmmLength" : 577, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-145, "score" : 488.3, "envelopeStart" : 38, "envelopeEnd" : 566, "postProcessed" : true, "location-fragments" : [ { "start" : 38, "end" : 566, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-145, "score" : 488.7, "model-ac" : "5ch5A00" }, { "signature" : { "accession" : "PTHR43142:SF1", "name" : "CARBOXYLIC ESTER HYDROLASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 45, "end" : 565, "hmmStart" : 28, "hmmEnd" : 563, "hmmLength" : 568, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 38, "envelopeEnd" : 569, "location-fragments" : [ { "start" : 45, "end" : 565, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-129, "familyName" : "CARBOXYLIC ESTER HYDROLASE", "score" : 436.4, "model-ac" : "PTHR43142:SF1" } ], "xref" : [ { "name" : "XP_018910005.1 PREDICTED: esterase E4-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910005.1" } ] },{ "sequence" : "MKCTLSHRILTYLIIFILVSELVPGVQGGKNGSDGEGKKKKHWWSGIFKRKKDPTDTREKVIGPGGSLKIRSGDTVITSLLPNRFALKPPYRWFYALNNEGTVIHFLPPLHKWFHNVRPVLIDVRKKYKRAKLMNRGQKHGHVGKVGALVAALMFESSKKENQKQKFHFNLFWCNCKHYVEYLSLGRVEGSYKHVLFQPMDKKCPLYAPLTSDMYTTIFENKEFELHDNQERTKQVRIKLKIHGHWPAYVWDSKAGK", "md5" : "ce5696f1db047a1751bd0db518ffd803", "matches" : [ ], "xref" : [ { "name" : "XP_018910211.1 PREDICTED: uncharacterized protein LOC109039254 [Bemisia tabaci]", "id" : "XP_018910211.1" } ] },{ "sequence" : "MSYGRPPPRIEGMVSLKVDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYSRESRGFAFVRFYDKRDAEDALDAMDGRLLDGRELRVQMARYGRPSSPYRHRRGRRSRSRGRRYSRSHSGSRSRSSDSKSSRGKSRSKSPKHSRSRSRSHS", "md5" : "bf6e3c05743ca040a58192fc1fd70ceb", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 135, "end" : 151, "location-fragments" : [ { "start" : 135, "end" : 151, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00076", "name" : "RRM_1", "description" : "RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 17, "end" : 86, "hmmStart" : 2, "hmmEnd" : 70, "hmmLength" : 70, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 6.9E-21, "score" : 73.9, "envelopeStart" : 16, "envelopeEnd" : 86, "postProcessed" : true, "location-fragments" : [ { "start" : 17, "end" : 86, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.2E-21, "score" : 74.3, "model-ac" : "PF00076" }, { "signature" : { "accession" : "SM00360", "name" : "rrm1_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 15, "end" : 88, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-26, "score" : 102.4, "location-fragments" : [ { "start" : 15, "end" : 88, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-26, "score" : 102.4, "model-ac" : "SM00360" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 120, "end" : 134, "location-fragments" : [ { "start" : 120, "end" : 134, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 11, "end" : 150, "hmmStart" : 15, "hmmEnd" : 113, "hmmLength" : 126, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-29, "score" : 103.0, "envelopeStart" : 11, "envelopeEnd" : 150, "postProcessed" : true, "location-fragments" : [ { "start" : 11, "end" : 150, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-29, "score" : 104.6, "model-ac" : "4pkdB02" }, { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 92, "score" : 19.4, "alignment" : "VSLKVDNLTYRTTPEDLRRVFERCGEVGDIYIPRDrYSRESRGFAFVRFYDKRDAEDALDAMDGRLLDGRELRVQMARY", "location-fragments" : [ { "start" : 14, "end" : 92, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 96, "end" : 119, "location-fragments" : [ { "start" : 96, "end" : 119, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR23147", "name" : "SERINE/ARGININE RICH SPLICING FACTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 150, "hmmStart" : 1, "hmmEnd" : 149, "hmmLength" : 287, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 151, "location-fragments" : [ { "start" : 1, "end" : 150, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-50, "familyName" : "SERINE/ARGININE-RICH SPLICING FACTOR 8", "score" : 175.1, "model-ac" : "PTHR23147" }, { "signature" : { "accession" : "PTHR23147:SF14", "name" : "SERINE/ARGININE-RICH SPLICING FACTOR 8", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 150, "hmmStart" : 1, "hmmEnd" : 149, "hmmLength" : 287, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 151, "location-fragments" : [ { "start" : 1, "end" : 150, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-50, "familyName" : "SERINE/ARGININE-RICH SPLICING FACTOR 8", "score" : 175.1, "model-ac" : "PTHR23147:SF14" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 89, "end" : 151, "location-fragments" : [ { "start" : 89, "end" : 151, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd12311", "name" : "RRM_SRSF2_SRSF8", "description" : "RRM_SRSF2_SRSF8", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 88, "sites" : [ ], "evalue" : 2.49232E-42, "score" : 133.19, "location-fragments" : [ { "start" : 16, "end" : 88, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12311" }, { "signature" : { "accession" : "SSF54928", "name" : "RNA-binding domain, RBD", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035979", "name" : "RBD_domain_sf", "description" : "RNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 121, "hmmLength" : 146, "location-fragments" : [ { "start" : 6, "end" : 121, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.03E-33, "model-ac" : "0047108" } ], "xref" : [ { "name" : "XP_018910517.1 PREDICTED: serine/arginine-rich splicing factor 2 isoform X2 [Bemisia tabaci]", "id" : "XP_018910517.1" } ] },{ "sequence" : "MRGSSSELLLDPQQELRKRKLLELAASSKGAKKQKRTCRQRAWFYSTSFLVMTSVSAGSSLLFLVPLYVDPAISTLVADFAPEPVTCTTVRREELLGIFNCSWSSCREGCTSDMYKCSHIYVAYTDHNDTRTEDAVLLVNIKGCGYPPEVKCANFTEDYGQEGAQFPCYYSRQNRTVVMAEYDRERQVRIIRHFFGLPFLVCFITSVALCIMHCRCSATDPPRTVRRVRVHNDASDGSISNRVERMRRSETEELEGAERGPL", "md5" : "02735a1c2fda36880bbec36013292475", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 239, "end" : 262, "location-fragments" : [ { "start" : 239, "end" : 262, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF16972", "name" : "TipE", "description" : "Na+ channel auxiliary subunit TipE", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR031578", "name" : "TipE", "description" : "Na+ channel auxiliary subunit TipE", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 34, "end" : 126, "hmmStart" : 6, "hmmEnd" : 98, "hmmLength" : 486, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-26, "score" : 93.6, "envelopeStart" : 30, "envelopeEnd" : 136, "postProcessed" : true, "location-fragments" : [ { "start" : 34, "end" : 126, "dc-status" : "CONTINUOUS" } ] }, { "start" : 135, "end" : 207, "hmmStart" : 236, "hmmEnd" : 307, "hmmLength" : 486, "hmmBounds" : "INCOMPLETE", "evalue" : 2.1E-11, "score" : 43.7, "envelopeStart" : 132, "envelopeEnd" : 214, "postProcessed" : true, "location-fragments" : [ { "start" : 135, "end" : 207, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-39, "score" : 137.1, "model-ac" : "PF16972" }, { "signature" : { "accession" : "PTHR12335:SF4", "name" : "TIPE HOMOLOG 1, ISOFORM B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 248, "hmmStart" : 1, "hmmEnd" : 270, "hmmLength" : 280, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 256, "location-fragments" : [ { "start" : 1, "end" : 248, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-109, "familyName" : "TIPE HOMOLOG 1, ISOFORM B", "score" : 368.0, "model-ac" : "PTHR12335:SF4" }, { "signature" : { "accession" : "PTHR12335", "name" : "TIPE PROTEIN TEMPERATURE-INDUCED PARALYTIC E", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR031578", "name" : "TipE", "description" : "Na+ channel auxiliary subunit TipE", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 248, "hmmStart" : 1, "hmmEnd" : 270, "hmmLength" : 280, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 256, "location-fragments" : [ { "start" : 1, "end" : 248, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-109, "familyName" : "TIPE HOMOLOG 1, ISOFORM B", "score" : 368.0, "model-ac" : "PTHR12335" } ], "xref" : [ { "name" : "XP_018910350.1 PREDICTED: protein tipE isoform X1 [Bemisia tabaci]", "id" : "XP_018910350.1" } ] },{ "sequence" : "MGSSRPRRSRGFRVTSANPAPVAGVNYYWAAMLNVINEDPCWALRDQPADDHAANQNCGRAATWYARRDENERVNCKFPTDPKCRLYGRFFRCTVKIQRSPLNPWCLLGHSQRVVLLTYCTAPLHAANVPNAPHAMPQGFAAAAGGQFHVG", "md5" : "0c2353e0689f79147bdc27b7dd8d68bc", "matches" : [ ], "xref" : [ { "name" : "XP_018909970.1 PREDICTED: uncharacterized protein LOC109039085 [Bemisia tabaci]", "id" : "XP_018909970.1" } ] },{ "sequence" : "MALFSTKHPKNDWNSKSCFDSQKAQSFFKGRRRYNKPPMKTSTHFLCFPLVTDTSVPQLAASLKYFRQIATKPSVSTSLSLDENHSQSEKIFTSQKADDVANIVDVETNSLNSDTTFSQPHLGPNPDLQILPSLAFRPAGTFHLTLGVMDLSSKESMSQALELLQSLDYANILKGVLLQQEKVQPEHVTDKDGNTDSQPEQCLCPDDINKGQLRLQQPTSSSKVAVEENHPTPFSKNNPLRITLTGLSTFPSPKKSCVFYAKPTSSPSSSFPLLKFSQAICKEFRNAGFITETRPLVLHATIANMRYAIQAKGGRKSEGKRGKDKWADGQCDARELIKCFNHYGGDVGEYKKKASQDKDQTNEFLWAEDIELNKVAICKMGAQKSEDEVLGLVYPPVGEKFIFS", "md5" : "d2fd927c7daaaa72862f483a2e956f5b", "matches" : [ { "signature" : { "accession" : "PTHR13360:SF1", "name" : "ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 30, "end" : 386, "hmmStart" : 137, "hmmEnd" : 357, "hmmLength" : 371, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 11, "envelopeEnd" : 398, "location-fragments" : [ { "start" : 30, "end" : 386, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-34, "familyName" : "ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1", "score" : 120.8, "model-ac" : "PTHR13360:SF1" }, { "signature" : { "accession" : "SSF55144", "name" : "LigT-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009097", "name" : "Cyclic_Pdiesterase", "description" : "Cyclic phosphodiesterase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 233, "end" : 305, "hmmLength" : 183, "location-fragments" : [ { "start" : 233, "end" : 305, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.73E-6, "model-ac" : "0039208" }, { "signature" : { "accession" : "PF10469", "name" : "AKAP7_NLS", "description" : "AKAP7 2'5' RNA ligase-like domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR019510", "name" : "Kinase-A_anchor_nucl_local_sig", "description" : "Protein kinase A anchor protein, nuclear localisation signal domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 43, "end" : 350, "hmmStart" : 2, "hmmEnd" : 160, "hmmLength" : 207, "hmmBounds" : "INCOMPLETE", "evalue" : 3.8E-18, "score" : 66.2, "envelopeStart" : 42, "envelopeEnd" : 389, "postProcessed" : true, "location-fragments" : [ { "start" : 43, "end" : 350, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.2E-19, "score" : 68.3, "model-ac" : "PF10469" }, { "signature" : { "accession" : "PTHR13360", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR009210", "name" : "ASCC1", "description" : "Activating signal cointegrator 1 complex subunit 1", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "ALKBH3 mediated reversal of alkylation damage", "databaseName" : "Reactome", "id" : "R-HSA-112126" } ] } }, "locations" : [ { "start" : 30, "end" : 386, "hmmStart" : 137, "hmmEnd" : 357, "hmmLength" : 371, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 11, "envelopeEnd" : 398, "location-fragments" : [ { "start" : 30, "end" : 386, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-34, "familyName" : "ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1", "score" : 120.8, "model-ac" : "PTHR13360" } ], "xref" : [ { "name" : "XP_018910434.1 PREDICTED: uncharacterized protein LOC109039406 isoform X2 [Bemisia tabaci]", "id" : "XP_018910434.1" } ] },{ "sequence" : "MALQLIVQFLLALAVLNYVDSNLGDYQRYVEVKKYYTKKHKYNDGVVRLVNGRTAAEGNVEVFHDGRWGSVCDDEFDEAEARVVCRQLGYRDYQRVTRDSYFGQARKKFWIDDVFCGGSEYELAQCKFSGWGNHDCTPQEAAGVVCQQTNDVKSNWTTNYSTKKSSYSSYSYKQRIQDMTGGHLSIRLTGGRVREEGQVEIRVGYSDWGVICGDGWSLREANVVCRQLGLGHATYAAHGHFYSRYSHNVLLTDVECRGDEASLMYCTHTKSPKTCTNHRNGGAGVICTREMADLVIDAGEIERSAYLQDRSLHSLQCAMEENCLASSAYRIKSSRYDWYSQTRRLLRFTARIVNTGTADFRPAVPKHLWQFHQCHMHFHSMEVFATFDVFDGSGRKVAEGHKASFCLEDNQCLRGTHPEYACANFGEQGISVNCTDIYRHDIDCQWVDITDLKPGHYTLRVAVNPEFKVGEMSFENNAADCALYYSESSARVYNCRLTRP", "md5" : "ad81752f5339ced8ebace87ce3d23478", "matches" : [ { "signature" : { "accession" : "PF01186", "name" : "Lysyl_oxidase", "description" : "Lysyl oxidase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001695", "name" : "Lysyl_oxidase", "description" : "Lysyl oxidase", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016641" }, { "name" : "copper ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005507" } ], "pathwayXRefs" : [ { "name" : "Elastic fibre formation", "databaseName" : "Reactome", "id" : "R-HSA-1566948" }, { "name" : "Crosslinking of collagen fibrils", "databaseName" : "Reactome", "id" : "R-HSA-2243919" } ] } }, "locations" : [ { "start" : 293, "end" : 496, "hmmStart" : 2, "hmmEnd" : 201, "hmmLength" : 202, "hmmBounds" : "INCOMPLETE", "evalue" : 2.1E-96, "score" : 321.4, "envelopeStart" : 292, "envelopeEnd" : 497, "postProcessed" : true, "location-fragments" : [ { "start" : 293, "end" : 496, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.7E-97, "score" : 322.5, "model-ac" : "PF01186" }, { "signature" : { "accession" : "SSF56487", "name" : "SRCR-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036772", "name" : "SRCR-like_dom_sf", "description" : "SRCR-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 46, "end" : 149, "hmmLength" : 116, "location-fragments" : [ { "start" : 46, "end" : 149, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.62E-36, "model-ac" : "0035772" }, { "signature" : { "accession" : "SM00202", "name" : "SR_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR017448", "name" : "SRCR-like_dom", "description" : "SRCR-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 47, "end" : 147, "hmmStart" : 1, "hmmEnd" : 118, "hmmLength" : 118, "hmmBounds" : "COMPLETE", "evalue" : 6.9E-46, "score" : 168.4, "location-fragments" : [ { "start" : 47, "end" : 147, "dc-status" : "CONTINUOUS" } ] }, { "start" : 186, "end" : 288, "hmmStart" : 1, "hmmEnd" : 118, "hmmLength" : 118, "hmmBounds" : "COMPLETE", "evalue" : 5.0E-24, "score" : 95.8, "location-fragments" : [ { "start" : 186, "end" : 288, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-75, "score" : 264.3, "model-ac" : "SM00202" }, { "signature" : { "accession" : "PS50287", "name" : "SRCR_2", "description" : "SRCR domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001190", "name" : "SRCR", "description" : "SRCR domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "scavenger receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005044" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 47, "end" : 147, "score" : 29.365, "alignment" : "VRLVNGRTAAEGNVEVFHDGRWGSVCDDEFDEAEARVVCRQLGYRDYQRVTRDSYFGQARKKFWIDDVFCGGSEYELAQCKFSGWGNHDCTPQEAAGVVCQ", "location-fragments" : [ { "start" : 47, "end" : 147, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50287" }, { "signature" : { "accession" : "PR00074", "name" : "LYSYLOXIDASE", "description" : "Protein-lysine 6-oxidase precursor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001695", "name" : "Lysyl_oxidase", "description" : "Lysyl oxidase", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016641" }, { "name" : "copper ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005507" } ], "pathwayXRefs" : [ { "name" : "Elastic fibre formation", "databaseName" : "Reactome", "id" : "R-HSA-1566948" }, { "name" : "Crosslinking of collagen fibrils", "databaseName" : "Reactome", "id" : "R-HSA-2243919" } ] } }, "locations" : [ { "start" : 444, "end" : 463, "pvalue" : 9.76E-11, "score" : 67.5, "motifNumber" : 8, "location-fragments" : [ { "start" : 444, "end" : 463, "dc-status" : "CONTINUOUS" } ] }, { "start" : 301, "end" : 325, "pvalue" : 6.77E-10, "score" : 56.0, "motifNumber" : 2, "location-fragments" : [ { "start" : 301, "end" : 325, "dc-status" : "CONTINUOUS" } ] }, { "start" : 421, "end" : 443, "pvalue" : 1.72E-4, "score" : 39.13, "motifNumber" : 7, "location-fragments" : [ { "start" : 421, "end" : 443, "dc-status" : "CONTINUOUS" } ] }, { "start" : 373, "end" : 393, "pvalue" : 4.33E-7, "score" : 45.24, "motifNumber" : 5, "location-fragments" : [ { "start" : 373, "end" : 393, "dc-status" : "CONTINUOUS" } ] }, { "start" : 464, "end" : 481, "pvalue" : 1.56E-4, "score" : 38.89, "motifNumber" : 9, "location-fragments" : [ { "start" : 464, "end" : 481, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-28, "graphscan" : ".I..I.III.", "model-ac" : "PR00074" }, { "signature" : { "accession" : "G3DSA:3.10.250.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036772", "name" : "SRCR-like_dom_sf", "description" : "SRCR-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 181, "end" : 294, "hmmStart" : 9, "hmmEnd" : 111, "hmmLength" : 119, "hmmBounds" : "COMPLETE", "evalue" : 3.3E-27, "score" : 96.7, "envelopeStart" : 181, "envelopeEnd" : 294, "postProcessed" : true, "location-fragments" : [ { "start" : 181, "end" : 294, "dc-status" : "CONTINUOUS" } ] }, { "start" : 39, "end" : 154, "hmmStart" : 6, "hmmEnd" : 111, "hmmLength" : 119, "hmmBounds" : "COMPLETE", "evalue" : 7.2E-39, "score" : 134.3, "envelopeStart" : 39, "envelopeEnd" : 154, "postProcessed" : true, "location-fragments" : [ { "start" : 39, "end" : 154, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-64, "score" : 217.3, "model-ac" : "1by2A00" }, { "signature" : { "accession" : "PTHR45817:SF4", "name" : "LYSYL OXIDASE-LIKE-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 29, "end" : 499, "hmmStart" : 15, "hmmEnd" : 474, "hmmLength" : 475, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 500, "location-fragments" : [ { "start" : 29, "end" : 499, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-192, "familyName" : "LYSYL OXIDASE-LIKE-RELATED", "score" : 642.2, "model-ac" : "PTHR45817:SF4" }, { "signature" : { "accession" : "PS50287", "name" : "SRCR_2", "description" : "SRCR domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001190", "name" : "SRCR", "description" : "SRCR domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "scavenger receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005044" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 186, "end" : 288, "score" : 25.945, "alignment" : "IRLTGGRVREEGQVEIRVGYSdWGVICGDGWSLREANVVCRQLGLGHATYAAHGHFYSRYSHNVLLTDVECRGDEASLMYCT-HTKSPKTCTnhRNGGAGVICT", "location-fragments" : [ { "start" : 186, "end" : 288, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50287" }, { "signature" : { "accession" : "PTHR45817", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 29, "end" : 499, "hmmStart" : 15, "hmmEnd" : 474, "hmmLength" : 475, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 4, "envelopeEnd" : 500, "location-fragments" : [ { "start" : 29, "end" : 499, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-192, "familyName" : "LYSYL OXIDASE-LIKE-RELATED", "score" : 642.2, "model-ac" : "PTHR45817" }, { "signature" : { "accession" : "PR00258", "name" : "SPERACTRCPTR", "description" : "Speract receptor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001190", "name" : "SRCR", "description" : "SRCR domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "scavenger receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005044" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 66, "end" : 77, "pvalue" : 2.14E-5, "score" : 61.48, "motifNumber" : 2, "location-fragments" : [ { "start" : 66, "end" : 77, "dc-status" : "CONTINUOUS" } ] }, { "start" : 112, "end" : 126, "pvalue" : 5.61E-5, "score" : 47.55, "motifNumber" : 4, "location-fragments" : [ { "start" : 112, "end" : 126, "dc-status" : "CONTINUOUS" } ] }, { "start" : 81, "end" : 91, "pvalue" : 3.22E-5, "score" : 66.9, "motifNumber" : 3, "location-fragments" : [ { "start" : 81, "end" : 91, "dc-status" : "CONTINUOUS" } ] }, { "start" : 135, "end" : 147, "pvalue" : 9.17E-4, "score" : 46.73, "motifNumber" : 5, "location-fragments" : [ { "start" : 135, "end" : 147, "dc-status" : "CONTINUOUS" } ] }, { "start" : 47, "end" : 63, "pvalue" : 1.6E-7, "score" : 46.61, "motifNumber" : 1, "location-fragments" : [ { "start" : 47, "end" : 63, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-18, "graphscan" : "IIIII", "model-ac" : "PR00258" }, { "signature" : { "accession" : "PS00420", "name" : "SRCR_1", "description" : "SRCR domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR001190", "name" : "SRCR", "description" : "SRCR domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "scavenger receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005044" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 52, "end" : 89, "level" : "STRONG", "cigarAlignment" : "1M5I1M2I1M6I2M2I1M3I1M8I1M3I1M", "alignment" : "GrtaaeGnvEvfhdgrWGsvCddeFdeaearvvCrqlG", "location-fragments" : [ { "start" : 52, "end" : 89, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00420" }, { "signature" : { "accession" : "SSF56487", "name" : "SRCR-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036772", "name" : "SRCR-like_dom_sf", "description" : "SRCR-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 182, "end" : 293, "hmmLength" : 116, "location-fragments" : [ { "start" : 182, "end" : 293, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.16E-28, "model-ac" : "0035772" }, { "signature" : { "accession" : "PF00530", "name" : "SRCR", "description" : "Scavenger receptor cysteine-rich domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001190", "name" : "SRCR", "description" : "SRCR domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "scavenger receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005044" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 147, "hmmStart" : 1, "hmmEnd" : 100, "hmmLength" : 100, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-27, "score" : 95.7, "envelopeStart" : 50, "envelopeEnd" : 147, "postProcessed" : true, "location-fragments" : [ { "start" : 50, "end" : 147, "dc-status" : "CONTINUOUS" } ] }, { "start" : 190, "end" : 288, "hmmStart" : 2, "hmmEnd" : 100, "hmmLength" : 100, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.1E-23, "score" : 80.9, "envelopeStart" : 189, "envelopeEnd" : 288, "postProcessed" : true, "location-fragments" : [ { "start" : 190, "end" : 288, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-50, "score" : 169.8, "model-ac" : "PF00530" } ], "xref" : [ { "name" : "XP_018909901.1 PREDICTED: lysyl oxidase homolog 3-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909901.1" }, { "name" : "XP_018909900.1 PREDICTED: lysyl oxidase homolog 3-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909900.1" }, { "name" : "XP_018909898.1 PREDICTED: lysyl oxidase homolog 3-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909898.1" }, { "name" : "XP_018909902.1 PREDICTED: lysyl oxidase homolog 3-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909902.1" }, { "name" : "XP_018909899.1 PREDICTED: lysyl oxidase homolog 3-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909899.1" }, { "name" : "XP_018909903.1 PREDICTED: lysyl oxidase homolog 3-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909903.1" } ] },{ "sequence" : "MYPGMDRNFRRSPARLANIAARKQSPARPKSPAKSKSPARSKSPSKPKSPAKSKSPSRSRPKSPARGKSPAKKSPARKASKSPARKPKSPTKAKSEPKPSPAKKPSKKKVFPEDDYSDSETSSVSVEPMKLDPKVEAVAAEVSQLPYRRSVRQVIKQIAASGEGKLDDGIKDEVKEILKANNVRTSSKSSSPKGYEVLFKALLYLIVFPAIVTLTHLSCTRAESCKLWPVRFPQTWRYFVNLESSLIFLGFVVWQIFLSILPVGKKVSGISESLEYRLSGNGLLSAFLTLSAIGGLRYFKFPVLSVLDRPMPLITTSYAVALLVSIVLFVKGGKAAKKSLNPKGNTGNKINDFIVGRELNPRIKSFDFKLFFKRHALLTALVYNALVALKLYETHKTLNTLPVTAVTIIALQTLFILDSLFFEDNFVTTFEAQVEGVGFRSVVYYTLYPFVFINLVKYLLISKVEKSPYVLGAIVVAQLIGYLIYRASNYQKNEFRKNPLNPRASALETIPTVQGRKLIVSGLWGKLQHPNYLGQLIIEWSWAFAADFKLWVPFVSAILLTITLIYRAVVVNAHNKSVYGTSWDRYTSRVKYSLIPKVF", "md5" : "55e550a39767dec0ec04ce09e46853a6", "matches" : [ { "signature" : { "accession" : "PF01222", "name" : "ERG4_ERG24", "description" : "Ergosterol biosynthesis ERG4/ERG24 family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001171", "name" : "Ergosterol_biosynth_ERG4_ERG24", "description" : "Ergosterol biosynthesis ERG4/ERG24", "type" : "FAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "sterol biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0016126" }, { "name" : "oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016628" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 240, "end" : 599, "hmmStart" : 66, "hmmEnd" : 432, "hmmLength" : 432, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.5E-65, "score" : 221.7, "envelopeStart" : 195, "envelopeEnd" : 599, "postProcessed" : true, "location-fragments" : [ { "start" : 240, "end" : 599, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-65, "score" : 222.0, "model-ac" : "PF01222" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 36, "end" : 52, "location-fragments" : [ { "start" : 36, "end" : 52, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.20.120.1630", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 403, "end" : 599, "hmmStart" : 45, "hmmEnd" : 193, "hmmLength" : 194, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-5, "score" : 26.1, "envelopeStart" : 403, "envelopeEnd" : 599, "postProcessed" : true, "location-fragments" : [ { "start" : 403, "end" : 599, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-5, "score" : 26.1, "model-ac" : "4a2nB00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 89, "end" : 116, "location-fragments" : [ { "start" : 89, "end" : 116, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR21257:SF17", "name" : "DELTA(14)-STEROL REDUCTASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 184, "end" : 599, "hmmStart" : 41, "hmmEnd" : 467, "hmmLength" : 467, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 12, "envelopeEnd" : 599, "location-fragments" : [ { "start" : 184, "end" : 599, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-93, "familyName" : "DELTA(14)-STEROL REDUCTASE", "score" : 314.7, "model-ac" : "PTHR21257:SF17" }, { "signature" : { "accession" : "PTHR21257", "name" : "STEROL REDUCTASE/LAMIN B RECEPTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 184, "end" : 599, "hmmStart" : 41, "hmmEnd" : 467, "hmmLength" : 467, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 12, "envelopeEnd" : 599, "location-fragments" : [ { "start" : 184, "end" : 599, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-93, "familyName" : "DELTA(14)-STEROL REDUCTASE", "score" : 314.7, "model-ac" : "PTHR21257" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 53, "end" : 88, "location-fragments" : [ { "start" : 53, "end" : 88, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 128, "location-fragments" : [ { "start" : 1, "end" : 128, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910355.1 PREDICTED: delta(14)-sterol reductase-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910355.1" } ] },{ "sequence" : "MLCCGRKKGRETQVDLATSPRRQPQINNTNMGPRPKDPLPMVVQGDFRKVSGISNEIFRQIETIENELDGSIAAALASVERRGEMVVRMLDYRSMGKNAAELAKRFLSMQDAQHSVHFVEIVKRPGQTLGLYIREGNGVDRADGVFISRIALESAVYNSGCLKVGDEILAVNLVDVTRMSLDDVVIIMSIPRRLVLATRQVKGLRQAQGTPSQPRALELKVPPVVVIKKSLTREEDQDDEEDEENNHRFADLNRESKIRGRVGQSRSHLALGSLDTNGDIGSGALYYNSRPHAATLDRRMGNSDNKSWSYQPPPPPVVTQQPKPQHFQPFDKSYPNTLESLAEKVHPFNPGNGPGSSYGAGSSRYATTGRSSSRLSNRGPSMPRSGSDQHLPRVEYDYGNGLPARHSGSLLRSSLRASTGMGGSYSRSRDQYNASPSSTLLPRRQRPALDYASDTEATCSSSSRASYYYCRPSPPVSSLTRGVSFRSNSLPRHSLTSQSSGRTPLSVRFERNNLLDEGDSDGALSAPELPIARKHRGRLSSTPSVFTSDEYRAWLSRTPSTSAIYDRLRAGQQKAQRFTFSAENLPERTRQSELLASYRSSGLSALTGLSGLTSSTLDRHTLANRTTSLRRMRHLLELEAKHQADRAKIMEINPAEFLKYKMEKWNGPEPVGASGLLWVHLLAGRGLRNPSPSQTTGNRDLYCVLECDRVHKARTVVRTGDLVFDWDETFELDLVGNKQLDFLIYSWDPQYRHKLCYKGSVHLASLLRDSPIHQLALKIEPRGTLYLRLRHTSPYRTFLRQSRSATGLFGGDLEATVAREGGSIPIIVRRCVEEVERRGLDIIGLYRLCGSATKKRILREAFERNARIVDLSPDHVPDINVITGVLKDYLRELPEPLFTKCLYQMMVDALTVCLPDDPEGNAKLMFSILDCLPRINKATLVFLLDHLAMVVGASGRNKMCSGSVASCLAPVLILHSESATDPMDFMQPISVLRYLLDIWPNKSVRDSVGHPVRPSKCLLPQQPPPLPAKPVGFRQTSGPVVVASPTSDTSPEENDEQDDVVSVIQAHTDSKPSPLDTSRSDANLINSLAQSVVTSSNPENGNSIANIIERFNQTTKTSNLSAPGSPATVARGINYGQPPKLPPRNNISTLGNTTVVNSVTSSSNLFANSPSNYLKDKNILSSANNLHTTNGNNSSINELPERNGLSNGTKSGRENNPFLCDPKPPPIAARNILSEGNSDILQNNVFSNSIFQRENNISGGATSNGARLFSYSPAISSAADTATNHDASYSYTNVFAKTNPFQTENMLRINVTSSLDISSGNLPTRLSSQHSPISPGQRDVETPSSSTGTEEDSRRERGVDADQESSEEDLK", "md5" : "9e9e030be0e114d900414350694ccbd8", "matches" : [ { "signature" : { "accession" : "cd00992", "name" : "PDZ_signaling", "description" : "PDZ_signaling", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 116, "end" : 196, "sites" : [ { "description" : "protein binding site", "numLocations" : 9, "siteLocations" : [ { "start" : 185, "end" : 185, "residue" : "V" }, { "start" : 130, "end" : 130, "residue" : "G" }, { "start" : 133, "end" : 133, "residue" : "I" }, { "start" : 187, "end" : 187, "residue" : "I" }, { "start" : 131, "end" : 131, "residue" : "L" }, { "start" : 184, "end" : 184, "residue" : "V" }, { "start" : 129, "end" : 129, "residue" : "L" }, { "start" : 128, "end" : 128, "residue" : "T" }, { "start" : 188, "end" : 188, "residue" : "M" } ] } ], "evalue" : 7.83787E-15, "score" : 68.7474, "location-fragments" : [ { "start" : 116, "end" : 196, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00992" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 490, "end" : 507, "location-fragments" : [ { "start" : 490, "end" : 507, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 246, "end" : 261, "location-fragments" : [ { "start" : 246, "end" : 261, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR46150:SF3", "name" : "RHO GTPASE-ACTIVATING PROTEIN 100F", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 40, "end" : 1115, "hmmStart" : 6, "hmmEnd" : 957, "hmmLength" : 1027, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 31, "envelopeEnd" : 1358, "location-fragments" : [ { "start" : 40, "end" : 1115, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "RHO GTPASE-ACTIVATING PROTEIN 100F", "score" : 1138.1, "model-ac" : "PTHR46150:SF3" }, { "signature" : { "accession" : "SSF48350", "name" : "GTPase activation domain, GAP", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR008936", "name" : "Rho_GTPase_activation_prot", "description" : "Rho GTPase activation protein", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 808, "end" : 999, "hmmLength" : 196, "location-fragments" : [ { "start" : 808, "end" : 999, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.81E-44, "model-ac" : "0050892" }, { "signature" : { "accession" : "G3DSA:1.10.555.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR008936", "name" : "Rho_GTPase_activation_prot", "description" : "Rho GTPase activation protein", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 807, "end" : 1006, "hmmStart" : 3, "hmmEnd" : 191, "hmmLength" : 208, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-49, "score" : 170.5, "envelopeStart" : 807, "envelopeEnd" : 1006, "postProcessed" : true, "location-fragments" : [ { "start" : 807, "end" : 1006, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-50, "score" : 171.4, "model-ac" : "4u3kA00" }, { "signature" : { "accession" : "PF00620", "name" : "RhoGAP", "description" : "RhoGAP domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 825, "end" : 977, "hmmStart" : 1, "hmmEnd" : 148, "hmmLength" : 152, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 7.7E-37, "score" : 126.5, "envelopeStart" : 825, "envelopeEnd" : 981, "postProcessed" : true, "location-fragments" : [ { "start" : 825, "end" : 977, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-37, "score" : 127.6, "model-ac" : "PF00620" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 32, "location-fragments" : [ { "start" : 16, "end" : 32, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1320, "end" : 1347, "location-fragments" : [ { "start" : 1320, "end" : 1347, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:2.30.42.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036034", "name" : "PDZ_sf", "description" : "PDZ superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 104, "end" : 217, "hmmStart" : 20, "hmmEnd" : 108, "hmmLength" : 128, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-16, "score" : 61.5, "envelopeStart" : 104, "envelopeEnd" : 217, "postProcessed" : true, "location-fragments" : [ { "start" : 104, "end" : 217, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-16, "score" : 62.6, "model-ac" : "1uf1A00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 420, "end" : 455, "location-fragments" : [ { "start" : 420, "end" : 455, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 230, "end" : 261, "location-fragments" : [ { "start" : 230, "end" : 261, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1190, "end" : 1214, "location-fragments" : [ { "start" : 1190, "end" : 1214, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50106", "name" : "PDZ", "description" : "PDZ domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 118, "end" : 188, "score" : 13.692, "alignment" : "FVEIVKRPGQTLGLYIREGNGVDRADGVFISRIALESAVYNSGCLKVGDEILAVNLVDVTRMSLDDVVIIM---------------", "location-fragments" : [ { "start" : 118, "end" : 188, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50106" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1320, "end" : 1371, "location-fragments" : [ { "start" : 1320, "end" : 1371, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00228", "name" : "pdz_new", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 127, "end" : 202, "hmmStart" : 1, "hmmEnd" : 80, "hmmLength" : 80, "hmmBounds" : "COMPLETE", "evalue" : 4.7E-8, "score" : 42.7, "location-fragments" : [ { "start" : 127, "end" : 202, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.7E-8, "score" : 42.7, "model-ac" : "SM00228" }, { "signature" : { "accession" : "SM00239", "name" : "C2_3c", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000008", "name" : "C2_dom", "description" : "C2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 676, "end" : 775, "hmmStart" : 1, "hmmEnd" : 92, "hmmLength" : 92, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-4, "score" : 30.1, "location-fragments" : [ { "start" : 676, "end" : 775, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-4, "score" : 30.1, "model-ac" : "SM00239" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 37, "location-fragments" : [ { "start" : 9, "end" : 37, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:2.60.40.150", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR035892", "name" : "C2_domain_sf", "description" : "C2 domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 673, "end" : 796, "hmmStart" : 6, "hmmEnd" : 126, "hmmLength" : 143, "hmmBounds" : "COMPLETE", "evalue" : 8.7E-11, "score" : 43.9, "envelopeStart" : 673, "envelopeEnd" : 796, "postProcessed" : true, "location-fragments" : [ { "start" : 673, "end" : 796, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-11, "score" : 44.9, "model-ac" : "4npkA01" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1035, "end" : 1080, "location-fragments" : [ { "start" : 1035, "end" : 1080, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00030", "name" : "C2", "description" : "C2", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 677, "end" : 779, "sites" : [ ], "evalue" : 2.20056E-10, "score" : 57.0767, "location-fragments" : [ { "start" : 677, "end" : 779, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00030" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 420, "end" : 442, "location-fragments" : [ { "start" : 420, "end" : 442, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00324", "name" : "RhoGAP_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 822, "end" : 1000, "hmmStart" : 1, "hmmEnd" : 193, "hmmLength" : 193, "hmmBounds" : "COMPLETE", "evalue" : 5.1E-40, "score" : 148.9, "location-fragments" : [ { "start" : 822, "end" : 1000, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-40, "score" : 148.9, "model-ac" : "SM00324" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 355, "end" : 384, "location-fragments" : [ { "start" : 355, "end" : 384, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 490, "end" : 513, "location-fragments" : [ { "start" : 490, "end" : 513, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1348, "end" : 1365, "location-fragments" : [ { "start" : 1348, "end" : 1365, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR46150", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 40, "end" : 1115, "hmmStart" : 6, "hmmEnd" : 957, "hmmLength" : 1027, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 31, "envelopeEnd" : 1358, "location-fragments" : [ { "start" : 40, "end" : 1115, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "RHO GTPASE-ACTIVATING PROTEIN 100F", "score" : 1138.1, "model-ac" : "PTHR46150" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1061, "end" : 1080, "location-fragments" : [ { "start" : 1061, "end" : 1080, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF49562", "name" : "C2 domain (Calcium/lipid-binding domain, CaLB)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 674, "end" : 792, "hmmLength" : 136, "location-fragments" : [ { "start" : 674, "end" : 792, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.75E-16, "model-ac" : "0038166" }, { "signature" : { "accession" : "PF00595", "name" : "PDZ", "description" : "PDZ domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001478", "name" : "PDZ", "description" : "PDZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 122, "end" : 188, "hmmStart" : 5, "hmmEnd" : 70, "hmmLength" : 82, "hmmBounds" : "INCOMPLETE", "evalue" : 3.2E-10, "score" : 40.2, "envelopeStart" : 119, "envelopeEnd" : 196, "postProcessed" : true, "location-fragments" : [ { "start" : 122, "end" : 188, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-10, "score" : 41.4, "model-ac" : "PF00595" }, { "signature" : { "accession" : "SSF50156", "name" : "PDZ domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036034", "name" : "PDZ_sf", "description" : "PDZ superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 111, "end" : 191, "hmmLength" : 124, "location-fragments" : [ { "start" : 111, "end" : 191, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.99E-16, "model-ac" : "0050541" }, { "signature" : { "accession" : "PS50238", "name" : "RHOGAP", "description" : "Rho GTPase-activating proteins domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000198", "name" : "RhoGAP_dom", "description" : "Rho GTPase-activating protein domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" } ], "pathwayXRefs" : [ { "name" : "Rho GTPase cycle", "databaseName" : "Reactome", "id" : "R-HSA-194840" } ] } }, "locations" : [ { "start" : 811, "end" : 1003, "score" : 38.893, "alignment" : "GDLEATVAREGGSIPIIVRRCVEEVERRGLDIIGLYRLCGSATKKRILREAFERNARIVDLSPDhvpDINVITGVLKDYLRELPEPLFTKCLYQMMVDaltVCLPDDPEGNAKLMFSILDCLPRINKATLVFLLDHLAMVVGASGRNKMCSGSVASCLAPVLILHSE-SATDPMDFMQPISVLRYLLDIWPNKS", "location-fragments" : [ { "start" : 811, "end" : 1003, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50238" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1190, "end" : 1217, "location-fragments" : [ { "start" : 1190, "end" : 1217, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 296, "end" : 400, "location-fragments" : [ { "start" : 296, "end" : 400, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910339.1 PREDICTED: rho GTPase-activating protein 100F-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910339.1" } ] },{ "sequence" : "MDGENVNSNGVSETDARGDKAAGAAMFPQNGRGETKTEVTSASRGCSFCGWRFVWEGRLIKCYKDTAETVTARMASDRDAWYYNMNHKNRGIAIIFNHENFTNPKLKTRCGTKTDCENLASTLRSLRFEVYTYFDASYSKVMSVISEVRNMDHSDNDCFLMAVLSHGEQNIIHAYDSPYQPEDLWHPFTADKCPSLAGKPKLFFIQACQGDRLDPGVTLMKRTETDSGPMSYRIPVHADFLIAYSTIPGFYSWRNTQRGSWFMQALCEELKKHCYSLDLLTILTFVNRRVATDYQSNVPGNNEMDAQKQIPCITYMLTRLLKFKPK", "md5" : "7d63f008e7541dbc3aa173c10a17085f", "matches" : [ { "signature" : { "accession" : "PTHR10454", "name" : "CASPASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR002398", "name" : "Pept_C14", "description" : "Peptidase C14 family", "type" : "FAMILY", "goXRefs" : [ { "name" : "cysteine-type endopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004197" }, { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 65, "end" : 325, "hmmStart" : 15, "hmmEnd" : 271, "hmmLength" : 272, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 20, "envelopeEnd" : 326, "location-fragments" : [ { "start" : 65, "end" : 325, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-101, "familyName" : "AT03047P-RELATED", "score" : 341.1, "model-ac" : "PTHR10454" }, { "signature" : { "accession" : "PS50208", "name" : "CASPASE_P20", "description" : "Caspase family p20 domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001309", "name" : "Pept_C14_p20", "description" : "Peptidase C14, p20 domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "cysteine-type endopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004197" }, { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 89, "end" : 212, "score" : 39.066, "alignment" : "NRGIAIIFNHENFTnpKLKTRCGTKTDCENLASTLRSLRFEVYTYFDASYSKVMSVISEVRNMDHSDNDCFLMAVLSHGEQNIIHAYDS-PYQPEDLWHPFTADKCPSLAGKPKLFFIQACQGDR", "location-fragments" : [ { "start" : 89, "end" : 212, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50208" }, { "signature" : { "accession" : "PS01122", "name" : "CASPASE_CYS", "description" : "Caspase family cysteine active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR033139", "name" : "Caspase_cys_AS", "description" : "Peptidase family C14A, cysteine active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 199, "end" : 210, "level" : "STRONG", "cigarAlignment" : "12M", "alignment" : "KPKLFFIQACQG", "location-fragments" : [ { "start" : 199, "end" : 210, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01122" }, { "signature" : { "accession" : "SSF52129", "name" : "Caspase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029030", "name" : "Caspase-like_dom_sf", "description" : "Caspase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 74, "end" : 325, "hmmLength" : 256, "location-fragments" : [ { "start" : 74, "end" : 325, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.74E-91, "model-ac" : "0040830" }, { "signature" : { "accession" : "cd00032", "name" : "CASc", "description" : "CASc", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR015917", "name" : "Pept_C14A", "description" : "Peptidase C14A, caspase catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 82, "end" : 324, "sites" : [ { "description" : "substrate pocket", "numLocations" : 12, "siteLocations" : [ { "start" : 206, "end" : 206, "residue" : "Q" }, { "start" : 254, "end" : 254, "residue" : "R" }, { "start" : 213, "end" : 213, "residue" : "L" }, { "start" : 252, "end" : 252, "residue" : "S" }, { "start" : 260, "end" : 260, "residue" : "S" }, { "start" : 167, "end" : 167, "residue" : "G" }, { "start" : 253, "end" : 253, "residue" : "W" }, { "start" : 261, "end" : 261, "residue" : "W" }, { "start" : 251, "end" : 251, "residue" : "Y" }, { "start" : 109, "end" : 109, "residue" : "R" }, { "start" : 255, "end" : 255, "residue" : "N" }, { "start" : 256, "end" : 256, "residue" : "T" } ] }, { "description" : "active site", "numLocations" : 2, "siteLocations" : [ { "start" : 166, "end" : 166, "residue" : "H" }, { "start" : 208, "end" : 208, "residue" : "C" } ] }, { "description" : "proteolytic cleavage site", "numLocations" : 2, "siteLocations" : [ { "start" : 235, "end" : 235, "residue" : "P" }, { "start" : 215, "end" : 215, "residue" : "P" } ] }, { "description" : "dimer interface", "numLocations" : 15, "siteLocations" : [ { "start" : 244, "end" : 244, "residue" : "Y" }, { "start" : 247, "end" : 247, "residue" : "I" }, { "start" : 320, "end" : 320, "residue" : "L" }, { "start" : 236, "end" : 236, "residue" : "V" }, { "start" : 237, "end" : 237, "residue" : "H" }, { "start" : 314, "end" : 314, "residue" : "T" }, { "start" : 319, "end" : 319, "residue" : "R" }, { "start" : 316, "end" : 316, "residue" : "M" }, { "start" : 287, "end" : 287, "residue" : "N" }, { "start" : 214, "end" : 214, "residue" : "D" }, { "start" : 273, "end" : 273, "residue" : "H" }, { "start" : 281, "end" : 281, "residue" : "T" }, { "start" : 250, "end" : 250, "residue" : "F" }, { "start" : 308, "end" : 308, "residue" : "K" }, { "start" : 313, "end" : 313, "residue" : "I" } ] } ], "evalue" : 2.05226E-104, "score" : 303.753, "location-fragments" : [ { "start" : 82, "end" : 324, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00032" }, { "signature" : { "accession" : "PR00376", "name" : "IL1BCENZYME", "description" : "Interleukin-1B converting enzyme signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR015917", "name" : "Pept_C14A", "description" : "Peptidase C14A, caspase catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 109, "end" : 127, "pvalue" : 1.38E-5, "score" : 34.61, "motifNumber" : 2, "location-fragments" : [ { "start" : 109, "end" : 127, "dc-status" : "CONTINUOUS" } ] }, { "start" : 127, "end" : 145, "pvalue" : 0.0261, "score" : 17.38, "motifNumber" : 3, "location-fragments" : [ { "start" : 127, "end" : 145, "dc-status" : "CONTINUOUS" } ] }, { "start" : 193, "end" : 211, "pvalue" : 1.12E-11, "score" : 68.26, "motifNumber" : 5, "location-fragments" : [ { "start" : 193, "end" : 211, "dc-status" : "CONTINUOUS" } ] }, { "start" : 159, "end" : 167, "pvalue" : 6.12E-4, "score" : 48.48, "motifNumber" : 4, "location-fragments" : [ { "start" : 159, "end" : 167, "dc-status" : "CONTINUOUS" } ] }, { "start" : 89, "end" : 102, "pvalue" : 3.29E-6, "score" : 39.83, "motifNumber" : 1, "location-fragments" : [ { "start" : 89, "end" : 102, "dc-status" : "CONTINUOUS" } ] }, { "start" : 252, "end" : 263, "pvalue" : 4.82E-7, "score" : 59.34, "motifNumber" : 6, "location-fragments" : [ { "start" : 252, "end" : 263, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-27, "graphscan" : "IIiIII.", "model-ac" : "PR00376" }, { "signature" : { "accession" : "PF00656", "name" : "Peptidase_C14", "description" : "Caspase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 91, "end" : 322, "hmmStart" : 1, "hmmEnd" : 246, "hmmLength" : 247, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.3E-44, "score" : 152.3, "envelopeStart" : 91, "envelopeEnd" : 323, "postProcessed" : true, "location-fragments" : [ { "start" : 91, "end" : 322, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-44, "score" : 152.6, "model-ac" : "PF00656" }, { "signature" : { "accession" : "PS01121", "name" : "CASPASE_HIS", "description" : "Caspase family histidine active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR016129", "name" : "Caspase_his_AS", "description" : "Peptidase family C14A, His active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 153, "end" : 167, "level" : "STRONG", "cigarAlignment" : "1M4I1M2I1M1I5M", "alignment" : "HsdndCflMaVLSHG", "location-fragments" : [ { "start" : 153, "end" : 167, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01121" }, { "signature" : { "accession" : "SM00115", "name" : "caspase_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR015917", "name" : "Pept_C14A", "description" : "Peptidase C14A, caspase catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "cysteine-type peptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008234" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 82, "end" : 325, "hmmStart" : 1, "hmmEnd" : 282, "hmmLength" : 282, "hmmBounds" : "COMPLETE", "evalue" : 3.5E-112, "score" : 388.7, "location-fragments" : [ { "start" : 82, "end" : 325, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-112, "score" : 388.7, "model-ac" : "SM00115" }, { "signature" : { "accession" : "PTHR10454:SF216", "name" : "AT03047P-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 65, "end" : 325, "hmmStart" : 15, "hmmEnd" : 271, "hmmLength" : 272, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 20, "envelopeEnd" : 326, "location-fragments" : [ { "start" : 65, "end" : 325, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-101, "familyName" : "AT03047P-RELATED", "score" : 341.1, "model-ac" : "PTHR10454:SF216" }, { "signature" : { "accession" : "PS50207", "name" : "CASPASE_P10", "description" : "Caspase family p10 domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR002138", "name" : "Pept_C14_p10", "description" : "Peptidase C14, caspase non-catalytic subunit p10", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "cysteine-type endopeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004197" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 230, "end" : 325, "score" : 35.528, "alignment" : "MSYRIPVHADFLIAYSTIPGFYSWRNTQRGSWFMQALCEELKKHCYSLDLLTILTFVNRRVAtdyqSNVPGNNEMDAQKQIPCITYMLTRLLKFKP", "location-fragments" : [ { "start" : 230, "end" : 325, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50207" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 36, "location-fragments" : [ { "start" : 1, "end" : 36, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.40.50.1460", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 61, "end" : 326, "hmmStart" : 10, "hmmEnd" : 267, "hmmLength" : 272, "hmmBounds" : "COMPLETE", "evalue" : 7.9E-106, "score" : 354.6, "envelopeStart" : 61, "envelopeEnd" : 326, "postProcessed" : true, "location-fragments" : [ { "start" : 61, "end" : 326, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-106, "score" : 354.9, "model-ac" : "1m72A00" } ], "xref" : [ { "name" : "XP_018910200.1 PREDICTED: caspase-1-like isoform X3 [Bemisia tabaci]", "id" : "XP_018910200.1" } ] },{ "sequence" : "MDVFLMIRRKNLTIFTDAKDNTTVLELKRILEGILKVPPSSQRLYDKNVHVMEDSKTLQDYGLTSSVAKAQCPAALGLALKGDDGEFETFDLTPYSAPPDLPYVMKIQPTGAEQSE", "md5" : "61b06fdec025357ae9ea24617acf4cc0", "matches" : [ { "signature" : { "accession" : "PTHR13248", "name" : "TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR039049", "name" : "ELOB", "description" : "Elongin B", "type" : "FAMILY", "goXRefs" : [ { "name" : "transcription elongation from RNA polymerase II promoter", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006368" }, { "name" : "VCB complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0030891" }, { "name" : "elongin complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0070449" } ], "pathwayXRefs" : [ { "name" : "RNA Polymerase II Transcription Elongation", "databaseName" : "Reactome", "id" : "R-HSA-75955" }, { "name" : "Tat-mediated HIV elongation arrest and recovery", "databaseName" : "Reactome", "id" : "R-HSA-167243" }, { "name" : "Neddylation", "databaseName" : "Reactome", "id" : "R-HSA-8951664" }, { "name" : "HIV elongation arrest and recovery", "databaseName" : "Reactome", "id" : "R-HSA-167287" }, { "name" : "TP53 Regulates Transcription of DNA Repair Genes", "databaseName" : "Reactome", "id" : "R-HSA-6796648" }, { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" }, { "name" : "Formation of RNA Pol II elongation complex", "databaseName" : "Reactome", "id" : "R-HSA-112382" }, { "name" : "Formation of HIV elongation complex in the absence of HIV Tat", "databaseName" : "Reactome", "id" : "R-HSA-167152" }, { "name" : "Regulation of expression of SLITs and ROBOs", "databaseName" : "Reactome", "id" : "R-HSA-9010553" }, { "name" : "Pausing and recovery of HIV elongation", "databaseName" : "Reactome", "id" : "R-HSA-167290" }, { "name" : "Pausing and recovery of Tat-mediated HIV elongation", "databaseName" : "Reactome", "id" : "R-HSA-167238" }, { "name" : "Tat-mediated elongation of the HIV-1 transcript", "databaseName" : "Reactome", "id" : "R-HSA-167246" }, { "name" : "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha", "databaseName" : "Reactome", "id" : "R-HSA-1234176" }, { "name" : "Vif-mediated degradation of APOBEC3G", "databaseName" : "Reactome", "id" : "R-HSA-180585" }, { "name" : "Formation of HIV-1 elongation complex containing HIV-1 Tat", "databaseName" : "Reactome", "id" : "R-HSA-167200" }, { "name" : "RNA Polymerase II Pre-transcription Events", "databaseName" : "Reactome", "id" : "R-HSA-674695" } ] } }, "locations" : [ { "start" : 1, "end" : 113, "hmmStart" : 36, "hmmEnd" : 146, "hmmLength" : 202, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 116, "location-fragments" : [ { "start" : 1, "end" : 113, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-42, "familyName" : "TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2", "score" : 147.2, "model-ac" : "PTHR13248" }, { "signature" : { "accession" : "G3DSA:3.10.20.90", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 100, "hmmStart" : 1, "hmmEnd" : 98, "hmmLength" : 98, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-27, "score" : 96.8, "envelopeStart" : 1, "envelopeEnd" : 100, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 100, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-27, "score" : 97.0, "model-ac" : "2fnjB00" }, { "signature" : { "accession" : "SSF54236", "name" : "Ubiquitin-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029071", "name" : "Ubiquitin-like_domsf", "description" : "Ubiquitin-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 106, "hmmLength" : 106, "location-fragments" : [ { "start" : 1, "end" : 106, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.91E-22, "model-ac" : "0040559" }, { "signature" : { "accession" : "cd01788", "name" : "Ubl_ElonginB", "description" : "Ubl_ElonginB", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 104, "sites" : [ { "description" : "key conserved lysines", "numLocations" : 2, "siteLocations" : [ { "start" : 8, "end" : 8, "residue" : "R" }, { "start" : 28, "end" : 28, "residue" : "K" } ] }, { "description" : "elongin C interaction site", "numLocations" : 39, "siteLocations" : [ { "start" : 75, "end" : 75, "residue" : "A" }, { "start" : 43, "end" : 43, "residue" : "R" }, { "start" : 11, "end" : 11, "residue" : "N" }, { "start" : 100, "end" : 100, "residue" : "D" }, { "start" : 97, "end" : 97, "residue" : "A" }, { "start" : 101, "end" : 101, "residue" : "L" }, { "start" : 34, "end" : 34, "residue" : "I" }, { "start" : 16, "end" : 16, "residue" : "T" }, { "start" : 74, "end" : 74, "residue" : "A" }, { "start" : 81, "end" : 81, "residue" : "K" }, { "start" : 50, "end" : 50, "residue" : "H" }, { "start" : 60, "end" : 60, "residue" : "D" }, { "start" : 87, "end" : 87, "residue" : "F" }, { "start" : 94, "end" : 94, "residue" : "P" }, { "start" : 17, "end" : 17, "residue" : "D" }, { "start" : 62, "end" : 62, "residue" : "G" }, { "start" : 72, "end" : 72, "residue" : "C" }, { "start" : 93, "end" : 93, "residue" : "T" }, { "start" : 96, "end" : 96, "residue" : "S" }, { "start" : 14, "end" : 14, "residue" : "I" }, { "start" : 67, "end" : 67, "residue" : "V" }, { "start" : 88, "end" : 88, "residue" : "E" }, { "start" : 95, "end" : 95, "residue" : "Y" }, { "start" : 49, "end" : 49, "residue" : "V" }, { "start" : 15, "end" : 15, "residue" : "F" }, { "start" : 4, "end" : 4, "residue" : "F" }, { "start" : 48, "end" : 48, "residue" : "N" }, { "start" : 70, "end" : 70, "residue" : "A" }, { "start" : 71, "end" : 71, "residue" : "Q" }, { "start" : 73, "end" : 73, "residue" : "P" }, { "start" : 6, "end" : 6, "residue" : "M" }, { "start" : 8, "end" : 8, "residue" : "R" }, { "start" : 99, "end" : 99, "residue" : "P" }, { "start" : 45, "end" : 45, "residue" : "Y" }, { "start" : 69, "end" : 69, "residue" : "K" }, { "start" : 90, "end" : 90, "residue" : "F" }, { "start" : 12, "end" : 12, "residue" : "L" }, { "start" : 13, "end" : 13, "residue" : "T" }, { "start" : 98, "end" : 98, "residue" : "P" } ] }, { "description" : "key conserved lysine K27", "numLocations" : 1, "siteLocations" : [ { "start" : 28, "end" : 28, "residue" : "K" } ] }, { "description" : "oligomer interface", "numLocations" : 39, "siteLocations" : [ { "start" : 75, "end" : 75, "residue" : "A" }, { "start" : 43, "end" : 43, "residue" : "R" }, { "start" : 11, "end" : 11, "residue" : "N" }, { "start" : 100, "end" : 100, "residue" : "D" }, { "start" : 97, "end" : 97, "residue" : "A" }, { "start" : 101, "end" : 101, "residue" : "L" }, { "start" : 34, "end" : 34, "residue" : "I" }, { "start" : 16, "end" : 16, "residue" : "T" }, { "start" : 74, "end" : 74, "residue" : "A" }, { "start" : 81, "end" : 81, "residue" : "K" }, { "start" : 50, "end" : 50, "residue" : "H" }, { "start" : 60, "end" : 60, "residue" : "D" }, { "start" : 87, "end" : 87, "residue" : "F" }, { "start" : 94, "end" : 94, "residue" : "P" }, { "start" : 17, "end" : 17, "residue" : "D" }, { "start" : 62, "end" : 62, "residue" : "G" }, { "start" : 72, "end" : 72, "residue" : "C" }, { "start" : 93, "end" : 93, "residue" : "T" }, { "start" : 96, "end" : 96, "residue" : "S" }, { "start" : 14, "end" : 14, "residue" : "I" }, { "start" : 67, "end" : 67, "residue" : "V" }, { "start" : 88, "end" : 88, "residue" : "E" }, { "start" : 95, "end" : 95, "residue" : "Y" }, { "start" : 49, "end" : 49, "residue" : "V" }, { "start" : 15, "end" : 15, "residue" : "F" }, { "start" : 4, "end" : 4, "residue" : "F" }, { "start" : 48, "end" : 48, "residue" : "N" }, { "start" : 70, "end" : 70, "residue" : "A" }, { "start" : 71, "end" : 71, "residue" : "Q" }, { "start" : 73, "end" : 73, "residue" : "P" }, { "start" : 6, "end" : 6, "residue" : "M" }, { "start" : 8, "end" : 8, "residue" : "R" }, { "start" : 99, "end" : 99, "residue" : "P" }, { "start" : 45, "end" : 45, "residue" : "Y" }, { "start" : 69, "end" : 69, "residue" : "K" }, { "start" : 90, "end" : 90, "residue" : "F" }, { "start" : 12, "end" : 12, "residue" : "L" }, { "start" : 13, "end" : 13, "residue" : "T" }, { "start" : 98, "end" : 98, "residue" : "P" } ] } ], "evalue" : 6.78622E-55, "score" : 164.391, "location-fragments" : [ { "start" : 2, "end" : 104, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01788" }, { "signature" : { "accession" : "PS50053", "name" : "UBIQUITIN_2", "description" : "Ubiquitin domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000626", "name" : "Ubiquitin-like_dom", "description" : "Ubiquitin-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 65, "score" : 12.509, "alignment" : "MDVFLMIRRKnLTIFTDAKDNTTVLELKRILEGILKVPPSSQRLYDkNVHVMEDSKTLQDYGLTS-------------", "location-fragments" : [ { "start" : 1, "end" : 65, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50053" }, { "signature" : { "accession" : "PF00240", "name" : "ubiquitin", "description" : "Ubiquitin family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000626", "name" : "Ubiquitin-like_dom", "description" : "Ubiquitin-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 65, "hmmStart" : 10, "hmmEnd" : 61, "hmmLength" : 72, "hmmBounds" : "INCOMPLETE", "evalue" : 1.2E-5, "score" : 25.0, "envelopeStart" : 5, "envelopeEnd" : 68, "postProcessed" : true, "location-fragments" : [ { "start" : 13, "end" : 65, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.7E-6, "score" : 25.8, "model-ac" : "PF00240" } ], "xref" : [ { "name" : "XP_018910371.1 PREDICTED: transcription elongation factor B polypeptide 2 [Bemisia tabaci]", "id" : "XP_018910371.1" } ] },{ "sequence" : "MEETASSSNTKVSNDSAYSTCSNSQSRRSGSSKSHSHHSTTSSTSSGYGGHPSSSTLGSGSNDQLFPEPAKKSKVKDHKKKKIKSSNTTSSSTVPTPPTSTPTINEATSSEELSASSQVKSTPVAAELAEKSAATLECPQKTGKTREVVQDRRKLRSHPDSVLSSIINNGATPSAENESLQMAALSQTLLCFKKMKNKELHPPDLQTSNIDEEQFIRSNQKNDESFKSYVETSVKEKEFCVVVSMHDGIVLYTSSGLTDVLGFHKDMWLGRSFTDFVHPKDRIAFVSHVTSGVTKPFLDNQFSADASSSSKHNAKNSTFYCHLRCYRGLKSSGFNIIDRDVKYIACQFTLSFKEIVANSESSCFLNSPHGIFSVINVQPVFSAYTSSNEVINSPKFMTRHSANGVFCHVDSLVVSYLGYLPQDMMNHSIFNFYCSEDLPMLRDVYKEVMSEQGHLVASKPYKFKCQNGSFAVIETEWSTFINPWTKNLEFVIGQHKVIQGPADVDVTVPSKTEDSTPETDSQAELLKKEILEILQKPVNASNRVVKVQVSKRCRDLASFIETLVEEITKPETKNDTQKDANVSERDSVMLGEISPHHEYGSKVSSETPPSYTQLNYNENIQRFFQSQPKTSFSDRTSENKIMNSTPETSEGNEESSSSNPSNSKDRHNEDMEKQMVINHRAQRGKMLKVKAKPQDRVGDAHGVKRSGSHSWDNGPYRRSMKQIHGNDQPHDTNRQSNRRSVVTVTMQSSIGNAYNPPEPSSISNFTYWPMFSYNGPMLQHMDHNESVPTSVPAVMGPGMHPGLAPGMPAVMPVSTPSSLPPYYIPREQQIRPEHAGPPFPPFTYIATNQAHVMSPMIHPNWPGYSPMFYAPCPVIPPLSNLGSKSGMTPSSDFNRPVSRATSVKAEPGSARSSFILMQSDASKKGGHLSVSPNNYNSNVFPGGKDNAPGGKEESGEFSFSETGDESSYYSSFYSFLKTEEKMDDSMRSSSGDDVKKYEDELWGILNGTNDDEGKKCLRRGPTWLEGVDITPELQFRYQISTKGISDVLQADMKALAKLNQPDMVNEQLSTLYLELEGIYNSLKLEDSSSSGEEGTSNKPRKRKPFNYDKMVMIFEEEAPLPPPVTTAIPVSVTVTASGN", "md5" : "4ee999f3d6c5a65d150d80d4d838d5f5", "matches" : [ { "signature" : { "accession" : "SSF55785", "name" : "PYP-like sensor domain (PAS domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035965", "name" : "PAS-like_dom_sf", "description" : "PAS domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 394, "end" : 498, "hmmLength" : 109, "location-fragments" : [ { "start" : 394, "end" : 498, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.54E-21, "model-ac" : "0048579" }, { "signature" : { "accession" : "cd00130", "name" : "PAS", "description" : "PAS", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 393, "end" : 497, "sites" : [ { "description" : "heme pocket", "numLocations" : 7, "siteLocations" : [ { "start" : 475, "end" : 475, "residue" : "T" }, { "start" : 429, "end" : 429, "residue" : "I" }, { "start" : 444, "end" : 444, "residue" : "V" }, { "start" : 445, "end" : 445, "residue" : "Y" }, { "start" : 477, "end" : 477, "residue" : "W" }, { "start" : 441, "end" : 441, "residue" : "L" }, { "start" : 433, "end" : 433, "residue" : "Y" } ] }, { "description" : "putative active site", "numLocations" : 9, "siteLocations" : [ { "start" : 435, "end" : 435, "residue" : "S" }, { "start" : 468, "end" : 468, "residue" : "G" }, { "start" : 409, "end" : 409, "residue" : "V" }, { "start" : 463, "end" : 463, "residue" : "F" }, { "start" : 434, "end" : 434, "residue" : "C" }, { "start" : 419, "end" : 419, "residue" : "Y" }, { "start" : 413, "end" : 413, "residue" : "V" }, { "start" : 432, "end" : 432, "residue" : "F" }, { "start" : 433, "end" : 433, "residue" : "Y" } ] } ], "evalue" : 1.55479E-7, "score" : 48.7835, "location-fragments" : [ { "start" : 393, "end" : 497, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00130" }, { "signature" : { "accession" : "PS50112", "name" : "PAS", "description" : "PAS repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 401, "end" : 452, "score" : 10.168, "alignment" : "-------------------SANGVFCHVDSLVVSYLGYLPQDMMNHS-IFNFYCSEDLPMLRDVYKEVMSEQ", "location-fragments" : [ { "start" : 401, "end" : 452, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50112" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 86, "end" : 122, "location-fragments" : [ { "start" : 86, "end" : 122, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 692, "end" : 739, "location-fragments" : [ { "start" : 692, "end" : 739, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF12114", "name" : "Period_C", "description" : "Period protein 2/3C-terminal region", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022728", "name" : "Period_circadian-like_C", "description" : "Period circadian-like, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 956, "end" : 1099, "hmmStart" : 48, "hmmEnd" : 185, "hmmLength" : 195, "hmmBounds" : "INCOMPLETE", "evalue" : 2.6E-14, "score" : 53.2, "envelopeStart" : 908, "envelopeEnd" : 1110, "postProcessed" : true, "location-fragments" : [ { "start" : 956, "end" : 1099, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-14, "score" : 53.2, "model-ac" : "PF12114" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 571, "end" : 674, "location-fragments" : [ { "start" : 571, "end" : 674, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00091", "name" : "pas_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 384, "end" : 450, "hmmStart" : 1, "hmmEnd" : 68, "hmmLength" : 68, "hmmBounds" : "COMPLETE", "evalue" : 0.18, "score" : 20.9, "location-fragments" : [ { "start" : 384, "end" : 450, "dc-status" : "CONTINUOUS" } ] }, { "start" : 224, "end" : 294, "hmmStart" : 1, "hmmEnd" : 68, "hmmLength" : 68, "hmmBounds" : "COMPLETE", "evalue" : 0.0034, "score" : 26.6, "location-fragments" : [ { "start" : 224, "end" : 294, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-9, "score" : 47.5, "model-ac" : "SM00091" }, { "signature" : { "accession" : "PS50112", "name" : "PAS", "description" : "PAS repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 247, "end" : 282, "score" : 10.908, "alignment" : "---------------------DGIVLYTSSGLTDVLGFHKDMWLGRS-FTDFVHPKDR--------------", "location-fragments" : [ { "start" : 247, "end" : 282, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50112" }, { "signature" : { "accession" : "PTHR11269", "name" : "PERIOD CIRCADIAN PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 1123, "hmmStart" : 8, "hmmEnd" : 1196, "hmmLength" : 1203, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 1127, "location-fragments" : [ { "start" : 5, "end" : 1123, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-208, "familyName" : "PERIOD CIRCADIAN PROTEIN", "score" : 699.0, "model-ac" : "PTHR11269" }, { "signature" : { "accession" : "SSF55785", "name" : "PYP-like sensor domain (PAS domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035965", "name" : "PAS-like_dom_sf", "description" : "PAS domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 238, "end" : 289, "hmmLength" : 109, "location-fragments" : [ { "start" : 238, "end" : 289, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.02E-8, "model-ac" : "0048579" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 600, "end" : 662, "location-fragments" : [ { "start" : 600, "end" : 662, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:1.20.5.770", "name" : "Single helix bin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 542, "end" : 575, "hmmStart" : 4, "hmmEnd" : 32, "hmmLength" : 34, "hmmBounds" : "COMPLETE", "evalue" : 6.1E-10, "score" : 40.5, "envelopeStart" : 542, "envelopeEnd" : 575, "postProcessed" : true, "location-fragments" : [ { "start" : 542, "end" : 575, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-10, "score" : 41.6, "model-ac" : "1wa9B03" }, { "signature" : { "accession" : "PF14598", "name" : "PAS_11", "description" : "PAS domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 395, "end" : 499, "hmmStart" : 3, "hmmEnd" : 109, "hmmLength" : 113, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-11, "score" : 44.1, "envelopeStart" : 393, "envelopeEnd" : 502, "postProcessed" : true, "location-fragments" : [ { "start" : 395, "end" : 499, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-14, "score" : 54.5, "model-ac" : "PF14598" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 692, "end" : 706, "location-fragments" : [ { "start" : 692, "end" : 706, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00130", "name" : "PAS", "description" : "PAS", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000014", "name" : "PAS", "description" : "PAS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 241, "end" : 285, "sites" : [ ], "evalue" : 2.59926E-5, "score" : 42.2351, "location-fragments" : [ { "start" : 241, "end" : 285, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00130" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 122, "location-fragments" : [ { "start" : 1, "end" : 122, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.450.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 235, "end" : 380, "hmmStart" : 4, "hmmEnd" : 138, "hmmLength" : 138, "hmmBounds" : "COMPLETE", "evalue" : 9.7E-36, "score" : 124.9, "envelopeStart" : 235, "envelopeEnd" : 380, "postProcessed" : true, "location-fragments" : [ { "start" : 235, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-41, "score" : 141.3, "model-ac" : "3rtyB01" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 63, "location-fragments" : [ { "start" : 1, "end" : 63, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.450.20", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 381, "end" : 539, "hmmStart" : 2, "hmmEnd" : 157, "hmmLength" : 158, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-42, "score" : 146.2, "envelopeStart" : 381, "envelopeEnd" : 539, "postProcessed" : true, "location-fragments" : [ { "start" : 381, "end" : 539, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-52, "score" : 179.4, "model-ac" : "4dj2B02" }, { "signature" : { "accession" : "PTHR11269:SF16", "name" : "PERIOD CIRCADIAN PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 1123, "hmmStart" : 8, "hmmEnd" : 1196, "hmmLength" : 1203, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 1127, "location-fragments" : [ { "start" : 5, "end" : 1123, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-208, "familyName" : "PERIOD CIRCADIAN PROTEIN", "score" : 699.0, "model-ac" : "PTHR11269:SF16" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 940, "end" : 960, "location-fragments" : [ { "start" : 940, "end" : 960, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910244.1 PREDICTED: period circadian protein isoform X3 [Bemisia tabaci]", "id" : "XP_018910244.1" } ] },{ "sequence" : "MKPLLYSTKDAALNQIGWRRCGDNISYFRNDSNGEDEQNANYILSFNLEFPHDNDVVYLAHCYPYTYSDLQDYLIKLQNHPIKSTYSKLRLLCRSLAGNNVYYLTVTSPCLPDEPKKRKAVVITGRVHPGETPSSWMMKGFMDYLTGDSEQAKELRDKFIFKLVPMLNPDGVIVGNNRCSLTGRDLNRQYRTVIRETYPSIWHTKLMIRRLMEECGIVMYCDLHAHSRKHNVFIYGCENKRYPEKRLYEQVFPLMLHKNAADKFSFENCKFRIQKSKEGTGRVVIWMMGVCNSYTMEASFGGSTIGSRVDTHFSAQDYENIGRAFCETLLDFCDEDPCKERLRSKIVSRLVKEGSSADEPTNINLSDYSSDEGDTSSCTDDETTDKPTLPASAPPSSPLCPRQKGTQKLKETSPKTNMSQPLSSYSSPLPRKILQVHCANLDIFSRESDVDSGGESPVGGHISRSMERNNIGRIFGENFQLLNRGHMPPELMITTAQVYDMQIVTEGNTSFTKETKDTKDFYSEVCQTDSDYSWSPERSKSQVTSKITILRSDFSPEIRVGFHRSVSLQQRLWSRSDLEAGLLAWSSPILCTDTAILRSCSHKLSLLKEHRGKGKAKSTNREKKQEKAALSRNKYKQAIMRVEDAELIGEKAEYAEHLDVKYTKLKKKKIKKKGLGKQSLEIPQKALRKGDSASSSSNSGGVSKAEIMKIQNQMPEDDKATRSRKKKKQRFVNIHRKIRKVINAVTTSNGDRSVCSNEDYKPI", "md5" : "abd9eb14f2287cd2a26d4154f9098089", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 358, "end" : 426, "location-fragments" : [ { "start" : 358, "end" : 426, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.40.630.10", "name" : "Zn peptidases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 74, "end" : 336, "hmmStart" : 14, "hmmEnd" : 258, "hmmLength" : 262, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-80, "score" : 270.9, "envelopeStart" : 74, "envelopeEnd" : 336, "postProcessed" : true, "location-fragments" : [ { "start" : 74, "end" : 336, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-80, "score" : 272.0, "model-ac" : "4a37A02" }, { "signature" : { "accession" : "cd06907", "name" : "M14_AGBL2-3_like", "description" : "M14_AGBL2-3_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 83, "end" : 333, "sites" : [ { "description" : "Zn binding site", "numLocations" : 3, "siteLocations" : [ { "start" : 128, "end" : 128, "residue" : "H" }, { "start" : 224, "end" : 224, "residue" : "H" }, { "start" : 131, "end" : 131, "residue" : "E" } ] }, { "description" : "active site", "numLocations" : 9, "siteLocations" : [ { "start" : 297, "end" : 297, "residue" : "E" }, { "start" : 187, "end" : 187, "residue" : "N" }, { "start" : 225, "end" : 225, "residue" : "A" }, { "start" : 234, "end" : 234, "residue" : "I" }, { "start" : 128, "end" : 128, "residue" : "H" }, { "start" : 224, "end" : 224, "residue" : "H" }, { "start" : 188, "end" : 188, "residue" : "R" }, { "start" : 131, "end" : 131, "residue" : "E" }, { "start" : 178, "end" : 178, "residue" : "R" } ] } ], "evalue" : 1.44894E-171, "score" : 491.041, "location-fragments" : [ { "start" : 83, "end" : 333, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd06907" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 689, "end" : 706, "location-fragments" : [ { "start" : 689, "end" : 706, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 399, "end" : 426, "location-fragments" : [ { "start" : 399, "end" : 426, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 681, "end" : 731, "location-fragments" : [ { "start" : 681, "end" : 731, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 611, "end" : 630, "location-fragments" : [ { "start" : 611, "end" : 630, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 358, "end" : 373, "location-fragments" : [ { "start" : 358, "end" : 373, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12756:SF23", "name" : "CYTOSOLIC CARBOXYPEPTIDASE 3", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 355, "hmmStart" : 239, "hmmEnd" : 597, "hmmLength" : 877, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 420, "location-fragments" : [ { "start" : 1, "end" : 355, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-175, "familyName" : "CYTOSOLIC CARBOXYPEPTIDASE 3", "score" : 589.2, "model-ac" : "PTHR12756:SF23" }, { "signature" : { "accession" : "PTHR12756", "name" : "ATP/GTP-BINDING MOTIF CONTAINING PROTEIN RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 355, "hmmStart" : 239, "hmmEnd" : 597, "hmmLength" : 877, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 420, "location-fragments" : [ { "start" : 1, "end" : 355, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-175, "familyName" : "CYTOSOLIC CARBOXYPEPTIDASE 3", "score" : 589.2, "model-ac" : "PTHR12756" }, { "signature" : { "accession" : "SSF53187", "name" : "Zn-dependent exopeptidases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 55, "end" : 335, "hmmLength" : 323, "location-fragments" : [ { "start" : 55, "end" : 335, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.95E-59, "model-ac" : "0048537" }, { "signature" : { "accession" : "PF00246", "name" : "Peptidase_M14", "description" : "Zinc carboxypeptidase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000834", "name" : "Peptidase_M14", "description" : "Peptidase M14, carboxypeptidase A", "type" : "DOMAIN", "goXRefs" : [ { "name" : "proteolysis", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006508" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" }, { "name" : "metallocarboxypeptidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004181" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 86, "end" : 302, "hmmStart" : 15, "hmmEnd" : 266, "hmmLength" : 287, "hmmBounds" : "INCOMPLETE", "evalue" : 8.2E-20, "score" : 71.8, "envelopeStart" : 70, "envelopeEnd" : 318, "postProcessed" : true, "location-fragments" : [ { "start" : 86, "end" : 302, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-20, "score" : 73.0, "model-ac" : "PF00246" } ], "xref" : [ { "name" : "XP_018910136.1 PREDICTED: cytosolic carboxypeptidase 2-like [Bemisia tabaci]", "id" : "XP_018910136.1" } ] },{ "sequence" : "MKEMVGGCCVCSDERGWAENPLVYCDGQGCTVAVHQACYGIVSVPQGNWYCRKCESQERSARVRCELCPCKDGALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPILLHQIPPERFNKTCYICEENGKGSKATNGACMQCNKAGCRQQFHVTCAQAMGLLCEEAGNYLDNVKYCGYCQHHYSKLKKGGNVKPIPPYRPVPSTNPLDSSPEKETIDKSVPKRKTSSTTKSGGPVITSTDKPGVLKLSISTKGSSVEINSAAEESSTLSAQPAAIPTSTSSSVKSELSDKFTTLNFVESIVAPSESVFGDSKNKKRKGGARTPPNSAPKDSEVSPSDEKDAKKMLDINATEQGGDANAPSVVVKAEGAYPSPSSAAPLTPGSGFSSPAVSKASSTNSATPTTNSIVVSVPYSTAAPAIASTNAAAHGSDMSPAKRSRSQSNEKSEKGKKKRHSVSGSTSPAGGKKSLAGSRTSSPTPDTNAAPKDSPPSSPEISNKKGNNSTTKGRRGSMSLSQPQPQPQAQPVKDEKETKLFQNGVVNAPHMLGNQLNPSSMMAQKMTDTLNAELEAHSIYRAEPNASLVGPQLYSRVISEARSGRSTPNANLSTSTTVTTAATTTTSTASSNGAVSWSSLGGGNIPQTLDQLLERQWEHGSQFLMEQAQHFDIASLLSCLHQLRAENLRLEEHVNSLVQRRDHLLAVNARLAIPLTPVTQVNNVHPATVQQVNESRTSAIHSVGAQQRINNVYSQPPPMENGLSASPPTMYQHRNPHQQPPQSSPNIRHHNSPAVYATVHPTITTPGVVRTSADPMSRPDARRSVPSNANMAASGSSIQSGGYSTAMYSMPTSQQQMVVRRNEMHHMSSSKPPS", "md5" : "e2d1174af1e0b3c6cf09172f6c23894d", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 670, "end" : 690, "location-fragments" : [ { "start" : 670, "end" : 690, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF13831", "name" : "PHD_2", "description" : "PHD-finger", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 20, "end" : 55, "hmmStart" : 2, "hmmEnd" : 36, "hmmLength" : 36, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.5E-12, "score" : 46.8, "envelopeStart" : 19, "envelopeEnd" : 55, "postProcessed" : true, "location-fragments" : [ { "start" : 20, "end" : 55, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-12, "score" : 46.8, "model-ac" : "PF13831" }, { "signature" : { "accession" : "PS51805", "name" : "EPHD", "description" : "Extended PHD (ePHD) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR034732", "name" : "EPHD", "description" : "Extended PHD (ePHD) domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 62, "end" : 181, "score" : 28.175, "alignment" : "RVRCELCPCK--DGALKKTDNS-GWAHVVCALYIPEVRFGNVTT-MEPILLHQIPPERFNKTCYICEENgkgskatnGACMQCNKAGCRQQFHVTCAQAMGLLCEeAGNYLDNVKycGYCQHHY", "location-fragments" : [ { "start" : 62, "end" : 181, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51805" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 741, "end" : 781, "location-fragments" : [ { "start" : 741, "end" : 781, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd15574", "name" : "PHD_AF10_AF17", "description" : "PHD_AF10_AF17", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 54, "sites" : [ { "description" : "Zn binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 30, "end" : 30, "residue" : "C" }, { "start" : 38, "end" : 38, "residue" : "C" }, { "start" : 54, "end" : 54, "residue" : "C" }, { "start" : 11, "end" : 11, "residue" : "C" }, { "start" : 51, "end" : 51, "residue" : "C" }, { "start" : 25, "end" : 25, "residue" : "C" }, { "start" : 8, "end" : 8, "residue" : "C" }, { "start" : 35, "end" : 35, "residue" : "H" } ] }, { "description" : "putative histone H3 binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 49, "end" : 49, "residue" : "W" }, { "start" : 21, "end" : 21, "residue" : "P" }, { "start" : 7, "end" : 7, "residue" : "G" }, { "start" : 23, "end" : 23, "residue" : "V" }, { "start" : 25, "end" : 25, "residue" : "C" }, { "start" : 22, "end" : 22, "residue" : "L" }, { "start" : 24, "end" : 24, "residue" : "Y" }, { "start" : 31, "end" : 31, "residue" : "T" } ] } ], "evalue" : 7.58595E-33, "score" : 118.384, "location-fragments" : [ { "start" : 7, "end" : 54, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd15574" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 595, "end" : 615, "location-fragments" : [ { "start" : 595, "end" : 615, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 797, "end" : 828, "location-fragments" : [ { "start" : 797, "end" : 828, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 306, "end" : 531, "location-fragments" : [ { "start" : 306, "end" : 531, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.40.10", "name" : "Zinc/RING finger domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013083", "name" : "Znf_RING/FYVE/PHD", "description" : "Zinc finger, RING/FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 61, "hmmStart" : 19, "hmmEnd" : 67, "hmmLength" : 71, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-17, "score" : 64.2, "envelopeStart" : 2, "envelopeEnd" : 61, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 61, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-17, "score" : 64.2, "model-ac" : "2ku3A00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 330, "end" : 344, "location-fragments" : [ { "start" : 330, "end" : 344, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 452, "end" : 521, "location-fragments" : [ { "start" : 452, "end" : 521, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.40.10", "name" : "Zinc/RING finger domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013083", "name" : "Znf_RING/FYVE/PHD", "description" : "Zinc finger, RING/FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 104, "end" : 184, "hmmStart" : 9, "hmmEnd" : 83, "hmmLength" : 87, "hmmBounds" : "COMPLETE", "evalue" : 9.5E-19, "score" : 69.4, "envelopeStart" : 104, "envelopeEnd" : 184, "postProcessed" : true, "location-fragments" : [ { "start" : 104, "end" : 184, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.5E-19, "score" : 69.4, "model-ac" : "2lq6A00" }, { "signature" : { "accession" : "SM00249", "name" : "PHD_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001965", "name" : "Znf_PHD", "description" : "Zinc finger, PHD-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 119, "end" : 178, "hmmStart" : 1, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "COMPLETE", "evalue" : 0.015, "score" : 24.5, "location-fragments" : [ { "start" : 119, "end" : 178, "dc-status" : "CONTINUOUS" } ] }, { "start" : 7, "end" : 55, "hmmStart" : 1, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-6, "score" : 37.8, "location-fragments" : [ { "start" : 7, "end" : 55, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-14, "score" : 62.3, "model-ac" : "SM00249" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 813, "end" : 828, "location-fragments" : [ { "start" : 813, "end" : 828, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR13793:SF106", "name" : "ALHAMBRA, ISOFORM P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 494, "end" : 841, "hmmStart" : 563, "hmmEnd" : 893, "hmmLength" : 957, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 468, "envelopeEnd" : 863, "location-fragments" : [ { "start" : 494, "end" : 841, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1, "end" : 513, "hmmStart" : 2, "hmmEnd" : 492, "hmmLength" : 957, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 528, "location-fragments" : [ { "start" : 1, "end" : 513, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-199, "familyName" : "ALHAMBRA, ISOFORM P", "score" : 666.2, "model-ac" : "PTHR13793:SF106" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 741, "end" : 784, "location-fragments" : [ { "start" : 741, "end" : 784, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57903", "name" : "FYVE/PHD zinc finger", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011011", "name" : "Znf_FYVE_PHD", "description" : "Zinc finger, FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 70, "hmmLength" : 88, "location-fragments" : [ { "start" : 7, "end" : 70, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.31E-11, "model-ac" : "0050474" }, { "signature" : { "accession" : "PS50016", "name" : "ZF_PHD_2", "description" : "Zinc finger PHD-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR019787", "name" : "Znf_PHD-finger", "description" : "Zinc finger, PHD-finger", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5, "end" : 57, "score" : 9.712, "alignment" : "VGGCCVCSDERGWaENPLVYCDgqGCTVAVHQACYGIVSV----PQGNWYCRKCESQ", "location-fragments" : [ { "start" : 5, "end" : 57, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50016" }, { "signature" : { "accession" : "PTHR13793", "name" : "PHD FINGER PROTEINS", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 494, "end" : 841, "hmmStart" : 563, "hmmEnd" : 893, "hmmLength" : 957, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 468, "envelopeEnd" : 863, "location-fragments" : [ { "start" : 494, "end" : 841, "dc-status" : "CONTINUOUS" } ] }, { "start" : 1, "end" : 513, "hmmStart" : 2, "hmmEnd" : 492, "hmmLength" : 957, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 528, "location-fragments" : [ { "start" : 1, "end" : 513, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-199, "familyName" : "ALHAMBRA, ISOFORM P", "score" : 666.2, "model-ac" : "PTHR13793" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 373, "end" : 433, "location-fragments" : [ { "start" : 373, "end" : 433, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd15672", "name" : "ePHD_AF10_like", "description" : "ePHD_AF10_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 65, "end" : 180, "sites" : [ { "description" : "putative histone H3 binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 139, "end" : 139, "residue" : "Q" }, { "start" : 136, "end" : 136, "residue" : "A" }, { "start" : 138, "end" : 138, "residue" : "M" }, { "start" : 140, "end" : 140, "residue" : "C" }, { "start" : 137, "end" : 137, "residue" : "C" }, { "start" : 175, "end" : 175, "residue" : "G" }, { "start" : 119, "end" : 119, "residue" : "T" }, { "start" : 146, "end" : 146, "residue" : "R" } ] }, { "description" : "Zn binding site", "numLocations" : 12, "siteLocations" : [ { "start" : 180, "end" : 180, "residue" : "H" }, { "start" : 123, "end" : 123, "residue" : "C" }, { "start" : 68, "end" : 68, "residue" : "C" }, { "start" : 140, "end" : 140, "residue" : "C" }, { "start" : 65, "end" : 65, "residue" : "C" }, { "start" : 145, "end" : 145, "residue" : "C" }, { "start" : 153, "end" : 153, "residue" : "C" }, { "start" : 177, "end" : 177, "residue" : "C" }, { "start" : 85, "end" : 85, "residue" : "H" }, { "start" : 150, "end" : 150, "residue" : "H" }, { "start" : 88, "end" : 88, "residue" : "C" }, { "start" : 120, "end" : 120, "residue" : "C" } ] } ], "evalue" : 4.47197E-78, "score" : 246.219, "location-fragments" : [ { "start" : 65, "end" : 180, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd15672" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 434, "end" : 450, "location-fragments" : [ { "start" : 434, "end" : 450, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 192, "end" : 237, "location-fragments" : [ { "start" : 192, "end" : 237, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS01359", "name" : "ZF_PHD_1", "description" : "Zinc finger PHD-type signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019786", "name" : "Zinc_finger_PHD-type_CS", "description" : "Zinc finger, PHD-type, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 54, "level" : "STRONG", "cigarAlignment" : "1M2I1M11I1M1I1M4I1M3I2M2I1M10I1M1I1M2I1M", "alignment" : "CcvCsdergwaenplVyCdgqgCtvaVHqaCygivsvpqgnWyCrkC", "location-fragments" : [ { "start" : 8, "end" : 54, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS01359" }, { "signature" : { "accession" : "PF13832", "name" : "zf-HC5HC2H_2", "description" : "PHD-zinc-finger like domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 64, "end" : 180, "hmmStart" : 2, "hmmEnd" : 110, "hmmLength" : 110, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.3E-30, "score" : 105.8, "envelopeStart" : 63, "envelopeEnd" : 180, "postProcessed" : true, "location-fragments" : [ { "start" : 64, "end" : 180, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.8E-31, "score" : 106.2, "model-ac" : "PF13832" } ], "xref" : [ { "name" : "XP_018909859.1 PREDICTED: protein AF-10-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909859.1" } ] },{ "sequence" : "MRDGSDPVGRGSGGIDRGGGMEGCYIPNNPAHYGLDGGWSIGVTDELSLPTLDLDPLPSLFPFSPCSGTTAPTASYKSEFSTLIGKNGDEVGVREPHDMADVLLSLKHAIVHPGHTCSSSPFTHSYSSSPYSLHPQQMMPVSPGAGSYSDGGGCNNGVPGFNLDPADLCMTSNAGGNWSANTNTNQSPIFPSMSVNVSMNMTMHGYPSVMSEHQITYPQVCVLR", "md5" : "e7992b4341460e093aa1e63a6ae4d5d3", "matches" : [ ], "xref" : [ { "name" : "XP_018910032.1 PREDICTED: protein glass-like [Bemisia tabaci]", "id" : "XP_018910032.1" } ] },{ "sequence" : "MKMKSPQHLCVLYVATAGLQGNALGSDEQEVVLLVYVIVEVSANKVIGVQQYVVKPTVADINENVLSEQLVSESSLTEELVKSSGVPLQTAIQKFDSYVRSIKVEPNSPAFRFVTDGQLPLRQCLHPEACNKEIELPDCYNTFHDLRKDFRKFYSVPETEELSSISDLINYLGMNSVTDSEFYVKEAKDMVNLVQRLIADGHCFSNPEIVEIKLEPGICSKDEEIDNNCVVKARGLPWQSSDQDIAKFFRGLNMAKGGVALCLSAQGRRNGEALVRFVNQEHRDMALKRHKHHIANRYIEVYKAPGEDFINVAGGRTTEAETFLTQGAEVIIRMRGLPYDCTASQIISFFEAGPEDKACHVMNGEEGVLFVKKPDKKATGDAFVLFAEESDAPKALSKHRQLIGVRYIELFRSTPAEVQQVLNRSLDTKSFESKLVMPQIQPPVPLVPQFVITSGVRKDCIRLRGLPYEASVENILEFLGDFSKNIVYQGVHMVYNSQGQPSGEAFIQMDSEASAFQAAQGRHHRYMIYGKKQRYIEVFQCSSDDMNLVHSGGLQSTNASSPVTKALISPGGTMIGPSFSPGGVIPYSAYSHTHTQPMLGPMNTSRCQSVQPPTIAPPNFFQPIVYWPYPSSPVSPPHQPPTLVIMQSPPPPPPPPYSMHHDVANFLHSMSDWGMDYMAPNSQLNGPPMNFGPMGIHPAVA", "md5" : "f3e555f06cdb232da25b66cf3d715f93", "matches" : [ { "signature" : { "accession" : "SM00360", "name" : "rrm1_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 331, "end" : 411, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 0.0032, "score" : 26.7, "location-fragments" : [ { "start" : 331, "end" : 411, "dc-status" : "CONTINUOUS" } ] }, { "start" : 460, "end" : 539, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 0.037, "score" : 19.4, "location-fragments" : [ { "start" : 460, "end" : 539, "dc-status" : "CONTINUOUS" } ] }, { "start" : 230, "end" : 302, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 0.043, "score" : 18.7, "location-fragments" : [ { "start" : 230, "end" : 302, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-14, "score" : 64.8, "model-ac" : "SM00360" }, { "signature" : { "accession" : "PTHR13976:SF37", "name" : "EPITHELIAL SPLICING REGULATORY PROTEIN 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 159, "end" : 572, "hmmStart" : 155, "hmmEnd" : 554, "hmmLength" : 681, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 17, "envelopeEnd" : 610, "location-fragments" : [ { "start" : 159, "end" : 572, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.2E-165, "familyName" : "EPITHELIAL SPLICING REGULATORY PROTEIN 1", "score" : 553.3, "model-ac" : "PTHR13976:SF37" }, { "signature" : { "accession" : "PTHR13976", "name" : "HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 159, "end" : 572, "hmmStart" : 155, "hmmEnd" : 554, "hmmLength" : 681, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 17, "envelopeEnd" : 610, "location-fragments" : [ { "start" : 159, "end" : 572, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.2E-165, "familyName" : "EPITHELIAL SPLICING REGULATORY PROTEIN 1", "score" : 553.3, "model-ac" : "PTHR13976" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 453, "end" : 553, "hmmStart" : 6, "hmmEnd" : 94, "hmmLength" : 98, "hmmBounds" : "COMPLETE", "evalue" : 4.7E-26, "score" : 92.5, "envelopeStart" : 453, "envelopeEnd" : 553, "postProcessed" : true, "location-fragments" : [ { "start" : 453, "end" : 553, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-75, "score" : 250.5, "model-ac" : "2rvjA01" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 312, "end" : 433, "hmmStart" : 8, "hmmEnd" : 114, "hmmLength" : 123, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.5E-29, "score" : 102.6, "envelopeStart" : 310, "envelopeEnd" : 433, "postProcessed" : true, "location-fragments" : [ { "start" : 312, "end" : 433, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.5E-77, "score" : 256.6, "model-ac" : "2dhaA00" }, { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 330, "end" : 415, "score" : 8.621, "alignment" : "VIIRMRGLPYDCTASQIISFF-EAGPEDKACHVMNgeegvlfvkkPDKKATGDAFVLFAEESDAPKALSkhrQLIGV----RYIELFRSTP", "location-fragments" : [ { "start" : 330, "end" : 415, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" }, { "signature" : { "accession" : "SSF54928", "name" : "RNA-binding domain, RBD", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035979", "name" : "RBD_domain_sf", "description" : "RNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 332, "end" : 527, "hmmLength" : 183, "location-fragments" : [ { "start" : 332, "end" : 425, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 456, "end" : 527, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.64E-16, "model-ac" : "0049769" }, { "signature" : { "accession" : "SSF54928", "name" : "RNA-binding domain, RBD", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035979", "name" : "RBD_domain_sf", "description" : "RNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 223, "end" : 314, "hmmLength" : 102, "location-fragments" : [ { "start" : 223, "end" : 314, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.99E-16, "model-ac" : "0050478" }, { "signature" : { "accession" : "cd12743", "name" : "RRM3_Fusilli", "description" : "RRM3_Fusilli", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 458, "end" : 542, "sites" : [ ], "evalue" : 4.03656E-52, "score" : 172.768, "location-fragments" : [ { "start" : 458, "end" : 542, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12743" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 226, "end" : 311, "hmmStart" : 8, "hmmEnd" : 91, "hmmLength" : 100, "hmmBounds" : "INCOMPLETE", "evalue" : 1.1E-20, "score" : 75.3, "envelopeStart" : 221, "envelopeEnd" : 312, "postProcessed" : true, "location-fragments" : [ { "start" : 226, "end" : 311, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-77, "score" : 256.3, "model-ac" : "2hglA01" }, { "signature" : { "accession" : "G3DSA:3.30.420.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036397", "name" : "RNaseH_sf", "description" : "Ribonuclease H superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 225, "hmmStart" : 13, "hmmEnd" : 207, "hmmLength" : 242, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.8E-28, "score" : 100.1, "envelopeStart" : 2, "envelopeEnd" : 229, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 225, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-28, "score" : 100.9, "model-ac" : "4qozB02" } ], "xref" : [ { "name" : "XP_018910049.1 PREDICTED: RNA-binding protein fusilli isoform X2 [Bemisia tabaci]", "id" : "XP_018910049.1" } ] },{ "sequence" : "MSCHLKPFAKLLDLDSIQRSLSFPEITENAGETETQKHGKSDTSSTDSKWLKDCHISVSPTGEMMVIANKHNMIILNSKWDAQEESEVKMKYRVSECIDPRQIENETVTSVLVLPLAIAQNRKSSVAQAEWICIMVGFSTGYVRFFTELGLQLLSHPLHDEPILKLKCQSYQPGRHSMCGEQLEEVYVVYPSCICILPGPLLFNVLRACRNQLARVTANCSDIVPTPPLTFKKWGYKQGQVTDSAVVGLTSANMFQHLYTASVCGGFNSWYQSSAPQSTLVVASGKPFLGFHYVLGSGSQQILSDLAKLVTNKLKSALGNVVSGWLGGGGRRGSASSEKQAPVIEPPEAMSIRFGLNDVNRQSSSVLLSPQRNLAAICDNLGRVILVDCNSGLAIRMWKGYRNAQCGWLEVKEEERKARGHRRTALFLVIYAPKKALIEIWAMQQGPKVASFPVDNYGRLVYNNYELMCGNGTSRNSNQGLINSCLFIDPLGQISEIFAPFHCALNTESSVRAQDIHLVKNLRHSLHSDETSEEKLIEEVKKTAMKLKTFDMKSQCLDLLINDKYTSPSLLSAFLDNLESNTEDEMSSDLNPEHKELYIKVRNLRSLVSFYQFVHALHLKPPEYSTVVESDDKHVEALCETLQITEEEFERLNCLVRSSDMVDEGKSRAKVTFSSNKGEFSEFLNSFNLNAENGVISLVCDFAEEKLFRISELVCQGAAGKCCPIVEWQSACRESQIMSFDLLKILLKYWLKKKHQSKLYYIEMLNFTKLIIAVCQLNGIKSHFWPELRKLIAASTDCISALSISFIFRGVAAMFEKIVVEHLDKNSKESLVAADDEEATKVYNLEDWENVSADGCEWSQMIDDLTEVAALCTTLCKVSIRSFSSECSVAHLPYENPSINLNSLLSEGKGFICELVAKWLGANAIHPDFIIDKNDIEFHLNNVESPKANAKRKRDSSPPKKSLMSPILEGSYVEVDESREAKPVNQHEAYILESLIQLKKHFPYILSSSNILANLAWEYILAWQRSLETMELFSSAVQCLRLTPSLDLKQGLCSLIWTTHLQQRFELAVRLIHKVGKVPKERLCMQDVGFSDEKMTTFLSICSQFIDVFVEAAAVAGISPKSNRHKQKLYKQIMLCRLASEQAEPNFDLLCIIRQCVEAFLILATFNLKTTKPLQALFDSNSQAAMFSDITKQPQLQISRQGMDVKLIESRVKFLKRAVSSAVQLIEKTVNQNNEIDLNTVATIDWISKIMSLVSDWAISPDIIRMHYVCELYHNGYDRLAEEIIPAVRDQDEMGTQLLIIAGQRIKQFIIQSHQFRETTSNLSPAVTSWLASLEENETMQPSNTPDIGQLLRTVISLLPDNHKDKALASLVLEGLPSCDR", "md5" : "5c23b688e85957cd1f5b89f87846749e", "matches" : [ { "signature" : { "accession" : "PF14655", "name" : "RAB3GAP2_N", "description" : "Rab3 GTPase-activating protein regulatory subunit N-terminus", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR032839", "name" : "RAB3GAP_N", "description" : "Rab3-GAP regulatory subunit, N-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "COPI-independent Golgi-to-ER retrograde traffic", "databaseName" : "Reactome", "id" : "R-HSA-6811436" }, { "name" : "RAB GEFs exchange GTP for GDP on RABs", "databaseName" : "Reactome", "id" : "R-HSA-8876198" } ] } }, "locations" : [ { "start" : 50, "end" : 461, "hmmStart" : 1, "hmmEnd" : 417, "hmmLength" : 417, "hmmBounds" : "COMPLETE", "evalue" : 9.6E-130, "score" : 433.5, "envelopeStart" : 50, "envelopeEnd" : 461, "postProcessed" : true, "location-fragments" : [ { "start" : 50, "end" : 461, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-130, "score" : 435.6, "model-ac" : "PF14655" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 25, "end" : 44, "location-fragments" : [ { "start" : 25, "end" : 44, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF14656", "name" : "RAB3GAP2_C", "description" : "Rab3 GTPase-activating protein regulatory subunit C-terminus", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR029257", "name" : "RAB3GAP2_C", "description" : "Rab3GAP regulatory subunit, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "RAB GEFs exchange GTP for GDP on RABs", "databaseName" : "Reactome", "id" : "R-HSA-8876198" }, { "name" : "COPI-independent Golgi-to-ER retrograde traffic", "databaseName" : "Reactome", "id" : "R-HSA-6811436" } ] } }, "locations" : [ { "start" : 741, "end" : 1360, "hmmStart" : 1, "hmmEnd" : 598, "hmmLength" : 598, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-139, "score" : 464.5, "envelopeStart" : 741, "envelopeEnd" : 1360, "postProcessed" : true, "location-fragments" : [ { "start" : 741, "end" : 1360, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-139, "score" : 464.9, "model-ac" : "PF14656" }, { "signature" : { "accession" : "PTHR12472", "name" : "RAB3-GAP REGULATORY DOMAIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR026059", "name" : "Rab3-gap_reg", "description" : "Rab3-GAP regulatory subunit", "type" : "FAMILY", "goXRefs" : [ { "name" : "regulation of GTPase activity", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0043087" } ], "pathwayXRefs" : [ { "name" : "RAB GEFs exchange GTP for GDP on RABs", "databaseName" : "Reactome", "id" : "R-HSA-8876198" }, { "name" : "COPI-independent Golgi-to-ER retrograde traffic", "databaseName" : "Reactome", "id" : "R-HSA-6811436" } ] } }, "locations" : [ { "start" : 1, "end" : 1339, "hmmStart" : 1, "hmmEnd" : 1079, "hmmLength" : 1111, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 1354, "location-fragments" : [ { "start" : 1, "end" : 1339, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-212, "familyName" : "RAB3-GAP REGULATORY DOMAIN", "score" : 710.0, "model-ac" : "PTHR12472" } ], "xref" : [ { "name" : "XP_018910161.1 PREDICTED: rab3 GTPase-activating protein non-catalytic subunit [Bemisia tabaci]", "id" : "XP_018910161.1" } ] },{ "sequence" : "MHRLAEAENQYVTLIMITLQVILISGLIPNLPEDIERKCLRDGIKPDIVDVIPDFEIEVMFGDGVLVEFGNEINERECQEEPNVLWPFEKNTTHYTLIMTDPDYPTRSNASQREFQHWLIGNIPGTVEGNGEELTPWYPPHPIKFGGFHRYTFIVFMQPEGEKIKFDEPKLNDSVHGRAHFNTKKFAAKYNLGDPVAINYFRAESFYG", "md5" : "c6540eafac8a92520072558e6b39f8ce", "matches" : [ { "signature" : { "accession" : "PF01161", "name" : "PBP", "description" : "Phosphatidylethanolamine-binding protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR008914", "name" : "PEBP", "description" : "Phosphatidylethanolamine-binding protein", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 79, "end" : 200, "hmmStart" : 12, "hmmEnd" : 132, "hmmLength" : 132, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.0E-15, "score" : 57.2, "envelopeStart" : 57, "envelopeEnd" : 201, "postProcessed" : true, "location-fragments" : [ { "start" : 79, "end" : 200, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-15, "score" : 57.7, "model-ac" : "PF01161" }, { "signature" : { "accession" : "G3DSA:3.90.280.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 207, "hmmStart" : 13, "hmmEnd" : 175, "hmmLength" : 190, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-53, "score" : 183.6, "envelopeStart" : 32, "envelopeEnd" : 207, "postProcessed" : true, "location-fragments" : [ { "start" : 32, "end" : 207, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-54, "score" : 184.2, "model-ac" : "2iqyA00" }, { "signature" : { "accession" : "cd00866", "name" : "PEBP_euk", "description" : "PEBP_euk", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR035810", "name" : "PEBP_euk", "description" : "Phosphatidylethanolamine-binding protein, eukaryotic", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 57, "end" : 203, "sites" : [ { "description" : "substrate binding site", "numLocations" : 9, "siteLocations" : [ { "start" : 143, "end" : 143, "residue" : "I" }, { "start" : 151, "end" : 151, "residue" : "Y" }, { "start" : 142, "end" : 142, "residue" : "P" }, { "start" : 117, "end" : 117, "residue" : "H" }, { "start" : 141, "end" : 141, "residue" : "H" }, { "start" : 149, "end" : 149, "residue" : "H" }, { "start" : 140, "end" : 140, "residue" : "P" }, { "start" : 115, "end" : 115, "residue" : "F" }, { "start" : 101, "end" : 101, "residue" : "D" } ] } ], "evalue" : 4.79747E-49, "score" : 155.224, "location-fragments" : [ { "start" : 57, "end" : 203, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00866" }, { "signature" : { "accession" : "PTHR11362", "name" : "PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR035810", "name" : "PEBP_euk", "description" : "Phosphatidylethanolamine-binding protein, eukaryotic", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 38, "end" : 204, "hmmStart" : 10, "hmmEnd" : 174, "hmmLength" : 188, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 32, "envelopeEnd" : 207, "location-fragments" : [ { "start" : 38, "end" : 204, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-46, "familyName" : "", "score" : 161.5, "model-ac" : "PTHR11362" }, { "signature" : { "accession" : "PTHR11362:SF7", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 38, "end" : 204, "hmmStart" : 10, "hmmEnd" : 174, "hmmLength" : 188, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 32, "envelopeEnd" : 207, "location-fragments" : [ { "start" : 38, "end" : 204, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-46, "familyName" : "", "score" : 161.5, "model-ac" : "PTHR11362:SF7" }, { "signature" : { "accession" : "SSF49777", "name" : "PEBP-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036610", "name" : "PEBP-like_sf", "description" : "PEBP-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 204, "hmmLength" : 185, "location-fragments" : [ { "start" : 42, "end" : 204, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.46E-44, "model-ac" : "0034862" } ], "xref" : [ { "name" : "XP_018909719.1 PREDICTED: protein D3-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909719.1" } ] },{ "sequence" : "MLIPKYFPAYLFLHLLAAEHVNAWDWSLTGIYEPPFPIKPIPLFANYCQVYTMEINKTVSYLFEYPNYKDVSDLEPPRVTISSTSADESYPIIIVVQQRRSVLSWKLPLTIQSKQNSYAYHRTSRTLCTDLEDVQNPEGEHEMVISVSTSSPSNVNFSLEVVKQQNFSIKLEDEYETVITPSEPAFFLYNFSENVSSVLLEIDSPDKTCMTLSIQNISCPVFDLEHTIQYRGDWETVSSKGGIMLTRQDFPEGLYIVFDLHSDDSDCISSTVDGPEVDVSEADRKKVIRFKLNKNLNYEDYLFASLAVLLSFSSVFILSGLLLCCTRKSPETVTVSEESCTVISAGEIINPNDSVSADSSLDEEETDKSSKESKELVGTKTFLFVSDLSKKNPQAVQAKARLYFWNLLTVAVFYSLPVVQLVFTYQKVLNMSGNQDMCYYNFLCSHRLLQISDFNHVFTNIGYILLGLLFILLVYRKDAACQLHSTKGIPHHFGLYYSMGTALMMEGILSACYHICPNHSNIQFDTSFMYIIAMLSMLKIYQNRHSDINASAYTTYLVLACVIFIGMCGILNGSFIFYVVFTALHIITCFFLSLQIYYMGRWKLGFHSFKRTIIEFFTNLRAGLRHCKPMYPNRMVLLILGNACNWGLAVHLWMSNRSNFATYLLIIFMANLILYLTFYITMKLLSGERILLQPSLYIIFAVIFWGASGYFFTSRSTNWQLTPAESRTYNKSCMLLKFYDNHDIWHLISAGSMFFSFMVLLTLDDDLKDKERKLIPVF", "md5" : "56bde2cf3ba2542953313b65d2b0ede4", "matches" : [ { "signature" : { "accession" : "PTHR12185", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR025958", "name" : "SID1_TM_fam", "description" : "SID1 transmembrane family", "type" : "FAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 45, "end" : 778, "hmmStart" : 19, "hmmEnd" : 716, "hmmLength" : 716, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 40, "envelopeEnd" : 778, "location-fragments" : [ { "start" : 45, "end" : 778, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.6E-222, "familyName" : "FAMILY NOT NAMED", "score" : 740.7, "model-ac" : "PTHR12185" }, { "signature" : { "accession" : "PF13965", "name" : "SID-1_RNA_chan", "description" : "dsRNA-gated channel SID-1", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR025958", "name" : "SID1_TM_fam", "description" : "SID1 transmembrane family", "type" : "FAMILY", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 182, "end" : 778, "hmmStart" : 1, "hmmEnd" : 603, "hmmLength" : 603, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-221, "score" : 735.5, "envelopeStart" : 182, "envelopeEnd" : 778, "postProcessed" : true, "location-fragments" : [ { "start" : 182, "end" : 778, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-221, "score" : 735.8, "model-ac" : "PF13965" } ], "xref" : [ { "name" : "XP_018910555.1 PREDICTED: SID1 transmembrane family member 1-like [Bemisia tabaci]", "id" : "XP_018910555.1" } ] },{ "sequence" : "MSTILETNNKCNLSAVLYQKNDLRMEQKPILEPKENEVLIQMHCVGICGSDVHYLTHGRIADFIVKDPMIIGHEASGIVYKVGEKVKTLKPGDRVAIEPGVPCRTCSFCKEGRYNLCSQIYFCATPPDHGNLSRFYVHAADFCHKLPDHVSMEEGALLEPLSVGVHACKRAGITIGSNVLITGAGPIGLVSLITAKAMGARRVIITDIQEHRLTVAKQCGADYTVLIHKGDDEQELARRIHEELGEAPDKTIDCSGIETTIALGIEATKSGGVIVIVGCGPNNVRIPLIKALSREVDIRGVFRYANDYPAALAMVASGKVNIRQLITHNYVLEDTLSAFETAKTGAGGAIKVMIHCKEGITLENAILNQG", "md5" : "39232d545cc39ef7a963d35b72cb6367", "matches" : [ { "signature" : { "accession" : "PTHR43161:SF9", "name" : "SORBITOL DEHYDROGENASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 359, "hmmStart" : 5, "hmmEnd" : 352, "hmmLength" : 355, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 362, "location-fragments" : [ { "start" : 11, "end" : 359, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-162, "familyName" : "SORBITOL DEHYDROGENASE", "score" : 540.6, "model-ac" : "PTHR43161:SF9" }, { "signature" : { "accession" : "cd05285", "name" : "sorbitol_DH", "description" : "sorbitol_DH", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 356, "sites" : [ { "description" : "inhibitor binding site", "numLocations" : 12, "siteLocations" : [ { "start" : 73, "end" : 73, "residue" : "H" }, { "start" : 302, "end" : 302, "residue" : "F" }, { "start" : 60, "end" : 60, "residue" : "I" }, { "start" : 63, "end" : 63, "residue" : "F" }, { "start" : 159, "end" : 159, "residue" : "E" }, { "start" : 50, "end" : 50, "residue" : "S" }, { "start" : 122, "end" : 122, "residue" : "F" }, { "start" : 279, "end" : 279, "residue" : "C" }, { "start" : 303, "end" : 303, "residue" : "R" }, { "start" : 54, "end" : 54, "residue" : "Y" }, { "start" : 48, "end" : 48, "residue" : "C" }, { "start" : 125, "end" : 125, "residue" : "T" } ] }, { "description" : "tetramer interface", "numLocations" : 15, "siteLocations" : [ { "start" : 199, "end" : 199, "residue" : "G" }, { "start" : 310, "end" : 310, "residue" : "A" }, { "start" : 176, "end" : 176, "residue" : "G" }, { "start" : 165, "end" : 165, "residue" : "V" }, { "start" : 198, "end" : 198, "residue" : "M" }, { "start" : 317, "end" : 317, "residue" : "S" }, { "start" : 197, "end" : 197, "residue" : "A" }, { "start" : 226, "end" : 226, "residue" : "L" }, { "start" : 314, "end" : 314, "residue" : "M" }, { "start" : 178, "end" : 178, "residue" : "N" }, { "start" : 313, "end" : 313, "residue" : "A" }, { "start" : 201, "end" : 201, "residue" : "R" }, { "start" : 194, "end" : 194, "residue" : "T" }, { "start" : 210, "end" : 210, "residue" : "E" }, { "start" : 242, "end" : 242, "residue" : "E" } ] }, { "description" : "catalytic Zn binding site", "numLocations" : 5, "siteLocations" : [ { "start" : 73, "end" : 73, "residue" : "H" }, { "start" : 159, "end" : 159, "residue" : "E" }, { "start" : 50, "end" : 50, "residue" : "S" }, { "start" : 74, "end" : 74, "residue" : "E" }, { "start" : 48, "end" : 48, "residue" : "C" } ] }, { "description" : "NADP binding site", "numLocations" : 18, "siteLocations" : [ { "start" : 302, "end" : 302, "residue" : "F" }, { "start" : 187, "end" : 187, "residue" : "I" }, { "start" : 212, "end" : 212, "residue" : "R" }, { "start" : 208, "end" : 208, "residue" : "I" }, { "start" : 277, "end" : 277, "residue" : "V" }, { "start" : 303, "end" : 303, "residue" : "R" }, { "start" : 257, "end" : 257, "residue" : "I" }, { "start" : 278, "end" : 278, "residue" : "G" }, { "start" : 186, "end" : 186, "residue" : "P" }, { "start" : 254, "end" : 254, "residue" : "C" }, { "start" : 185, "end" : 185, "residue" : "G" }, { "start" : 206, "end" : 206, "residue" : "T" }, { "start" : 255, "end" : 255, "residue" : "S" }, { "start" : 227, "end" : 227, "residue" : "I" }, { "start" : 207, "end" : 207, "residue" : "D" }, { "start" : 279, "end" : 279, "residue" : "C" }, { "start" : 301, "end" : 301, "residue" : "V" }, { "start" : 163, "end" : 163, "residue" : "V" } ] }, { "description" : "structural Zn binding site", "numLocations" : 4, "siteLocations" : [ { "start" : 106, "end" : 106, "residue" : "C" }, { "start" : 103, "end" : 103, "residue" : "C" }, { "start" : 109, "end" : 109, "residue" : "C" }, { "start" : 117, "end" : 117, "residue" : "C" } ] } ], "evalue" : 0.0, "score" : 569.434, "location-fragments" : [ { "start" : 14, "end" : 356, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd05285" }, { "signature" : { "accession" : "G3DSA:3.90.180.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 20, "end" : 342, "hmmStart" : 2, "hmmEnd" : 323, "hmmLength" : 217, "hmmBounds" : "INCOMPLETE", "evalue" : 3.8E-125, "score" : 418.8, "envelopeStart" : 19, "envelopeEnd" : 343, "postProcessed" : true, "location-fragments" : [ { "start" : 303, "end" : 342, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 20, "end" : 162, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 3.3E-125, "score" : 419.0, "model-ac" : "1pl8A01" }, { "signature" : { "accession" : "PTHR43161", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 359, "hmmStart" : 5, "hmmEnd" : 352, "hmmLength" : 355, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 362, "location-fragments" : [ { "start" : 11, "end" : 359, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-162, "familyName" : "SORBITOL DEHYDROGENASE", "score" : 540.6, "model-ac" : "PTHR43161" }, { "signature" : { "accession" : "PS00059", "name" : "ADH_ZINC", "description" : "Zinc-containing alcohol dehydrogenases signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR002328", "name" : "ADH_Zn_CS", "description" : "Alcohol dehydrogenase, zinc-type, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" }, { "name" : "zinc ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008270" } ], "pathwayXRefs" : [ { "name" : "Ethanol oxidation", "databaseName" : "Reactome", "id" : "R-HSA-71384" } ] } }, "locations" : [ { "start" : 72, "end" : 86, "level" : "STRONG", "cigarAlignment" : "3M1I3M4I1M2I1M", "alignment" : "GHEaSGIvykvGekV", "location-fragments" : [ { "start" : 72, "end" : 86, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00059" }, { "signature" : { "accession" : "G3DSA:3.40.50.720", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 163, "end" : 302, "hmmStart" : 2, "hmmEnd" : 323, "hmmLength" : 139, "hmmBounds" : "INCOMPLETE", "evalue" : 3.8E-125, "score" : 418.8, "envelopeStart" : 19, "envelopeEnd" : 343, "postProcessed" : true, "location-fragments" : [ { "start" : 163, "end" : 302, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-125, "score" : 419.0, "model-ac" : "1pl8A02" }, { "signature" : { "accession" : "PF00107", "name" : "ADH_zinc_N", "description" : "Zinc-binding dehydrogenase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013149", "name" : "ADH_C", "description" : "Alcohol dehydrogenase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 186, "end" : 316, "hmmStart" : 1, "hmmEnd" : 129, "hmmLength" : 130, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.5E-23, "score" : 83.2, "envelopeStart" : 186, "envelopeEnd" : 317, "postProcessed" : true, "location-fragments" : [ { "start" : 186, "end" : 316, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.6E-24, "score" : 84.0, "model-ac" : "PF00107" }, { "signature" : { "accession" : "PF08240", "name" : "ADH_N", "description" : "Alcohol dehydrogenase GroES-like domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013154", "name" : "ADH_N", "description" : "Alcohol dehydrogenase, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 36, "end" : 145, "hmmStart" : 2, "hmmEnd" : 108, "hmmLength" : 109, "hmmBounds" : "INCOMPLETE", "evalue" : 2.7E-29, "score" : 101.2, "envelopeStart" : 35, "envelopeEnd" : 146, "postProcessed" : true, "location-fragments" : [ { "start" : 36, "end" : 145, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-29, "score" : 102.6, "model-ac" : "PF08240" }, { "signature" : { "accession" : "SM00829", "name" : "PKS_ER_names_mod", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR020843", "name" : "PKS_ER", "description" : "Polyketide synthase, enoylreductase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 20, "end" : 354, "hmmStart" : 1, "hmmEnd" : 348, "hmmLength" : 348, "hmmBounds" : "COMPLETE", "evalue" : 0.0045, "score" : -137.7, "location-fragments" : [ { "start" : 20, "end" : 354, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0045, "score" : -137.7, "model-ac" : "SM00829" }, { "signature" : { "accession" : "SSF50129", "name" : "GroES-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011032", "name" : "GroES-like_sf", "description" : "GroES-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 184, "hmmLength" : 179, "location-fragments" : [ { "start" : 14, "end" : 184, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.15E-57, "model-ac" : "0046449" }, { "signature" : { "accession" : "SSF51735", "name" : "NAD(P)-binding Rossmann-fold domains", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036291", "name" : "NAD(P)-bd_dom_sf", "description" : "NAD(P)-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 149, "end" : 320, "hmmLength" : 176, "location-fragments" : [ { "start" : 149, "end" : 320, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.39E-37, "model-ac" : "0046253" } ], "xref" : [ { "name" : "XP_018909656.1 PREDICTED: sorbitol dehydrogenase-like [Bemisia tabaci]", "id" : "XP_018909656.1" } ] },{ "sequence" : "MKIEKKLAMCKLYFYGGFLFLPLLWLINVVSFFKISHRKSTVPAEQELYRFVVMSGVGVAVWTVILSVWIYTYQTNRVKWGDFGDDISFLIPTGS", "md5" : "be3351fbdc1fd538b13b58c7e69736b5", "matches" : [ { "signature" : { "accession" : "PF10251", "name" : "PEN-2", "description" : "Presenilin enhancer-2 subunit of gamma secretase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR019379", "name" : "Gamma_Secretase_Asp_P_PEN2", "description" : "Gamma-secretase aspartyl protease complex, presenilin enhancer-2 subunit", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Activated NOTCH1 Transmits Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-2122948" }, { "name" : "Noncanonical activation of NOTCH3", "databaseName" : "Reactome", "id" : "R-HSA-9017802" }, { "name" : "NOTCH3 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-9013507" }, { "name" : "Amyloid fiber formation", "databaseName" : "Reactome", "id" : "R-HSA-977225" }, { "name" : "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2894862" }, { "name" : "NOTCH4 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-9013700" }, { "name" : "NRIF signals cell death from the nucleus", "databaseName" : "Reactome", "id" : "R-HSA-205043" }, { "name" : "Constitutive Signaling by NOTCH1 PEST Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2644606" }, { "name" : "NOTCH2 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-2979096" }, { "name" : "EPH-ephrin mediated repulsion of cells", "databaseName" : "Reactome", "id" : "R-HSA-3928665" }, { "name" : "Nuclear signaling by ERBB4", "databaseName" : "Reactome", "id" : "R-HSA-1251985" }, { "name" : "Regulated proteolysis of p75NTR", "databaseName" : "Reactome", "id" : "R-HSA-193692" } ] } }, "locations" : [ { "start" : 4, "end" : 94, "hmmStart" : 3, "hmmEnd" : 93, "hmmLength" : 93, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 4.5E-31, "score" : 107.1, "envelopeStart" : 2, "envelopeEnd" : 94, "postProcessed" : true, "location-fragments" : [ { "start" : 4, "end" : 94, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-31, "score" : 107.2, "model-ac" : "PF10251" }, { "signature" : { "accession" : "PTHR16318", "name" : "GAMMA-SECRETASE SUBUNIT PEN-2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR019379", "name" : "Gamma_Secretase_Asp_P_PEN2", "description" : "Gamma-secretase aspartyl protease complex, presenilin enhancer-2 subunit", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Activated NOTCH1 Transmits Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-2122948" }, { "name" : "Noncanonical activation of NOTCH3", "databaseName" : "Reactome", "id" : "R-HSA-9017802" }, { "name" : "NOTCH3 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-9013507" }, { "name" : "Amyloid fiber formation", "databaseName" : "Reactome", "id" : "R-HSA-977225" }, { "name" : "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2894862" }, { "name" : "NOTCH4 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-9013700" }, { "name" : "NRIF signals cell death from the nucleus", "databaseName" : "Reactome", "id" : "R-HSA-205043" }, { "name" : "Constitutive Signaling by NOTCH1 PEST Domain Mutants", "databaseName" : "Reactome", "id" : "R-HSA-2644606" }, { "name" : "NOTCH2 Activation and Transmission of Signal to the Nucleus", "databaseName" : "Reactome", "id" : "R-HSA-2979096" }, { "name" : "EPH-ephrin mediated repulsion of cells", "databaseName" : "Reactome", "id" : "R-HSA-3928665" }, { "name" : "Nuclear signaling by ERBB4", "databaseName" : "Reactome", "id" : "R-HSA-1251985" }, { "name" : "Regulated proteolysis of p75NTR", "databaseName" : "Reactome", "id" : "R-HSA-193692" } ] } }, "locations" : [ { "start" : 2, "end" : 94, "hmmStart" : 10, "hmmEnd" : 101, "hmmLength" : 108, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 95, "location-fragments" : [ { "start" : 2, "end" : 94, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-24, "familyName" : "GAMMA-SECRETASE SUBUNIT PEN-2", "score" : 89.3, "model-ac" : "PTHR16318" } ], "xref" : [ { "name" : "XP_018910164.1 PREDICTED: gamma-secretase subunit pen-2 [Bemisia tabaci]", "id" : "XP_018910164.1" } ] },{ "sequence" : "MEKVVDRIMYARSQQRNFTKMPVTGGTPVTQEVAIAFRSIVFGTSVAPPRGEWLRTGFVFRDADKELAYGLKAPRNGCRGLLSVVQAYILKQLLFERKDFKKNEPVMQPEMLLRPSRGKQLEALWLAISDILWRIGEKTKAVVCLPQDQPYVSHSLNYFQDSVTEKLHIFEIANLEELQIFIKRYIHLFLEEPGPGALLLLYSAVATRGTKNVISDIMDEKGYLVTGAEEGSQSIIMLLLTGRATPYLHNGVVYVGDEEHYAIPQFGVLQRSEIGFLLFDEGVEEKAPGSRLKTPSLPIWVVCCLGHFGVIFNTNRELLRNYHAERRFELIYYTCGGSQCQLTVDTRHDGSSTQVSTSEDTASSSLANLEKLIHTKWQDAHIHWNGTSNFI", "md5" : "b7175cb4cfe7a554057074a9825cc074", "matches" : [ { "signature" : { "accession" : "PTHR12473", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR039785", "name" : "MINY3/4", "description" : "Deubiquitinating enzyme MINDY-3/4", "type" : "FAMILY", "goXRefs" : [ { "name" : "Lys48-specific deubiquitinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:1990380" }, { "name" : "protein K48-linked deubiquitination", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0071108" }, { "name" : "thiol-dependent ubiquitin-specific protease activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004843" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 388, "hmmStart" : 186, "hmmEnd" : 549, "hmmLength" : 552, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 391, "location-fragments" : [ { "start" : 14, "end" : 388, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-104, "familyName" : "", "score" : 353.1, "model-ac" : "PTHR12473" }, { "signature" : { "accession" : "SM01174", "name" : "DUF4205_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR025257", "name" : "MINDY-3/4_CD", "description" : "Deubiquitinating enzyme MINDY-3/4, conserved domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 38, "end" : 386, "hmmStart" : 1, "hmmEnd" : 438, "hmmLength" : 438, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-131, "score" : 452.1, "location-fragments" : [ { "start" : 38, "end" : 386, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-131, "score" : 452.1, "model-ac" : "SM01174" }, { "signature" : { "accession" : "PF13898", "name" : "DUF4205", "description" : "Domain of unknown function (DUF4205)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR025257", "name" : "MINDY-3/4_CD", "description" : "Deubiquitinating enzyme MINDY-3/4, conserved domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 38, "end" : 386, "hmmStart" : 1, "hmmEnd" : 351, "hmmLength" : 351, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-129, "score" : 432.3, "envelopeStart" : 38, "envelopeEnd" : 386, "postProcessed" : true, "location-fragments" : [ { "start" : 38, "end" : 386, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-129, "score" : 432.5, "model-ac" : "PF13898" }, { "signature" : { "accession" : "PTHR12473:SF4", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 388, "hmmStart" : 186, "hmmEnd" : 549, "hmmLength" : 552, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 391, "location-fragments" : [ { "start" : 14, "end" : 388, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-104, "familyName" : "", "score" : 353.1, "model-ac" : "PTHR12473:SF4" } ], "xref" : [ { "name" : "XP_018910121.1 PREDICTED: protein FAM188B2 isoform X5 [Bemisia tabaci]", "id" : "XP_018910121.1" } ] },{ "sequence" : "MAQCTPLILRIVASSVSVAGQAGKIIRDVMKKGELGIIDKGVNDLQTEADRSAQNFIISTLTKQFPGVTIIGEEEPSCYEALDNVTADSDTSVLQATCPPDLVAVSEKDVVIWVDPLDGTSEYTKGLLDHVTVLIGIAVGQRAIAGVIHQPFHNFKLCDENKIGRTIWGLQGYGVAGFKPIPPPSNKRIITTTRSHFTPEIQETLDAMCPDELLRVGGAGHKVILLMEGKAHAYVFASPGCKRWDTCAPEAVLRAMGGELTDMHGATYDYSKDTPHANTRGVLATALASDHEFYLKMVPQKIRELLI", "md5" : "12e76842ad027fdfafaa150ac804d4fa", "matches" : [ { "signature" : { "accession" : "PS00629", "name" : "IMP_1", "description" : "Inositol monophosphatase family signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR020583", "name" : "Inositol_monoP_metal-BS", "description" : "Inositol monophosphatase, metal-binding site", "type" : "BINDING_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 113, "end" : 125, "level" : "STRONG", "cigarAlignment" : "8M2I1M1I1M", "alignment" : "WVDPLDGTseYtK", "location-fragments" : [ { "start" : 113, "end" : 125, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00629" }, { "signature" : { "accession" : "cd01640", "name" : "IPPase", "description" : "IPPase", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 296, "sites" : [ { "description" : "active site", "numLocations" : 22, "siteLocations" : [ { "start" : 219, "end" : 219, "residue" : "A" }, { "start" : 115, "end" : 115, "residue" : "D" }, { "start" : 244, "end" : 244, "residue" : "W" }, { "start" : 234, "end" : 234, "residue" : "Y" }, { "start" : 193, "end" : 193, "residue" : "T" }, { "start" : 117, "end" : 117, "residue" : "L" }, { "start" : 119, "end" : 119, "residue" : "G" }, { "start" : 241, "end" : 241, "residue" : "C" }, { "start" : 50, "end" : 50, "residue" : "D" }, { "start" : 240, "end" : 240, "residue" : "G" }, { "start" : 74, "end" : 74, "residue" : "E" }, { "start" : 116, "end" : 116, "residue" : "P" }, { "start" : 122, "end" : 122, "residue" : "E" }, { "start" : 118, "end" : 118, "residue" : "D" }, { "start" : 73, "end" : 73, "residue" : "E" }, { "start" : 217, "end" : 217, "residue" : "G" }, { "start" : 218, "end" : 218, "residue" : "G" }, { "start" : 236, "end" : 236, "residue" : "F" }, { "start" : 222, "end" : 222, "residue" : "K" }, { "start" : 216, "end" : 216, "residue" : "V" }, { "start" : 245, "end" : 245, "residue" : "D" }, { "start" : 120, "end" : 120, "residue" : "T" } ] } ], "evalue" : 1.8781E-116, "score" : 335.447, "location-fragments" : [ { "start" : 11, "end" : 296, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01640" }, { "signature" : { "accession" : "PF00459", "name" : "Inositol_P", "description" : "Inositol monophosphatase family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000760", "name" : "Inositol_monophosphatase-like", "description" : "Inositol monophosphatase-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "inositol phosphate dephosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0046855" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 15, "end" : 291, "hmmStart" : 9, "hmmEnd" : 267, "hmmLength" : 272, "hmmBounds" : "INCOMPLETE", "evalue" : 1.8E-52, "score" : 178.6, "envelopeStart" : 9, "envelopeEnd" : 296, "postProcessed" : true, "location-fragments" : [ { "start" : 15, "end" : 291, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-52, "score" : 178.9, "model-ac" : "PF00459" }, { "signature" : { "accession" : "G3DSA:3.40.190.80", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 181, "end" : 307, "hmmStart" : 7, "hmmEnd" : 127, "hmmLength" : 136, "hmmBounds" : "COMPLETE", "evalue" : 7.0E-40, "score" : 137.9, "envelopeStart" : 181, "envelopeEnd" : 307, "postProcessed" : true, "location-fragments" : [ { "start" : 181, "end" : 307, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-40, "score" : 138.5, "model-ac" : "2wefA02" }, { "signature" : { "accession" : "PS00630", "name" : "IMP_2", "description" : "Inositol monophosphatase family signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR020550", "name" : "Inositol_monophosphatase_CS", "description" : "Inositol monophosphatase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "phosphatidylinositol phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0046854" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 244, "end" : 258, "level" : "STRONG", "cigarAlignment" : "2M1I3M1I3M3I2M", "alignment" : "WDtCAPeAVLramGG", "location-fragments" : [ { "start" : 244, "end" : 258, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00630" }, { "signature" : { "accession" : "SSF56655", "name" : "Carbohydrate phosphatase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 300, "hmmLength" : 304, "location-fragments" : [ { "start" : 11, "end" : 300, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.66E-65, "model-ac" : "0039685" }, { "signature" : { "accession" : "G3DSA:3.30.540.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 177, "hmmStart" : 10, "hmmEnd" : 179, "hmmLength" : 179, "hmmBounds" : "COMPLETE", "evalue" : 4.6E-50, "score" : 171.5, "envelopeStart" : 3, "envelopeEnd" : 177, "postProcessed" : true, "location-fragments" : [ { "start" : 3, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.5E-50, "score" : 171.9, "model-ac" : "1jp4A01" }, { "signature" : { "accession" : "PTHR43028:SF5", "name" : "3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 6, "end" : 304, "hmmStart" : 8, "hmmEnd" : 310, "hmmLength" : 314, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 306, "location-fragments" : [ { "start" : 6, "end" : 304, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-108, "familyName" : "3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1", "score" : 363.1, "model-ac" : "PTHR43028:SF5" }, { "signature" : { "accession" : "PTHR43028", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 6, "end" : 304, "hmmStart" : 8, "hmmEnd" : 310, "hmmLength" : 314, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 306, "location-fragments" : [ { "start" : 6, "end" : 304, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-108, "familyName" : "3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1", "score" : 363.1, "model-ac" : "PTHR43028" } ], "xref" : [ { "name" : "XP_018910112.1 PREDICTED: 3'(2'),5'-bisphosphate nucleotidase 1 [Bemisia tabaci]", "id" : "XP_018910112.1" } ] },{ "sequence" : "MYSLTLEPVIQLLVTEVTKKSRTWNRTNACPYCRPFILITNFTRHLKRNHAGEDEVLDLARIVAESDSKEDLKIRKKRRTELTEKLRLKANYAYNVAVMNKEVEGSLLPVRRSNCTDSVMNEENHATCAYCQGLFARNTLYLHVPICKMNTSKDLNTSGTKRRVLRTSAIMLSAGPKEASKELKELVFPRLQHGEVSLIAKSDPLIVQFASRMIKKHFEKGKINYIKNCMRDLARFFIEMKKIDSNLKNLEACFQVKQYNNVILTIQCMCGIDYDTNKVSSPSVAARLKGAIAKCIDIIYCNALMDQTDHVAIKSELDQFMHLLTTNWQYEISGRTNRAQKQNKMHKEEVLPDSQDILDACLKIEKHEVDLSRELMRNPCNLVYKNLTKLVIAHLIILGRKRPGEVCCAEVKDFNNRKSADKESNEEYIQVLSEEERKSYDALLSFHIIGKGTEPVCVILTRKMDDLIRLLIRYREKVSIDPENPLLFPQPDSELLYDGSKCIDYVKDLCKLRKPVHFNAIGLRHHMATKVQLMNKGEQFTEQVARQLGHSVNVHKKNYRLPLSVIQRGIVGHEMLKMTGGTSVASAPTGESKTQESDRINQCDMNSANLNENVETSETVNVSNVSASKSDSESSESDNDIVKIKERFRTRKEKTKKASQENQTLNHSLPAETFTHYSSESELSNFSEELDVQSKIKTLKKMRSDTNSLSKVKRTPWTHEEKKAVFRHLSHCIIAGSAVRQTDILKALKEEALCNRTVAQ", "md5" : "3c521f0b4711d2a415e80ae7ec21df5c", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 620, "end" : 643, "location-fragments" : [ { "start" : 620, "end" : 643, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00397", "name" : "DNA_BRE_C", "description" : "DNA_BRE_C", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 373, "end" : 551, "sites" : [ { "description" : "DNA binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 403, "end" : 403, "residue" : "P" }, { "start" : 388, "end" : 388, "residue" : "T" }, { "start" : 507, "end" : 507, "residue" : "K" }, { "start" : 402, "end" : 402, "residue" : "R" }, { "start" : 505, "end" : 505, "residue" : "Y" }, { "start" : 521, "end" : 521, "residue" : "I" } ] } ], "evalue" : 7.62447E-5, "score" : 41.6967, "location-fragments" : [ { "start" : 373, "end" : 551, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00397" }, { "signature" : { "accession" : "PTHR33480", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 17, "end" : 619, "hmmStart" : 177, "hmmEnd" : 753, "hmmLength" : 761, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 7, "envelopeEnd" : 627, "location-fragments" : [ { "start" : 17, "end" : 619, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-91, "familyName" : "FAMILY NOT NAMED", "score" : 310.3, "model-ac" : "PTHR33480" }, { "signature" : { "accession" : "SSF56349", "name" : "DNA breaking-rejoining enzymes", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011010", "name" : "DNA_brk_join_enz", "description" : "DNA breaking-rejoining enzyme, catalytic core", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 378, "end" : 552, "hmmLength" : 182, "location-fragments" : [ { "start" : 378, "end" : 552, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.61E-6, "model-ac" : "0034815" } ], "xref" : [ { "name" : "XP_018909975.1 PREDICTED: uncharacterized protein LOC109039089, partial [Bemisia tabaci]", "id" : "XP_018909975.1" } ] },{ "sequence" : "MTRRQEEQGLKMLLMAFAVAACCTVEARKTSRKPHIIIMLADDMGWNDVGFHGSNQIPTPNIDALAYNGLILNSHYTPALCTPSRAALMTGKYPIHLGMQHLVILEAEPWGLPLEEKMLPQYLKESGYATHAIGKWHLGFFRKEYTPTHRGFDSHFGYWQGFQDYYDHSVKATFAKYHGYDMRRNMSLDWSAQGKYSTDLFTDEAVRIINTHEREDPLFLYMAHLAPHTANTYEPFQAPDEEVVRFAHIEDPERRTYAAMVSKLDQSVGEVVSALRSRDMLDNSIIIFMSDNGAPTYGLHSNRGSNYPLRGIKETPYEGGVRGVAAVWSPLIKKRSRVANQLMHIADWLPTLHSAAGLESSLPKDLDGVDMWKALSEDLPSPRTELLHNIDDIGEVYSALRSGPWKYVKGSVSKGRTDSWYGESGRSNNLTDDEVRSYDVTAVLHSKAGAALGGFVTKQQIKTKEMRLNAINSVAANANYGNCTSYTTNKLAWRICTLDFPKFEDELRLLTARGVLALRAAAEVRCNESMAPRECDATKSACLFNIAADPCERTNLAAAEPDLVRILEERVAELRKTARAPLNKPSDPLADPHNWNDTWTNWHDALDQLNQVQVTPPKPDLKVVVLFAAVVAVLCVLGLILAVKFVAPYALVPSDQYSSPRKFRSFTFGLKRETEDFQKGSVVT", "md5" : "7102b361a9dc13526c135042516332d3", "matches" : [ { "signature" : { "accession" : "PTHR10342:SF264", "name" : "MIP05773P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 528, "end" : 615, "hmmStart" : 470, "hmmEnd" : 557, "hmmLength" : 575, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 485, "envelopeEnd" : 631, "location-fragments" : [ { "start" : 528, "end" : 615, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-220, "familyName" : "MIP05773P", "score" : 735.5, "model-ac" : "PTHR10342:SF264" }, { "signature" : { "accession" : "PF00884", "name" : "Sulfatase", "description" : "Sulfatase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000917", "name" : "Sulfatase_N", "description" : "Sulfatase, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "sulfuric ester hydrolase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008484" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 34, "end" : 357, "hmmStart" : 1, "hmmEnd" : 308, "hmmLength" : 309, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.2E-72, "score" : 244.1, "envelopeStart" : 34, "envelopeEnd" : 358, "postProcessed" : true, "location-fragments" : [ { "start" : 34, "end" : 357, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-72, "score" : 244.5, "model-ac" : "PF00884" }, { "signature" : { "accession" : "PTHR10342", "name" : "ARYLSULFATASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 449, "hmmStart" : 10, "hmmEnd" : 445, "hmmLength" : 575, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 6, "envelopeEnd" : 496, "location-fragments" : [ { "start" : 15, "end" : 449, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-220, "familyName" : "MIP05773P", "score" : 735.5, "model-ac" : "PTHR10342" }, { "signature" : { "accession" : "G3DSA:3.40.720.10", "name" : "Alkaline Phosphatase", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR017850", "name" : "Alkaline_phosphatase_core_sf", "description" : "Alkaline-phosphatase-like, core domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 34, "end" : 383, "hmmStart" : 1, "hmmEnd" : 395, "hmmLength" : 371, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.6E-150, "score" : 502.3, "envelopeStart" : 34, "envelopeEnd" : 446, "postProcessed" : true, "location-fragments" : [ { "start" : 34, "end" : 383, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-160, "score" : 536.8, "model-ac" : "1fsuA01" }, { "signature" : { "accession" : "PTHR10342", "name" : "ARYLSULFATASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 528, "end" : 615, "hmmStart" : 470, "hmmEnd" : 557, "hmmLength" : 575, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 485, "envelopeEnd" : 631, "location-fragments" : [ { "start" : 528, "end" : 615, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-220, "familyName" : "MIP05773P", "score" : 735.5, "model-ac" : "PTHR10342" }, { "signature" : { "accession" : "PS00149", "name" : "SULFATASE_2", "description" : "Sulfatases signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR024607", "name" : "Sulfatase_CS", "description" : "Sulfatase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 127, "end" : 137, "level" : "STRONG", "cigarAlignment" : "2M1I1M2I5M", "alignment" : "GYaThaIGKWH", "location-fragments" : [ { "start" : 127, "end" : 137, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00149" }, { "signature" : { "accession" : "PS00523", "name" : "SULFATASE_1", "description" : "Sulfatases signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR024607", "name" : "Sulfatase_CS", "description" : "Sulfatase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 79, "end" : 91, "level" : "STRONG", "cigarAlignment" : "7M2I4M", "alignment" : "ALCTPSRaaLMTG", "location-fragments" : [ { "start" : 79, "end" : 91, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00523" }, { "signature" : { "accession" : "PTHR10342:SF264", "name" : "MIP05773P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 449, "hmmStart" : 10, "hmmEnd" : 445, "hmmLength" : 575, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 6, "envelopeEnd" : 496, "location-fragments" : [ { "start" : 15, "end" : 449, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-220, "familyName" : "MIP05773P", "score" : 735.5, "model-ac" : "PTHR10342:SF264" }, { "signature" : { "accession" : "cd16029", "name" : "4-S", "description" : "4-S", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 34, "end" : 410, "sites" : [ { "description" : "Ca binding site", "numLocations" : 5, "siteLocations" : [ { "start" : 43, "end" : 43, "residue" : "D" }, { "start" : 291, "end" : 291, "residue" : "D" }, { "start" : 81, "end" : 81, "residue" : "C" }, { "start" : 42, "end" : 42, "residue" : "D" }, { "start" : 292, "end" : 292, "residue" : "N" } ] }, { "description" : "putative substrate binding site", "numLocations" : 7, "siteLocations" : [ { "start" : 228, "end" : 228, "residue" : "H" }, { "start" : 43, "end" : 43, "residue" : "D" }, { "start" : 137, "end" : 137, "residue" : "H" }, { "start" : 135, "end" : 135, "residue" : "K" }, { "start" : 81, "end" : 81, "residue" : "C" }, { "start" : 42, "end" : 42, "residue" : "D" }, { "start" : 292, "end" : 292, "residue" : "N" } ] }, { "description" : "putative active site", "numLocations" : 8, "siteLocations" : [ { "start" : 228, "end" : 228, "residue" : "H" }, { "start" : 43, "end" : 43, "residue" : "D" }, { "start" : 137, "end" : 137, "residue" : "H" }, { "start" : 291, "end" : 291, "residue" : "D" }, { "start" : 135, "end" : 135, "residue" : "K" }, { "start" : 81, "end" : 81, "residue" : "C" }, { "start" : 42, "end" : 42, "residue" : "D" }, { "start" : 292, "end" : 292, "residue" : "N" } ] } ], "evalue" : 0.0, "score" : 638.056, "location-fragments" : [ { "start" : 34, "end" : 410, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd16029" }, { "signature" : { "accession" : "PS51257", "name" : "PROKAR_LIPOPROTEIN", "description" : "Prokaryotic membrane lipoprotein lipid attachment site profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 22, "score" : 6.0, "alignment" : "MTRR-------------QEEQGLKMLLMAFAVAAC", "location-fragments" : [ { "start" : 1, "end" : 22, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51257" }, { "signature" : { "accession" : "G3DSA:3.30.1120.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 384, "end" : 427, "hmmStart" : 1, "hmmEnd" : 395, "hmmLength" : 121, "hmmBounds" : "INCOMPLETE", "evalue" : 4.6E-150, "score" : 502.3, "envelopeStart" : 34, "envelopeEnd" : 446, "postProcessed" : true, "location-fragments" : [ { "start" : 384, "end" : 427, "dc-status" : "CONTINUOUS" } ] }, { "start" : 521, "end" : 575, "hmmStart" : 390, "hmmEnd" : 444, "hmmLength" : 121, "hmmBounds" : "INCOMPLETE", "evalue" : 1.4E-7, "score" : 32.7, "envelopeStart" : 460, "envelopeEnd" : 576, "postProcessed" : true, "location-fragments" : [ { "start" : 521, "end" : 575, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-160, "score" : 536.8, "model-ac" : "1fsuA02" }, { "signature" : { "accession" : "SSF53649", "name" : "Alkaline phosphatase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR017850", "name" : "Alkaline_phosphatase_core_sf", "description" : "Alkaline-phosphatase-like, core domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 602, "hmmLength" : 492, "location-fragments" : [ { "start" : 32, "end" : 423, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 505, "end" : 602, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.37E-125, "model-ac" : "0037763" } ], "xref" : [ { "name" : "XP_018909943.1 PREDICTED: arylsulfatase B-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909943.1" } ] },{ "sequence" : "MVVKKELQKTEKILEEKRKENKQYRDLLDSEWATLRQKQKEVMESFPNHQTFIIENEKKRERAEHVIKVEKEKQEKFDSSINELKEKIKESLKIRDVMQSYVDQYKIYEDYLKSVVESLPEFNSIKEVIDRYRTLISVERELEERKGAEVAAMEGYRKSMVELTVSKSQEMMVLNNKLIELQSSHERASNQLNWFQDMLSVIDANASRLFVEHSI", "md5" : "81f626fea52198a98946c983f67a0ccc", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 171, "end" : 191, "location-fragments" : [ { "start" : 171, "end" : 191, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR21683:SF2", "name" : "CILIA AND FLAGELLA-ASSOCIATED PROTEIN 73", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4, "end" : 194, "hmmStart" : 30, "hmmEnd" : 222, "hmmLength" : 291, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 211, "location-fragments" : [ { "start" : 4, "end" : 194, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-38, "familyName" : "CILIA AND FLAGELLA-ASSOCIATED PROTEIN 73", "score" : 132.9, "model-ac" : "PTHR21683:SF2" }, { "signature" : { "accession" : "PTHR21683", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4, "end" : 194, "hmmStart" : 30, "hmmEnd" : 222, "hmmLength" : 291, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 211, "location-fragments" : [ { "start" : 4, "end" : 194, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-38, "familyName" : "CILIA AND FLAGELLA-ASSOCIATED PROTEIN 73", "score" : 132.9, "model-ac" : "PTHR21683" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 27, "location-fragments" : [ { "start" : 7, "end" : 27, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PF13863", "name" : "DUF4200", "description" : "Domain of unknown function (DUF4200)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR025252", "name" : "DUF4200", "description" : "Domain of unknown function DUF4200", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4, "end" : 117, "hmmStart" : 5, "hmmEnd" : 118, "hmmLength" : 119, "hmmBounds" : "INCOMPLETE", "evalue" : 1.7E-17, "score" : 63.9, "envelopeStart" : 2, "envelopeEnd" : 118, "postProcessed" : true, "location-fragments" : [ { "start" : 4, "end" : 117, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-17, "score" : 63.9, "model-ac" : "PF13863" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 67, "end" : 87, "location-fragments" : [ { "start" : 67, "end" : 87, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" } ], "xref" : [ { "name" : "XP_018909971.1 PREDICTED: coiled-coil domain-containing protein 42 homolog, partial [Bemisia tabaci]", "id" : "XP_018909971.1" } ] },{ "sequence" : "MSFEDYETLPTNNVLAHMTAGAFAGIMEHCIMYPMDSVKTRMQSLSPAANTGVTGIRDVFFRMVTTEGVWRPVKGIGVVVMGAGPAHAIYFSCYEAIKDNLTSRHFMNDAFSYGAAGCVSTVIHDGVMTPTDVVKQRLQMFNSPYKSIVDCIQRTYQTEGVKAFYRSYTTQLMMNIPFQSIHFMTYETATNFMNPERTYKPTAHMVSGAIAGGVAAAVTTPLDVCKTLLNTQEGERKISGLVNAIKAVYRLGGPFGYFRGLRARVLFQMPSTAICWSTYEFFKYMLISSKCYDSKTILAEKYHPKEDGLKYSQPGPPSVSEPESWVSNVGRELPAISSNSHLFNNSLAFTTVHKDTVTNPNMLDFTRS", "md5" : "6d2b71e0633dad6c680788d35bbc950a", "matches" : [ { "signature" : { "accession" : "PTHR45758", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4, "end" : 288, "hmmStart" : 50, "hmmEnd" : 344, "hmmLength" : 353, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 296, "location-fragments" : [ { "start" : 4, "end" : 288, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-126, "familyName" : "MITOFERRIN-2", "score" : 422.8, "model-ac" : "PTHR45758" }, { "signature" : { "accession" : "G3DSA:1.50.40.10", "name" : "Mitochondrial carrier domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR023395", "name" : "Mt_carrier_dom_sf", "description" : "Mitochondrial carrier domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 142, "hmmStart" : 109, "hmmEnd" : 240, "hmmLength" : 297, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.6E-30, "score" : 105.8, "envelopeStart" : 2, "envelopeEnd" : 144, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 142, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-73, "score" : 247.0, "model-ac" : "1okcA00" }, { "signature" : { "accession" : "SSF103506", "name" : "Mitochondrial carrier", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR023395", "name" : "Mt_carrier_dom_sf", "description" : "Mitochondrial carrier domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 12, "end" : 282, "hmmLength" : 292, "location-fragments" : [ { "start" : 12, "end" : 282, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.24E-72, "model-ac" : "0048588" }, { "signature" : { "accession" : "PF00153", "name" : "Mito_carr", "description" : "Mitochondrial carrier protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018108", "name" : "Mitochondrial_sb/sol_carrier", "description" : "Mitochondrial substrate/solute carrier", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 111, "end" : 194, "hmmStart" : 6, "hmmEnd" : 94, "hmmLength" : 97, "hmmBounds" : "INCOMPLETE", "evalue" : 5.0E-20, "score" : 71.2, "envelopeStart" : 108, "envelopeEnd" : 197, "postProcessed" : true, "location-fragments" : [ { "start" : 111, "end" : 194, "dc-status" : "CONTINUOUS" } ] }, { "start" : 199, "end" : 288, "hmmStart" : 3, "hmmEnd" : 95, "hmmLength" : 97, "hmmBounds" : "INCOMPLETE", "evalue" : 3.6E-20, "score" : 71.7, "envelopeStart" : 197, "envelopeEnd" : 290, "postProcessed" : true, "location-fragments" : [ { "start" : 199, "end" : 288, "dc-status" : "CONTINUOUS" } ] }, { "start" : 12, "end" : 103, "hmmStart" : 3, "hmmEnd" : 95, "hmmLength" : 97, "hmmBounds" : "INCOMPLETE", "evalue" : 3.0E-19, "score" : 68.8, "envelopeStart" : 10, "envelopeEnd" : 105, "postProcessed" : true, "location-fragments" : [ { "start" : 12, "end" : 103, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-63, "score" : 210.9, "model-ac" : "PF00153" }, { "signature" : { "accession" : "G3DSA:1.50.40.10", "name" : "Mitochondrial carrier domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR023395", "name" : "Mt_carrier_dom_sf", "description" : "Mitochondrial carrier domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 143, "end" : 300, "hmmStart" : 41, "hmmEnd" : 199, "hmmLength" : 295, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.5E-37, "score" : 130.9, "envelopeStart" : 140, "envelopeEnd" : 300, "postProcessed" : true, "location-fragments" : [ { "start" : 143, "end" : 300, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-68, "score" : 230.6, "model-ac" : "4c9gA00" }, { "signature" : { "accession" : "PS50920", "name" : "SOLCAR", "description" : "Solute carrier (Solcar) repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR018108", "name" : "Mitochondrial_sb/sol_carrier", "description" : "Mitochondrial substrate/solute carrier", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 12, "end" : 100, "score" : 19.939, "alignment" : "NNVLAHMTAGAFAGIMEHCIMYPMDSVKTRMQ--SLSPAANTGVTGIRDVFFRMVTTEGVWRPVKGIGVVVMGAGPAHAIYFSCYEAIKDN", "location-fragments" : [ { "start" : 12, "end" : 100, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50920" }, { "signature" : { "accession" : "PS50920", "name" : "SOLCAR", "description" : "Solute carrier (Solcar) repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR018108", "name" : "Mitochondrial_sb/sol_carrier", "description" : "Mitochondrial substrate/solute carrier", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 199, "end" : 285, "score" : 19.274, "alignment" : "YKPTAHMVSGAIAGGVAAAVTTPLDVCKTLLNTQ----EGERKISGLVNAIKAVYRLGGPFGYFRGLRARVLFQMPSTAICWSTYEFFKYM", "location-fragments" : [ { "start" : 199, "end" : 285, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50920" }, { "signature" : { "accession" : "PS50920", "name" : "SOLCAR", "description" : "Solute carrier (Solcar) repeat profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR018108", "name" : "Mitochondrial_sb/sol_carrier", "description" : "Mitochondrial substrate/solute carrier", "type" : "REPEAT", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 108, "end" : 192, "score" : 21.719, "alignment" : "NDAFSYGAAGCVSTVIHDGVMTPTDVVKQRLQM------FNSPYKSIVDCIQRTYQTEGVKAFYRSYTTQLMMNIPFQSIHFMTYETATNF", "location-fragments" : [ { "start" : 108, "end" : 192, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50920" }, { "signature" : { "accession" : "PTHR45758:SF1", "name" : "MITOFERRIN-2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 4, "end" : 288, "hmmStart" : 50, "hmmEnd" : 344, "hmmLength" : 353, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 296, "location-fragments" : [ { "start" : 4, "end" : 288, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.3E-126, "familyName" : "MITOFERRIN-2", "score" : 422.8, "model-ac" : "PTHR45758:SF1" } ], "xref" : [ { "name" : "XP_018910484.1 PREDICTED: mitoferrin-1 isoform X1 [Bemisia tabaci]", "id" : "XP_018910484.1" } ] },{ "sequence" : "MYLITIIIIRQHFEIPLLIIGIMKELTRLYAVLLFPPEKGTEEETVNVVPQSWVKKEGKICLWPKIKNPKKLIEECTSPVDVACEWQEFEYKAKCKENIEGYSKAKIVEKNVLDEKESNLSEISDVPKKRPRMPKNPFSPSAMQSTSSSPKSCVSLEEINDADVESEENTTPIRRRSFRQAQISPLPEDDSPVGSNQTLTPKYPTPPTKRVTPIRKSHCNASRSLFADGEGSAKNTKPPSNIRLVKTCKSHQNIAKEPSAQVSSNSDHKKSRQSHTSKTIAEESFTNPTPELSSSFFAHSDHEKSRQSHTSKTNAEECFMNPTSESSSSFFAHSDHEKSRQSHTSKTNAEECFMSPTSESSSGPSASLDFSNLFMPTSKSLTTFHTQWRKMNAQQKDLYQAETLFVLRRTLPLMVTKLGPGIPGTSAAIDSIKAHPNLTCFPINDEDDLNKAEKLLKMKGWKQKLETLLLSKKCKDLRETARAMCSFLFTDQFGSGYSMVGQKKKKSFVQLPLVTLLKRKTQNTH", "md5" : "8cc55f7b1858344db187a8fbb0016612", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 278, "end" : 296, "location-fragments" : [ { "start" : 278, "end" : 296, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 346, "end" : 360, "location-fragments" : [ { "start" : 346, "end" : 360, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 138, "end" : 155, "location-fragments" : [ { "start" : 138, "end" : 155, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 189, "end" : 205, "location-fragments" : [ { "start" : 189, "end" : 205, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 234, "end" : 267, "location-fragments" : [ { "start" : 234, "end" : 267, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 331, "end" : 345, "location-fragments" : [ { "start" : 331, "end" : 345, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 297, "end" : 311, "location-fragments" : [ { "start" : 297, "end" : 311, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 119, "end" : 360, "location-fragments" : [ { "start" : 119, "end" : 360, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF16064", "name" : "DUF4806", "description" : "Domain of unknown function (DUF4806)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR032071", "name" : "DUF4806", "description" : "Domain of unknown function DUF4806", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 441, "end" : 509, "hmmStart" : 7, "hmmEnd" : 78, "hmmLength" : 90, "hmmBounds" : "INCOMPLETE", "evalue" : 9.0E-6, "score" : 25.9, "envelopeStart" : 437, "envelopeEnd" : 522, "postProcessed" : true, "location-fragments" : [ { "start" : 441, "end" : 509, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-6, "score" : 27.5, "model-ac" : "PF16064" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 312, "end" : 330, "location-fragments" : [ { "start" : 312, "end" : 330, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910541.1 PREDICTED: uncharacterized protein LOC109039501 isoform X3 [Bemisia tabaci]", "id" : "XP_018910541.1" } ] },{ "sequence" : "MSSSCSPADQLQAAAQDGRKSELSIASARASVMLYDDVSKKWIPSGTSSGVSKVHIFQHQVNNTFRVVGRKLKDHEVVINCVILKSLKYNQATATFHQWRDNKQVYGLNFSNKEDADAFARAMMYAVEVLGSASNRPARVDPGPPPTYEQAVSQYDEDMGYSHNPVVGHRMYHQVSPGGPPRIDVSPNSRTMTREDVAIIQERRVSSQSQISSPSTASSPGGLNNVGVSGTQASPVPPQVPGHHRTSSAPPAPQPPPMSLATPSVAPVAPPCPPPCPPLPPQPISTSVEPEASMSRSNSSDNQDPGSLAAQLQSARLRRANKQSAENSGSSTSSNGSAGNYGTLRGTTGMASMLDEMTRTLARRRAAVEKTQTDVVQDGDGVSGDAKKSWNSPNSKSGCESPKPVRKQLANSSEELVGCGKVNGSVSELESLKQEILKEMKKEISRMKQDIIDAIKIELNRR", "md5" : "bfc925bef56c0aad69c644a7376a2ad8", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 426, "end" : 457, "location-fragments" : [ { "start" : 426, "end" : 457, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "SSF118370", "name" : "Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038023", "name" : "VASP_sf", "description" : "VASP tetramerisation domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Generation of second messenger molecules", "databaseName" : "Reactome", "id" : "R-HSA-202433" }, { "name" : "Signaling by ROBO receptors", "databaseName" : "Reactome", "id" : "R-HSA-376176" } ] } }, "locations" : [ { "start" : 427, "end" : 462, "hmmLength" : 42, "location-fragments" : [ { "start" : 427, "end" : 462, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.19E-11, "model-ac" : "0053530" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 387, "end" : 401, "location-fragments" : [ { "start" : 387, "end" : 401, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF50729", "name" : "PH domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 140, "hmmLength" : 145, "location-fragments" : [ { "start" : 18, "end" : 140, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.07E-37, "model-ac" : "0047292" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 286, "end" : 347, "location-fragments" : [ { "start" : 286, "end" : 347, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00461", "name" : "WH1_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000697", "name" : "WH1/EVH1_dom", "description" : "WH1/EVH1 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 20, "end" : 127, "hmmStart" : 1, "hmmEnd" : 124, "hmmLength" : 124, "hmmBounds" : "COMPLETE", "evalue" : 4.5E-39, "score" : 145.8, "location-fragments" : [ { "start" : 20, "end" : 127, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-39, "score" : 145.8, "model-ac" : "SM00461" }, { "signature" : { "accession" : "PF08776", "name" : "VASP_tetra", "description" : "VASP tetramerisation domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR014885", "name" : "VASP_tetra", "description" : "VASP tetramerisation", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Generation of second messenger molecules", "databaseName" : "Reactome", "id" : "R-HSA-202433" }, { "name" : "Signaling by ROBO receptors", "databaseName" : "Reactome", "id" : "R-HSA-376176" } ] } }, "locations" : [ { "start" : 427, "end" : 462, "hmmStart" : 2, "hmmEnd" : 37, "hmmLength" : 37, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 9.0E-14, "score" : 50.8, "envelopeStart" : 426, "envelopeEnd" : 462, "postProcessed" : true, "location-fragments" : [ { "start" : 427, "end" : 462, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-14, "score" : 51.8, "model-ac" : "PF08776" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 202, "end" : 236, "location-fragments" : [ { "start" : 202, "end" : 236, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd01207", "name" : "EVH1_Ena_VASP-like", "description" : "EVH1_Ena_VASP-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 130, "sites" : [ { "description" : "proline-rich peptide binding site", "numLocations" : 7, "siteLocations" : [ { "start" : 90, "end" : 90, "residue" : "N" }, { "start" : 88, "end" : 88, "residue" : "K" }, { "start" : 42, "end" : 42, "residue" : "W" }, { "start" : 100, "end" : 100, "residue" : "R" }, { "start" : 35, "end" : 35, "residue" : "Y" }, { "start" : 98, "end" : 98, "residue" : "Q" }, { "start" : 96, "end" : 96, "residue" : "F" } ] } ], "evalue" : 2.99422E-67, "score" : 208.701, "location-fragments" : [ { "start" : 24, "end" : 130, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01207" }, { "signature" : { "accession" : "G3DSA:1.20.5.1160", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042180", "name" : "IF_rod_dom_coil1B", "description" : "Intermediate filament, rod domain, coil 1B", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 423, "end" : 462, "hmmStart" : 7, "hmmEnd" : 42, "hmmLength" : 45, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-9, "score" : 38.2, "envelopeStart" : 423, "envelopeEnd" : 462, "postProcessed" : true, "location-fragments" : [ { "start" : 423, "end" : 462, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-9, "score" : 39.2, "model-ac" : "1useA00" }, { "signature" : { "accession" : "PF00568", "name" : "WH1", "description" : "WH1 domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000697", "name" : "WH1/EVH1_dom", "description" : "WH1/EVH1 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 17, "end" : 124, "hmmStart" : 4, "hmmEnd" : 108, "hmmLength" : 111, "hmmBounds" : "INCOMPLETE", "evalue" : 2.9E-33, "score" : 114.1, "envelopeStart" : 14, "envelopeEnd" : 127, "postProcessed" : true, "location-fragments" : [ { "start" : 17, "end" : 124, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-33, "score" : 114.7, "model-ac" : "PF00568" }, { "signature" : { "accession" : "PTHR11202", "name" : "VASODILATOR-STIMULATED PHOSPHOPROTEIN/SPROUTY PROTEIN EVH1 DOMAIN CONTAINING PROTEIN 3", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 21, "end" : 461, "hmmStart" : 2, "hmmEnd" : 469, "hmmLength" : 469, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 20, "envelopeEnd" : 461, "location-fragments" : [ { "start" : 21, "end" : 461, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-89, "familyName" : "VASODILATOR-STIMULATED PHOSPHOPROTEIN/SPROUTY PROTEIN EVH1 DOMAIN CONTAINING PROTEIN 3", "score" : 304.2, "model-ac" : "PTHR11202" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 248, "end" : 285, "location-fragments" : [ { "start" : 248, "end" : 285, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:2.30.29.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR011993", "name" : "PH-like_dom_sf", "description" : "PH-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 136, "hmmStart" : 7, "hmmEnd" : 124, "hmmLength" : 130, "hmmBounds" : "COMPLETE", "evalue" : 9.5E-43, "score" : 147.1, "envelopeStart" : 14, "envelopeEnd" : 136, "postProcessed" : true, "location-fragments" : [ { "start" : 14, "end" : 136, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-43, "score" : 147.9, "model-ac" : "3syxA00" }, { "signature" : { "accession" : "PS50229", "name" : "WH1", "description" : "WH1 domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000697", "name" : "WH1/EVH1_dom", "description" : "WH1/EVH1 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 17, "end" : 130, "score" : 19.899, "alignment" : "DGRKSELSIASARASVMLYDDVSKK-WIPSGTSsGVSkVHIFQHQVNNTFRVVGRKLK-DHEVVINCVILKSLKYNQATATFHQWRDNKQVYGLNFSNKEDADAFARAMMYAVEVL", "location-fragments" : [ { "start" : 17, "end" : 130, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50229" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 174, "end" : 414, "location-fragments" : [ { "start" : 174, "end" : 414, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909643.1 PREDICTED: protein enabled isoform X1 [Bemisia tabaci]", "id" : "XP_018909643.1" } ] },{ "sequence" : "MSERKQGETKKQRMSEAQKTHLITYMVDHSYFAKHGVDPGPNGSDAGAKRWQKLTNELNAIGAATKDASGWKQTWSDMKLRIKKIAAGITNLPTGNSGKPPKKLKPEEELVYHLCGGKDFIGAGTEEELGIALATQQQPQPALDDDADYSWLPPPPPELVREGDEESEDADMPDEQTDTYITDTETIEFDFPELGIQSITLPTSTAPKNSVNLSCQRTQRNNNPEKEQVKSMIPPEIPPKTPQSTPKPAPHSLPSCSKENGMYVGDSFRYHRNCSILSEKMHLLSLI", "md5" : "f1a38d2f4af43366e4af330371cc6150", "matches" : [ { "signature" : { "accession" : "PTHR23098", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR026753", "name" : "NAIF1", "description" : "Nuclear apoptosis-inducing factor 1", "type" : "FAMILY", "goXRefs" : [ { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" }, { "name" : "apoptotic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006915" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 251, "hmmStart" : 54, "hmmEnd" : 261, "hmmLength" : 373, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 267, "location-fragments" : [ { "start" : 6, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.6E-12, "familyName" : "FAMILY NOT NAMED", "score" : 48.2, "model-ac" : "PTHR23098" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 235, "end" : 249, "location-fragments" : [ { "start" : 235, "end" : 249, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 217, "end" : 258, "location-fragments" : [ { "start" : 217, "end" : 258, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 135, "end" : 175, "location-fragments" : [ { "start" : 135, "end" : 175, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF13873", "name" : "Myb_DNA-bind_5", "description" : "Myb/SANT-like DNA-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR028002", "name" : "Myb_DNA-bind_5", "description" : "Myb/SANT-like DNA-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 85, "hmmStart" : 1, "hmmEnd" : 75, "hmmLength" : 78, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 9.5E-9, "score" : 35.2, "envelopeStart" : 10, "envelopeEnd" : 87, "postProcessed" : true, "location-fragments" : [ { "start" : 10, "end" : 85, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-9, "score" : 36.1, "model-ac" : "PF13873" } ], "xref" : [ { "name" : "XP_018909953.1 PREDICTED: uncharacterized protein LOC109039075 [Bemisia tabaci]", "id" : "XP_018909953.1" } ] },{ "sequence" : "MFYEVKDKRIESATQQTKWWVTAGFCGVVVTGAFIGVTLWLGARQQNTESIITDRILNSGDNFNSFNSKFDVLSRPAPPPVVPGPAEFPKDPAEERRPPSFPPTNKKAKIEKVVDFMNGETVSTSTEAPRFPTYEQGFKPIVPNVRKHVVDSTESEELAEGPDPMEDIYPTGGKTDHQPVAKKSEAIYPAHEWIEEEKVHEVDSLYKPDTPVAPKHNYKFDEVYESQMTEMESRRDNLKPADQRDGKFKLKTIPAFTYMKENKYAEADIPGAVSEDYPYYYQKDQEFHGPNYDGVAPEDAESPLVAFLKKRLKDLNEWFTKNSGATSPDWSDLLTAVNQSLYNKNTSMLFNKFKEMYYNSSSDVQEVPLSSLIYPKNPAGIANNSNLISFGLLAIDLFLLHNVQQIAWNEENDIRVEMLKDPDIMALNALFLPPEKILQMKNPNSRFFTEQEDESKHGALHELMEFVNGGLRAVLNLGKAYRSSTRGVARSNGVNTLDCIWTLYCRNLDKTAKLNGPYGFLAKMNSLGLRLMMGEFPVERAFENLIRESTRGWRELDCQKLFPRCDAEEAKEVVIQTALGQNVPK", "md5" : "56f0276e7b2b813baef3483e93fe0bf0", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 76, "end" : 107, "location-fragments" : [ { "start" : 76, "end" : 107, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 89, "end" : 107, "location-fragments" : [ { "start" : 89, "end" : 107, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910204.1 PREDICTED: uncharacterized protein LOC109039249 [Bemisia tabaci]", "id" : "XP_018910204.1" } ] },{ "sequence" : "MNSYNLHARLFVLFTGYVVCQAASPGSPVTSKNIPPYIKQCREADPKLSECIIQAVNHLRPYLVRGIPDIQLPSVEPFRMEPFSLALATGPDGYKITLRDIDLRGASNFTITKLKLSRGSQPFEAKIRIPALVMDSHYSSSGVLIVIPASGNGTFHADFGDILATVKGYMSTVKEERTKRDYFHLDKLDLDLNIKKARMSVSKVFNNNKILVEATNLFLEANGQEVLQAMMPQLRGKLSNVFKGIVNQLLSNVPRDVMVI", "md5" : "56a73421bbdc9eca4e923f633b8bb946", "matches" : [ { "signature" : { "accession" : "PTHR11008", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 256, "hmmStart" : 11, "hmmEnd" : 232, "hmmLength" : 246, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 260, "location-fragments" : [ { "start" : 19, "end" : 256, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-63, "familyName" : "", "score" : 216.3, "model-ac" : "PTHR11008" }, { "signature" : { "accession" : "SM00700", "name" : "jhbp", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR010562", "name" : "Haemolymph_juvenile_hormone-bd", "description" : "Haemolymph juvenile hormone binding", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 259, "hmmStart" : 1, "hmmEnd" : 243, "hmmLength" : 243, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-57, "score" : 205.6, "location-fragments" : [ { "start" : 32, "end" : 259, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-57, "score" : 205.6, "model-ac" : "SM00700" }, { "signature" : { "accession" : "G3DSA:3.15.10.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR038606", "name" : "To_sf", "description" : "Takeout superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 259, "hmmStart" : 5, "hmmEnd" : 214, "hmmLength" : 220, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-43, "score" : 150.8, "envelopeStart" : 37, "envelopeEnd" : 259, "postProcessed" : true, "location-fragments" : [ { "start" : 37, "end" : 259, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-43, "score" : 151.2, "model-ac" : "3e8tA00" }, { "signature" : { "accession" : "PF06585", "name" : "JHBP", "description" : "Haemolymph juvenile hormone binding protein (JHBP)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR010562", "name" : "Haemolymph_juvenile_hormone-bd", "description" : "Haemolymph juvenile hormone binding", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 23, "end" : 258, "hmmStart" : 9, "hmmEnd" : 237, "hmmLength" : 239, "hmmBounds" : "INCOMPLETE", "evalue" : 3.7E-64, "score" : 216.2, "envelopeStart" : 14, "envelopeEnd" : 260, "postProcessed" : true, "location-fragments" : [ { "start" : 23, "end" : 258, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-64, "score" : 216.5, "model-ac" : "PF06585" }, { "signature" : { "accession" : "PTHR11008:SF9", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 256, "hmmStart" : 11, "hmmEnd" : 232, "hmmLength" : 246, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 5, "envelopeEnd" : 260, "location-fragments" : [ { "start" : 19, "end" : 256, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-63, "familyName" : "", "score" : 216.3, "model-ac" : "PTHR11008:SF9" } ], "xref" : [ { "name" : "XP_018910406.1 PREDICTED: uncharacterized protein LOC109039388 [Bemisia tabaci]", "id" : "XP_018910406.1" } ] },{ "sequence" : "MRKELRCIDFFVSILLIAASCAHGHQSKNHSEIDNPVVEFLNAKNEQPLRRINVNEHFDPLSNNQLKAELFSTDSCEVKDGHYSCCTILKLAAMDVREPVCIDFSPKNRSTEISTLKENVELFETTLSVGMTRASMTQRFDLKPGDYLQNISFPLCIPWFPVITVCVNVHNITYDFTNMSIRSCFMLTVGIVNFPINLFALDLDCIKYANRTIVKEPLNHQTLQSNQTVKPHELDYPNKEHSTFNSQISDLRPNVVQNSHRKGVYFEDRPKRSMSSVQSSPDRTTDPSMNSHLSSLPPKQFKQNNITTSDLKKIKRSPQSQDPRPVGQPAIPLRQLETRKEKRDVPKLPPRREYLPDDHRLRNRQQQSRQFLAVLNLERTWPHQFFIR", "md5" : "16e2a9572a03ea5bcc3a08ace7cdda9f", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 335, "end" : 363, "location-fragments" : [ { "start" : 335, "end" : 363, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 272, "end" : 314, "location-fragments" : [ { "start" : 272, "end" : 314, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 240, "end" : 256, "location-fragments" : [ { "start" : 240, "end" : 256, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 224, "end" : 363, "location-fragments" : [ { "start" : 224, "end" : 363, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51257", "name" : "PROKAR_LIPOPROTEIN", "description" : "Prokaryotic membrane lipoprotein lipid attachment site profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 21, "score" : 7.0, "alignment" : "MRKE-LR-------------CIDFFVSILLIAASC", "location-fragments" : [ { "start" : 1, "end" : 21, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51257" } ], "xref" : [ { "name" : "XP_018909699.1 PREDICTED: uncharacterized protein LOC109038893 isoform X1 [Bemisia tabaci]", "id" : "XP_018909699.1" }, { "name" : "XP_018909700.1 PREDICTED: uncharacterized protein LOC109038893 isoform X1 [Bemisia tabaci]", "id" : "XP_018909700.1" } ] },{ "sequence" : "MTSENDIKPAKLTTALKQILTEVDFIIWDEASMILSTAFQIVNVTLQDLMRNNDPFGGKAVCLGGDFRQLLPVVKKGSRNQIVKSALISSPLWKHFKIFHLKKNMRANNEEFSEWLLQIGNGKKEIVEFPSEMICNENIVDSIFKEYNEETLKTSILLASRNCEVDRLNEEVLSKMEGETIVSEGFSWATAVDGDLTDQDELTLRYQPEYLASLNPSGMPSQNLKLKEGAVVMLLRNICIEDGLCNGTRLIVLKINKYILHCSILTGEKKGKIVSLPKITLNTKEQTNLPFVLNRKQFPVRLAFAMTISKSQGQSFDRVGIFIDKERPMFAHGQLYVALSRCRTKEGLKIKIINFDDDKNKNTAMNIVYQEVLH", "md5" : "072f3134272209f07bdcdb48c2fe3d36", "matches" : [ { "signature" : { "accession" : "cd18809", "name" : "SF1_C_RecD", "description" : "SF1_C_RecD", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 293, "end" : 348, "sites" : [ { "description" : "ATP binding site", "numLocations" : 1, "siteLocations" : [ { "start" : 313, "end" : 313, "residue" : "G" } ] } ], "evalue" : 1.44832E-15, "score" : 69.1275, "location-fragments" : [ { "start" : 293, "end" : 348, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18809" }, { "signature" : { "accession" : "PTHR23274", "name" : "DNA HELICASE-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 17, "end" : 362, "hmmStart" : 116, "hmmEnd" : 355, "hmmLength" : 361, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 371, "location-fragments" : [ { "start" : 17, "end" : 362, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-59, "familyName" : "DNA HELICASE-RELATED", "score" : 204.7, "model-ac" : "PTHR23274" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 55, "end" : 348, "hmmLength" : 246, "location-fragments" : [ { "start" : 55, "end" : 123, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 151, "end" : 183, "dc-status" : "NC_TERMINAL_DISC" }, { "start" : 220, "end" : 348, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 7.83E-39, "model-ac" : "0050357" }, { "signature" : { "accession" : "PF02689", "name" : "Herpes_Helicase", "description" : "Helicase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR003840", "name" : "DNA_helicase", "description" : "DNA helicase", "type" : "FAMILY", "goXRefs" : [ { "name" : "helicase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004386" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 303, "end" : 361, "hmmStart" : 731, "hmmEnd" : 788, "hmmLength" : 809, "hmmBounds" : "INCOMPLETE", "evalue" : 2.9E-6, "score" : 25.5, "envelopeStart" : 281, "envelopeEnd" : 370, "postProcessed" : true, "location-fragments" : [ { "start" : 303, "end" : 361, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-6, "score" : 26.4, "model-ac" : "PF02689" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 117, "hmmStart" : 129, "hmmEnd" : 201, "hmmLength" : 216, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-11, "score" : 46.3, "envelopeStart" : 3, "envelopeEnd" : 117, "postProcessed" : true, "location-fragments" : [ { "start" : 3, "end" : 117, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-12, "score" : 47.3, "model-ac" : "3e1sA02" }, { "signature" : { "accession" : "cd18037", "name" : "DEXSc_Pif1_like", "description" : "DEXSc_Pif1_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 106, "sites" : [ { "description" : "DEAD box helicase motif", "numLocations" : 4, "siteLocations" : [ { "start" : 30, "end" : 30, "residue" : "E" }, { "start" : 31, "end" : 31, "residue" : "A" }, { "start" : 29, "end" : 29, "residue" : "D" }, { "start" : 32, "end" : 32, "residue" : "S" } ] } ], "evalue" : 3.52294E-10, "score" : 56.4883, "location-fragments" : [ { "start" : 15, "end" : 106, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18037" }, { "signature" : { "accession" : "PF05970", "name" : "PIF1", "description" : "PIF1-like helicase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR010285", "name" : "DNA_helicase_pif1-like", "description" : "DNA helicase Pif1-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "telomere maintenance", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0000723" }, { "name" : "DNA helicase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003678" }, { "name" : "DNA repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006281" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 11, "end" : 254, "hmmStart" : 91, "hmmEnd" : 363, "hmmLength" : 364, "hmmBounds" : "INCOMPLETE", "evalue" : 5.8E-64, "score" : 216.5, "envelopeStart" : 2, "envelopeEnd" : 255, "postProcessed" : true, "location-fragments" : [ { "start" : 11, "end" : 254, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-64, "score" : 217.0, "model-ac" : "PF05970" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 199, "end" : 350, "hmmStart" : 109, "hmmEnd" : 156, "hmmLength" : 173, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-7, "score" : 33.3, "envelopeStart" : 199, "envelopeEnd" : 350, "postProcessed" : true, "location-fragments" : [ { "start" : 199, "end" : 350, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-7, "score" : 33.9, "model-ac" : "1w36D03" } ], "xref" : [ { "name" : "XP_018910137.1 PREDICTED: ATP-dependent DNA helicase PIF1-like [Bemisia tabaci]", "id" : "XP_018910137.1" } ] },{ "sequence" : "MELENIVANTVYLKAREGGTDSNKGKSKKWKKILQFPHISHCLFLKNQIDFRYSYIVDQQPIGRLLFRQFCQEVCPQYHTHNVFLDSVEQYEVESDENRNEQARSLFDKHLETNAPEPVEVISSEIIEQCRERLTSGCRELFTHCSDVVKTFLAGEPFDAFKASMYCNRYLQWKWLERQPVTYKTFRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMVLREKQILQKINSKFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGDPGFDIPRARFYAAEVLCGLEHLHYQGLVYMDCKPENILLDDAGHVRISDLGLAAEIPEGEMVQGRVGTAGYMAPEVIDNGVYAFSPDWFSFGCLIYEMIEGQAPFRGRKEKVKREEVDRRAKEDQEKYSNKFTEEAKSLCKQLLKKSHKVRLGCHSGRHGAREVKQHEFFKCLNWKRIEAGMWEPPFVPDPHAVYAKDVLDIEQFSTVKGVNLDATDDTFYSKFNTGSVSIPWQTEMIETGCFKELNIFGPNATPTPDLVVDTCYEPEKKGCFPCSKKKKKLNRTKPLPISERFPRSMSNIKLEEVNS", "md5" : "9c61b0b6533d04cd0410feeaf9132216", "matches" : [ { "signature" : { "accession" : "PS51285", "name" : "AGC_KINASE_CTER", "description" : "AGC-kinase C-terminal domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000961", "name" : "AGC-kinase_C", "description" : "AGC-kinase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein serine/threonine kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004674" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 452, "end" : 517, "score" : 9.428, "alignment" : "KCLNWKRIEAGMWEPPFVPDPHavyakDVLDIEQFSTVkgvNLDAT--------------DDTFYSKFNTGSVSIPWQTE", "location-fragments" : [ { "start" : 452, "end" : 517, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51285" }, { "signature" : { "accession" : "SSF48097", "name" : "Regulator of G-protein signaling, RGS", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036305", "name" : "RGS_sf", "description" : "RGS domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 181, "hmmLength" : 157, "location-fragments" : [ { "start" : 32, "end" : 181, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.09E-34, "model-ac" : "0041925" }, { "signature" : { "accession" : "G3DSA:1.10.167.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 74, "end" : 153, "hmmStart" : 1, "hmmEnd" : 530, "hmmLength" : 80, "hmmBounds" : "INCOMPLETE", "evalue" : 6.1E-265, "score" : 881.7, "envelopeStart" : 3, "envelopeEnd" : 538, "postProcessed" : true, "location-fragments" : [ { "start" : 74, "end" : 153, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-265, "score" : 882.0, "model-ac" : "3nynB02" }, { "signature" : { "accession" : "G3DSA:1.10.510.10", "name" : "Transferase(Phosphotransferase) domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 267, "end" : 478, "hmmStart" : 1, "hmmEnd" : 530, "hmmLength" : 533, "hmmBounds" : "INCOMPLETE", "evalue" : 6.1E-265, "score" : 881.7, "envelopeStart" : 3, "envelopeEnd" : 538, "postProcessed" : true, "location-fragments" : [ { "start" : 267, "end" : 478, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-265, "score" : 882.0, "model-ac" : "3nynB03" }, { "signature" : { "accession" : "PF00069", "name" : "Pkinase", "description" : "Protein kinase domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 188, "end" : 451, "hmmStart" : 3, "hmmEnd" : 264, "hmmLength" : 264, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.3E-63, "score" : 213.5, "envelopeStart" : 186, "envelopeEnd" : 451, "postProcessed" : true, "location-fragments" : [ { "start" : 188, "end" : 451, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-63, "score" : 214.2, "model-ac" : "PF00069" }, { "signature" : { "accession" : "PTHR24355:SF28", "name" : "G PROTEIN-COUPLED RECEPTOR KINASE 2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 574, "hmmStart" : 1, "hmmEnd" : 564, "hmmLength" : 572, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 582, "location-fragments" : [ { "start" : 1, "end" : 574, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-299, "familyName" : "G PROTEIN-COUPLED RECEPTOR KINASE 2", "score" : 995.5, "model-ac" : "PTHR24355:SF28" }, { "signature" : { "accession" : "SM00133", "name" : "pkinase_C_6", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000961", "name" : "AGC-kinase_C", "description" : "AGC-kinase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein serine/threonine kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004674" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 452, "end" : 531, "hmmStart" : 1, "hmmEnd" : 79, "hmmLength" : 79, "hmmBounds" : "COMPLETE", "evalue" : 8.9E-9, "score" : 45.2, "location-fragments" : [ { "start" : 452, "end" : 531, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.9E-9, "score" : 45.2, "model-ac" : "SM00133" }, { "signature" : { "accession" : "PR00717", "name" : "GPCRKINASE", "description" : "GPCR kinase signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000239", "name" : "GPCR_kinase", "description" : "GPCR kinase", "type" : "FAMILY", "goXRefs" : [ { "name" : "signal transduction", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007165" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "G protein-coupled receptor kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004703" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 466, "end" : 483, "pvalue" : 2.07E-12, "score" : 72.75, "motifNumber" : 3, "location-fragments" : [ { "start" : 466, "end" : 483, "dc-status" : "CONTINUOUS" } ] }, { "start" : 225, "end" : 243, "pvalue" : 9.79E-11, "score" : 59.77, "motifNumber" : 2, "location-fragments" : [ { "start" : 225, "end" : 243, "dc-status" : "CONTINUOUS" } ] }, { "start" : 489, "end" : 502, "pvalue" : 3.99E-7, "score" : 57.99, "motifNumber" : 4, "location-fragments" : [ { "start" : 489, "end" : 502, "dc-status" : "CONTINUOUS" } ] }, { "start" : 167, "end" : 179, "pvalue" : 4.43E-6, "score" : 66.67, "motifNumber" : 1, "location-fragments" : [ { "start" : 167, "end" : 179, "dc-status" : "CONTINUOUS" } ] }, { "start" : 504, "end" : 521, "pvalue" : 7.53E-9, "score" : 66.27, "motifNumber" : 5, "location-fragments" : [ { "start" : 504, "end" : 521, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-36, "graphscan" : "IIIII", "model-ac" : "PR00717" }, { "signature" : { "accession" : "PS00107", "name" : "PROTEIN_KINASE_ATP", "description" : "Protein kinases ATP-binding region signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017441", "name" : "Protein_kinase_ATP_BS", "description" : "Protein kinase, ATP binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 192, "end" : 224, "level" : "STRONG", "cigarAlignment" : "10M1I1M17I4M", "alignment" : "LGKGGFGEVCaCqvratgkmyackklekkRIKK", "location-fragments" : [ { "start" : 192, "end" : 224, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00107" }, { "signature" : { "accession" : "cd05605", "name" : "STKc_GRK4_like", "description" : "STKc_GRK4_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 185, "end" : 472, "sites" : [ { "description" : "polypeptide substrate binding site", "numLocations" : 16, "siteLocations" : [ { "start" : 270, "end" : 270, "residue" : "D" }, { "start" : 348, "end" : 348, "residue" : "G" }, { "start" : 384, "end" : 384, "residue" : "A" }, { "start" : 316, "end" : 316, "residue" : "E" }, { "start" : 378, "end" : 378, "residue" : "E" }, { "start" : 312, "end" : 312, "residue" : "D" }, { "start" : 346, "end" : 346, "residue" : "R" }, { "start" : 347, "end" : 347, "residue" : "V" }, { "start" : 196, "end" : 196, "residue" : "G" }, { "start" : 314, "end" : 314, "residue" : "K" }, { "start" : 387, "end" : 387, "residue" : "R" }, { "start" : 272, "end" : 272, "residue" : "K" }, { "start" : 333, "end" : 333, "residue" : "L" }, { "start" : 350, "end" : 350, "residue" : "A" }, { "start" : 351, "end" : 351, "residue" : "G" }, { "start" : 349, "end" : 349, "residue" : "T" } ] }, { "description" : "active site", "numLocations" : 31, "siteLocations" : [ { "start" : 270, "end" : 270, "residue" : "D" }, { "start" : 348, "end" : 348, "residue" : "G" }, { "start" : 384, "end" : 384, "residue" : "A" }, { "start" : 329, "end" : 329, "residue" : "S" }, { "start" : 247, "end" : 247, "residue" : "V" }, { "start" : 312, "end" : 312, "residue" : "D" }, { "start" : 213, "end" : 213, "residue" : "A" }, { "start" : 263, "end" : 263, "residue" : "L" }, { "start" : 387, "end" : 387, "residue" : "R" }, { "start" : 351, "end" : 351, "residue" : "G" }, { "start" : 349, "end" : 349, "residue" : "T" }, { "start" : 264, "end" : 264, "residue" : "T" }, { "start" : 194, "end" : 194, "residue" : "K" }, { "start" : 319, "end" : 319, "residue" : "L" }, { "start" : 193, "end" : 193, "residue" : "G" }, { "start" : 215, "end" : 215, "residue" : "K" }, { "start" : 192, "end" : 192, "residue" : "L" }, { "start" : 316, "end" : 316, "residue" : "E" }, { "start" : 378, "end" : 378, "residue" : "E" }, { "start" : 346, "end" : 346, "residue" : "R" }, { "start" : 347, "end" : 347, "residue" : "V" }, { "start" : 266, "end" : 266, "residue" : "M" }, { "start" : 196, "end" : 196, "residue" : "G" }, { "start" : 314, "end" : 314, "residue" : "K" }, { "start" : 317, "end" : 317, "residue" : "N" }, { "start" : 272, "end" : 272, "residue" : "K" }, { "start" : 333, "end" : 333, "residue" : "L" }, { "start" : 350, "end" : 350, "residue" : "A" }, { "start" : 330, "end" : 330, "residue" : "D" }, { "start" : 200, "end" : 200, "residue" : "V" }, { "start" : 195, "end" : 195, "residue" : "G" } ] }, { "description" : "ATP binding site", "numLocations" : 13, "siteLocations" : [ { "start" : 194, "end" : 194, "residue" : "K" }, { "start" : 319, "end" : 319, "residue" : "L" }, { "start" : 193, "end" : 193, "residue" : "G" }, { "start" : 215, "end" : 215, "residue" : "K" }, { "start" : 192, "end" : 192, "residue" : "L" }, { "start" : 213, "end" : 213, "residue" : "A" }, { "start" : 266, "end" : 266, "residue" : "M" }, { "start" : 196, "end" : 196, "residue" : "G" }, { "start" : 330, "end" : 330, "residue" : "D" }, { "start" : 200, "end" : 200, "residue" : "V" }, { "start" : 265, "end" : 265, "residue" : "I" }, { "start" : 195, "end" : 195, "residue" : "G" }, { "start" : 264, "end" : 264, "residue" : "T" } ] }, { "description" : "activation loop (A-loop)", "numLocations" : 23, "siteLocations" : [ { "start" : 344, "end" : 344, "residue" : "Q" }, { "start" : 332, "end" : 332, "residue" : "G" }, { "start" : 348, "end" : 348, "residue" : "G" }, { "start" : 329, "end" : 329, "residue" : "S" }, { "start" : 343, "end" : 343, "residue" : "V" }, { "start" : 342, "end" : 342, "residue" : "M" }, { "start" : 335, "end" : 335, "residue" : "A" }, { "start" : 341, "end" : 341, "residue" : "E" }, { "start" : 337, "end" : 337, "residue" : "I" }, { "start" : 346, "end" : 346, "residue" : "R" }, { "start" : 336, "end" : 336, "residue" : "E" }, { "start" : 347, "end" : 347, "residue" : "V" }, { "start" : 340, "end" : 340, "residue" : "G" }, { "start" : 345, "end" : 345, "residue" : "G" }, { "start" : 333, "end" : 333, "residue" : "L" }, { "start" : 334, "end" : 334, "residue" : "A" }, { "start" : 350, "end" : 350, "residue" : "A" }, { "start" : 351, "end" : 351, "residue" : "G" }, { "start" : 330, "end" : 330, "residue" : "D" }, { "start" : 331, "end" : 331, "residue" : "L" }, { "start" : 339, "end" : 339, "residue" : "E" }, { "start" : 349, "end" : 349, "residue" : "T" }, { "start" : 338, "end" : 338, "residue" : "P" } ] } ], "evalue" : 0.0, "score" : 565.829, "location-fragments" : [ { "start" : 185, "end" : 472, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd05605" }, { "signature" : { "accession" : "G3DSA:3.30.200.20", "name" : "Phosphorylase Kinase; domain 1", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 535, "hmmStart" : 1, "hmmEnd" : 530, "hmmLength" : 255, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.1E-265, "score" : 881.7, "envelopeStart" : 3, "envelopeEnd" : 538, "postProcessed" : true, "location-fragments" : [ { "start" : 3, "end" : 73, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 154, "end" : 265, "dc-status" : "NC_TERMINAL_DISC" }, { "start" : 480, "end" : 535, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 5.1E-265, "score" : 882.0, "model-ac" : "3nynB01" }, { "signature" : { "accession" : "SSF56112", "name" : "Protein kinase-like (PK-like)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011009", "name" : "Kinase-like_dom_sf", "description" : "Protein kinase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 183, "end" : 537, "hmmLength" : 364, "location-fragments" : [ { "start" : 183, "end" : 537, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.93E-78, "model-ac" : "0041927" }, { "signature" : { "accession" : "PF00615", "name" : "RGS", "description" : "Regulator of G protein signaling domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR016137", "name" : "RGS", "description" : "RGS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 53, "end" : 169, "hmmStart" : 2, "hmmEnd" : 117, "hmmLength" : 118, "hmmBounds" : "INCOMPLETE", "evalue" : 8.4E-15, "score" : 55.1, "envelopeStart" : 52, "envelopeEnd" : 170, "postProcessed" : true, "location-fragments" : [ { "start" : 53, "end" : 169, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-15, "score" : 55.1, "model-ac" : "PF00615" }, { "signature" : { "accession" : "PS50132", "name" : "RGS", "description" : "RGS domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR016137", "name" : "RGS", "description" : "RGS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 59, "end" : 171, "score" : 23.07, "alignment" : "------QQPIGRLLFRQFCQEVCPQyhTHNVFLDSVEQYEVESD-ENRNEQARSLFDKHLETNAPEPVEVISSEIIEQCRERLTSG--CRELFTHCSDVVKTFLAGEPFDAFKASMYCNRYL", "location-fragments" : [ { "start" : 59, "end" : 171, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50132" }, { "signature" : { "accession" : "PTHR24355", "name" : "G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 574, "hmmStart" : 1, "hmmEnd" : 564, "hmmLength" : 572, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 582, "location-fragments" : [ { "start" : 1, "end" : 574, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-299, "familyName" : "G PROTEIN-COUPLED RECEPTOR KINASE 2", "score" : 995.5, "model-ac" : "PTHR24355" }, { "signature" : { "accession" : "PS50011", "name" : "PROTEIN_KINASE_DOM", "description" : "Protein kinase domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000719", "name" : "Prot_kinase_dom", "description" : "Protein kinase domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004672" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "protein phosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006468" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 186, "end" : 451, "score" : 39.99, "alignment" : "FRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRkGEAMVLREKQILQKINSKFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGDpgFDIPRARFYAAEVLCGLEHLHYQGLVYMDCKPENILLDDAGHVRISDLGLAAEIPEG-EMVQGRVGTAGYMAPEVI-DNGVYAFSPDWFSFGCLIYEMIEGQAPFRGRkekVKREEVDRRAKEDQ-----EKYSNkFTEEAKSLCKQLLKKSHKVRLGCHSGRHgarevkqHEFF", "location-fragments" : [ { "start" : 186, "end" : 451, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50011" }, { "signature" : { "accession" : "SM00315", "name" : "RGS_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR016137", "name" : "RGS", "description" : "RGS domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 52, "end" : 171, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 3.4E-21, "score" : 86.4, "location-fragments" : [ { "start" : 52, "end" : 171, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-21, "score" : 86.4, "model-ac" : "SM00315" } ], "xref" : [ { "name" : "XP_018909836.1 PREDICTED: G protein-coupled receptor kinase 2 [Bemisia tabaci]", "id" : "XP_018909836.1" } ] },{ "sequence" : "MINYTDEHVAIIRKWLEEEPNLPGDFEEAMIKRFLHCCSNDIERTKKVMKLFFNCRLNFKEFFGNVDFHSDQVQRILTAIDTLPLPRRTKEGYQVYVTRLRDTNPDNFNLADYSKMFFMMHDTRMRTEDIPAGDVPILDMEGFSFKHLTKLIFNFGTLKKYLLYNQEAHPVKLMQVHIVNTNGLLHKAFSLVKPLLNPHVKDMLHFHTPGSDTIDEFVPKDLLPKEYGGNTGSVDELKEIWVKKIKEQAEWLAIEDRWKEIPPEKLNKQIDLEQSFSKIEFD", "md5" : "7531f5f1ca2c099d15067a3eec0aaf62", "matches" : [ { "signature" : { "accession" : "PTHR10174", "name" : "RETINALDEHYDE BINDING PROTEIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 269, "hmmStart" : 21, "hmmEnd" : 282, "hmmLength" : 298, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 280, "location-fragments" : [ { "start" : 7, "end" : 269, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.2E-81, "familyName" : "", "score" : 273.8, "model-ac" : "PTHR10174" }, { "signature" : { "accession" : "SSF46938", "name" : "CRAL/TRIO N-terminal domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036273", "name" : "CRAL/TRIO_N_dom_sf", "description" : "CRAL/TRIO, N-terminal domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 68, "hmmLength" : 82, "location-fragments" : [ { "start" : 7, "end" : 68, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.5E-10, "model-ac" : "0048578" }, { "signature" : { "accession" : "SSF52087", "name" : "CRAL/TRIO domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036865", "name" : "CRAL-TRIO_dom_sf", "description" : "CRAL-TRIO lipid binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 75, "end" : 252, "hmmLength" : 185, "location-fragments" : [ { "start" : 75, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.62E-36, "model-ac" : "0043136" }, { "signature" : { "accession" : "PR00180", "name" : "CRETINALDHBP", "description" : "Cellular retinaldehyde-binding protein signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : null }, "locations" : [ { "start" : 189, "end" : 208, "pvalue" : 4.6E-6, "score" : 32.5, "motifNumber" : 4, "location-fragments" : [ { "start" : 189, "end" : 208, "dc-status" : "CONTINUOUS" } ] }, { "start" : 156, "end" : 177, "pvalue" : 5.81E-4, "score" : 22.73, "motifNumber" : 3, "location-fragments" : [ { "start" : 156, "end" : 177, "dc-status" : "CONTINUOUS" } ] }, { "start" : 30, "end" : 52, "pvalue" : 0.0111, "score" : 18.48, "motifNumber" : 1, "location-fragments" : [ { "start" : 30, "end" : 52, "dc-status" : "CONTINUOUS" } ] }, { "start" : 221, "end" : 230, "pvalue" : 6.87E-6, "score" : 60.0, "motifNumber" : 5, "location-fragments" : [ { "start" : 221, "end" : 230, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-10, "graphscan" : "i.iII", "model-ac" : "PR00180" }, { "signature" : { "accession" : "SM00516", "name" : "sec14_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001251", "name" : "CRAL-TRIO_dom", "description" : "CRAL-TRIO lipid binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 75, "end" : 232, "hmmStart" : 1, "hmmEnd" : 184, "hmmLength" : 184, "hmmBounds" : "COMPLETE", "evalue" : 0.009, "score" : 24.0, "location-fragments" : [ { "start" : 75, "end" : 232, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.009, "score" : 24.0, "model-ac" : "SM00516" }, { "signature" : { "accession" : "PTHR10174:SF222", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 269, "hmmStart" : 21, "hmmEnd" : 282, "hmmLength" : 298, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 280, "location-fragments" : [ { "start" : 7, "end" : 269, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.2E-81, "familyName" : "", "score" : 273.8, "model-ac" : "PTHR10174:SF222" }, { "signature" : { "accession" : "PS50191", "name" : "CRAL_TRIO", "description" : "CRAL-TRIO lipid binding domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001251", "name" : "CRAL-TRIO_dom", "description" : "CRAL-TRIO lipid binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 70, "end" : 235, "score" : 14.058, "alignment" : "SDQVQRILTAIDTLPLprrTKEGYQVYVTRLRDTNP-DNFNLADYSKMFFMMHDTRMRTEDIPAGD-----VPILDMEGFSFKHLTkliFNFGTLKKYLLYNQEAHPVKLMQVHIVNTNGLLHKAFSLVKPLLNPHVKDMLHFHTP-GSDTIDEFVPKDLLPKEYGGNTGSVD", "location-fragments" : [ { "start" : 70, "end" : 235, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50191" }, { "signature" : { "accession" : "PF00650", "name" : "CRAL_TRIO", "description" : "CRAL/TRIO domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001251", "name" : "CRAL-TRIO_dom", "description" : "CRAL-TRIO lipid binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 85, "end" : 230, "hmmStart" : 11, "hmmEnd" : 159, "hmmLength" : 159, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 8.0E-18, "score" : 64.7, "envelopeStart" : 82, "envelopeEnd" : 230, "postProcessed" : true, "location-fragments" : [ { "start" : 85, "end" : 230, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-18, "score" : 65.6, "model-ac" : "PF00650" }, { "signature" : { "accession" : "G3DSA:3.40.525.10", "name" : "Phosphatidylinositol Transfer Protein Sec14p", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036865", "name" : "CRAL-TRIO_dom_sf", "description" : "CRAL-TRIO lipid binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 64, "end" : 256, "hmmStart" : 7, "hmmEnd" : 191, "hmmLength" : 198, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-44, "score" : 153.1, "envelopeStart" : 64, "envelopeEnd" : 256, "postProcessed" : true, "location-fragments" : [ { "start" : 64, "end" : 256, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-44, "score" : 153.8, "model-ac" : "1oizA02" }, { "signature" : { "accession" : "cd00170", "name" : "SEC14", "description" : "SEC14", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR001251", "name" : "CRAL-TRIO_dom", "description" : "CRAL-TRIO lipid binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 85, "end" : 230, "sites" : [ { "description" : "phospholipid binding pocket", "numLocations" : 16, "siteLocations" : [ { "start" : 138, "end" : 138, "residue" : "L" }, { "start" : 94, "end" : 94, "residue" : "Q" }, { "start" : 178, "end" : 178, "residue" : "I" }, { "start" : 158, "end" : 158, "residue" : "L" }, { "start" : 176, "end" : 176, "residue" : "V" }, { "start" : 192, "end" : 192, "residue" : "V" }, { "start" : 185, "end" : 185, "residue" : "L" }, { "start" : 140, "end" : 140, "residue" : "M" }, { "start" : 170, "end" : 170, "residue" : "P" }, { "start" : 162, "end" : 162, "residue" : "L" }, { "start" : 166, "end" : 166, "residue" : "Q" }, { "start" : 173, "end" : 173, "residue" : "L" }, { "start" : 96, "end" : 96, "residue" : "Y" }, { "start" : 124, "end" : 124, "residue" : "R" }, { "start" : 98, "end" : 98, "residue" : "T" }, { "start" : 204, "end" : 204, "residue" : "L" } ] }, { "description" : "salt bridge", "numLocations" : 2, "siteLocations" : [ { "start" : 203, "end" : 203, "residue" : "M" }, { "start" : 171, "end" : 171, "residue" : "V" } ] } ], "evalue" : 6.47219E-23, "score" : 90.137, "location-fragments" : [ { "start" : 85, "end" : 230, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00170" } ], "xref" : [ { "name" : "XP_018910064.1 PREDICTED: alpha-tocopherol transfer protein-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910064.1" } ] },{ "sequence" : "MTGGEYLGLTMPETSLVNGYQGNGHMEPEIPDGENFLFTSESVGEGHPDKMCDQISDAILDAHLKEDPDAKVACETVTKTGMVLLCGEITSKANVDYQKVVRDTIKHIGYDDSSKGFDYETCNVLVAMDAQSPNIAEGVHVNRAEDMIGAGDQGLMFGYATDETEECMPLTVVLAHKLNERIADMRRSGVFWWARPDSKTQVTCEYCFQHGACVPLRVHTVVVSIQHSEKITLEELRTEIMNKVIKEVIPTKYLDDKTMFHINPCGQFVLGGPRCDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKSGLCRRCLVQVSYAIGVAEPISITLFEYGTAKKTQKELLEIVKRNFDLRPGKIVRDLNLRNPIYQKTSTYGHFGRDIFPWEQPKLLV", "md5" : "48e603f5386ed57ada410d2f7753f156", "matches" : [ { "signature" : { "accession" : "PF02773", "name" : "S-AdoMet_synt_C", "description" : "S-adenosylmethionine synthetase, C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022630", "name" : "S-AdoMet_synt_C", "description" : "S-adenosylmethionine synthetase, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" } ], "pathwayXRefs" : [ { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 270, "end" : 407, "hmmStart" : 1, "hmmEnd" : 138, "hmmLength" : 138, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-66, "score" : 221.7, "envelopeStart" : 270, "envelopeEnd" : 407, "postProcessed" : true, "location-fragments" : [ { "start" : 270, "end" : 407, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-66, "score" : 222.9, "model-ac" : "PF02773" }, { "signature" : { "accession" : "SSF55973", "name" : "S-adenosylmethionine synthetase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR022636", "name" : "S-AdoMet_synthetase_sfam", "description" : "S-adenosylmethionine synthetase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" } ], "pathwayXRefs" : [ { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 146, "end" : 269, "hmmLength" : 126, "location-fragments" : [ { "start" : 146, "end" : 269, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.93E-50, "model-ac" : "0054442" }, { "signature" : { "accession" : "PF00438", "name" : "S-AdoMet_synt_N", "description" : "S-adenosylmethionine synthetase, N-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022628", "name" : "S-AdoMet_synt_N", "description" : "S-adenosylmethionine synthetase, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" } ] } }, "locations" : [ { "start" : 35, "end" : 133, "hmmStart" : 1, "hmmEnd" : 99, "hmmLength" : 99, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-43, "score" : 147.7, "envelopeStart" : 35, "envelopeEnd" : 133, "postProcessed" : true, "location-fragments" : [ { "start" : 35, "end" : 133, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-45, "score" : 153.5, "model-ac" : "PF00438" }, { "signature" : { "accession" : "PF02772", "name" : "S-AdoMet_synt_M", "description" : "S-adenosylmethionine synthetase, central domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022629", "name" : "S-AdoMet_synt_central", "description" : "S-adenosylmethionine synthetase, central domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" } ] } }, "locations" : [ { "start" : 148, "end" : 268, "hmmStart" : 2, "hmmEnd" : 120, "hmmLength" : 120, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 8.0E-45, "score" : 151.9, "envelopeStart" : 147, "envelopeEnd" : 268, "postProcessed" : true, "location-fragments" : [ { "start" : 148, "end" : 268, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-45, "score" : 152.8, "model-ac" : "PF02772" }, { "signature" : { "accession" : "TIGR01034", "name" : "TIGR01034", "description" : "metK: methionine adenosyltransferase", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR002133", "name" : "S-AdoMet_synthetase", "description" : "S-adenosylmethionine synthetase", "type" : "FAMILY", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 37, "end" : 410, "hmmStart" : 1, "hmmEnd" : 369, "hmmLength" : 377, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.0E-178, "score" : 592.0, "envelopeStart" : 37, "envelopeEnd" : 412, "postProcessed" : false, "location-fragments" : [ { "start" : 37, "end" : 410, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.8E-179, "score" : 592.2, "model-ac" : "TIGR01034" }, { "signature" : { "accession" : "cd18079", "name" : "S-AdoMet_synt", "description" : "S-AdoMet_synt", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 37, "end" : 409, "sites" : [ { "description" : "ATP binding site", "numLocations" : 6, "siteLocations" : [ { "start" : 48, "end" : 48, "residue" : "P" }, { "start" : 41, "end" : 41, "residue" : "E" }, { "start" : 199, "end" : 199, "residue" : "K" }, { "start" : 47, "end" : 47, "residue" : "H" }, { "start" : 283, "end" : 283, "residue" : "K" }, { "start" : 197, "end" : 197, "residue" : "D" } ] }, { "description" : "active site", "numLocations" : 28, "siteLocations" : [ { "start" : 48, "end" : 48, "residue" : "P" }, { "start" : 299, "end" : 299, "residue" : "A" }, { "start" : 131, "end" : 131, "residue" : "Q" }, { "start" : 199, "end" : 199, "residue" : "K" }, { "start" : 47, "end" : 47, "residue" : "H" }, { "start" : 270, "end" : 270, "residue" : "L" }, { "start" : 283, "end" : 283, "residue" : "K" }, { "start" : 152, "end" : 152, "residue" : "D" }, { "start" : 297, "end" : 297, "residue" : "G" }, { "start" : 298, "end" : 298, "residue" : "G" }, { "start" : 49, "end" : 49, "residue" : "D" }, { "start" : 268, "end" : 268, "residue" : "F" }, { "start" : 265, "end" : 265, "residue" : "C" }, { "start" : 307, "end" : 307, "residue" : "K" }, { "start" : 197, "end" : 197, "residue" : "D" }, { "start" : 224, "end" : 224, "residue" : "S" }, { "start" : 88, "end" : 88, "residue" : "E" }, { "start" : 135, "end" : 135, "residue" : "I" }, { "start" : 276, "end" : 276, "residue" : "D" }, { "start" : 151, "end" : 151, "residue" : "G" }, { "start" : 282, "end" : 282, "residue" : "R" }, { "start" : 41, "end" : 41, "residue" : "E" }, { "start" : 267, "end" : 267, "residue" : "Q" }, { "start" : 303, "end" : 303, "residue" : "K" }, { "start" : 340, "end" : 340, "residue" : "I" }, { "start" : 73, "end" : 73, "residue" : "A" }, { "start" : 134, "end" : 134, "residue" : "N" }, { "start" : 309, "end" : 309, "residue" : "D" } ] }, { "description" : "homodimer interface", "numLocations" : 50, "siteLocations" : [ { "start" : 199, "end" : 199, "residue" : "K" }, { "start" : 37, "end" : 37, "residue" : "L" }, { "start" : 220, "end" : 220, "residue" : "T" }, { "start" : 157, "end" : 157, "residue" : "F" }, { "start" : 293, "end" : 293, "residue" : "G" }, { "start" : 152, "end" : 152, "residue" : "D" }, { "start" : 297, "end" : 297, "residue" : "G" }, { "start" : 346, "end" : 346, "residue" : "I" }, { "start" : 39, "end" : 39, "residue" : "T" }, { "start" : 261, "end" : 261, "residue" : "H" }, { "start" : 335, "end" : 335, "residue" : "Q" }, { "start" : 77, "end" : 77, "residue" : "V" }, { "start" : 203, "end" : 203, "residue" : "T" }, { "start" : 276, "end" : 276, "residue" : "D" }, { "start" : 285, "end" : 285, "residue" : "I" }, { "start" : 201, "end" : 201, "residue" : "Q" }, { "start" : 294, "end" : 294, "residue" : "A" }, { "start" : 84, "end" : 84, "residue" : "L" }, { "start" : 282, "end" : 282, "residue" : "R" }, { "start" : 347, "end" : 347, "residue" : "S" }, { "start" : 41, "end" : 41, "residue" : "E" }, { "start" : 38, "end" : 38, "residue" : "F" }, { "start" : 303, "end" : 303, "residue" : "K" }, { "start" : 340, "end" : 340, "residue" : "I" }, { "start" : 154, "end" : 154, "residue" : "G" }, { "start" : 280, "end" : 280, "residue" : "T" }, { "start" : 291, "end" : 291, "residue" : "G" }, { "start" : 299, "end" : 299, "residue" : "A" }, { "start" : 153, "end" : 153, "residue" : "Q" }, { "start" : 75, "end" : 75, "residue" : "E" }, { "start" : 277, "end" : 277, "residue" : "A" }, { "start" : 264, "end" : 264, "residue" : "P" }, { "start" : 275, "end" : 275, "residue" : "C" }, { "start" : 338, "end" : 338, "residue" : "Y" }, { "start" : 295, "end" : 295, "residue" : "H" }, { "start" : 296, "end" : 296, "residue" : "G" }, { "start" : 155, "end" : 155, "residue" : "L" }, { "start" : 349, "end" : 349, "residue" : "T" }, { "start" : 88, "end" : 88, "residue" : "E" }, { "start" : 86, "end" : 86, "residue" : "C" }, { "start" : 292, "end" : 292, "residue" : "W" }, { "start" : 290, "end" : 290, "residue" : "G" }, { "start" : 87, "end" : 87, "residue" : "G" }, { "start" : 341, "end" : 341, "residue" : "G" }, { "start" : 222, "end" : 222, "residue" : "V" }, { "start" : 339, "end" : 339, "residue" : "A" }, { "start" : 279, "end" : 279, "residue" : "L" }, { "start" : 79, "end" : 79, "residue" : "K" }, { "start" : 281, "end" : 281, "residue" : "G" }, { "start" : 337, "end" : 337, "residue" : "S" } ] } ], "evalue" : 0.0, "score" : 679.511, "location-fragments" : [ { "start" : 37, "end" : 409, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18079" }, { "signature" : { "accession" : "PIRSF000497", "name" : "MAT", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR002133", "name" : "S-AdoMet_synthetase", "description" : "S-adenosylmethionine synthetase", "type" : "FAMILY", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 31, "end" : 412, "hmmStart" : 34, "hmmEnd" : 410, "hmmLength" : 389, "hmmBounds" : "INCOMPLETE", "evalue" : 1.1E-162, "score" : 537.1, "envelopeStart" : 31, "envelopeEnd" : 412, "postProcessed" : false, "location-fragments" : [ { "start" : 31, "end" : 412, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.2E-163, "score" : 537.3, "model-ac" : "PIRSF000497" }, { "signature" : { "accession" : "PS00377", "name" : "ADOMET_SYNTHASE_2", "description" : "S-adenosylmethionine synthase signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR022631", "name" : "ADOMET_SYNTHASE_CS", "description" : "S-adenosylmethionine synthetase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" } ] } }, "locations" : [ { "start" : 296, "end" : 304, "level" : "STRONG", "cigarAlignment" : "6M1I2M", "alignment" : "GGGAFSgKD", "location-fragments" : [ { "start" : 296, "end" : 304, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00377" }, { "signature" : { "accession" : "PTHR11964", "name" : "S-ADENOSYLMETHIONINE SYNTHETASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR002133", "name" : "S-AdoMet_synthetase", "description" : "S-adenosylmethionine synthetase", "type" : "FAMILY", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 26, "end" : 411, "hmmStart" : 9, "hmmEnd" : 394, "hmmLength" : 396, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 18, "envelopeEnd" : 412, "location-fragments" : [ { "start" : 26, "end" : 411, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-219, "familyName" : "S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1", "score" : 729.3, "model-ac" : "PTHR11964" }, { "signature" : { "accession" : "PTHR11964:SF11", "name" : "S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 26, "end" : 411, "hmmStart" : 9, "hmmEnd" : 394, "hmmLength" : 396, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 18, "envelopeEnd" : 412, "location-fragments" : [ { "start" : 26, "end" : 411, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-219, "familyName" : "S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1", "score" : 729.3, "model-ac" : "PTHR11964:SF11" }, { "signature" : { "accession" : "PS00376", "name" : "ADOMET_SYNTHASE_1", "description" : "S-adenosylmethionine synthase signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR022631", "name" : "ADOMET_SYNTHASE_CS", "description" : "S-adenosylmethionine synthetase, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" } ] } }, "locations" : [ { "start" : 149, "end" : 159, "level" : "STRONG", "cigarAlignment" : "6M3I2M", "alignment" : "GAGDQGlmfGY", "location-fragments" : [ { "start" : 149, "end" : 159, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00376" }, { "signature" : { "accession" : "SSF55973", "name" : "S-adenosylmethionine synthetase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR022636", "name" : "S-AdoMet_synthetase_sfam", "description" : "S-adenosylmethionine synthetase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" } ], "pathwayXRefs" : [ { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 35, "end" : 142, "hmmLength" : 110, "location-fragments" : [ { "start" : 35, "end" : 142, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.33E-47, "model-ac" : "0054441" }, { "signature" : { "accession" : "MF_00086", "name" : "S_AdoMet_synth1", "description" : "S-adenosylmethionine synthase [metK].", "signatureLibraryRelease" : { "library" : "HAMAP", "version" : "2020_01" }, "entry" : { "accession" : "IPR002133", "name" : "S-AdoMet_synthetase", "description" : "S-adenosylmethionine synthetase", "type" : "FAMILY", "goXRefs" : [ { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" }, { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 34, "end" : 412, "score" : 49.917, "alignment" : "ENFLFTSESVGEGHPDKMCDQISDAILDAHLKEDPDAKVACETVTKTGMVLLCGEITSKANVDYQKVVRDTIKHIGYDDSSKGFDYETCNVLVAMDAQSPNIAEGVHVNRAeDMIGAGDQGLMFGYATDETEECMPLTVVLAHKLNERIADMRRSGVFWWARPDSKTQVTCEYCFQHgacvPLRVHTVVVSIQHSEKITLEELRTEIMNKVIKEVIPTKYLDD-KTMFHINPCGQFVLGGPRCDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKSGLCRRCLVQVSYAIGVAEPISITLFEYGTAKKTQKELLEIVKRNFDLRPGKIVRDLNLRNPIYQKTSTYGHFGRDIFPWEQP------KLLV", "location-fragments" : [ { "start" : 34, "end" : 412, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "MF_00086" }, { "signature" : { "accession" : "G3DSA:3.30.300.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 43, "end" : 309, "hmmStart" : 1, "hmmEnd" : 368, "hmmLength" : 141, "hmmBounds" : "INCOMPLETE", "evalue" : 2.3E-173, "score" : 578.3, "envelopeStart" : 37, "envelopeEnd" : 406, "postProcessed" : true, "location-fragments" : [ { "start" : 273, "end" : 309, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 43, "end" : 146, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.1E-173, "score" : 578.5, "model-ac" : "5a1iA02" }, { "signature" : { "accession" : "SSF55973", "name" : "S-adenosylmethionine synthetase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR022636", "name" : "S-AdoMet_synthetase_sfam", "description" : "S-adenosylmethionine synthetase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "S-adenosylmethionine biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006556" }, { "name" : "methionine adenosyltransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004478" } ], "pathwayXRefs" : [ { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+2.5.1.6" }, { "name" : "2'-deoxymugineic acid phytosiderophore biosynthesis", "databaseName" : "MetaCyc", "id" : "PWY-5912" }, { "name" : "Methylation", "databaseName" : "Reactome", "id" : "R-HSA-156581" }, { "name" : "S-adenosyl-L-methionine cycle II", "databaseName" : "MetaCyc", "id" : "PWY-5041" } ] } }, "locations" : [ { "start" : 270, "end" : 410, "hmmLength" : 152, "location-fragments" : [ { "start" : 270, "end" : 410, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.02E-64, "model-ac" : "0041133" }, { "signature" : { "accession" : "G3DSA:3.30.300.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 147, "end" : 406, "hmmStart" : 1, "hmmEnd" : 368, "hmmLength" : 128, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.3E-173, "score" : 578.3, "envelopeStart" : 37, "envelopeEnd" : 406, "postProcessed" : true, "location-fragments" : [ { "start" : 310, "end" : 406, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 147, "end" : 169, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 2.1E-173, "score" : 578.5, "model-ac" : "5a1iA03" }, { "signature" : { "accession" : "G3DSA:3.30.300.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 37, "end" : 272, "hmmStart" : 1, "hmmEnd" : 368, "hmmLength" : 125, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.3E-173, "score" : 578.3, "envelopeStart" : 37, "envelopeEnd" : 406, "postProcessed" : true, "location-fragments" : [ { "start" : 37, "end" : 42, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 170, "end" : 272, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 2.1E-173, "score" : 578.5, "model-ac" : "5a1iA01" } ], "xref" : [ { "name" : "XP_018910507.1 PREDICTED: S-adenosylmethionine synthase isoform X1 [Bemisia tabaci]", "id" : "XP_018910507.1" } ] },{ "sequence" : "MMAAAQECGNQYSLSKKEDTSMRRSGGRGYPKLRGRGNITRGRSRSYSHHGQASYFSPNSSSFRFQNSFSSPDSDPVGTARDRLTNFDHSASNSNGFKSQNLVFSPDIDSVGAAHNRLTNSDRFATNSKGFKSQNRFFSPDSDVEDTAYSRFTNSDRSSTNSPSFRFQNGCNKKLDSSPKKFKYFPDPYNAGSNTNSDEKPNFPFKNQKFFPEPRNVCWGGDADRNLNNKKHRNFIKATGENSSTTTNANRVTNSSPTSDETPSCSCNDVSLSDLLAALNDKFSEEMNMIESLDSEVTNTWCYIKEIADVGIEDMDLSGFQKQSNFAEENNFAQPSVSRERTASDEIEVLWQEFESLESKLFQKRNGEKNSNLKSKPAKNSQDEQEILKSKPTKNSQDEQEIEGLKTTIGILTTQLQKDKNNFNTKLDKIQNQLEGRIEAINATLKKEREINKELQEKMKRGYEDMIQTIKAEYTTKLDAHKAEKEELAEQLNLQLNLTESLAKEAEDLRTQMESNKRLTLQTIKETLKDNCECSICLGICTKAVITSCGHTFCKRCLEGWQAWRNENQMCPNCRAVCTSSNIYFFNELITQLQLKFPNMDWIPSS", "md5" : "f8eceab5324b65347a246c05e193b08d", "matches" : [ { "signature" : { "accession" : "G3DSA:3.30.40.10", "name" : "Zinc/RING finger domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013083", "name" : "Znf_RING/FYVE/PHD", "description" : "Zinc finger, RING/FYVE/PHD-type", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 503, "end" : 603, "hmmStart" : 11, "hmmEnd" : 99, "hmmLength" : 130, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-17, "score" : 64.5, "envelopeStart" : 503, "envelopeEnd" : 603, "postProcessed" : true, "location-fragments" : [ { "start" : 503, "end" : 603, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-17, "score" : 64.5, "model-ac" : "5dinA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 230, "end" : 262, "location-fragments" : [ { "start" : 230, "end" : 262, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 471, "end" : 516, "location-fragments" : [ { "start" : 471, "end" : 516, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 365, "end" : 402, "location-fragments" : [ { "start" : 365, "end" : 402, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF13445", "name" : "zf-RING_UBOX", "description" : "RING-type zinc-finger", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR027370", "name" : "Znf-RING_LisH", "description" : "RING-type zinc-finger, LisH dimerisation motif", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 534, "end" : 572, "hmmStart" : 1, "hmmEnd" : 40, "hmmLength" : 40, "hmmBounds" : "COMPLETE", "evalue" : 4.2E-7, "score" : 29.9, "envelopeStart" : 534, "envelopeEnd" : 572, "postProcessed" : true, "location-fragments" : [ { "start" : 534, "end" : 572, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-7, "score" : 31.0, "model-ac" : "PF13445" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 276, "end" : 296, "location-fragments" : [ { "start" : 276, "end" : 296, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR23327", "name" : "RING FINGER PROTEIN 127", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 399, "end" : 579, "hmmStart" : 56, "hmmEnd" : 196, "hmmLength" : 446, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 234, "envelopeEnd" : 594, "location-fragments" : [ { "start" : 399, "end" : 579, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-16, "familyName" : "RING FINGER PROTEIN 127", "score" : 62.3, "model-ac" : "PTHR23327" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 438, "end" : 465, "location-fragments" : [ { "start" : 438, "end" : 465, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 41, "end" : 75, "location-fragments" : [ { "start" : 41, "end" : 75, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57850", "name" : "RING/U-box", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 517, "end" : 580, "hmmLength" : 114, "location-fragments" : [ { "start" : 517, "end" : 580, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.83E-15, "model-ac" : "0050087" }, { "signature" : { "accession" : "SM00184", "name" : "ring_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 534, "end" : 574, "hmmStart" : 1, "hmmEnd" : 23, "hmmLength" : 23, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-7, "score" : 39.5, "location-fragments" : [ { "start" : 534, "end" : 574, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-7, "score" : 39.5, "model-ac" : "SM00184" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 87, "location-fragments" : [ { "start" : 1, "end" : 87, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 379, "end" : 401, "location-fragments" : [ { "start" : 379, "end" : 401, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 238, "end" : 262, "location-fragments" : [ { "start" : 238, "end" : 262, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd16449", "name" : "RING-HC", "description" : "RING-HC", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 534, "end" : 574, "sites" : [ { "description" : "Zn binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 534, "end" : 534, "residue" : "C" }, { "start" : 574, "end" : 574, "residue" : "C" }, { "start" : 571, "end" : 571, "residue" : "C" }, { "start" : 551, "end" : 551, "residue" : "H" }, { "start" : 537, "end" : 537, "residue" : "C" }, { "start" : 554, "end" : 554, "residue" : "C" }, { "start" : 549, "end" : 549, "residue" : "C" }, { "start" : 557, "end" : 557, "residue" : "C" } ] } ], "evalue" : 1.77051E-12, "score" : 59.7885, "location-fragments" : [ { "start" : 534, "end" : 574, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd16449" }, { "signature" : { "accession" : "PS00518", "name" : "ZF_RING_1", "description" : "Zinc finger RING-type signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017907", "name" : "Znf_RING_CS", "description" : "Zinc finger, RING-type, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 549, "end" : 558, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I2M2I2M", "alignment" : "CgHtFCkrCL", "location-fragments" : [ { "start" : 549, "end" : 558, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00518" }, { "signature" : { "accession" : "cd06503", "name" : "ATP-synt_Fo_b", "description" : "ATP-synt_Fo_b", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 429, "end" : 526, "sites" : [ ], "evalue" : 6.6309E-4, "score" : 38.1875, "location-fragments" : [ { "start" : 429, "end" : 526, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd06503" }, { "signature" : { "accession" : "PS50089", "name" : "ZF_RING_2", "description" : "Zinc finger RING-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001841", "name" : "Znf_RING", "description" : "Zinc finger, RING-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 534, "end" : 575, "score" : 13.065, "alignment" : "CSICLGICTKA--VITSCGHTFCKRCLEGWqAWRNENQMCPNCR", "location-fragments" : [ { "start" : 534, "end" : 575, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50089" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 413, "end" : 433, "location-fragments" : [ { "start" : 413, "end" : 433, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" } ], "xref" : [ { "name" : "XP_018910236.1 PREDICTED: E3 ubiquitin-protein ligase BRE1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018910236.1" } ] },{ "sequence" : "MATSMSSTKSSVQVSDASFSTNQPRYNEENLIAFLRKAGQTVLKVLDEEDPSLKCLSEPITEEADVEFKQICSLEGHVSVLVSSISWSCDEKLIALSYRHHHDNWCHHAGTIHLFKYEESSCQECPAKQPIHTLTLKNCVTSVSFHPNDRTVLAAGTVTGDVYLWSVKKSIVKSEIFSGHHSDCISQISWISNPSNSKLMLASASKDSFIIVWDVSLQSNSIKPKLRFFFEDESHPSVEPGIRCFSFAPLQPDCFVVALMNGNLLKCSIVAARPIPQVKDKKYSMQNAVVSAYKKCSSSPVISIDFQQTKNNMFVAVATDQKCFVYSLTEMEPLRVIISDENIIGASWYQPDTQYFMTWGESVATFYNVKRENFRLNFKPFQSKVDSTLISAVCFNPQMQNRAAFGAESGKTVVWKIPTRVNKDEDALS", "md5" : "7395985f515a8a6ff89b56904ad77e26", "matches" : [ { "signature" : { "accession" : "PS50294", "name" : "WD_REPEATS_REGION", "description" : "Trp-Asp (WD) repeats circular profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR017986", "name" : "WD40_repeat_dom", "description" : "WD40-repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 133, "end" : 223, "score" : 11.471, "alignment" : "TLTLKNCVTSVSFHPNdRTVLAAGTVTGDVYLWSVKKSIVKSEifSGHHSDCISQISWISNpsnsKLMLASASKDSFIIVWDVSLQSNSIK", "location-fragments" : [ { "start" : 133, "end" : 223, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50294" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 225, "hmmStart" : 237, "hmmEnd" : 379, "hmmLength" : 457, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-19, "score" : 71.7, "envelopeStart" : 7, "envelopeEnd" : 225, "postProcessed" : true, "location-fragments" : [ { "start" : 7, "end" : 225, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-27, "score" : 97.5, "model-ac" : "4zoyA00" }, { "signature" : { "accession" : "SSF50978", "name" : "WD40 repeat-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036322", "name" : "WD40_repeat_dom_sf", "description" : "WD40-repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 68, "end" : 415, "hmmLength" : 340, "location-fragments" : [ { "start" : 68, "end" : 415, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.81E-34, "model-ac" : "0049784" }, { "signature" : { "accession" : "PF00400", "name" : "WD40", "description" : "WD domain, G-beta repeat", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 176, "end" : 214, "hmmStart" : 6, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 0.043, "score" : 14.7, "envelopeStart" : 172, "envelopeEnd" : 214, "postProcessed" : true, "location-fragments" : [ { "start" : 176, "end" : 214, "dc-status" : "CONTINUOUS" } ] }, { "start" : 129, "end" : 166, "hmmStart" : 2, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 0.05, "score" : 14.5, "envelopeStart" : 128, "envelopeEnd" : 166, "postProcessed" : true, "location-fragments" : [ { "start" : 129, "end" : 166, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.2E-7, "score" : 29.6, "model-ac" : "PF00400" }, { "signature" : { "accession" : "PS00678", "name" : "WD_REPEATS_1", "description" : "Trp-Asp (WD) repeats signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019775", "name" : "WD40_repeat_CS", "description" : "WD40 repeat, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 201, "end" : 215, "level" : "STRONG", "cigarAlignment" : "4M2I1M1I7M", "alignment" : "LASAskDsFIIVWDV", "location-fragments" : [ { "start" : 201, "end" : 215, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00678" }, { "signature" : { "accession" : "PTHR12442:SF26", "name" : "WD REPEAT-CONTAINING PROTEIN 34", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 425, "hmmStart" : 82, "hmmEnd" : 484, "hmmLength" : 496, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 429, "location-fragments" : [ { "start" : 12, "end" : 425, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-46, "familyName" : "WD REPEAT-CONTAINING PROTEIN 34", "score" : 161.9, "model-ac" : "PTHR12442:SF26" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 241, "end" : 423, "hmmStart" : 121, "hmmEnd" : 283, "hmmLength" : 401, "hmmBounds" : "COMPLETE", "evalue" : 3.7E-8, "score" : 34.8, "envelopeStart" : 241, "envelopeEnd" : 423, "postProcessed" : true, "location-fragments" : [ { "start" : 241, "end" : 423, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-31, "score" : 111.0, "model-ac" : "4pswB00" }, { "signature" : { "accession" : "SM00320", "name" : "WD40_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 377, "end" : 416, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 110.0, "score" : 4.2, "location-fragments" : [ { "start" : 377, "end" : 416, "dc-status" : "CONTINUOUS" } ] }, { "start" : 286, "end" : 327, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 7.4, "score" : 11.5, "location-fragments" : [ { "start" : 286, "end" : 327, "dc-status" : "CONTINUOUS" } ] }, { "start" : 127, "end" : 166, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 0.0013, "score" : 28.0, "location-fragments" : [ { "start" : 127, "end" : 166, "dc-status" : "CONTINUOUS" } ] }, { "start" : 67, "end" : 116, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 310.0, "score" : 1.2, "location-fragments" : [ { "start" : 67, "end" : 116, "dc-status" : "CONTINUOUS" } ] }, { "start" : 170, "end" : 214, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 0.39, "score" : 19.6, "location-fragments" : [ { "start" : 170, "end" : 214, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-14, "score" : 64.5, "model-ac" : "SM00320" }, { "signature" : { "accession" : "PTHR12442", "name" : "DYNEIN INTERMEDIATE CHAIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 425, "hmmStart" : 82, "hmmEnd" : 484, "hmmLength" : 496, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 429, "location-fragments" : [ { "start" : 12, "end" : 425, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-46, "familyName" : "WD REPEAT-CONTAINING PROTEIN 34", "score" : 161.9, "model-ac" : "PTHR12442" } ], "xref" : [ { "name" : "XP_018910176.1 PREDICTED: WD repeat-containing protein 34-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910176.1" } ] },{ "sequence" : "MGISIDMQARDNAKYVQALLRIPDLFIERVVIPVYQPEIIYSLTGKKKEYQSYANVLFALVREVLEKKMEHRAELRQTSGVSYEAGTKLFLDILLDKFEASEKKDMDLLTYETGELFVAGTVTISTMVSWVCLLSGVFPEVGDKLREEIDSCVKDAPNATIEDCAKLEYLDLVVKEALRHFTVPFIARKAKKDIEVPDVGTVPENTRLLVSLLSLHHDARYWEKPYEFYPEHFLPENVEKRPKFAYIPFSTGMRDCPGAKYAIQSMKVEVVRILSQFKIASARMKPWKNPFTELSLGFGFTFVPTRGWLVTAELRNQSSD", "md5" : "260a6e5b3bf4da54d478d4d67bc71dc1", "matches" : [ { "signature" : { "accession" : "PS00086", "name" : "CYTOCHROME_P450", "description" : "Cytochrome P450 cysteine heme-iron ligand signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR017972", "name" : "Cyt_P450_CS", "description" : "Cytochrome P450, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 249, "end" : 258, "level" : "STRONG", "cigarAlignment" : "2M1I7M", "alignment" : "FStGMRDCPG", "location-fragments" : [ { "start" : 249, "end" : 258, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00086" }, { "signature" : { "accession" : "G3DSA:1.10.630.10", "name" : "Cytochrome p450", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036396", "name" : "Cyt_P450_sf", "description" : "Cytochrome P450 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 299, "hmmStart" : 155, "hmmEnd" : 415, "hmmLength" : 446, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-59, "score" : 203.2, "envelopeStart" : 1, "envelopeEnd" : 299, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 299, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-59, "score" : 203.4, "model-ac" : "3dbgA00" }, { "signature" : { "accession" : "SSF48264", "name" : "Cytochrome P450", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036396", "name" : "Cyt_P450_sf", "description" : "Cytochrome P450 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 315, "hmmLength" : 463, "location-fragments" : [ { "start" : 1, "end" : 315, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.12E-62, "model-ac" : "0054912" }, { "signature" : { "accession" : "PR00385", "name" : "P450", "description" : "P450 superfamily signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001128", "name" : "Cyt_P450", "description" : "Cytochrome P450", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 256, "end" : 267, "pvalue" : 0.0217, "score" : 30.3, "motifNumber" : 5, "location-fragments" : [ { "start" : 256, "end" : 267, "dc-status" : "CONTINUOUS" } ] }, { "start" : 172, "end" : 183, "pvalue" : 0.00147, "score" : 33.58, "motifNumber" : 3, "location-fragments" : [ { "start" : 172, "end" : 183, "dc-status" : "CONTINUOUS" } ] }, { "start" : 119, "end" : 136, "pvalue" : 4.91E-4, "score" : 30.5, "motifNumber" : 1, "location-fragments" : [ { "start" : 119, "end" : 136, "dc-status" : "CONTINUOUS" } ] }, { "start" : 247, "end" : 256, "pvalue" : 1.03E-4, "score" : 53.72, "motifNumber" : 4, "location-fragments" : [ { "start" : 247, "end" : 256, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-6, "graphscan" : "I.III", "model-ac" : "PR00385" }, { "signature" : { "accession" : "PF00067", "name" : "p450", "description" : "Cytochrome P450", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001128", "name" : "Cyt_P450", "description" : "Cytochrome P450", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 291, "hmmStart" : 158, "hmmEnd" : 448, "hmmLength" : 463, "hmmBounds" : "INCOMPLETE", "evalue" : 3.7E-57, "score" : 194.1, "envelopeStart" : 1, "envelopeEnd" : 305, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 291, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-57, "score" : 194.3, "model-ac" : "PF00067" }, { "signature" : { "accession" : "PTHR24291:SF140", "name" : "CYTOCHROME P450 4C3-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 288, "hmmStart" : 171, "hmmEnd" : 457, "hmmLength" : 481, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 316, "location-fragments" : [ { "start" : 1, "end" : 288, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-70, "familyName" : "CYTOCHROME P450 4C3-RELATED", "score" : 241.0, "model-ac" : "PTHR24291:SF140" }, { "signature" : { "accession" : "PTHR24291", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 288, "hmmStart" : 171, "hmmEnd" : 457, "hmmLength" : 481, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 316, "location-fragments" : [ { "start" : 1, "end" : 288, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-70, "familyName" : "CYTOCHROME P450 4C3-RELATED", "score" : 241.0, "model-ac" : "PTHR24291" }, { "signature" : { "accession" : "PR00463", "name" : "EP450I", "description" : "E-class P450 group I signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR002401", "name" : "Cyt_P450_E_grp-I", "description" : "Cytochrome P450, E-class, group I", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016705" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" }, { "name" : "heme binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0020037" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 246, "end" : 256, "pvalue" : 6.03E-5, "score" : 50.15, "motifNumber" : 8, "location-fragments" : [ { "start" : 246, "end" : 256, "dc-status" : "CONTINUOUS" } ] }, { "start" : 108, "end" : 125, "pvalue" : 1.1E-4, "score" : 35.1, "motifNumber" : 4, "location-fragments" : [ { "start" : 108, "end" : 125, "dc-status" : "CONTINUOUS" } ] }, { "start" : 211, "end" : 235, "pvalue" : 2.45E-10, "score" : 40.08, "motifNumber" : 7, "location-fragments" : [ { "start" : 211, "end" : 235, "dc-status" : "CONTINUOUS" } ] }, { "start" : 128, "end" : 154, "pvalue" : 2.07E-6, "score" : 29.61, "motifNumber" : 5, "location-fragments" : [ { "start" : 128, "end" : 154, "dc-status" : "CONTINUOUS" } ] }, { "start" : 256, "end" : 279, "pvalue" : 0.0012, "score" : 22.49, "motifNumber" : 9, "location-fragments" : [ { "start" : 256, "end" : 279, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-21, "graphscan" : "...Ii.IIi", "model-ac" : "PR00463" } ], "xref" : [ { "name" : "XP_018909759.1 PREDICTED: cytochrome P450 3A19-like [Bemisia tabaci]", "id" : "XP_018909759.1" } ] },{ "sequence" : "MSAYHRTLSVSVEVERGKYQDPSVFVSEMALQLIVQFLLALAVLNYVDSNLGDYQRYVEVKKYYTKKHKYNDGVVRLVNGRTAAEGNVEVFHDGRWGSVCDDEFDEAEARVVCRQLGYRDYQRVTRDSYFGQARKKFWIDDVFCGGSEYELAQCKFSGWGNHDCTPQEAAGVVCQQTNDVKSNWTTNYSTKKSSYSSYSYKQRIQDMTGGHLSIRLTGGRVREEGQVEIRVGYSDWGVICGDGWSLREANVVCRQLGLGHATYAAHGHFYSRYSHNVLLTDVECRGDEASLMYCTHTKSPKTCTNHRNGGAGVICTREMADLVIDAGEIERSAYLQDRSLHSLQCAMEENCLASSAYRIKSSRYDWYSQTRRLLRFTARIVNTGTADFRPAVPKHLWQFHQCHMHFHSMEVFATFDVFDGSGRKVAEGHKASFCLEDNQCLRGTHPEYACANFGEQGISVNCTDIYRHDIDCQWVDITDLKPGHYTLRVAVNPEFKVGEMSFENNAADCALYYSESSARVYNCRLTRP", "md5" : "f6e03d99b87ea710fe5a4459d1455119", "matches" : [ { "signature" : { "accession" : "G3DSA:3.10.250.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036772", "name" : "SRCR-like_dom_sf", "description" : "SRCR-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 209, "end" : 322, "hmmStart" : 9, "hmmEnd" : 111, "hmmLength" : 119, "hmmBounds" : "COMPLETE", "evalue" : 3.6E-27, "score" : 96.5, "envelopeStart" : 209, "envelopeEnd" : 322, "postProcessed" : true, "location-fragments" : [ { "start" : 209, "end" : 322, "dc-status" : "CONTINUOUS" } ] }, { "start" : 67, "end" : 182, "hmmStart" : 6, "hmmEnd" : 111, "hmmLength" : 119, "hmmBounds" : "COMPLETE", "evalue" : 7.9E-39, "score" : 134.1, "envelopeStart" : 67, "envelopeEnd" : 182, "postProcessed" : true, "location-fragments" : [ { "start" : 67, "end" : 182, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-65, "score" : 218.0, "model-ac" : "1by2A00" }, { "signature" : { "accession" : "PR00258", "name" : "SPERACTRCPTR", "description" : "Speract receptor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001190", "name" : "SRCR", "description" : "SRCR domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "scavenger receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005044" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 94, "end" : 105, "pvalue" : 2.25E-5, "score" : 61.48, "motifNumber" : 2, "location-fragments" : [ { "start" : 94, "end" : 105, "dc-status" : "CONTINUOUS" } ] }, { "start" : 140, "end" : 154, "pvalue" : 5.89E-5, "score" : 47.55, "motifNumber" : 4, "location-fragments" : [ { "start" : 140, "end" : 154, "dc-status" : "CONTINUOUS" } ] }, { "start" : 163, "end" : 175, "pvalue" : 9.62E-4, "score" : 46.73, "motifNumber" : 5, "location-fragments" : [ { "start" : 163, "end" : 175, "dc-status" : "CONTINUOUS" } ] }, { "start" : 75, "end" : 91, "pvalue" : 1.68E-7, "score" : 46.61, "motifNumber" : 1, "location-fragments" : [ { "start" : 75, "end" : 91, "dc-status" : "CONTINUOUS" } ] }, { "start" : 109, "end" : 119, "pvalue" : 3.38E-5, "score" : 66.9, "motifNumber" : 3, "location-fragments" : [ { "start" : 109, "end" : 119, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.9E-18, "graphscan" : "IIIII", "model-ac" : "PR00258" }, { "signature" : { "accession" : "PR00074", "name" : "LYSYLOXIDASE", "description" : "Protein-lysine 6-oxidase precursor signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR001695", "name" : "Lysyl_oxidase", "description" : "Lysyl oxidase", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016641" }, { "name" : "copper ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005507" } ], "pathwayXRefs" : [ { "name" : "Elastic fibre formation", "databaseName" : "Reactome", "id" : "R-HSA-1566948" }, { "name" : "Crosslinking of collagen fibrils", "databaseName" : "Reactome", "id" : "R-HSA-2243919" } ] } }, "locations" : [ { "start" : 492, "end" : 509, "pvalue" : 1.64E-4, "score" : 38.89, "motifNumber" : 9, "location-fragments" : [ { "start" : 492, "end" : 509, "dc-status" : "CONTINUOUS" } ] }, { "start" : 472, "end" : 491, "pvalue" : 1.02E-10, "score" : 67.5, "motifNumber" : 8, "location-fragments" : [ { "start" : 472, "end" : 491, "dc-status" : "CONTINUOUS" } ] }, { "start" : 401, "end" : 421, "pvalue" : 4.54E-7, "score" : 45.24, "motifNumber" : 5, "location-fragments" : [ { "start" : 401, "end" : 421, "dc-status" : "CONTINUOUS" } ] }, { "start" : 329, "end" : 353, "pvalue" : 7.11E-10, "score" : 56.0, "motifNumber" : 2, "location-fragments" : [ { "start" : 329, "end" : 353, "dc-status" : "CONTINUOUS" } ] }, { "start" : 449, "end" : 471, "pvalue" : 1.8E-4, "score" : 39.13, "motifNumber" : 7, "location-fragments" : [ { "start" : 449, "end" : 471, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.7E-28, "graphscan" : ".I..I.III.", "model-ac" : "PR00074" }, { "signature" : { "accession" : "PF01186", "name" : "Lysyl_oxidase", "description" : "Lysyl oxidase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001695", "name" : "Lysyl_oxidase", "description" : "Lysyl oxidase", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016641" }, { "name" : "copper ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005507" } ], "pathwayXRefs" : [ { "name" : "Elastic fibre formation", "databaseName" : "Reactome", "id" : "R-HSA-1566948" }, { "name" : "Crosslinking of collagen fibrils", "databaseName" : "Reactome", "id" : "R-HSA-2243919" } ] } }, "locations" : [ { "start" : 321, "end" : 524, "hmmStart" : 2, "hmmEnd" : 201, "hmmLength" : 202, "hmmBounds" : "INCOMPLETE", "evalue" : 2.3E-96, "score" : 321.2, "envelopeStart" : 320, "envelopeEnd" : 525, "postProcessed" : true, "location-fragments" : [ { "start" : 321, "end" : 524, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-96, "score" : 322.3, "model-ac" : "PF01186" }, { "signature" : { "accession" : "PF00530", "name" : "SRCR", "description" : "Scavenger receptor cysteine-rich domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001190", "name" : "SRCR", "description" : "SRCR domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "scavenger receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005044" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 78, "end" : 175, "hmmStart" : 1, "hmmEnd" : 100, "hmmLength" : 100, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-27, "score" : 95.6, "envelopeStart" : 78, "envelopeEnd" : 175, "postProcessed" : true, "location-fragments" : [ { "start" : 78, "end" : 175, "dc-status" : "CONTINUOUS" } ] }, { "start" : 218, "end" : 316, "hmmStart" : 2, "hmmEnd" : 100, "hmmLength" : 100, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 7.8E-23, "score" : 80.8, "envelopeStart" : 217, "envelopeEnd" : 316, "postProcessed" : true, "location-fragments" : [ { "start" : 218, "end" : 316, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-50, "score" : 169.5, "model-ac" : "PF00530" }, { "signature" : { "accession" : "PS00420", "name" : "SRCR_1", "description" : "SRCR domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR001190", "name" : "SRCR", "description" : "SRCR domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "scavenger receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005044" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 80, "end" : 117, "level" : "STRONG", "cigarAlignment" : "1M5I1M2I1M6I2M2I1M3I1M8I1M3I1M", "alignment" : "GrtaaeGnvEvfhdgrWGsvCddeFdeaearvvCrqlG", "location-fragments" : [ { "start" : 80, "end" : 117, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00420" }, { "signature" : { "accession" : "PTHR45817", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 56, "end" : 527, "hmmStart" : 14, "hmmEnd" : 474, "hmmLength" : 475, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 29, "envelopeEnd" : 528, "location-fragments" : [ { "start" : 56, "end" : 527, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-192, "familyName" : "LYSYL OXIDASE-LIKE-RELATED", "score" : 642.3, "model-ac" : "PTHR45817" }, { "signature" : { "accession" : "SM00202", "name" : "SR_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR017448", "name" : "SRCR-like_dom", "description" : "SRCR-like domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 75, "end" : 175, "hmmStart" : 1, "hmmEnd" : 118, "hmmLength" : 118, "hmmBounds" : "COMPLETE", "evalue" : 6.9E-46, "score" : 168.4, "location-fragments" : [ { "start" : 75, "end" : 175, "dc-status" : "CONTINUOUS" } ] }, { "start" : 214, "end" : 316, "hmmStart" : 1, "hmmEnd" : 118, "hmmLength" : 118, "hmmBounds" : "COMPLETE", "evalue" : 5.0E-24, "score" : 95.8, "location-fragments" : [ { "start" : 214, "end" : 316, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-75, "score" : 264.3, "model-ac" : "SM00202" }, { "signature" : { "accession" : "PS50287", "name" : "SRCR_2", "description" : "SRCR domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001190", "name" : "SRCR", "description" : "SRCR domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "scavenger receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005044" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 75, "end" : 175, "score" : 29.365, "alignment" : "VRLVNGRTAAEGNVEVFHDGRWGSVCDDEFDEAEARVVCRQLGYRDYQRVTRDSYFGQARKKFWIDDVFCGGSEYELAQCKFSGWGNHDCTPQEAAGVVCQ", "location-fragments" : [ { "start" : 75, "end" : 175, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50287" }, { "signature" : { "accession" : "PTHR45817:SF4", "name" : "LYSYL OXIDASE-LIKE-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 56, "end" : 527, "hmmStart" : 14, "hmmEnd" : 474, "hmmLength" : 475, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 29, "envelopeEnd" : 528, "location-fragments" : [ { "start" : 56, "end" : 527, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-192, "familyName" : "LYSYL OXIDASE-LIKE-RELATED", "score" : 642.3, "model-ac" : "PTHR45817:SF4" }, { "signature" : { "accession" : "PS50287", "name" : "SRCR_2", "description" : "SRCR domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001190", "name" : "SRCR", "description" : "SRCR domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" }, { "name" : "scavenger receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005044" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 214, "end" : 316, "score" : 25.945, "alignment" : "IRLTGGRVREEGQVEIRVGYSdWGVICGDGWSLREANVVCRQLGLGHATYAAHGHFYSRYSHNVLLTDVECRGDEASLMYCT-HTKSPKTCTnhRNGGAGVICT", "location-fragments" : [ { "start" : 214, "end" : 316, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50287" }, { "signature" : { "accession" : "SSF56487", "name" : "SRCR-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036772", "name" : "SRCR-like_dom_sf", "description" : "SRCR-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 74, "end" : 177, "hmmLength" : 116, "location-fragments" : [ { "start" : 74, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.15E-36, "model-ac" : "0035772" }, { "signature" : { "accession" : "SSF56487", "name" : "SRCR-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036772", "name" : "SRCR-like_dom_sf", "description" : "SRCR-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016020" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 210, "end" : 321, "hmmLength" : 116, "location-fragments" : [ { "start" : 210, "end" : 321, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.01E-27, "model-ac" : "0035772" } ], "xref" : [ { "name" : "XP_018909897.1 PREDICTED: lysyl oxidase homolog 3-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909897.1" } ] },{ "sequence" : "MIKCCSTRRSVLRPFAAILVIPAVYILCRSAFSFVTSRHQLQTSHESVVYIRDGQRHLLGMDYGGIANCSPAKSHHFPELTLPGGVIVNILVAALVTGYLFVALASICDHYFLHSIKLICKKLDLSTDVAGATLMSMATSSPELFINLIGTFLTKGDIGVSTVVGSGVWNMLAVPCFCSLFTSAPVKVDYWPLTRDSLVYGVSVLLLAYAVRDGRVNQNEATVMVVLYLSYIVVMHYNKRIRYAIESFCRRLAGRDAEETTWLLMPCPAKYTNNFNNGEDFLDLEEDEGLGRLYKWPSDYSLCENIGWLFTWPIRFLLHYTVPSCHKPGTHNLFALTFLMCVVWIGICSYTIAWMITIIGNELSIPDSVMGLSFIAAGMSIPETVSCVIVSKKGNGTMALSNSFGSSTFDILLCLGLPWLIKAVYFSSSGVITIHSKGLQYSIFLLLALLVLVYAMFAANRFTMDKKIGWTCLVLYIVSITLSILIELNVFFIGNLPSC", "md5" : "fb5eefe99fa89fe96ff4b7c923c11f64", "matches" : [ { "signature" : { "accession" : "TIGR00367", "name" : "TIGR00367", "description" : "TIGR00367: K+-dependent Na+/Ca+ exchanger homolog", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR004481", "name" : "K/Na/Ca-exchanger", "description" : "Sodium/potassium/calcium exchanger", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Sodium/Calcium exchangers", "databaseName" : "Reactome", "id" : "R-HSA-425561" } ] } }, "locations" : [ { "start" : 96, "end" : 478, "hmmStart" : 6, "hmmEnd" : 311, "hmmLength" : 312, "hmmBounds" : "INCOMPLETE", "evalue" : 5.9E-61, "score" : 204.2, "envelopeStart" : 90, "envelopeEnd" : 479, "postProcessed" : false, "location-fragments" : [ { "start" : 96, "end" : 478, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-61, "score" : 204.6, "model-ac" : "TIGR00367" }, { "signature" : { "accession" : "PTHR10846", "name" : "SODIUM/POTASSIUM/CALCIUM EXCHANGER", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR004481", "name" : "K/Na/Ca-exchanger", "description" : "Sodium/potassium/calcium exchanger", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Sodium/Calcium exchangers", "databaseName" : "Reactome", "id" : "R-HSA-425561" } ] } }, "locations" : [ { "start" : 68, "end" : 499, "hmmStart" : 115, "hmmEnd" : 561, "hmmLength" : 563, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 63, "envelopeEnd" : 499, "location-fragments" : [ { "start" : 68, "end" : 499, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.4E-134, "familyName" : "", "score" : 450.0, "model-ac" : "PTHR10846" }, { "signature" : { "accession" : "G3DSA:1.20.1420.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 319, "end" : 486, "hmmStart" : 88, "hmmEnd" : 214, "hmmLength" : 221, "hmmBounds" : "COMPLETE", "evalue" : 4.6E-23, "score" : 83.7, "envelopeStart" : 319, "envelopeEnd" : 486, "postProcessed" : true, "location-fragments" : [ { "start" : 319, "end" : 486, "dc-status" : "CONTINUOUS" } ] }, { "start" : 125, "end" : 249, "hmmStart" : 2, "hmmEnd" : 111, "hmmLength" : 221, "hmmBounds" : "COMPLETE", "evalue" : 5.8E-22, "score" : 80.1, "envelopeStart" : 125, "envelopeEnd" : 249, "postProcessed" : true, "location-fragments" : [ { "start" : 125, "end" : 249, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-46, "score" : 158.8, "model-ac" : "3v5uA02" }, { "signature" : { "accession" : "PTHR10846:SF59", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 68, "end" : 499, "hmmStart" : 115, "hmmEnd" : 561, "hmmLength" : 563, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 63, "envelopeEnd" : 499, "location-fragments" : [ { "start" : 68, "end" : 499, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.4E-134, "familyName" : "", "score" : 450.0, "model-ac" : "PTHR10846:SF59" }, { "signature" : { "accession" : "PF01699", "name" : "Na_Ca_ex", "description" : "Sodium/calcium exchanger protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR004837", "name" : "NaCa_Exmemb", "description" : "Sodium/calcium exchanger membrane region", "type" : "DOMAIN", "goXRefs" : [ { "name" : "transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055085" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ { "name" : "Sodium/Calcium exchangers", "databaseName" : "Reactome", "id" : "R-HSA-425561" } ] } }, "locations" : [ { "start" : 95, "end" : 234, "hmmStart" : 3, "hmmEnd" : 148, "hmmLength" : 151, "hmmBounds" : "INCOMPLETE", "evalue" : 7.4E-18, "score" : 64.9, "envelopeStart" : 93, "envelopeEnd" : 237, "postProcessed" : true, "location-fragments" : [ { "start" : 95, "end" : 234, "dc-status" : "CONTINUOUS" } ] }, { "start" : 334, "end" : 484, "hmmStart" : 2, "hmmEnd" : 150, "hmmLength" : 151, "hmmBounds" : "INCOMPLETE", "evalue" : 9.7E-22, "score" : 77.5, "envelopeStart" : 333, "envelopeEnd" : 485, "postProcessed" : true, "location-fragments" : [ { "start" : 334, "end" : 484, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.8E-39, "score" : 133.0, "model-ac" : "PF01699" } ], "xref" : [ { "name" : "XP_018909616.1 PREDICTED: sodium/potassium/calcium exchanger 3-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909616.1" } ] },{ "sequence" : "MVVTCKMVGTRFMVQWEEHPSHLSTRLGRLLEAQAFVDVTLMCATHSLRVHGSVLAACSPYFEDLLKLQVGHHPLIMLKDMKFCVLRALIEFMYCGETSITEADLRPLLDAAKFFKVKGLSSMTAEVLSDLPQSKVSQTSVSEEGKNVTCCKTPHTSTASTLSTSGANFIKSSKKTSIVRPRKSIAPPKIDSVAVEMNDSSGLPQDESAQILLSLSGNNKVVQRGSRGRGSNNRLLTQGPGRPPNKPIVISNCSFGSADSQIETRSKLVNTFEPRKRGRKKQQIASVSSSSRELLDGSNQSVSSLKSFESSNSIIDNFKMLHRDTKYSKLLSNSSDPKLNSITANMEKSPLLASLLSKEDSIQGKKNALKSGVVDIKSPSVSGSTEYLEALKAAGLPTDVPIIVDTGDGNYVTLTEDVFMDVLSSSESLQFQVTEETLDDSVSITEGVVMQDGSIVTEEGRELVAEPNSSKKLLSGHFKQYSKPEPPDLFTTLGGKSTISNEKSDITETVTETLKSSASDDPDAVVLVEVKGNQVVRYVVSSKEINALKALNEEKKWQKAGFDSTAPISNSSKKNSTKIAEINLTLNDSEAPKKSYITEFIETGSGLTSVAKAICERLPVKVYKENLSTKDSDPLMVNNAFVDKVNRSKLSTSHAYEALAMMCNDETKEERHQKPRQSNIENIELMQNSEMEISSITNESQLINTNSDEYIFVSEESQMRDESHLHGMDPNFNQVHMMNGARNVVLLKNKNGAPLMYVEDTAEPLMSNRIIEMEGFGSLQKDSKSIALKQCLGEGEDEQFQYVLDSSSVDKEMLDDSNSNQSYSNMVLYSNKDTSLEDAGVKYQMVDDQFSDRMRENKMLSNILLNSTPEIEDELIMNEENDVKSLGMINQVLNTTDQLNENDVTESSGYHSASIEFHEENDNSAFGDENGVGSKEDNVKYLSKETVFSENSENDNFHLVDSREKSEDFCSAPKNSSIDVPFMPKSKSNESSISDRVLRKRRSSSSCDAKQNSMKNCVSVEKRNKLLNDNHNENVVIMGNGDENALEESQFFGNGLTDTMMNSQLIDGNNLS", "md5" : "6b22595c6e67b3181de667a16c94b5ee", "matches" : [ { "signature" : { "accession" : "cd18315", "name" : "BTB_POZ_BAB-like", "description" : "BTB_POZ_BAB-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 36, "end" : 119, "sites" : [ ], "evalue" : 1.17326E-28, "score" : 108.021, "location-fragments" : [ { "start" : 36, "end" : 119, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18315" }, { "signature" : { "accession" : "SSF54695", "name" : "POZ domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011333", "name" : "SKP1/BTB/POZ_sf", "description" : "SKP1/BTB/POZ domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 128, "hmmLength" : 122, "location-fragments" : [ { "start" : 13, "end" : 128, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.1E-24, "model-ac" : "0043098" }, { "signature" : { "accession" : "PTHR23110", "name" : "BTB DOMAIN TRANSCRIPTION FACTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 236, "hmmStart" : 3, "hmmEnd" : 218, "hmmLength" : 397, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 366, "location-fragments" : [ { "start" : 11, "end" : 236, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-41, "familyName" : "PROTEIN JIM LOVELL", "score" : 144.8, "model-ac" : "PTHR23110" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 985, "end" : 1011, "location-fragments" : [ { "start" : 985, "end" : 1011, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.710.10", "name" : "Potassium Channel Kv1.1; Chain A", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 163, "hmmStart" : 7, "hmmEnd" : 125, "hmmLength" : 156, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-25, "score" : 92.0, "envelopeStart" : 12, "envelopeEnd" : 163, "postProcessed" : true, "location-fragments" : [ { "start" : 12, "end" : 163, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-26, "score" : 93.7, "model-ac" : "4u2nA01" }, { "signature" : { "accession" : "PF00651", "name" : "BTB", "description" : "BTB/POZ domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000210", "name" : "BTB/POZ_dom", "description" : "BTB/POZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 29, "end" : 128, "hmmStart" : 3, "hmmEnd" : 107, "hmmLength" : 111, "hmmBounds" : "INCOMPLETE", "evalue" : 5.5E-22, "score" : 78.1, "envelopeStart" : 27, "envelopeEnd" : 131, "postProcessed" : true, "location-fragments" : [ { "start" : 29, "end" : 128, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-22, "score" : 79.7, "model-ac" : "PF00651" }, { "signature" : { "accession" : "PS50097", "name" : "BTB", "description" : "BTB domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000210", "name" : "BTB/POZ_dom", "description" : "BTB/POZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 102, "score" : 17.645, "alignment" : "VDVTLMCATHSLRVHGSVLAACSPYFEDLLKLQVGHHP-LIMLKDMKFCVLRALIEFMYCGETSITE", "location-fragments" : [ { "start" : 37, "end" : 102, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50097" }, { "signature" : { "accession" : "PTHR23110:SF78", "name" : "PROTEIN JIM LOVELL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 11, "end" : 236, "hmmStart" : 3, "hmmEnd" : 218, "hmmLength" : 397, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 366, "location-fragments" : [ { "start" : 11, "end" : 236, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-41, "familyName" : "PROTEIN JIM LOVELL", "score" : 144.8, "model-ac" : "PTHR23110:SF78" }, { "signature" : { "accession" : "SM00225", "name" : "BTB_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000210", "name" : "BTB/POZ_dom", "description" : "BTB/POZ domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 37, "end" : 132, "hmmStart" : 1, "hmmEnd" : 114, "hmmLength" : 114, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-20, "score" : 83.8, "location-fragments" : [ { "start" : 37, "end" : 132, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-20, "score" : 83.8, "model-ac" : "SM00225" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 220, "end" : 239, "location-fragments" : [ { "start" : 220, "end" : 239, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 220, "end" : 245, "location-fragments" : [ { "start" : 220, "end" : 245, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 992, "end" : 1006, "location-fragments" : [ { "start" : 992, "end" : 1006, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910510.1 PREDICTED: uncharacterized protein LOC109039477 isoform X1 [Bemisia tabaci]", "id" : "XP_018910510.1" } ] },{ "sequence" : "MVNKQKKAGGPQKRAKPYTAMQMEYLTEAIRKRQKVIECKKTDTVVNAEKTVAWQDVTNEFNAHLTPEDGPRTLVQLKGKWKQMKRDAGKVIREIYREWGGTGGGPQWKEKLPALEAKIFSICPKSFLAARTNKYDSDGGQIVAESDCDEEQSDYDEENGVDENNLNSCNTRKEAHCSMPEFQQILDSTIPIDGANAGGAEVQMQNSGSEAEDEFEDYILEVIEDCGDTSSTSVAPSETLNHGQSLEPPSTSKSQGSSNPGTSKKSPDTEDSSISKKVDWSHYNVPALRSKKSDALTLKKGKKRKLYGKTIQEKYEQDRQVLIETQRDYYITLQKQNIEKHNKEMELKNLEADYWCARKAAEERYWLQRIEREEKEAALRMKLVEEELKVMSRGTSSSNDYNDNTAF", "md5" : "07da38db43fb190f09a895dd2a741101", "matches" : [ { "signature" : { "accession" : "PTHR23098", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR026753", "name" : "NAIF1", "description" : "Nuclear apoptosis-inducing factor 1", "type" : "FAMILY", "goXRefs" : [ { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" }, { "name" : "apoptotic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006915" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 348, "hmmStart" : 52, "hmmEnd" : 350, "hmmLength" : 373, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 388, "location-fragments" : [ { "start" : 8, "end" : 348, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-21, "familyName" : "FAMILY NOT NAMED", "score" : 77.6, "model-ac" : "PTHR23098" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 142, "end" : 166, "location-fragments" : [ { "start" : 142, "end" : 166, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 190, "end" : 277, "location-fragments" : [ { "start" : 190, "end" : 277, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 226, "end" : 268, "location-fragments" : [ { "start" : 226, "end" : 268, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 367, "end" : 387, "location-fragments" : [ { "start" : 367, "end" : 387, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 333, "end" : 353, "location-fragments" : [ { "start" : 333, "end" : 353, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 143, "end" : 161, "location-fragments" : [ { "start" : 143, "end" : 161, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF13873", "name" : "Myb_DNA-bind_5", "description" : "Myb/SANT-like DNA-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR028002", "name" : "Myb_DNA-bind_5", "description" : "Myb/SANT-like DNA-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 90, "hmmStart" : 1, "hmmEnd" : 74, "hmmLength" : 78, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.7E-14, "score" : 53.6, "envelopeStart" : 14, "envelopeEnd" : 94, "postProcessed" : true, "location-fragments" : [ { "start" : 14, "end" : 90, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-14, "score" : 53.6, "model-ac" : "PF13873" } ], "xref" : [ { "name" : "XP_018910419.1 PREDICTED: uncharacterized protein LOC109039405 [Bemisia tabaci]", "id" : "XP_018910419.1" } ] },{ "sequence" : "MKIRKHVRNKRRVVKNVKKIYKKLRAKQVPKFDCEEIKEAWARGRTLGQNFKDMGLAVDPNKAVKTTFGTQDSEEEDSDSVPQLIPIPKKKHVAEALEADAKAPRERKIRLPDGEVRFIAQLMTRYGDNYEKMARDNRNKWQWTPAQFRAKIKRFMTIDDQYKFYLNNRKAGCKWRPEDPNFGKNSNLERDLF", "md5" : "e6e7d6d4c8d7860f9418c6f5f1342c81", "matches" : [ { "signature" : { "accession" : "PTHR13243", "name" : "HSPC111 PROTEIN-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR019002", "name" : "Ribosome_biogenesis_Nop16", "description" : "Ribosome biogenesis protein Nop16", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3, "end" : 170, "hmmStart" : 4, "hmmEnd" : 177, "hmmLength" : 184, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 173, "location-fragments" : [ { "start" : 3, "end" : 170, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-37, "familyName" : "HSPC111 PROTEIN-RELATED", "score" : 132.2, "model-ac" : "PTHR13243" }, { "signature" : { "accession" : "PF09420", "name" : "Nop16", "description" : "Ribosome biogenesis protein Nop16", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR019002", "name" : "Ribosome_biogenesis_Nop16", "description" : "Ribosome biogenesis protein Nop16", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 71, "hmmStart" : 4, "hmmEnd" : 67, "hmmLength" : 210, "hmmBounds" : "INCOMPLETE", "evalue" : 1.1E-7, "score" : 32.1, "envelopeStart" : 3, "envelopeEnd" : 84, "postProcessed" : true, "location-fragments" : [ { "start" : 8, "end" : 71, "dc-status" : "CONTINUOUS" } ] }, { "start" : 78, "end" : 155, "hmmStart" : 138, "hmmEnd" : 209, "hmmLength" : 210, "hmmBounds" : "INCOMPLETE", "evalue" : 3.5E-16, "score" : 59.9, "envelopeStart" : 65, "envelopeEnd" : 156, "postProcessed" : true, "location-fragments" : [ { "start" : 78, "end" : 155, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-25, "score" : 89.5, "model-ac" : "PF09420" } ], "xref" : [ { "name" : "XP_018909942.1 PREDICTED: nucleolar protein 16 [Bemisia tabaci]", "id" : "XP_018909942.1" } ] },{ "sequence" : "MIPMHVCRTRLPKQCQKQMEYHRKTHLLEVPQPGIAATGVSIYFYYLAYCEDAIERVCLLPKEIFHEVVRMVGSRVYVGGLPYGCREKDLEKFFKGYGRIRDILLKNGYGFVEFEDNRDAEDAVYELNGRPLMGERITVERARGTDRSRRGFGGGGRFGGGGGRYGGGRRRTPDTFRYGPPRRTDYRVIVENLSSRISWQDLKDFMRKAGEVSYADAHRINRNEGVVEFTSYSEMKTAIEKLDGTELNGRRIRLIEDKRKSRRSYSSSSRSRSRSRSRSRSNRNRSRSHSKSARKSRSRSRLPAKKRDSKSPSRSRSPVADKSSRSPSKKRSRSRSPAPKKHSRSSSSHSKSHSRSPVKKRSKARSPSADSDRRYSESPRKDRSASPGMKNGDRSGDED", "md5" : "da5bfce36122953205b067159c602445", "matches" : [ { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 74, "end" : 144, "score" : 18.325, "alignment" : "SRVYVGGLPYGCREKDLEKFFKGYGRIRDILL-------KNGYGFVEFEDNRDAEDAVYELNGRPLMGERITVERARG", "location-fragments" : [ { "start" : 74, "end" : 144, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" }, { "signature" : { "accession" : "cd12600", "name" : "RRM2_SRSF4_like", "description" : "RRM2_SRSF4_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 186, "end" : 257, "sites" : [ ], "evalue" : 4.05845E-46, "score" : 150.981, "location-fragments" : [ { "start" : 186, "end" : 257, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12600" }, { "signature" : { "accession" : "PF00076", "name" : "RRM_1", "description" : "RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 188, "end" : 253, "hmmStart" : 1, "hmmEnd" : 70, "hmmLength" : 70, "hmmBounds" : "COMPLETE", "evalue" : 4.0E-13, "score" : 49.0, "envelopeStart" : 188, "envelopeEnd" : 253, "postProcessed" : true, "location-fragments" : [ { "start" : 188, "end" : 253, "dc-status" : "CONTINUOUS" } ] }, { "start" : 76, "end" : 137, "hmmStart" : 1, "hmmEnd" : 69, "hmmLength" : 70, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 5.1E-19, "score" : 67.9, "envelopeStart" : 76, "envelopeEnd" : 138, "postProcessed" : true, "location-fragments" : [ { "start" : 76, "end" : 137, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.2E-35, "score" : 118.9, "model-ac" : "PF00076" }, { "signature" : { "accession" : "PTHR23147:SF55", "name" : "SERINE/ARGININE-RICH SPLICING FACTOR 4", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 74, "end" : 338, "hmmStart" : 2, "hmmEnd" : 261, "hmmLength" : 448, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 73, "envelopeEnd" : 342, "location-fragments" : [ { "start" : 74, "end" : 338, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-89, "familyName" : "SERINE/ARGININE-RICH SPLICING FACTOR 4", "score" : 302.1, "model-ac" : "PTHR23147:SF55" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 363, "end" : 399, "location-fragments" : [ { "start" : 363, "end" : 399, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 185, "end" : 258, "hmmStart" : 1, "hmmEnd" : 72, "hmmLength" : 77, "hmmBounds" : "COMPLETE", "evalue" : 3.3E-24, "score" : 86.6, "envelopeStart" : 185, "envelopeEnd" : 258, "postProcessed" : true, "location-fragments" : [ { "start" : 185, "end" : 258, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-45, "score" : 153.5, "model-ac" : "1wg4A01" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 265, "end" : 304, "location-fragments" : [ { "start" : 265, "end" : 304, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50102", "name" : "RRM", "description" : "Eukaryotic RNA Recognition Motif (RRM) profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 186, "end" : 259, "score" : 12.526, "alignment" : "YRVIVENLSSRISWQDLKDFMRKAGEVSYADAHR----INRNEGVVEFTSYSEMKTAIEKLDGTELNGRRIRLIEDKR", "location-fragments" : [ { "start" : 186, "end" : 259, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50102" }, { "signature" : { "accession" : "SM00360", "name" : "rrm1_1", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000504", "name" : "RRM_dom", "description" : "RNA recognition motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 187, "end" : 255, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 6.9E-12, "score" : 55.5, "location-fragments" : [ { "start" : 187, "end" : 255, "dc-status" : "CONTINUOUS" } ] }, { "start" : 75, "end" : 140, "hmmStart" : 1, "hmmEnd" : 121, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 2.3E-21, "score" : 87.0, "location-fragments" : [ { "start" : 75, "end" : 140, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-38, "score" : 142.5, "model-ac" : "SM00360" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 328, "end" : 362, "location-fragments" : [ { "start" : 328, "end" : 362, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.70.330", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR012677", "name" : "Nucleotide-bd_a/b_plait_sf", "description" : "Nucleotide-binding alpha-beta plait domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 71, "end" : 174, "hmmStart" : 14, "hmmEnd" : 108, "hmmLength" : 126, "hmmBounds" : "COMPLETE", "evalue" : 2.5E-23, "score" : 84.6, "envelopeStart" : 71, "envelopeEnd" : 174, "postProcessed" : true, "location-fragments" : [ { "start" : 71, "end" : 174, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-38, "score" : 132.1, "model-ac" : "4pkdB02" }, { "signature" : { "accession" : "cd12337", "name" : "RRM1_SRSF4_like", "description" : "RRM1_SRSF4_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR035585", "name" : "RRM1_SRSF4-like", "description" : "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "RNA Polymerase II Transcription Termination", "databaseName" : "Reactome", "id" : "R-HSA-73856" }, { "name" : "mRNA 3'-end processing", "databaseName" : "Reactome", "id" : "R-HSA-72187" }, { "name" : "mRNA Splicing - Major Pathway", "databaseName" : "Reactome", "id" : "R-HSA-72163" }, { "name" : "Transport of Mature mRNA derived from an Intron-Containing Transcript", "databaseName" : "Reactome", "id" : "R-HSA-159236" } ] } }, "locations" : [ { "start" : 75, "end" : 144, "sites" : [ ], "evalue" : 2.31594E-37, "score" : 127.828, "location-fragments" : [ { "start" : 75, "end" : 144, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd12337" }, { "signature" : { "accession" : "SSF54928", "name" : "RNA-binding domain, RBD", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035979", "name" : "RBD_domain_sf", "description" : "RNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "nucleic acid binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003676" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 75, "end" : 260, "hmmLength" : 183, "location-fragments" : [ { "start" : 183, "end" : 260, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 75, "end" : 154, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 1.43E-37, "model-ac" : "0049769" }, { "signature" : { "accession" : "PTHR23147", "name" : "SERINE/ARGININE RICH SPLICING FACTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 74, "end" : 338, "hmmStart" : 2, "hmmEnd" : 261, "hmmLength" : 448, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 73, "envelopeEnd" : 342, "location-fragments" : [ { "start" : 74, "end" : 338, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-89, "familyName" : "SERINE/ARGININE-RICH SPLICING FACTOR 4", "score" : 302.1, "model-ac" : "PTHR23147" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 253, "end" : 399, "location-fragments" : [ { "start" : 253, "end" : 399, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910448.1 PREDICTED: serine/arginine-rich splicing factor 5-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910448.1" } ] },{ "sequence" : "MNVIHCNKCGIFPEAKKSTKFFITNCGHLLCERCKGSDTCCICRNQCNKLLISEEMPSHVKDMLFEDLMDQMDHVYKLLQFRTDHFKKRLALASEMFLKYEKLKESYLKLTDDNKKVKTAYAKLMSEYKKRDAECKELKQAAQSHKKAPALKHALDSGAQSRAQPFFNNPKLSVVTPRKCNPLFKTPTSLSPFRTMNRERHPNYRNPAQYSGSSVGSAVRTPASDFNTPSSSVLRFNERESNNTARSPFVTPEVPIQDLKLGSWHGLRPKKPF", "md5" : "d136e8e839e657b2c6c6c6e422735538", "matches" : [ { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 121, "end" : 141, "location-fragments" : [ { "start" : 121, "end" : 141, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR22663", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR042123", "name" : "Vilya/Cst9/RNF212", "description" : "Vilya/Cst9/RNF212", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 254, "hmmStart" : 1, "hmmEnd" : 262, "hmmLength" : 335, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 263, "location-fragments" : [ { "start" : 1, "end" : 254, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-23, "familyName" : "UNCHARACTERIZED", "score" : 85.0, "model-ac" : "PTHR22663" } ], "xref" : [ { "name" : "XP_018910040.1 PREDICTED: RING finger protein 212B-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910040.1" } ] },{ "sequence" : "MEQAESANPQVWVFGYGSLCWHPGFEYEEAVTGYIKGYTRKFWQGSANHRGTSEKPGRVATLVDEKEGIVWGRAFKLTGDLALHYLNDRECKLGGYTTLHLDFYPKPDALLSDSTDSISTSTSTSSASSSTSSEISASDSSSTGFSSATTELSTSNSTTAHSTPSSTEGSETTAISVLNSSSSSKPFKALVFIATPANDLWLGEAPLNDIADHIVGCKGQSGYNVEYVLRLAHFMHEHIPEAKDNHLFTLEYLLLNKIEAANLCLNEMMGTKATAGSAGSSRGTTDTALPAPPQASYQFSARVPSKKLRCLNI", "md5" : "10b5a55bbef3616e9360a93847eafe0d", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 147, "end" : 174, "location-fragments" : [ { "start" : 147, "end" : 174, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF110857", "name" : "Gamma-glutamyl cyclotransferase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036568", "name" : "GGCT-like_sf", "description" : "Gamma-glutamyl cyclotransferase-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 10, "end" : 105, "hmmLength" : 151, "location-fragments" : [ { "start" : 10, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.71E-5, "model-ac" : "0044830" }, { "signature" : { "accession" : "cd06661", "name" : "GGCT_like", "description" : "GGCT_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR013024", "name" : "GGCT-like", "description" : "Gamma-glutamyl cyclotransferase-like", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 105, "sites" : [ { "description" : "putative active site pocket", "numLocations" : 7, "siteLocations" : [ { "start" : 89, "end" : 89, "residue" : "R" }, { "start" : 16, "end" : 16, "residue" : "Y" }, { "start" : 96, "end" : 96, "residue" : "Y" }, { "start" : 18, "end" : 18, "residue" : "S" }, { "start" : 19, "end" : 19, "residue" : "L" }, { "start" : 13, "end" : 13, "residue" : "V" }, { "start" : 90, "end" : 90, "residue" : "E" } ] }, { "description" : "dimerization interface", "numLocations" : 9, "siteLocations" : [ { "start" : 100, "end" : 100, "residue" : "H" }, { "start" : 102, "end" : 102, "residue" : "D" }, { "start" : 66, "end" : 66, "residue" : "K" }, { "start" : 97, "end" : 97, "residue" : "T" }, { "start" : 63, "end" : 63, "residue" : "V" }, { "start" : 96, "end" : 96, "residue" : "Y" }, { "start" : 99, "end" : 99, "residue" : "L" }, { "start" : 98, "end" : 98, "residue" : "T" }, { "start" : 64, "end" : 64, "residue" : "D" } ] }, { "description" : "putative catalytic residue", "numLocations" : 1, "siteLocations" : [ { "start" : 90, "end" : 90, "residue" : "E" } ] } ], "evalue" : 8.63597E-13, "score" : 61.5918, "location-fragments" : [ { "start" : 13, "end" : 105, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd06661" }, { "signature" : { "accession" : "PF04752", "name" : "ChaC", "description" : "ChaC-like protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006840", "name" : "ChaC", "description" : "Glutathione-specific gamma-glutamylcyclotransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "glutathione catabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006751" }, { "name" : "gamma-glutamylcyclotransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003839" } ], "pathwayXRefs" : [ { "name" : "5-oxo-L-proline metabolism", "databaseName" : "MetaCyc", "id" : "PWY-7942" }, { "name" : "Glutathione synthesis and recycling", "databaseName" : "Reactome", "id" : "R-HSA-174403" }, { "name" : "Glutathione metabolism", "databaseName" : "KEGG", "id" : "00480+4.3.2.7" } ] } }, "locations" : [ { "start" : 11, "end" : 252, "hmmStart" : 1, "hmmEnd" : 176, "hmmLength" : 181, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.6E-56, "score" : 191.2, "envelopeStart" : 11, "envelopeEnd" : 257, "postProcessed" : true, "location-fragments" : [ { "start" : 11, "end" : 252, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-58, "score" : 197.9, "model-ac" : "PF04752" }, { "signature" : { "accession" : "PTHR12192", "name" : "CATION TRANSPORT PROTEIN CHAC-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR006840", "name" : "ChaC", "description" : "Glutathione-specific gamma-glutamylcyclotransferase", "type" : "FAMILY", "goXRefs" : [ { "name" : "glutathione catabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006751" }, { "name" : "gamma-glutamylcyclotransferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003839" } ], "pathwayXRefs" : [ { "name" : "5-oxo-L-proline metabolism", "databaseName" : "MetaCyc", "id" : "PWY-7942" }, { "name" : "Glutathione synthesis and recycling", "databaseName" : "Reactome", "id" : "R-HSA-174403" }, { "name" : "Glutathione metabolism", "databaseName" : "KEGG", "id" : "00480+4.3.2.7" } ] } }, "locations" : [ { "start" : 6, "end" : 256, "hmmStart" : 5, "hmmEnd" : 180, "hmmLength" : 205, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 284, "location-fragments" : [ { "start" : 6, "end" : 256, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-62, "familyName" : "GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1", "score" : 211.7, "model-ac" : "PTHR12192" }, { "signature" : { "accession" : "PTHR12192:SF2", "name" : "GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 6, "end" : 256, "hmmStart" : 5, "hmmEnd" : 180, "hmmLength" : 205, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 284, "location-fragments" : [ { "start" : 6, "end" : 256, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-62, "familyName" : "GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1", "score" : 211.7, "model-ac" : "PTHR12192:SF2" } ], "xref" : [ { "name" : "XP_018909872.1 PREDICTED: glutathione-specific gamma-glutamylcyclotransferase 1-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909872.1" } ] },{ "sequence" : "MGSGVDMLACVLDSGCSDSWDPPPDSILEIPPPPMPSFFQSNFTLSPGCSPFSCDWSTGHSVEYVELPHQETQLDETWLIILGSSLVIVLVLSILLTMFLIRCRQLKTLKIPSLSSLNEGGNCEAVLYPASMHGRAFWATLGPHGTMKHVTEPLPFPILKPATKSFENCGFIEAEDYISKVRPRVSSPTRIENPNLPPLNINGSLRRPSYHTIGRQ", "md5" : "00f32cb01e355a38ad153b8b0ccd8c35", "matches" : [ ], "xref" : [ { "name" : "XP_018909927.1 PREDICTED: uncharacterized protein LOC109039051 [Bemisia tabaci]", "id" : "XP_018909927.1" } ] },{ "sequence" : "MSSATSSGNIVVEWLKSLHLGQYAESFLDNGYDDLEICKQVGDPDLDAIGVFNSTHRHRLLQSVRTLREEGAASVYFTLEESAAIQEECLCDSASIRSSRASSGTGKTSDKELPSKNSASAGSSSTGSVQELHAYHDEYEEGKAELVRIPRLQLKSLLKEKLSQDGIQLSNQPYSTMDGQRGYLEGLASRYADMYKTHYRDVLEHLEDLRRRAWGVHLSPSPRTPPGPAPRSPTLTTSLSQPIYVPGKYSPSSCLSDREEDEIYGFAGEAREPVYGVYEKPKPQRRVVINNYQNCLNPRSAYFYEFPPTERSGKKKTTFTRFLKHLKAHRKEKSGSPKHPMHRALTPDRLDEPPGSEYDRLKYFTHGHSGFEETIHRLKLQEAMKKKERFDREHEEILRDIRHGLSREASLGVQLRGEGGGGGGGAGSDDTYMYDDDMIRLATLGHHWYDEPPYESDPEDFLMVAADQHNQRVCYTMKTDKMGLGRSGGKGLKGSKGKGKGVQVNGNGTCNTMGEGGVISLRLAGDISLPPMGIHQRGLILPQAGPYPPTVIPLTRHAHANNRESGDYAASDIQSVCSRLSSLSMETSRSEACEPDLYHRLRPFNNGNDSAISPGSSDCTEEDMVTLHSTQRGSSFLAHRVQGLKFDRSSAQRKHTHRYRCDQHTSSIESLPSGSSTQPLMQGNSSEETGSPSPTIARAKALVDYTPSLYEKDALKFKKGDVIEVISMSTNGLWQGRLGGKQGYFKFTNVQLTNEGNNVHRQHKPLQFKHRSRHRPQTLEQLLETINMKEHMSIFMLNGYEDLESFCAIQEKDLDYLGILDIEQRALILAAVEVMHGYESPDNGDSSGDEYNPESFDQQNNHEHSRSNNLDSNLSETSSASTRTSTKSENSHPMIKTSANNVSSVEVTETQGSNTYLPNIPTKTNQKSSSIVEITSSDLKSNEKVAVVKYICNPSDLTCETNSSIVRNSEENHVIRRNSSNCCTFSEKSSDSGISSSSVSSSAPNQNSVMKIKRKIQTTNNISPGTKAALIESPTRSYVGHFVMDSRKN", "md5" : "f2552d23a63905289727f765f2486252", "matches" : [ { "signature" : { "accession" : "PTHR12301", "name" : "SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 6, "end" : 915, "hmmStart" : 4, "hmmEnd" : 348, "hmmLength" : 402, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 1023, "location-fragments" : [ { "start" : 6, "end" : 915, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-102, "familyName" : "SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED", "score" : 346.4, "model-ac" : "PTHR12301" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 665, "end" : 693, "location-fragments" : [ { "start" : 665, "end" : 693, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF50044", "name" : "SH3-domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036028", "name" : "SH3-like_dom_sf", "description" : "SH3-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 684, "end" : 754, "hmmLength" : 98, "location-fragments" : [ { "start" : 684, "end" : 754, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.4E-14, "model-ac" : "0049867" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 380, "end" : 400, "location-fragments" : [ { "start" : 380, "end" : 400, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "G3DSA:1.10.150.50", "name" : "Transcription Factor", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013761", "name" : "SAM/pointed_sf", "description" : "Sterile alpha motif/pointed domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 768, "end" : 840, "hmmStart" : 8, "hmmEnd" : 71, "hmmLength" : 78, "hmmBounds" : "COMPLETE", "evalue" : 8.1E-14, "score" : 53.4, "envelopeStart" : 768, "envelopeEnd" : 840, "postProcessed" : true, "location-fragments" : [ { "start" : 768, "end" : 840, "dc-status" : "CONTINUOUS" } ] }, { "start" : 2, "end" : 73, "hmmStart" : 12, "hmmEnd" : 73, "hmmLength" : 78, "hmmBounds" : "COMPLETE", "evalue" : 6.4E-20, "score" : 72.9, "envelopeStart" : 2, "envelopeEnd" : 73, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 73, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-37, "score" : 129.5, "model-ac" : "1v38A00" }, { "signature" : { "accession" : "SM00326", "name" : "SH3_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001452", "name" : "SH3_domain", "description" : "SH3 domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 697, "end" : 754, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 58, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-8, "score" : 44.5, "location-fragments" : [ { "start" : 697, "end" : 754, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-8, "score" : 44.5, "model-ac" : "SM00326" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 217, "end" : 237, "location-fragments" : [ { "start" : 217, "end" : 237, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF47769", "name" : "SAM/Pointed domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR013761", "name" : "SAM/pointed_sf", "description" : "Sterile alpha motif/pointed domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 9, "end" : 69, "hmmLength" : 78, "location-fragments" : [ { "start" : 9, "end" : 69, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.48E-18, "model-ac" : "0050037" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 102, "end" : 131, "location-fragments" : [ { "start" : 102, "end" : 131, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF47769", "name" : "SAM/Pointed domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR013761", "name" : "SAM/pointed_sf", "description" : "Sterile alpha motif/pointed domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 771, "end" : 840, "hmmLength" : 78, "location-fragments" : [ { "start" : 771, "end" : 840, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.85E-13, "model-ac" : "0050037" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 102, "end" : 136, "location-fragments" : [ { "start" : 102, "end" : 136, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 839, "end" : 913, "location-fragments" : [ { "start" : 839, "end" : 913, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50105", "name" : "SAM_DOMAIN", "description" : "SAM domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001660", "name" : "SAM", "description" : "Sterile alpha motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 774, "end" : 838, "score" : 8.656, "alignment" : "HRPQTLEQLLETINMKEHMSIFMLnGYEDLESFCAIQEKDLDYLGILDIEQRALILAAVEVMHGY", "location-fragments" : [ { "start" : 774, "end" : 838, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50105" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 654, "end" : 695, "location-fragments" : [ { "start" : 654, "end" : 695, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF07653", "name" : "SH3_2", "description" : "Variant SH3 domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001452", "name" : "SH3_domain", "description" : "SH3 domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 699, "end" : 751, "hmmStart" : 2, "hmmEnd" : 55, "hmmLength" : 57, "hmmBounds" : "INCOMPLETE", "evalue" : 7.6E-10, "score" : 38.4, "envelopeStart" : 698, "envelopeEnd" : 753, "postProcessed" : true, "location-fragments" : [ { "start" : 699, "end" : 751, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-10, "score" : 39.4, "model-ac" : "PF07653" }, { "signature" : { "accession" : "SM00454", "name" : "SAM_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001660", "name" : "SAM", "description" : "Sterile alpha motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 771, "end" : 838, "hmmStart" : 1, "hmmEnd" : 67, "hmmLength" : 67, "hmmBounds" : "COMPLETE", "evalue" : 0.042, "score" : 23.0, "location-fragments" : [ { "start" : 771, "end" : 838, "dc-status" : "CONTINUOUS" } ] }, { "start" : 3, "end" : 70, "hmmStart" : 1, "hmmEnd" : 67, "hmmLength" : 67, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-10, "score" : 50.7, "location-fragments" : [ { "start" : 3, "end" : 70, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-17, "score" : 73.7, "model-ac" : "SM00454" }, { "signature" : { "accession" : "G3DSA:2.30.30.40", "name" : "SH3 Domains", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 693, "end" : 755, "hmmStart" : 3, "hmmEnd" : 61, "hmmLength" : 63, "hmmBounds" : "COMPLETE", "evalue" : 7.8E-23, "score" : 81.6, "envelopeStart" : 693, "envelopeEnd" : 755, "postProcessed" : true, "location-fragments" : [ { "start" : 693, "end" : 755, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-23, "score" : 82.5, "model-ac" : "2keaA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 995, "end" : 1015, "location-fragments" : [ { "start" : 995, "end" : 1015, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50002", "name" : "SH3", "description" : "Src homology 3 (SH3) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001452", "name" : "SH3_domain", "description" : "SH3 domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 694, "end" : 755, "score" : 18.966, "alignment" : "PTIARAKALVDYTpsLYEKDALKFKKGDVIEVISMSTNGLWQGRLG-GKQGYFKFTNVQLTNE", "location-fragments" : [ { "start" : 694, "end" : 755, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50002" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 862, "end" : 913, "location-fragments" : [ { "start" : 862, "end" : 913, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50105", "name" : "SAM_DOMAIN", "description" : "SAM domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001660", "name" : "SAM", "description" : "Sterile alpha motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 70, "score" : 15.582, "alignment" : "SSGNIVVEWLKSLHLGQYAESFLDnGYDDLEICKQVGDPDLDAIGVFNSTHRHRLLQSVRTLREE", "location-fragments" : [ { "start" : 6, "end" : 70, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50105" }, { "signature" : { "accession" : "PF00536", "name" : "SAM_1", "description" : "SAM domain (Sterile alpha motif)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001660", "name" : "SAM", "description" : "Sterile alpha motif domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 775, "end" : 835, "hmmStart" : 4, "hmmEnd" : 63, "hmmLength" : 64, "hmmBounds" : "INCOMPLETE", "evalue" : 2.5E-5, "score" : 24.6, "envelopeStart" : 772, "envelopeEnd" : 836, "postProcessed" : true, "location-fragments" : [ { "start" : 775, "end" : 835, "dc-status" : "CONTINUOUS" } ] }, { "start" : 9, "end" : 68, "hmmStart" : 6, "hmmEnd" : 64, "hmmLength" : 64, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 3.0E-13, "score" : 50.0, "envelopeStart" : 4, "envelopeEnd" : 68, "postProcessed" : true, "location-fragments" : [ { "start" : 9, "end" : 68, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.0E-22, "score" : 77.3, "model-ac" : "PF00536" }, { "signature" : { "accession" : "cd09527", "name" : "SAM_Samd5", "description" : "SAM_Samd5", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 69, "sites" : [ ], "evalue" : 6.82033E-28, "score" : 105.22, "location-fragments" : [ { "start" : 8, "end" : 69, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd09527" } ], "xref" : [ { "name" : "XP_018910500.1 PREDICTED: uncharacterized protein LOC109039472 isoform X1 [Bemisia tabaci]", "id" : "XP_018910500.1" } ] },{ "sequence" : "MGIRGLQTFIEKFCPPNCYYEVSIEQLVEDYKRQTGGKEPVIVVDGSSCLGHIYKGLDWVSGGQYKEYIEKLGKFVHAFKQIGVKLVFYFGGGTVNPKRKEWIKRCFERLERVYQMFDQLSDGLRTTDLHQSLFSLPPGVGTLSQHYLEHIFGCEVYQSVDETDTEIAHYARERKCLAIFGQDSDYLIYEGGTYYLSAQHFNLRTMRTFNYDRRGFAEYLGLETSQLPLFATLAGNDLVSFADLKPFHRFLCRKYTGGGYDVNFKTLFPALARYIQQFPPGEAVFQALPHIAREALNDPRAANVFATSIRSYLSSTKIVKRTTAPNHPHWNAILQRAEELHRSNYSTATVFAIVNGEPFETSTAFEDYRERDLPPFARLLRPMRTRLYGILFHEKPLNLEPQFVLEWCMEGPNSLNEPTRIKPVPPSDPHPGLLALWSDDRTQDLQNARWQLFAHGISSRLNPAKLRHLPQNLVLPTAVMFYIVDNRILATWEIEAMIATVVTLPTVPLERLASLPSDPVDLRAVRIATIYMRSLWSTIILLSACGYPLPPAKTFIHPYFDGKLFQQKYRKAKDKATHAILCGHQVTSIEAFLQVRQVLFESAG", "md5" : "537d951ac0169dcee66a00812757e0e9", "matches" : [ { "signature" : { "accession" : "G3DSA:3.40.50.1010", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 240, "hmmStart" : 1, "hmmEnd" : 232, "hmmLength" : 356, "hmmBounds" : "COMPLETE", "evalue" : 1.0E-9, "score" : 40.0, "envelopeStart" : 2, "envelopeEnd" : 240, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 240, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-10, "score" : 40.5, "model-ac" : "1ul1X00" }, { "signature" : { "accession" : "PTHR15976", "name" : "CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR026784", "name" : "Coact_PPARg", "description" : "Constitutive coactivator of PPAR-gamma", "type" : "FAMILY", "goXRefs" : [ { "name" : "host cell nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0042025" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 317, "hmmStart" : 1, "hmmEnd" : 319, "hmmLength" : 718, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 325, "location-fragments" : [ { "start" : 1, "end" : 317, "dc-status" : "CONTINUOUS" } ] }, { "start" : 320, "end" : 596, "hmmStart" : 403, "hmmEnd" : 678, "hmmLength" : 718, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 314, "envelopeEnd" : 603, "location-fragments" : [ { "start" : 320, "end" : 596, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-114, "familyName" : "CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA", "score" : 384.7, "model-ac" : "PTHR15976" }, { "signature" : { "accession" : "cd18672", "name" : "PIN_FAM120B-like", "description" : "PIN_FAM120B-like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 215, "sites" : [ { "description" : "helical arch", "numLocations" : 15, "siteLocations" : [ { "start" : 98, "end" : 98, "residue" : "K" }, { "start" : 103, "end" : 103, "residue" : "I" }, { "start" : 104, "end" : 104, "residue" : "K" }, { "start" : 132, "end" : 132, "residue" : "S" }, { "start" : 133, "end" : 133, "residue" : "L" }, { "start" : 135, "end" : 135, "residue" : "S" }, { "start" : 101, "end" : 101, "residue" : "E" }, { "start" : 137, "end" : 137, "residue" : "P" }, { "start" : 134, "end" : 134, "residue" : "F" }, { "start" : 99, "end" : 99, "residue" : "R" }, { "start" : 136, "end" : 136, "residue" : "L" }, { "start" : 105, "end" : 105, "residue" : "R" }, { "start" : 97, "end" : 97, "residue" : "P" }, { "start" : 100, "end" : 100, "residue" : "K" }, { "start" : 102, "end" : 102, "residue" : "W" } ] }, { "description" : "metal binding site 2", "numLocations" : 2, "siteLocations" : [ { "start" : 185, "end" : 185, "residue" : "D" }, { "start" : 183, "end" : 183, "residue" : "D" } ] } ], "evalue" : 8.7926E-55, "score" : 183.26, "location-fragments" : [ { "start" : 5, "end" : 215, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd18672" }, { "signature" : { "accession" : "SSF88723", "name" : "PIN domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029060", "name" : "PIN-like_dom_sf", "description" : "PIN-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 220, "hmmLength" : 217, "location-fragments" : [ { "start" : 1, "end" : 220, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.53E-25, "model-ac" : "0049265" } ], "xref" : [ { "name" : "XP_018909871.1 PREDICTED: constitutive coactivator of peroxisome proliferator-activated receptor gamma-like [Bemisia tabaci]", "id" : "XP_018909871.1" }, { "name" : "XP_018909870.1 PREDICTED: constitutive coactivator of peroxisome proliferator-activated receptor gamma-like [Bemisia tabaci]", "id" : "XP_018909870.1" } ] },{ "sequence" : "MLSFQYVLVCGLIAVDFSKAMLRSRIRGMRIVSDETPPQEGALPLDPAADNAALHHLYHQQDPCWNAPHNPGPNHEASRACQRAFNAFNLRPLNLRDRCPFAEEPKCRYFGSPPVKHCSVKKRRPAWCAILGFRHEVVKLSSCARPVFPGFVPAMPPLQVPPVVVFPGL", "md5" : "50a8ce432e51a257497487f33d12adab", "matches" : [ ], "xref" : [ { "name" : "XP_018909969.1 PREDICTED: uncharacterized protein LOC109039083 [Bemisia tabaci]", "id" : "XP_018909969.1" } ] },{ "sequence" : "MNELSVPSLEWDPVTLLFDDAAEFPPAAIVVLNTPIILRPEVVCSLWNRATRRVTVDGGTNHWLRFAEENGKLIENKYPHLITGDMDSIEPDLLSQCQKEKSEVLNTPNQLKTDFHKALDCIASSNNNAVDVVFVLAEHSGRVDQILSNLSTLHQTSKIFKRDVPVFIVASDTVTWVLNPGVQHRIHVADRLIESQSNCGLIPLAGVASHITTTGLKWNLTDQGLEFGNKISSSNTYSGSSIVTVETDTQLVWSMSLGLTKKRD", "md5" : "0b2298dd7883e8b683f5205e83f40dd1", "matches" : [ { "signature" : { "accession" : "PF04265", "name" : "TPK_B1_binding", "description" : "Thiamin pyrophosphokinase, vitamin B1 binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR007373", "name" : "Thiamin_PyroPKinase_B1-bd", "description" : "Thiamin pyrophosphokinase, thiamin-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "thiamine binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030975" }, { "name" : "thiamine diphosphate biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0009229" } ], "pathwayXRefs" : [ { "name" : "Thiamine salvage III", "databaseName" : "MetaCyc", "id" : "PWY-6898" }, { "name" : "Vitamin B1 (thiamin) metabolism", "databaseName" : "Reactome", "id" : "R-HSA-196819" }, { "name" : "Thiamine salvage IV (yeast)", "databaseName" : "MetaCyc", "id" : "PWY-7356" }, { "name" : "Thiamine diphosphate biosynthesis IV (eukaryotes)", "databaseName" : "MetaCyc", "id" : "PWY-6908" }, { "name" : "Thiamine metabolism", "databaseName" : "KEGG", "id" : "00730+2.7.6.2" }, { "name" : "Thiamine diphosphate biosynthesis III (Staphylococcus)", "databaseName" : "MetaCyc", "id" : "PWY-6907" } ] } }, "locations" : [ { "start" : 184, "end" : 251, "hmmStart" : 2, "hmmEnd" : 69, "hmmLength" : 70, "hmmBounds" : "INCOMPLETE", "evalue" : 5.9E-18, "score" : 64.3, "envelopeStart" : 183, "envelopeEnd" : 252, "postProcessed" : true, "location-fragments" : [ { "start" : 184, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-18, "score" : 65.1, "model-ac" : "PF04265" }, { "signature" : { "accession" : "G3DSA:2.60.120.320", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 172, "end" : 255, "hmmStart" : 2, "hmmEnd" : 221, "hmmLength" : 97, "hmmBounds" : "INCOMPLETE", "evalue" : 2.1E-71, "score" : 241.8, "envelopeStart" : 27, "envelopeEnd" : 256, "postProcessed" : true, "location-fragments" : [ { "start" : 172, "end" : 255, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-71, "score" : 242.0, "model-ac" : "1ig3A01" }, { "signature" : { "accession" : "SSF63999", "name" : "Thiamin pyrophosphokinase, catalytic domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036759", "name" : "TPK_catalytic_sf", "description" : "Thiamin pyrophosphokinase, catalytic domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "thiamine diphosphate biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0009229" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "thiamine diphosphokinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004788" } ], "pathwayXRefs" : [ { "name" : "Thiamine salvage IV (yeast)", "databaseName" : "MetaCyc", "id" : "PWY-7356" }, { "name" : "Thiamine diphosphate biosynthesis IV (eukaryotes)", "databaseName" : "MetaCyc", "id" : "PWY-6908" }, { "name" : "Thiamine metabolism", "databaseName" : "KEGG", "id" : "00730+2.7.6.2" }, { "name" : "Thiamine diphosphate biosynthesis III (Staphylococcus)", "databaseName" : "MetaCyc", "id" : "PWY-6907" }, { "name" : "Thiamine salvage III", "databaseName" : "MetaCyc", "id" : "PWY-6898" }, { "name" : "Vitamin B1 (thiamin) metabolism", "databaseName" : "Reactome", "id" : "R-HSA-196819" } ] } }, "locations" : [ { "start" : 23, "end" : 160, "hmmLength" : 221, "location-fragments" : [ { "start" : 23, "end" : 160, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.05E-30, "model-ac" : "0039000" }, { "signature" : { "accession" : "PTHR13622", "name" : "THIAMIN PYROPHOSPHOKINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 26, "end" : 257, "hmmStart" : 16, "hmmEnd" : 236, "hmmLength" : 241, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 6, "envelopeEnd" : 261, "location-fragments" : [ { "start" : 26, "end" : 257, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-56, "familyName" : "THIAMIN PYROPHOSPHOKINASE 1", "score" : 192.3, "model-ac" : "PTHR13622" }, { "signature" : { "accession" : "PTHR13622:SF8", "name" : "THIAMIN PYROPHOSPHOKINASE 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 26, "end" : 257, "hmmStart" : 16, "hmmEnd" : 236, "hmmLength" : 241, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 6, "envelopeEnd" : 261, "location-fragments" : [ { "start" : 26, "end" : 257, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-56, "familyName" : "THIAMIN PYROPHOSPHOKINASE 1", "score" : 192.3, "model-ac" : "PTHR13622:SF8" }, { "signature" : { "accession" : "cd07995", "name" : "TPK", "description" : "TPK", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR007371", "name" : "TPK_catalytic", "description" : "Thiamin pyrophosphokinase, catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "thiamine diphosphate biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0009229" }, { "name" : "thiamine diphosphokinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004788" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Thiamine salvage IV (yeast)", "databaseName" : "MetaCyc", "id" : "PWY-7356" }, { "name" : "Thiamine diphosphate biosynthesis III (Staphylococcus)", "databaseName" : "MetaCyc", "id" : "PWY-6907" }, { "name" : "Thiamine diphosphate biosynthesis IV (eukaryotes)", "databaseName" : "MetaCyc", "id" : "PWY-6908" }, { "name" : "Thiamine metabolism", "databaseName" : "KEGG", "id" : "00730+2.7.6.2" }, { "name" : "Thiamine salvage III", "databaseName" : "MetaCyc", "id" : "PWY-6898" }, { "name" : "Vitamin B1 (thiamin) metabolism", "databaseName" : "Reactome", "id" : "R-HSA-196819" } ] } }, "locations" : [ { "start" : 28, "end" : 231, "sites" : [ { "description" : "dimerization interface", "numLocations" : 26, "siteLocations" : [ { "start" : 111, "end" : 111, "residue" : "L" }, { "start" : 110, "end" : 110, "residue" : "Q" }, { "start" : 148, "end" : 148, "residue" : "S" }, { "start" : 65, "end" : 65, "residue" : "R" }, { "start" : 174, "end" : 174, "residue" : "V" }, { "start" : 142, "end" : 142, "residue" : "R" }, { "start" : 145, "end" : 145, "residue" : "Q" }, { "start" : 143, "end" : 143, "residue" : "V" }, { "start" : 200, "end" : 200, "residue" : "G" }, { "start" : 144, "end" : 144, "residue" : "D" }, { "start" : 205, "end" : 205, "residue" : "A" }, { "start" : 116, "end" : 116, "residue" : "H" }, { "start" : 231, "end" : 231, "residue" : "I" }, { "start" : 146, "end" : 146, "residue" : "I" }, { "start" : 151, "end" : 151, "residue" : "S" }, { "start" : 147, "end" : 147, "residue" : "L" }, { "start" : 62, "end" : 62, "residue" : "H" }, { "start" : 172, "end" : 172, "residue" : "D" }, { "start" : 58, "end" : 58, "residue" : "G" }, { "start" : 112, "end" : 112, "residue" : "K" }, { "start" : 202, "end" : 202, "residue" : "I" }, { "start" : 150, "end" : 150, "residue" : "L" }, { "start" : 198, "end" : 198, "residue" : "N" }, { "start" : 141, "end" : 141, "residue" : "G" }, { "start" : 204, "end" : 204, "residue" : "L" }, { "start" : 139, "end" : 139, "residue" : "H" } ] }, { "description" : "active site", "numLocations" : 23, "siteLocations" : [ { "start" : 149, "end" : 149, "residue" : "N" }, { "start" : 111, "end" : 111, "residue" : "L" }, { "start" : 32, "end" : 32, "residue" : "L" }, { "start" : 110, "end" : 110, "residue" : "Q" }, { "start" : 113, "end" : 113, "residue" : "T" }, { "start" : 57, "end" : 57, "residue" : "D" }, { "start" : 218, "end" : 218, "residue" : "W" }, { "start" : 114, "end" : 114, "residue" : "D" }, { "start" : 87, "end" : 87, "residue" : "D" }, { "start" : 138, "end" : 138, "residue" : "E" }, { "start" : 115, "end" : 115, "residue" : "F" }, { "start" : 88, "end" : 88, "residue" : "S" }, { "start" : 58, "end" : 58, "residue" : "G" }, { "start" : 112, "end" : 112, "residue" : "K" }, { "start" : 142, "end" : 142, "residue" : "R" }, { "start" : 140, "end" : 140, "residue" : "S" }, { "start" : 145, "end" : 145, "residue" : "Q" }, { "start" : 33, "end" : 33, "residue" : "N" }, { "start" : 34, "end" : 34, "residue" : "T" }, { "start" : 141, "end" : 141, "residue" : "G" }, { "start" : 220, "end" : 220, "residue" : "L" }, { "start" : 56, "end" : 56, "residue" : "V" }, { "start" : 85, "end" : 85, "residue" : "D" } ] } ], "evalue" : 1.96021E-36, "score" : 126.506, "location-fragments" : [ { "start" : 28, "end" : 231, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd07995" }, { "signature" : { "accession" : "SM00983", "name" : "TPK_B1_binding_a_2_a", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR007373", "name" : "Thiamin_PyroPKinase_B1-bd", "description" : "Thiamin pyrophosphokinase, thiamin-binding domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "thiamine binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030975" }, { "name" : "thiamine diphosphate biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0009229" } ], "pathwayXRefs" : [ { "name" : "Thiamine salvage III", "databaseName" : "MetaCyc", "id" : "PWY-6898" }, { "name" : "Vitamin B1 (thiamin) metabolism", "databaseName" : "Reactome", "id" : "R-HSA-196819" }, { "name" : "Thiamine salvage IV (yeast)", "databaseName" : "MetaCyc", "id" : "PWY-7356" }, { "name" : "Thiamine diphosphate biosynthesis IV (eukaryotes)", "databaseName" : "MetaCyc", "id" : "PWY-6908" }, { "name" : "Thiamine metabolism", "databaseName" : "KEGG", "id" : "00730+2.7.6.2" }, { "name" : "Thiamine diphosphate biosynthesis III (Staphylococcus)", "databaseName" : "MetaCyc", "id" : "PWY-6907" } ] } }, "locations" : [ { "start" : 181, "end" : 251, "hmmStart" : 1, "hmmEnd" : 74, "hmmLength" : 74, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-12, "score" : 58.2, "location-fragments" : [ { "start" : 181, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-12, "score" : 58.2, "model-ac" : "SM00983" }, { "signature" : { "accession" : "PF04263", "name" : "TPK_catalytic", "description" : "Thiamin pyrophosphokinase, catalytic domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR007371", "name" : "TPK_catalytic", "description" : "Thiamin pyrophosphokinase, catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "thiamine diphosphate biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0009229" }, { "name" : "thiamine diphosphokinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004788" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" } ], "pathwayXRefs" : [ { "name" : "Thiamine salvage IV (yeast)", "databaseName" : "MetaCyc", "id" : "PWY-7356" }, { "name" : "Thiamine diphosphate biosynthesis III (Staphylococcus)", "databaseName" : "MetaCyc", "id" : "PWY-6907" }, { "name" : "Thiamine diphosphate biosynthesis IV (eukaryotes)", "databaseName" : "MetaCyc", "id" : "PWY-6908" }, { "name" : "Thiamine metabolism", "databaseName" : "KEGG", "id" : "00730+2.7.6.2" }, { "name" : "Thiamine salvage III", "databaseName" : "MetaCyc", "id" : "PWY-6898" }, { "name" : "Vitamin B1 (thiamin) metabolism", "databaseName" : "Reactome", "id" : "R-HSA-196819" } ] } }, "locations" : [ { "start" : 45, "end" : 156, "hmmStart" : 3, "hmmEnd" : 112, "hmmLength" : 121, "hmmBounds" : "INCOMPLETE", "evalue" : 1.2E-24, "score" : 86.7, "envelopeStart" : 43, "envelopeEnd" : 167, "postProcessed" : true, "location-fragments" : [ { "start" : 45, "end" : 156, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.0E-25, "score" : 87.2, "model-ac" : "PF04263" }, { "signature" : { "accession" : "SSF63862", "name" : "Thiamin pyrophosphokinase, substrate-binding domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036371", "name" : "TPK_B1-bd_sf", "description" : "Thiamin pyrophosphokinase, thiamin-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "thiamine diphosphate biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0009229" } ], "pathwayXRefs" : [ { "name" : "Vitamin B1 (thiamin) metabolism", "databaseName" : "Reactome", "id" : "R-HSA-196819" }, { "name" : "Thiamine diphosphate biosynthesis IV (eukaryotes)", "databaseName" : "MetaCyc", "id" : "PWY-6908" }, { "name" : "Thiamine diphosphate biosynthesis III (Staphylococcus)", "databaseName" : "MetaCyc", "id" : "PWY-6907" }, { "name" : "Thiamine metabolism", "databaseName" : "KEGG", "id" : "00730+2.7.6.2" }, { "name" : "Thiamine salvage IV (yeast)", "databaseName" : "MetaCyc", "id" : "PWY-7356" }, { "name" : "Thiamine salvage III", "databaseName" : "MetaCyc", "id" : "PWY-6898" } ] } }, "locations" : [ { "start" : 173, "end" : 258, "hmmLength" : 96, "location-fragments" : [ { "start" : 173, "end" : 258, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.19E-22, "model-ac" : "0047356" }, { "signature" : { "accession" : "G3DSA:3.40.50.10240", "name" : "Thiamin pyrophosphokinase", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036759", "name" : "TPK_catalytic_sf", "description" : "Thiamin pyrophosphokinase, catalytic domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "thiamine diphosphate biosynthetic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0009229" }, { "name" : "ATP binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005524" }, { "name" : "thiamine diphosphokinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004788" } ], "pathwayXRefs" : [ { "name" : "Thiamine salvage IV (yeast)", "databaseName" : "MetaCyc", "id" : "PWY-7356" }, { "name" : "Thiamine diphosphate biosynthesis IV (eukaryotes)", "databaseName" : "MetaCyc", "id" : "PWY-6908" }, { "name" : "Thiamine metabolism", "databaseName" : "KEGG", "id" : "00730+2.7.6.2" }, { "name" : "Thiamine diphosphate biosynthesis III (Staphylococcus)", "databaseName" : "MetaCyc", "id" : "PWY-6907" }, { "name" : "Thiamine salvage III", "databaseName" : "MetaCyc", "id" : "PWY-6898" }, { "name" : "Vitamin B1 (thiamin) metabolism", "databaseName" : "Reactome", "id" : "R-HSA-196819" } ] } }, "locations" : [ { "start" : 28, "end" : 171, "hmmStart" : 2, "hmmEnd" : 221, "hmmLength" : 147, "hmmBounds" : "INCOMPLETE", "evalue" : 2.1E-71, "score" : 241.8, "envelopeStart" : 27, "envelopeEnd" : 256, "postProcessed" : true, "location-fragments" : [ { "start" : 28, "end" : 171, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-71, "score" : 242.0, "model-ac" : "1ig3A02" }, { "signature" : { "accession" : "TIGR01378", "name" : "TIGR01378", "description" : "thi_PPkinase: thiamine pyrophosphokinase", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR006282", "name" : "Thi_PPkinase", "description" : "Thiamin pyrophosphokinase", "type" : "FAMILY", "goXRefs" : [ { "name" : "thiamine metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006772" }, { "name" : "thiamine diphosphokinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004788" } ], "pathwayXRefs" : [ { "name" : "Thiamine salvage IV (yeast)", "databaseName" : "MetaCyc", "id" : "PWY-7356" }, { "name" : "Thiamine metabolism", "databaseName" : "KEGG", "id" : "00730+2.7.6.2" }, { "name" : "Thiamine diphosphate biosynthesis III (Staphylococcus)", "databaseName" : "MetaCyc", "id" : "PWY-6907" }, { "name" : "Thiamine diphosphate biosynthesis IV (eukaryotes)", "databaseName" : "MetaCyc", "id" : "PWY-6908" }, { "name" : "Vitamin B1 (thiamin) metabolism", "databaseName" : "Reactome", "id" : "R-HSA-196819" }, { "name" : "Thiamine salvage III", "databaseName" : "MetaCyc", "id" : "PWY-6898" } ] } }, "locations" : [ { "start" : 29, "end" : 255, "hmmStart" : 2, "hmmEnd" : 206, "hmmLength" : 206, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.4E-38, "score" : 130.4, "envelopeStart" : 28, "envelopeEnd" : 255, "postProcessed" : false, "location-fragments" : [ { "start" : 29, "end" : 255, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-38, "score" : 130.6, "model-ac" : "TIGR01378" } ], "xref" : [ { "name" : "XP_018910171.1 PREDICTED: thiamin pyrophosphokinase 1 [Bemisia tabaci]", "id" : "XP_018910171.1" }, { "name" : "XP_018910170.1 PREDICTED: thiamin pyrophosphokinase 1 [Bemisia tabaci]", "id" : "XP_018910170.1" } ] },{ "sequence" : "MSSGSGVRRYSSMWLELTSRLTPCYALGTAIVCGHVAAQHSSPIAIVALPISAHTCLIACMNTPKKPHQLNYWLELLHRVASLSLVAQALGTTMSYMRSDVWIGKILNTNLPLVYPPSALATLSLAMLSLLYSLGLERSSIMRLLMVKCVILLTVCLAFTAVLVPDVTNYKNNIPNHAAHDWSEVVRVGAMLVCSLISTGRVASHVDTIEGRSSVHAGAILLAIVSYTLICMSFSMLINIDLISTDDVAVVKIFAIRGDQGLFLVVYSLTVSILTLTFSELMSPAVHNVVGISSQNYMLPVVLAKEASFTSTHVYAIFFVGCLSAILCLICSMQVLICLVSGTYLLNHVVCVIASLWRRYQPSISISSNYCNGREAEYRPLRTEGDPAPGNSLSSPPGSRTELRGFPREEPGSPGEDQDQHQLISIHADSATDGDSRGSVTSLGSQTRFLRAGPASDFHPHDSNDSGHSSETDIDAAVAQYKEILLIESATNFSSARIPTSETWKKAVASITGIIVCTGILGASIHYSLFFVFFISLLASIFGGLLACQPQRPRVEGEILCPFWLSIANIISCGILLCQIIADIFWITSIWLLIGGGLLWKMRHIRRRTRRRRERIKLISPPLHRTVRTFVTRQRTTNANSESSSLHHQQLSV", "md5" : "ebc04e5dd7dce9e4261ac3d2b25a46d5", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 378, "end" : 430, "location-fragments" : [ { "start" : 378, "end" : 430, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 453, "end" : 472, "location-fragments" : [ { "start" : 453, "end" : 472, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR43243", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 595, "hmmStart" : 37, "hmmEnd" : 497, "hmmLength" : 513, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 599, "location-fragments" : [ { "start" : 14, "end" : 595, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.5E-23, "familyName" : "FAMILY NOT NAMED", "score" : 84.6, "model-ac" : "PTHR43243" } ], "xref" : [ { "name" : "XP_018910504.1 PREDICTED: uncharacterized protein LOC109039475 isoform X2 [Bemisia tabaci]", "id" : "XP_018910504.1" } ] },{ "sequence" : "MASPLLKYSELDFQSYIDRQKSSSALHPVTETNPCSSQDSLAAGHQSSASVNSTQQSSQMDKPTSDQSSQQPSPDTSSTPVNHPSSPRVLFYNDKCIAPFILHIAKNPSADRIPHIHPLQLSSILRRSEVQGVEHVTKVNRSTSQVSFKTRYDANCFLANHKL", "md5" : "12c8f3d15ca13b1d95cbed7fa6488ac2", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 17, "end" : 86, "location-fragments" : [ { "start" : 17, "end" : 86, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910438.1 PREDICTED: uncharacterized protein LOC109039423, partial [Bemisia tabaci]", "id" : "XP_018910438.1" } ] },{ "sequence" : "MRQSSSTKKLAPNVDPVLKMANTISNMRVANSIKGLVSKKKKRYTEDGFNLDLTYITSNLIAMGYPAAKIEGFYRNHIDEVVKFLEEKHRDHYKIYNLCSERSYDINKFQSRVATYPFDDHNPPKMETIQPFCEDVHSWLSAHESNVAAVHCKAGKGRTGVMVCCYMLYCQQFKTAQEALSFYGQKRTTDTKGVTIPSQRRYVGYFASLVNEGLTYKPVTMFIREIIIQPLPTIFSNAHGCLQFQISNSNTRLHSSESIEVKKGSPFIHITMDQCIPLEGDVKVEFSHKPKMMLKEKMFHFWFNTFFIRERLHVPEIANGKNHFDSTHPRYNSHPVDSDTNLFTLRIDKWDLDVAHKDKQNSKYSPDLKVSLILQQVERDTPWSRVQRGINESTEVDSSLDSSSSEESEESEESWESGE", "md5" : "516d2ae740bba6ce68151aa254d7fbc5", "matches" : [ { "signature" : { "accession" : "PF10409", "name" : "PTEN_C2", "description" : "C2 domain of PTEN tumour-suppressor protein", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR014020", "name" : "Tensin_C2-dom", "description" : "Tensin phosphatase, C2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 216, "end" : 375, "hmmStart" : 1, "hmmEnd" : 134, "hmmLength" : 135, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.7E-27, "score" : 94.4, "envelopeStart" : 216, "envelopeEnd" : 376, "postProcessed" : true, "location-fragments" : [ { "start" : 216, "end" : 375, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-27, "score" : 95.1, "model-ac" : "PF10409" }, { "signature" : { "accession" : "PTHR12305", "name" : "PHOSPHATASE WITH HOMOLOGY TO TENSIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 30, "end" : 406, "hmmStart" : 6, "hmmEnd" : 397, "hmmLength" : 421, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 19, "envelopeEnd" : 418, "location-fragments" : [ { "start" : 30, "end" : 406, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-138, "familyName" : "PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN", "score" : 464.3, "model-ac" : "PTHR12305" }, { "signature" : { "accession" : "PF00782", "name" : "DSPc", "description" : "Dual specificity phosphatase, catalytic domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000340", "name" : "Dual-sp_phosphatase_cat-dom", "description" : "Dual specificity phosphatase, catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein tyrosine/serine/threonine phosphatase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0008138" }, { "name" : "dephosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0016311" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 110, "end" : 188, "hmmStart" : 39, "hmmEnd" : 115, "hmmLength" : 133, "hmmBounds" : "INCOMPLETE", "evalue" : 3.9E-7, "score" : 29.9, "envelopeStart" : 94, "envelopeEnd" : 194, "postProcessed" : true, "location-fragments" : [ { "start" : 110, "end" : 188, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-8, "score" : 32.9, "model-ac" : "PF00782" }, { "signature" : { "accession" : "SSF49562", "name" : "C2 domain (Calcium/lipid-binding domain, CaLB)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 217, "end" : 376, "hmmLength" : 141, "location-fragments" : [ { "start" : 217, "end" : 376, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-22, "model-ac" : "0036281" }, { "signature" : { "accession" : "SSF52799", "name" : "(Phosphotyrosine protein) phosphatases II", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029021", "name" : "Prot-tyrosine_phosphatase-like", "description" : "Protein-tyrosine phosphatase-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 48, "end" : 211, "hmmLength" : 174, "location-fragments" : [ { "start" : 48, "end" : 211, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.52E-47, "model-ac" : "0036282" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 383, "end" : 401, "location-fragments" : [ { "start" : 383, "end" : 401, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS51181", "name" : "PPASE_TENSIN", "description" : "Phosphatase tensin-type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR029023", "name" : "Tensin_phosphatase", "description" : "Tensin-type phosphatase domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 42, "end" : 213, "score" : 36.21, "alignment" : "KRYTEDGFNLDLTYITSNLIAMGYPAAKIEGFYRNHIDEVVKFLEEKHRDHYKIYNLC-SERSYDINKFQSRVATYPFDDHNPPKMETIQPFCEDVHSWLSAHESNVAAVHCKAGKGRTGVMVCCYMLYCQQFKTAQEALSFYGQKRTTDT--KGVTIPSQRRYVGYFASLVNEG", "location-fragments" : [ { "start" : 42, "end" : 213, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51181" }, { "signature" : { "accession" : "PS51182", "name" : "C2_TENSIN", "description" : "C2 tensin-type domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR014020", "name" : "Tensin_C2-dom", "description" : "Tensin phosphatase, C2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 218, "end" : 377, "score" : 17.421, "alignment" : "PVTMFIREIIIQPLPTIFSNAHGCLQFQISNSNTRLHSSESIEVKK---GSPFIHITMDQCIPLEGDVKVEFSHKPKMMLK-EKMFHFWFNTFFIRERlhvpeiangknhfdsthprynshpvdsdtnlfTLRIDKWDLDVAHkDKQNSkYSPDLKVSLILQQV", "location-fragments" : [ { "start" : 218, "end" : 377, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51182" }, { "signature" : { "accession" : "G3DSA:3.90.190.10", "name" : "Protein tyrosine phosphatase superfamily", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029021", "name" : "Prot-tyrosine_phosphatase-like", "description" : "Protein-tyrosine phosphatase-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 28, "end" : 213, "hmmStart" : 6, "hmmEnd" : 189, "hmmLength" : 195, "hmmBounds" : "COMPLETE", "evalue" : 8.5E-83, "score" : 279.0, "envelopeStart" : 28, "envelopeEnd" : 213, "postProcessed" : true, "location-fragments" : [ { "start" : 28, "end" : 213, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-83, "score" : 279.6, "model-ac" : "3v0dA01" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 383, "end" : 419, "location-fragments" : [ { "start" : 383, "end" : 419, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:2.60.40.1110", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 216, "end" : 380, "hmmStart" : 1, "hmmEnd" : 139, "hmmLength" : 143, "hmmBounds" : "COMPLETE", "evalue" : 3.0E-44, "score" : 152.2, "envelopeStart" : 216, "envelopeEnd" : 380, "postProcessed" : true, "location-fragments" : [ { "start" : 216, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-44, "score" : 153.3, "model-ac" : "1d5rA02" }, { "signature" : { "accession" : "cd14509", "name" : "PTP_PTEN", "description" : "PTP_PTEN", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 52, "end" : 209, "sites" : [ { "description" : "active site", "numLocations" : 8, "siteLocations" : [ { "start" : 121, "end" : 121, "residue" : "H" }, { "start" : 158, "end" : 158, "residue" : "R" }, { "start" : 199, "end" : 199, "residue" : "Q" }, { "start" : 157, "end" : 157, "residue" : "G" }, { "start" : 120, "end" : 120, "residue" : "D" }, { "start" : 152, "end" : 152, "residue" : "C" }, { "start" : 153, "end" : 153, "residue" : "K" }, { "start" : 154, "end" : 154, "residue" : "A" } ] }, { "description" : "catalytic site", "numLocations" : 2, "siteLocations" : [ { "start" : 158, "end" : 158, "residue" : "R" }, { "start" : 152, "end" : 152, "residue" : "C" } ] } ], "evalue" : 9.93048E-110, "score" : 317.608, "location-fragments" : [ { "start" : 52, "end" : 209, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd14509" }, { "signature" : { "accession" : "SM01326", "name" : "PTEN_C2_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR014020", "name" : "Tensin_C2-dom", "description" : "Tensin phosphatase, C2 domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 216, "end" : 376, "hmmStart" : 1, "hmmEnd" : 170, "hmmLength" : 170, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-37, "score" : 141.1, "location-fragments" : [ { "start" : 216, "end" : 376, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-37, "score" : 141.1, "model-ac" : "SM01326" }, { "signature" : { "accession" : "PS00383", "name" : "TYR_PHOSPHATASE_1", "description" : "Tyrosine specific protein phosphatases active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR016130", "name" : "Tyr_Pase_AS", "description" : "Protein-tyrosine phosphatase, active site", "type" : "ACTIVE_SITE", "goXRefs" : [ { "name" : "dephosphorylation", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0016311" }, { "name" : "protein tyrosine phosphatase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004725" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 150, "end" : 160, "level" : "STRONG", "cigarAlignment" : "3M2I1M2I3M", "alignment" : "VHCkaGkgRTG", "location-fragments" : [ { "start" : 150, "end" : 160, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00383" }, { "signature" : { "accession" : "PTHR12305:SF81", "name" : "PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 30, "end" : 406, "hmmStart" : 6, "hmmEnd" : 397, "hmmLength" : 421, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 19, "envelopeEnd" : 418, "location-fragments" : [ { "start" : 30, "end" : 406, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-138, "familyName" : "PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN", "score" : 464.3, "model-ac" : "PTHR12305:SF81" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 402, "end" : 419, "location-fragments" : [ { "start" : 402, "end" : 419, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909983.1 PREDICTED: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X4 [Bemisia tabaci]", "id" : "XP_018909983.1" } ] },{ "sequence" : "MLSADLNFIIMQAVLLLSVLVSRSNSVEKINHSLFFRASNYNSYQNDPPRQFSRRNEPSTQSTTVGTIDPMEQTVEQILLWLQGKYLSSHRKTRGENQQAVAGAQEPSRVYLPSYPMSQKPRPFKPALEDPGYALNPDPSGTSPPAPTEGVLREGANNGIDAPKPPQAEGATSVAPPNDREPLEPDNGAAGQSPPNPDEQAGTEGAPGVNEFGVDQINPNDVSPVAESPDNSLSANSSAVTADSELNHPPHIHELVVQCAKDQMTISLEFNKVFDGVIYSKGFYSSPECRYVEPNSGKTKFAFSVMLNSCGTQFIDGIMEGKQAYLENVLVLQGEPGIQEVWDTIRAVRCLWEGNLNKALSVALTVGTPNAELVAFSGDTATAKLDIQMGKGPFAPAATGLVKIGELMTLVVTVDGDPGFNVLVRECIARDENPAQSGNMVQLTDSQGCVVKTKLLGRFQTTTNPETNSVIAYAYFNAFKFPDVMDLIIECNVDLCKAACQPCPNPNQSVDPGKRRRREVNNTSFATSSEPVTVAKRLRIYTPDEIEPAASSVVINVGSAADSVCISTINFIISTVVLVSLSIGSSIISATLYLRNHRKSRSAYVVK", "md5" : "7b9a22f9db8bfbccb9fb440ea2aec739", "matches" : [ { "signature" : { "accession" : "PF00100", "name" : "Zona_pellucida", "description" : "Zona pellucida-like domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001507", "name" : "ZP_dom", "description" : "Zona pellucida domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 259, "end" : 503, "hmmStart" : 1, "hmmEnd" : 249, "hmmLength" : 254, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.2E-18, "score" : 67.0, "envelopeStart" : 259, "envelopeEnd" : 507, "postProcessed" : true, "location-fragments" : [ { "start" : 259, "end" : 503, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-18, "score" : 67.6, "model-ac" : "PF00100" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 93, "end" : 243, "location-fragments" : [ { "start" : 93, "end" : 243, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR46560", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 236, "end" : 534, "hmmStart" : 42, "hmmEnd" : 344, "hmmLength" : 547, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 218, "envelopeEnd" : 557, "location-fragments" : [ { "start" : 236, "end" : 534, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-91, "familyName" : "DUSKY-LIKE, ISOFORM A", "score" : 310.3, "model-ac" : "PTHR46560" }, { "signature" : { "accession" : "PS51034", "name" : "ZP_2", "description" : "ZP domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001507", "name" : "ZP_dom", "description" : "Zona pellucida domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 258, "end" : 510, "score" : 33.906, "alignment" : "QCAKDQMTISLEFNKVFDGVI-YSKGFYSSPECRYVEPNSGKtKFAFSVMLNSCGTQFIDgimEGKQAYLENVLVLQGEPGIQEVWDTIRAVRCLWEGNLNKALSvALTVGTPNAELVAFSGDTATAKLDIQMGK---GPFAPAATGLVKiGELMTLVVTVD--GDPGFNVLVRECIARDENPAQSGNMVQLTDSQGCVVKTKLLGRFQTTTNPETNSviAYAYFNAFKFPDVMDLIIECNVDLCKAACQP--CPNPNQSV", "location-fragments" : [ { "start" : 258, "end" : 510, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51034" }, { "signature" : { "accession" : "SM00241", "name" : "zp_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001507", "name" : "ZP_dom", "description" : "Zona pellucida domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 258, "end" : 506, "hmmStart" : 1, "hmmEnd" : 296, "hmmLength" : 296, "hmmBounds" : "COMPLETE", "evalue" : 5.4E-8, "score" : 35.0, "location-fragments" : [ { "start" : 258, "end" : 506, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.4E-8, "score" : 35.0, "model-ac" : "SM00241" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 221, "end" : 243, "location-fragments" : [ { "start" : 221, "end" : 243, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR46560:SF2", "name" : "DUSKY-LIKE, ISOFORM A", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 236, "end" : 534, "hmmStart" : 42, "hmmEnd" : 344, "hmmLength" : 547, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 218, "envelopeEnd" : 557, "location-fragments" : [ { "start" : 236, "end" : 534, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-91, "familyName" : "DUSKY-LIKE, ISOFORM A", "score" : 310.3, "model-ac" : "PTHR46560:SF2" } ], "xref" : [ { "name" : "XP_018909745.1 PREDICTED: uncharacterized protein LOC109038928 [Bemisia tabaci]", "id" : "XP_018909745.1" } ] },{ "sequence" : "MAAGLETSETVDINDVFDSIALSESKLVKQGYSEGYRKGTNDGELSGFHLGYHRGKECGTEIGYYKGVVNTWLTLHDQKICTLSDKILLALSKVKSLIDEFPMKIDDNIDIVELKNNISASYKKACSLLKFDVNCSADFSF", "md5" : "076e8dd6a1eed933e3df1a5ec97bc474", "matches" : [ { "signature" : { "accession" : "PTHR28532:SF1", "name" : "GEO13458P1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 131, "hmmStart" : 4, "hmmEnd" : 126, "hmmLength" : 155, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 6, "envelopeEnd" : 138, "location-fragments" : [ { "start" : 9, "end" : 131, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-22, "familyName" : "GEO13458P1", "score" : 81.9, "model-ac" : "PTHR28532:SF1" }, { "signature" : { "accession" : "PTHR28532", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 131, "hmmStart" : 4, "hmmEnd" : 126, "hmmLength" : 155, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 6, "envelopeEnd" : 138, "location-fragments" : [ { "start" : 9, "end" : 131, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.1E-22, "familyName" : "GEO13458P1", "score" : 81.9, "model-ac" : "PTHR28532" }, { "signature" : { "accession" : "PF09811", "name" : "Yae1_N", "description" : "Essential protein Yae1, N terminal", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR019191", "name" : "Essential_protein_Yae1_N", "description" : "Essential protein Yae1, N-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 31, "end" : 69, "hmmStart" : 1, "hmmEnd" : 39, "hmmLength" : 39, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-7, "score" : 30.5, "envelopeStart" : 31, "envelopeEnd" : 69, "postProcessed" : true, "location-fragments" : [ { "start" : 31, "end" : 69, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-7, "score" : 31.0, "model-ac" : "PF09811" } ], "xref" : [ { "name" : "XP_018910527.1 PREDICTED: oral cancer-overexpressed protein 1 [Bemisia tabaci]", "id" : "XP_018910527.1" } ] },{ "sequence" : "MIILNNFIKELYFKNMYKFALYLAIFGYATNLSEALALKNQALDWWQRGVFYQVYPRSFRDSNADGIGDLRGIAEKVWYLKDLGVTAVWLNPIFESPNLDLGYDISNYTKIDPVYGTLEDLEYLKNALHKAGLRLLLDFVPNHTSDQHPWFQKSIKKIEPYTNYYVWKDAKFNAKGERMPPTNWISEFGGYTWSWNEERQQYYLHLFHYKQPDLNYNSKELVKEMTDVIRFWLDRGIDGLRMDAVTFLYEDPQYRDQELLSPDLDPWDFKSYNRCHTMDQPATYRLITKFREIFDAYSKKDGETKVMITEAYTSLDKTMEYYKFGDKPGAHMPFNFLFITSLDGRSPAKEYQRIIESWMSGMPEGQWPNWVIGNHDNHRLASRYGTDLVDGLNMIGLLLPGTGNTYYGDEIGMEDTNVRFDEGVDPQACEFGKEKYRLVTRDPERTPFQWDTTLNSGFSASLKTWLPVNSNFWRLNLKAQVQSEGNSHYKVYKRLIDVRKTDTMLYGALETHVLSKWVFSFARRQNGSDTYVVVVNLGSETAPVDLSAFMNDIPDTLTVHTSSINSQHQPGDKVAINEFMMRPKSSLLLTTASEVPPPSYKTITSSSSKLNVPIGTLILFLFCKYLV", "md5" : "1b2c0af54c1435d3a4c167e5810edb28", "matches" : [ { "signature" : { "accession" : "G3DSA:3.20.20.80", "name" : "Glycosidases", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 45, "end" : 500, "hmmStart" : 1, "hmmEnd" : 451, "hmmLength" : 394, "hmmBounds" : "INCOMPLETE", "evalue" : 4.4E-160, "score" : 535.6, "envelopeStart" : 45, "envelopeEnd" : 501, "postProcessed" : true, "location-fragments" : [ { "start" : 219, "end" : 500, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 45, "end" : 144, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 3.8E-160, "score" : 535.8, "model-ac" : "3wy1A01" }, { "signature" : { "accession" : "G3DSA:3.90.400.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 145, "end" : 218, "hmmStart" : 1, "hmmEnd" : 451, "hmmLength" : 452, "hmmBounds" : "INCOMPLETE", "evalue" : 4.4E-160, "score" : 535.6, "envelopeStart" : 45, "envelopeEnd" : 501, "postProcessed" : true, "location-fragments" : [ { "start" : 145, "end" : 218, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.8E-160, "score" : 535.8, "model-ac" : "3wy1A02" }, { "signature" : { "accession" : "G3DSA:2.60.40.1180", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013780", "name" : "Glyco_hydro_b", "description" : "Glycosyl hydrolase, all-beta", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 509, "end" : 593, "hmmStart" : 8, "hmmEnd" : 86, "hmmLength" : 91, "hmmBounds" : "COMPLETE", "evalue" : 2.0E-5, "score" : 26.6, "envelopeStart" : 509, "envelopeEnd" : 593, "postProcessed" : true, "location-fragments" : [ { "start" : 509, "end" : 593, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-5, "score" : 27.6, "model-ac" : "2dh2A02" }, { "signature" : { "accession" : "PTHR10357", "name" : "ALPHA-AMYLASE FAMILY MEMBER", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 40, "end" : 599, "hmmStart" : 28, "hmmEnd" : 589, "hmmLength" : 605, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 614, "location-fragments" : [ { "start" : 40, "end" : 599, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-213, "familyName" : "FI17312P1-RELATED", "score" : 711.2, "model-ac" : "PTHR10357" }, { "signature" : { "accession" : "SSF51445", "name" : "(Trans)glycosidases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR017853", "name" : "Glycoside_hydrolase_SF", "description" : "Glycoside hydrolase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 44, "end" : 502, "hmmLength" : 479, "location-fragments" : [ { "start" : 44, "end" : 502, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.29E-120, "model-ac" : "0044469" }, { "signature" : { "accession" : "SM00642", "name" : "aamy", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR006047", "name" : "Glyco_hydro_13_cat_dom", "description" : "Glycosyl hydrolase, family 13, catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 53, "end" : 445, "hmmStart" : 1, "hmmEnd" : 547, "hmmLength" : 547, "hmmBounds" : "COMPLETE", "evalue" : 3.7E-113, "score" : 391.9, "location-fragments" : [ { "start" : 53, "end" : 445, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.7E-113, "score" : 391.9, "model-ac" : "SM00642" }, { "signature" : { "accession" : "PTHR10357:SF177", "name" : "FI17312P1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 40, "end" : 599, "hmmStart" : 28, "hmmEnd" : 589, "hmmLength" : 605, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 15, "envelopeEnd" : 614, "location-fragments" : [ { "start" : 40, "end" : 599, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.8E-213, "familyName" : "FI17312P1-RELATED", "score" : 711.2, "model-ac" : "PTHR10357:SF177" }, { "signature" : { "accession" : "cd11328", "name" : "AmyAc_maltase", "description" : "AmyAc_maltase", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 43, "end" : 510, "sites" : [ { "description" : "active site", "numLocations" : 11, "siteLocations" : [ { "start" : 103, "end" : 103, "residue" : "Y" }, { "start" : 211, "end" : 211, "residue" : "Q" }, { "start" : 243, "end" : 243, "residue" : "D" }, { "start" : 310, "end" : 310, "residue" : "E" }, { "start" : 100, "end" : 100, "residue" : "D" }, { "start" : 207, "end" : 207, "residue" : "F" }, { "start" : 140, "end" : 140, "residue" : "V" }, { "start" : 143, "end" : 143, "residue" : "H" }, { "start" : 188, "end" : 188, "residue" : "F" }, { "start" : 375, "end" : 375, "residue" : "H" }, { "start" : 376, "end" : 376, "residue" : "D" } ] }, { "description" : "catalytic site", "numLocations" : 3, "siteLocations" : [ { "start" : 243, "end" : 243, "residue" : "D" }, { "start" : 310, "end" : 310, "residue" : "E" }, { "start" : 376, "end" : 376, "residue" : "D" } ] } ], "evalue" : 0.0, "score" : 750.6, "location-fragments" : [ { "start" : 43, "end" : 510, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd11328" }, { "signature" : { "accession" : "PF00128", "name" : "Alpha-amylase", "description" : "Alpha amylase, catalytic domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR006047", "name" : "Glyco_hydro_13_cat_dom", "description" : "Glycosyl hydrolase, family 13, catalytic domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 68, "end" : 417, "hmmStart" : 1, "hmmEnd" : 334, "hmmLength" : 336, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.7E-97, "score" : 327.0, "envelopeStart" : 68, "envelopeEnd" : 425, "postProcessed" : true, "location-fragments" : [ { "start" : 68, "end" : 417, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-97, "score" : 327.5, "model-ac" : "PF00128" } ], "xref" : [ { "name" : "XP_018910471.1 PREDICTED: alpha-glucosidase-like [Bemisia tabaci]", "id" : "XP_018910471.1" } ] },{ "sequence" : "MNRDKNNRSFMERSGDDDADDSDDASNTVRKKASACCVNTCSSDANINNHSENLELNVCSGETGTGNSSNNPHTAENKHYPTNKIIEVSKSSNNETCPVASCVFFPNLVDTPPPKKERIEAPTEENALLRRSHDAAHKKAESMEFFSSLVANLNLRRRNFPSQESRIGINYFPSELSERIENEIEDDTSDGDGVSMLSRPVRFSRSRTSLLSQKFAAIAPRPCSRLEIIFEKSQRLQNEEIVDNLLSSLDILLPSCKPEISEENDNSLKVIIDSNKKINDHTKWNPSQIKEDKKVDVSQCDSAVKQAPMYPGGGGNKMQGTYRFPTGDSNSGAGSQPNYSSNMNNSGPGFRGPRPGFSSLLSNVSSVDLSPFRGGAPIRFRLGTTPRMNPKKVQDKVPSAASQASSSPQSDSPTKEDEDVDLYSDIEHDPHEDVDEDKNFGTLEPPPEPPALLMGLGDEGTDEEEALVIDDKGADVYDPAEPCDDSNDASDSRNDEPVEAMNLTKPSSGYLHSPTYNDIVAQHDDKIGNGSSYDGVPKMMEPPPIPDALKIMEPPPFPSELLSKEIQGDDDEECPNFSLYSSASMNLVKKSSSVLDIPIPAQSNLDIPIPTQPNLDIPMPGPPNLDIPVPGSPTVANIPVPNSGSKTEKSTKEKKKKKKKKPLMYSVPTLEETILKERLGNYSSEDNTDSDDSEEKVKIIIPKRKKKASKKSKKKLAEAEKVDEMNDDAFENVNGEKKPEEKEEEEKENEEEKIVEVNVELDDNDEQSNFDDVSESKAPEKEGGDETEGDTQDEVESKIVSESSMDSIRPQVDEQTIDDNQETVSSLDNSDVSKLPDDKSDSSKMAILSNEGKEKLYDGEDESSIQGDILDIEAEANLQDATSIPDEQDDIKSSTPSKSNAQKSDGLVDITDEEMSEYDHSREEPSNKLDSLNTEAISEDEASIVDGNKESEQSCPTLPGLEGLQTDPISDSDGNAFDESNYSADKESEYDGGKRRKKKKKVQKEKEQSASENEDANVSKSKEKRNSADFEEGEIVDDKPKSSSKKDKKKKAKDKEAKENLDRSKSDHEKDKEKDKKQKKSKDGKSKDKDSVLQSSENKSSEENKEGSPSQSAADVNWKKLSKSTKDRNYRDGKGKPTNDKGRKSPERSTPKEREKKKEKRKELERYNVRKVLGEKVRLIGKDDFGRDLSLNRSMSRSRSRSRNRKGKGKSRSTSRSPYRSPVRSRAARSRSRSRSRSRSRRRLGRKRSRSKNRTLRRSYDRSRSKSRGRSRDRLRKKRASSRDRLRRSLSKGRVSRKKKKSVERRRNRSYSPEYSPARKRRSNSRYSFSPSWSSYSYSPSPGYSRSYSLSPSPSWSPENRALVYNREKNRPPKNITVIVPNEDANAKKKGKKRLSKKNKENEKRRKKRDRSPAPSKEVFTSGDNILVSVNFSNNKNDGTMGSLLHTNEYSTARRRSVEAEPPAKKSKETKNKEKKSKNSTPKKSRSARAVAVNEAAKNAKPIAVIDLNMSPFREETPSPKEVIVVTDSDLEAEQIEKEAPTSNRKVSRKSGSGRERDRDRDRDRDRDRDRNRDRDLGPPTSVSQPESPINDFMNTSAGGPKTPPEPRVAFSISSKQPQMRTMINPLMDGDEEEEQMEEANNEAEMNEIFSKGPNTPPEPPPDTNTPASPPTTPYDPFDPTKSRSPSPELGEQTSTPVNLRDGNKAHDTLSPNVLESNDLDSRNKTSPQVPDENKKTPDNLRSLQKDTIPILESPKQSSPNVSGVNDSNDGVVMKILGQAKIDLTTYKSPEPIAGTPRSTQLTPKPITPSKQSILSVSRAPAPASANKIPVYTPSITLNGEKMDEAPMDISGDSPYSPEPFEAEDLFEPPPISPPRTANKLPMPPIIRSSLTKANKSKFDALFGSLTRKTNTKQLKPVPYTPKPIIPSIKGTKAQKQMKGSKKEVGVKMDEDQLKILDDLPSSAVEMQYLKKLNRQERVVEEVKLVLKPHYAKKHIAKEDYKEILRRAVPKICHNRSGEINPQKIQMLIEAYVRKFQAKTSKKKGGAETTTNNTSNLSKRSKATRS", "md5" : "18e3446f668851ed2505f2376ff3d507", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 613, "end" : 629, "location-fragments" : [ { "start" : 613, "end" : 629, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1226, "end" : 1255, "location-fragments" : [ { "start" : 1226, "end" : 1255, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1710, "end" : 1725, "location-fragments" : [ { "start" : 1710, "end" : 1725, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1004, "end" : 1104, "location-fragments" : [ { "start" : 1004, "end" : 1104, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1864, "end" : 1881, "location-fragments" : [ { "start" : 1864, "end" : 1881, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 817, "end" : 831, "location-fragments" : [ { "start" : 817, "end" : 831, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 378, "end" : 574, "location-fragments" : [ { "start" : 378, "end" : 574, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 770, "end" : 785, "location-fragments" : [ { "start" : 770, "end" : 785, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 396, "end" : 411, "location-fragments" : [ { "start" : 396, "end" : 411, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 740, "end" : 767, "location-fragments" : [ { "start" : 740, "end" : 767, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1838, "end" : 1889, "location-fragments" : [ { "start" : 1838, "end" : 1889, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 539, "end" : 553, "location-fragments" : [ { "start" : 539, "end" : 553, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 412, "end" : 442, "location-fragments" : [ { "start" : 412, "end" : 442, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1269, "end" : 1306, "location-fragments" : [ { "start" : 1269, "end" : 1306, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1391, "end" : 1405, "location-fragments" : [ { "start" : 1391, "end" : 1405, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2043, "end" : 2066, "location-fragments" : [ { "start" : 2043, "end" : 2066, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1439, "end" : 1768, "location-fragments" : [ { "start" : 1439, "end" : 1768, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 26, "location-fragments" : [ { "start" : 1, "end" : 26, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1726, "end" : 1742, "location-fragments" : [ { "start" : 1726, "end" : 1742, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1120, "end" : 1190, "location-fragments" : [ { "start" : 1120, "end" : 1190, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1792, "end" : 1820, "location-fragments" : [ { "start" : 1792, "end" : 1820, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1105, "end" : 1119, "location-fragments" : [ { "start" : 1105, "end" : 1119, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1364, "end" : 1422, "location-fragments" : [ { "start" : 1364, "end" : 1422, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1686, "end" : 1702, "location-fragments" : [ { "start" : 1686, "end" : 1702, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 678, "end" : 701, "location-fragments" : [ { "start" : 678, "end" : 701, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1452, "end" : 1476, "location-fragments" : [ { "start" : 1452, "end" : 1476, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1750, "end" : 1768, "location-fragments" : [ { "start" : 1750, "end" : 1768, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1627, "end" : 1647, "location-fragments" : [ { "start" : 1627, "end" : 1647, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1198, "end" : 1213, "location-fragments" : [ { "start" : 1198, "end" : 1213, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12618", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1343, "end" : 2045, "hmmStart" : 913, "hmmEnd" : 1449, "hmmLength" : 1450, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1331, "envelopeEnd" : 2046, "location-fragments" : [ { "start" : 1343, "end" : 2045, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-43, "familyName" : "FAMILY NOT NAMED", "score" : 150.4, "model-ac" : "PTHR12618" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1654, "end" : 1677, "location-fragments" : [ { "start" : 1654, "end" : 1677, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 15, "location-fragments" : [ { "start" : 1, "end" : 15, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 980, "end" : 994, "location-fragments" : [ { "start" : 980, "end" : 994, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 713, "end" : 744, "location-fragments" : [ { "start" : 713, "end" : 744, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1527, "end" : 1577, "location-fragments" : [ { "start" : 1527, "end" : 1577, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1058, "end" : 1078, "location-fragments" : [ { "start" : 1058, "end" : 1078, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 609, "end" : 1323, "location-fragments" : [ { "start" : 609, "end" : 1323, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1578, "end" : 1598, "location-fragments" : [ { "start" : 1578, "end" : 1598, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 745, "end" : 769, "location-fragments" : [ { "start" : 745, "end" : 769, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 322, "end" : 348, "location-fragments" : [ { "start" : 322, "end" : 348, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1307, "end" : 1321, "location-fragments" : [ { "start" : 1307, "end" : 1321, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2040, "end" : 2066, "location-fragments" : [ { "start" : 2040, "end" : 2066, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1788, "end" : 1821, "location-fragments" : [ { "start" : 1788, "end" : 1821, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 907, "end" : 929, "location-fragments" : [ { "start" : 907, "end" : 929, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 310, "end" : 354, "location-fragments" : [ { "start" : 310, "end" : 354, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910052.1 PREDICTED: serine/arginine repetitive matrix protein 2-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910052.1" } ] },{ "sequence" : "MSSNVENLSPQIIRQIAKEMHDLAHDPPEGIKVTLNEQDVTDIQACIEGPADTPYAGGVFRVKLSLGKDFPQAPPKAFFLTKIFHPNVAINGEICVNTLKRDWKPDLGIKHILLTVKCLLIVPNAESALNEEAGKLLLEHYEDYSQRAKMMTEIHALSTKVPKMGLETSTSDGPLAKKHAGLKVPADKKKILKDKKRTLKRL", "md5" : "b005d2d3ba3dcb8db5f08867caf76a27", "matches" : [ { "signature" : { "accession" : "cd00195", "name" : "UBCc", "description" : "UBCc", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000608", "name" : "UBQ-conjugat_E2", "description" : "Ubiquitin-conjugating enzyme E2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" } ] } }, "locations" : [ { "start" : 13, "end" : 152, "sites" : [ { "description" : "E3 interaction residues", "numLocations" : 5, "siteLocations" : [ { "start" : 72, "end" : 72, "residue" : "Q" }, { "start" : 14, "end" : 14, "residue" : "R" }, { "start" : 106, "end" : 106, "residue" : "D" }, { "start" : 105, "end" : 105, "residue" : "P" }, { "start" : 71, "end" : 71, "residue" : "P" } ] }, { "description" : "Ub thioester intermediate interaction residues", "numLocations" : 21, "siteLocations" : [ { "start" : 82, "end" : 82, "residue" : "K" }, { "start" : 118, "end" : 118, "residue" : "C" }, { "start" : 104, "end" : 104, "residue" : "K" }, { "start" : 122, "end" : 122, "residue" : "V" }, { "start" : 99, "end" : 99, "residue" : "L" }, { "start" : 95, "end" : 95, "residue" : "C" }, { "start" : 112, "end" : 112, "residue" : "I" }, { "start" : 96, "end" : 96, "residue" : "V" }, { "start" : 115, "end" : 115, "residue" : "T" }, { "start" : 126, "end" : 126, "residue" : "E" }, { "start" : 103, "end" : 103, "residue" : "W" }, { "start" : 90, "end" : 90, "residue" : "I" }, { "start" : 127, "end" : 127, "residue" : "S" }, { "start" : 83, "end" : 83, "residue" : "I" }, { "start" : 107, "end" : 107, "residue" : "L" }, { "start" : 98, "end" : 98, "residue" : "T" }, { "start" : 87, "end" : 87, "residue" : "N" }, { "start" : 88, "end" : 88, "residue" : "V" }, { "start" : 121, "end" : 121, "residue" : "I" }, { "start" : 124, "end" : 124, "residue" : "N" }, { "start" : 94, "end" : 94, "residue" : "I" } ] }, { "description" : "active site cysteine", "numLocations" : 1, "siteLocations" : [ { "start" : 95, "end" : 95, "residue" : "C" } ] } ], "evalue" : 1.00583E-48, "score" : 153.512, "location-fragments" : [ { "start" : 13, "end" : 152, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00195" }, { "signature" : { "accession" : "G3DSA:3.10.110.10", "name" : "Ubiquitin Conjugating Enzyme", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR016135", "name" : "UBQ-conjugating_enzyme/RWD", "description" : "Ubiquitin-conjugating enzyme/RWD-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 156, "hmmStart" : 4, "hmmEnd" : 157, "hmmLength" : 158, "hmmBounds" : "COMPLETE", "evalue" : 7.5E-56, "score" : 189.9, "envelopeStart" : 1, "envelopeEnd" : 156, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 156, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.3E-56, "score" : 190.2, "model-ac" : "1zdnA00" }, { "signature" : { "accession" : "SM00212", "name" : "ubc_7", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 14, "end" : 157, "hmmStart" : 1, "hmmEnd" : 144, "hmmLength" : 144, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-41, "score" : 153.6, "location-fragments" : [ { "start" : 14, "end" : 157, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.1E-41, "score" : 153.6, "model-ac" : "SM00212" }, { "signature" : { "accession" : "PTHR24068", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 164, "hmmStart" : 4, "hmmEnd" : 163, "hmmLength" : 224, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 200, "location-fragments" : [ { "start" : 5, "end" : 164, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-83, "familyName" : "UBIQUITIN-CONJUGATING ENZYME E2 S", "score" : 280.8, "model-ac" : "PTHR24068" }, { "signature" : { "accession" : "PTHR24068:SF126", "name" : "UBIQUITIN-CONJUGATING ENZYME E2 S", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 164, "hmmStart" : 4, "hmmEnd" : 163, "hmmLength" : 224, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 200, "location-fragments" : [ { "start" : 5, "end" : 164, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-83, "familyName" : "UBIQUITIN-CONJUGATING ENZYME E2 S", "score" : 280.8, "model-ac" : "PTHR24068:SF126" }, { "signature" : { "accession" : "PS00183", "name" : "UBIQUITIN_CONJUGAT_1", "description" : "Ubiquitin-conjugating enzymes active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR023313", "name" : "UBQ-conjugating_AS", "description" : "Ubiquitin-conjugating enzyme, active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" }, { "name" : "Protein ubiquitination", "databaseName" : "MetaCyc", "id" : "PWY-7511" } ] } }, "locations" : [ { "start" : 84, "end" : 99, "level" : "STRONG", "cigarAlignment" : "5M3I1M1I3M2I1M", "alignment" : "FHPNVainGeICVntL", "location-fragments" : [ { "start" : 84, "end" : 99, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00183" }, { "signature" : { "accession" : "PF00179", "name" : "UQ_con", "description" : "Ubiquitin-conjugating enzyme", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000608", "name" : "UBQ-conjugat_E2", "description" : "Ubiquitin-conjugating enzyme E2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" } ] } }, "locations" : [ { "start" : 16, "end" : 150, "hmmStart" : 2, "hmmEnd" : 138, "hmmLength" : 140, "hmmBounds" : "INCOMPLETE", "evalue" : 1.0E-37, "score" : 128.9, "envelopeStart" : 15, "envelopeEnd" : 152, "postProcessed" : true, "location-fragments" : [ { "start" : 16, "end" : 150, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-38, "score" : 129.3, "model-ac" : "PF00179" }, { "signature" : { "accession" : "PS50127", "name" : "UBIQUITIN_CONJUGAT_2", "description" : "Ubiquitin-conjugating enzymes family profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000608", "name" : "UBQ-conjugat_E2", "description" : "Ubiquitin-conjugating enzyme E2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" } ] } }, "locations" : [ { "start" : 14, "end" : 146, "score" : 33.232, "alignment" : "RQIAKEMHDLAHDPPEGIKVTLNEQ-DVTDIQACIEGPADTPYAGGVFRVKLSLGKDFPQAPPKAFFLTKIFHPNVAINGEICVNTLKRDWKPDLGIKHILLTVKCLLIVPNAESALNEEAGKLLLEHYEDYSQ", "location-fragments" : [ { "start" : 14, "end" : 146, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50127" }, { "signature" : { "accession" : "SSF54495", "name" : "UBC-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016135", "name" : "UBQ-conjugating_enzyme/RWD", "description" : "Ubiquitin-conjugating enzyme/RWD-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 3, "end" : 157, "hmmLength" : 176, "location-fragments" : [ { "start" : 3, "end" : 157, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.84E-48, "model-ac" : "0054300" } ], "xref" : [ { "name" : "XP_018909800.1 PREDICTED: ubiquitin-conjugating enzyme E2 S [Bemisia tabaci]", "id" : "XP_018909800.1" } ] },{ "sequence" : "MLKLFRRGTSRSLVAVLLIASVTTLCVYYANNGGPIEKVGDGRNGGGGGGGGVGGGGGDASAAGGDYGDREEGIPEEWGPAQETKPGWLESDSSSDPSICPRVPEAVADIDTVKQFANFEFQPYWMKSREYWDNSFEERYRVRKQKWSKLPLKVILVPHSHNDPGWLKTFEGYYHSTTKHILNYMAEKLTSMPNMTFIWSEVSFLAQWWDSVHPTKKKQVLKLLDQGRLEITTGGWVMVDEATSHVFAMVDQLIEGHQWLRNNLGVELKTGWAVDPFGHGSTVPYLLKAAGLSGGAVIQRIHYAWKQWLAKEESGDFIWRQNWDADGHTDFLVHNQPFDIYSIKHSCGPHPQVCLNFDFRRIPGEYTEFSIRAVPIDKKNVRQKAELLLEQYGRAGSLVPHNVVMMPLGDDFRYNYDVEWEQQYRNYVQLFDYINAHNTTYNAEFRFGTPADYFKLVKERLKLLDIDPKTLKGDFFVYSDIFTEGRPAYWSGYFTTRPFFKILSRELEHNLRSAEILYTLSLNYMKMLGISASVKILERDFEKLSRARQNLALFQHHDAITGTSKGFVMHDYALKLFESLQEASFVQSYSVQNLLLAFQSKKASSVSPSLRFVVPSAERETYERLAEDVLLAFSPKSTRRKVLVFNSLAQVRYDVIKLKISDPNVKVSDVTGKPVVSQISPYLNITDSDMSGSSVITSRFLYELVFIVEVPPLSLSVFVVESTTKAEAKGSISTLYCKRCSQEHIFPIKVIQPGDVQLENHHLKLLFDAATGFLKATTQKTTGKVTQSSIQFAAYNSAQFHSGAYLFMPDPSTNEIERDVLAEYTDKQRIVIVSGPIYSELVVVYGSFLQHRTRLYHSKSPLGHGIYVENIVDFDKPPKNRETELFMRIVSDISNGDTPEFYTDANGFSMQKRVKVDRIGIEGNYFPITTCAYIQDASRRLSILVNHAQGTAAWEPGWLEVMLDRRTLYDDARGMGEGVVDNKRTLMKFWVLLEDVTSPTHLTTPSLSSNYLSNSLLYPSNVFLLDTSNMDVETNLVFISKPFPCDVHLMNLRTLTDPVYGSQFPSNSALMILHRQGFTCSVASNIQLSKCNFRASTEKSALYADTNFTHLKLKSITQTSLTGMQQLSGELESFNQLNLSPMDILTVNLTFSL", "md5" : "bc6432b86889fb39445ad1adbacb3e59", "matches" : [ { "signature" : { "accession" : "G3DSA:3.20.110.10", "name" : "Glycoside hydrolase 38", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR027291", "name" : "Glyco_hydro_38_N_sf", "description" : "Glycoside hydrolase 38, N-terminal domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 102, "end" : 481, "hmmStart" : 11, "hmmEnd" : 380, "hmmLength" : 382, "hmmBounds" : "COMPLETE", "evalue" : 2.8E-136, "score" : 456.5, "envelopeStart" : 102, "envelopeEnd" : 481, "postProcessed" : true, "location-fragments" : [ { "start" : 102, "end" : 481, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-136, "score" : 457.1, "model-ac" : "3bvxA01" }, { "signature" : { "accession" : "SSF88713", "name" : "Glycoside hydrolase/deacetylase", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011330", "name" : "Glyco_hydro/deAcase_b/a-brl", "description" : "Glycoside hydrolase/deacetylase, beta/alpha-barrel", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" }, { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 108, "end" : 480, "hmmLength" : 381, "location-fragments" : [ { "start" : 108, "end" : 480, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.42E-105, "model-ac" : "0038723" }, { "signature" : { "accession" : "PTHR11607:SF57", "name" : "ALPHA-MANNOSIDASE 2X", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 115, "end" : 1151, "hmmStart" : 100, "hmmEnd" : 1076, "hmmLength" : 1076, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 13, "envelopeEnd" : 1151, "location-fragments" : [ { "start" : 115, "end" : 1151, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "ALPHA-MANNOSIDASE 2X", "score" : 1245.1, "model-ac" : "PTHR11607:SF57" }, { "signature" : { "accession" : "PF09261", "name" : "Alpha-mann_mid", "description" : "Alpha mannosidase middle domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR015341", "name" : "Glyco_hydro_38_cen", "description" : "Glycoside hydrolase family 38, central domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "alpha-mannosidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004559" }, { "name" : "mannose metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006013" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 488, "end" : 594, "hmmStart" : 1, "hmmEnd" : 96, "hmmLength" : 96, "hmmBounds" : "COMPLETE", "evalue" : 4.1E-22, "score" : 78.1, "envelopeStart" : 488, "envelopeEnd" : 594, "postProcessed" : true, "location-fragments" : [ { "start" : 488, "end" : 594, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-22, "score" : 79.8, "model-ac" : "PF09261" }, { "signature" : { "accession" : "PF07748", "name" : "Glyco_hydro_38C", "description" : "Glycosyl hydrolases family 38 C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR011682", "name" : "Glyco_hydro_38_C", "description" : "Glycosyl hydrolase family 38, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "mannose metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006013" }, { "name" : "alpha-mannosidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004559" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 758, "end" : 973, "hmmStart" : 1, "hmmEnd" : 214, "hmmLength" : 214, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-46, "score" : 159.5, "envelopeStart" : 758, "envelopeEnd" : 973, "postProcessed" : true, "location-fragments" : [ { "start" : 758, "end" : 973, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.0E-47, "score" : 160.2, "model-ac" : "PF07748" }, { "signature" : { "accession" : "G3DSA:2.60.40.1180", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR013780", "name" : "Glyco_hydro_b", "description" : "Glycosyl hydrolase, all-beta", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 627, "end" : 723, "hmmStart" : 14, "hmmEnd" : 86, "hmmLength" : 89, "hmmBounds" : "COMPLETE", "evalue" : 9.6E-12, "score" : 46.9, "envelopeStart" : 627, "envelopeEnd" : 723, "postProcessed" : true, "location-fragments" : [ { "start" : 627, "end" : 723, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.6E-12, "score" : 48.7, "model-ac" : "1o7dC02" }, { "signature" : { "accession" : "SSF74650", "name" : "Galactose mutarotase-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR011013", "name" : "Gal_mutarotase_sf_dom", "description" : "Galactose mutarotase-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" }, { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" }, { "name" : "carbohydrate binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0030246" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 637, "end" : 1151, "hmmLength" : 522, "location-fragments" : [ { "start" : 637, "end" : 1151, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.35E-114, "model-ac" : "0047240" }, { "signature" : { "accession" : "G3DSA:2.70.98.30", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 736, "end" : 1018, "hmmStart" : 22, "hmmEnd" : 277, "hmmLength" : 280, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-75, "score" : 255.7, "envelopeStart" : 736, "envelopeEnd" : 1018, "postProcessed" : true, "location-fragments" : [ { "start" : 736, "end" : 1018, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.1E-76, "score" : 256.6, "model-ac" : "3bvxA04" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 47, "end" : 95, "location-fragments" : [ { "start" : 47, "end" : 95, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF01074", "name" : "Glyco_hydro_38N", "description" : "Glycosyl hydrolases family 38 N-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000602", "name" : "Glyco_hydro_38_N", "description" : "Glycoside hydrolase family 38, N-terminal domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "alpha-mannosidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004559" }, { "name" : "mannose metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006013" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 153, "end" : 479, "hmmStart" : 1, "hmmEnd" : 289, "hmmLength" : 289, "hmmBounds" : "COMPLETE", "evalue" : 9.7E-90, "score" : 300.8, "envelopeStart" : 153, "envelopeEnd" : 479, "postProcessed" : true, "location-fragments" : [ { "start" : 153, "end" : 479, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.9E-90, "score" : 301.3, "model-ac" : "PF01074" }, { "signature" : { "accession" : "PTHR11607", "name" : "ALPHA-MANNOSIDASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 115, "end" : 1151, "hmmStart" : 100, "hmmEnd" : 1076, "hmmLength" : 1076, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 13, "envelopeEnd" : 1151, "location-fragments" : [ { "start" : 115, "end" : 1151, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "ALPHA-MANNOSIDASE 2X", "score" : 1245.1, "model-ac" : "PTHR11607" }, { "signature" : { "accession" : "SM00872", "name" : "Alpha_mann_mid_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR015341", "name" : "Glyco_hydro_38_cen", "description" : "Glycoside hydrolase family 38, central domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "alpha-mannosidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004559" }, { "name" : "mannose metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006013" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 488, "end" : 576, "hmmStart" : 1, "hmmEnd" : 90, "hmmLength" : 90, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-25, "score" : 101.2, "location-fragments" : [ { "start" : 488, "end" : 576, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-25, "score" : 101.2, "model-ac" : "SM00872" }, { "signature" : { "accession" : "G3DSA:1.20.1270.50", "name" : "Families 57/38 glycoside transferase middle domain", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR037094", "name" : "Glyco_hydro_38_cen_sf", "description" : "Glycoside hydrolase family 38, central domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "alpha-mannosidase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004559" }, { "name" : "mannose metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006013" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 487, "end" : 607, "hmmStart" : 3, "hmmEnd" : 101, "hmmLength" : 111, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-33, "score" : 116.2, "envelopeStart" : 487, "envelopeEnd" : 607, "postProcessed" : true, "location-fragments" : [ { "start" : 487, "end" : 607, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-34, "score" : 117.6, "model-ac" : "1htyA02" }, { "signature" : { "accession" : "SSF88688", "name" : "Families 57/38 glycoside transferase middle domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR028995", "name" : "Glyco_hydro_57/38_cen_sf", "description" : "Glycoside hydrolase families 57/38, central domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 488, "end" : 597, "hmmLength" : 111, "location-fragments" : [ { "start" : 488, "end" : 597, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.16E-27, "model-ac" : "0047239" } ], "xref" : [ { "name" : "XP_018910536.1 PREDICTED: alpha-mannosidase 2 [Bemisia tabaci]", "id" : "XP_018910536.1" }, { "name" : "XP_018910535.1 PREDICTED: alpha-mannosidase 2 [Bemisia tabaci]", "id" : "XP_018910535.1" } ] },{ "sequence" : "MAQSSIKSFFPTRKRPVVVDLKKVFDAPTSNVEHAAKRIRLSQKSPPAEDDADLKKIKKIEATPEATGTSSCVRVEQQSILEQRKEEEIILVRASKPGNKSGKTPEPAISNERPTTPDKAPSLEENITRDTPEPTNSSNSTNQEVGRPSTPDNSPSLEEKINEGLGLNDLKVKINRSKYYNALKDSLSRYQSRDARLKDIARRLQTNSSFEIEVPVSPVKSPLKPQKLFSSPIKTPQKGLGRRLDYTSPVKPNVYVSPRKLLEERPSPVKAVPCHLKFESLVNGDALILPFKYRSLFEIFCSVDTVSSLFHNRNEKITFSKLKAGVQEMLRRNFSESHLAQIKTVLPGAFEFSQEKYQVFGKRSEAVYHLIIRPVIKNRNGDLQEAQSSMTPTVLAARKREFSNCLLEITKRHHREFLLSLDPPLDIPTEKVTRWHAEFEVNAVPDIPQAELPVSPVQNNQLSAKDVLANAKSLLKANAKVTAAIENLSKRLEGQTEIESPRKPFPSFSVPCHSPKPTATGSAMDAVEAASKALKGVPQSLLNKIKAKQAARAVEAMTRSPAQNKKAVMLSRLPEIARVVRNLFVVERKSVLPLDQVTVKLEHSCREKLSPDEIRSHLSLIQDHAPEWLSMCLVRNANYVKLHRTADVEAVMLKLNKLVETEGRIYHCR", "md5" : "c76c69a08163220df63b7bf33c21276a", "matches" : [ { "signature" : { "accession" : "cd08674", "name" : "Cdt1_m", "description" : "Cdt1_m", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 289, "end" : 456, "sites" : [ ], "evalue" : 4.01232E-59, "score" : 194.836, "location-fragments" : [ { "start" : 289, "end" : 456, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd08674" }, { "signature" : { "accession" : "PF16679", "name" : "CDT1_C", "description" : "DNA replication factor Cdt1 C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR032054", "name" : "Cdt1_C", "description" : "DNA replication factor Cdt1, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "CDT1 association with the CDC6:ORC:origin complex", "databaseName" : "Reactome", "id" : "R-HSA-68827" }, { "name" : "Orc1 removal from chromatin", "databaseName" : "Reactome", "id" : "R-HSA-68949" }, { "name" : "Assembly of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68867" }, { "name" : "Activation of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68962" }, { "name" : "G1/S-Specific Transcription", "databaseName" : "Reactome", "id" : "R-HSA-69205" } ] } }, "locations" : [ { "start" : 540, "end" : 632, "hmmStart" : 1, "hmmEnd" : 93, "hmmLength" : 96, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 6.1E-26, "score" : 90.7, "envelopeStart" : 540, "envelopeEnd" : 635, "postProcessed" : true, "location-fragments" : [ { "start" : 540, "end" : 632, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-26, "score" : 91.6, "model-ac" : "PF16679" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 36, "end" : 162, "location-fragments" : [ { "start" : 36, "end" : 162, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 128, "end" : 157, "location-fragments" : [ { "start" : 128, "end" : 157, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF08839", "name" : "CDT1", "description" : "DNA replication factor CDT1 like", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR014939", "name" : "CDT1_Gemini-bd-like", "description" : "CDT1 Geminin-binding domain-like", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Activation of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68962" }, { "name" : "G1/S-Specific Transcription", "databaseName" : "Reactome", "id" : "R-HSA-69205" }, { "name" : "Assembly of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68867" }, { "name" : "Orc1 removal from chromatin", "databaseName" : "Reactome", "id" : "R-HSA-68949" }, { "name" : "CDT1 association with the CDC6:ORC:origin complex", "databaseName" : "Reactome", "id" : "R-HSA-68827" } ] } }, "locations" : [ { "start" : 289, "end" : 453, "hmmStart" : 1, "hmmEnd" : 177, "hmmLength" : 177, "hmmBounds" : "COMPLETE", "evalue" : 1.0E-51, "score" : 175.7, "envelopeStart" : 289, "envelopeEnd" : 453, "postProcessed" : true, "location-fragments" : [ { "start" : 289, "end" : 453, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-51, "score" : 175.7, "model-ac" : "PF08839" }, { "signature" : { "accession" : "SM01075", "name" : "CDT1_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR014939", "name" : "CDT1_Gemini-bd-like", "description" : "CDT1 Geminin-binding domain-like", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Activation of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68962" }, { "name" : "G1/S-Specific Transcription", "databaseName" : "Reactome", "id" : "R-HSA-69205" }, { "name" : "Assembly of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68867" }, { "name" : "Orc1 removal from chromatin", "databaseName" : "Reactome", "id" : "R-HSA-68949" }, { "name" : "CDT1 association with the CDC6:ORC:origin complex", "databaseName" : "Reactome", "id" : "R-HSA-68827" } ] } }, "locations" : [ { "start" : 289, "end" : 454, "hmmStart" : 1, "hmmEnd" : 206, "hmmLength" : 206, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-61, "score" : 220.6, "location-fragments" : [ { "start" : 289, "end" : 454, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-61, "score" : 220.6, "model-ac" : "SM01075" }, { "signature" : { "accession" : "PTHR28637:SF1", "name" : "DNA REPLICATION FACTOR CDT1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 232, "end" : 662, "hmmStart" : 56, "hmmEnd" : 531, "hmmLength" : 534, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 181, "envelopeEnd" : 665, "location-fragments" : [ { "start" : 232, "end" : 662, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-79, "familyName" : "DNA REPLICATION FACTOR CDT1", "score" : 271.4, "model-ac" : "PTHR28637:SF1" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 471, "end" : 491, "location-fragments" : [ { "start" : 471, "end" : 491, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 64, "end" : 78, "location-fragments" : [ { "start" : 64, "end" : 78, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF46785", "name" : "\"Winged helix\" DNA-binding domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036390", "name" : "WH_DNA-bd_sf", "description" : "Winged helix DNA-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 286, "end" : 456, "hmmLength" : 187, "location-fragments" : [ { "start" : 286, "end" : 456, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.69E-42, "model-ac" : "0050651" }, { "signature" : { "accession" : "cd08767", "name" : "Cdt1_c", "description" : "Cdt1_c", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 531, "end" : 656, "sites" : [ { "description" : "putative Cdt1-MCM complex binding site", "numLocations" : 13, "siteLocations" : [ { "start" : 635, "end" : 635, "residue" : "R" }, { "start" : 589, "end" : 589, "residue" : "K" }, { "start" : 656, "end" : 656, "residue" : "N" }, { "start" : 619, "end" : 619, "residue" : "S" }, { "start" : 552, "end" : 552, "residue" : "R" }, { "start" : 630, "end" : 630, "residue" : "S" }, { "start" : 653, "end" : 653, "residue" : "L" }, { "start" : 588, "end" : 588, "residue" : "R" }, { "start" : 593, "end" : 593, "residue" : "P" }, { "start" : 623, "end" : 623, "residue" : "D" }, { "start" : 615, "end" : 615, "residue" : "R" }, { "start" : 632, "end" : 632, "residue" : "C" }, { "start" : 548, "end" : 548, "residue" : "K" } ] } ], "evalue" : 2.6042E-42, "score" : 147.044, "location-fragments" : [ { "start" : 531, "end" : 656, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd08767" }, { "signature" : { "accession" : "G3DSA:1.10.10.1420", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 528, "end" : 664, "hmmStart" : 4, "hmmEnd" : 136, "hmmLength" : 138, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-47, "score" : 162.4, "envelopeStart" : 528, "envelopeEnd" : 664, "postProcessed" : true, "location-fragments" : [ { "start" : 528, "end" : 664, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.0E-48, "score" : 164.3, "model-ac" : "2kloA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 37, "end" : 62, "location-fragments" : [ { "start" : 37, "end" : 62, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 79, "end" : 93, "location-fragments" : [ { "start" : 79, "end" : 93, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR28637", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 232, "end" : 662, "hmmStart" : 56, "hmmEnd" : 531, "hmmLength" : 534, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 181, "envelopeEnd" : 665, "location-fragments" : [ { "start" : 232, "end" : 662, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-79, "familyName" : "DNA REPLICATION FACTOR CDT1", "score" : 271.4, "model-ac" : "PTHR28637" } ], "xref" : [ { "name" : "XP_018909690.1 PREDICTED: DNA replication factor Cdt1 isoform X1 [Bemisia tabaci]", "id" : "XP_018909690.1" } ] },{ "sequence" : "MNRDKNNRSFMERSGDDDADDSDDASNTVRKKASACCVNTCSSDANINNHSENLELNVCSGETGTGNSSNNPHTAENKHYPTNKIIEVDTPPPKKERIEAPTEENALLRRSHDAAHKKAESMEFFSSLVANLNLRRRNFPSQESRIGINYFPSELSERIENEIEDDTSDGDGVSMLSRPVRFSRSRTSLLSQKFAAIAPRPCSRLEIIFEKSQRLQNEEIVDNLLSSLDILLPSCKPEISEENDNSLKVIIDSNKKINDHTKWNPSQIKEDKKVDVSQCDSAVKQAPMYPGGGGNKMQGTYRFPTGDSNSGAGSQPNYSSNMNNSGPGFRGPRPGFSSLLSNVSSVDLSPFRGGAPIRFRLGTTPRMNPKKVQDKVPSAASQASSSPQSDSPTKEDEDVDLYSDIEHDPHEDVDEDKNFGTLEPPPEPPALLMGLGDEGTDEEEALVIDDKGADVYDPAEPCDDSNDASDSRNDEPVEAMNLTKPSSGYLHSPTYNDIVAQHDDKIGNGSSYDGVPKMMEPPPIPDALKIMEPPPFPSELLSKEIQGDDDEECPNFSLYSSASMNLVKKSSSVLDIPIPAQSNLDIPIPTQPNLDIPMPGPPNLDIPVPGSPTVANIPVPNSGSKTEKSTKEKKKKKKKKPLMYSVPTLEETILKERLGNYSSEDNTDSDDSEEKVKIIIPKRKKKASKKSKKKLAEAEKVDEMNDDAFENVNGEKKPEEKEEEEKENEEEKIVEVNVELDDNDEQSNFDDVSESKAPEKEGGDETEGDTQDEVESKIVSESSMDSIRPQVDEQTIDDNQETVSSLDNSDVSKLPDDKSDSSKMAILSNEGKEKLYDGEDESSIQGDILDIEAEANLQDATSIPDEQDDIKSSTPSKSNAQKSDGLVDITDEEMSEYDHSREEPSNKLDSLNTEAISEDEASIVDGNKESEQSCPTLPGLEGLQTDPISDSDGNAFDESNYSADKESEYDGGKRRKKKKKVQKEKEQSASENEDANVSKSKEKRNSADFEEGEIVDDKPKSSSKKDKKKKAKDKEAKENLDRSKSDHEKDKEKDKKQKKSKDGKSKDKDSVLQSSENKSSEENKEGSPSQSAADVNWKKLSKSTKDRNYRDGKGKPTNDKGRKSPERSTPKEREKKKEKRKELERYNVRKVLGEKVRLIGKDDFGRDLSLNRSMSRSRSRSRNRKGKGKSRSTSRSPYRSPVRSRAARSRSRSRSRSRSRRRLGRKRSRSKNRTLRRSYDRSRSKSRGRSRDRLRKKRASSRDRLRRSLSKGRVSRKKKKSVERRRNRSYSPEYSPARKRRSNSRYSFSPSWSSYSYSPSPGYSRSYSLSPSPSWSPENRALVYNREKNRPPKNITVIVPNEDANAKKKGKKRLSKKNKENEKRRKKRDRSPAPSKEVFTSGDNILVSVNFSNNKNDGTMGSLLHTNEYSTARRRSVEAEPPAKKSKETKNKEKKSKNSTPKKSRSARAVAVNEAAKNAKPIAVIDLNMSPFREETPSPKEVIVVTDSDLEAEQIEKEAPTSNRKVSRKSGSGRERDRDRDRDRDRDRDRNRDRDLGPPTSVSQPESPINDFMNTSAGGPKTPPEPRVAFSISSKQPQMRTMINPLMDGDEEEEQMEEANNEAEMNEIFSKGPNTPPEPPPDTNTPASPPTTPYDPFDPTKSRSPSPELGEQTSTPVNLRDGNKAHDTLSPNVLESNDLDSRNKTSPQVPDENKKTPDNLRSLQKDTIPILESPKQSSPNVSGVNDSNDGVVMKILGQAKIDLTTYKSPEPIAGTPRSTQLTPKPITPSKQSILSVSRAPAPASANKIPVYTPSITLNGEKMDEAPMDISGDSPYSPEPFEAEDLFEPPPISPPRTANKLPMPPIIRSSLTKANKSKFDALFGSLTRKTNTKQLKPVPYTPKPIIPSIKGTKAQKQMKGSKKEVGVKMDEDQLKILDDLPSSAVEMQVKDKYLKKLNRQERVVEEVKLVLKPHYAKKHIAKEDYKEILRRAVPKICHNRSGEINPQKIQMLIEAYVRKFQAKTSKKKGGAETTTNNTSNLSKRSKATRS", "md5" : "195eea0cac2abf140955cee05c7c98dc", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1689, "end" : 1704, "location-fragments" : [ { "start" : 1689, "end" : 1704, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1205, "end" : 1234, "location-fragments" : [ { "start" : 1205, "end" : 1234, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1767, "end" : 1800, "location-fragments" : [ { "start" : 1767, "end" : 1800, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 983, "end" : 1083, "location-fragments" : [ { "start" : 983, "end" : 1083, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1431, "end" : 1455, "location-fragments" : [ { "start" : 1431, "end" : 1455, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 518, "end" : 532, "location-fragments" : [ { "start" : 518, "end" : 532, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 657, "end" : 680, "location-fragments" : [ { "start" : 657, "end" : 680, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 289, "end" : 333, "location-fragments" : [ { "start" : 289, "end" : 333, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1370, "end" : 1384, "location-fragments" : [ { "start" : 1370, "end" : 1384, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1248, "end" : 1285, "location-fragments" : [ { "start" : 1248, "end" : 1285, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR12618", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1320, "end" : 2028, "hmmStart" : 911, "hmmEnd" : 1449, "hmmLength" : 1450, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1309, "envelopeEnd" : 2029, "location-fragments" : [ { "start" : 1320, "end" : 2028, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-45, "familyName" : "FAMILY NOT NAMED", "score" : 157.1, "model-ac" : "PTHR12618" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1343, "end" : 1401, "location-fragments" : [ { "start" : 1343, "end" : 1401, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1843, "end" : 1860, "location-fragments" : [ { "start" : 1843, "end" : 1860, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1705, "end" : 1721, "location-fragments" : [ { "start" : 1705, "end" : 1721, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1665, "end" : 1681, "location-fragments" : [ { "start" : 1665, "end" : 1681, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 692, "end" : 723, "location-fragments" : [ { "start" : 692, "end" : 723, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2023, "end" : 2049, "location-fragments" : [ { "start" : 2023, "end" : 2049, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 357, "end" : 553, "location-fragments" : [ { "start" : 357, "end" : 553, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1817, "end" : 1868, "location-fragments" : [ { "start" : 1817, "end" : 1868, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 719, "end" : 746, "location-fragments" : [ { "start" : 719, "end" : 746, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 391, "end" : 421, "location-fragments" : [ { "start" : 391, "end" : 421, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1418, "end" : 1746, "location-fragments" : [ { "start" : 1418, "end" : 1746, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 375, "end" : 390, "location-fragments" : [ { "start" : 375, "end" : 390, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 749, "end" : 764, "location-fragments" : [ { "start" : 749, "end" : 764, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 29, "location-fragments" : [ { "start" : 1, "end" : 29, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1099, "end" : 1169, "location-fragments" : [ { "start" : 1099, "end" : 1169, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1084, "end" : 1098, "location-fragments" : [ { "start" : 1084, "end" : 1098, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1771, "end" : 1799, "location-fragments" : [ { "start" : 1771, "end" : 1799, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 959, "end" : 973, "location-fragments" : [ { "start" : 959, "end" : 973, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 589, "end" : 1302, "location-fragments" : [ { "start" : 589, "end" : 1302, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1286, "end" : 1300, "location-fragments" : [ { "start" : 1286, "end" : 1300, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 15, "location-fragments" : [ { "start" : 1, "end" : 15, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1177, "end" : 1192, "location-fragments" : [ { "start" : 1177, "end" : 1192, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1729, "end" : 1746, "location-fragments" : [ { "start" : 1729, "end" : 1746, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 886, "end" : 908, "location-fragments" : [ { "start" : 886, "end" : 908, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 796, "end" : 810, "location-fragments" : [ { "start" : 796, "end" : 810, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 2026, "end" : 2049, "location-fragments" : [ { "start" : 2026, "end" : 2049, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1037, "end" : 1057, "location-fragments" : [ { "start" : 1037, "end" : 1057, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 1606, "end" : 1626, "location-fragments" : [ { "start" : 1606, "end" : 1626, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1506, "end" : 1556, "location-fragments" : [ { "start" : 1506, "end" : 1556, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 592, "end" : 608, "location-fragments" : [ { "start" : 592, "end" : 608, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 301, "end" : 327, "location-fragments" : [ { "start" : 301, "end" : 327, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1557, "end" : 1577, "location-fragments" : [ { "start" : 1557, "end" : 1577, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 724, "end" : 748, "location-fragments" : [ { "start" : 724, "end" : 748, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1633, "end" : 1656, "location-fragments" : [ { "start" : 1633, "end" : 1656, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910053.1 PREDICTED: serine/arginine repetitive matrix protein 2-like isoform X3 [Bemisia tabaci]", "id" : "XP_018910053.1" } ] },{ "sequence" : "MVQQEVGVLGTCHNMMGYGQTTQGYNKLFTQGSADSNYSQPSSELSLDEEKEAIRREKERQAKSQLDRARLKPVAFAVRTNVCYDGKLDDDSPIHGSAISFDVKDYLHIKEKYDNNWWIGRLVKTGSDVGFIPSPVKLENLRLQQSQARNSKLYSSKTSSSSNLGALALANDIVSTSKSANAHSRGSTPPTPGEDSDSVGNAKLPGKSLTSAPTKEKRKPFFRKQEITAPYDVVPSMRPVVLVGPSLKGYQVTDMMQKALFDYLKHRFEGRIIITRVEADISLAKRSLLNNPSKRAVMERSNSRSTCLAEVQAEIERIFELARTLQLVVLDCDTINHPSQLAKTSLAPCIVYLKISSPKVLQRLIKSRGKSQTRHLNVQMVAAEKLAQCPPEMFDLILDENQLEDACTHIADYLETYWSATHPTVDQPPAPVPRPIQQPSPALDHPANLGRVTSTPPGLHPEDYDYPQDQRGGYHHPPRGRSRIVRERGEMSEYEDSGVSVVSRDGMIMYHPHGQHPHPHQQHPHHHPQHQSPPGGPYAHPDPRGREMYQRGLSGEERYPERHRAPLHDPEEYHPHHSHRASSKRALNAV", "md5" : "46181dde250c02eb9d89e6325aaaa0d4", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 178, "end" : 221, "location-fragments" : [ { "start" : 178, "end" : 221, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00072", "name" : "gk_7", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR008145", "name" : "GK/Ca_channel_bsu", "description" : "Guanylate kinase/L-type calcium channel beta subunit", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 236, "end" : 418, "hmmStart" : 1, "hmmEnd" : 203, "hmmLength" : 203, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-27, "score" : 106.0, "location-fragments" : [ { "start" : 236, "end" : 418, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-27, "score" : 106.0, "model-ac" : "SM00072" }, { "signature" : { "accession" : "PF00625", "name" : "Guanylate_kin", "description" : "Guanylate kinase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR008145", "name" : "GK/Ca_channel_bsu", "description" : "Guanylate kinase/L-type calcium channel beta subunit", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 236, "end" : 416, "hmmStart" : 1, "hmmEnd" : 181, "hmmLength" : 182, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.8E-47, "score" : 160.7, "envelopeStart" : 236, "envelopeEnd" : 417, "postProcessed" : true, "location-fragments" : [ { "start" : 236, "end" : 416, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.8E-47, "score" : 161.4, "model-ac" : "PF00625" }, { "signature" : { "accession" : "G3DSA:2.30.30.40", "name" : "SH3 Domains", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 39, "end" : 157, "hmmStart" : 2, "hmmEnd" : 113, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 5.6E-43, "score" : 147.6, "envelopeStart" : 39, "envelopeEnd" : 157, "postProcessed" : true, "location-fragments" : [ { "start" : 39, "end" : 157, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-43, "score" : 148.9, "model-ac" : "4deyA01" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 422, "end" : 590, "location-fragments" : [ { "start" : 422, "end" : 590, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR11824", "name" : "VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 27, "end" : 442, "hmmStart" : 3, "hmmEnd" : 408, "hmmLength" : 489, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 21, "envelopeEnd" : 582, "location-fragments" : [ { "start" : 27, "end" : 442, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.0E-224, "familyName" : "CA2+-CHANNEL-PROTEIN-BETA-SUBUNIT, ISOFORM L", "score" : 746.5, "model-ac" : "PTHR11824" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 45, "end" : 59, "location-fragments" : [ { "start" : 45, "end" : 59, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF50044", "name" : "SH3-domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036028", "name" : "SH3-like_dom_sf", "description" : "SH3-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 54, "end" : 234, "hmmLength" : 145, "location-fragments" : [ { "start" : 199, "end" : 234, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 54, "end" : 161, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 4.59E-34, "model-ac" : "0044917" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 39, "end" : 59, "location-fragments" : [ { "start" : 39, "end" : 59, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.40.50.300", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 213, "end" : 434, "hmmStart" : 2, "hmmEnd" : 218, "hmmLength" : 224, "hmmBounds" : "COMPLETE", "evalue" : 1.0E-109, "score" : 366.9, "envelopeStart" : 213, "envelopeEnd" : 434, "postProcessed" : true, "location-fragments" : [ { "start" : 213, "end" : 434, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-110, "score" : 367.6, "model-ac" : "1t0jB00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 178, "end" : 195, "location-fragments" : [ { "start" : 178, "end" : 195, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd11863", "name" : "SH3_CACNB", "description" : "SH3_CACNB", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 76, "end" : 137, "sites" : [ { "description" : "peptide ligand binding site", "numLocations" : 9, "siteLocations" : [ { "start" : 84, "end" : 84, "residue" : "Y" }, { "start" : 133, "end" : 133, "residue" : "P" }, { "start" : 87, "end" : 87, "residue" : "K" }, { "start" : 117, "end" : 117, "residue" : "W" }, { "start" : 82, "end" : 82, "residue" : "V" }, { "start" : 135, "end" : 135, "residue" : "P" }, { "start" : 136, "end" : 136, "residue" : "V" }, { "start" : 116, "end" : 116, "residue" : "N" }, { "start" : 98, "end" : 98, "residue" : "A" } ] } ], "evalue" : 2.97987E-38, "score" : 133.172, "location-fragments" : [ { "start" : 76, "end" : 137, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd11863" }, { "signature" : { "accession" : "SSF52540", "name" : "P-loop containing nucleoside triphosphate hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR027417", "name" : "P-loop_NTPase", "description" : "P-loop containing nucleoside triphosphate hydrolase", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 235, "end" : 421, "hmmLength" : 187, "location-fragments" : [ { "start" : 235, "end" : 421, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.23E-43, "model-ac" : "0050317" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 426, "end" : 440, "location-fragments" : [ { "start" : 426, "end" : 440, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 544, "end" : 578, "location-fragments" : [ { "start" : 544, "end" : 578, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR11824:SF5", "name" : "CA2+-CHANNEL-PROTEIN-BETA-SUBUNIT, ISOFORM L", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 27, "end" : 442, "hmmStart" : 3, "hmmEnd" : 408, "hmmLength" : 489, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 21, "envelopeEnd" : 582, "location-fragments" : [ { "start" : 27, "end" : 442, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.0E-224, "familyName" : "CA2+-CHANNEL-PROTEIN-BETA-SUBUNIT, ISOFORM L", "score" : 746.5, "model-ac" : "PTHR11824:SF5" }, { "signature" : { "accession" : "PR01626", "name" : "LCACHANNELB", "description" : "L-type calcium channel beta subunit signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000584", "name" : "VDCC_L_bsu", "description" : "Voltage-dependent calcium channel, L-type, beta subunit", "type" : "FAMILY", "goXRefs" : [ { "name" : "voltage-gated calcium channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005245" }, { "name" : "calcium ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0070588" }, { "name" : "voltage-gated calcium channel complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005891" } ], "pathwayXRefs" : [ { "name" : "Presynaptic depolarization and calcium channel opening", "databaseName" : "Reactome", "id" : "R-HSA-112308" }, { "name" : "Phase 2 - plateau phase", "databaseName" : "Reactome", "id" : "R-HSA-5576893" }, { "name" : "Phase 0 - rapid depolarisation", "databaseName" : "Reactome", "id" : "R-HSA-5576892" }, { "name" : "NCAM1 interactions", "databaseName" : "Reactome", "id" : "R-HSA-419037" } ] } }, "locations" : [ { "start" : 260, "end" : 275, "pvalue" : 2.02E-10, "score" : 84.01, "motifNumber" : 3, "location-fragments" : [ { "start" : 260, "end" : 275, "dc-status" : "CONTINUOUS" } ] }, { "start" : 245, "end" : 259, "pvalue" : 8.15E-10, "score" : 93.33, "motifNumber" : 2, "location-fragments" : [ { "start" : 245, "end" : 259, "dc-status" : "CONTINUOUS" } ] }, { "start" : 325, "end" : 340, "pvalue" : 4.45E-10, "score" : 85.48, "motifNumber" : 6, "location-fragments" : [ { "start" : 325, "end" : 340, "dc-status" : "CONTINUOUS" } ] }, { "start" : 343, "end" : 359, "pvalue" : 2.57E-11, "score" : 82.53, "motifNumber" : 7, "location-fragments" : [ { "start" : 343, "end" : 359, "dc-status" : "CONTINUOUS" } ] }, { "start" : 230, "end" : 244, "pvalue" : 1.77E-11, "score" : 95.49, "motifNumber" : 1, "location-fragments" : [ { "start" : 230, "end" : 244, "dc-status" : "CONTINUOUS" } ] }, { "start" : 380, "end" : 391, "pvalue" : 1.74E-7, "score" : 79.9, "motifNumber" : 9, "location-fragments" : [ { "start" : 380, "end" : 391, "dc-status" : "CONTINUOUS" } ] }, { "start" : 364, "end" : 379, "pvalue" : 4.47E-10, "score" : 83.82, "motifNumber" : 8, "location-fragments" : [ { "start" : 364, "end" : 379, "dc-status" : "CONTINUOUS" } ] }, { "start" : 310, "end" : 324, "pvalue" : 7.41E-9, "score" : 87.65, "motifNumber" : 5, "location-fragments" : [ { "start" : 310, "end" : 324, "dc-status" : "CONTINUOUS" } ] }, { "start" : 276, "end" : 290, "pvalue" : 3.26E-9, "score" : 83.92, "motifNumber" : 4, "location-fragments" : [ { "start" : 276, "end" : 290, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-77, "graphscan" : "IIIIIIIII", "model-ac" : "PR01626" }, { "signature" : { "accession" : "PF12052", "name" : "VGCC_beta4Aa_N", "description" : "Voltage gated calcium channel subunit beta domain 4Aa N terminal", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000584", "name" : "VDCC_L_bsu", "description" : "Voltage-dependent calcium channel, L-type, beta subunit", "type" : "FAMILY", "goXRefs" : [ { "name" : "voltage-gated calcium channel activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005245" }, { "name" : "calcium ion transmembrane transport", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0070588" }, { "name" : "voltage-gated calcium channel complex", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005891" } ], "pathwayXRefs" : [ { "name" : "Presynaptic depolarization and calcium channel opening", "databaseName" : "Reactome", "id" : "R-HSA-112308" }, { "name" : "Phase 2 - plateau phase", "databaseName" : "Reactome", "id" : "R-HSA-5576893" }, { "name" : "Phase 0 - rapid depolarisation", "databaseName" : "Reactome", "id" : "R-HSA-5576892" }, { "name" : "NCAM1 interactions", "databaseName" : "Reactome", "id" : "R-HSA-419037" } ] } }, "locations" : [ { "start" : 32, "end" : 72, "hmmStart" : 1, "hmmEnd" : 42, "hmmLength" : 42, "hmmBounds" : "COMPLETE", "evalue" : 1.4E-19, "score" : 69.8, "envelopeStart" : 32, "envelopeEnd" : 72, "postProcessed" : true, "location-fragments" : [ { "start" : 32, "end" : 72, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.7E-20, "score" : 71.1, "model-ac" : "PF12052" } ], "xref" : [ { "name" : "XP_018909671.1 PREDICTED: voltage-dependent L-type calcium channel subunit beta-1 isoform X1 [Bemisia tabaci]", "id" : "XP_018909671.1" } ] },{ "sequence" : "MSSPSAGKRRMDTDVIKLIESKHEVTILGGLNEFCVKFYGPRGTPYEGGIWKVRVHLPEHYPFKSPSIGFMNKVYHPNIDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPNPIDPLNGDAAAMYLHKPDEYKKKVHEYVRKYATEEALREQEHQAVSSDSESSMSDFSEDEAQDMEL", "md5" : "217001df0929fd6b0ecbb96cbe5e58b1", "matches" : [ { "signature" : { "accession" : "SSF54495", "name" : "UBC-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR016135", "name" : "UBQ-conjugating_enzyme/RWD", "description" : "Ubiquitin-conjugating enzyme/RWD-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 151, "hmmLength" : 152, "location-fragments" : [ { "start" : 7, "end" : 151, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.07E-45, "model-ac" : "0051310" }, { "signature" : { "accession" : "PF00179", "name" : "UQ_con", "description" : "Ubiquitin-conjugating enzyme", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000608", "name" : "UBQ-conjugat_E2", "description" : "Ubiquitin-conjugating enzyme E2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" } ] } }, "locations" : [ { "start" : 30, "end" : 144, "hmmStart" : 26, "hmmEnd" : 139, "hmmLength" : 140, "hmmBounds" : "INCOMPLETE", "evalue" : 9.0E-37, "score" : 125.8, "envelopeStart" : 9, "envelopeEnd" : 145, "postProcessed" : true, "location-fragments" : [ { "start" : 30, "end" : 144, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-37, "score" : 126.3, "model-ac" : "PF00179" }, { "signature" : { "accession" : "SM00212", "name" : "ubc_7", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : null }, "locations" : [ { "start" : 5, "end" : 150, "hmmStart" : 1, "hmmEnd" : 144, "hmmLength" : 144, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-52, "score" : 189.0, "location-fragments" : [ { "start" : 5, "end" : 150, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-52, "score" : 189.0, "model-ac" : "SM00212" }, { "signature" : { "accession" : "PS50127", "name" : "UBIQUITIN_CONJUGAT_2", "description" : "Ubiquitin-conjugating enzymes family profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000608", "name" : "UBQ-conjugat_E2", "description" : "Ubiquitin-conjugating enzyme E2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" } ] } }, "locations" : [ { "start" : 31, "end" : 139, "score" : 32.451, "alignment" : "---------------------------LNEFCVKFYGPRGTPYEGGIWKVRVHLPEHYPFKSPSIGFMNKVYHPNIDEVsGTVCLDVINQAWTALYDLSNIFESfLPQLLTYPNPIDPLNGDAAAMYLHKPDEYKK", "location-fragments" : [ { "start" : 31, "end" : 139, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50127" }, { "signature" : { "accession" : "G3DSA:3.10.110.10", "name" : "Ubiquitin Conjugating Enzyme", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR016135", "name" : "UBQ-conjugating_enzyme/RWD", "description" : "Ubiquitin-conjugating enzyme/RWD-like", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 6, "end" : 155, "hmmStart" : 6, "hmmEnd" : 149, "hmmLength" : 152, "hmmBounds" : "COMPLETE", "evalue" : 6.1E-51, "score" : 173.9, "envelopeStart" : 6, "envelopeEnd" : 155, "postProcessed" : true, "location-fragments" : [ { "start" : 6, "end" : 155, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.9E-51, "score" : 174.2, "model-ac" : "2onuA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 155, "end" : 183, "location-fragments" : [ { "start" : 155, "end" : 183, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00195", "name" : "UBCc", "description" : "UBCc", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR000608", "name" : "UBQ-conjugat_E2", "description" : "Ubiquitin-conjugating enzyme E2", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" } ] } }, "locations" : [ { "start" : 31, "end" : 145, "sites" : [ { "description" : "active site cysteine", "numLocations" : 1, "siteLocations" : [ { "start" : 87, "end" : 87, "residue" : "C" } ] }, { "description" : "Ub thioester intermediate interaction residues", "numLocations" : 21, "siteLocations" : [ { "start" : 117, "end" : 117, "residue" : "N" }, { "start" : 81, "end" : 81, "residue" : "E" }, { "start" : 86, "end" : 86, "residue" : "V" }, { "start" : 119, "end" : 119, "residue" : "I" }, { "start" : 95, "end" : 95, "residue" : "W" }, { "start" : 74, "end" : 74, "residue" : "V" }, { "start" : 90, "end" : 90, "residue" : "V" }, { "start" : 91, "end" : 91, "residue" : "I" }, { "start" : 78, "end" : 78, "residue" : "N" }, { "start" : 99, "end" : 99, "residue" : "Y" }, { "start" : 115, "end" : 115, "residue" : "Y" }, { "start" : 120, "end" : 120, "residue" : "D" }, { "start" : 96, "end" : 96, "residue" : "T" }, { "start" : 107, "end" : 107, "residue" : "S" }, { "start" : 79, "end" : 79, "residue" : "I" }, { "start" : 88, "end" : 88, "residue" : "L" }, { "start" : 110, "end" : 110, "residue" : "P" }, { "start" : 87, "end" : 87, "residue" : "C" }, { "start" : 104, "end" : 104, "residue" : "I" }, { "start" : 114, "end" : 114, "residue" : "T" }, { "start" : 73, "end" : 73, "residue" : "K" } ] } ], "evalue" : 1.35147E-49, "score" : 155.053, "location-fragments" : [ { "start" : 31, "end" : 145, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00195" }, { "signature" : { "accession" : "PTHR24068", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 177, "hmmStart" : 4, "hmmEnd" : 171, "hmmLength" : 184, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 182, "location-fragments" : [ { "start" : 8, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-69, "familyName" : "UBIQUITIN-CONJUGATING ENZYME E2 H", "score" : 235.2, "model-ac" : "PTHR24068" }, { "signature" : { "accession" : "PS00183", "name" : "UBIQUITIN_CONJUGAT_1", "description" : "Ubiquitin-conjugating enzymes active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR023313", "name" : "UBQ-conjugating_AS", "description" : "Ubiquitin-conjugating enzyme, active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" }, { "name" : "Protein ubiquitination", "databaseName" : "MetaCyc", "id" : "PWY-7511" } ] } }, "locations" : [ { "start" : 75, "end" : 91, "level" : "STRONG", "cigarAlignment" : "5M4I1M1I3M2I1M", "alignment" : "YHPNIdevsGtVCLdvI", "location-fragments" : [ { "start" : 75, "end" : 91, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00183" }, { "signature" : { "accession" : "PTHR24068:SF128", "name" : "UBIQUITIN-CONJUGATING ENZYME E2 H", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 177, "hmmStart" : 4, "hmmEnd" : 171, "hmmLength" : 184, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 182, "location-fragments" : [ { "start" : 8, "end" : 177, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.1E-69, "familyName" : "UBIQUITIN-CONJUGATING ENZYME E2 H", "score" : 235.2, "model-ac" : "PTHR24068:SF128" } ], "xref" : [ { "name" : "XP_018909574.1 PREDICTED: ubiquitin-conjugating enzyme E2 H [Bemisia tabaci]", "id" : "XP_018909574.1" } ] },{ "sequence" : "MSTPIVSMLNSEQLLTCPYDQSHRFRRFKMLNHIRTCRLRYENEHPELAMKACLYNSAHIVPDVEWEYHMEECEDRIKGDLMRYQVERNPAFENNTVIPLSDIPDVECDEDWNLPQNPVSINAIIQEKIKEEKVLIPLIGAPKAERKKYYMEERRRHNTLEDAKPSTSNTSVPVDKNQPLRKPKTISELSAGPSCAPPFSQQVPPNLKSKETDEQRIDVNALEETSALVKGTVKPSRMFPKGRGRAPCNNVAASSQPEPKVGSSVPSSCRAAEPIPSVCDVSQNMTNLSIDPISFGSIGGDGSISNPIPNKGRGRKFLNRSA", "md5" : "27119e8d4c42da1969b8f0560253824b", "matches" : [ { "signature" : { "accession" : "PF05253", "name" : "zf-U11-48K", "description" : "U11-48K-like CHHC zinc finger", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR022776", "name" : "TRM13/UPF0224_CHHC_Znf_dom", "description" : "TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 38, "hmmStart" : 1, "hmmEnd" : 25, "hmmLength" : 25, "hmmBounds" : "COMPLETE", "evalue" : 6.4E-6, "score" : 26.0, "envelopeStart" : 14, "envelopeEnd" : 38, "postProcessed" : true, "location-fragments" : [ { "start" : 14, "end" : 38, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-8, "score" : 34.4, "model-ac" : "PF05253" }, { "signature" : { "accession" : "PS51800", "name" : "ZF_CHHC_U11_48K", "description" : "Zinc finger CHHC U11-48K-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR022776", "name" : "TRM13/UPF0224_CHHC_Znf_dom", "description" : "TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 50, "end" : 77, "score" : 11.986, "alignment" : "MKACLYNSAHIVPDVEWEYHMEECEDRI", "location-fragments" : [ { "start" : 50, "end" : 77, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51800" }, { "signature" : { "accession" : "PTHR21402:SF5", "name" : "GAMETOCYTE SPECIFIC FACTOR 1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 162, "hmmStart" : 10, "hmmEnd" : 144, "hmmLength" : 166, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 190, "location-fragments" : [ { "start" : 8, "end" : 162, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-15, "familyName" : "GAMETOCYTE SPECIFIC FACTOR 1", "score" : 60.4, "model-ac" : "PTHR21402:SF5" }, { "signature" : { "accession" : "PS51800", "name" : "ZF_CHHC_U11_48K", "description" : "Zinc finger CHHC U11-48K-type profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR022776", "name" : "TRM13/UPF0224_CHHC_Znf_dom", "description" : "TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 14, "end" : 41, "score" : 13.893, "alignment" : "LLTCPYDQSHRFRRFKMLNHIRTCRLRY", "location-fragments" : [ { "start" : 14, "end" : 41, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51800" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 299, "end" : 322, "location-fragments" : [ { "start" : 299, "end" : 322, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 155, "end" : 176, "location-fragments" : [ { "start" : 155, "end" : 176, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF57667", "name" : "beta-beta-alpha zinc fingers", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036236", "name" : "Znf_C2H2_sf", "description" : "Zinc finger C2H2 superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 13, "end" : 43, "hmmLength" : 35, "location-fragments" : [ { "start" : 13, "end" : 43, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.36E-5, "model-ac" : "0054735" }, { "signature" : { "accession" : "PTHR21402", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 162, "hmmStart" : 10, "hmmEnd" : 144, "hmmLength" : 166, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 190, "location-fragments" : [ { "start" : 8, "end" : 162, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-15, "familyName" : "GAMETOCYTE SPECIFIC FACTOR 1", "score" : 60.4, "model-ac" : "PTHR21402" } ], "xref" : [ { "name" : "XP_018909734.1 PREDICTED: protein D7-like [Bemisia tabaci]", "id" : "XP_018909734.1" } ] },{ "sequence" : "NVFVIAAILLERNLQNVANYLILSLAVADLLVACLVMPLGAVYEVSRQWTLGPELCDMWTSSDVLCCTASILHLVAIALDRYWAVTNIDYIHQRTGKRIGIMILVIWTVSFLVCIAPLLGWKDPEWETRVLQQRTCLVSQDIGYQIFATASSFYLPLFVILVLYWRIFQAARKRIRRRVQASAVAKISSHGTVKYPPSGGVVAGLCAAGATGGNGGIAAAVIGVIGQPLPTISELTTTTTTAMTNVSSANSSPEKGSFGNGLEEDAPPTVNGPSLPTLVPPSPLPPPLKPPPPPPPKRKKESADSKRERKAAKTLAIITGAFVICWLPFFIMAILLPICSRYQCQLNQYLIAFFLWLGYFNSTLNPIIYTIFSPEFRHAFKRILCGRKNSVRRRNRHLGVRHMH", "md5" : "554c3ff7e3f5354d943dc9633b4bbd2c", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 243, "end" : 306, "location-fragments" : [ { "start" : 243, "end" : 306, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR24247:SF201", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 403, "hmmStart" : 2, "hmmEnd" : 402, "hmmLength" : 403, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 404, "location-fragments" : [ { "start" : 1, "end" : 403, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.5E-188, "familyName" : "", "score" : 627.4, "model-ac" : "PTHR24247:SF201" }, { "signature" : { "accession" : "PR00237", "name" : "GPCRRHODOPSN", "description" : "Rhodopsin-like GPCR superfamily signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : { "accession" : "IPR000276", "name" : "GPCR_Rhodpsn", "description" : "G protein-coupled receptor, rhodopsin-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "G protein-coupled receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004930" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "G protein-coupled receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007186" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 98, "end" : 119, "pvalue" : 0.00195, "score" : 22.63, "motifNumber" : 4, "location-fragments" : [ { "start" : 98, "end" : 119, "dc-status" : "CONTINUOUS" } ] }, { "start" : 351, "end" : 377, "pvalue" : 2.17E-11, "score" : 37.08, "motifNumber" : 7, "location-fragments" : [ { "start" : 351, "end" : 377, "dc-status" : "CONTINUOUS" } ] }, { "start" : 63, "end" : 85, "pvalue" : 1.64E-10, "score" : 39.88, "motifNumber" : 3, "location-fragments" : [ { "start" : 63, "end" : 85, "dc-status" : "CONTINUOUS" } ] }, { "start" : 18, "end" : 39, "pvalue" : 1.66E-10, "score" : 40.38, "motifNumber" : 2, "location-fragments" : [ { "start" : 18, "end" : 39, "dc-status" : "CONTINUOUS" } ] }, { "start" : 311, "end" : 335, "pvalue" : 6.64E-10, "score" : 35.94, "motifNumber" : 6, "location-fragments" : [ { "start" : 311, "end" : 335, "dc-status" : "CONTINUOUS" } ] }, { "start" : 145, "end" : 168, "pvalue" : 9.81E-8, "score" : 28.69, "motifNumber" : 5, "location-fragments" : [ { "start" : 145, "end" : 168, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-44, "graphscan" : ".IIiiII", "model-ac" : "PR00237" }, { "signature" : { "accession" : "SSF81321", "name" : "Family A G protein-coupled receptor-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 400, "hmmLength" : 348, "location-fragments" : [ { "start" : 1, "end" : 176, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 297, "end" : 400, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 7.87E-75, "model-ac" : "0037432" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 243, "end" : 257, "location-fragments" : [ { "start" : 243, "end" : 257, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 273, "end" : 293, "location-fragments" : [ { "start" : 273, "end" : 293, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd15331", "name" : "7tmA_5-HT1A_invertebrates", "description" : "7tmA_5-HT1A_invertebrates", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 380, "sites" : [ { "description" : "putative ligand binding site", "numLocations" : 18, "siteLocations" : [ { "start" : 329, "end" : 329, "residue" : "F" }, { "start" : 352, "end" : 352, "residue" : "A" }, { "start" : 60, "end" : 60, "residue" : "T" }, { "start" : 336, "end" : 336, "residue" : "L" }, { "start" : 348, "end" : 348, "residue" : "Q" }, { "start" : 355, "end" : 355, "residue" : "L" }, { "start" : 148, "end" : 148, "residue" : "A" }, { "start" : 64, "end" : 64, "residue" : "V" }, { "start" : 152, "end" : 152, "residue" : "S" }, { "start" : 351, "end" : 351, "residue" : "I" }, { "start" : 359, "end" : 359, "residue" : "Y" }, { "start" : 67, "end" : 67, "residue" : "C" }, { "start" : 68, "end" : 68, "residue" : "T" }, { "start" : 63, "end" : 63, "residue" : "D" }, { "start" : 330, "end" : 330, "residue" : "F" }, { "start" : 59, "end" : 59, "residue" : "W" }, { "start" : 136, "end" : 136, "residue" : "C" }, { "start" : 326, "end" : 326, "residue" : "W" } ] } ], "evalue" : 3.70239E-128, "score" : 367.835, "location-fragments" : [ { "start" : 1, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd15331" }, { "signature" : { "accession" : "G3DSA:1.20.1070.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 192, "hmmStart" : 38, "hmmEnd" : 215, "hmmLength" : 295, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-55, "score" : 189.3, "envelopeStart" : 1, "envelopeEnd" : 192, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 192, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.1E-85, "score" : 286.1, "model-ac" : "4iarA01" }, { "signature" : { "accession" : "PS00237", "name" : "G_PROTEIN_RECEP_F1_1", "description" : "G-protein coupled receptors family 1 signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR000276", "name" : "GPCR_Rhodpsn", "description" : "G protein-coupled receptor, rhodopsin-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "G protein-coupled receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004930" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "G protein-coupled receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007186" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 69, "end" : 85, "level" : "STRONG", "cigarAlignment" : "3M1I11M1I1M", "alignment" : "ASIlHLVAIALDRYWaV", "location-fragments" : [ { "start" : 69, "end" : 85, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00237" }, { "signature" : { "accession" : "G3DSA:1.20.1070.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 289, "end" : 390, "hmmStart" : 186, "hmmEnd" : 272, "hmmLength" : 274, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-33, "score" : 118.1, "envelopeStart" : 289, "envelopeEnd" : 390, "postProcessed" : true, "location-fragments" : [ { "start" : 289, "end" : 390, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-76, "score" : 257.1, "model-ac" : "3kj6A00" }, { "signature" : { "accession" : "PTHR24247", "name" : "5-HYDROXYTRYPTAMINE RECEPTOR", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 403, "hmmStart" : 2, "hmmEnd" : 402, "hmmLength" : 403, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 404, "location-fragments" : [ { "start" : 1, "end" : 403, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.5E-188, "familyName" : "", "score" : 627.4, "model-ac" : "PTHR24247" }, { "signature" : { "accession" : "SM01381", "name" : "7TM_GPCR_Srsx_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000276", "name" : "GPCR_Rhodpsn", "description" : "G protein-coupled receptor, rhodopsin-like", "type" : "FAMILY", "goXRefs" : [ { "name" : "G protein-coupled receptor activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004930" }, { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" }, { "name" : "G protein-coupled receptor signaling pathway", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0007186" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 384, "hmmStart" : 1, "hmmEnd" : 284, "hmmLength" : 284, "hmmBounds" : "COMPLETE", "evalue" : 3.6E-5, "score" : -33.3, "location-fragments" : [ { "start" : 1, "end" : 384, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-5, "score" : -33.3, "model-ac" : "SM01381" }, { "signature" : { "accession" : "PS50262", "name" : "G_PROTEIN_RECEP_F1_2", "description" : "G-protein coupled receptors family 1 profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR017452", "name" : "GPCR_Rhodpsn_7TM", "description" : "GPCR, rhodopsin-like, 7TM", "type" : "DOMAIN", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 369, "score" : 42.278, "alignment" : "-NVFVIAAILLERNLQNVANYLILSLAVADLLVACLVMPLGAVYEVSRQWTLGPELCDMWTSSDVLCCTASILHLVAIALDRYWAVTniDYIHQ---RTGKRIGIMILVIWTVSFLVCIAPLLGwkDPEWETRVLQQRTCLV------SQDIGYQIFAT-ASSFYLPLFVILVLYWRIFQAARKRIRRRVQAsavakisshgtvkyppsggvvaglcaagatggnggiaaavigvigqplptiselttttttamtnvssansspekgsfgngleedapptvngpslptlvppsplppplkpppppppkrkKESADSKRERKAAKTLAIITGAFVICWLPFFIMAILLPIC-SRYQCQLNQYLIAFFLWLGYFNSTLNPIIY", "location-fragments" : [ { "start" : 1, "end" : 369, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50262" }, { "signature" : { "accession" : "PF00001", "name" : "7tm_1", "description" : "7 transmembrane receptor (rhodopsin family)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR017452", "name" : "GPCR_Rhodpsn_7TM", "description" : "GPCR, rhodopsin-like, 7TM", "type" : "DOMAIN", "goXRefs" : [ { "name" : "integral component of membrane", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0016021" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 369, "hmmStart" : 2, "hmmEnd" : 263, "hmmLength" : 263, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 1.0E-78, "score" : 264.3, "envelopeStart" : 1, "envelopeEnd" : 369, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 369, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.7E-79, "score" : 264.6, "model-ac" : "PF00001" } ], "xref" : [ { "name" : "XP_018909954.1 PREDICTED: 5-hydroxytryptamine receptor-like, partial [Bemisia tabaci]", "id" : "XP_018909954.1" } ] },{ "sequence" : "MAREKIESNHLWLSMACILVVLAQRNSTHPTSESEHTEGGLPLSSPPTPSFEGNSRDSRRFSVSIFREIAQEISARLAGNSQILSLNVTNIIIILILKGILYGAALIGTGALFGGFKHLQPHRSDVSGNQIREGLDPDEPVISESEVLMLLGYLMGETANKYDCLNRIACQDPKKATEYIHAAKMLLKGSNIFYKNNVPQYAKYQRVLDELQRAVDFGNSGGQCEELYSCSSSSNNYSNY", "md5" : "79820af285051a76fea39ff011033724", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 29, "end" : 54, "location-fragments" : [ { "start" : 29, "end" : 54, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910323.1 PREDICTED: uncharacterized protein LOC109039342 [Bemisia tabaci]", "id" : "XP_018910323.1" } ] },{ "sequence" : "MTSTFIRTKHQSAGKGETAFLVVLHLAVKLVVVLGATAPTTTEKADVFSFNSSHNADVFSSNSSHNADVFSSNTNHNNATHEKITFYRDPSVGSSRSSVDYYDDDDVHETSVWDIPIDTEHIQEITDADYYHERERYDEFEREVALEFRPLCSTIRRRISLKDDLYEYRPSHFTEVLCRKFQPLLTYGPHGYHYKSYSYHKYEQQCAYDGFKCIQRSQVMYLSRRRRDGDCWETTRQVIPSGCDCMWPISTLGEIKEVY", "md5" : "aa6781f7a5d663b61efce5d1361fe8d3", "matches" : [ ], "xref" : [ { "name" : "XP_018909598.1 PREDICTED: uncharacterized protein LOC109038838 [Bemisia tabaci]", "id" : "XP_018909598.1" } ] },{ "sequence" : "MGPTSPQSTAGGGQQNPQPNAGSSPSAGNGGGIGGLCGSGSSSMSGGSQGGASGGSMLNGQLPYSYMNQPIIMLFTTSSTLSPSQVVLADTILSYNGMGQNTVCPVNQMGVMYPSPNQYNNIIWC", "md5" : "1a2e97c1a5130d91023af4316b69ac78", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 36, "end" : 54, "location-fragments" : [ { "start" : 36, "end" : 54, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 54, "location-fragments" : [ { "start" : 1, "end" : 54, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 27, "location-fragments" : [ { "start" : 1, "end" : 27, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018910533.1 PREDICTED: uncharacterized protein LOC109039497 [Bemisia tabaci]", "id" : "XP_018910533.1" } ] },{ "sequence" : "MCTGSNTVPVDCGKSRNRNGDRASSDKVLWAEENNYINYGEEDQMNNYEGHIISHFVKDVKLISIHDLSSDSTKDKDRISGLDIQALVQLQSNLRSKKLKAFLFDGSRKAREFPKINSLRNLDRYVFLKLHVIWHSESIMVSTKIRISVFHQAGRNYETG", "md5" : "4112fbd54f4160747d9cca8eb5902d50", "matches" : [ ], "xref" : [ { "name" : "XP_018909884.1 PREDICTED: uncharacterized protein LOC109039017 isoform X4 [Bemisia tabaci]", "id" : "XP_018909884.1" } ] },{ "sequence" : "MRGSSSELLLDPQQELRKRKLLELAASSKGAKKQKRTCRQRAWFYSTSFLVMTSVSAGSSLLFLVPLYVDPAISTLVADFAPEPVTCTTVRREELLGIFNCSWSSCREGCTSDMYKCSHIYVAYTDHNDTRTEDAVLLVNIKGCGYPPEVKCANFTEDYGQEGAQFPCYYSRQNRTVVMAEYDRERQVRIIRHFFGLPFLVCFITSVALCIMHCRCSATDPPRTVRRVRVHNDAR", "md5" : "1681e475574a3bf29516e0fb2aa8cc71", "matches" : [ { "signature" : { "accession" : "PF16972", "name" : "TipE", "description" : "Na+ channel auxiliary subunit TipE", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR031578", "name" : "TipE", "description" : "Na+ channel auxiliary subunit TipE", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 135, "end" : 207, "hmmStart" : 236, "hmmEnd" : 307, "hmmLength" : 486, "hmmBounds" : "INCOMPLETE", "evalue" : 1.7E-11, "score" : 44.0, "envelopeStart" : 131, "envelopeEnd" : 213, "postProcessed" : true, "location-fragments" : [ { "start" : 135, "end" : 207, "dc-status" : "CONTINUOUS" } ] }, { "start" : 34, "end" : 126, "hmmStart" : 6, "hmmEnd" : 98, "hmmLength" : 486, "hmmBounds" : "INCOMPLETE", "evalue" : 1.3E-26, "score" : 93.9, "envelopeStart" : 30, "envelopeEnd" : 135, "postProcessed" : true, "location-fragments" : [ { "start" : 34, "end" : 126, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.1E-40, "score" : 137.6, "model-ac" : "PF16972" }, { "signature" : { "accession" : "PTHR12335", "name" : "TIPE PROTEIN TEMPERATURE-INDUCED PARALYTIC E", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR031578", "name" : "TipE", "description" : "Na+ channel auxiliary subunit TipE", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 232, "hmmStart" : 1, "hmmEnd" : 256, "hmmLength" : 280, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 234, "location-fragments" : [ { "start" : 1, "end" : 232, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-105, "familyName" : "TIPE HOMOLOG 1, ISOFORM B", "score" : 354.2, "model-ac" : "PTHR12335" }, { "signature" : { "accession" : "PTHR12335:SF4", "name" : "TIPE HOMOLOG 1, ISOFORM B", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 232, "hmmStart" : 1, "hmmEnd" : 256, "hmmLength" : 280, "hmmBounds" : "N_TERMINAL_COMPLETE", "envelopeStart" : 1, "envelopeEnd" : 234, "location-fragments" : [ { "start" : 1, "end" : 232, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-105, "familyName" : "TIPE HOMOLOG 1, ISOFORM B", "score" : 354.2, "model-ac" : "PTHR12335:SF4" } ], "xref" : [ { "name" : "XP_018910351.1 PREDICTED: protein tipE isoform X2 [Bemisia tabaci]", "id" : "XP_018910351.1" } ] },{ "sequence" : "MLKSQSYLQWLFAQSLLILDMKDQIASATFDTFKSRRDSITMGISPWATFFLIFGCCVLSCCALEVSTPNGKIIGFDTLRTRDGRVIHSFTGIPFAKPPIGPLRFKEPQPADPWKEPLQATNDAIMCPQADFANISNYQPLGQEDCLVLHVYSPKVDRAAKLPVMVWIHGGGFQWGAGSVYGPELLLDKDVVLVTINYRLGALGFLSTGDNAIPANLGLKDQALAIKWVHDNIVNFGGNPDLVTIFGESAGGGAVHLNLLSPLNKGRIHRVIAMSGTGYGPWAIAPPKLAKDRTKALAVLCSCPTEPSNELAECMRKVPADVLLEMGKKFNDWIVGDLVFVPTIESETENAFLPKELDKLGSEIPYMTGLTSGEGGIFASIISRGGSRFEKELKENPQYVLSKALLLKSDFPSDKHSSVAEQVRKFYFGDKPIDLDNTSQEVVNMFTDRWFLHGAVESAKKHHGDAYLYLYDHLHSISFNDVFSGGRIKGVSHADDLLDIFPLTMYFPERKYTEDDIKVSRKTLDIVTDFAKIGKLTGIGSKLQPVRRTAKTNQYLHITAEPAVKENLYSKRLEFWQSLIDAQSEDTTVNAAWNTMPNMLLWLIPISVCLLCYCL", "md5" : "c81c2bc91582f7a0c81f9177e76a8c69", "matches" : [ { "signature" : { "accession" : "PF00135", "name" : "COesterase", "description" : "Carboxylesterase family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002018", "name" : "CarbesteraseB", "description" : "Carboxylesterase, type B", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 65, "end" : 576, "hmmStart" : 4, "hmmEnd" : 515, "hmmLength" : 515, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.9E-130, "score" : 435.6, "envelopeStart" : 63, "envelopeEnd" : 576, "postProcessed" : true, "location-fragments" : [ { "start" : 65, "end" : 576, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.4E-130, "score" : 435.9, "model-ac" : "PF00135" }, { "signature" : { "accession" : "PS00122", "name" : "CARBOXYLESTERASE_B_1", "description" : "Carboxylesterases type-B serine active site.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR019826", "name" : "Carboxylesterase_B_AS", "description" : "Carboxylesterase type B, active site", "type" : "ACTIVE_SITE", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 236, "end" : 251, "level" : "STRONG", "cigarAlignment" : "3M4I1M1I1M1I1M1I3M", "alignment" : "FGGnpdlVtIfGeSAG", "location-fragments" : [ { "start" : 236, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00122" }, { "signature" : { "accession" : "PTHR43142:SF1", "name" : "CARBOXYLIC ESTER HYDROLASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 65, "end" : 586, "hmmStart" : 28, "hmmEnd" : 564, "hmmLength" : 568, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 58, "envelopeEnd" : 590, "location-fragments" : [ { "start" : 65, "end" : 586, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-130, "familyName" : "CARBOXYLIC ESTER HYDROLASE", "score" : 437.1, "model-ac" : "PTHR43142:SF1" }, { "signature" : { "accession" : "G3DSA:3.40.50.1820", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 58, "end" : 586, "hmmStart" : 40, "hmmEnd" : 571, "hmmLength" : 577, "hmmBounds" : "COMPLETE", "evalue" : 1.8E-145, "score" : 487.9, "envelopeStart" : 58, "envelopeEnd" : 586, "postProcessed" : true, "location-fragments" : [ { "start" : 58, "end" : 586, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-145, "score" : 488.3, "model-ac" : "5ch5A00" }, { "signature" : { "accession" : "PTHR43142", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 65, "end" : 586, "hmmStart" : 28, "hmmEnd" : 564, "hmmLength" : 568, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 58, "envelopeEnd" : 590, "location-fragments" : [ { "start" : 65, "end" : 586, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.8E-130, "familyName" : "CARBOXYLIC ESTER HYDROLASE", "score" : 437.1, "model-ac" : "PTHR43142" }, { "signature" : { "accession" : "SSF53474", "name" : "alpha/beta-Hydrolases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR029058", "name" : "AB_hydrolase", "description" : "Alpha/Beta hydrolase fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 64, "end" : 580, "hmmLength" : 579, "location-fragments" : [ { "start" : 64, "end" : 580, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.0E-115, "model-ac" : "0045186" } ], "xref" : [ { "name" : "XP_018910006.1 PREDICTED: esterase E4-like isoform X2 [Bemisia tabaci]", "id" : "XP_018910006.1" } ] },{ "sequence" : "MDKEQIILFAGITGCALALAAYVIWGPSPTRKKKGPIVGLRNLGMTCFLNTVLQSLASCSFFVEWSVSLPRKGNLTQTIEKILRILNGEVNGVDIPYSPIEIVSAIRKHGWTMPHSEHDAHEFFHVVLTSIEEEITKNSPLRKSCLLDVLEEEPSSTEEKHQDHGDTPPDTQNISIVENKIIVSNGDIAPTRSFACINKTSLSLVDKSKPSPFKGFLTSQLKCTGCGFVSPLRYDPFDSISLHLPSASSVLTHYSLTQLLDKFVETEQVEGVECEGCNKNRAETTPVISTEALKTLRFGKLPKCLCFHISRLTMQSNGTTYKRQDTVEFSEYLTMDPYTHNTLIKKNISNNKISKETNESNGSIRPEDIPECKNHLYRLKAVIVHCGSSEWGGHFITYRHGYLRSQTRHRCKDSRNNPRWFYTSDEEVRQTSLAEVLSSLPYMLFYEKCETPGPED", "md5" : "e7101aca7567b7dde838c0489ad51334", "matches" : [ { "signature" : { "accession" : "PS51257", "name" : "PROKAR_LIPOPROTEIN", "description" : "Prokaryotic membrane lipoprotein lipid attachment site profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 15, "score" : 5.0, "alignment" : "MDKE--------------------QIILFAGITGC", "location-fragments" : [ { "start" : 1, "end" : 15, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51257" }, { "signature" : { "accession" : "SSF54001", "name" : "Cysteine proteinases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR038765", "name" : "Papain-like_cys_pep_sf", "description" : "Papain-like cysteine peptidase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 34, "end" : 449, "hmmLength" : 397, "location-fragments" : [ { "start" : 207, "end" : 449, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 34, "end" : 136, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 7.85E-69, "model-ac" : "0044814" }, { "signature" : { "accession" : "PS00973", "name" : "USP_2", "description" : "Ubiquitin specific protease (USP) domain signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018200", "name" : "USP_CS", "description" : "Ubiquitin specific protease, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "thiol-dependent ubiquitinyl hydrolase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0036459" }, { "name" : "ubiquitin-dependent protein catabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006511" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 377, "end" : 395, "level" : "STRONG", "cigarAlignment" : "1M1I1M1I2M2I1M1I1M5I3M", "alignment" : "YrLkAVivHcGssewgGHF", "location-fragments" : [ { "start" : 377, "end" : 395, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00973" }, { "signature" : { "accession" : "cd02662", "name" : "Peptidase_C19F", "description" : "Peptidase_C19F", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 39, "end" : 447, "sites" : [ { "description" : "Active Site", "numLocations" : 4, "siteLocations" : [ { "start" : 42, "end" : 42, "residue" : "N" }, { "start" : 394, "end" : 394, "residue" : "H" }, { "start" : 425, "end" : 425, "residue" : "D" }, { "start" : 47, "end" : 47, "residue" : "C" } ] } ], "evalue" : 3.06274E-50, "score" : 169.084, "location-fragments" : [ { "start" : 39, "end" : 447, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd02662" }, { "signature" : { "accession" : "PTHR24006", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 447, "hmmStart" : 29, "hmmEnd" : 384, "hmmLength" : 385, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 448, "location-fragments" : [ { "start" : 18, "end" : 447, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.9E-69, "familyName" : "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30", "score" : 235.3, "model-ac" : "PTHR24006" }, { "signature" : { "accession" : "PTHR24006:SF764", "name" : "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 18, "end" : 447, "hmmStart" : 29, "hmmEnd" : 384, "hmmLength" : 385, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 3, "envelopeEnd" : 448, "location-fragments" : [ { "start" : 18, "end" : 447, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.9E-69, "familyName" : "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30", "score" : 235.3, "model-ac" : "PTHR24006:SF764" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 152, "end" : 172, "location-fragments" : [ { "start" : 152, "end" : 172, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00443", "name" : "UCH", "description" : "Ubiquitin carboxyl-terminal hydrolase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001394", "name" : "Peptidase_C19_UCH", "description" : "Peptidase C19, ubiquitin carboxyl-terminal hydrolase", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein deubiquitination", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0016579" }, { "name" : "thiol-dependent ubiquitinyl hydrolase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0036459" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 38, "end" : 446, "hmmStart" : 1, "hmmEnd" : 269, "hmmLength" : 269, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-35, "score" : 122.9, "envelopeStart" : 38, "envelopeEnd" : 446, "postProcessed" : true, "location-fragments" : [ { "start" : 38, "end" : 446, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.7E-36, "score" : 123.8, "model-ac" : "PF00443" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 152, "end" : 167, "location-fragments" : [ { "start" : 152, "end" : 167, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50235", "name" : "USP_3", "description" : "Ubiquitin specific protease (USP) domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR028889", "name" : "USP_dom", "description" : "Ubiquitin specific protease domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 38, "end" : 449, "score" : 36.885, "alignment" : "VGLRNLGMTCFLNTVLQSLASCSFFVEWSV----SLPRKGNLTQTIEKILRILNgevNGVDIPYSPIEIVSA-IRKHGWTMPHSEHDAHEFFHVVLTSIEEEITKnsplrksclldvleeepssteekhqdhgdtppdtqnisivenKIIVSNGDIAPTRSFACINKTSLSLVDKSKPSPFKGFLTSQLKCTGCGFVsPLRYDPFDSISLHLPSASS---VLTHYSLTQLLDKFVETEQVEGVECEGCNKNRAETTpvisteALKTLRFGKLPKCLCFHISRLTMQsNGTTYKRQDTVEFSEYLTMDPYTHNTLikknisnnkisketnesngsirpEDIPECKNHLYRLKAVIVHCGSsEWGGHFITYRHGYLrsqtrhrckdsrnNPRWFYTSDEEVRQTSLAEVLSSLPYMLFYEKC", "location-fragments" : [ { "start" : 38, "end" : 449, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50235" } ], "xref" : [ { "name" : "XP_018909601.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase 30 homolog isoform X1 [Bemisia tabaci]", "id" : "XP_018909601.1" } ] },{ "sequence" : "MMSPNSIILLDIEGTITSKRFVTDTLFPYVRQHLSEYLTSYWNQEELKRDITALKEQAETDKKTGFADFVPIPSEGTSDEVREAVIRNVLRQMDLDRKTTGLKSLQGHMWKYGYDSGKIVGHVYSDAFEAIKKWAAEKKKIMIYSSGSIEAQKLLFRFSEHGDMTPYFCAHFDTTIGSKKEKTSYERIARECQARTADFTFYTDSVEEAHAATMAGMNVILVQRPEDEPGDASVIPDVKIIQNFKDALFS", "md5" : "5cf8baf52b5bc06603e5de6fbe911649", "matches" : [ { "signature" : { "accession" : "cd01629", "name" : "HAD_EP", "description" : "HAD_EP", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR023943", "name" : "Enolase-ppase_E1", "description" : "Enolase-phosphatase E1", "type" : "FAMILY", "goXRefs" : [ { "name" : "L-methionine salvage from methylthioadenosine", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0019509" }, { "name" : "acireductone synthase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0043874" }, { "name" : "magnesium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0000287" } ], "pathwayXRefs" : [ { "name" : "Methionine salvage pathway", "databaseName" : "Reactome", "id" : "R-HSA-1237112" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+3.1.3.77" } ] } }, "locations" : [ { "start" : 8, "end" : 225, "sites" : [ { "description" : "HAD signature motif III", "numLocations" : 1, "siteLocations" : [ { "start" : 179, "end" : 179, "residue" : "K" } ] }, { "description" : "active site", "numLocations" : 18, "siteLocations" : [ { "start" : 26, "end" : 26, "residue" : "L" }, { "start" : 22, "end" : 22, "residue" : "V" }, { "start" : 203, "end" : 203, "residue" : "T" }, { "start" : 12, "end" : 12, "residue" : "I" }, { "start" : 209, "end" : 209, "residue" : "A" }, { "start" : 15, "end" : 15, "residue" : "T" }, { "start" : 146, "end" : 146, "residue" : "S" }, { "start" : 110, "end" : 110, "residue" : "W" }, { "start" : 208, "end" : 208, "residue" : "E" }, { "start" : 11, "end" : 11, "residue" : "D" }, { "start" : 145, "end" : 145, "residue" : "S" }, { "start" : 204, "end" : 204, "residue" : "D" }, { "start" : 13, "end" : 13, "residue" : "E" }, { "start" : 151, "end" : 151, "residue" : "A" }, { "start" : 179, "end" : 179, "residue" : "K" }, { "start" : 27, "end" : 27, "residue" : "F" }, { "start" : 14, "end" : 14, "residue" : "G" }, { "start" : 147, "end" : 147, "residue" : "G" } ] }, { "description" : "HAD signature motif II", "numLocations" : 1, "siteLocations" : [ { "start" : 145, "end" : 145, "residue" : "S" } ] }, { "description" : "HAD signature motif IV", "numLocations" : 3, "siteLocations" : [ { "start" : 203, "end" : 203, "residue" : "T" }, { "start" : 204, "end" : 204, "residue" : "D" }, { "start" : 208, "end" : 208, "residue" : "E" } ] }, { "description" : "HAD signature motif I", "numLocations" : 5, "siteLocations" : [ { "start" : 11, "end" : 11, "residue" : "D" }, { "start" : 12, "end" : 12, "residue" : "I" }, { "start" : 13, "end" : 13, "residue" : "E" }, { "start" : 15, "end" : 15, "residue" : "T" }, { "start" : 14, "end" : 14, "residue" : "G" } ] } ], "evalue" : 5.11111E-95, "score" : 275.19, "location-fragments" : [ { "start" : 8, "end" : 225, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01629" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 44, "end" : 64, "location-fragments" : [ { "start" : 44, "end" : 64, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "SSF56784", "name" : "HAD-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036412", "name" : "HAD-like_sf", "description" : "HAD-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 246, "hmmLength" : 253, "location-fragments" : [ { "start" : 1, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.04E-50, "model-ac" : "0051632" }, { "signature" : { "accession" : "PTHR20371", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 246, "hmmStart" : 12, "hmmEnd" : 255, "hmmLength" : 258, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 248, "location-fragments" : [ { "start" : 3, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.1E-87, "familyName" : "ENOLASE-PHOSPHATASE E1", "score" : 293.9, "model-ac" : "PTHR20371" }, { "signature" : { "accession" : "PTHR20371:SF1", "name" : "ENOLASE-PHOSPHATASE E1", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 3, "end" : 246, "hmmStart" : 12, "hmmEnd" : 255, "hmmLength" : 258, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 248, "location-fragments" : [ { "start" : 3, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.1E-87, "familyName" : "ENOLASE-PHOSPHATASE E1", "score" : 293.9, "model-ac" : "PTHR20371:SF1" }, { "signature" : { "accession" : "SFLDG01129", "name" : "C1.5:_HAD,_Beta-PGM,_Phosphat", "description" : "C1.5: HAD, Beta-PGM, Phosphatase Like", "signatureLibraryRelease" : { "library" : "SFLD", "version" : "4" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 246, "sites" : [ { "description" : " ", "numLocations" : 1, "siteLocations" : [ { "start" : 179, "end" : 179, "residue" : "K" } ] }, { "description" : " Mg2+ ligand, nucleophile: attacks phosphate moiety of intermediate to form covalent intermediate", "numLocations" : 1, "siteLocations" : [ { "start" : 11, "end" : 11, "residue" : "D" } ] } ], "hmmStart" : 5, "hmmEnd" : 230, "hmmLength" : 220, "evalue" : 0.0, "score" : 259.8, "envelopeStart" : 3, "envelopeEnd" : 249, "location-fragments" : [ { "start" : 7, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "score" : 260.0, "model-ac" : "SFLDG01129" }, { "signature" : { "accession" : "TIGR01691", "name" : "TIGR01691", "description" : "enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR023943", "name" : "Enolase-ppase_E1", "description" : "Enolase-phosphatase E1", "type" : "FAMILY", "goXRefs" : [ { "name" : "L-methionine salvage from methylthioadenosine", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0019509" }, { "name" : "acireductone synthase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0043874" }, { "name" : "magnesium ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0000287" } ], "pathwayXRefs" : [ { "name" : "Methionine salvage pathway", "databaseName" : "Reactome", "id" : "R-HSA-1237112" }, { "name" : "Cysteine and methionine metabolism", "databaseName" : "KEGG", "id" : "00270+3.1.3.77" } ] } }, "locations" : [ { "start" : 7, "end" : 246, "hmmStart" : 3, "hmmEnd" : 223, "hmmLength" : 224, "hmmBounds" : "INCOMPLETE", "evalue" : 4.9E-61, "score" : 204.0, "envelopeStart" : 6, "envelopeEnd" : 247, "postProcessed" : false, "location-fragments" : [ { "start" : 7, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-62, "score" : 209.3, "model-ac" : "TIGR01691" }, { "signature" : { "accession" : "G3DSA:3.40.50.1000", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR023214", "name" : "HAD_sf", "description" : "HAD superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 8, "end" : 229, "hmmStart" : 2, "hmmEnd" : 226, "hmmLength" : 157, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-85, "score" : 288.4, "envelopeStart" : 7, "envelopeEnd" : 239, "postProcessed" : true, "location-fragments" : [ { "start" : 8, "end" : 18, "dc-status" : "C_TERMINAL_DISC" }, { "start" : 120, "end" : 229, "dc-status" : "N_TERMINAL_DISC" } ] } ], "evalue" : 1.3E-85, "score" : 288.7, "model-ac" : "1ynsA01" }, { "signature" : { "accession" : "SFLDF00044", "name" : "enolase-phosphatase", "description" : "enolase-phosphatase", "signatureLibraryRelease" : { "library" : "SFLD", "version" : "4" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 246, "sites" : [ { "description" : " ", "numLocations" : 1, "siteLocations" : [ { "start" : 15, "end" : 15, "residue" : "T" } ] }, { "description" : " Mg2+ ligand", "numLocations" : 1, "siteLocations" : [ { "start" : 204, "end" : 204, "residue" : "D" } ] }, { "description" : " binds phosphate moiety of substrate to increase elecrophilicity and facilitate nucleophilic attack", "numLocations" : 1, "siteLocations" : [ { "start" : 146, "end" : 146, "residue" : "S" } ] }, { "description" : " nucleophile: attacks phosphate moiety of substrate to form covalent intermediate; Mg2+ ligand", "numLocations" : 1, "siteLocations" : [ { "start" : 11, "end" : 11, "residue" : "D" } ] }, { "description" : " Mg2+ ligand (via water)", "numLocations" : 1, "siteLocations" : [ { "start" : 208, "end" : 208, "residue" : "E" } ] }, { "description" : " Forms salt bridge with nucleophilic Asp; binds phosphate moiety of substrate to increase elecrophilicity and facilitate nucleophilic attack", "numLocations" : 1, "siteLocations" : [ { "start" : 179, "end" : 179, "residue" : "K" } ] } ], "hmmStart" : 5, "hmmEnd" : 230, "hmmLength" : 233, "evalue" : 0.0, "score" : 259.8, "envelopeStart" : 3, "envelopeEnd" : 249, "location-fragments" : [ { "start" : 7, "end" : 246, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "score" : 260.0, "model-ac" : "SFLDF00044" }, { "signature" : { "accession" : "G3DSA:1.10.720.60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 119, "hmmStart" : 2, "hmmEnd" : 226, "hmmLength" : 235, "hmmBounds" : "INCOMPLETE", "evalue" : 1.6E-85, "score" : 288.4, "envelopeStart" : 7, "envelopeEnd" : 239, "postProcessed" : true, "location-fragments" : [ { "start" : 19, "end" : 119, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-85, "score" : 288.7, "model-ac" : "1ynsA02" } ], "xref" : [ { "name" : "XP_018909922.1 PREDICTED: enolase-phosphatase E1 [Bemisia tabaci]", "id" : "XP_018909922.1" } ] },{ "sequence" : "MDGVGAPEIIMRNRVNGTFLSQNVGKPISIIGSILKMNPSNNGFDIQTTDNHVVSVSCKEMISECLDGLVEVRGIAEGKNSVTCDYYILFPRELASTFDTEKDNEAVMIVNSIPNAFKA", "md5" : "200316080fba355c7a65052c92c0819e", "matches" : [ { "signature" : { "accession" : "SSF50249", "name" : "Nucleic acid-binding proteins", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR012340", "name" : "NA-bd_OB-fold", "description" : "Nucleic acid-binding, OB-fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 12, "end" : 117, "hmmLength" : 114, "location-fragments" : [ { "start" : 12, "end" : 117, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-11, "model-ac" : "0043001" }, { "signature" : { "accession" : "PF08661", "name" : "Rep_fac-A_3", "description" : "Replication factor A protein 3", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013970", "name" : "Rfa2", "description" : "Replication factor A protein 3", "type" : "FAMILY", "goXRefs" : [ { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" }, { "name" : "DNA replication", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006260" }, { "name" : "DNA repair", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006281" }, { "name" : "DNA binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003677" }, { "name" : "DNA recombination", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006310" } ], "pathwayXRefs" : [ { "name" : "Regulation of TP53 Activity through Phosphorylation", "databaseName" : "Reactome", "id" : "R-HSA-6804756" }, { "name" : "Processing of DNA double-strand break ends", "databaseName" : "Reactome", "id" : "R-HSA-5693607" }, { "name" : "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)", "databaseName" : "Reactome", "id" : "R-HSA-5358606" }, { "name" : "HDR through Single Strand Annealing (SSA)", "databaseName" : "Reactome", "id" : "R-HSA-5685938" }, { "name" : "Removal of the Flap Intermediate from the C-strand", "databaseName" : "Reactome", "id" : "R-HSA-174437" }, { "name" : "Gap-filling DNA repair synthesis and ligation in GG-NER", "databaseName" : "Reactome", "id" : "R-HSA-5696397" }, { "name" : "Termination of translesion DNA synthesis", "databaseName" : "Reactome", "id" : "R-HSA-5656169" }, { "name" : "HSF1 activation", "databaseName" : "Reactome", "id" : "R-HSA-3371511" }, { "name" : "Activation of ATR in response to replication stress", "databaseName" : "Reactome", "id" : "R-HSA-176187" }, { "name" : "HDR through Homologous Recombination (HRR)", "databaseName" : "Reactome", "id" : "R-HSA-5685942" }, { "name" : "Dual incision in TC-NER", "databaseName" : "Reactome", "id" : "R-HSA-6782135" }, { "name" : "Dual Incision in GG-NER", "databaseName" : "Reactome", "id" : "R-HSA-5696400" }, { "name" : "Gap-filling DNA repair synthesis and ligation in TC-NER", "databaseName" : "Reactome", "id" : "R-HSA-6782210" }, { "name" : "Translesion Synthesis by POLH", "databaseName" : "Reactome", "id" : "R-HSA-110320" }, { "name" : "Presynaptic phase of homologous DNA pairing and strand exchange", "databaseName" : "Reactome", "id" : "R-HSA-5693616" }, { "name" : "Translesion synthesis by REV1", "databaseName" : "Reactome", "id" : "R-HSA-110312" }, { "name" : "Recognition of DNA damage by PCNA-containing replication complex", "databaseName" : "Reactome", "id" : "R-HSA-110314" }, { "name" : "Meiotic recombination", "databaseName" : "Reactome", "id" : "R-HSA-912446" }, { "name" : "Formation of Incision Complex in GG-NER", "databaseName" : "Reactome", "id" : "R-HSA-5696395" }, { "name" : "Activation of the pre-replicative complex", "databaseName" : "Reactome", "id" : "R-HSA-68962" }, { "name" : "PCNA-Dependent Long Patch Base Excision Repair", "databaseName" : "Reactome", "id" : "R-HSA-5651801" }, { "name" : "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)", "databaseName" : "Reactome", "id" : "R-HSA-5358565" }, { "name" : "G2/M DNA damage checkpoint", "databaseName" : "Reactome", "id" : "R-HSA-69473" }, { "name" : "Translesion synthesis by POLK", "databaseName" : "Reactome", "id" : "R-HSA-5655862" }, { "name" : "Removal of the Flap Intermediate", "databaseName" : "Reactome", "id" : "R-HSA-69166" }, { "name" : "Fanconi Anemia Pathway", "databaseName" : "Reactome", "id" : "R-HSA-6783310" }, { "name" : "Translesion synthesis by POLI", "databaseName" : "Reactome", "id" : "R-HSA-5656121" }, { "name" : "Regulation of HSF1-mediated heat shock response", "databaseName" : "Reactome", "id" : "R-HSA-3371453" } ] } }, "locations" : [ { "start" : 12, "end" : 117, "hmmStart" : 5, "hmmEnd" : 105, "hmmLength" : 105, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.9E-14, "score" : 53.3, "envelopeStart" : 8, "envelopeEnd" : 117, "postProcessed" : true, "location-fragments" : [ { "start" : 12, "end" : 117, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.5E-14, "score" : 53.5, "model-ac" : "PF08661" }, { "signature" : { "accession" : "PTHR15114", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 117, "hmmStart" : 13, "hmmEnd" : 115, "hmmLength" : 122, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 119, "location-fragments" : [ { "start" : 12, "end" : 117, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-16, "familyName" : "FAMILY NOT NAMED", "score" : 63.3, "model-ac" : "PTHR15114" }, { "signature" : { "accession" : "G3DSA:2.40.50.140", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 8, "end" : 119, "hmmStart" : 8, "hmmEnd" : 114, "hmmLength" : 121, "hmmBounds" : "COMPLETE", "evalue" : 2.4E-33, "score" : 116.4, "envelopeStart" : 8, "envelopeEnd" : 119, "postProcessed" : true, "location-fragments" : [ { "start" : 8, "end" : 119, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-33, "score" : 116.7, "model-ac" : "3kdfA00" } ], "xref" : [ { "name" : "XP_018910528.1 PREDICTED: uncharacterized protein LOC109039493 [Bemisia tabaci]", "id" : "XP_018910528.1" } ] },{ "sequence" : "MKILREEKGSGVFCRVQAFVFGILLNCNLFLAAGRGPTQLRKALTVDYFENCEQKVYPVRTNFSFARNGSLIIINGEEIIERDSKDIISILFRIEKCKDKSNPDTCEYYTTWKFDNFCGLKVMPFYSLVMEAHTPPMTCPLKKGRYAVKDAKIESGLVAQFLGRGESSRVLWKYHIVMRENNQPITCINLGFRIVDVRIRH", "md5" : "7bc565212f35c747fa3aaccd575c1772", "matches" : [ ], "xref" : [ { "name" : "XP_018909600.1 PREDICTED: uncharacterized protein LOC109038836 [Bemisia tabaci]", "id" : "XP_018909600.1" } ] },{ "sequence" : "MFPAKSKSGQPAAKFGRRGVLMINAPSPLEWCEEQMMSGDMGIFASRAGPNACWHPACFVCCVCKELLVDLIYFWRANKLYCGRHHAETLKPRCSACDEIILADECTEAEGRAWHMKHFACLECDRQLGGQRYIMRDGRPYCLHCFDAMFAEYCDSCGEPIGVDHGQMSHEGQHWHATEQCFCCHTCRAALLGRPFERSSIVDIGRSRIRKKGSRRLEANGSNGSANCRECHEHSPGRVRTSLLLFLIKLTPFEDISNSKVIVHLPIY", "md5" : "b2909de3ac67df1a7496d7be40a06ebe", "matches" : [ { "signature" : { "accession" : "PS00478", "name" : "LIM_DOMAIN_1", "description" : "LIM zinc-binding domain signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR001781", "name" : "Znf_LIM", "description" : "Zinc finger, LIM-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 94, "end" : 128, "level" : "STRONG", "cigarAlignment" : "1M2I1M16I2M2I1M2I1M2I1M3I1M", "alignment" : "CsaCdeiiladecteaegraWHmkHfaCleCdrqL", "location-fragments" : [ { "start" : 94, "end" : 128, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00478" }, { "signature" : { "accession" : "PS50023", "name" : "LIM_DOMAIN_2", "description" : "LIM domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001781", "name" : "Znf_LIM", "description" : "Zinc finger, LIM-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 92, "end" : 152, "score" : 13.83, "alignment" : "PRCSACDEIILADECTEAEGRAWHMKHFACLECDRQLGGQRYIMRDGRPYCLHCFDAMFAE", "location-fragments" : [ { "start" : 92, "end" : 152, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50023" }, { "signature" : { "accession" : "SSF57716", "name" : "Glucocorticoid receptor-like (DNA-binding domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 61, "end" : 125, "hmmLength" : 65, "location-fragments" : [ { "start" : 61, "end" : 125, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.55E-15, "model-ac" : "0035409" }, { "signature" : { "accession" : "PTHR24211", "name" : "LIM DOMAIN-CONTAINING PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 198, "hmmStart" : 164, "hmmEnd" : 346, "hmmLength" : 698, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 11, "envelopeEnd" : 242, "location-fragments" : [ { "start" : 16, "end" : 198, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-115, "familyName" : "PROTEIN ESPINAS-RELATED", "score" : 389.9, "model-ac" : "PTHR24211" }, { "signature" : { "accession" : "PS50023", "name" : "LIM_DOMAIN_2", "description" : "LIM domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001781", "name" : "Znf_LIM", "description" : "Zinc finger, LIM-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 27, "end" : 91, "score" : 7.673, "alignment" : "SPLEWCEEQMMSGDmgifaSRAGPNACWHPACFVCCVCKELLVDLIYFWRANKLYCGRHHAETL-K", "location-fragments" : [ { "start" : 27, "end" : 91, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50023" }, { "signature" : { "accession" : "PF00412", "name" : "LIM", "description" : "LIM domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001781", "name" : "Znf_LIM", "description" : "Zinc finger, LIM-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 49, "end" : 88, "hmmStart" : 17, "hmmEnd" : 56, "hmmLength" : 58, "hmmBounds" : "INCOMPLETE", "evalue" : 9.4E-10, "score" : 38.6, "envelopeStart" : 31, "envelopeEnd" : 90, "postProcessed" : true, "location-fragments" : [ { "start" : 49, "end" : 88, "dc-status" : "CONTINUOUS" } ] }, { "start" : 94, "end" : 148, "hmmStart" : 1, "hmmEnd" : 56, "hmmLength" : 58, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.1E-13, "score" : 50.3, "envelopeStart" : 94, "envelopeEnd" : 150, "postProcessed" : true, "location-fragments" : [ { "start" : 94, "end" : 148, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-26, "score" : 92.8, "model-ac" : "PF00412" }, { "signature" : { "accession" : "PTHR24211:SF20", "name" : "PROTEIN ESPINAS-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 16, "end" : 198, "hmmStart" : 164, "hmmEnd" : 346, "hmmLength" : 698, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 11, "envelopeEnd" : 242, "location-fragments" : [ { "start" : 16, "end" : 198, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-115, "familyName" : "PROTEIN ESPINAS-RELATED", "score" : 389.9, "model-ac" : "PTHR24211:SF20" }, { "signature" : { "accession" : "G3DSA:2.10.110.10", "name" : "Cysteine Rich Protein", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 147, "end" : 201, "hmmStart" : 8, "hmmEnd" : 58, "hmmLength" : 82, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.2E-12, "score" : 47.6, "envelopeStart" : 143, "envelopeEnd" : 201, "postProcessed" : true, "location-fragments" : [ { "start" : 147, "end" : 201, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-32, "score" : 113.3, "model-ac" : "2eheA00" }, { "signature" : { "accession" : "G3DSA:2.10.110.10", "name" : "Cysteine Rich Protein", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 91, "end" : 146, "hmmStart" : 3, "hmmEnd" : 59, "hmmLength" : 63, "hmmBounds" : "INCOMPLETE", "evalue" : 3.1E-18, "score" : 67.6, "envelopeStart" : 89, "envelopeEnd" : 150, "postProcessed" : true, "location-fragments" : [ { "start" : 91, "end" : 146, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-35, "score" : 121.0, "model-ac" : "2xqnT01" }, { "signature" : { "accession" : "cd09418", "name" : "LIM2_Prickle", "description" : "LIM2_Prickle", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR033726", "name" : "LIM2_prickle", "description" : "LIM2 prickle", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 92, "end" : 147, "sites" : [ { "description" : "Zn binding site", "numLocations" : 8, "siteLocations" : [ { "start" : 94, "end" : 94, "residue" : "C" }, { "start" : 142, "end" : 142, "residue" : "C" }, { "start" : 124, "end" : 124, "residue" : "C" }, { "start" : 97, "end" : 97, "residue" : "C" }, { "start" : 121, "end" : 121, "residue" : "C" }, { "start" : 145, "end" : 145, "residue" : "C" }, { "start" : 118, "end" : 118, "residue" : "H" }, { "start" : 115, "end" : 115, "residue" : "H" } ] } ], "evalue" : 1.449E-32, "score" : 111.75, "location-fragments" : [ { "start" : 92, "end" : 147, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd09418" }, { "signature" : { "accession" : "SSF57716", "name" : "Glucocorticoid receptor-like (DNA-binding domain)", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 121, "end" : 187, "hmmLength" : 65, "location-fragments" : [ { "start" : 121, "end" : 187, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.48E-14, "model-ac" : "0035409" }, { "signature" : { "accession" : "SM00132", "name" : "lim_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001781", "name" : "Znf_LIM", "description" : "Zinc finger, LIM-type", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 32, "end" : 85, "hmmStart" : 1, "hmmEnd" : 52, "hmmLength" : 52, "hmmBounds" : "COMPLETE", "evalue" : 4.8E-5, "score" : 32.8, "location-fragments" : [ { "start" : 32, "end" : 85, "dc-status" : "CONTINUOUS" } ] }, { "start" : 93, "end" : 145, "hmmStart" : 1, "hmmEnd" : 52, "hmmLength" : 52, "hmmBounds" : "COMPLETE", "evalue" : 2.1E-16, "score" : 70.5, "location-fragments" : [ { "start" : 93, "end" : 145, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-26, "score" : 103.2, "model-ac" : "SM00132" }, { "signature" : { "accession" : "G3DSA:2.10.110.10", "name" : "Cysteine Rich Protein", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 90, "hmmStart" : 19, "hmmEnd" : 72, "hmmLength" : 80, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.8E-11, "score" : 45.8, "envelopeStart" : 19, "envelopeEnd" : 92, "postProcessed" : true, "location-fragments" : [ { "start" : 19, "end" : 90, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-31, "score" : 109.9, "model-ac" : "2dj7A00" } ], "xref" : [ { "name" : "XP_018910216.1 PREDICTED: protein prickle-like [Bemisia tabaci]", "id" : "XP_018910216.1" } ] },{ "sequence" : "MSNQSARSLNFTGAEKEKILEIGMEYYDLLHSPLNNSVTMAEKNRIYQLMAEEVNKVGLNSRSVKQIKKKYQELIQNATRKQRIITTERKRTGNKRMRVSLDHLDEEIIRKVPPMKYIGISGGVDSSAEGTHYCNVWDEVQQGDTPDEEVQPTDTPDEEEASGGDGKMTDKRHFQRNGCP", "md5" : "48139c0841bbb1140fd52348585bd93f", "matches" : [ { "signature" : { "accession" : "PTHR23098", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR026753", "name" : "NAIF1", "description" : "Nuclear apoptosis-inducing factor 1", "type" : "FAMILY", "goXRefs" : [ { "name" : "nucleus", "databaseName" : "GO", "category" : "CELLULAR_COMPONENT", "id" : "GO:0005634" }, { "name" : "apoptotic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006915" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 160, "hmmStart" : 58, "hmmEnd" : 211, "hmmLength" : 373, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 177, "location-fragments" : [ { "start" : 7, "end" : 160, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.6E-12, "familyName" : "FAMILY NOT NAMED", "score" : 47.8, "model-ac" : "PTHR23098" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 142, "end" : 159, "location-fragments" : [ { "start" : 142, "end" : 159, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 160, "end" : 174, "location-fragments" : [ { "start" : 160, "end" : 174, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF13873", "name" : "Myb_DNA-bind_5", "description" : "Myb/SANT-like DNA-binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR028002", "name" : "Myb_DNA-bind_5", "description" : "Myb/SANT-like DNA-binding domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 81, "hmmStart" : 1, "hmmEnd" : 75, "hmmLength" : 78, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.8E-10, "score" : 39.6, "envelopeStart" : 7, "envelopeEnd" : 84, "postProcessed" : true, "location-fragments" : [ { "start" : 7, "end" : 81, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-10, "score" : 40.4, "model-ac" : "PF13873" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 138, "end" : 180, "location-fragments" : [ { "start" : 138, "end" : 180, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 64, "end" : 84, "location-fragments" : [ { "start" : 64, "end" : 84, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" } ], "xref" : [ { "name" : "XP_018910445.1 PREDICTED: uncharacterized protein LOC109039430 [Bemisia tabaci]", "id" : "XP_018910445.1" } ] },{ "sequence" : "MYARSQQRNFTKMPVTGGTPVTQEVAIAFRSIVFGTSVAPPRGEWLRTGFVFRDADKELAYGLKAPRNGCRGLLSVVQAYILKQLLFERKDFKKNEPVMQPEMLLRPSRGKQLEALWLAISDILWRIGEKTKAVVCLPQDQPYVSHSLNYFQDSVTEKLHIFEIANLEELQIFIKRYIHLFLEEPGPGALLLLYSAVATRGTKNVISDIMDEKGYLVTGAEEGSQSIIMLLLTGRATPYLHNGVVYVGDEEHYAIPQFGVLQRSEIGFLLFDEGVEEKAPGSRLKTPSLPIWVVCCLGHFGVIFNTNRELLRNYHAERRFELIYYTCGGSQCQLTVDTRHDGSSTQVSTSEDTASSSLANLEKLIHTKWQDAHIHWNGTSNFI", "md5" : "918d81e70699793c41bd77708293e2b5", "matches" : [ { "signature" : { "accession" : "PTHR12473", "name" : "UNCHARACTERIZED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR039785", "name" : "MINY3/4", "description" : "Deubiquitinating enzyme MINDY-3/4", "type" : "FAMILY", "goXRefs" : [ { "name" : "Lys48-specific deubiquitinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:1990380" }, { "name" : "protein K48-linked deubiquitination", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0071108" }, { "name" : "thiol-dependent ubiquitin-specific protease activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004843" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 380, "hmmStart" : 187, "hmmEnd" : 549, "hmmLength" : 552, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 383, "location-fragments" : [ { "start" : 7, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-104, "familyName" : "", "score" : 352.9, "model-ac" : "PTHR12473" }, { "signature" : { "accession" : "PTHR12473:SF4", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 7, "end" : 380, "hmmStart" : 187, "hmmEnd" : 549, "hmmLength" : 552, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 383, "location-fragments" : [ { "start" : 7, "end" : 380, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-104, "familyName" : "", "score" : 352.9, "model-ac" : "PTHR12473:SF4" }, { "signature" : { "accession" : "SM01174", "name" : "DUF4205_3", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR025257", "name" : "MINDY-3/4_CD", "description" : "Deubiquitinating enzyme MINDY-3/4, conserved domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 30, "end" : 378, "hmmStart" : 1, "hmmEnd" : 438, "hmmLength" : 438, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-131, "score" : 452.1, "location-fragments" : [ { "start" : 30, "end" : 378, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.9E-131, "score" : 452.1, "model-ac" : "SM01174" }, { "signature" : { "accession" : "PF13898", "name" : "DUF4205", "description" : "Domain of unknown function (DUF4205)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR025257", "name" : "MINDY-3/4_CD", "description" : "Deubiquitinating enzyme MINDY-3/4, conserved domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 30, "end" : 378, "hmmStart" : 1, "hmmEnd" : 351, "hmmLength" : 351, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-129, "score" : 432.4, "envelopeStart" : 30, "envelopeEnd" : 378, "postProcessed" : true, "location-fragments" : [ { "start" : 30, "end" : 378, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.3E-130, "score" : 432.6, "model-ac" : "PF13898" } ], "xref" : [ { "name" : "XP_018910122.1 PREDICTED: protein FAM188B2 isoform X6 [Bemisia tabaci]", "id" : "XP_018910122.1" }, { "name" : "XP_018910123.1 PREDICTED: protein FAM188B2 isoform X6 [Bemisia tabaci]", "id" : "XP_018910123.1" } ] },{ "sequence" : "MQVGDQIPCAELYEDTPANKINIAEYVKGKKIVLFAVPGAFTPGCSKTHLPGYVADADKLKSKGISEIICVSVNDPFVMGAWGKDQNVNGKVKLLADPSAAFTKALELDTDIPPLGGTRSKRYSMVIDDGKVTQLNVEPDGTGLSCSLSKSLNV", "md5" : "2f9764e48e22a46ee5e8c2237dcec7ed", "matches" : [ { "signature" : { "accession" : "PTHR10430:SF16", "name" : "PEROXIREDOXIN-5, MITOCHONDRIAL", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 150, "hmmStart" : 17, "hmmEnd" : 172, "hmmLength" : 178, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 153, "location-fragments" : [ { "start" : 2, "end" : 150, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-58, "familyName" : "PEROXIREDOXIN-5, MITOCHONDRIAL", "score" : 197.5, "model-ac" : "PTHR10430:SF16" }, { "signature" : { "accession" : "cd03013", "name" : "PRX5_like", "description" : "PRX5_like", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR037944", "name" : "PRX5-like", "description" : "Peroxiredoxin-5-like", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Glutathione metabolism", "databaseName" : "KEGG", "id" : "00480+1.11.1.15" }, { "name" : "Detoxification of Reactive Oxygen Species", "databaseName" : "Reactome", "id" : "R-HSA-3299685" }, { "name" : "TP53 Regulates Metabolic Genes", "databaseName" : "Reactome", "id" : "R-HSA-5628897" } ] } }, "locations" : [ { "start" : 3, "end" : 147, "sites" : [ { "description" : "catalytic triad", "numLocations" : 3, "siteLocations" : [ { "start" : 42, "end" : 42, "residue" : "T" }, { "start" : 122, "end" : 122, "residue" : "R" }, { "start" : 45, "end" : 45, "residue" : "C" } ] }, { "description" : "dimer interface", "numLocations" : 6, "siteLocations" : [ { "start" : 99, "end" : 99, "residue" : "S" }, { "start" : 75, "end" : 75, "residue" : "D" }, { "start" : 43, "end" : 43, "residue" : "P" }, { "start" : 77, "end" : 77, "residue" : "F" }, { "start" : 119, "end" : 119, "residue" : "R" }, { "start" : 98, "end" : 98, "residue" : "P" } ] } ], "evalue" : 8.81155E-76, "score" : 220.897, "location-fragments" : [ { "start" : 3, "end" : 147, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd03013" }, { "signature" : { "accession" : "PTHR10430", "name" : "PEROXIREDOXIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR037944", "name" : "PRX5-like", "description" : "Peroxiredoxin-5-like", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Glutathione metabolism", "databaseName" : "KEGG", "id" : "00480+1.11.1.15" }, { "name" : "Detoxification of Reactive Oxygen Species", "databaseName" : "Reactome", "id" : "R-HSA-3299685" }, { "name" : "TP53 Regulates Metabolic Genes", "databaseName" : "Reactome", "id" : "R-HSA-5628897" } ] } }, "locations" : [ { "start" : 2, "end" : 150, "hmmStart" : 17, "hmmEnd" : 172, "hmmLength" : 178, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 153, "location-fragments" : [ { "start" : 2, "end" : 150, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.4E-58, "familyName" : "PEROXIREDOXIN-5, MITOCHONDRIAL", "score" : 197.5, "model-ac" : "PTHR10430" }, { "signature" : { "accession" : "PF08534", "name" : "Redoxin", "description" : "Redoxin", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR013740", "name" : "Redoxin", "description" : "Redoxin", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" } ], "pathwayXRefs" : [ { "name" : "TP53 Regulates Metabolic Genes", "databaseName" : "Reactome", "id" : "R-HSA-5628897" }, { "name" : "Detoxification of Reactive Oxygen Species", "databaseName" : "Reactome", "id" : "R-HSA-3299685" } ] } }, "locations" : [ { "start" : 2, "end" : 142, "hmmStart" : 1, "hmmEnd" : 137, "hmmLength" : 147, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.1E-34, "score" : 119.2, "envelopeStart" : 2, "envelopeEnd" : 152, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 142, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 9.9E-35, "score" : 119.4, "model-ac" : "PF08534" }, { "signature" : { "accession" : "G3DSA:3.40.30.10", "name" : "Glutaredoxin", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036249", "name" : "Thioredoxin-like_sf", "description" : "Thioredoxin-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 153, "hmmStart" : 15, "hmmEnd" : 163, "hmmLength" : 171, "hmmBounds" : "COMPLETE", "evalue" : 9.4E-62, "score" : 208.9, "envelopeStart" : 1, "envelopeEnd" : 153, "postProcessed" : true, "location-fragments" : [ { "start" : 1, "end" : 153, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.9E-62, "score" : 209.1, "model-ac" : "2xhfB00" }, { "signature" : { "accession" : "PS51352", "name" : "THIOREDOXIN_2", "description" : "Thioredoxin domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR013766", "name" : "Thioredoxin_domain", "description" : "Thioredoxin domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 1, "end" : 154, "score" : 12.019, "alignment" : "MQVGDQIPCAELyEDTpANKI--NIAEYVK-GKKIVLFAVPgAFTPGCsKTHLPGYVADADKLKSKGISEIiCVSVNDPFVMGaWGKDQNVNGkVKLL---ADPSA---AFtkaleldtdipplggtrskrysmVID-DGKVTQLNVepDGTGLScSLSKSLNV------", "location-fragments" : [ { "start" : 1, "end" : 154, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51352" }, { "signature" : { "accession" : "SSF52833", "name" : "Thioredoxin-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036249", "name" : "Thioredoxin-like_sf", "description" : "Thioredoxin-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 143, "hmmLength" : 162, "location-fragments" : [ { "start" : 2, "end" : 143, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.47E-37, "model-ac" : "0049667" } ], "xref" : [ { "name" : "XP_018910189.1 PREDICTED: peroxiredoxin-5, mitochondrial isoform X2 [Bemisia tabaci]", "id" : "XP_018910189.1" } ] },{ "sequence" : "MADRPKSSDNERGGSEINSNNNSNYENTEDVDPAMNNSASGTHTARNSSHSNSSPHNSGTSSGASSKRKENNPYSFKHFLTGGKQNVGTSHPHHTVSRSNESDENNTMDPSIASSCSRTNRNLILNNPDLASGLPDFVQDHLIMEQCFLESSSNNASNPSFNLENSHIYHIENAILNSSCEESPNTLRSANANDIPFDLTSTMPSEKQEESPIPTPLDLPTYHASNSRPGRPRDPPLDLPSSSMAGPGSANSSEVGASKSLPDFLSDGPIHQRRTDDSADSDRSTLPYSPRESSVEIQVLQTENLRLRREVEWLSSVIKESNDRLERRERRHQVTTNNLEKELDSTRENLRRTMERAIAAEATVCQLQQEVKSSKVHKLQRAEENSSNCSNVGDGNRNVQTPQHDSRQRLGLEIQNITDSAETSIRQLLNNVETLRLIASSLEKATGESSHHGEKVDESKEDPKKT", "md5" : "d3aba6db5aa5ee7ff7d86f73806b6fc5", "matches" : [ { "signature" : { "accession" : "PTHR31259:SF3", "name" : "SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 3 HOMOLOG", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 19, "end" : 465, "hmmStart" : 19, "hmmEnd" : 387, "hmmLength" : 388, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 466, "location-fragments" : [ { "start" : 19, "end" : 465, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-27, "familyName" : "SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 3 HOMOLOG", "score" : 98.3, "model-ac" : "PTHR31259:SF3" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 322, "end" : 360, "location-fragments" : [ { "start" : 322, "end" : 360, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1, "end" : 115, "location-fragments" : [ { "start" : 1, "end" : 115, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 187, "end" : 294, "location-fragments" : [ { "start" : 187, "end" : 294, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 381, "end" : 413, "location-fragments" : [ { "start" : 381, "end" : 413, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 447, "end" : 466, "location-fragments" : [ { "start" : 447, "end" : 466, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 78, "end" : 115, "location-fragments" : [ { "start" : 78, "end" : 115, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 12, "end" : 70, "location-fragments" : [ { "start" : 12, "end" : 70, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 436, "end" : 466, "location-fragments" : [ { "start" : 436, "end" : 466, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR31259", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR026757", "name" : "ENTR1", "description" : "Endosome-associated-trafficking regulator 1", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 19, "end" : 465, "hmmStart" : 19, "hmmEnd" : 387, "hmmLength" : 388, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 1, "envelopeEnd" : 466, "location-fragments" : [ { "start" : 19, "end" : 465, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.2E-27, "familyName" : "SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 3 HOMOLOG", "score" : 98.3, "model-ac" : "PTHR31259" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 244, "end" : 259, "location-fragments" : [ { "start" : 244, "end" : 259, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 383, "end" : 413, "location-fragments" : [ { "start" : 383, "end" : 413, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 187, "end" : 209, "location-fragments" : [ { "start" : 187, "end" : 209, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 425, "end" : 445, "location-fragments" : [ { "start" : 425, "end" : 445, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" } ], "xref" : [ { "name" : "XP_018910066.1 PREDICTED: uncharacterized protein DDB_G0287625 [Bemisia tabaci]", "id" : "XP_018910066.1" } ] },{ "sequence" : "MEATYCMGNDMDVCRMFDQYLYKRNSENIDLSLTVPHNNGFSNMNDQVPPHSQAQNPMTMNPNDPGGYPSSMHLPHSQEHNMGLSSSASYSSPSYTTMTTVSNSHHSHQQQQEQQRREEQQRQQQHQQQQHQQFMQQMQQQQQQQQQQYHYMTMGPASYGSHGRSAQGSSPVVNSVVKNEFGEMQPPCPAEQNTTTSDDSDDSTPHAQMIAGMKRPSPEPVDNGLGKIQKVKPKSQKKKKKRDPNEPTKPVSAYALFFRDTQAAIKGQNPNASFGEVSKIVASMWDSLDAEHKNVYKKKTEAAKKDYLKALAAYRASLVSKGANEADNMYSAGGYGGYGGGYSSYSPPTGLPSPPMSNPMSPHQLPPPGPPGPAAGPPGPPGSMASAKKQPLIMSDNRGNVQTQQGMMGGHMGQQTHLSSQQQQQQVNPSNNYIQQPNQQQVNNCTGPPPSNVVTTTDNNMDPPQPTMTCIRSGCTNPSVVNSEWEDEYCSNECVVTHCRNVFQTWVASNQSNS", "md5" : "2f05b5b22680763e1586fe137206dd1f", "matches" : [ { "signature" : { "accession" : "PF00505", "name" : "HMG_box", "description" : "HMG (high mobility group) box", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR009071", "name" : "HMG_box_dom", "description" : "High mobility group box domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 247, "end" : 315, "hmmStart" : 1, "hmmEnd" : 69, "hmmLength" : 69, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-16, "score" : 60.5, "envelopeStart" : 247, "envelopeEnd" : 315, "postProcessed" : true, "location-fragments" : [ { "start" : 247, "end" : 315, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-16, "score" : 60.5, "model-ac" : "PF00505" }, { "signature" : { "accession" : "PTHR45781", "name" : "FAMILY NOT NAMED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 43, "end" : 513, "hmmStart" : 66, "hmmEnd" : 432, "hmmLength" : 437, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 18, "envelopeEnd" : 514, "location-fragments" : [ { "start" : 43, "end" : 513, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-97, "familyName" : "", "score" : 329.5, "model-ac" : "PTHR45781" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 38, "end" : 251, "location-fragments" : [ { "start" : 38, "end" : 251, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PR00886", "name" : "HIGHMOBLTY12", "description" : "High mobility group (HMG1/HMG2) protein signature", "signatureLibraryRelease" : { "library" : "PRINTS", "version" : "42.0" }, "entry" : null }, "locations" : [ { "start" : 280, "end" : 299, "pvalue" : 9.34E-4, "score" : 29.63, "motifNumber" : 4, "location-fragments" : [ { "start" : 280, "end" : 299, "dc-status" : "CONTINUOUS" } ] }, { "start" : 262, "end" : 280, "pvalue" : 1.54E-5, "score" : 35.48, "motifNumber" : 3, "location-fragments" : [ { "start" : 262, "end" : 280, "dc-status" : "CONTINUOUS" } ] }, { "start" : 299, "end" : 319, "pvalue" : 0.00101, "score" : 37.57, "motifNumber" : 5, "location-fragments" : [ { "start" : 299, "end" : 319, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.0E-5, "graphscan" : "..IiI", "model-ac" : "PR00886" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 110, "end" : 124, "location-fragments" : [ { "start" : 110, "end" : 124, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50118", "name" : "HMG_BOX_2", "description" : "HMG boxes A and B DNA-binding domains profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR009071", "name" : "HMG_box_dom", "description" : "High mobility group box domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 247, "end" : 315, "score" : 15.557, "alignment" : "PTKPVSAYALFFRDTQAAIKGQNPNASFGEVSKIVASMWDSLDAEHKNVYKKKTEAAKKDYLKALAAYR", "location-fragments" : [ { "start" : 247, "end" : 315, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50118" }, { "signature" : { "accession" : "G3DSA:1.10.30.10", "name" : "DNA Binding (I)", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036910", "name" : "HMG_box_dom_sf", "description" : "High mobility group box domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 231, "end" : 330, "hmmStart" : 5, "hmmEnd" : 96, "hmmLength" : 102, "hmmBounds" : "COMPLETE", "evalue" : 4.6E-33, "score" : 115.4, "envelopeStart" : 231, "envelopeEnd" : 330, "postProcessed" : true, "location-fragments" : [ { "start" : 231, "end" : 330, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.6E-33, "score" : 115.4, "model-ac" : "2co9A00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 393, "end" : 460, "location-fragments" : [ { "start" : 393, "end" : 460, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 188, "end" : 204, "location-fragments" : [ { "start" : 188, "end" : 204, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SM00398", "name" : "hmgende2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR009071", "name" : "HMG_box_dom", "description" : "High mobility group box domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 246, "end" : 316, "hmmStart" : 1, "hmmEnd" : 71, "hmmLength" : 71, "hmmBounds" : "COMPLETE", "evalue" : 4.4E-17, "score" : 72.8, "location-fragments" : [ { "start" : 246, "end" : 316, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.4E-17, "score" : 72.8, "model-ac" : "SM00398" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 349, "end" : 460, "location-fragments" : [ { "start" : 349, "end" : 460, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 125, "end" : 176, "location-fragments" : [ { "start" : 125, "end" : 176, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 74, "end" : 109, "location-fragments" : [ { "start" : 74, "end" : 109, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PTHR45781:SF1", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 43, "end" : 513, "hmmStart" : 66, "hmmEnd" : 432, "hmmLength" : 437, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 18, "envelopeEnd" : 514, "location-fragments" : [ { "start" : 43, "end" : 513, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.3E-97, "familyName" : "", "score" : 329.5, "model-ac" : "PTHR45781:SF1" }, { "signature" : { "accession" : "cd00084", "name" : "HMG-box", "description" : "HMG-box", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 247, "end" : 312, "sites" : [ { "description" : "DNA binding site", "numLocations" : 13, "siteLocations" : [ { "start" : 279, "end" : 279, "residue" : "K" }, { "start" : 285, "end" : 285, "residue" : "W" }, { "start" : 255, "end" : 255, "residue" : "A" }, { "start" : 258, "end" : 258, "residue" : "F" }, { "start" : 254, "end" : 254, "residue" : "Y" }, { "start" : 251, "end" : 251, "residue" : "V" }, { "start" : 282, "end" : 282, "residue" : "A" }, { "start" : 266, "end" : 266, "residue" : "K" }, { "start" : 259, "end" : 259, "residue" : "R" }, { "start" : 262, "end" : 262, "residue" : "Q" }, { "start" : 304, "end" : 304, "residue" : "K" }, { "start" : 252, "end" : 252, "residue" : "S" }, { "start" : 249, "end" : 249, "residue" : "K" } ] } ], "evalue" : 1.12411E-20, "score" : 83.8223, "location-fragments" : [ { "start" : 247, "end" : 312, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00084" }, { "signature" : { "accession" : "SSF47095", "name" : "HMG-box", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036910", "name" : "HMG_box_dom_sf", "description" : "High mobility group box domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 233, "end" : 323, "hmmLength" : 108, "location-fragments" : [ { "start" : 233, "end" : 323, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.62E-24, "model-ac" : "0044636" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 108, "end" : 144, "location-fragments" : [ { "start" : 108, "end" : 144, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 349, "end" : 380, "location-fragments" : [ { "start" : 349, "end" : 380, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 38, "end" : 66, "location-fragments" : [ { "start" : 38, "end" : 66, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" } ], "xref" : [ { "name" : "XP_018909784.1 PREDICTED: TOX high mobility group box family member 4-like isoform X2 [Bemisia tabaci]", "id" : "XP_018909784.1" } ] },{ "sequence" : "MYKLKSAQREKVRKFIAFTQTGESTAINCLAQNDWKLELASDNYFQNPEAYYKEPKNSVDRRKLEVLFNKYRDPNETDKMTAEGIMKFLDDLSLSPESKLVLIIAWKFKAAAQCEFSREEFMRGMSELGSDSIDKLKARLPSLDSEIKDQLRFKDFYYFTFNYAKNPGQKCLDLEMAITYWNIVLQGRFKFLDLWCRFLTEHHKRSIPKDTWNLLLDFSLAINDEMSNYDEEGAWPVLIDDFVEWAQPLVSNHSQVHSTQV", "md5" : "13a4f4ab598b62d4e97b8098365a3459", "matches" : [ { "signature" : { "accession" : "G3DSA:1.10.238.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 59, "end" : 148, "hmmStart" : 3, "hmmEnd" : 90, "hmmLength" : 90, "hmmBounds" : "COMPLETE", "evalue" : 5.0E-34, "score" : 118.1, "envelopeStart" : 59, "envelopeEnd" : 148, "postProcessed" : true, "location-fragments" : [ { "start" : 59, "end" : 148, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.0E-34, "score" : 118.9, "model-ac" : "3tduA01" }, { "signature" : { "accession" : "G3DSA:1.10.8.10", "name" : "DNA helicase RuvA subunit", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 2, "end" : 54, "hmmStart" : 6, "hmmEnd" : 51, "hmmLength" : 59, "hmmBounds" : "COMPLETE", "evalue" : 1.5E-10, "score" : 42.5, "envelopeStart" : 2, "envelopeEnd" : 54, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 54, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.6E-11, "score" : 43.9, "model-ac" : "2l4eA00" }, { "signature" : { "accession" : "PTHR12281", "name" : "RP42 RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : { "accession" : "IPR014764", "name" : "DCN-prot", "description" : "Defective-in-cullin neddylation protein", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Neddylation", "databaseName" : "Reactome", "id" : "R-HSA-8951664" } ] } }, "locations" : [ { "start" : 9, "end" : 254, "hmmStart" : 9, "hmmEnd" : 255, "hmmLength" : 259, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 258, "location-fragments" : [ { "start" : 9, "end" : 254, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-116, "familyName" : "DCN1-LIKE PROTEIN 2", "score" : 389.8, "model-ac" : "PTHR12281" }, { "signature" : { "accession" : "PS51229", "name" : "DCUN1", "description" : "DCUN1 domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR005176", "name" : "PONY_dom", "description" : "Potentiating neddylation domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Neddylation", "databaseName" : "Reactome", "id" : "R-HSA-8951664" } ] } }, "locations" : [ { "start" : 59, "end" : 247, "score" : 55.833, "alignment" : "VDRRKLEVLFNKYRDPNETDKMTAEGIMKFLDDLSLSPESKLVLIIAWKFKAAAQCEFSREEFMRGMSELGSDSIDKLKARLPSLDSEIK-DQLRFKDFYYFTFNYAKNPGQKCLDLEMAITYWNIVLQGRF-KFLDLWCRFLTEHHKRSIPKDTWNLLLDFSLAINDEMSNYDEEGAWPVLIDDFVEWAQ", "location-fragments" : [ { "start" : 59, "end" : 247, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51229" }, { "signature" : { "accession" : "PF03556", "name" : "Cullin_binding", "description" : "Cullin binding", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005176", "name" : "PONY_dom", "description" : "Potentiating neddylation domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Neddylation", "databaseName" : "Reactome", "id" : "R-HSA-8951664" } ] } }, "locations" : [ { "start" : 135, "end" : 245, "hmmStart" : 1, "hmmEnd" : 120, "hmmLength" : 120, "hmmBounds" : "COMPLETE", "evalue" : 1.7E-37, "score" : 128.5, "envelopeStart" : 135, "envelopeEnd" : 245, "postProcessed" : true, "location-fragments" : [ { "start" : 135, "end" : 245, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-37, "score" : 128.5, "model-ac" : "PF03556" }, { "signature" : { "accession" : "G3DSA:1.10.238.200", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR042460", "name" : "DCN1-like_PONY", "description" : "DCN1-like, PONY binding domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ { "name" : "Neddylation", "databaseName" : "Reactome", "id" : "R-HSA-8951664" } ] } }, "locations" : [ { "start" : 149, "end" : 257, "hmmStart" : 2, "hmmEnd" : 101, "hmmLength" : 110, "hmmBounds" : "COMPLETE", "evalue" : 3.4E-42, "score" : 145.1, "envelopeStart" : 149, "envelopeEnd" : 257, "postProcessed" : true, "location-fragments" : [ { "start" : 149, "end" : 257, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-42, "score" : 146.2, "model-ac" : "4gaoA02" }, { "signature" : { "accession" : "PF14555", "name" : "UBA_4", "description" : "UBA-like domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 49, "hmmStart" : 1, "hmmEnd" : 41, "hmmLength" : 43, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.9E-8, "score" : 33.4, "envelopeStart" : 9, "envelopeEnd" : 50, "postProcessed" : true, "location-fragments" : [ { "start" : 9, "end" : 49, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.9E-9, "score" : 35.0, "model-ac" : "PF14555" }, { "signature" : { "accession" : "PTHR12281:SF16", "name" : "DCN1-LIKE PROTEIN 2", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 9, "end" : 254, "hmmStart" : 9, "hmmEnd" : 255, "hmmLength" : 259, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 2, "envelopeEnd" : 258, "location-fragments" : [ { "start" : 9, "end" : 254, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-116, "familyName" : "DCN1-LIKE PROTEIN 2", "score" : 389.8, "model-ac" : "PTHR12281:SF16" }, { "signature" : { "accession" : "SSF46934", "name" : "UBA-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR009060", "name" : "UBA-like_sf", "description" : "UBA-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5, "end" : 47, "hmmLength" : 46, "location-fragments" : [ { "start" : 5, "end" : 47, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.67E-8, "model-ac" : "0044670" } ], "xref" : [ { "name" : "XP_018910367.1 PREDICTED: DCN1-like protein 1 [Bemisia tabaci]", "id" : "XP_018910367.1" } ] },{ "sequence" : "MITITPQQFSQPPPFVPNVSVPPPNFHANQPPPQRFHSGHAGQIRHNNYFPQFRPQFRPNNALFDPDFDGKRLRKSTMRKTVDYNAAIIKMLEGRIWQRDYRDRTFLQPDAIYNPELLPPPSYPDNAVNAVTTRFVKTATNKMRCPVFCMAWTPEGRRLVTGTSSGEFTLWNGLTFNFETILQAHDSPVRTMVWSNNDSWMVTADHAGYIKYWQSNMNNIKMFPAHKEAIRGISFSPTDDKFASCSDDGTIRIWDFYQCHEERILRGHGADVKCIDWHPQKGLIISGSKDNQQPIKLWDPKTGQALATLHAHKNTVMDIKWNKNGNWLITASRDHLLKLFDLRNLSTEVQTFRGHKKESSCVSWHPYHEGLFCSGGSDGAILFWHVGADKEVGAIEQAHDSIVWTLAWHPLGHILCSGSNDHTSKFWTRNRPGDQMKDKYNLNTLPQALAGLEDNEIDDVSAIPGMGPEDKVAASPPPAPLNPDTIPGLDVDPAEELKLKAPIKKVPYSKPIPKQFQAQWNVVRGIEDNAEEGQDENAEINPEETPGCLPISEIKPDAIVIYGRLLPVKPGSALQQAIREGKDAIMQLAHSGAIPQLIDVLPIDEETNFDLFAVDDEDEDYYDDNEDWRNWKDDWNEEEPMDEDYRMHNEDYPDEEMHMQGPYPPMQGPPMQGPFPPRPPMFDGNGPGPHGPGGPGPHGPGGPGHHGPGGPGPHGPGGPGPHGQGGPGPHGQGGPGPHGPGGPGPHGPGGPGPHGQGGPGPHGPGGPGPHGPGGPGPHGPGGPGPHGPGGPGLHGPGGPGPRPGFGPPRMMGPRPMGPPGQQFQDMSHGQPRFPPPHFNQGDGEGEYMDGHGPGGPGPHGPGGPGPRGPGGPGPQGQGGPGGPGPRGPGGPGPHGQGGPGPHGPGGPGPRGQGGPGPRGPGFGPPRMMGSRPMGPSGPPFQDRSHGQPRFPPPHFNQGDGEEEYTENNEEEYDENYDNNYDPNQFNDGYHGNDDRSNFRPNGEGWDENYWDENQEEMEDDSYNNYDEGMNRGMPRGRSRGRPPFRGRGRGRGRGRGRGRGGKPDWFDDSNSNYDNNVNNSSNFSRGGGHSRDDDESRFKGHKRFEESEERPRGRGRGRGGPKRARTRGRGW", "md5" : "82bf39a8f4a935e831eff2c4f1378dbd", "matches" : [ { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 962, "end" : 977, "location-fragments" : [ { "start" : 962, "end" : 977, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 396, "end" : 427, "score" : 11.01, "alignment" : "EQAHDSIVWTLAWHPLGHILCSGSNDHTSKFW----------", "location-fragments" : [ { "start" : 396, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1038, "end" : 1056, "location-fragments" : [ { "start" : 1038, "end" : 1056, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 140, "end" : 172, "score" : 8.838, "alignment" : "TNKMRCPVFCMAWTPEGRRLVTGTSSGEFTLWN---------", "location-fragments" : [ { "start" : 140, "end" : 172, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "PTHR22836", "name" : "WD40 REPEAT PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 50, "end" : 965, "hmmStart" : 15, "hmmEnd" : 537, "hmmLength" : 657, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 23, "envelopeEnd" : 1095, "location-fragments" : [ { "start" : 50, "end" : 965, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.6E-247, "familyName" : "WD40 REPEAT PROTEIN", "score" : 825.2, "model-ac" : "PTHR22836" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 641, "end" : 1131, "location-fragments" : [ { "start" : 641, "end" : 1131, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PF00400", "name" : "WD40", "description" : "WD domain, G-beta repeat", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 218, "end" : 255, "hmmStart" : 2, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 5.9E-8, "score" : 33.2, "envelopeStart" : 217, "envelopeEnd" : 255, "postProcessed" : true, "location-fragments" : [ { "start" : 218, "end" : 255, "dc-status" : "CONTINUOUS" } ] }, { "start" : 263, "end" : 291, "hmmStart" : 5, "hmmEnd" : 32, "hmmLength" : 38, "hmmBounds" : "INCOMPLETE", "evalue" : 0.0014, "score" : 19.4, "envelopeStart" : 259, "envelopeEnd" : 299, "postProcessed" : true, "location-fragments" : [ { "start" : 263, "end" : 291, "dc-status" : "CONTINUOUS" } ] }, { "start" : 303, "end" : 341, "hmmStart" : 1, "hmmEnd" : 38, "hmmLength" : 38, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-5, "score" : 26.0, "envelopeStart" : 303, "envelopeEnd" : 341, "postProcessed" : true, "location-fragments" : [ { "start" : 303, "end" : 341, "dc-status" : "CONTINUOUS" } ] }, { "start" : 348, "end" : 384, "hmmStart" : 3, "hmmEnd" : 37, "hmmLength" : 38, "hmmBounds" : "INCOMPLETE", "evalue" : 0.014, "score" : 16.3, "envelopeStart" : 346, "envelopeEnd" : 385, "postProcessed" : true, "location-fragments" : [ { "start" : 348, "end" : 384, "dc-status" : "CONTINUOUS" } ] }, { "start" : 398, "end" : 427, "hmmStart" : 9, "hmmEnd" : 37, "hmmLength" : 38, "hmmBounds" : "INCOMPLETE", "evalue" : 0.0066, "score" : 17.3, "envelopeStart" : 391, "envelopeEnd" : 428, "postProcessed" : true, "location-fragments" : [ { "start" : 398, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-35, "score" : 120.3, "model-ac" : "PF00400" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 663, "end" : 723, "location-fragments" : [ { "start" : 663, "end" : 723, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 352, "end" : 394, "score" : 10.475, "alignment" : "FRGHKKESSCVSWHPYhEGLFCSGGSDGAILFWHVGADKEVGA", "location-fragments" : [ { "start" : 352, "end" : 394, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1008, "end" : 1023, "location-fragments" : [ { "start" : 1008, "end" : 1023, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Negative Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50294", "name" : "WD_REPEATS_REGION", "description" : "Trp-Asp (WD) repeats circular profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR017986", "name" : "WD40_repeat_dom", "description" : "WD40-repeat-containing domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 140, "end" : 437, "score" : 47.615, "alignment" : "TNKMRCPVFCMAWTPEGRRLVTGTSSGEFTLWNGLTFNFETILQAHDSPVRTMVWSNNDSWMVTADHAGYIKYWQ-SNMNNIKMFPAHKEAIRGISFSPTDDKFASCSDDGTIRIWDFYQCHEERILRGHGADVKCIDWHPQKGLIISGSKDNQqpIKLWDPKTGQALATLHAHKNTVMDIKWNKNGNWLITASRDHLLKLFDLRNLSTEVQtFRGHKKESSCVSWHPYhEGLFCSGGSDGAILFWHVGADKEVGAiEQAHDSIVWTLAWHPLGHILCSGSNDHTSKFWTRNRPGDQMK", "location-fragments" : [ { "start" : 140, "end" : 437, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50294" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1068, "end" : 1086, "location-fragments" : [ { "start" : 1068, "end" : 1086, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polar" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF50978", "name" : "WD40 repeat-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036322", "name" : "WD40_repeat_dom_sf", "description" : "WD40-repeat-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 140, "end" : 430, "hmmLength" : 388, "location-fragments" : [ { "start" : 140, "end" : 430, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.58E-77, "model-ac" : "0046612" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 223, "end" : 255, "score" : 14.853, "alignment" : "FPAHKEAIRGISFSPTDDKFASCSDDGTIRIWD---------", "location-fragments" : [ { "start" : 223, "end" : 255, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "SM00320", "name" : "WD40_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 302, "end" : 341, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 9.8E-9, "score" : 45.0, "location-fragments" : [ { "start" : 302, "end" : 341, "dc-status" : "CONTINUOUS" } ] }, { "start" : 216, "end" : 255, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 4.9E-10, "score" : 49.3, "location-fragments" : [ { "start" : 216, "end" : 255, "dc-status" : "CONTINUOUS" } ] }, { "start" : 388, "end" : 428, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 3.7E-5, "score" : 33.1, "location-fragments" : [ { "start" : 388, "end" : 428, "dc-status" : "CONTINUOUS" } ] }, { "start" : 258, "end" : 299, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 1.9E-7, "score" : 40.8, "location-fragments" : [ { "start" : 258, "end" : 299, "dc-status" : "CONTINUOUS" } ] }, { "start" : 175, "end" : 214, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-4, "score" : 31.1, "location-fragments" : [ { "start" : 175, "end" : 214, "dc-status" : "CONTINUOUS" } ] }, { "start" : 132, "end" : 172, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 0.05, "score" : 22.7, "location-fragments" : [ { "start" : 132, "end" : 172, "dc-status" : "CONTINUOUS" } ] }, { "start" : 345, "end" : 385, "hmmStart" : 1, "hmmEnd" : 46, "hmmLength" : 46, "hmmBounds" : "COMPLETE", "evalue" : 3.4E-6, "score" : 36.6, "location-fragments" : [ { "start" : 345, "end" : 385, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.8E-73, "score" : 258.6, "model-ac" : "SM00320" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 641, "end" : 657, "location-fragments" : [ { "start" : 641, "end" : 657, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1087, "end" : 1115, "location-fragments" : [ { "start" : 1087, "end" : 1115, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Polyampholyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 733, "end" : 815, "location-fragments" : [ { "start" : 733, "end" : 815, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "cd00200", "name" : "WD40", "description" : "WD40", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : null }, "locations" : [ { "start" : 144, "end" : 427, "sites" : [ { "description" : "structural tetrad", "numLocations" : 38, "siteLocations" : [ { "start" : 334, "end" : 334, "residue" : "D" }, { "start" : 185, "end" : 185, "residue" : "H" }, { "start" : 225, "end" : 225, "residue" : "A" }, { "start" : 298, "end" : 298, "residue" : "W" }, { "start" : 340, "end" : 340, "residue" : "F" }, { "start" : 399, "end" : 399, "residue" : "H" }, { "start" : 290, "end" : 290, "residue" : "D" }, { "start" : 312, "end" : 312, "residue" : "H" }, { "start" : 248, "end" : 248, "residue" : "D" }, { "start" : 254, "end" : 254, "residue" : "W" }, { "start" : 355, "end" : 355, "residue" : "H" }, { "start" : 184, "end" : 184, "residue" : "A" }, { "start" : 417, "end" : 417, "residue" : "S" }, { "start" : 398, "end" : 398, "residue" : "A" }, { "start" : 213, "end" : 213, "residue" : "W" }, { "start" : 378, "end" : 378, "residue" : "D" }, { "start" : 311, "end" : 311, "residue" : "A" }, { "start" : 384, "end" : 384, "residue" : "W" }, { "start" : 171, "end" : 171, "residue" : "W" }, { "start" : 427, "end" : 427, "residue" : "W" }, { "start" : 172, "end" : 172, "residue" : "N" }, { "start" : 421, "end" : 421, "residue" : "D" }, { "start" : 203, "end" : 203, "residue" : "T" }, { "start" : 161, "end" : 161, "residue" : "T" }, { "start" : 285, "end" : 285, "residue" : "I" }, { "start" : 354, "end" : 354, "residue" : "G" }, { "start" : 207, "end" : 207, "residue" : "A" }, { "start" : 330, "end" : 330, "residue" : "T" }, { "start" : 373, "end" : 373, "residue" : "C" }, { "start" : 268, "end" : 268, "residue" : "H" }, { "start" : 243, "end" : 243, "residue" : "A" }, { "start" : 299, "end" : 299, "residue" : "D" }, { "start" : 385, "end" : 385, "residue" : "H" }, { "start" : 214, "end" : 214, "residue" : "Q" }, { "start" : 226, "end" : 226, "residue" : "H" }, { "start" : 255, "end" : 255, "residue" : "D" }, { "start" : 165, "end" : 165, "residue" : "S" }, { "start" : 341, "end" : 341, "residue" : "D" } ] } ], "evalue" : 9.33384E-72, "score" : 238.774, "location-fragments" : [ { "start" : 144, "end" : 427, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00200" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 309, "end" : 350, "score" : 12.079, "alignment" : "LHAHKNTVMDIKWNKNGNWLITASRDHLLKLFDLRNLSTEVQ", "location-fragments" : [ { "start" : 309, "end" : 350, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 217, "end" : 345, "hmmStart" : 101, "hmmEnd" : 232, "hmmLength" : 451, "hmmBounds" : "INCOMPLETE", "evalue" : 1.7E-37, "score" : 131.1, "envelopeStart" : 212, "envelopeEnd" : 349, "postProcessed" : true, "location-fragments" : [ { "start" : 217, "end" : 345, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.9E-107, "score" : 359.8, "model-ac" : "4j0xA00" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 122, "end" : 216, "hmmStart" : 68, "hmmEnd" : 146, "hmmLength" : 392, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.2E-15, "score" : 57.6, "envelopeStart" : 122, "envelopeEnd" : 221, "postProcessed" : true, "location-fragments" : [ { "start" : 122, "end" : 216, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.9E-63, "score" : 216.4, "model-ac" : "1r5mA00" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 24, "end" : 43, "location-fragments" : [ { "start" : 24, "end" : 43, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:2.130.10.10", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR015943", "name" : "WD40/YVTN_repeat-like_dom_sf", "description" : "WD40/YVTN repeat-like-containing domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 346, "end" : 447, "hmmStart" : 120, "hmmEnd" : 204, "hmmLength" : 352, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 6.0E-19, "score" : 70.2, "envelopeStart" : 342, "envelopeEnd" : 447, "postProcessed" : true, "location-fragments" : [ { "start" : 346, "end" : 447, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-64, "score" : 220.4, "model-ac" : "2aq5A01" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 265, "end" : 291, "score" : 8.737, "alignment" : "LRGHGADVKCIDWHPQKGLIISGSKDN---------------", "location-fragments" : [ { "start" : 265, "end" : 291, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 1116, "end" : 1131, "location-fragments" : [ { "start" : 1116, "end" : 1131, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Positive Polyelectrolyte" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 857, "end" : 922, "location-fragments" : [ { "start" : 857, "end" : 922, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "Proline-rich" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "PS50082", "name" : "WD_REPEATS_2", "description" : "Trp-Asp (WD) repeats profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR001680", "name" : "WD40_repeat", "description" : "WD40 repeat", "type" : "REPEAT", "goXRefs" : [ { "name" : "protein binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005515" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 182, "end" : 214, "score" : 9.64, "alignment" : "LQAHDSPVRTMVWSNNDSWMVTADHAGYIKYWQ---------", "location-fragments" : [ { "start" : 182, "end" : 214, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50082" } ], "xref" : [ { "name" : "XP_018909649.1 PREDICTED: pre-mRNA 3' end processing protein WDR33 [Bemisia tabaci]", "id" : "XP_018909649.1" }, { "name" : "XP_018909648.1 PREDICTED: pre-mRNA 3' end processing protein WDR33 [Bemisia tabaci]", "id" : "XP_018909648.1" } ] },{ "sequence" : "MYTDDYGRNHMLIDVKPEDISQNRENRLSVADVLASLQLQMHLKSTKRHIRARRDTLYPDMLRLLEDPSFSVLDQLSARFECEAAVGKGPLKAFLNSLVLEVKEDTRIFEGASEKTLTYCKQSLKEGLYKKAGQILQLTFLHEGPRPQFLSKALFELISQGSLKNLELRSSLVPDLNTRHAIEQMENAANHHEVNAVIRDNESSYLCAVKKHFLEEKEFFKKEEILKDVLEYHLHDKIKDPLSQFKDGLNEGTSLLKYVEANPAEFWNIFGSVDEVLTAKNFIAAFSSYPVTEDEKRVLAHWKQFVKDCEGESAKVTLTDILEFATGIDNLSALGLSSLNLKVRFSSASQLATSSACSNSVTLPLSLAKQDYEYFCIIMETSIRGSKGFLGRI", "md5" : "e0cdfad950bfb440b909e910c45a3bd8", "matches" : [ { "signature" : { "accession" : "PF00632", "name" : "HECT", "description" : "HECT-domain (ubiquitin-transferase)", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000569", "name" : "HECT_dom", "description" : "HECT domain", "type" : "DOMAIN", "goXRefs" : [ { "name" : "ubiquitin-protein transferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004842" } ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" }, { "name" : "Protein ubiquitination", "databaseName" : "MetaCyc", "id" : "PWY-7511" } ] } }, "locations" : [ { "start" : 128, "end" : 368, "hmmStart" : 36, "hmmEnd" : 283, "hmmLength" : 307, "hmmBounds" : "INCOMPLETE", "evalue" : 5.7E-7, "score" : 29.3, "envelopeStart" : 97, "envelopeEnd" : 390, "postProcessed" : true, "location-fragments" : [ { "start" : 128, "end" : 368, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.1E-7, "score" : 31.7, "model-ac" : "PF00632" }, { "signature" : { "accession" : "PTHR12420:SF37", "name" : "G2/M PHASE-SPECIFIC E3 UBIQUITIN-PROTEIN LIGASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 86, "end" : 344, "hmmStart" : 406, "hmmEnd" : 659, "hmmLength" : 708, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 36, "envelopeEnd" : 387, "location-fragments" : [ { "start" : 86, "end" : 344, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.0E-42, "familyName" : "G2/M PHASE-SPECIFIC E3 UBIQUITIN-PROTEIN LIGASE", "score" : 146.2, "model-ac" : "PTHR12420:SF37" }, { "signature" : { "accession" : "PTHR12420", "name" : "PHD FINGER PROTEIN", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 86, "end" : 344, "hmmStart" : 406, "hmmEnd" : 659, "hmmLength" : 708, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 36, "envelopeEnd" : 387, "location-fragments" : [ { "start" : 86, "end" : 344, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.0E-42, "familyName" : "G2/M PHASE-SPECIFIC E3 UBIQUITIN-PROTEIN LIGASE", "score" : 146.2, "model-ac" : "PTHR12420" }, { "signature" : { "accession" : "SSF56204", "name" : "Hect, E3 ligase catalytic domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035983", "name" : "Hect_E3_ubiquitin_ligase", "description" : "HECT, E3 ligase catalytic domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "ubiquitin-protein transferase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004842" } ], "pathwayXRefs" : [ { "name" : "Antigen processing: Ubiquitination & Proteasome degradation", "databaseName" : "Reactome", "id" : "R-HSA-983168" }, { "name" : "Protein ubiquitination", "databaseName" : "MetaCyc", "id" : "PWY-7511" } ] } }, "locations" : [ { "start" : 38, "end" : 364, "hmmLength" : 374, "location-fragments" : [ { "start" : 38, "end" : 364, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.49E-15, "model-ac" : "0048334" } ], "xref" : [ { "name" : "XP_018910557.1 PREDICTED: G2/M phase-specific E3 ubiquitin-protein ligase-like [Bemisia tabaci]", "id" : "XP_018910557.1" } ] },{ "sequence" : "MEIATAGILIIGDEILNGEVVESNAFYMCCNLRQLGVKVARITVIGDDVEEIASHVMDFSKKFNYVITTGGIGPTHDDVTYQGVAKAFKVPLVCNENLLKYWDKIYSKTGWNLDKSAWKRMATIPGNAKVTFFQSNKNSEGDYTVIVSNIFILPGVPSIVKRVFLPLAKECITSNNVFYSTIIYLNRSEEQVMPYLNPVVEKYDKKVAFGSYPIFSNRIYHAKITVESPVRETFQGAVSDLKSSIPQEWQVNNLEVAAENLQKAINSFLFISQSVEILDECFKRYQLSNIAVAFNGGKDCTALLHLVYAYCRFRSIDVSSKKLQCIYFRSNDVFQELENFVEETVKRYDINLLTIDGEIKTGLDQALKENPQWEAILMGTRQSDPFSSCLQAFQMTDVTWPRVMRVNPMLHWSYEDVWFFLRYLNVPYCSLYDDGYTSLGHGSTTKKNPDLQYLENGVVKYYPAFKLKYGDSERNGRK", "md5" : "77650acf16a04c16469b665b32f58d65", "matches" : [ { "signature" : { "accession" : "G3DSA:3.40.980.10", "name" : "Molybdenum cofactor biosynthesis proteins", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR036425", "name" : "MoaB/Mog-like_dom_sf", "description" : "MoaB/Mog-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 2, "end" : 175, "hmmStart" : 5, "hmmEnd" : 165, "hmmLength" : 172, "hmmBounds" : "COMPLETE", "evalue" : 8.4E-48, "score" : 164.2, "envelopeStart" : 2, "envelopeEnd" : 175, "postProcessed" : true, "location-fragments" : [ { "start" : 2, "end" : 175, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.9E-48, "score" : 165.3, "model-ac" : "3kbqB00" }, { "signature" : { "accession" : "SSF53218", "name" : "Molybdenum cofactor biosynthesis proteins", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036425", "name" : "MoaB/Mog-like_dom_sf", "description" : "MoaB/Mog-like domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 4, "end" : 204, "hmmLength" : 190, "location-fragments" : [ { "start" : 4, "end" : 204, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.96E-32, "model-ac" : "0036437" }, { "signature" : { "accession" : "G3DSA:3.40.50.620", "name" : "HUPs", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR014729", "name" : "Rossmann-like_a/b/a_fold", "description" : "Rossmann-like alpha/beta/alpha sandwich fold", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 249, "end" : 478, "hmmStart" : 34, "hmmEnd" : 303, "hmmLength" : 306, "hmmBounds" : "COMPLETE", "evalue" : 9.0E-75, "score" : 253.6, "envelopeStart" : 249, "envelopeEnd" : 478, "postProcessed" : true, "location-fragments" : [ { "start" : 249, "end" : 478, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.6E-75, "score" : 254.1, "model-ac" : "2wsiA00" }, { "signature" : { "accession" : "SM00852", "name" : "MoCF_biosynth_3a", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR001453", "name" : "MoaB/Mog_dom", "description" : "MoaB/Mog domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 174, "hmmStart" : 1, "hmmEnd" : 201, "hmmLength" : 201, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-27, "score" : 107.9, "location-fragments" : [ { "start" : 7, "end" : 174, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-27, "score" : 107.9, "model-ac" : "SM00852" }, { "signature" : { "accession" : "PF01507", "name" : "PAPS_reduct", "description" : "Phosphoadenosine phosphosulfate reductase family", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002500", "name" : "PAPS_reduct", "description" : "Phosphoadenosine phosphosulphate reductase", "type" : "DOMAIN", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ { "name" : "Vitamin B2 (riboflavin) metabolism", "databaseName" : "Reactome", "id" : "R-HSA-196843" } ] } }, "locations" : [ { "start" : 289, "end" : 355, "hmmStart" : 1, "hmmEnd" : 58, "hmmLength" : 174, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.7E-7, "score" : 30.8, "envelopeStart" : 289, "envelopeEnd" : 362, "postProcessed" : true, "location-fragments" : [ { "start" : 289, "end" : 355, "dc-status" : "CONTINUOUS" } ] }, { "start" : 363, "end" : 445, "hmmStart" : 91, "hmmEnd" : 172, "hmmLength" : 174, "hmmBounds" : "INCOMPLETE", "evalue" : 6.2E-19, "score" : 68.7, "envelopeStart" : 359, "envelopeEnd" : 447, "postProcessed" : true, "location-fragments" : [ { "start" : 363, "end" : 445, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.3E-29, "score" : 101.8, "model-ac" : "PF01507" }, { "signature" : { "accession" : "PF00994", "name" : "MoCF_biosynth", "description" : "Probable molybdopterin binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR001453", "name" : "MoaB/Mog_dom", "description" : "MoaB/Mog domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 7, "end" : 165, "hmmStart" : 1, "hmmEnd" : 135, "hmmLength" : 144, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 3.5E-29, "score" : 101.3, "envelopeStart" : 7, "envelopeEnd" : 173, "postProcessed" : true, "location-fragments" : [ { "start" : 7, "end" : 165, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-29, "score" : 102.3, "model-ac" : "PF00994" }, { "signature" : { "accession" : "PTHR23293", "name" : "FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 66, "end" : 478, "hmmStart" : 2, "hmmEnd" : 248, "hmmLength" : 251, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 65, "envelopeEnd" : 478, "location-fragments" : [ { "start" : 66, "end" : 478, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-82, "familyName" : "FAD SYNTHASE", "score" : 276.8, "model-ac" : "PTHR23293" }, { "signature" : { "accession" : "cd01713", "name" : "PAPS_reductase", "description" : "PAPS_reductase", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR002500", "name" : "PAPS_reduct", "description" : "Phosphoadenosine phosphosulphate reductase", "type" : "DOMAIN", "goXRefs" : [ { "name" : "catalytic activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0003824" } ], "pathwayXRefs" : [ { "name" : "Vitamin B2 (riboflavin) metabolism", "databaseName" : "Reactome", "id" : "R-HSA-196843" } ] } }, "locations" : [ { "start" : 289, "end" : 440, "sites" : [ { "description" : "Active Sites", "numLocations" : 4, "siteLocations" : [ { "start" : 368, "end" : 368, "residue" : "K" }, { "start" : 388, "end" : 388, "residue" : "S" }, { "start" : 401, "end" : 401, "residue" : "P" }, { "start" : 405, "end" : 405, "residue" : "R" } ] } ], "evalue" : 1.21785E-40, "score" : 141.773, "location-fragments" : [ { "start" : 289, "end" : 440, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd01713" }, { "signature" : { "accession" : "SSF52402", "name" : "Adenine nucleotide alpha hydrolases-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : null }, "locations" : [ { "start" : 265, "end" : 435, "hmmLength" : 211, "location-fragments" : [ { "start" : 265, "end" : 435, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.75E-36, "model-ac" : "0051645" }, { "signature" : { "accession" : "cd00885", "name" : "cinA", "description" : "cinA", "signatureLibraryRelease" : { "library" : "CDD", "version" : "3.17" }, "entry" : { "accession" : "IPR001453", "name" : "MoaB/Mog_dom", "description" : "MoaB/Mog domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 5, "end" : 164, "sites" : [ { "description" : "putative MPT binding site", "numLocations" : 7, "siteLocations" : [ { "start" : 159, "end" : 159, "residue" : "I" }, { "start" : 73, "end" : 73, "residue" : "G" }, { "start" : 71, "end" : 71, "residue" : "G" }, { "start" : 72, "end" : 72, "residue" : "I" }, { "start" : 162, "end" : 162, "residue" : "R" }, { "start" : 154, "end" : 154, "residue" : "P" }, { "start" : 155, "end" : 155, "residue" : "G" } ] } ], "evalue" : 8.32068E-51, "score" : 168.431, "location-fragments" : [ { "start" : 5, "end" : 164, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "cd00885" }, { "signature" : { "accession" : "PTHR23293:SF9", "name" : "FAD SYNTHASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 66, "end" : 478, "hmmStart" : 2, "hmmEnd" : 248, "hmmLength" : 251, "hmmBounds" : "C_TERMINAL_COMPLETE", "envelopeStart" : 65, "envelopeEnd" : 478, "location-fragments" : [ { "start" : 66, "end" : 478, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.3E-82, "familyName" : "FAD SYNTHASE", "score" : 276.8, "model-ac" : "PTHR23293:SF9" } ], "xref" : [ { "name" : "XP_018909652.1 PREDICTED: FAD synthase-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909652.1" } ] },{ "sequence" : "MYLLTCPNYYKSGRRAAGHFTSVSTCVRGPPLGRATAPVSQPPSRYIYLLHSTMPAIINNKGPYIAVIEEGTRTVKFVLFSAETQEEVVSYSVDVPGESPQEGWAEQDPNTLLSAVHLCIEETMPQLATIGASSKDIVALGITNQRETTIVWDSITGEPLYNAILWSDMRADVTVDEVLAKFPDNNKDYLKPLSGLPVSPYFSALKLKWLIDNVPSVRKAIREHRCLFGTVDSWLIWNLTGGKDGGLHITDVTNASRTMLMNIDSLQWDPLLCKHFHIPMEILPEIRSSSEIYGLVKGHMLDGVPISGILGNQQAALVGQRCFKEGQAKNTYRSGCFLLYNTGNNRVHSSQGLVTTVAFQHGRDKRPVYALEGSVAVAGTALKWLRDNLNMMKDNEEAEDLAEAVKTTGDVYFVPAFAGLYAPYWRKDARGILCGLTQFTTKGHIIRAALEAVCYQTRDILEAMHRDCGFPLSTLHVDGQMTTNRLLMQLQADISGIPVQRNNKKDITALGVAYMAASAAGIDVWDLENLSANSGSDASLEDTFLPSISHEERNLRYTKWKMAVHRSLGWAMPKKSDVMTGNDSDSHTNVCKSSALAEKYCVNSDNVRSSEINLFNKPPSYGNEENCLTANHEFSVKKINNYDKENYSNVPFKMADKPSFGEKHSHAKDISNIEILPANRVFSQNFEPDENQNTLKETSLDSNILRETCLDQNILIGNSVSNNLLIEVVDKKDINENGITEELFEDIFENKENLLTDILEKAKITNFEGSLAQVDSNLEKPHIFPAKYILAAHIKSCHNDDIFVLGHHSR", "md5" : "dec0f96f625d849ba115283de82c3e49", "matches" : [ { "signature" : { "accession" : "PF00370", "name" : "FGGY_N", "description" : "FGGY family of carbohydrate kinases, N-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018484", "name" : "Carb_kinase_FGGY_N", "description" : "Carbohydrate kinase, FGGY, N-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 64, "end" : 319, "hmmStart" : 1, "hmmEnd" : 245, "hmmLength" : 245, "hmmBounds" : "COMPLETE", "evalue" : 2.7E-66, "score" : 223.6, "envelopeStart" : 64, "envelopeEnd" : 319, "postProcessed" : true, "location-fragments" : [ { "start" : 64, "end" : 319, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-66, "score" : 224.5, "model-ac" : "PF00370" }, { "signature" : { "accession" : "PF02782", "name" : "FGGY_C", "description" : "FGGY family of carbohydrate kinases, C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR018485", "name" : "Carb_kinase_FGGY_C", "description" : "Carbohydrate kinase, FGGY, C-terminal", "type" : "DOMAIN", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 328, "end" : 519, "hmmStart" : 1, "hmmEnd" : 197, "hmmLength" : 198, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.2E-60, "score" : 204.6, "envelopeStart" : 328, "envelopeEnd" : 520, "postProcessed" : true, "location-fragments" : [ { "start" : 328, "end" : 519, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.5E-61, "score" : 205.6, "model-ac" : "PF02782" }, { "signature" : { "accession" : "PS00933", "name" : "FGGY_KINASES_1", "description" : "FGGY family of carbohydrate kinases signature 1.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018483", "name" : "Carb_kinase_FGGY_CS", "description" : "Carbohydrate kinase, FGGY, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Glycerol degradation I", "databaseName" : "MetaCyc", "id" : "PWY-4261" }, { "name" : "Glycerolipid metabolism", "databaseName" : "KEGG", "id" : "00561+2.7.1.30" } ] } }, "locations" : [ { "start" : 201, "end" : 213, "level" : "STRONG", "cigarAlignment" : "1M1I1M2I8M", "alignment" : "YfSalKLKWLIDN", "location-fragments" : [ { "start" : 201, "end" : 213, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00933" }, { "signature" : { "accession" : "G3DSA:3.30.420.40", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 58, "end" : 320, "hmmStart" : 9, "hmmEnd" : 267, "hmmLength" : 268, "hmmBounds" : "COMPLETE", "evalue" : 1.1E-90, "score" : 305.5, "envelopeStart" : 58, "envelopeEnd" : 320, "postProcessed" : true, "location-fragments" : [ { "start" : 58, "end" : 320, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.5E-91, "score" : 308.4, "model-ac" : "3wxlA01" }, { "signature" : { "accession" : "PTHR10196:SF40", "name" : "FI03690P", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 63, "end" : 585, "hmmStart" : 8, "hmmEnd" : 530, "hmmLength" : 558, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 52, "envelopeEnd" : 610, "location-fragments" : [ { "start" : 63, "end" : 585, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-255, "familyName" : "FI03690P", "score" : 850.7, "model-ac" : "PTHR10196:SF40" }, { "signature" : { "accession" : "SSF53067", "name" : "Actin-like ATPase domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR043129", "name" : "ATPase_NBD", "description" : "ATPase, nucleotide binding domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 64, "end" : 322, "hmmLength" : 252, "location-fragments" : [ { "start" : 64, "end" : 322, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.04E-70, "model-ac" : "0049108" }, { "signature" : { "accession" : "G3DSA:3.30.420.40", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 321, "end" : 572, "hmmStart" : 2, "hmmEnd" : 244, "hmmLength" : 247, "hmmBounds" : "COMPLETE", "evalue" : 2.2E-81, "score" : 274.6, "envelopeStart" : 321, "envelopeEnd" : 572, "postProcessed" : true, "location-fragments" : [ { "start" : 321, "end" : 572, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.3E-81, "score" : 275.3, "model-ac" : "3ezwD02" }, { "signature" : { "accession" : "SSF53067", "name" : "Actin-like ATPase domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR043129", "name" : "ATPase_NBD", "description" : "ATPase, nucleotide binding domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 322, "end" : 571, "hmmLength" : 246, "location-fragments" : [ { "start" : 322, "end" : 571, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.75E-69, "model-ac" : "0035709" }, { "signature" : { "accession" : "TIGR01311", "name" : "TIGR01311", "description" : "glycerol_kin: glycerol kinase", "signatureLibraryRelease" : { "library" : "TIGRFAM", "version" : "15.0" }, "entry" : { "accession" : "IPR005999", "name" : "Glycerol_kin", "description" : "Glycerol kinase", "type" : "FAMILY", "goXRefs" : [ { "name" : "glycerol-3-phosphate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0006072" }, { "name" : "glycerol kinase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0004370" } ], "pathwayXRefs" : [ { "name" : "Glycerol degradation I", "databaseName" : "MetaCyc", "id" : "PWY-4261" }, { "name" : "Triglyceride biosynthesis", "databaseName" : "Reactome", "id" : "R-HSA-75109" }, { "name" : "Glycerolipid metabolism", "databaseName" : "KEGG", "id" : "00561+2.7.1.30" } ] } }, "locations" : [ { "start" : 63, "end" : 570, "hmmStart" : 1, "hmmEnd" : 496, "hmmLength" : 496, "hmmBounds" : "COMPLETE", "evalue" : 2.9E-199, "score" : 660.4, "envelopeStart" : 63, "envelopeEnd" : 570, "postProcessed" : false, "location-fragments" : [ { "start" : 63, "end" : 570, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.3E-199, "score" : 660.7, "model-ac" : "TIGR01311" }, { "signature" : { "accession" : "PS00445", "name" : "FGGY_KINASES_2", "description" : "FGGY family of carbohydrate kinases signature 2.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR018483", "name" : "Carb_kinase_FGGY_CS", "description" : "Carbohydrate kinase, FGGY, conserved site", "type" : "CONSERVED_SITE", "goXRefs" : [ { "name" : "phosphotransferase activity, alcohol group as acceptor", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016773" }, { "name" : "carbohydrate metabolic process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0005975" } ], "pathwayXRefs" : [ { "name" : "Glycerol degradation I", "databaseName" : "MetaCyc", "id" : "PWY-4261" }, { "name" : "Glycerolipid metabolism", "databaseName" : "KEGG", "id" : "00561+2.7.1.30" } ] } }, "locations" : [ { "start" : 431, "end" : 451, "level" : "STRONG", "cigarAlignment" : "1M1I4M7I8M", "alignment" : "GiLCGLtqfttkgHIIRAALE", "location-fragments" : [ { "start" : 431, "end" : 451, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00445" }, { "signature" : { "accession" : "PTHR10196", "name" : "SUGAR KINASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 63, "end" : 585, "hmmStart" : 8, "hmmEnd" : 530, "hmmLength" : 558, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 52, "envelopeEnd" : 610, "location-fragments" : [ { "start" : 63, "end" : 585, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.8E-255, "familyName" : "FI03690P", "score" : 850.7, "model-ac" : "PTHR10196" } ], "xref" : [ { "name" : "XP_018909612.1 PREDICTED: glycerol kinase-like isoform X1 [Bemisia tabaci]", "id" : "XP_018909612.1" } ] },{ "sequence" : "MNVIRSDLNVPTMQSEVALTINGTSYKVSSSLSVDTSLNEFIRTIAHLKGTKFMCLEGGCGACIVTAKRKDATTGKEYIFAVNSCLTPIFACHGWSVTTIEGIGSKATGYNEIQSRLASFNGSQCGFCSPGMVMNMYSLVKGNEDVFMKTVENSFGGNICRCTGYRPILDAFKSLCTDAPKVYHPDLCSDIEDFPRLCLKTEEICSQACSNKNRCLPEESIEDDFDLLYVENLSLMLSNDVKWYKVDDKKQIFEIFDMIDDFQSYQLVAGNTARGAYRTGDFDYYIDINSVAELSDWILQDNALILGSNITLTKTMNIFERISQKYPRFSYLKVFADHIDLVANVPIRNVGTLAGNLSLKNQHPEFPSDIYLLFVLVRALYVEETSMGTSDTKFVEELIATSLRKKLITCFILPALDDSYIIKTYKIMPCAQNAKAIVNAGFKIKLSNKDALTVSEATIVFGGITPNYVHAEQTQNYLVGKSLSDSQAVQGALDKLDYELHPNFSPPDASPIYRKRLAQSLFYKFILSLKPGSIQEKYRSGGETLQRPRSSGKQSFTSDRKLWPVNKAIPKLEAYSQCSGEAEYTNDIPSLPGELFGALVLAPAGPGTLDSIDTSVAMRLNGVKSFFSAKNIPGINIFTPPGEIFSPDTEPVFADKYVTFSGQPVGIMVAETQLLANKAAGMVRVNVTNLKKPLLTPEEVLDSGDQSRVRFTQSIERKAKKGSGKHIIKGSFECREQYHFHMETQTCLAVPTDEGIDLYPSSQYLSTTQRAISLALKLPENCINVQNRRVGGGYGGKLSRMPQIAIPCALGAFILRKPVRIVLSIESNMQAIGKRTCCLSTYEVSVDDEGKVQYLDMNIHQDLGSSFNDNTIPLTLQNVVNCYDSSTWKVDAYAVRTDKSSNTYCRAPGACEGIATIEHVFEHIATELKKDPLVVRATNFADDSKEHLGTIIDQLKESSDFDNRKKKIQKFNGENRWRKQGISITPMRFALGLFGNFHVLVSIYQSDGSVSITHGGIEMGQGINTKAAQVCAYKFEIDVEMVKIKPSNVLTAPNDFGSVNSMTSDSVCQGVIICCDILLERLSPIKAKLSPDAKWQEVIAAAAVENIDLCAIHMYTIKDIGEKNDMRYNTKTYNIFGACVTEVEVDILTGKYLILRTDIIEDAGVSLNPELDVGQVEGAFVLGLGYWLTEDIIFDCNTGKVLTDRTWNYKPPGFKDIPCDFRVTILKNYSDPNGSPFFLRSKATGEPPLCMSCGVMFALRQAINASRCDAGKPDDWCDISVPFSPEKVFLAAFTGTQEYKLG", "md5" : "b9bbdae53162edad919aefd633ce7d32", "matches" : [ { "signature" : { "accession" : "SSF56176", "name" : "FAD-binding/transporter-associated domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036318", "name" : "FAD-bd_PCMH-like_sf", "description" : "FAD-binding, type PCMH-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "flavin adenine dinucleotide binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0050660" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 236, "end" : 414, "hmmLength" : 216, "location-fragments" : [ { "start" : 236, "end" : 414, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.02E-21, "model-ac" : "0049208" }, { "signature" : { "accession" : "PF00941", "name" : "FAD_binding_5", "description" : "FAD binding domain in molybdopterin dehydrogenase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002346", "name" : "Mopterin_DH_FAD-bd", "description" : "Molybdopterin dehydrogenase, FAD-binding", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 241, "end" : 390, "hmmStart" : 3, "hmmEnd" : 141, "hmmLength" : 171, "hmmBounds" : "INCOMPLETE", "evalue" : 4.1E-16, "score" : 59.2, "envelopeStart" : 239, "envelopeEnd" : 416, "postProcessed" : true, "location-fragments" : [ { "start" : 241, "end" : 390, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.7E-16, "score" : 60.5, "model-ac" : "PF00941" }, { "signature" : { "accession" : "PS00197", "name" : "2FE2S_FER_1", "description" : "2Fe-2S ferredoxin-type iron-sulfur binding region signature.", "signatureLibraryRelease" : { "library" : "PROSITE_PATTERNS", "version" : "2019_11" }, "entry" : { "accession" : "IPR006058", "name" : "2Fe2S_fd_BS", "description" : "2Fe-2S ferredoxin, iron-sulphur binding site", "type" : "BINDING_SITE", "goXRefs" : [ { "name" : "2 iron, 2 sulfur cluster binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0051537" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 55, "end" : 63, "level" : "STRONG", "cigarAlignment" : "9M", "alignment" : "CLEGGCGAC", "location-fragments" : [ { "start" : 55, "end" : 63, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS00197" }, { "signature" : { "accession" : "SSF47741", "name" : "CO dehydrogenase ISP C-domain like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036884", "name" : "2Fe-2S-bd_dom_sf", "description" : "[2Fe-2S]-binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 111, "end" : 180, "hmmLength" : 113, "location-fragments" : [ { "start" : 111, "end" : 180, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.75E-27, "model-ac" : "0044863" }, { "signature" : { "accession" : "SM01092", "name" : "CO_deh_flav_C_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR005107", "name" : "CO_DH_flav_C", "description" : "CO dehydrogenase flavoprotein, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 423, "end" : 529, "hmmStart" : 1, "hmmEnd" : 118, "hmmLength" : 118, "hmmBounds" : "COMPLETE", "evalue" : 8.2E-15, "score" : 65.2, "location-fragments" : [ { "start" : 423, "end" : 529, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 8.2E-15, "score" : 65.2, "model-ac" : "SM01092" }, { "signature" : { "accession" : "PS51387", "name" : "FAD_PCMH", "description" : "PCMH-type FAD-binding domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR016166", "name" : "FAD-bd_PCMH", "description" : "FAD-binding domain, PCMH-type", "type" : "DOMAIN", "goXRefs" : [ { "name" : "FAD binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0071949" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 236, "end" : 418, "score" : 14.794, "alignment" : "MLSNDVKWYKVDDKKQIFEIFDMI-DDFQSYQLVAGNTARGAYRTGD--FDYYIDINSVAELSDWILQDNALILGSNITLTKTMNIferisqkyPRFSYLKVFADHIDLVANVPIRNVGTLAGNLSlknQHPEFPSDIYLLFVLVRALYVEEtSMGTSDTKFVEE---L--IATSLRKKLITCFILPALDD", "location-fragments" : [ { "start" : 236, "end" : 418, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS51387" }, { "signature" : { "accession" : "PF01315", "name" : "Ald_Xan_dh_C", "description" : "Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000674", "name" : "Ald_Oxase/Xan_DH_a/b", "description" : "Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 579, "end" : 687, "hmmStart" : 1, "hmmEnd" : 106, "hmmLength" : 110, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 4.5E-21, "score" : 75.3, "envelopeStart" : 579, "envelopeEnd" : 691, "postProcessed" : true, "location-fragments" : [ { "start" : 579, "end" : 687, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-21, "score" : 76.3, "model-ac" : "PF01315" }, { "signature" : { "accession" : "SSF54665", "name" : "CO dehydrogenase molybdoprotein N-domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036856", "name" : "Ald_Oxase/Xan_DH_a/b_sf", "description" : "Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 538, "end" : 687, "hmmLength" : 158, "location-fragments" : [ { "start" : 538, "end" : 687, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.32E-33, "model-ac" : "0046832" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 538, "end" : 557, "location-fragments" : [ { "start" : 538, "end" : 557, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "SSF55447", "name" : "CO dehydrogenase flavoprotein C-terminal domain-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036683", "name" : "CO_DH_flav_C_dom_sf", "description" : "CO dehydrogenase flavoprotein, C-terminal domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 421, "end" : 530, "hmmLength" : 117, "location-fragments" : [ { "start" : 421, "end" : 530, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.45E-24, "model-ac" : "0037701" }, { "signature" : { "accession" : "SM01008", "name" : "Ald_Xan_dh_C_2", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000674", "name" : "Ald_Oxase/Xan_DH_a/b", "description" : "Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 579, "end" : 691, "hmmStart" : 1, "hmmEnd" : 136, "hmmLength" : 136, "hmmBounds" : "COMPLETE", "evalue" : 7.3E-30, "score" : 115.2, "location-fragments" : [ { "start" : 579, "end" : 691, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 7.3E-30, "score" : 115.2, "model-ac" : "SM01008" }, { "signature" : { "accession" : "PF03450", "name" : "CO_deh_flav_C", "description" : "CO dehydrogenase flavoprotein C-terminal domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR005107", "name" : "CO_DH_flav_C", "description" : "CO dehydrogenase flavoprotein, C-terminal", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 423, "end" : 528, "hmmStart" : 1, "hmmEnd" : 102, "hmmLength" : 103, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 2.7E-25, "score" : 88.5, "envelopeStart" : 423, "envelopeEnd" : 529, "postProcessed" : true, "location-fragments" : [ { "start" : 423, "end" : 528, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.4E-25, "score" : 89.4, "model-ac" : "PF03450" }, { "signature" : { "accession" : "G3DSA:3.30.365.10", "name" : "Aldehyde Oxidoreductase; domain 4", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 13, "end" : 1300, "hmmStart" : 4, "hmmEnd" : 1310, "hmmLength" : 1333, "hmmBounds" : "COMPLETE", "evalue" : 0.0, "score" : 1213.1, "envelopeStart" : 13, "envelopeEnd" : 1300, "postProcessed" : true, "location-fragments" : [ { "start" : 13, "end" : 1300, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "score" : 1213.5, "model-ac" : "2ckjB00" }, { "signature" : { "accession" : "PIRSF000127", "name" : "Xanthine_dh", "description" : null, "signatureLibraryRelease" : { "library" : "PIRSF", "version" : "3.10" }, "entry" : { "accession" : "IPR016208", "name" : "Ald_Oxase/xanthine_DH", "description" : "Aldehyde oxidase/xanthine dehydrogenase", "type" : "FAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" }, { "name" : "iron ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0005506" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 9, "end" : 1301, "hmmStart" : 13, "hmmEnd" : 1294, "hmmLength" : 1331, "hmmBounds" : "INCOMPLETE", "evalue" : 0.0, "score" : 1264.1, "envelopeStart" : 9, "envelopeEnd" : 1301, "postProcessed" : false, "location-fragments" : [ { "start" : 9, "end" : 1301, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "score" : 1264.3, "model-ac" : "PIRSF000127" }, { "signature" : { "accession" : "PTHR11908", "name" : "XANTHINE DEHYDROGENASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 1292, "hmmStart" : 2, "hmmEnd" : 1172, "hmmLength" : 1181, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 14, "envelopeEnd" : 1300, "location-fragments" : [ { "start" : 15, "end" : 1292, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "ALDEHYDE OXIDASE 1-RELATED", "score" : 1412.2, "model-ac" : "PTHR11908" }, { "signature" : { "accession" : "SSF56003", "name" : "Molybdenum cofactor-binding domain", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR037165", "name" : "AldOxase/xan_DH_Mopterin-bd_sf", "description" : "Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 722, "end" : 1291, "hmmLength" : 654, "location-fragments" : [ { "start" : 722, "end" : 1291, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.01E-139, "model-ac" : "0039729" }, { "signature" : { "accession" : "PF02738", "name" : "Ald_Xan_dh_C2", "description" : "Molybdopterin-binding domain of aldehyde dehydrogenase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR008274", "name" : "AldOxase/xan_DH_Mopterin-bd", "description" : "Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 725, "end" : 1218, "hmmStart" : 26, "hmmEnd" : 552, "hmmLength" : 552, "hmmBounds" : "C_TERMINAL_COMPLETE", "evalue" : 2.2E-129, "score" : 432.5, "envelopeStart" : 705, "envelopeEnd" : 1218, "postProcessed" : true, "location-fragments" : [ { "start" : 725, "end" : 1218, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-129, "score" : 432.9, "model-ac" : "PF02738" }, { "signature" : { "accession" : "PF01799", "name" : "Fer2_2", "description" : "[2Fe-2S] binding domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR002888", "name" : "2Fe-2S-bd", "description" : "[2Fe-2S]-binding", "type" : "DOMAIN", "goXRefs" : [ { "name" : "oxidation-reduction process", "databaseName" : "GO", "category" : "BIOLOGICAL_PROCESS", "id" : "GO:0055114" }, { "name" : "oxidoreductase activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0016491" }, { "name" : "metal ion binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0046872" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 99, "end" : 172, "hmmStart" : 1, "hmmEnd" : 75, "hmmLength" : 76, "hmmBounds" : "N_TERMINAL_COMPLETE", "evalue" : 1.3E-22, "score" : 79.6, "envelopeStart" : 99, "envelopeEnd" : 173, "postProcessed" : true, "location-fragments" : [ { "start" : 99, "end" : 172, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.9E-23, "score" : 80.7, "model-ac" : "PF01799" }, { "signature" : { "accession" : "PTHR11908:SF132", "name" : "ALDEHYDE OXIDASE 1-RELATED", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 15, "end" : 1292, "hmmStart" : 2, "hmmEnd" : 1172, "hmmLength" : 1181, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 14, "envelopeEnd" : 1300, "location-fragments" : [ { "start" : 15, "end" : 1292, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 0.0, "familyName" : "ALDEHYDE OXIDASE 1-RELATED", "score" : 1412.2, "model-ac" : "PTHR11908:SF132" }, { "signature" : { "accession" : "SSF54292", "name" : "2Fe-2S ferredoxin-like", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR036010", "name" : "2Fe-2S_ferredoxin-like_sf", "description" : "2Fe-2S ferredoxin-like superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ { "name" : "electron transfer activity", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0009055" }, { "name" : "iron-sulfur cluster binding", "databaseName" : "GO", "category" : "MOLECULAR_FUNCTION", "id" : "GO:0051536" } ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 16, "end" : 103, "hmmLength" : 90, "location-fragments" : [ { "start" : 16, "end" : 103, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.94E-16, "model-ac" : "0037699" } ], "xref" : [ { "name" : "XP_018909623.1 PREDICTED: xanthine dehydrogenase-like [Bemisia tabaci]", "id" : "XP_018909623.1" } ] },{ "sequence" : "MKPGPVDLLIGADLYPHIYDGRKIILDENWPIALSSIYGWVMTGKFSAPHDATRIAAVTTSESAPITALLSINSESIETCLRRHWEIEEPPSRPLKSPNDLLAEELFTEKHSIDSDGRYSVPMLLTEKKMNLGDSYHLAKNRLIKLEHRLNGNPDFRNAYKDFMKEYEELGHMKQVDNDSIGQGKYYIPHHWIWKQTSTSSKMRVVFDASMKTTSGKALNDVVLKGEKLQTDIIQVLTLFRFPRYVFTADVCKMYRQILVNQEDRPYQRILWREDPSQPIKEYELQTVTYGVTSSPYVCLRTMRQHGENTGEKYPVAKEIPTKKVFVDDILAGADSIQETKHARDEIIECAGECNMEVKKWSSNDPEILEDLPESNLKTPVEFSDADSSESLLGLQWQPNSNIFSFKVEKITPVYTKRGIASVVAQIFDPLGLISPIMLKGKQFLQQLWLLGIDWDEAVPLELQAQWKKYTEELIKISEIRIPRHVSLIDEVKFDLVGFSDASKLGYSGNVYLRVESSSGEVKTSLLMAKTKVAPLKPVSVPRLELQGAALLPELLDAAHYICSMAHPIRKVFAYSDSTVVLSWLQTPPYRLKVFVANRVTRILEVLTPQHWGHVKSEDNPSDLASRGCMPDRLADNSLWWHGPKWLQEPEEKWPKLSPFDPESKAEIIDKLPDIVTLVQNKQESWEETFLKSFSEFVPLLRTTAWMLRFSHNARHPTKKRTMDRFPARSSKRPGTGG", "md5" : "ede0488682094febe997db9dea4ed119", "matches" : [ { "signature" : { "accession" : "PTHR22955", "name" : "RETROTRANSPOSON", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 84, "end" : 718, "hmmStart" : 548, "hmmEnd" : 1129, "hmmLength" : 1456, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 53, "envelopeEnd" : 727, "location-fragments" : [ { "start" : 84, "end" : 718, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-151, "familyName" : "", "score" : 507.5, "model-ac" : "PTHR22955" }, { "signature" : { "accession" : "G3DSA:3.10.10.10", "name" : "HIV Type 1 Reverse Transcriptase", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 157, "end" : 292, "hmmStart" : 25, "hmmEnd" : 199, "hmmLength" : 217, "hmmBounds" : "INCOMPLETE", "evalue" : 6.6E-10, "score" : 40.7, "envelopeStart" : 139, "envelopeEnd" : 363, "postProcessed" : true, "location-fragments" : [ { "start" : 259, "end" : 292, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 157, "end" : 223, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 3.4E-10, "score" : 41.6, "model-ac" : "4hkqA02" }, { "signature" : { "accession" : "PTHR22955:SF60", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 84, "end" : 718, "hmmStart" : 548, "hmmEnd" : 1129, "hmmLength" : 1456, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 53, "envelopeEnd" : 727, "location-fragments" : [ { "start" : 84, "end" : 718, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 5.5E-151, "familyName" : "", "score" : 507.5, "model-ac" : "PTHR22955:SF60" }, { "signature" : { "accession" : "SSF56672", "name" : "DNA/RNA polymerases", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR043502", "name" : "DNA/RNA_pol_sf", "description" : "DNA/RNA polymerase superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 152, "end" : 597, "hmmLength" : 426, "location-fragments" : [ { "start" : 152, "end" : 597, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.67E-26, "model-ac" : "0044909" }, { "signature" : { "accession" : "mobidb-lite", "name" : "disorder_prediction", "description" : "consensus disorder prediction", "signatureLibraryRelease" : { "library" : "MOBIDB_LITE", "version" : "2.0" }, "entry" : null }, "locations" : [ { "start" : 717, "end" : 738, "location-fragments" : [ { "start" : 717, "end" : 738, "dc-status" : "CONTINUOUS" } ], "sequence-feature" : "" } ], "model-ac" : "mobidb-lite" }, { "signature" : { "accession" : "G3DSA:3.30.70.270", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : { "accession" : "IPR043128", "name" : "Rev_trsase/Diguanyl_cyclase", "description" : "Reverse transcriptase/Diguanylate cyclase domain", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 224, "end" : 359, "hmmStart" : 25, "hmmEnd" : 199, "hmmLength" : 144, "hmmBounds" : "INCOMPLETE", "evalue" : 6.6E-10, "score" : 40.7, "envelopeStart" : 139, "envelopeEnd" : 363, "postProcessed" : true, "location-fragments" : [ { "start" : 293, "end" : 359, "dc-status" : "N_TERMINAL_DISC" }, { "start" : 224, "end" : 258, "dc-status" : "C_TERMINAL_DISC" } ] } ], "evalue" : 3.4E-10, "score" : 41.6, "model-ac" : "4hkqA01" }, { "signature" : { "accession" : "PF05380", "name" : "Peptidase_A17", "description" : "Pao retrotransposon peptidase", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR008042", "name" : "Retrotrans_Pao", "description" : "Retrotransposon, Pao", "type" : "FAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 416, "end" : 578, "hmmStart" : 1, "hmmEnd" : 162, "hmmLength" : 162, "hmmBounds" : "COMPLETE", "evalue" : 1.3E-50, "score" : 171.6, "envelopeStart" : 416, "envelopeEnd" : 578, "postProcessed" : true, "location-fragments" : [ { "start" : 416, "end" : 578, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 6.0E-51, "score" : 172.7, "model-ac" : "PF05380" } ], "xref" : [ { "name" : "XP_018910134.1 PREDICTED: uncharacterized protein LOC109039196 [Bemisia tabaci]", "id" : "XP_018910134.1" } ] },{ "sequence" : "MPSVCDDIIDAEVNGEPPPGDFQKFTDEQAEAVERKLLKRKQRLYQLIAKSDSKALREEALQHGLIDDDVRSKAWPLLLDLKDLPDWDNISGEELESHHEYNQVVLDVNRSIKRFPPSIEDSRRIAIQDELIATIVTILSRNPGLHYYQGFHDVAVTILLVVKSKMAGHIIEKISTEHLKPFLEPTMERTSSLLEYIYPILEKIDLDLCKHLDRSGVGTIFCLPWFITWFSHTIEVYETLMRLFDYFLAYDHKPGTEFLLPLYLIVSILEHWKDDILEQECEMAALHSFFYRPLDTLDFEMLLKKADRYYHSYPPESMKKAVEKRIKDKEERQRLEDLERKALRERRLRPKAPNTPWMRRLTVVAIGVVFVLSSVYYARALLSWIKSRVLSVCKCKCIEMPISNWRTRNRRNVVAPAETELVGQ", "md5" : "6f87ee0c2ef0ec8a57a8a64553fd1908", "matches" : [ { "signature" : { "accession" : "PF00566", "name" : "RabGAP-TBC", "description" : "Rab-GTPase-TBC domain", "signatureLibraryRelease" : { "library" : "PFAM", "version" : "33.1" }, "entry" : { "accession" : "IPR000195", "name" : "Rab-GTPase-TBC_dom", "description" : "Rab-GTPase-TBC domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 68, "end" : 277, "hmmStart" : 1, "hmmEnd" : 215, "hmmLength" : 215, "hmmBounds" : "COMPLETE", "evalue" : 3.8E-26, "score" : 92.1, "envelopeStart" : 68, "envelopeEnd" : 277, "postProcessed" : true, "location-fragments" : [ { "start" : 68, "end" : 277, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 2.2E-26, "score" : 92.9, "model-ac" : "PF00566" }, { "signature" : { "accession" : "G3DSA:1.10.8.1310", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 23, "end" : 175, "hmmStart" : 11, "hmmEnd" : 157, "hmmLength" : 157, "hmmBounds" : "COMPLETE", "evalue" : 1.2E-39, "score" : 137.5, "envelopeStart" : 23, "envelopeEnd" : 175, "postProcessed" : true, "location-fragments" : [ { "start" : 23, "end" : 175, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.2E-39, "score" : 137.5, "model-ac" : "4hl4A01" }, { "signature" : { "accession" : "PS50086", "name" : "TBC_RABGAP", "description" : "TBC/rab GAP domain profile.", "signatureLibraryRelease" : { "library" : "PROSITE_PROFILES", "version" : "2019_11" }, "entry" : { "accession" : "IPR000195", "name" : "Rab-GTPase-TBC_dom", "description" : "Rab-GTPase-TBC domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 65, "end" : 251, "score" : 22.291, "alignment" : "LIDDDVRSKAWPLLLDLKDLPDWDNISGEELESHHEYN-------QVVLDVNRSIKRFPPSIEDSRRIAIQdeLIATIVTILSRNPGLHYYQGFHDVAVTILLVVKSkmaghiiEKISTEHLKPFLEPTMER---------TSSLLEYIYPILEKIDLDLCKHLDRSGVGTI-FCLPWFITWFSHTIEvYETLMRLFDYFLAYD", "location-fragments" : [ { "start" : 65, "end" : 251, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "PS50086" }, { "signature" : { "accession" : "G3DSA:1.10.472.80", "name" : "", "description" : null, "signatureLibraryRelease" : { "library" : "GENE3D", "version" : "4.2.0" }, "entry" : null }, "locations" : [ { "start" : 176, "end" : 316, "hmmStart" : 3, "hmmEnd" : 134, "hmmLength" : 135, "hmmBounds" : "COMPLETE", "evalue" : 4.0E-35, "score" : 122.5, "envelopeStart" : 176, "envelopeEnd" : 316, "postProcessed" : true, "location-fragments" : [ { "start" : 176, "end" : 316, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 4.0E-35, "score" : 122.5, "model-ac" : "4hl4A02" }, { "signature" : { "accession" : "Coil", "name" : "Coil", "description" : null, "signatureLibraryRelease" : { "library" : "COILS", "version" : "2.2.1" }, "entry" : null }, "locations" : [ { "start" : 318, "end" : 341, "location-fragments" : [ { "start" : 318, "end" : 341, "dc-status" : "CONTINUOUS" } ] } ], "model-ac" : "Coil" }, { "signature" : { "accession" : "PTHR20913", "name" : "TBC1 DOMAIN FAMILY MEMBER 20/GTPASE", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 51, "end" : 346, "hmmStart" : 30, "hmmEnd" : 320, "hmmLength" : 382, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 24, "envelopeEnd" : 354, "location-fragments" : [ { "start" : 51, "end" : 346, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-73, "familyName" : "ZGC:63863", "score" : 249.7, "model-ac" : "PTHR20913" }, { "signature" : { "accession" : "SM00164", "name" : "tbc_4", "description" : null, "signatureLibraryRelease" : { "library" : "SMART", "version" : "7.1" }, "entry" : { "accession" : "IPR000195", "name" : "Rab-GTPase-TBC_dom", "description" : "Rab-GTPase-TBC domain", "type" : "DOMAIN", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 62, "end" : 280, "hmmStart" : 1, "hmmEnd" : 310, "hmmLength" : 310, "hmmBounds" : "COMPLETE", "evalue" : 1.6E-4, "score" : 14.5, "location-fragments" : [ { "start" : 62, "end" : 280, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.6E-4, "score" : 14.5, "model-ac" : "SM00164" }, { "signature" : { "accession" : "PTHR20913:SF11", "name" : "ZGC:63863", "description" : null, "signatureLibraryRelease" : { "library" : "PANTHER", "version" : "14.1" }, "entry" : null }, "locations" : [ { "start" : 51, "end" : 346, "hmmStart" : 30, "hmmEnd" : 320, "hmmLength" : 382, "hmmBounds" : "INCOMPLETE", "envelopeStart" : 24, "envelopeEnd" : 354, "location-fragments" : [ { "start" : 51, "end" : 346, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.2E-73, "familyName" : "ZGC:63863", "score" : 249.7, "model-ac" : "PTHR20913:SF11" }, { "signature" : { "accession" : "SSF47923", "name" : "Ypt/Rab-GAP domain of gyp1p", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035969", "name" : "Rab-GTPase_TBC_sf", "description" : "Rab-GTPase-TBC domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 193, "end" : 313, "hmmLength" : 188, "location-fragments" : [ { "start" : 193, "end" : 313, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 3.4E-17, "model-ac" : "0037638" }, { "signature" : { "accession" : "SSF47923", "name" : "Ypt/Rab-GAP domain of gyp1p", "description" : null, "signatureLibraryRelease" : { "library" : "SUPERFAMILY", "version" : "1.75" }, "entry" : { "accession" : "IPR035969", "name" : "Rab-GTPase_TBC_sf", "description" : "Rab-GTPase-TBC domain superfamily", "type" : "HOMOLOGOUS_SUPERFAMILY", "goXRefs" : [ ], "pathwayXRefs" : [ ] } }, "locations" : [ { "start" : 61, "end" : 211, "hmmLength" : 194, "location-fragments" : [ { "start" : 61, "end" : 211, "dc-status" : "CONTINUOUS" } ] } ], "evalue" : 1.39E-15, "model-ac" : "0046806" } ], "xref" : [ { "name" : "XP_018909865.1 PREDICTED: TBC1 domain family member 20 isoform X1 [Bemisia tabaci]", "id" : "XP_018909865.1" } ] },{ "sequence" : "MQTSLLTLLILSTWTASCQSQKCGWFGVYCGRKRACEGYDLVYMDRHHGECDDDGVSFCCPKGEGTPVVFCTGPNRGGDCRVTFIPPGEDCAELPRDNNTNHIHEARSMMTRGACVRLWRALGCKGKTKLYNVGDENFVNTDDMPKALSVSPCFKNDKVIQMCKKQRYAGISKRAIDLNCNNIILGTANRPIEGPARFARDELFIGANESLIQQNVPDRNSPIRWIQFGPGGRTQALEALIEERHLGTGTAASNAARQFTAQHGYQGNPRDDAGHILDR