Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_018909617.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_018905426.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018907886.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018897683.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018914757.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_018915275.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_018904976.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018895698.1 4 KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963 "Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I" XP_018906811.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_018904263.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_018906357.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018911130.1 13 KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_018917116.1 10 MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13 "Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism" XP_018903065.1 11 KEGG: 00720+1.1.1.42;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-5913;MetaCyc: PWY-7268;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-7124;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.42 "Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)" XP_018917243.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_018905277.1 9 Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-380972 "Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"Neutrophil degranulation";"mTOR signalling";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_018911538.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018903268.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_018907854.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_018907971.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018908151.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018895780.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018913330.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018903302.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_018899702.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-5660862 "Basigin interactions";"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)" XP_018917793.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018897972.1 6 KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685 "Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"Peroxisomal protein import";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species" XP_018902068.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018917064.1 10 MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-5826 "Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis" XP_018901308.1 8 Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;MetaCyc: PWY-7524 "Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)" XP_018917745.1 4 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69205 "Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription" XP_018904563.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_018910574.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018904162.1 4 KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2 "Selenocompound metabolism";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_018900912.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_018906958.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_018915753.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018903378.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_018899968.1 9 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_018917696.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_018905701.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018912079.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695 "Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation" XP_018896608.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018910593.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_018902356.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_018899089.1 4 Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118 "SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation" XP_018907914.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_018914362.1 5 Reactome: R-HSA-4641257;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5689880 "Degradation of AXIN";"Protein ubiquitination";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases" XP_018914642.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018907152.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_018916923.1 8 Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor" XP_018908560.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018912551.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_018914936.1 7 Reactome: R-HSA-4086400;Reactome: R-HSA-201688;Reactome: R-HSA-5663220;Reactome: R-HSA-201681;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258 "PCP/CE pathway";"WNT mediated activation of DVL";"RHO GTPases Activate Formins";"TCF dependent signaling in response to WNT";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL" XP_018904288.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018908942.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_018914793.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018912482.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_018899334.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018903453.1 3 KEGG: 00791+3.5.1.54;KEGG: 00970+6.3.5.7;KEGG: 00220+3.5.1.54 "Atrazine degradation";"Aminoacyl-tRNA biosynthesis";"Arginine biosynthesis" XP_018915173.1 22 Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5358752 "Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated" XP_018909920.1 1 Reactome: R-HSA-916853 "Degradation of GABA" XP_018908604.1 12 KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5132;MetaCyc: PWY-5108;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118 "Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Methane metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Chitin degradation to ethanol" XP_018904597.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_018906833.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018917144.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_018916960.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_018914136.1 6 MetaCyc: PWY-4381;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-5744;Reactome: R-HSA-196780 "Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Biotin transport and metabolism" XP_018916225.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018908431.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_018905403.1 3 MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78 "3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_018906875.1 5 Reactome: R-HSA-2426168;MetaCyc: PWY-7072;Reactome: R-HSA-191273;MetaCyc: PWY-6098;KEGG: 00909+4.2.1.129+5.4.99.17 "Activation of gene expression by SREBF (SREBP)";"Hopanoid biosynthesis (bacteria)";"Cholesterol biosynthesis";"Diploterol biosynthesis";"Sesquiterpenoid and triterpenoid biosynthesis" XP_018911508.1 6 Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_018897381.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018897478.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018896137.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018914495.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_018903269.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_018911905.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018913851.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018902422.1 12 MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5857;MetaCyc: PWY-5856 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)" XP_018914845.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131 "MHC class II antigen presentation";"Collagen degradation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR" XP_018898650.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_018895579.1 2 Reactome: R-HSA-9616222;Reactome: R-HSA-381340 "Transcriptional regulation of granulopoiesis";"Transcriptional regulation of white adipocyte differentiation" XP_018910451.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_018915802.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_018905821.1 4 MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817 "Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_018917778.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_018899196.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-6142 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_018906515.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_018917685.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_018898246.1 10 MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6317;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;MetaCyc: PWY-7328 "D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis" XP_018918139.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018914737.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018905917.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018896603.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_018907142.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_018916947.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018908938.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_018896850.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018897771.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress" XP_018917514.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_018897756.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_018916311.1 5 KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_018917239.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_018908290.1 4 MetaCyc: PWY-7614;Reactome: R-HSA-2022377;MetaCyc: PWY-5706;MetaCyc: PWY-5707 "Methiin metabolism";"Metabolism of Angiotensinogen to Angiotensins";"Alliin metabolism";"Propanethial S-oxide biosynthesis" XP_018897389.1 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" XP_018911164.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018912414.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_018904020.1 17 Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_018910061.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_018914919.1 15 Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-5358752;Reactome: R-HSA-111465 "Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins" XP_018912291.1 5 Reactome: R-HSA-2426168;KEGG: 00100+2.5.1.21;KEGG: 00909+2.5.1.21;Reactome: R-HSA-191273;Reactome: R-HSA-1989781 "Activation of gene expression by SREBF (SREBP)";"Steroid biosynthesis";"Sesquiterpenoid and triterpenoid biosynthesis";"Cholesterol biosynthesis";"PPARA activates gene expression" XP_018901461.1 8 MetaCyc: PWY-6457;KEGG: 00360+4.3.1.24;MetaCyc: PWY-5048;Reactome: R-HSA-70921;MetaCyc: PWY-1121;KEGG: 00940+4.3.1.24;MetaCyc: PWY-5883;MetaCyc: PWY-6444 "Cinnamoyl-coa biosynthesis";"Phenylalanine metabolism";"Rosmarinic acid biosynthesis I";"Histidine catabolism";"Suberin monomers biosynthesis";"Phenylpropanoid biosynthesis";"Ephedrine biosynthesis";"Benzoate biosynthesis II (CoA-independent, non-beta-oxidative)" XP_018905570.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_018905089.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_018909016.1 14 MetaCyc: PWY-7901;MetaCyc: PWY-6842;KEGG: 00450+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-801;MetaCyc: PWY-2821;Reactome: R-HSA-8964539;MetaCyc: PWY-6309;MetaCyc: PWY-6936;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;Reactome: R-HSA-8964208;KEGG: 00380+2.6.1.7 "Glucosinolate biosynthesis from tyrosine";"Glutathione-mediated detoxification II";"Selenocompound metabolism";"Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Glutamate and glutamine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Phenylalanine metabolism";"Tryptophan metabolism" XP_018897083.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_018908340.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018896115.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018917717.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018905908.1 7 Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Pyruvate metabolism" XP_018907699.1 12 KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-418885;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Relaxin signaling pathway";"Rho GTPase cycle";"DCC mediated attractive signaling";"mTOR signaling pathway";"NRAGE signals death through JNK";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis" XP_018902224.1 6 KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6922 "Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis" XP_018897132.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_018913560.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018903987.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018901131.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_018913856.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018915097.1 9 KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-7385;MetaCyc: PWY-7411 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)" XP_018905097.1 2 MetaCyc: PWY-7380;KEGG: 00780+6.3.3.3 "Biotin biosynthesis from 8-amino-7-oxononanoate II";"Biotin metabolism" XP_018913813.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018910967.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018906825.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_018906312.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER" XP_018908235.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_018914646.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018917220.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_018914390.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018906827.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018899430.1 10 Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00710+2.7.2.3;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-8004 "Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I" XP_018904163.1 4 KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Selenocompound metabolism" XP_018900536.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_018912005.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018914099.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018901163.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_018915882.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_018899473.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_018914679.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018906840.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018914465.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018903481.1 17 KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8953750;Reactome: R-HSA-69601;Reactome: R-HSA-75035;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-1433557 "Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Human cytomegalovirus infection";"G2/M DNA damage checkpoint";"Thermogenesis";"mTOR signaling pathway";"Transcriptional Regulation by E2F6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"Processing of DNA double-strand break ends";"Signaling by SCF-KIT" XP_018915964.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_018899904.1 6 KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565;KEGG: 04658+3.1.3.16;Reactome: R-HSA-8939211;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Th1 and Th2 cell differentiation";"ESR-mediated signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018908012.1 3 Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport" XP_018910556.1 14 MetaCyc: PWY-5497;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-1622;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-2161;MetaCyc: PWY-181;KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1 "Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Methane metabolism";"Metabolism of folate and pterines";"Formaldehyde assimilation I (serine pathway)";"Glycine betaine degradation II (mammalian)";"Folate transformations I";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Folate transformations II (plants)";"Folate polyglutamylation";"Photorespiration ";"Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism" XP_018917995.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018900049.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018910833.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018907999.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_018909653.1 4 MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6782861;MetaCyc: PWY-7286 "Methylwyosine biosynthesis";"Trna methylation (yeast)";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_018911341.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_018914863.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018916014.1 3 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway" XP_018912383.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018903394.1 5 MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_018908518.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018909344.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018908055.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_018917992.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_018903115.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_018910877.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_018910129.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018912262.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018901604.1 6 Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Biotin transport and metabolism" XP_018906114.1 14 Reactome: R-HSA-418217;MetaCyc: PWY-7039;Reactome: R-HSA-4086398;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-399997;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-434316;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;Reactome: R-HSA-500657;MetaCyc: PWY-8052 "G beta:gamma signalling through PLC beta";"Phosphatidate metabolism, as a signaling molecule";"Ca2+ pathway";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Acetylcholine regulates insulin secretion";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"2-arachidonoylglycerol biosynthesis" XP_018914611.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_018901898.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_018915764.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_018904253.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_018917687.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018896884.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_018904362.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018911280.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_018903111.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_018901870.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018898435.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_018905105.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_018913639.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_018910368.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_018908023.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_018909262.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018912009.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_018902182.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_018895782.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018900981.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018917955.1 18 KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6643 "Novobiocin biosynthesis";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism";"Arginine and proline metabolism";"Arginine biosynthesis";"Sulfolactate degradation III";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Coenzyme M biosynthesis II" XP_018899576.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria" XP_018912837.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_018912411.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018895594.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_018913450.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_018898702.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_018898947.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295 "Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"Collagen degradation";"MHC class II antigen presentation" XP_018908867.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_018911029.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_018902594.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_018907877.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_018900053.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018914568.1 30 Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-2644607;Reactome: R-HSA-5610785;Reactome: R-HSA-2894862;Reactome: R-HSA-8939902;Reactome: R-HSA-5684264;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-2122947;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-8854050;Reactome: R-HSA-1170546;Reactome: R-HSA-917937;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-69231 "Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"NOTCH1 Intracellular Domain Regulates Transcription";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Prolactin receptor signaling";"Iron uptake and transport";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Downstream TCR signaling";"Cyclin D associated events in G1" XP_018898157.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_018907223.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018907527.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_018913375.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018916710.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_018903083.1 17 Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-6782135 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Dual incision in TC-NER" XP_018902485.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_018902430.1 13 MetaCyc: PWY-7220;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7222 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_018904863.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080 "Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)" XP_018897210.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_018900365.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-937072 "MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_018904107.1 6 Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695 "Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation" XP_018915761.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_018909603.1 16 Reactome: R-HSA-6811558;Reactome: R-HSA-1236974;Reactome: R-HSA-1257604;Reactome: R-HSA-5603041;Reactome: R-HSA-975155;Reactome: R-HSA-975871;Reactome: R-HSA-9020702;Reactome: R-HSA-3134963;Reactome: R-HSA-5602498;Reactome: R-HSA-975110;Reactome: R-HSA-1810476;Reactome: R-HSA-5602680;Reactome: R-HSA-209543;Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-5603037 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ER-Phagosome pathway";"PIP3 activates AKT signaling";"IRAK4 deficiency (TLR2/4)";"MyD88 dependent cascade initiated on endosome";"MyD88 cascade initiated on plasma membrane";"Interleukin-1 signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR5)";"p75NTR recruits signalling complexes";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"IRAK4 deficiency (TLR5)" XP_018904982.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018917903.1 4 MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" XP_018897195.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_018900326.1 11 Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135 "Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER" XP_018916283.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913812.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018906654.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_018913248.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_018899887.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_018915629.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018909341.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018914524.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_018914302.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_018908354.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_018906078.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_018899763.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_018901266.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_018905708.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_018914507.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_018908432.1 12 KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-7901;MetaCyc: PWY-6309;MetaCyc: PWY-6936;MetaCyc: PWY-2821;MetaCyc: PWY-801;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;MetaCyc: PWY-1187 "Selenocompound metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from homomethionine" XP_018899551.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-210500 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle" XP_018904437.1 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" XP_018908117.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018909467.1 6 Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880 "DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Ub-specific processing proteases" XP_018904910.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_018913718.1 5 Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5610787 "Hedgehog 'on' state";"Activation of SMO";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state" XP_018906137.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018909401.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018896772.1 31 KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-7858;MetaCyc: PWY-5973;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-7664;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWYG-321;MetaCyc: PWY-8049;Reactome: R-HSA-9029558;MetaCyc: PWY-7746;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7723;MetaCyc: PWY-7663;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-5367;MetaCyc: PWY-5142;Reactome: R-HSA-2426168;MetaCyc: PWY-6282;MetaCyc: PWY-5994 "Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Cis-vaccenate biosynthesis";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mycobacterial sulfolipid biosynthesis";"Biotin metabolism";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis (animals and fungi, cytoplasm)" XP_018901648.1 14 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5620924;Reactome: R-HSA-9648025;Reactome: R-HSA-1632852;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-141444 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Intraflagellar transport";"EML4 and NUDC in mitotic spindle formation";"Macroautophagy";"Aggrephagy";"HCMV Early Events";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_018907537.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018916445.1 1 Reactome: R-HSA-201451 "Signaling by BMP" XP_018896403.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018904213.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018896803.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_018914786.1 5 Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442 "VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs" XP_018906056.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018907621.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_018918273.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018912802.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_018916357.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018907980.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_018912174.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018914488.1 12 Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6804756 "Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation" XP_018914398.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_018904248.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018910337.1 11 Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_018912243.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018916822.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018903008.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_018896216.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_018896780.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018903196.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_018903603.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_018909604.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018903608.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018899940.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" XP_018905385.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_018898210.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_018914935.1 7 Reactome: R-HSA-4086400;Reactome: R-HSA-201688;Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-4641262;Reactome: R-HSA-4641258;Reactome: R-HSA-201681 "PCP/CE pathway";"WNT mediated activation of DVL";"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of DVL";"TCF dependent signaling in response to WNT" XP_018906139.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018901268.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601 "Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_018910702.1 4 Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_018900160.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_018900061.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018902760.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018915099.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018904236.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018914808.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_018914891.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)" XP_018908293.1 6 MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22 "UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism" XP_018917343.1 13 MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-561;Reactome: R-HSA-71403 "Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)" XP_018916774.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018896307.1 18 KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00330+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383 "Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Arginine and proline metabolism";"Arginine biosynthesis";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_018899362.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018912324.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_018904036.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603 "Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine" XP_018898980.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_018916160.1 52 Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-5250924;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-76071;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73772 "MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"B-WICH complex positively regulates rRNA expression";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape" XP_018913940.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_018917373.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" XP_018905835.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018902543.1 7 MetaCyc: PWY-6605;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805;MetaCyc: PWY-6610;MetaCyc: PWY-7807;Reactome: R-HSA-74217;Reactome: R-HSA-6798695 "Adenine and adenosine salvage II";"Purine metabolism";"(aminomethyl)phosphonate degradation";"Adenine salvage";"Glyphosate degradation III";"Purine salvage";"Neutrophil degranulation" XP_018911399.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_018910080.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_018913373.1 14 Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167287 "RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery" XP_018905583.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_018907267.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_018903909.1 4 Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228 "Crosslinking of collagen fibrils";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix" XP_018898432.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_018912623.1 3 KEGG: 00040+3.1.1.11;MetaCyc: PWY-7246;MetaCyc: PWY-7248 "Pentose and glucuronate interconversions";"Pectin degradation I";"Pectin degradation II" XP_018916752.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-114608 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation" XP_018899708.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018895679.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018905632.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018907611.1 6 MetaCyc: PWY-5744;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-5743;MetaCyc: PWY-6722 "Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Candicidin biosynthesis" XP_018916682.1 14 KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-975634;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4 "Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Retinoid metabolism and transport";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism" XP_018908119.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018900577.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_018911008.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_018908113.1 6 MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_018906329.1 6 Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66 "Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism" XP_018915101.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_018901683.1 1 Reactome: R-HSA-419771 "Opsins" XP_018908743.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018909643.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_018917472.1 4 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism" XP_018906631.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018912791.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_018914220.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_018907420.1 26 Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-389977 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Mitotic Prometaphase";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway" XP_018903756.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018902993.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_018916646.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression" XP_018905912.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018903107.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_018915518.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_018907463.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901972.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_018897194.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018917074.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_018914859.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing" XP_018902339.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018902491.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_018917452.1 4 Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_018918123.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018912008.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_018904536.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_018898804.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_018911507.1 42 Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-9610379;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-73728;Reactome: R-HSA-5334118;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-3214815;Reactome: R-HSA-110328;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-1912408;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-73772;Reactome: R-HSA-5693571;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-9616222;Reactome: R-HSA-5625886;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-69473;Reactome: R-HSA-9609690;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-2559582;Reactome: R-HSA-171306 "Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Late Events";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"RNA Polymerase I Promoter Opening";"DNA methylation";"SUMOylation of chromatin organization proteins";"Meiotic synapsis";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"HDACs deacetylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"RNA Polymerase I Promoter Escape";"Nonhomologous End-Joining (NHEJ)";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"Transcriptional regulation of granulopoiesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Amyloid fiber formation";"G2/M DNA damage checkpoint";"HCMV Early Events";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"Packaging Of Telomere Ends" XP_018903512.1 5 KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403 "Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling" XP_018899117.1 5 KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-1222556;Reactome: R-HSA-392154 "Arginine biosynthesis";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase" XP_018916503.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_018899991.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163359 "G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation" XP_018899892.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_018915117.1 5 Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693571 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)" XP_018911090.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018897990.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_018908719.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018915924.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_018908522.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018910012.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_018914294.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018917376.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_018904898.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_018912632.1 3 MetaCyc: PWY-7248;MetaCyc: PWY-7246;KEGG: 00040+3.1.1.11 "Pectin degradation II";"Pectin degradation I";"Pentose and glucuronate interconversions" XP_018898982.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_018901788.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_018914531.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018898414.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_018912250.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_018904327.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018914278.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018902080.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_018897308.1 42 MetaCyc: PWY-6946;MetaCyc: PWY-7654;MetaCyc: PWY-7007;MetaCyc: PWY-6945;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-5138;MetaCyc: PWY-6435;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-7778;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-5136;MetaCyc: PWY-7216;MetaCyc: PWY-7094;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-6583;KEGG: 00903+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00360+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-6944;KEGG: 00410+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5789;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7401;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00930+4.2.1.17+1.1.1.35 "Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Geraniol degradation";"Propanoate metabolism";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"4-hydroxybenzoate biosynthesis III (plants)";"Carbon fixation pathways in prokaryotes";"Fermentation to 2-methylbutanoate";"Lysine degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"2-methylpropene degradation";"Butanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation II (plant peroxisome)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid salvage";"Butanoate metabolism";"Fatty acid elongation";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol I";"Limonene and pinene degradation";"Fatty acid degradation";"Benzoate degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Phenylalanine metabolism";"Toluene degradation";"Pyruvate fermentation to butanol II (engineered)";"Androstenedione degradation";"beta-Alanine metabolism";"Valine, leucine and isoleucine degradation";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Tryptophan metabolism";"Spodoptera littoralis pheromone biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Aminobenzoate degradation";"Methyl tert-butyl ether degradation";"Caprolactam degradation" XP_018910786.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_018896857.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018909201.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_018911746.1 5 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_018909079.1 4 MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183 "UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_018914184.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_018898444.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760 "snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation" XP_018917694.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_018898784.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_018904989.1 3 Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989 "TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" XP_018903831.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_018906535.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018904404.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018903021.1 10 Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508 "Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription" XP_018904384.1 5 MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109 "Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis" XP_018916796.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" XP_018906841.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018898407.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018898335.1 2 Reactome: R-HSA-114608;Reactome: R-HSA-2132295 "Platelet degranulation";"MHC class II antigen presentation" XP_018899613.1 7 KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4 "Glycerophospholipid metabolism";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism" XP_018900011.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018895894.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018915019.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018910043.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_018903539.1 18 KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922 "alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Synthesis of PA";"Arachidonic acid metabolism";"Acyl chain remodelling of PI" XP_018899024.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_018912181.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_018909756.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018910602.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_018897203.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_018916475.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_018917305.1 2 Reactome: R-HSA-6793080;Reactome: R-HSA-2151201 "rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis" XP_018914601.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_018902776.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_018900507.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018903036.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018911011.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_018906569.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_018911778.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018913930.1 3 Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282 "HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B" XP_018903397.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018900467.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER" XP_018917178.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018903789.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-76005 "Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+" XP_018905755.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_018897204.1 5 Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695 "RMTs methylate histone arginines";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling" XP_018910546.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_018897880.1 4 KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716 "Selenocompound metabolism";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_018904228.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_018903480.1 17 KEGG: 05163+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-8953750;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-75035;Reactome: R-HSA-69601;Reactome: R-HSA-1433557;Reactome: R-HSA-5693607;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Activation of ATR in response to replication stress";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Transcriptional Regulation by E2F6";"mTOR signaling pathway";"Thermogenesis";"G2/M DNA damage checkpoint";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Signaling by SCF-KIT";"Processing of DNA double-strand break ends";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_018910607.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957 "mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018900842.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_018906678.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018896778.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018901989.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_018915995.1 5 KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_018909367.1 4 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines" XP_018914953.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018908691.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_018900534.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_018914955.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018904579.1 6 KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_018908030.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018915993.1 5 MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_018897190.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_018906959.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_018906849.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018896771.1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis" XP_018912233.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913208.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-389661 "Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation" XP_018898628.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_018910029.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_018917555.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_018915693.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_018895660.1 21 MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7222;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7219;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7197 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation" XP_018901600.1 6 MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599 "Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_018914969.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018898075.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018898775.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_018912125.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018902864.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_018912406.1 11 Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938 "G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)" XP_018912698.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_018913855.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018899580.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018915638.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018896916.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913889.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018898741.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_018915571.1 14 Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-6798695;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-9017802 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3" XP_018917069.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_018898928.1 3 Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681 "Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling" XP_018903063.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_018901930.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018900512.1 9 Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-2173791;Reactome: R-HSA-3656535;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532 "TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 LBD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer" XP_018896580.1 8 Reactome: R-HSA-4641263;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-5340588;Reactome: R-HSA-373080;Reactome: R-HSA-4086398;Reactome: R-HSA-4608870;Reactome: R-HSA-8856828 "Regulation of FZD by ubiquitination";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"RNF mutants show enhanced WNT signaling and proliferation";"Class B/2 (Secretin family receptors)";"Ca2+ pathway";"Asymmetric localization of PCP proteins";"Clathrin-mediated endocytosis" XP_018902361.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_018907508.1 14 Reactome: R-HSA-5663220;Reactome: R-HSA-380259;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5620912;Reactome: R-HSA-2467813;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "RHO GTPases Activate Formins";"Loss of Nlp from mitotic centrosomes";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Anchoring of the basal body to the plasma membrane";"Separation of Sister Chromatids";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_018913783.1 6 Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5 "Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_018900231.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_018916988.1 9 MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-6147;MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16 "Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis" XP_018899539.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_018913304.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_018908832.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018901817.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6781827 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_018906544.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_018914672.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_018902330.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_018904436.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_018917819.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis" XP_018898073.1 6 Reactome: R-HSA-446199;Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-191273;KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391 "Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)" XP_018903421.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_018896381.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_018908114.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952 "Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions" XP_018904808.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565 "G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_018901387.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_018902384.1 5 Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532 "Pyrimidine catabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)" XP_018900823.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7 "Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis" XP_018916497.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_018900978.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_018915662.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1" XP_018909279.1 9 KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00130+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00270+2.6.1.5;KEGG: 00960+2.6.1.5 "Tyrosine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine catabolism";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis" XP_018915137.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_018914003.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_018917469.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018898163.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018895927.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018899461.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_018913737.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018900230.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_018913172.1 9 Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Neddylation" XP_018912337.1 10 Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-3214847 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones" XP_018905676.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018903015.1 6 MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-7442 "Guanosine nucleotides degradation III";"Purine metabolism";"Purine catabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis" XP_018899976.1 5 KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68 "N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate" XP_018903398.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018909460.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_018909433.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_018899729.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018912812.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018897323.1 26 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Kinesins";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Mitotic Prometaphase" XP_018909736.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_018913032.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_018899999.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018896975.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018907255.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_018911128.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_018915681.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018909220.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_018917938.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_018898328.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_018916886.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_018902399.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_018912396.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_018895713.1 9 KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-196780;Reactome: R-HSA-70263;MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-3371599;MetaCyc: PWY-6146 "Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Biotin transport and metabolism";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism" XP_018899329.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018914073.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969 "Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina" XP_018914409.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018904872.1 6 Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" XP_018912063.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_018901183.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018911721.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_018904289.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018897673.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018912172.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018901736.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_018900314.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8854214 "Macroautophagy";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs" XP_018902762.1 16 Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-167287 "RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"HIV elongation arrest and recovery" XP_018899435.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_018904977.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018906269.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_018903738.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_018916493.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018904918.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018906682.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_018904580.1 6 MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143 "Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis" XP_018913306.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_018896331.1 5 MetaCyc: PWY-7072;Reactome: R-HSA-2426168;MetaCyc: PWY-6098;KEGG: 00909+4.2.1.129+5.4.99.17;Reactome: R-HSA-191273 "Hopanoid biosynthesis (bacteria)";"Activation of gene expression by SREBF (SREBP)";"Diploterol biosynthesis";"Sesquiterpenoid and triterpenoid biosynthesis";"Cholesterol biosynthesis" XP_018908475.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_018915992.1 5 Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism" XP_018917143.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_018895641.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018910530.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_018902336.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018916361.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_018906970.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018915273.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-68884 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Mitotic Telophase/Cytokinesis" XP_018912276.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_018904486.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018903594.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_018905271.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018901602.1 6 Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" XP_018911626.1 33 Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-4570464 "SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins" XP_018904899.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_018905210.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018897777.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018899906.1 6 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Th1 and Th2 cell differentiation" XP_018918034.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018911474.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_018903521.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018917596.1 4 Reactome: R-HSA-6782315;Reactome: R-HSA-156581;Reactome: R-HSA-72764;Reactome: R-HSA-6790901 "tRNA modification in the nucleus and cytosol";"Methylation";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol" XP_018900366.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-937072 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_018906094.1 5 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-430039 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease" XP_018915990.1 5 MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_018915834.1 8 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2465910 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"MASTL Facilitates Mitotic Progression" XP_018910450.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_018908287.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly" XP_018897081.1 52 Reactome: R-HSA-73762;Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-76061;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-76071;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-749476 "RNA Polymerase I Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation" XP_018904307.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018899395.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018903207.1 4 Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_018903189.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018898617.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_018901075.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018902498.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72695 "Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex" XP_018913151.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018898129.1 10 KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11 "Methane metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis" XP_018909372.1 3 MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1 "(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation" XP_018911059.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_018907216.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018909958.1 6 MetaCyc: PWY-7391;Reactome: R-HSA-191273;KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;MetaCyc: PWY-6174;MetaCyc: PWY-922 "Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I" XP_018900733.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_018905324.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs" XP_018906981.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_018903984.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018914743.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_018910907.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_018908022.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_018901277.1 3 Reactome: R-HSA-8939236;Reactome: R-HSA-383280;Reactome: R-HSA-983231 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_018909009.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018908118.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018899893.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_018908173.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018896219.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_018916138.1 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_018896072.1 10 MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-6842 "Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II" XP_018908013.1 3 Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport" XP_018902496.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_018908387.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_018911110.1 3 Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859 "Protein methylation";"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade" XP_018899428.1 5 Reactome: R-HSA-111458;MetaCyc: PWY-4361;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112 "Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_018897896.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018914248.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis" XP_018916696.1 1 KEGG: 00500+3.2.1.39 "Starch and sucrose metabolism" XP_018909956.1 3 KEGG: 00510+2.4.1.267;Reactome: R-HSA-4724289;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_018913848.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018911383.1 5 Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018916904.1 3 Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161 "Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation" XP_018901534.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018912252.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_018908569.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_018896192.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_018906472.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_018905816.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_018907242.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018918130.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_018903775.1 10 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;KEGG: 04926+2.7.11.1;Reactome: R-HSA-201722 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"HATs acetylate histones";"Ub-specific processing proteases";"Relaxin signaling pathway";"Formation of the beta-catenin:TCF transactivating complex" XP_018911978.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_018910026.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_018902802.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_018906619.1 6 KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17 "Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway" XP_018902448.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_018897620.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018907622.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_018906225.1 5 Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108 "Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_018917734.1 5 KEGG: 00791+3.5.1.54+6.3.4.6;Reactome: R-HSA-3371599;MetaCyc: PWY-5703;KEGG: 00220+3.5.1.54+6.3.4.6;Reactome: R-HSA-196780 "Atrazine degradation";"Defective HLCS causes multiple carboxylase deficiency";"Urea degradation I";"Arginine biosynthesis";"Biotin transport and metabolism" XP_018911244.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018905428.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_018901761.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018901024.1 9 KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-416476 "Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events" XP_018897864.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018903148.1 2 Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "Formation of apoptosome";"Regulation of the apoptosome activity" XP_018917862.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_018896138.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018909737.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_018903781.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_018916815.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018909546.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018897466.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_018916393.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_018899597.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018901859.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_018907410.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018902729.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018897233.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018917046.1 11 Reactome: R-HSA-5663213;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-2029482;Reactome: R-HSA-917977;Reactome: R-HSA-4420097;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556 "RHO GTPases Activate WASPs and WAVEs";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Regulation of actin dynamics for phagocytic cup formation";"Transferrin endocytosis and recycling";"VEGFA-VEGFR2 Pathway";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes" XP_018910705.1 8 KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-6901;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-8086;KEGG: 00010+1.1.1.27 "Propanoate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glycolysis / Gluconeogenesis" XP_018904575.1 6 Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920 "Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)" XP_018902886.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_018917534.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_018900877.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_018896208.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470 "rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion" XP_018916166.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018896187.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080 "Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I" XP_018917411.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_018898611.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_018918218.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018905022.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018910842.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018909459.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_018907419.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_018898621.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_018897794.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" XP_018895710.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_018910088.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection" XP_018911530.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018902011.1 5 Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24 "DSCAM interactions";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"mTOR signaling pathway" XP_018917503.1 8 MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-7198;Reactome: R-HSA-499943 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates" XP_018900006.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018898468.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_018914109.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_018903788.1 6 Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13 "Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system" XP_018899867.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018917688.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018898910.1 9 Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-191859;Reactome: R-HSA-381340 "Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"snRNP Assembly";"Transcriptional regulation of white adipocyte differentiation" XP_018910637.1 8 KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1 "Galactose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis" XP_018900892.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_018903042.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018900759.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_018915564.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_018914111.1 5 Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856825 "EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Gap junction degradation";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis" XP_018911509.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018917478.1 4 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_018901542.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018907253.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018915020.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018901715.1 4 KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801 "Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion" XP_018909803.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018911977.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_018909855.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018917530.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_018902589.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018898691.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism" XP_018910509.1 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II" XP_018913271.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018912087.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018899263.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018915449.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_018895914.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018906696.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-6142 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_018913777.1 8 Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Dual incision in TC-NER" XP_018898267.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018906546.1 3 Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153 "eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis" XP_018902955.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_018898347.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018916201.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018901204.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_018910341.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018898074.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018907297.1 5 Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "Sialic acid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation" XP_018899872.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_018904758.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018900068.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_018900765.1 8 Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174430 "Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation" XP_018911502.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018903128.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_018902928.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity" XP_018917796.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018901393.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018915683.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018914609.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_018901192.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" XP_018908435.1 14 MetaCyc: PWY-601;MetaCyc: PWY-801;Reactome: R-HSA-8964539;MetaCyc: PWY-2821;MetaCyc: PWY-6309;MetaCyc: PWY-6936;MetaCyc: PWY-7901;MetaCyc: PWY-6842;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;Reactome: R-HSA-8964208;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13 "Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Glutamate and glutamine metabolism";"Glucosinolate biosynthesis from phenylalanine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tyrosine";"Glutathione-mediated detoxification II";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Phenylalanine metabolism";"Tryptophan metabolism";"Tryptophan catabolism";"Cysteine and methionine metabolism" XP_018899458.1 12 KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7238;Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-3801;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9 "Glycerolipid metabolism";"Glycogen synthesis";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Stachyose degradation";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_018909196.1 3 MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_018896799.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_018907126.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018904385.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018917948.1 9 KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883 "Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II" XP_018907501.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018897535.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_018903992.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018905915.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018906477.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_018914470.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_018899030.1 14 Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944 "Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2" XP_018916900.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018909677.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_018903006.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_018906836.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018907985.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation" XP_018898245.1 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" XP_018903293.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018915996.1 5 KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_018906929.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018896409.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018908231.1 15 Reactome: R-HSA-9665250;Reactome: R-HSA-1227986;Reactome: R-HSA-9665251;Reactome: R-HSA-5637810;Reactome: R-HSA-9665245;Reactome: R-HSA-9664565;Reactome: R-HSA-9665233;Reactome: R-HSA-8863795;Reactome: R-HSA-9665249;Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-9634285;Reactome: R-HSA-9665247;Reactome: R-HSA-9665244;Reactome: R-HSA-1236382 "Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to tesevatinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to trastuzumab";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants" XP_018916987.1 9 KEGG: 00790+3.5.4.16;MetaCyc: PWY-5663;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-6703;MetaCyc: PWY-6147;MetaCyc: PWY-7852 "Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)" XP_018916032.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_018895853.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_018907389.1 5 Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131 "Collagen degradation";"MHC class II antigen presentation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR" XP_018897059.1 5 MetaCyc: PWY-7072;Reactome: R-HSA-2426168;KEGG: 00909+4.2.1.129+5.4.99.17;MetaCyc: PWY-6098;Reactome: R-HSA-191273 "Hopanoid biosynthesis (bacteria)";"Activation of gene expression by SREBF (SREBP)";"Sesquiterpenoid and triterpenoid biosynthesis";"Diploterol biosynthesis";"Cholesterol biosynthesis" XP_018911751.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37 "NoRC negatively regulates rRNA expression";"DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism" XP_018899271.1 17 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018903043.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018897928.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018901659.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018905774.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_018898669.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018916893.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_018917238.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_018913860.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018913324.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_018916301.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_018904981.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018909501.1 3 Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence" XP_018908229.1 4 Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion" XP_018896914.1 10 Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23 "HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Neutrophil degranulation";"Other glycan degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism" XP_018900484.1 9 Reactome: R-HSA-1362277;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "Transcription of E2F targets under negative control by DREAM complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_018911406.1 3 Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_018897391.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_018901128.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018917190.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_018911975.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_018906383.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018910904.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_018898299.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018904862.1 7 Reactome: R-HSA-8950505;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-390471 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis" XP_018913767.1 16 Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519 "Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression" XP_018900407.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA" XP_018903199.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" XP_018913312.1 4 Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202 "Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition" XP_018915172.1 22 Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated" XP_018908520.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018904995.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018903197.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_018898898.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018905621.1 18 Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648 "Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes" XP_018909616.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_018901243.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_018916903.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_018895631.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018910878.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_018901042.1 14 Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593 "Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity" XP_018900468.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER" XP_018913386.1 5 KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341 "Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)" XP_018906015.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018895768.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_018898633.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018896510.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_018903786.1 6 Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993 "G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors" XP_018913996.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_018912204.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_018915513.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_018898824.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018910231.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_018916430.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_018915001.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018900159.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_018896418.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018903771.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018895728.1 56 Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603 "ER-Phagosome pathway";"Degradation of DVL";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"UCH proteinases" XP_018913759.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs" XP_018896847.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018898139.1 10 MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism" XP_018909268.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018911535.1 5 KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234;Reactome: R-HSA-73817 "Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis" XP_018906680.1 57 Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-75815 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D" XP_018911125.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018896194.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_018916995.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018899265.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018915946.1 6 KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23 "Glycosaminoglycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_018908679.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex" XP_018910912.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018905660.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913874.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI" XP_018904339.1 12 KEGG: 00630+6.4.1.3;KEGG: 00720+6.4.1.3;MetaCyc: PWY-7384;MetaCyc: PWY-5743;KEGG: 00640+6.4.1.3;MetaCyc: PWYG-321;MetaCyc: PWY-5789;Reactome: R-HSA-71032;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00280+6.4.1.3;MetaCyc: PWY-6728 "Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"3-hydroxypropanoate cycle";"Propanoate metabolism";"";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propionyl-CoA catabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Valine, leucine and isoleucine degradation";"Methylaspartate cycle" XP_018915055.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_018900508.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_018907572.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" YP_086811.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018900538.1 2 Reactome: R-HSA-2426168;Reactome: R-HSA-191273 "Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis" XP_018906896.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018906835.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018909078.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162 "Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape" XP_018902984.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_018918132.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018916733.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_018896180.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018902060.1 3 Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807 "Interleukin-20 family signaling";"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling" XP_018912244.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_018912341.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018903596.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_018911277.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018910777.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" XP_018903732.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_018917512.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_018907930.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018910338.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018897090.1 19 Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-8963901;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825 "LDL remodeling";"Scavenging by Class A Receptors";"Chylomicron remodeling";"Chylomicron assembly";"Chylomicron clearance";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"LDL clearance";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Post-translational protein phosphorylation";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis" XP_018917645.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_018897419.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_018899696.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018901426.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018917792.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits" XP_018910616.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_018917565.1 3 Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_018900217.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018917954.1 18 KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6642;MetaCyc: PWY-7115;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00220+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1 "Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism";"Sulfolactate degradation III";"Arginine biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism" XP_018907549.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018904537.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_018905675.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_018900287.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018899039.1 14 Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519 "MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression" XP_018900506.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_018906724.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_018916979.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_018906184.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_018906423.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_018901451.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_018909710.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_018908640.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018915017.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018902328.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_018911165.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018912285.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_018895657.1 21 MetaCyc: PWY-7205;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7219;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7197 "CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation" XP_018916991.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018896508.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_018916535.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_018910528.1 28 Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-3371453;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-912446;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-3371511;Reactome: R-HSA-110320;Reactome: R-HSA-69166;Reactome: R-HSA-5696395;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616 "HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Meiotic recombination";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"HSF1 activation";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_018907040.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018910031.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_018915458.1 2 Reactome: R-HSA-2564830;Reactome: R-HSA-5693554 "Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_018901246.1 19 MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;Reactome: R-HSA-380320;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7205;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-7224 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Recruitment of mitotic centrosome proteins and complexes";"Purine deoxyribonucleosides salvage" XP_018905490.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_018896060.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_018897935.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_018906752.1 7 Reactome: R-HSA-446193;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356;MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis" XP_018913070.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_018913954.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018909894.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018916593.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018910228.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_018913748.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_018901498.1 7 Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis" XP_018907041.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-399997 "G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion" XP_018909544.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018909891.1 26 Reactome: R-HSA-5655862;Reactome: R-HSA-6804114;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-8866654;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-174414;Reactome: R-HSA-5656169;Reactome: R-HSA-69205;Reactome: R-HSA-174411;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-4615885;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-1362277;Reactome: R-HSA-110320;Reactome: R-HSA-174437 "Translesion synthesis by POLK";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Processive synthesis on the C-strand of the telomere";"Termination of translesion DNA synthesis";"G1/S-Specific Transcription";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA replication proteins";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Transcription of E2F targets under negative control by DREAM complex";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate from the C-strand" XP_018900223.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018915648.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_018917605.1 7 Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921 "Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation" XP_018905690.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism" XP_018909190.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341 "mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors" XP_018914434.1 33 Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-69273;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-674695;Reactome: R-HSA-6796648 "Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes" XP_018917949.1 9 KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_018903218.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018897776.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018903854.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_018896641.1 4 MetaCyc: PWY-7383;MetaCyc: PWY-8040;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1 "Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"Alanine racemization";"D-Alanine metabolism" XP_018901672.1 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_018917885.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_018916964.1 4 MetaCyc: PWY-2942;MetaCyc: PWY-2941;KEGG: 00300+4.1.1.20;MetaCyc: PWY-5097 "L-lysine biosynthesis III";"L-lysine biosynthesis II";"Lysine biosynthesis";"L-lysine biosynthesis VI" XP_018900754.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018911501.1 11 KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-381;Reactome: R-HSA-210455;MetaCyc: PWY-6549;Reactome: R-HSA-8964539 "Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism" XP_018914253.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_018914356.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018907780.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018902677.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_018909177.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-8934903 "Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy" XP_018913253.1 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_018907232.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018905395.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018897198.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "Neutrophil degranulation";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" XP_018895925.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_018903776.1 10 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04926+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Ub-specific processing proteases";"Relaxin signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Human cytomegalovirus infection" XP_018915432.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_018905682.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018900646.1 1 KEGG: 00910+4.2.1.104 "Nitrogen metabolism" XP_018915249.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018901666.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018900381.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018903399.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018901928.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_018900987.1 12 KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25 "Sulfur metabolism";"Transport and synthesis of PAPS";"Selenate reduction";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism";"Sulfate activation for sulfonation";"Monobactam biosynthesis";"Sulfite oxidation III";"Purine metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism" XP_018898681.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" XP_018911391.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018911359.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018915305.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_018904039.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" XP_018897729.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018914427.1 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" XP_018901175.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018908394.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_018909647.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_018910723.1 8 MetaCyc: PWY-66;KEGG: 00051+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5738;MetaCyc: PWY-7573;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5740;MetaCyc: PWY-5739 "GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-colitose biosynthesis";"GDP-D-perosamine biosynthesis" XP_018895981.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018896035.1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" XP_018917181.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018906424.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018907711.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018907740.1 32 Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6803529;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-77075 "Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE" XP_018911763.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_018915647.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_018905492.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_018897959.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_018896405.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018918026.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018911291.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018903038.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_018903393.1 6 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;MetaCyc: PWY-622;Reactome: R-HSA-3878781;MetaCyc: PWY-7900 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_018895684.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018909621.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_018899820.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_018897141.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_018902659.1 5 KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4 "Valine, leucine and isoleucine degradation";"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Butanoate metabolism" XP_018910966.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018916255.1 14 MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51 "CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Glycerolipid metabolism" XP_018906452.1 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_018899899.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_018902585.1 27 Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-180746 "Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein" XP_018907056.1 4 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_018902156.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_018913896.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018912520.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018900699.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_018906422.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_018904495.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018918233.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_018898901.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490 "Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"MHC class II antigen presentation";"Collagen degradation" XP_018904406.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_018904767.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_018914797.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018903276.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018907895.1 10 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04926+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Recycling pathway of L1";"Relaxin signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Human cytomegalovirus infection" XP_018901674.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_018904932.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018915276.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018915504.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_018896408.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018911168.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_018902854.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018904978.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018914841.1 17 MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-6609;Reactome: R-HSA-74259;MetaCyc: PWY-4202;MetaCyc: PWY-5532;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-5695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644 "Purine deoxyribonucleosides degradation II";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage III";"Purine catabolism";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Guanine and guanosine salvage";"Purine metabolism";"Adenine and adenosine salvage V";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis" XP_018913009.1 1 Reactome: R-HSA-5627083 "RHO GTPases regulate CFTR trafficking" XP_018895888.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018915066.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018897249.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_018899846.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018913052.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018906473.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_018901599.1 5 Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_018905785.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_018899894.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_018917679.1 19 Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-8963901;Reactome: R-HSA-8856825;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-381426 "Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Chylomicron assembly";"Chylomicron clearance";"LDL remodeling";"Scavenging by Class A Receptors";"Chylomicron remodeling";"Cargo recognition for clathrin-mediated endocytosis";"VLDL assembly";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"LDL clearance";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"VLDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_018906562.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018917359.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018896712.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_018907415.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_018913257.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619 "Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN" XP_018898354.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_018909620.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018896398.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018900993.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_018904510.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569 "Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_018914843.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295 "Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"Collagen degradation";"MHC class II antigen presentation" XP_018903427.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018905575.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_018896395.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018896979.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018901476.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_018904321.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018905260.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_018904817.1 19 KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-1622;MetaCyc: PWY-6969;MetaCyc: PWY-7383;MetaCyc: PWY-8086;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00720+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-561;Reactome: R-HSA-71403 "Methane metabolism";"Pyruvate metabolism";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)" XP_018911056.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018903441.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_018915442.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" XP_018898489.1 25 Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690 "Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"RHO GTPases Activate Formins";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Recycling pathway of L1";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"Kinesins";"RHO GTPases activate IQGAPs";"HCMV Early Events" XP_018900888.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_018898256.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_018897387.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_018905731.1 6 Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863 "RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination" XP_018901055.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_018910478.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_018897621.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018904879.1 17 Reactome: R-HSA-202424;Reactome: R-HSA-9014325;Reactome: R-HSA-5689880;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-5357956;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-975163;Reactome: R-HSA-168638 "Downstream TCR signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ub-specific processing proteases";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway" XP_018897625.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018895690.1 8 KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_018900054.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018912249.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_018900445.1 12 KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;MetaCyc: PWY-1187;MetaCyc: PWY-6842;KEGG: 00450+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-6936;MetaCyc: PWY-6309;MetaCyc: PWY-801;MetaCyc: PWY-601;MetaCyc: PWY-2821 "Cysteine and methionine metabolism";"Tryptophan catabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Selenocompound metabolism";"Glucosinolate biosynthesis from tyrosine";"Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from phenylalanine" XP_018914102.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_018900141.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_018909007.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018897454.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018917946.1 9 KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_018898803.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_018908129.1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295 "Glycosphingolipid metabolism";"Sialic acid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation" XP_018915401.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018905070.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018917174.1 7 Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628 "O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_018905921.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018918249.1 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_018911108.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018908123.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018897028.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018901440.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018899844.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_018899648.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018903440.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_018912301.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399 "SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Aggrephagy" XP_018915207.1 5 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Plasmalogen biosynthesis" XP_018898010.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018902808.1 57 Reactome: R-HSA-8939236;Reactome: R-HSA-532668;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome" XP_018918088.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018900744.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_018901927.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018906466.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018910739.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_018907257.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_018904611.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_018917084.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_018917983.1 6 MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-622 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis" XP_018917426.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_018915316.1 4 KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" XP_018918213.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018899895.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_018906581.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018914261.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_018908508.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018916050.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_018906903.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_018908645.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018898308.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018917075.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_018901913.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_018917780.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_018897867.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018901062.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018904540.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-264870 "Nephrin family interactions";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins" XP_018914958.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_018902221.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_018903044.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018909792.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_018907046.1 6 Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1" XP_018914340.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_018901496.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018900752.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018914762.1 12 KEGG: 00130+1.14.99.60;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-7230;MetaCyc: PWY-5873 "Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)" XP_018909339.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018909674.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_018914999.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018914517.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_018904896.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_018914733.1 3 Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018904520.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_018911127.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_018896178.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018911981.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_018895573.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018900767.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_018912707.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_018913431.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018903364.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018899029.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_018898697.1 10 MetaCyc: PWY-3841;MetaCyc: PWY-7210;Reactome: R-HSA-69205;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00240+2.1.1.45;Reactome: R-HSA-499943;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7199 "Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"One carbon pool by folate";"Pyrimidine deoxyribonucleosides salvage" XP_018896907.1 6 MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-7234 "Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III" XP_018901770.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_018916652.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018903131.1 3 Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11 "Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" XP_018895998.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018912891.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4570464 "SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins" XP_018895895.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018910147.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018900189.1 6 Reactome: R-HSA-983168;Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795 "Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling" XP_018903304.1 7 MetaCyc: PWY-5651;KEGG: 00380+1.13.11.6;Reactome: R-HSA-71240;Reactome: R-HSA-5620922;MetaCyc: PWY-6309;MetaCyc: PWY-6505;MetaCyc: PWY-5647 "L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"Tryptophan catabolism";"BBSome-mediated cargo-targeting to cilium";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation XII (Geobacillus)";"2-nitrobenzoate degradation I" XP_018901236.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_018910639.1 8 KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171 "Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Glycolysis" XP_018897080.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_018912878.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018896901.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_018909056.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018903035.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018896646.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;MetaCyc: PWY-7919 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)" XP_018896650.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;MetaCyc: PWY-7511 "mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Protein ubiquitination" XP_018901518.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_018901142.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_018898645.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_018917805.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER" XP_018917684.1 11 Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082 "RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression" XP_018904106.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018897705.1 10 MetaCyc: PWY-6317;MetaCyc: PWY-7344;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2 "D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"Galactose metabolism";"D-galactose detoxification";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism" XP_018900056.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018903133.1 3 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis" XP_018918217.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018900305.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_018915616.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_018904584.1 6 KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622 "Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)" XP_018897356.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018918127.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018905571.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_018901322.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_018901732.1 8 KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4661;MetaCyc: PWY-6372 "Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)" XP_018918049.1 34 Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-9639288;Reactome: R-HSA-159236 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amino acids regulate mTORC1";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_018916461.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_018899776.1 4 MetaCyc: PWY-5874;Reactome: R-HSA-189483;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18 "Heme degradation I";"Heme degradation";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism" XP_018906166.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018905248.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018904965.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018902784.1 9 Reactome: R-HSA-2029482;Reactome: R-HSA-5218920;Reactome: R-HSA-416482;Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-2871796 "Regulation of actin dynamics for phagocytic cup formation";"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"Rho GTPase cycle";"NRAGE signals death through JNK";"FCERI mediated MAPK activation" XP_018918022.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_018916202.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018897270.1 12 MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-6978;MetaCyc: PWY-5856;MetaCyc: PWY-5870;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5873;Reactome: R-HSA-1268020 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Mitochondrial protein import" XP_018912674.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_018906879.1 6 MetaCyc: PWY-7900;MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism" XP_018901274.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018908979.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018908338.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_018902436.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018900910.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_018908874.1 14 MetaCyc: PWY-7279;Reactome: R-HSA-611105;MetaCyc: PWY-6969;KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-4302 "Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)" XP_018911382.1 5 Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018908339.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018916168.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018897895.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018914077.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_018909629.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018898036.1 5 MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22 "Stachyose degradation";"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_018905160.1 8 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"mTOR signaling pathway" XP_018902363.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_018908093.1 14 Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5656169 "Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Termination of translesion DNA synthesis" XP_018899236.1 13 Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509 "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Ion homeostasis";"DAG and IP3 signaling" XP_018900894.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_018899225.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018899460.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I" XP_018904357.1 5 MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-6168;MetaCyc: PWY-7863 "5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis" XP_018899987.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018916775.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018905103.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_018901678.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018912521.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018906591.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018898683.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane" XP_018912546.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_018911109.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018909361.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_018909384.1 1 MetaCyc: PWY-6938 "NADH repair" XP_018897936.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_018905138.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018900517.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_018902883.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_018896886.1 31 Reactome: R-HSA-2426168;MetaCyc: PWY-5994;MetaCyc: PWY-6282;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-7723;MetaCyc: PWY-7663;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7858;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-7664;MetaCyc: PWYG-321;Reactome: R-HSA-199220;MetaCyc: PWY-8049;MetaCyc: PWY-6113;MetaCyc: PWY-7746;Reactome: R-HSA-9029558;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41 "Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"";"Vitamin B5 (pantothenate) metabolism";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Biotin metabolism" XP_018912999.1 7 KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7219;Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14 "Thiamine metabolism";"Drug metabolism - other enzymes";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine metabolism" XP_018909364.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_018917886.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_018901926.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018906146.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018899953.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_018916887.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_018903915.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018914052.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_018912803.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_018899515.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018918281.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018916770.1 11 MetaCyc: PWY-6999;MetaCyc: PWY-6607;MetaCyc: PWY-6606;MetaCyc: PWY-5695;MetaCyc: PWY-6596;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-6538;MetaCyc: PWY-5497;Reactome: R-HSA-8851680 "Theophylline degradation";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Butyrophilin (BTN) family interactions" XP_018897996.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_018908583.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_018914022.1 17 KEGG: 04151+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3371453 "PI3K-Akt signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Thermogenesis";"mTOR signaling pathway";"Meiotic synapsis";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Human cytomegalovirus infection";"Regulation of HSF1-mediated heat shock response" XP_018914865.1 3 KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" XP_018906615.1 6 MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17 "L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway" XP_018908039.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_018912392.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_018914478.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_018903564.1 17 KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;Reactome: R-HSA-196780;Reactome: R-HSA-163765;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381 "Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate assimilation";"Pyruvate metabolism";"Carnitine metabolism";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)" XP_018896096.1 10 Reactome: R-HSA-1855191;MetaCyc: PWY-6372;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6369 "Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_018917590.1 5 Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-6855;MetaCyc: PWY-5514 "Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_018909326.1 5 Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5649702;Reactome: R-HSA-110381;Reactome: R-HSA-5685939 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway";"HDR through MMEJ (alt-NHEJ)" XP_018900222.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_018911274.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018907445.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_018905126.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018912086.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018906618.1 6 MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17 "Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Pentose phosphate pathway" XP_018914028.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex" XP_018906416.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018917795.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018904487.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018908474.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_018914823.1 14 KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8055 "Ether lipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Synthesis of PC";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PE";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis" XP_018902694.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018899339.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018916299.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_018907670.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" XP_018914100.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018907101.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_018911408.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-113507 "Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation" XP_018911722.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018906465.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_018906278.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_018916615.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018917183.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_018895742.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_018910537.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018903390.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_018904503.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-114608 "MHC class II antigen presentation";"Platelet degranulation" XP_018913322.1 9 Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_018904247.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018916818.1 10 Reactome: R-HSA-2453864;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;MetaCyc: PWY-7394;MetaCyc: PWY-5691;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-3000171;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849 "Retinoid cycle disease events";"Neutrophil degranulation";"Amyloid fiber formation";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions";"Purine metabolism";"Urate conversion to allantoin III" XP_018911556.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018911178.1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" XP_018904285.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018903504.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_018905815.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_018915153.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018909790.1 4 Reactome: R-HSA-947581;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409 "Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis" XP_018915576.1 9 KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation" XP_018914374.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018917878.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_018898811.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease" XP_018900571.1 5 Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841 "Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"One carbon pool by folate";"Folate transformations II (plants)" XP_018909398.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_018909650.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_018901837.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168333 "HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_018911397.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_018913174.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_018900801.1 16 Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-201722;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-69473 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint" XP_018901700.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_018901915.1 5 MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317 "D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)" XP_018898810.1 3 KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456 "Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid" XP_018909644.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_018912813.1 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_018910598.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_018907471.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_018904663.1 26 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Mitotic Prometaphase" XP_018897616.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018898996.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295 "Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"MHC class II antigen presentation" XP_018911048.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018914554.1 13 Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52 "CS/DS degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation" XP_018897250.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_018902660.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018902982.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018899610.1 7 Reactome: R-HSA-1483166;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-3561;Reactome: R-HSA-2029485 "Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PG";"Choline biosynthesis III";"Role of phospholipids in phagocytosis" XP_018917435.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018917079.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_018907534.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_018899728.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018905064.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018909706.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018902954.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018917991.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_018901981.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_018910395.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018913959.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018897667.1 18 MetaCyc: PWY-7205;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7176 "CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis" XP_018896730.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_018904325.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018910738.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_018907177.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_018917529.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_018897424.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018910670.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-114608 "Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Platelet degranulation" XP_018901247.1 19 KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;Reactome: R-HSA-380270;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7221;Reactome: R-HSA-380320 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of mitotic centrosome proteins and complexes";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes" XP_018906537.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018901194.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" XP_018906467.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_018897778.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018900077.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018906999.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_018909399.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_018903184.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_018909902.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_018900438.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_018901045.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" XP_018898693.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_018896552.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018898532.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_018911389.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018909610.1 2 Reactome: R-HSA-6793080;Reactome: R-HSA-2151201 "rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis" XP_018900773.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" XP_018904901.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_018917737.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_018904287.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018901724.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_018916633.1 3 MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9 "Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis" XP_018905140.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018898770.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_018903562.1 17 KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744 "Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Carnitine metabolism";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Glyoxylate assimilation" XP_018899596.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018896389.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_018905745.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_018914722.1 9 Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;MetaCyc: PWY-6901;KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-8004 "Glycolysis";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Gluconeogenesis";"Entner-Doudoroff pathway I" XP_018918106.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018914112.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_018901150.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs" XP_018907138.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018916931.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018916843.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_018913357.1 2 KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_018900509.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_018915970.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_018898543.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159236 "Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_018915182.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_018918239.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018899456.1 12 KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7238;MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343 "Glycerolipid metabolism";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I" XP_018917740.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_018906369.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_018909083.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018911927.1 7 KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201 "Photosynthesis";"Mitochondrial protein import";"ATP biosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis" XP_018913543.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_018911184.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_018910995.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_018911183.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_018904420.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018912905.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_018912861.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_018916613.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_018914180.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_018912331.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_018903018.1 4 MetaCyc: PWY-4261;Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism" XP_018904314.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018917168.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018898208.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_018901452.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_018903549.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018906670.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape" XP_018917275.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_018899600.1 6 Reactome: R-HSA-110357;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-110362 "Displacement of DNA glycosylase by APEX1";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"POLB-Dependent Long Patch Base Excision Repair" XP_018912022.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018912661.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018906395.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" YP_086813.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_018897386.1 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" XP_018901317.1 7 MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25 "Phytate degradation I";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system" XP_018907673.1 12 Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-418885;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Rho GTPase cycle";"G alpha (q) signalling events";"Relaxin signaling pathway";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_018902334.1 3 Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases" XP_018902774.1 15 MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-7218 "Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_018917556.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_018913769.1 16 Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519 "Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression" XP_018911160.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018899513.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_018916732.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_018908689.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-1369062;Reactome: R-HSA-8964058 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis";"HDL remodeling" XP_018910427.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_018896879.1 8 KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288 "Photosynthesis";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Amino acids regulate mTORC1" XP_018895868.1 6 MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1 "Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Glycogen degradation II";"Starch degradation III";"Starch and sucrose metabolism" XP_018909873.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942 "Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism" XP_018905203.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_018903182.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_018897555.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_018897802.1 8 MetaCyc: PWY-1861;Reactome: R-HSA-163754;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;MetaCyc: PWY-5723;Reactome: R-HSA-6791055 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P" XP_018910692.1 24 Reactome: R-HSA-2730905;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-9634635;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-202424;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218921;KEGG: 04926+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-354192;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 04714+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-2871837 "Role of LAT2/NTAL/LAB on calcium mobilization";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Estrogen-stimulated signaling through PRKCZ";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"Downstream TCR signaling";"RSK activation";"Human cytomegalovirus infection";"VEGFR2 mediated cell proliferation";"Relaxin signaling pathway";"GPVI-mediated activation cascade";"Integrin signaling";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Thermogenesis";"Activation of AKT2";"FCERI mediated NF-kB activation" XP_018912289.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Intra-Golgi traffic" XP_018906167.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_018909675.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_018910303.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913719.1 5 Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5620922;Reactome: R-HSA-5610787;Reactome: R-HSA-373080 "Hedgehog 'on' state";"Activation of SMO";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state";"Class B/2 (Secretin family receptors)" XP_018916631.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018902950.1 15 Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-176408 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase" XP_018910655.1 4 Reactome: R-HSA-111465;Reactome: R-HSA-176187;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607 "Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress";"Ub-specific processing proteases";"Processing of DNA double-strand break ends" XP_018911744.1 4 KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_018895897.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018918191.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018911077.1 9 Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-1362300 "Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_018909434.1 52 Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-76071;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-5250924;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-6803529;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-73762 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"FGFR2 alternative splicing";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Initiation" XP_018900139.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_018912281.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_018905550.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_018903989.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_018913742.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-201681;MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751 "Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Protein ubiquitination";"Degradation of AXIN";"Regulation of PTEN stability and activity" XP_018911409.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_018914336.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_018917254.1 14 MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-3781;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6728;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;Reactome: R-HSA-611105;MetaCyc: PWY-7279 "Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)" XP_018911329.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_018906957.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_018911332.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_018896320.1 2 KEGG: 00230+3.6.1.66;Reactome: R-HSA-74259 "Purine metabolism";"Purine catabolism" XP_018916801.1 2 Reactome: R-HSA-5633231;Reactome: R-HSA-446193 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_018900059.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018914883.1 3 KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_018909901.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_018905353.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_018911131.1 13 KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_018896796.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_018913137.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" YP_086805.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_018909850.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018915794.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018897475.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_018899860.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_018895591.1 8 Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-164378 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"DARPP-32 events";"PKA activation";"PKA activation in glucagon signalling" XP_018915988.1 5 KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_018906924.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_018900876.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_018897502.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_018906075.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_018917080.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_018913205.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" XP_018901311.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018896782.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018913852.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018901940.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061 "Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I" XP_018910654.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_018906683.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_018902553.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_018917024.1 6 Reactome: R-HSA-5609978;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370 "Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism" XP_018916708.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_018906162.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_018900884.1 5 MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667 "Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I" XP_018904049.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_018898276.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018904541.1 7 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-6807878 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"COPI-mediated anterograde transport" XP_018896412.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018908375.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018908240.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage" XP_018896854.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018918008.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018914468.1 20 Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5693607;Reactome: R-HSA-110320 "Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH" XP_018906512.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_018898649.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018897638.1 4 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;Reactome: R-HSA-71737;MetaCyc: PWY-7805 "Oxidative phosphorylation";"Glyphosate degradation III";"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation" XP_018910674.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants" XP_018913382.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018902066.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018906826.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913880.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018901567.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913827.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018901456.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-4085377 "SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins" XP_018906079.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_018899305.1 9 Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324 "Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_018903507.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_018915221.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_018913859.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018895598.1 4 MetaCyc: PWY-6654;KEGG: 00410+6.3.2.1;KEGG: 00770+2.1.2.11;KEGG: 00770+6.3.2.1 "Phosphopantothenate biosynthesis III (archaebacteria)";"beta-Alanine metabolism";"Pantothenate and CoA biosynthesis";"Pantothenate and CoA biosynthesis" XP_018915111.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_018906945.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_018899612.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" XP_018917601.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018898090.1 10 KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385 "Methane metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)" XP_018917910.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_018913005.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_018905657.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018902598.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_018908973.1 3 KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3 "Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism" XP_018896530.1 5 MetaCyc: PWY-7072;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-6098;KEGG: 00909+4.2.1.129+5.4.99.17 "Hopanoid biosynthesis (bacteria)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Diploterol biosynthesis";"Sesquiterpenoid and triterpenoid biosynthesis" XP_018916582.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018895890.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018909690.1 5 Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68827 "G1/S-Specific Transcription";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex" XP_018896179.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018903005.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_018916797.1 1 Reactome: R-HSA-6804759 "Regulation of TP53 Activity through Association with Co-factors" XP_018898819.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_018913301.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018904651.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018915169.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018902112.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_018914717.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_018904012.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_018901838.1 27 Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-3232142 "Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins" XP_018900327.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_018896614.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018905328.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018899241.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_018916683.1 14 MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;Reactome: R-HSA-975634 "Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Retinoid metabolism and transport" XP_018899343.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_018895615.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018917865.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018911194.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018906175.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_018912408.1 3 KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_018896976.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018900682.1 6 MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I" XP_018905591.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation" XP_018899884.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018913483.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018897383.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_018898907.1 6 Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_018914494.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_018917553.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_018917947.1 9 KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation" XP_018896396.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018897866.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018900037.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841 "Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines" XP_018917189.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_018907043.1 6 Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1" XP_018897897.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018914862.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018906965.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_018901356.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_018901178.1 27 Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168271 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus" XP_018916488.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_018899639.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands" XP_018901731.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_018910571.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69205 "Polo-like kinase mediated events";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription" XP_018911396.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_018900261.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018904509.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway" XP_018917748.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018910997.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy" XP_018905645.1 7 Reactome: R-HSA-73817;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596;KEGG: 00230+1.1.1.205;MetaCyc: PWY-7221 "Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_018903152.1 57 Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590 "Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Neddylation";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling" XP_018911092.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018911384.1 5 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation" XP_018902108.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_018908233.1 58 Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-5689901;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590 "Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neutrophil degranulation";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Metalloprotease DUBs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling" XP_018902617.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_018918146.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018912474.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_018912839.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018901760.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018900052.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901455.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_018909509.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_018918092.1 3 MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493 "Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2" XP_018895892.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018897543.1 52 Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-76061;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-76071;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-73779;Reactome: R-HSA-167243;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-5250924;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-76066;Reactome: R-HSA-113418;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-5617472 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"HIV Transcription Initiation";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of the Early Elongation Complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_018907863.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361 "Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_018906311.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_018899523.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018904969.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_018900268.1 6 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-5632684 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog 'on' state" XP_018918014.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018915704.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018898629.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_018902364.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_018895652.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_018912484.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_018898103.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018915661.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_018906810.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_018915671.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_018914020.1 17 KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-1221632;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-3371453;Reactome: R-HSA-5685938;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Meiotic synapsis";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Regulation of HSF1-mediated heat shock response";"HDR through Single Strand Annealing (SSA)";"Human cytomegalovirus infection";"Thermogenesis";"G2/M DNA damage checkpoint";"mTOR signaling pathway" XP_018898927.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662 "Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism" XP_018908038.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018895602.1 3 Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807 "Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling" XP_018915065.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018902029.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018907054.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_018901689.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy" XP_018901167.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_018900582.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_018895980.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018908170.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018905345.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis" XP_018917162.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018912352.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_018910210.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018915147.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018906176.1 17 Reactome: R-HSA-174417;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-174414 "Telomere C-strand (Lagging Strand) Synthesis";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Processive synthesis on the C-strand of the telomere" XP_018902272.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_018915887.1 4 MetaCyc: PWY-6129;Reactome: R-HSA-4755583;Reactome: R-HSA-446199;KEGG: 00510+2.7.1.108 "Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" XP_018901296.1 7 MetaCyc: PWY-5129;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838;MetaCyc: PWY-7841;Reactome: R-HSA-1660662;MetaCyc: PWY-7836 "Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis" XP_018909853.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018909928.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_018904531.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_018901165.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_018905480.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_018916701.1 4 Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_018906949.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018916411.1 8 MetaCyc: PWY-7391;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7524;MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34 "Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis" XP_018901921.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018899008.1 6 Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363 "Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_018902009.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_018913842.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018900470.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005 "Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport" XP_018913317.1 4 Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69202 "Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition" XP_018900969.1 3 Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801 "Glutathione conjugation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)" XP_018906399.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_018905705.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018910402.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018911340.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018917492.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_018909351.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_018908481.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018898273.1 29 Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-6804757;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6803207;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-69541;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-349425;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-6803204;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;KEGG: 04714+2.7.11.1 "Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Degradation";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Human cytomegalovirus infection";"Regulation of HSF1-mediated heat shock response";"Stabilization of p53";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Sensing of DNA Double Strand Breaks";"Autodegradation of the E3 ubiquitin ligase COP1";"mTOR signaling pathway";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Thermogenesis" XP_018917957.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018897922.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_018899445.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_018917607.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease" XP_018903236.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018896616.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018899595.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018904264.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_018898771.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_018908068.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018918102.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018897947.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018914915.1 15 Reactome: R-HSA-111465;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-3769402;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337 "Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Deactivation of the beta-catenin transactivating complex";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding" XP_018911328.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_018917164.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018916749.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018911106.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_018900653.1 7 Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-381070 "Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones" XP_018900330.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_018916025.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-68884 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"Mitotic Telophase/Cytokinesis" XP_018915174.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220 "S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins" XP_018906136.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018904521.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_018917269.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_018897889.1 5 MetaCyc: PWY-7180;Reactome: R-HSA-71336;MetaCyc: PWY-8060;Reactome: R-HSA-6798695;KEGG: 00030+4.1.2.4 "2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"Neutrophil degranulation";"Pentose phosphate pathway" XP_018911268.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901967.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018907624.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_018913862.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018914418.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_018907327.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_018900557.1 6 Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_018913869.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018904116.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018897804.1 5 Reactome: R-HSA-73621;MetaCyc: PWY-7181;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.4;KEGG: 00983+2.4.2.4 "Pyrimidine catabolism";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_018910619.1 2 Reactome: R-HSA-114608;Reactome: R-HSA-2132295 "Platelet degranulation";"MHC class II antigen presentation" XP_018907162.1 7 MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466 "Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis" XP_018899955.1 3 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_018911247.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018908127.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018904818.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018917246.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018899041.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_018903509.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_018895582.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018907841.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_018913716.1 5 Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684 "Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Hedgehog 'on' state" XP_018909977.1 9 Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression" XP_018901942.1 10 MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13 "Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism" XP_018898979.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018901304.1 26 Reactome: R-HSA-3134973;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-2644606;Reactome: R-HSA-918233 "LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Attenuation phase";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF3-dependent IRF activation pathway" XP_018900349.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018904604.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_018912457.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_018899356.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018897388.1 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" XP_018912770.1 5 MetaCyc: PWY-2941;MetaCyc: PWY-2942;KEGG: 00261+1.17.1.8;KEGG: 00300+1.17.1.8;MetaCyc: PWY-5097 "L-lysine biosynthesis II";"L-lysine biosynthesis III";"Monobactam biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis VI" XP_018905452.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_018914298.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018900742.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_018909267.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018916216.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018914188.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-141444 "Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_018912870.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018913090.1 10 MetaCyc: PWY-5497;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-1722;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-5030 "Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III" XP_018904574.1 6 KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_018912177.1 3 KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B "Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates" XP_018902473.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018912399.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-212676;Reactome: R-HSA-9609736 "Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors" XP_018900488.1 24 Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Recycling pathway of L1";"Separation of Sister Chromatids";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"RHO GTPases Activate Formins";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018914491.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_018908171.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018903070.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949664 "Mitochondrial protein import";"Processing of SMDT1" XP_018907642.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_018917959.1 2 KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26 "Galactose metabolism";"Starch and sucrose metabolism" XP_018912924.1 11 Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167152 "RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat" XP_018909856.1 6 Reactome: R-HSA-400253;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "Circadian Clock";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018909573.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_018902630.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_018902740.1 6 KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17 "Ascorbate and aldarate metabolism";"Caprolactam degradation";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway" XP_018897720.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913638.1 4 KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-5737;MetaCyc: PWY-6922 "Arginine and proline metabolism";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis" XP_018906923.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_018913836.1 5 Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695 "RMTs methylate histone arginines";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling" XP_018912124.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" XP_018910552.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018907477.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_018910610.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_018917090.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018896437.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018897228.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_018899177.1 14 MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7417 "Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)" XP_018901148.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_018906331.1 7 KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-7790 "Pyrimidine metabolism";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"UMP biosynthesis II" XP_018902267.1 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" XP_018908686.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex" XP_018897511.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_018912685.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_018905510.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_018897266.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_018900060.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018917595.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_018900475.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_018901954.1 11 Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1989781 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression" XP_018905085.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_018911096.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018895913.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018906575.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018899635.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_018916645.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018898060.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_018903518.1 4 MetaCyc: PWY-5691;MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7849 "Urate conversion to allantoin I";"Urate conversion to allantoin II";"Purine metabolism";"Urate conversion to allantoin III" XP_018912657.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018905765.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_018902571.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018897666.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018918232.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_018917552.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018900992.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_018909608.1 5 Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-977225;Reactome: R-HSA-983168;Reactome: R-HSA-9646399 "Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Amyloid fiber formation";"Antigen processing: Ubiquitination & Proteasome degradation";"Aggrephagy" XP_018912700.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018901714.1 4 KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603 "Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine" XP_018916938.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018901305.1 26 Reactome: R-HSA-201722;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-1234158;Reactome: R-HSA-381340 "Formation of the beta-catenin:TCF transactivating complex";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation" XP_018912811.1 5 Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88 "Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism" XP_018916959.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_018901280.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_018912381.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018906697.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018900569.1 5 Reactome: R-HSA-9020702;Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-209560;Reactome: R-HSA-209543 "Interleukin-1 signaling";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes" XP_018913209.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-611105 "Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport" XP_018915403.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018902207.1 3 Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins" XP_018899408.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018912156.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018898372.1 3 MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403 "Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_018902922.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity" XP_018917494.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_018908572.1 37 Reactome: R-HSA-9639288;Reactome: R-HSA-159236;Reactome: R-HSA-2132295;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-204005;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-170822 "Amino acids regulate mTORC1";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"MHC class II antigen presentation";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"COPII-mediated vesicle transport";"tRNA processing in the nucleus";"snRNP Assembly";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_018914335.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_018903729.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_018916990.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_018917861.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_018918169.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018906492.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_018917877.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_018899888.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_018896432.1 3 Reactome: R-HSA-5689603;Reactome: R-HSA-2151201;Reactome: R-HSA-3214847 "UCH proteinases";"Transcriptional activation of mitochondrial biogenesis";"HATs acetylate histones" XP_018914998.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018896125.1 33 Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-141444 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_018918015.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018898740.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_018907990.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018912939.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" XP_018910266.1 5 KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;MetaCyc: PWY-7185;Reactome: R-HSA-499943;MetaCyc: PWY-7177 "Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II" XP_018913809.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018896833.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_018904543.1 7 Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-264870 "Interaction between L1 and Ankyrins";"Nephrin family interactions";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins" XP_018910371.1 16 Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-983168;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-167243 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Tat-mediated HIV elongation arrest and recovery" XP_018916699.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018901781.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_018911412.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_018909354.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018910553.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018911597.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018897469.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018903537.1 18 MetaCyc: PWY-8051;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4 "Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism" XP_018898680.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018908001.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_018902518.1 12 Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167246 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript" XP_018916208.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_018899459.1 23 Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-418592;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-428930;Reactome: R-HSA-6814122 "Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 1";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"G alpha (s) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Ca2+ pathway";"G-protein activation";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_018896629.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_018911867.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018905707.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018916728.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018897521.1 6 Reactome: R-HSA-5626467;Reactome: R-HSA-2173796;Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3769402 "RHO GTPases activate IQGAPs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Deactivation of the beta-catenin transactivating complex" XP_018910882.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_018901748.1 2 Reactome: R-HSA-114608;Reactome: R-HSA-2132295 "Platelet degranulation";"MHC class II antigen presentation" XP_018911061.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018898038.1 1 KEGG: 00565+3.1.1.47 "Ether lipid metabolism" XP_018907573.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_018907338.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018905143.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018901439.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018898593.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_018900212.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018913325.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_018906040.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018910446.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_018903933.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018917184.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018916147.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_018911996.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_018910340.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018902506.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex" XP_018900873.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_018906523.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_018896513.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Purine metabolism";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_018914000.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_018907160.1 27 Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854 "SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly" XP_018901699.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018897899.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_018904415.1 9 Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69183 "Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"G1/S-Specific Transcription";"Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand" XP_018915925.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_018909848.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018915727.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_018899266.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913115.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69205 "Cyclin E associated events during G1/S transition";"G0 and Early G1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription" XP_018901971.1 14 Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-69091 "Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching" XP_018896910.1 5 Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220 "Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism" XP_018906388.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6 "Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Peroxisomal protein import";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism" XP_018896600.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_018903172.1 8 Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_018897684.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018911186.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_018915713.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_018903057.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_018901023.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_018911714.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018900121.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718 "PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes" XP_018902450.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_018899829.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_018909266.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin" XP_018914101.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018908051.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018918050.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_018914058.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50 "HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation" XP_018910138.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_018910189.1 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685 "Glutathione metabolism";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species" XP_018910363.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_018896456.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018917358.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018911979.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_018900076.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018902027.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_018899604.1 33 Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379 "Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events" XP_018905291.1 16 MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-6886;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-7124;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622 "Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)" XP_018911116.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018903755.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_018901394.1 52 Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Neddylation";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"CLEC7A (Dectin-1) signaling" XP_018912184.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_018911093.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018908451.1 8 Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-6372;MetaCyc: PWY-4661;MetaCyc: PWY-2301 "Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Myo-inositol biosynthesis" XP_018910640.1 8 KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_018912459.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018906214.1 2 KEGG: 00040+5.3.1.5;KEGG: 00051+5.3.1.5 "Pentose and glucuronate interconversions";"Fructose and mannose metabolism" XP_018895618.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018906480.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_018904971.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_018913605.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018901271.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)" XP_018914794.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018903541.1 31 MetaCyc: PWY-8047;MetaCyc: PWY-5971;MetaCyc: PWY-6799;MetaCyc: PWY-5147;MetaCyc: PWY-5142;MetaCyc: PWY-5367;Reactome: R-HSA-2426168;MetaCyc: PWY-5994;MetaCyc: PWY-6282;MetaCyc: PWY-6519;MetaCyc: PWY-7858;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-4381;MetaCyc: PWY-7664;Reactome: R-HSA-163765;MetaCyc: PWY-5973;MetaCyc: PWY-8012;Reactome: R-HSA-9029558;MetaCyc: PWY-7746;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;Reactome: R-HSA-199220;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-5966-1;MetaCyc: PWY-7388;MetaCyc: PWY-5989 "Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis I (plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"Cis-vaccenate biosynthesis";"Mupirocin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mycobacterial sulfolipid biosynthesis";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"";"Pederin biosynthesis";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)" XP_018912376.1 7 Reactome: R-HSA-3108214;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052 "SUMOylation of DNA damage response and repair proteins";"Estrogen-dependent gene expression";"Meiotic synapsis";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion" XP_018915088.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" YP_086810.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_018900138.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_018907524.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_018897900.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_018907423.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090 "Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Collagen degradation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures" XP_018909365.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_018898035.1 5 MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22 "Stachyose degradation";"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_018898748.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_018912597.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_018898757.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_018898430.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018917508.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_018913206.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport" XP_018914493.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_018904871.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018897240.1 14 Reactome: R-HSA-2559582;Reactome: R-HSA-69656;Reactome: R-HSA-9617828;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-187577;Reactome: R-HSA-5625900;Reactome: R-HSA-69202;Reactome: R-HSA-2559586;Reactome: R-HSA-69563;Reactome: R-HSA-8849470;Reactome: R-HSA-69231;Reactome: R-HSA-6804116;Reactome: R-HSA-9634638 "Senescence-Associated Secretory Phenotype (SASP)";"Cyclin A:Cdk2-associated events at S phase entry";"FOXO-mediated transcription of cell cycle genes";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"SCF(Skp2)-mediated degradation of p27/p21";"RHO GTPases activate CIT";"Cyclin E associated events during G1/S transition";"DNA Damage/Telomere Stress Induced Senescence";"p53-Dependent G1 DNA Damage Response";"PTK6 Regulates Cell Cycle";"Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_018898968.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018912093.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018917915.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018901849.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-936440;Reactome: R-HSA-918233;Reactome: R-HSA-9013973 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7" XP_018916769.1 8 Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Signaling by Hippo";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_018912049.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_018910623.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167162 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape" XP_018897865.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018916888.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_018898772.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_018910264.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018912943.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018909447.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018898376.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018912660.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_018911075.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018904979.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018905015.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-5676590 "Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Degradation of AXIN";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling" XP_018913997.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_018917859.1 2 Reactome: R-HSA-191273;Reactome: R-HSA-2426168 "Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_018899780.1 4 Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874;Reactome: R-HSA-189483 "Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation I";"Heme degradation" XP_018907189.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018910342.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018902675.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_018910768.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018913124.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_018907339.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018908479.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018903891.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-191859 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"snRNP Assembly" XP_018910403.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018912944.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018901321.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_018902264.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis" XP_018905137.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation" XP_018898557.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_018915941.1 13 Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-2024096;Reactome: R-HSA-4341670;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695 "Sialic acid metabolism";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"MPS IV - Morquio syndrome B";"HS-GAG degradation";"Defective NEU1 causes sialidosis";"Other glycan degradation";"Sphingolipid metabolism";"Neutrophil degranulation" XP_018914714.1 7 MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane" XP_018902990.1 8 Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209 "Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation" XP_018906671.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway" XP_018905196.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_018908210.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_018903003.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_018899516.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018896809.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018908201.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_018905491.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_018895901.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018905195.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" YP_086812.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018895733.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_018896209.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766 "tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion" XP_018895971.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018911468.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_018905127.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018901140.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_018911336.1 12 KEGG: 00670+2.1.2.9;Reactome: R-HSA-73817;MetaCyc: PWY-6613;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.2;Reactome: R-HSA-196780;MetaCyc: PWY-6122;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6121;KEGG: 00230+6.3.3.1;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6277 "One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"One carbon pool by folate";"Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_018913617.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018904914.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_018906743.1 3 Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425 "Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1" XP_018896611.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018904568.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018898296.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018900882.1 4 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546;Reactome: R-HSA-8849175 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism" XP_018902672.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_018907977.1 6 Reactome: R-HSA-418597;Reactome: R-HSA-1250196;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-2029485 "G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"Role of phospholipids in phagocytosis" XP_018904762.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_018900640.1 29 Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-77075 "RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE" XP_018914222.1 13 MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_018909652.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_018909327.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_018917481.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_018917308.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018906737.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_018906096.1 7 Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;Reactome: R-HSA-8856828;Reactome: R-HSA-1855183;MetaCyc: PWY-6368 "Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Clathrin-mediated endocytosis";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation" XP_018896928.1 31 MetaCyc: PWY-7663;Reactome: R-HSA-75105;MetaCyc: PWY-7723;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-6519;MetaCyc: PWY-7858;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;MetaCyc: PWY-7746;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;Reactome: R-HSA-199220;MetaCyc: PWYG-321;MetaCyc: PWY-6113;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-5973;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWY-6282;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-5971;MetaCyc: PWY-5142;MetaCyc: PWY-5367;MetaCyc: PWY-6799;MetaCyc: PWY-5147 "Gondoate biosynthesis (anaerobic)";"Fatty acyl-CoA biosynthesis";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mycobacterial sulfolipid biosynthesis";"Biotin metabolism";"Pederin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Cis-vaccenate biosynthesis";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis I (plants)" XP_018908352.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018915063.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018909081.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends" XP_018911598.1 6 MetaCyc: PWY-7077;MetaCyc: PWY-7395;Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;MetaCyc: PWY-6906 "N-acetyl-D-galactosamine degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_018910263.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018902500.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_018912687.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_018902451.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_018907303.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295 "Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"MHC class II antigen presentation" XP_018897890.1 5 KEGG: 00030+4.1.2.4;Reactome: R-HSA-6798695;MetaCyc: PWY-7180;Reactome: R-HSA-71336;MetaCyc: PWY-8060 "Pentose phosphate pathway";"Neutrophil degranulation";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I" XP_018903186.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018901555.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974 "UCH proteinases";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Neddylation";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"ER-Phagosome pathway" XP_018901144.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_018904184.1 18 Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417 "Acyl chain remodelling of PE";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Synthesis of PA";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)" XP_018917364.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" XP_018909851.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018897779.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation" XP_018914959.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_018909084.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018911074.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018915426.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" XP_018895740.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_018915037.1 1 MetaCyc: PWY-6938 "NADH repair" XP_018905531.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_018904120.1 3 Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269 "Sialic acid metabolism";"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis" XP_018908531.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018906898.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018909593.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_018911153.1 14 Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426496 "Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs" XP_018909485.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_018902586.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes" XP_018899703.1 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" XP_018906474.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_018897343.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018900009.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018913221.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69091 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching" XP_018896297.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018900258.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_018899656.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018906444.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_018916906.1 3 MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17 "Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis" XP_018913300.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018895946.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018915215.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_018903991.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018914920.1 15 Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348 "Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex" XP_018902667.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_018900644.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_018899524.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018910557.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018916574.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018910346.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018900578.1 2 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_018909735.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_018895929.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_018909046.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018903201.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_018905257.1 5 Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253 "Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_018917739.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_018906447.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_018914272.1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-983168 "CLEC7A (Dectin-1) signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Neddylation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Degradation of DVL";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018900570.1 5 Reactome: R-HSA-209560;Reactome: R-HSA-205043;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-5205685 "NF-kB is activated and signals survival";"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"Pink/Parkin Mediated Mitophagy" XP_018909458.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins" YP_086802.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018912386.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018900889.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_018900518.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018908384.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_018908825.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_018898072.1 6 MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-446199 "Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Synthesis of Dolichyl-phosphate" XP_018904782.1 11 Reactome: R-HSA-5617472;Reactome: R-HSA-450341;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-2559582;Reactome: R-HSA-6796648;Reactome: R-HSA-5687128;Reactome: R-HSA-8862803;Reactome: R-HSA-2871796;Reactome: R-HSA-1912408;Reactome: R-HSA-8943724 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the AP-1 family of transcription factors";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"TP53 Regulates Transcription of DNA Repair Genes";"MAPK6/MAPK4 signaling";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FCERI mediated MAPK activation";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN gene transcription" XP_018917158.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018904010.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_018903598.1 8 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_018916844.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_018904975.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018906313.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER" XP_018908236.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage" XP_018914766.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_018917495.1 4 KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_018899582.1 6 MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-6983;Reactome: R-HSA-1474151 "Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_018904662.1 26 Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690 "Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Gap junction assembly";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Recycling pathway of L1";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"Kinesins";"RHO GTPases activate IQGAPs";"HCMV Early Events" XP_018904577.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_018901982.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_018905518.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018900120.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974 "UCH proteinases";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"ER-Phagosome pathway" XP_018904652.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018902792.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_018901987.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_018909359.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_018895751.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_018901697.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_018903307.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_018897862.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018915651.1 13 MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;Reactome: R-HSA-1362409;Reactome: R-HSA-1268020;Reactome: R-HSA-446205;MetaCyc: PWY-6992;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-882;MetaCyc: PWY-7586 "Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import";"Synthesis of GDP-mannose";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" XP_018914754.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_018906897.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018901234.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018898724.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_018911365.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_018916892.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes" XP_018914968.1 3 KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_018914045.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018903017.1 5 MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109 "Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis" XP_018899584.1 6 MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-5663 "Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I" XP_018918157.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_018900890.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_018908044.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_018914942.1 57 Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553 "Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs" XP_018897882.1 52 Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-5250924;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-76071;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-76061;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-73863 "FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination" XP_018916936.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018903275.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018903620.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_018898592.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_018903996.1 6 MetaCyc: PWY-7626;MetaCyc: PWY-6120;MetaCyc: PWY-3461;MetaCyc: PWY-3462;KEGG: 00400+5.4.99.5;MetaCyc: PWY-6627 "Bacilysin biosynthesis";"L-tyrosine biosynthesis III";"L-tyrosine biosynthesis II";"L-phenylalanine biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Salinosporamide A biosynthesis" XP_018899841.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_018904317.1 6 Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-5654693 "FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR1 signaling" XP_018896231.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_018910986.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_018914257.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018907884.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018905367.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018895900.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018901636.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_018902841.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_018915168.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018897025.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018917191.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018913451.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_018901094.1 10 MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8053 "Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II" XP_018918234.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_018909500.1 12 MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II" XP_018917695.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_018906054.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_018913378.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_018917950.1 9 KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation" XP_018909199.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_018917592.1 5 MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" XP_018917336.1 14 MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8051 "Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I" XP_018903254.1 19 Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480 "Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Chylomicron assembly";"Chylomicron clearance";"Chylomicron remodeling";"LDL remodeling";"Scavenging by Class A Receptors" XP_018902682.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion" XP_018904761.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018901570.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018912090.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_018903728.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_018898110.1 4 MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I" XP_018912670.1 6 MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-622 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis" XP_018917940.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018908436.1 14 MetaCyc: PWY-6936;MetaCyc: PWY-6309;Reactome: R-HSA-8964539;MetaCyc: PWY-2821;MetaCyc: PWY-801;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;Reactome: R-HSA-8964208;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240 "Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutamate and glutamine metabolism";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Phenylalanine metabolism";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Tryptophan catabolism" XP_018914123.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018910658.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018907057.1 9 Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-6142 "Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_018902767.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_018914526.1 8 MetaCyc: PWY-7733;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-5651;KEGG: 00380+3.5.1.9;MetaCyc: PWY-6309;MetaCyc: PWY-7717;MetaCyc: PWY-7765 "3-hydroxyquinaldate biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Quinoxaline-2-carboxylate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II" XP_018908714.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018901717.1 5 KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation" XP_018898920.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018911371.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018908154.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_018898064.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-75815 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of AXIN";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Neddylation";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D" XP_018898550.1 11 MetaCyc: PWY-7102;MetaCyc: PWY-7391;MetaCyc: PWY-6859;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-5123;MetaCyc: PWY-922;MetaCyc: PWY-7560;MetaCyc: PWY-6383;MetaCyc: PWY-6174 "Bisabolene biosynthesis (engineered)";"Isoprene biosynthesis II (engineered)";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway I";"Methylerythritol phosphate pathway II";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway II (archaea)" XP_018901469.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187 "Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress" XP_018903099.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_018904974.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018917806.1 13 MetaCyc: PWY-7857;MetaCyc: PWY-5108;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-7118;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1 "Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Propanoate metabolism";"Ethanol oxidation";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Methane metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes" XP_018904772.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_018904418.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018909221.1 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_018910094.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_018895624.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018898823.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018908007.1 2 Reactome: R-HSA-5627123;Reactome: R-HSA-8856828 "RHO GTPases activate PAKs";"Clathrin-mediated endocytosis" XP_018914832.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" XP_018917516.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_018903257.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018901164.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_018914913.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018905132.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018911046.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018895734.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_018895565.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018912669.1 6 MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism" XP_018917711.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_018896139.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018908482.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018916169.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018915095.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018899150.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_018907933.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_018898694.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_018899631.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_018906554.1 3 Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151 "eNOS activation";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_018918021.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018912382.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018896184.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)" XP_018915728.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_018905533.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_018917754.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_018898385.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018900003.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_018896425.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018917248.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018895938.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_018910436.1 5 MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis" XP_018902759.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_018911072.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018902705.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018912948.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018899363.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018900997.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_018903141.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018896043.1 4 Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Laminin interactions";"MET activates PTK2 signaling" XP_018916836.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_018904320.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018897142.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_018912072.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598 "Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis" XP_018902588.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018918009.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_018905357.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018905849.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018914767.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_018909893.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901292.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018917863.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018911624.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_018904011.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_018915443.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_018917230.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_018908570.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_018913251.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018906141.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018897139.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth" XP_018898805.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_018909067.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_018906638.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018913925.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_018903870.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_018896292.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_018896404.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018906595.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_018897775.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018900841.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_018912673.1 13 MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7220 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_018911941.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_018914490.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018906426.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018902194.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5972 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)" XP_018915606.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018910433.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018896927.1 31 MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-7858;Reactome: R-HSA-163765;MetaCyc: PWY-5973;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWYG-321;MetaCyc: PWY-6113;MetaCyc: PWY-8049;Reactome: R-HSA-199220;MetaCyc: PWY-7746;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-9029558;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-5367;MetaCyc: PWY-5142;Reactome: R-HSA-2426168;MetaCyc: PWY-6282;MetaCyc: PWY-5994 "Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression";"Cis-vaccenate biosynthesis";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"";"Superpathway of mycolate biosynthesis";"Pederin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Mycobacterial sulfolipid biosynthesis";"Biotin metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis (animals and fungi, cytoplasm)" XP_018902002.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018899133.1 11 Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-5663213;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973;Reactome: R-HSA-69231 "Factors involved in megakaryocyte development and platelet production";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"RHO GTPases Activate WASPs and WAVEs";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation";"Cyclin D associated events in G1" XP_018912902.1 19 Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825 "Chylomicron clearance";"Chylomicron assembly";"Chylomicron remodeling";"LDL remodeling";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"VLDL assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis" XP_018903395.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018896434.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018899031.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_018901582.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018907090.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018902028.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_018901423.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-611105 "Mitochondrial protein import";"Respiratory electron transport" XP_018899675.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_018900762.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018911544.1 8 MetaCyc: PWY-6444;MetaCyc: PWY-5883;KEGG: 00940+4.3.1.24;MetaCyc: PWY-1121;MetaCyc: PWY-5048;Reactome: R-HSA-70921;KEGG: 00360+4.3.1.24;MetaCyc: PWY-6457 "Benzoate biosynthesis II (CoA-independent, non-beta-oxidative)";"Ephedrine biosynthesis";"Phenylpropanoid biosynthesis";"Suberin monomers biosynthesis";"Rosmarinic acid biosynthesis I";"Histidine catabolism";"Phenylalanine metabolism";"Cinnamoyl-coa biosynthesis" XP_018915258.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_018901104.1 5 Reactome: R-HSA-8963693;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012 "Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_018911362.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_018916992.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018899026.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_018910767.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_018896382.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018896936.1 31 MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-5973;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-7664;Reactome: R-HSA-199220;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-7746;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-4381;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7858;MetaCyc: PWY-6519;Reactome: R-HSA-2426168;MetaCyc: PWY-6282;MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-5971;MetaCyc: PWY-8047 "Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Cis-vaccenate biosynthesis";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mycobacterial sulfolipid biosynthesis";"Biotin metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis" XP_018915759.1 3 KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691 "Caffeine metabolism";"Purine metabolism";"Urate conversion to allantoin I" XP_018895681.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018898632.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_018908713.1 4 Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;MetaCyc: PWY-6517 "Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"N-acetylglucosamine degradation II" XP_018913863.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018896471.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway" XP_018903231.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018914819.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events" XP_018902118.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_018902036.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018912035.1 11 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-9614657;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"FOXO-mediated transcription of cell death genes";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_018896087.1 10 KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;Reactome: R-HSA-1855191;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6362 "Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_018910611.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_018905359.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_018917047.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018901022.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_018898349.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018897078.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018911723.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_018914607.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_018898298.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018915643.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_018901043.1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-5628897 "Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes" XP_018910145.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018900919.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018914539.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_018899871.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_018902197.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis" XP_018914012.1 5 Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131 "Collagen degradation";"MHC class II antigen presentation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR" XP_018912668.1 6 MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism" XP_018906545.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_018915626.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018898859.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_018908537.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018907047.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416476 "Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events" XP_018895737.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_018897682.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018911271.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018905261.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018916997.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_018911395.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_018903014.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_018904999.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018898315.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_018913649.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018896918.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_018897164.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_018897892.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_018900931.1 12 Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-982772;Reactome: R-HSA-5362798;Reactome: R-HSA-75893 "Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Growth hormone receptor signaling";"Release of Hh-Np from the secreting cell";"TNF signaling" XP_018914459.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_018905468.1 11 KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_018908870.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_018903925.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018914709.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_018897631.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018901850.1 5 Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-936440 "TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling" XP_018896401.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018917182.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018896885.1 5 Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220 "Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism" XP_018912091.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_018902712.1 18 Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_018918076.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018913865.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018904090.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018918098.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018914487.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018903561.1 17 KEGG: 00254+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-3371599;MetaCyc: PWY-6722;MetaCyc: PWY-5744;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743 "Aflatoxin biosynthesis";"Jadomycin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Candicidin biosynthesis";"Glyoxylate assimilation";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"Fatty acid biosynthesis";"Pyruvate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle" XP_018906471.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018907820.1 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" XP_018906695.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_018911246.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018906714.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018906328.1 6 Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368 "Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation" XP_018898884.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018906633.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018899093.1 4 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300 "DNA methylation";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA" XP_018901709.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018909800.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018909316.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018906209.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_018898042.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813 "Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"ER-Phagosome pathway";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids" XP_018917526.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_018917083.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_018907991.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_018914821.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_018898326.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_018916594.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018902041.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events" XP_018909117.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_018911225.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018897977.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018908216.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_018903007.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_018915027.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_018907891.1 10 Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;Reactome: R-HSA-437239;Reactome: R-HSA-442742;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "RSK activation";"Human cytomegalovirus infection";"Recycling pathway of L1";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_018905709.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_018909003.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_018906134.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018913944.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018904171.1 20 MetaCyc: PWY-7338;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7007;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-5136;MetaCyc: PWY-6837 "10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" XP_018902340.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018900946.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018917937.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_018902014.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_018902629.1 10 Reactome: R-HSA-427413;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017 "NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_018915730.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_018916013.1 3 Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144 "Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_018906334.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_018896426.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018903878.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018908274.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018917960.1 2 KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26 "Starch and sucrose metabolism";"Galactose metabolism" XP_018914347.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_018914382.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_018898287.1 5 Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131 "Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"Collagen degradation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR" XP_018912651.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018914818.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040 "Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"PKA activation";"Purine metabolism";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_018911099.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018914466.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018909189.1 5 Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796 "Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"FCERI mediated MAPK activation" XP_018896711.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_018906006.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018904439.1 2 Reactome: R-HSA-114608;Reactome: R-HSA-2132295 "Platelet degranulation";"MHC class II antigen presentation" XP_018907209.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901166.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_018916891.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_018902477.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_018916302.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_018899727.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018913369.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_018915932.1 3 Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_018910170.1 6 Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;MetaCyc: PWY-6898 "Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III" XP_018900794.1 5 MetaCyc: PWY-3781;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-7279 "Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)" XP_018914914.1 15 Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402 "S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex" XP_018900817.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018918202.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018908203.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_018907821.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_018901089.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018914592.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_018903012.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_018904757.1 13 Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-416993;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900 "MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Trafficking of GluR2-containing AMPA receptors";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4" XP_018906809.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_018905069.1 13 Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-419037;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-186797;Reactome: R-HSA-3000157;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "ECM proteoglycans";"Collagen chain trimerization";"NCAM1 interactions";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Signaling by PDGF";"Laminin interactions";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_018900469.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_018912187.1 5 Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105 "ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis" XP_018914361.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018908606.1 6 KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23 "Glycosaminoglycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_018896849.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018912966.1 3 KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456 "Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid" XP_018910796.1 3 Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins" XP_018901123.1 4 KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_018911216.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_018909115.1 4 KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_018895779.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018902303.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_018905116.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018901293.1 4 KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)" XP_018904707.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5218920 "Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability" XP_018900259.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018906469.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018906620.1 6 MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17 "L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Sorbitol biosynthesis II";"Pentose phosphate pathway" XP_018900351.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_018910916.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018897791.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Neutrophil degranulation";"Amino acids regulate mTORC1" XP_018917879.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_018917858.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_018907932.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018906963.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_018896076.1 10 MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-8001 "Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_018902823.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy" XP_018899038.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_018903382.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018901185.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018914655.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018901637.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_018917065.1 10 KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2 "Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Cyanoamino acid metabolism" XP_018905627.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_018898792.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_018913395.1 5 Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex" XP_018909963.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_018901698.1 4 Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_018899005.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131 "Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Collagen degradation";"Trafficking and processing of endosomal TLR" XP_018904367.1 5 Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5689901 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs" XP_018913765.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018911174.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018902561.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364 "Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_018913214.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018899986.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018897774.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018896774.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105 "Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis" XP_018912835.1 7 MetaCyc: PWY-5941;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;Reactome: R-HSA-6798695 "Glycogen degradation II";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Neutrophil degranulation" XP_018908473.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_018902385.1 5 Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614 "Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage" XP_018903235.1 5 Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-6811555;Reactome: R-HSA-5668599;Reactome: R-HSA-6804756 "ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases";"Regulation of TP53 Activity through Phosphorylation" XP_018914246.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_018908548.1 3 Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096 "MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation" XP_018899882.1 7 Reactome: R-HSA-2173795;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-5696395 "Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER" XP_018916597.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018917177.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018911855.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_018914303.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_018908074.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_018903986.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018899040.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_018909437.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018913353.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018912664.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_018900804.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7 "Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis" XP_018908631.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018898169.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_018902709.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018915505.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_018913853.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018895731.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_018900705.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018905129.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018899366.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_018897881.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Selenocompound metabolism" XP_018895610.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018900775.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" XP_018909347.1 20 MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337 "9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)" XP_018902507.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_018905813.1 4 KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes" XP_018901357.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_018911976.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_018907840.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_018902688.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018911129.1 13 MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"CS/DS degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis" XP_018903937.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_018898929.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662 "Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism" XP_018913933.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" XP_018899426.1 5 Reactome: R-HSA-1237112;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-111458 "Methionine salvage pathway";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome" XP_018903203.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system" XP_018917017.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_018913720.1 5 Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5620922 "Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Hedgehog 'on' state";"Activation of SMO";"BBSome-mediated cargo-targeting to cilium" XP_018901603.1 6 Reactome: R-HSA-196780;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15 "Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism" XP_018904883.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018899774.1 4 Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483;MetaCyc: PWY-5874 "Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation";"Heme degradation I" XP_018913055.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_018902131.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018904306.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018902674.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_018905128.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018909400.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_018898818.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_018898182.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018906038.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018900067.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_018899226.1 44 Reactome: R-HSA-445144;Reactome: R-HSA-2559580;Reactome: R-HSA-198753;Reactome: R-HSA-5654733;Reactome: R-HSA-2871796;Reactome: R-HSA-2559585;Reactome: R-HSA-6802952;Reactome: R-HSA-9635465;Reactome: R-HSA-5675221;Reactome: R-HSA-375165;KEGG: 04150+2.7.11.24;Reactome: R-HSA-6811558;Reactome: R-HSA-2559582;Reactome: R-HSA-170968;Reactome: R-HSA-8943724;Reactome: R-HSA-6802946;Reactome: R-HSA-5674499;Reactome: R-HSA-9649948;Reactome: R-HSA-879415;Reactome: R-HSA-1295596;Reactome: R-HSA-5654726;Reactome: R-HSA-5654732;Reactome: R-HSA-5674135;Reactome: R-HSA-456926;Reactome: R-HSA-5673001;Reactome: R-HSA-982772;Reactome: R-HSA-450341;Reactome: R-HSA-74749;Reactome: R-HSA-8939211;Reactome: R-HSA-2029482;Reactome: R-HSA-9634638;Reactome: R-HSA-202670;Reactome: R-HSA-5654727;Reactome: R-HSA-112409;Reactome: R-HSA-6802948;Reactome: R-HSA-162658;Reactome: R-HSA-881907;Reactome: R-HSA-8940973;Reactome: R-HSA-444257;Reactome: R-HSA-3371453;Reactome: R-HSA-5668599;Reactome: R-HSA-9627069;Reactome: R-HSA-6802955;Reactome: R-HSA-5663213 "Signal transduction by L1";"Oxidative Stress Induced Senescence";"ERK/MAPK targets";"Negative regulation of FGFR4 signaling";"FCERI mediated MAPK activation";"Oncogene Induced Senescence";"Signaling by BRAF and RAF fusions";"Suppression of apoptosis";"Negative regulation of MAPK pathway";"NCAM signaling for neurite out-growth";"mTOR signaling pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Frs2-mediated activation";"Regulation of PTEN gene transcription";"Signaling by moderate kinase activity BRAF mutants";"Negative feedback regulation of MAPK pathway";"Signaling downstream of RAS mutants";"Advanced glycosylation endproduct receptor signaling";"Spry regulation of FGF signaling";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR3 signaling";"MAP2K and MAPK activation";"Thrombin signalling through proteinase activated receptors (PARs)";"RAF/MAP kinase cascade";"Growth hormone receptor signaling";"Activation of the AP-1 family of transcription factors";"Signal attenuation";"ESR-mediated signaling";"Regulation of actin dynamics for phagocytic cup formation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"ERKs are inactivated";"Negative regulation of FGFR2 signaling";"RAF-independent MAPK1/3 activation";"Signaling by high-kinase activity BRAF mutants";"Golgi Cisternae Pericentriolar Stack Reorganization";"Gastrin-CREB signalling pathway via PKC and MAPK";"RUNX2 regulates osteoblast differentiation";"RSK activation";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate NADPH Oxidases";"Regulation of the apoptosome activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RHO GTPases Activate WASPs and WAVEs" XP_018895988.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_018900611.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018906955.1 2 Reactome: R-HSA-167827;Reactome: R-HSA-167826 "The proton buffering model";"The fatty acid cycling model" XP_018903463.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_018900869.1 3 Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_018901675.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018898049.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_018917415.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_018912506.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_018916355.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018897066.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018904891.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_018909143.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619 "Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis" XP_018896509.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_018907411.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018901532.1 26 Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-389960;Reactome: R-HSA-2467813 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids" XP_018906496.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_018909595.1 8 KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_018909194.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription" XP_018916592.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018915631.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Translation initiation complex formation" XP_018909512.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018915968.1 8 Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4" XP_018914581.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" XP_018913838.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_018896719.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_018912298.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_018902196.1 14 MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7724 "(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_018895712.1 9 Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-8086;Reactome: R-HSA-3371599;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1 "Biotin transport and metabolism";"Pyruvate metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" XP_018910650.1 15 Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-2173796;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167287 "RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery" XP_018916136.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_018910184.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_018912860.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018910620.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557 "Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis" XP_018905339.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_018911299.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_018917750.1 27 Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_018914333.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_018912180.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_018918121.1 34 Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-69273;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-69656;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-8939236;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167162 "RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A:Cdk2-associated events at S phase entry";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"mRNA Capping";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape" XP_018898965.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018896890.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616 "Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication" XP_018900594.1 16 Reactome: R-HSA-1266695;Reactome: R-HSA-2219530;Reactome: R-HSA-912631;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-194840;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-114604;Reactome: R-HSA-1660499 "Interleukin-7 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of signaling by CBL";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Rho GTPase cycle";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane" XP_018916907.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_018909350.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_018900466.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-983170 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_018912297.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_018899106.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018898845.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018917262.1 9 Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827 "Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_018903400.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018915440.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_018901539.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_018908169.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018901303.1 26 Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-8866907;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-201722;Reactome: R-HSA-2644606;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-918233 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Attenuation phase";"Circadian Clock";"TRAF3-dependent IRF activation pathway" XP_018914726.1 3 Reactome: R-HSA-5694530;Reactome: R-HSA-948021;Reactome: R-HSA-204005 "Cargo concentration in the ER";"Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport" XP_018896578.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_018916015.1 3 KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway" XP_018909038.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_018910554.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018910426.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018917908.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018913916.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_018908738.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018907028.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018901458.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_018899883.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_018906392.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018905194.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018902016.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_018912007.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_018904895.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018909590.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_018909301.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_018907602.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018899707.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018905784.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_018900743.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_018906441.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism" XP_018907294.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295 "Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"MHC class II antigen presentation" XP_018906138.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018917881.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_018917028.1 2 Reactome: R-HSA-5083628;Reactome: R-HSA-5173105 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation" XP_018912362.1 182 Reactome: R-HSA-6804760;Reactome: R-HSA-2173796;Reactome: R-HSA-9033241;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-2408557;Reactome: R-HSA-4641258;Reactome: R-HSA-4641263;Reactome: R-HSA-6782135;Reactome: R-HSA-5205685;Reactome: R-HSA-5607761;Reactome: R-HSA-5696394;Reactome: R-HSA-5357956;Reactome: R-HSA-977225;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-192823;Reactome: R-HSA-69481;Reactome: R-HSA-975144;Reactome: R-HSA-5676590;Reactome: R-HSA-6804756;Reactome: R-HSA-5654732;Reactome: R-HSA-9645460;Reactome: R-HSA-5654726;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-72764;Reactome: R-HSA-5656121;Reactome: R-HSA-202424;Reactome: R-HSA-8863795;Reactome: R-HSA-8876493;Reactome: R-HSA-2894862;Reactome: R-HSA-936964;Reactome: R-HSA-5678895;Reactome: R-HSA-937041;Reactome: R-HSA-975957;Reactome: R-HSA-400253;Reactome: R-HSA-156902;Reactome: R-HSA-917937;Reactome: R-HSA-5610780;Reactome: R-HSA-8856825;Reactome: R-HSA-975956;Reactome: R-HSA-174084;Reactome: R-HSA-162588;Reactome: R-HSA-8866654;Reactome: R-HSA-110314;Reactome: R-HSA-2979096;Reactome: R-HSA-5689877;Reactome: R-HSA-9613829;Reactome: R-HSA-72702;Reactome: R-HSA-5684264;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-5675482;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-445989;Reactome: R-HSA-5689896;Reactome: R-HSA-5358346;Reactome: R-HSA-2565942;Reactome: R-HSA-901032;Reactome: R-HSA-68949;Reactome: R-HSA-209543;Reactome: R-HSA-3785653;Reactome: R-HSA-1253288;Reactome: R-HSA-8948747;Reactome: R-HSA-72706;Reactome: R-HSA-211733;Reactome: R-HSA-69231;Reactome: R-HSA-110312;Reactome: R-HSA-9014325;Reactome: R-HSA-5357905;Reactome: R-HSA-937039;Reactome: R-HSA-209560;Reactome: R-HSA-8866652;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-2122948;Reactome: R-HSA-6807004;Reactome: R-HSA-5654727;Reactome: R-HSA-917729;Reactome: R-HSA-8939902;Reactome: R-HSA-174048;Reactome: R-HSA-382556;Reactome: R-HSA-9615710;Reactome: R-HSA-205043;Reactome: R-HSA-8856828;Reactome: R-HSA-180585;Reactome: R-HSA-156827;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-168927;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-5689901;Reactome: R-HSA-168638;Reactome: R-HSA-8849469;Reactome: R-HSA-3134975;Reactome: R-HSA-9604323;Reactome: R-HSA-2691232;Reactome: R-HSA-110320;Reactome: R-HSA-1358803;Reactome: R-HSA-72695;Reactome: R-HSA-450302;Reactome: R-HSA-2122947;Reactome: R-HSA-5675221;Reactome: R-HSA-69601;Reactome: R-HSA-5693565;Reactome: R-HSA-9013973;Reactome: R-HSA-175474;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-2644606;Reactome: R-HSA-9637628;Reactome: R-HSA-1236382;Reactome: R-HSA-2559582;Reactome: R-HSA-9636383;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-201681;Reactome: R-HSA-2173791;Reactome: R-HSA-5610785;Reactome: R-HSA-5696397;Reactome: R-HSA-975110;Reactome: R-HSA-975163;Reactome: R-HSA-2173788;Reactome: R-HSA-6781823;Reactome: R-HSA-450321;Reactome: R-HSA-1799339;Reactome: R-HSA-5656169;Reactome: R-HSA-72689;Reactome: R-HSA-5632684;Reactome: R-HSA-5696400;Reactome: R-HSA-9013507;Reactome: R-HSA-5654733;Reactome: R-HSA-6791226;Reactome: R-HSA-532668;Reactome: R-HSA-912631;Reactome: R-HSA-2173795;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-6781827;Reactome: R-HSA-179409;Reactome: R-HSA-349425;Reactome: R-HSA-174490;Reactome: R-HSA-72649;Reactome: R-HSA-5610783;Reactome: R-HSA-69541;Reactome: R-HSA-6783310;Reactome: R-HSA-1295596;Reactome: R-HSA-3769402;Reactome: R-HSA-450408;Reactome: R-HSA-5696395;Reactome: R-HSA-2672351;Reactome: R-HSA-168928;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-6804757;Reactome: R-HSA-3322077;Reactome: R-HSA-9633012;Reactome: R-HSA-8941858;Reactome: R-HSA-1169408;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-9646399;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-8852276;Reactome: R-HSA-5655862;Reactome: R-HSA-182971;Reactome: R-HSA-936440;Reactome: R-HSA-8875360 "Regulation of TP53 Activity through Methylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Peroxisomal protein import";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"Selenocysteine synthesis";"Degradation of DVL";"Regulation of FZD by ubiquitination";"Dual incision in TC-NER";"Pink/Parkin Mediated Mitophagy";"Dectin-1 mediated noncanonical NF-kB signaling";"DNA Damage Recognition in GG-NER";"TNFR1-induced NFkappaB signaling pathway";"Amyloid fiber formation";"Neddylation";"FCERI mediated NF-kB activation";"Viral mRNA Translation";"G2/M Checkpoints";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NIK-->noncanonical NF-kB signaling";"Regulation of TP53 Activity through Phosphorylation";"Negative regulation of FGFR3 signaling";"Alpha-protein kinase 1 signaling pathway";"Negative regulation of FGFR1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Eukaryotic Translation Termination";"Translesion synthesis by POLI";"Downstream TCR signaling";"Downregulation of ERBB2 signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Defective CFTR causes cystic fibrosis";"IKK complex recruitment mediated by RIP1";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Circadian Clock";"Peptide chain elongation";"Iron uptake and transport";"Degradation of GLI1 by the proteasome";"Cargo recognition for clathrin-mediated endocytosis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Budding and maturation of HIV virion";"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Josephin domain DUBs";"Chaperone Mediated Autophagy";"Ribosomal scanning and start codon recognition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of necroptotic cell death";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Ovarian tumor domain proteases";"Hedgehog ligand biogenesis";"Regulation of PLK1 Activity at G2/M Transition";"ER Quality Control Compartment (ERQC)";"Orc1 removal from chromatin";"p75NTR recruits signalling complexes";"Myoclonic epilepsy of Lafora";"Downregulation of ERBB4 signaling";"Regulation of PTEN localization";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cyclin D associated events in G1";"Translesion synthesis by REV1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of TNFR1 signaling";"IRAK1 recruits IKK complex";"NF-kB is activated and signals survival";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Activated NOTCH1 Transmits Signal to the Nucleus";"Negative regulation of MET activity";"Negative regulation of FGFR2 signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Cyclin B";"ABC-family proteins mediated transport";"Late endosomal microautophagy";"NRIF signals cell death from the nucleus";"Clathrin-mediated endocytosis";"Vif-mediated degradation of APOBEC3G";"L13a-mediated translational silencing of Ceruloplasmin expression";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"TICAM1, RIP1-mediated IKK complex recruitment";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Metalloprotease DUBs";"NOD1/2 Signaling Pathway";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of innate immune responses to cytosolic DNA";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Translesion Synthesis by POLH";"Downregulation of ERBB2:ERBB3 signaling";"Formation of the ternary complex, and subsequently, the 43S complex";"activated TAK1 mediates p38 MAPK activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulation of MAPK pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TICAM1-dependent activation of IRF3/IRF7";"Assembly Of The HIV Virion";"Separation of Sister Chromatids";"Degradation of AXIN";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Modulation by Mtb of host immune system";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Senescence-Associated Secretory Phenotype (SASP)";"Prevention of phagosomal-lysosomal fusion";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"TCF dependent signaling in response to WNT";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"GLI3 is processed to GLI3R by the proteasome";"Gap-filling DNA repair synthesis and ligation in GG-NER";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downregulation of TGF-beta receptor signaling";"Formation of TC-NER Pre-Incision Complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"SRP-dependent cotranslational protein targeting to membrane";"Termination of translesion DNA synthesis";"Formation of a pool of free 40S subunits";"Hedgehog 'on' state";"Dual Incision in GG-NER";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of FGFR4 signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of signaling by CBL";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of the E3 ubiquitin ligase COP1";"Membrane binding and targetting of GAG proteins";"Translation initiation complex formation";"Degradation of GLI2 by the proteasome";"Stabilization of p53";"Fanconi Anemia Pathway";"Spry regulation of FGF signaling";"Deactivation of the beta-catenin transactivating complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Formation of Incision Complex in GG-NER";"Stimuli-sensing channels";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Regulation of TP53 Degradation";"Glycogen synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of RUNX3 expression and activity";"ISG15 antiviral mechanism";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Aggrephagy";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translesion synthesis by POLK";"EGFR downregulation";"Negative regulators of DDX58/IFIH1 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_018898981.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_018905239.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018901754.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018898363.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_018911154.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8943723 "TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation" XP_018907885.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018916384.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_018907509.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_018914962.1 4 Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018910089.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_018905311.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_018905227.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_018896487.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_018905858.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018896172.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_018900749.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018908032.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_018917161.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018904259.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_018897658.1 4 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" XP_018904524.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_018902669.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_018913890.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018911515.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_018908260.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018906662.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_018915580.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_018910648.1 15 Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-176034;Reactome: R-HSA-75955;Reactome: R-HSA-9018519 "RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression" XP_018901762.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018911313.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_018900514.1 7 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00330+2.5.1.22 "Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism" XP_018908547.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018896439.1 13 MetaCyc: PWY-7821;KEGG: 00230+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00230+3.6.1.66;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;KEGG: 00770+3.6.1.9 "Tunicamycin biosynthesis";"Purine metabolism";"Purine catabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Pantothenate and CoA biosynthesis" XP_018910213.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018900334.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_018910592.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_018904889.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018895736.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_018895879.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018914273.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_018905474.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018914297.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018904967.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_018897842.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018896637.1 5 MetaCyc: PWY-7918;MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954;Reactome: R-HSA-532668 "Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_018911372.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018914424.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018915779.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_018906144.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018909360.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_018917284.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_018898112.1 5 KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305 "Glycosaminoglycan degradation";"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D" XP_018912021.1 4 KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_018916629.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018902686.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_018911081.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_018914411.1 6 KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530 "Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Sorbitol biosynthesis II" XP_018907085.1 31 MetaCyc: PWY-7723;MetaCyc: PWY-7663;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-7858;MetaCyc: PWY-5973;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWYG-321;MetaCyc: PWY-8049;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-7746;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;MetaCyc: PWY-6282;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-5367;MetaCyc: PWY-5142 "Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Cis-vaccenate biosynthesis";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"";"Pederin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Biotin metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway" XP_018897628.1 4 Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" XP_018907925.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018914785.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018901605.1 6 MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_018901840.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I" XP_018896497.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_018914571.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_018900973.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018917058.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_018904911.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_018911373.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_018917547.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_018898507.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018910542.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018914918.1 15 Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348 "Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex" XP_018907437.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_018904599.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018914300.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_018906514.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_018902481.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018913888.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018901448.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_018917820.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs" XP_018916320.1 10 Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751 "WNT mediated activation of DVL";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Synthesis of PC";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity" XP_018900527.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-191859 "tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly" XP_018898165.1 2 MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_018901248.1 19 MetaCyc: PWY-7205;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7224;Reactome: R-HSA-380270;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;Reactome: R-HSA-380320;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7176 "CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of NuMA to mitotic centrosomes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis" XP_018896937.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018909936.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_018914158.1 6 MetaCyc: PWY-4381;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5789;Reactome: R-HSA-196780 "Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism" XP_018903009.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_018899948.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" XP_018916781.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_018905191.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018911994.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_018895685.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018897645.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018918117.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_018899146.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_018910428.1 6 MetaCyc: PWY-5514;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6906 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_018914957.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_018903626.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-211945;Reactome: R-HSA-8937144 "PPARA activates gene expression";"Xenobiotics";"Endogenous sterols";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling" XP_018902265.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis" XP_018901804.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_018916933.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018904562.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018910188.1 3 Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Glutathione metabolism" XP_018911312.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_018915396.1 42 Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-73728;Reactome: R-HSA-5334118;Reactome: R-HSA-3214847;Reactome: R-HSA-427359;Reactome: R-HSA-4551638;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-5617472;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-427389;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-3214815;Reactome: R-HSA-5693565;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-5625886;Reactome: R-HSA-3214841;Reactome: R-HSA-9616222;Reactome: R-HSA-3214858;Reactome: R-HSA-110329;Reactome: R-HSA-9609690;Reactome: R-HSA-977225;Reactome: R-HSA-69473;Reactome: R-HSA-212300;Reactome: R-HSA-171306;Reactome: R-HSA-2559582;Reactome: R-HSA-427413;Reactome: R-HSA-5578749 "HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Opening";"DNA methylation";"HATs acetylate histones";"SIRT1 negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDACs deacetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PKMTs methylate histone lysines";"Transcriptional regulation of granulopoiesis";"RMTs methylate histone arginines";"Cleavage of the damaged pyrimidine";"HCMV Early Events";"Amyloid fiber formation";"G2/M DNA damage checkpoint";"PRC2 methylates histones and DNA";"Packaging Of Telomere Ends";"Senescence-Associated Secretory Phenotype (SASP)";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs" XP_018900028.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018917070.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_018914129.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-5689880;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_018906698.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018902549.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018896940.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018903123.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_018913774.1 8 Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652 "Regulation of PTEN localization";"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_018915716.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_018905306.1 5 KEGG: 00240+2.7.1.21;KEGG: 00983+2.7.1.21;MetaCyc: PWY-7199;Reactome: R-HSA-73614;Reactome: R-HSA-69205 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine salvage";"G1/S-Specific Transcription" XP_018906688.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_018902977.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_018913779.1 1 Reactome: R-HSA-419771 "Opsins" XP_018914654.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018904009.1 8 Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556 "Ion channel transport";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes" XP_018902523.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_018905131.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018913119.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_018917073.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation" XP_018904087.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_018907258.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_018897131.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_018898409.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018897265.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_018911172.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018903294.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018899097.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018916827.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018917214.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018903313.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018899697.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018914242.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_018903198.1 6 MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_018896252.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6798695;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_018903766.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_018897943.1 11 Reactome: R-HSA-1963642;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-8847993 "PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"ERBB2 Activates PTK6 Signaling" XP_018899704.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018901299.1 5 MetaCyc: PWY-7176;MetaCyc: PWY-7185;Reactome: R-HSA-499943;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2 "UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism" XP_018902522.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" YP_086807.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018910173.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018908926.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018909338.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018907418.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_018916490.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018907449.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601 "Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_018911457.1 3 Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395 "Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER" XP_018910905.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_018906174.1 17 Reactome: R-HSA-174414;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-174417 "Processive synthesis on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis" XP_018910918.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018905394.1 3 MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78 "3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_018900164.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018917989.1 7 MetaCyc: PWY-5514;KEGG: 00030+3.1.1.31;Reactome: R-HSA-71336;KEGG: 00520+3.5.99.6;MetaCyc: PWY-8004;MetaCyc: PWY-6855;MetaCyc: PWY-6906 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"Chitin derivatives degradation" XP_018897938.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_018902781.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_018901447.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_018912330.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_018903710.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211945;Reactome: R-HSA-211976;Reactome: R-HSA-211981 "PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds";"Endogenous sterols";"Xenobiotics" XP_018917157.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018914880.1 13 MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_018898651.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_018903568.1 17 KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5744;MetaCyc: PWY-6722;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-5789 "Pyruvate metabolism";"Carnitine metabolism";"Fatty acid biosynthesis";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate assimilation";"Candicidin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Aflatoxin biosynthesis";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_018898578.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018906442.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_018916922.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;MetaCyc: PWY-7221 "Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis" XP_018913847.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018904552.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_018912449.1 56 Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-68949 "Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Degradation of DVL";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Orc1 removal from chromatin" XP_018899541.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_018910206.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_018913447.1 13 MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_018899594.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria" XP_018905155.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_018896767.1 5 Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105 "ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis" XP_018903082.1 17 Reactome: R-HSA-174417;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-174414;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-174411 "Telomere C-strand (Lagging Strand) Synthesis";"Dual incision in TC-NER";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere" XP_018898902.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_018913097.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_018901355.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_018909508.1 3 MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117 "Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I" XP_018909946.1 5 MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2 "L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism" XP_018896011.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_018897413.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398 "Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway" XP_018917216.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_018902636.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_018913653.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018906077.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_018899782.1 7 Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-5578749 "Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs" XP_018901070.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018912225.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_018899636.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_018902752.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_018913630.1 4 Reactome: R-HSA-70688;MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2 "Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_018907911.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_018904413.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018907864.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis" XP_018909103.1 13 MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7182;MetaCyc: PWY-7659;MetaCyc: PWY-7721 "(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Methyl phomopsenoate biosynthesis" XP_018910778.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits" XP_018913024.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_018907969.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_018896831.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_018899476.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_018914594.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_018896413.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018896468.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378 "G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling" XP_018909572.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_018909125.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704 "Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade" XP_018915483.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018905881.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018897376.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_018898022.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018899781.1 4 MetaCyc: PWY-5874;Reactome: R-HSA-189483;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18 "Heme degradation I";"Heme degradation";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism" XP_018903990.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018908228.1 12 Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-210744 "Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_018900650.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018908355.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_018914822.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-164378 "G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"PKA activation in glucagon signalling" XP_018908282.1 5 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_018905204.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_018916595.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018911103.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018907652.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_018897838.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_018902025.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018898047.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_018902253.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656 "Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling" XP_018899147.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_018917594.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_018901162.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_018917362.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018900932.1 12 Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-982772;Reactome: R-HSA-2660826;Reactome: R-HSA-75893;Reactome: R-HSA-5362798;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-177929 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"TNF signaling";"Release of Hh-Np from the secreting cell";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR" XP_018907966.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018900750.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018899859.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_018897089.1 19 Reactome: R-HSA-8964038;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-432142 "LDL clearance";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Post-translational protein phosphorylation";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"LDL remodeling";"Chylomicron remodeling";"Chylomicron assembly";"Chylomicron clearance";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL" XP_018900686.1 16 Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-164939;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-8964038 "WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Formation of annular gap junctions";"Gap junction degradation";"Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"LDL clearance" XP_018897646.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018907475.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_018900129.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018907045.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-399997 "G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion" XP_018917554.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_018908238.1 4 MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_018895686.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018899051.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_018897615.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018917458.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_018897753.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_018902258.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656 "TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling" XP_018906571.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018900696.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_018899967.1 9 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_018910447.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_018906930.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018917089.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018899752.1 5 MetaCyc: PWY-6892;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891 "Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)" XP_018896423.1 57 Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-174184 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Neddylation";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_018900503.1 18 Reactome: R-HSA-5362517;MetaCyc: PWY-5046;KEGG: 00260+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-71403;Reactome: R-HSA-70268;Reactome: R-HSA-71064;Reactome: R-HSA-389661;Reactome: R-HSA-70895;MetaCyc: PWY-5084;Reactome: R-HSA-204174;KEGG: 00310+1.8.1.4;KEGG: 00020+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00010+1.8.1.4;KEGG: 00620+1.8.1.4;KEGG: 00380+1.8.1.4 "Signaling by Retinoic Acid";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycine, serine and threonine metabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Regulation of pyruvate dehydrogenase (PDH) complex";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Tryptophan metabolism" XP_018897898.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018895924.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018911546.1 8 MetaCyc: PWY-6444;MetaCyc: PWY-1121;KEGG: 00940+4.3.1.24;MetaCyc: PWY-5883;MetaCyc: PWY-5048;Reactome: R-HSA-70921;MetaCyc: PWY-6457;KEGG: 00360+4.3.1.24 "Benzoate biosynthesis II (CoA-independent, non-beta-oxidative)";"Suberin monomers biosynthesis";"Phenylpropanoid biosynthesis";"Ephedrine biosynthesis";"Rosmarinic acid biosynthesis I";"Histidine catabolism";"Cinnamoyl-coa biosynthesis";"Phenylalanine metabolism" XP_018906566.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_018914397.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018909116.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_018912672.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018900293.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_018911821.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603 "Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine" XP_018900770.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018913380.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_018899978.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation" XP_018905086.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_018896504.1 9 KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883 "Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II" XP_018899753.1 5 MetaCyc: PWY-6892;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7 "Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism" XP_018914765.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_018911539.1 2 MetaCyc: PWY-7380;KEGG: 00780+2.8.1.6 "Biotin biosynthesis from 8-amino-7-oxononanoate II";"Biotin metabolism" XP_018901601.1 6 Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-7382 "Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" XP_018908861.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018917712.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_018895902.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018901868.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018900002.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_018911363.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_018916730.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_018901776.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_018895997.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018898631.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_018913801.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174430 "DNA replication initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Polymerase switching";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation" XP_018907386.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018911342.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_018916360.1 8 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-6798695;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes" XP_018898239.1 4 KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Glycerophospholipid metabolism";"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_018912879.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_018899988.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-5610787 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Purine metabolism";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Hedgehog 'off' state" XP_018909145.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I" XP_018909585.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018916581.1 14 MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51 "Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism" XP_018914182.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-141444 "Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_018912455.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_018907894.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018905023.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018903949.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_018909135.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_018910722.1 8 MetaCyc: PWY-5739;MetaCyc: PWY-5740;MetaCyc: PWY-7573;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5738;Reactome: R-HSA-6787639;KEGG: 00051+4.2.1.47;MetaCyc: PWY-66 "GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis";"GDP-mycosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)" XP_018900325.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" XP_018896808.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018904380.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_018913461.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_018898164.1 2 Reactome: R-HSA-72764;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"Methylation" XP_018916496.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018917139.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_018902833.1 4 Reactome: R-HSA-964975;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282 "Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_018897163.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_018899084.1 179 Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-937042;Reactome: R-HSA-983168;Reactome: R-HSA-5654733;Reactome: R-HSA-6791226;Reactome: R-HSA-532668;Reactome: R-HSA-2173795;Reactome: R-HSA-912631;Reactome: R-HSA-9013507;Reactome: R-HSA-3769402;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-69541;Reactome: R-HSA-6783310;Reactome: R-HSA-1295596;Reactome: R-HSA-349425;Reactome: R-HSA-174490;Reactome: R-HSA-937072;Reactome: R-HSA-6781827;Reactome: R-HSA-179409;Reactome: R-HSA-9633012;Reactome: R-HSA-3322077;Reactome: R-HSA-8941858;Reactome: R-HSA-1169408;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-6804757;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5696395;Reactome: R-HSA-168928;Reactome: R-HSA-2672351;Reactome: R-HSA-936440;Reactome: R-HSA-8875360;Reactome: R-HSA-8852276;Reactome: R-HSA-182971;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-9646399;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5675221;Reactome: R-HSA-2122947;Reactome: R-HSA-69601;Reactome: R-HSA-5693565;Reactome: R-HSA-1358803;Reactome: R-HSA-450302;Reactome: R-HSA-3134975;Reactome: R-HSA-110320;Reactome: R-HSA-9604323;Reactome: R-HSA-2691232;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-168927;Reactome: R-HSA-168638;Reactome: R-HSA-5689901;Reactome: R-HSA-2559585;Reactome: R-HSA-8849469;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-2644606;Reactome: R-HSA-9637628;Reactome: R-HSA-1236382;Reactome: R-HSA-9636383;Reactome: R-HSA-2559582;Reactome: R-HSA-9013973;Reactome: R-HSA-175474;Reactome: R-HSA-450321;Reactome: R-HSA-6781823;Reactome: R-HSA-5610785;Reactome: R-HSA-5696397;Reactome: R-HSA-975110;Reactome: R-HSA-975163;Reactome: R-HSA-2173788;Reactome: R-HSA-2173791;Reactome: R-HSA-201681;Reactome: R-HSA-5632684;Reactome: R-HSA-5696400;Reactome: R-HSA-1799339;Reactome: R-HSA-5656169;Reactome: R-HSA-72689;Reactome: R-HSA-174178;Reactome: R-HSA-5675482;Reactome: R-HSA-9020702;Reactome: R-HSA-5684264;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-9613829;Reactome: R-HSA-2979096;Reactome: R-HSA-5689877;Reactome: R-HSA-8948747;Reactome: R-HSA-211733;Reactome: R-HSA-72706;Reactome: R-HSA-110312;Reactome: R-HSA-69231;Reactome: R-HSA-9014325;Reactome: R-HSA-5357905;Reactome: R-HSA-68949;Reactome: R-HSA-209543;Reactome: R-HSA-1253288;Reactome: R-HSA-3785653;Reactome: R-HSA-2565942;Reactome: R-HSA-901032;Reactome: R-HSA-445989;Reactome: R-HSA-1169091;Reactome: R-HSA-5689896;Reactome: R-HSA-5358346;Reactome: R-HSA-174048;Reactome: R-HSA-382556;Reactome: R-HSA-9615710;Reactome: R-HSA-6807004;Reactome: R-HSA-5654727;Reactome: R-HSA-917729;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-2122948;Reactome: R-HSA-937039;Reactome: R-HSA-209560;Reactome: R-HSA-8866652;Reactome: R-HSA-75815;Reactome: R-HSA-156827;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-8856828;Reactome: R-HSA-205043;Reactome: R-HSA-6782135;Reactome: R-HSA-5205685;Reactome: R-HSA-5696394;Reactome: R-HSA-5357956;Reactome: R-HSA-5607761;Reactome: R-HSA-2408557;Reactome: R-HSA-4641258;Reactome: R-HSA-4641263;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-6804760;Reactome: R-HSA-2173796;Reactome: R-HSA-9033241;Reactome: R-HSA-68827;Reactome: R-HSA-72764;Reactome: R-HSA-5656121;Reactome: R-HSA-8863795;Reactome: R-HSA-202424;Reactome: R-HSA-6804756;Reactome: R-HSA-5654732;Reactome: R-HSA-5654726;Reactome: R-HSA-9645460;Reactome: R-HSA-8854050;Reactome: R-HSA-975144;Reactome: R-HSA-5676590;Reactome: R-HSA-977225;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-192823;Reactome: R-HSA-936964;Reactome: R-HSA-5678895;Reactome: R-HSA-2894862;Reactome: R-HSA-8876493;Reactome: R-HSA-162588;Reactome: R-HSA-8866654;Reactome: R-HSA-174084;Reactome: R-HSA-110314;Reactome: R-HSA-917937;Reactome: R-HSA-5610780;Reactome: R-HSA-975956;Reactome: R-HSA-8856825;Reactome: R-HSA-156902;Reactome: R-HSA-400253;Reactome: R-HSA-937041;Reactome: R-HSA-975957 "SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"IRAK2 mediated activation of TAK1 complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of FGFR4 signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Regulation of signaling by CBL";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Deactivation of the beta-catenin transactivating complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Stabilization of p53";"Fanconi Anemia Pathway";"Spry regulation of FGF signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Membrane binding and targetting of GAG proteins";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"APC-Cdc20 mediated degradation of Nek2A";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Glycogen synthesis";"Regulation of RUNX3 expression and activity";"ISG15 antiviral mechanism";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of TP53 Degradation";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Formation of Incision Complex in GG-NER";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Stimuli-sensing channels";"Negative regulators of DDX58/IFIH1 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EGFR downregulation";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Aggrephagy";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Negative regulation of MAPK pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Downregulation of ERBB2:ERBB3 signaling";"activated TAK1 mediates p38 MAPK activation";"Regulation of innate immune responses to cytosolic DNA";"Translesion Synthesis by POLH";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"NOD1/2 Signaling Pathway";"Metalloprotease DUBs";"Oncogene Induced Senescence";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Degradation of AXIN";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Modulation by Mtb of host immune system";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Prevention of phagosomal-lysosomal fusion";"Senescence-Associated Secretory Phenotype (SASP)";"TICAM1-dependent activation of IRF3/IRF7";"Assembly Of The HIV Virion";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Formation of TC-NER Pre-Incision Complex";"GLI3 is processed to GLI3R by the proteasome";"Gap-filling DNA repair synthesis and ligation in GG-NER";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TCF dependent signaling in response to WNT";"Hedgehog 'on' state";"Dual Incision in GG-NER";"SRP-dependent cotranslational protein targeting to membrane";"Termination of translesion DNA synthesis";"Formation of a pool of free 40S subunits";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of necroptotic cell death";"Interleukin-1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Chaperone Mediated Autophagy";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Josephin domain DUBs";"Regulation of PTEN localization";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translesion synthesis by REV1";"Cyclin D associated events in G1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of TNFR1 signaling";"Orc1 removal from chromatin";"p75NTR recruits signalling complexes";"Downregulation of ERBB4 signaling";"Myoclonic epilepsy of Lafora";"Regulation of PLK1 Activity at G2/M Transition";"ER Quality Control Compartment (ERQC)";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Activation of NF-kappaB in B cells";"Ovarian tumor domain proteases";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Cyclin B";"ABC-family proteins mediated transport";"Late endosomal microautophagy";"Negative regulation of MET activity";"Negative regulation of FGFR2 signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Activated NOTCH1 Transmits Signal to the Nucleus";"IRAK1 recruits IKK complex";"NF-kB is activated and signals survival";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ubiquitin-dependent degradation of Cyclin D";"L13a-mediated translational silencing of Ceruloplasmin expression";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Clathrin-mediated endocytosis";"NRIF signals cell death from the nucleus";"Dual incision in TC-NER";"Pink/Parkin Mediated Mitophagy";"DNA Damage Recognition in GG-NER";"TNFR1-induced NFkappaB signaling pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Selenocysteine synthesis";"Degradation of DVL";"Regulation of FZD by ubiquitination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Methylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Peroxisomal protein import";"CDT1 association with the CDC6:ORC:origin complex";"Eukaryotic Translation Termination";"Translesion synthesis by POLI";"Downregulation of ERBB2 signaling";"Downstream TCR signaling";"Regulation of TP53 Activity through Phosphorylation";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Alpha-protein kinase 1 signaling pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NIK-->noncanonical NF-kB signaling";"Amyloid fiber formation";"Neddylation";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Viral mRNA Translation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Defective CFTR causes cystic fibrosis";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"InlA-mediated entry of Listeria monocytogenes into host cells";"Budding and maturation of HIV virion";"E3 ubiquitin ligases ubiquitinate target proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Recognition of DNA damage by PCNA-containing replication complex";"Iron uptake and transport";"Degradation of GLI1 by the proteasome";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Cargo recognition for clathrin-mediated endocytosis";"Peptide chain elongation";"Circadian Clock";"IKK complex recruitment mediated by RIP1";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018914471.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018906143.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018910609.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_018907924.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018916523.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375281 "G alpha (q) signalling events";"Hormone ligand-binding receptors" XP_018901638.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_018896675.1 8 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_018914477.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_018896627.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_018899990.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_018897349.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_018907890.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_018900411.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_018915682.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018916410.1 8 MetaCyc: PWY-7524;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;Reactome: R-HSA-2426168 "Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)" XP_018906732.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018915029.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662 "Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling" XP_018898375.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018910566.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_018905658.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018906635.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018904855.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018899954.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_018915585.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_018905325.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_018906488.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_018913941.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_018912100.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018913508.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018915086.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_018908389.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_018907503.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_018912827.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_018906693.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_018915601.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018910737.1 6 Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_018906944.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018916522.1 2 Reactome: R-HSA-375281;Reactome: R-HSA-416476 "Hormone ligand-binding receptors";"G alpha (q) signalling events" XP_018907793.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018916463.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_018901829.1 6 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018913160.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_018905192.1 14 Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426496 "Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs" XP_018895680.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018905653.1 7 MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7210;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-7198;MetaCyc: PWY-6545 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_018913316.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_018906850.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_018914181.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018905617.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_018916382.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-6804115;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_018910367.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018917531.1 8 MetaCyc: PWY-3581;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5049;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5394;MetaCyc: PWY-6133;KEGG: 00350+1.14.16.2;Reactome: R-HSA-209905 "(S)-reticuline biosynthesis I";"Isoquinoline alkaloid biosynthesis";"Rosmarinic acid biosynthesis II";"Folate biosynthesis";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis II";"Tyrosine metabolism";"Catecholamine biosynthesis" XP_018902494.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018896243.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018909656.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_018911210.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_018912157.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018901869.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_018909479.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214 "Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_018905202.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018917894.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_018912665.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_018906016.1 5 Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;MetaCyc: PWY-6277 "Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_018897079.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018900010.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018912223.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6118 "Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Synthesis of PA";"Glycerol-3-phosphate shuttle" XP_018905445.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_018895964.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018907770.1 33 KEGG: 00350+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-6342;KEGG: 00592+1.1.1.1;KEGG: 00010+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-5751;MetaCyc: PWY-6802;MetaCyc: PWY-6587;MetaCyc: PWY-3162;MetaCyc: PWY-5486;MetaCyc: PWY-7396;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-6313;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-7111;MetaCyc: PWY-5078;MetaCyc: PWY-5076;MetaCyc: PWY-6871;KEGG: 00982+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-1801;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-5079;Reactome: R-HSA-71384;MetaCyc: PWY-7118;MetaCyc: PWY-5082;KEGG: 00071+1.1.1.1 "Tyrosine metabolism";"Methane metabolism";"Noradrenaline and adrenaline degradation";"alpha-Linolenic acid metabolism";"Glycolysis / Gluconeogenesis";"Chloroalkane and chloroalkene degradation";"L-valine degradation II";"Phenylethanol biosynthesis";"Salidroside biosynthesis";"Pyruvate fermentation to ethanol III";"L-tryptophan degradation V (side chain pathway)";"Pyruvate fermentation to ethanol II";"Butanol and isobutanol biosynthesis (engineered)";"Metabolism of xenobiotics by cytochrome P450";"Acetaldehyde biosynthesis I";"Serotonin degradation";"Retinol metabolism";"(S)-propane-1,2-diol degradation";"Pyruvate fermentation to isobutanol (engineered)";"L-isoleucine degradation II";"L-leucine degradation III";"3-methylbutanol biosynthesis (engineered)";"Drug metabolism - cytochrome P450";"Naphthalene degradation";"Pyruvate fermentation to ethanol I";"Formaldehyde oxidation II (glutathione-dependent)";"Glycine, serine and threonine metabolism";"Protein S-nitrosylation and denitrosylation";"L-phenylalanine degradation III";"Ethanol oxidation";"Chitin degradation to ethanol";"L-methionine degradation III";"Fatty acid degradation" XP_018910202.1 11 Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_018909591.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_018905317.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018914064.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018910983.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018913782.1 6 KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-7761;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism" XP_018915756.1 10 Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_018912088.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_018895592.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_018896242.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018913125.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_018907875.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_018917901.1 4 KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-5188 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)" XP_018901807.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_018913872.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018904121.1 3 Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269 "Sialic acid metabolism";"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis" XP_018898820.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018899094.1 4 KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118 "Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation" XP_018900627.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018906151.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_018906606.1 18 Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167246 "RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript" XP_018912801.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_018900846.1 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" XP_018906150.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018907478.1 19 Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-114604;Reactome: R-HSA-389359;Reactome: R-HSA-8950505;Reactome: R-HSA-983231;Reactome: R-HSA-5626467;Reactome: R-HSA-428543;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-194840;Reactome: R-HSA-8964616;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5627123;Reactome: R-HSA-5687128;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662 "EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"GPVI-mediated activation cascade";"CD28 dependent Vav1 pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate IQGAPs";"Inactivation of CDC42 and RAC1";"Myogenesis";"DCC mediated attractive signaling";"Rho GTPase cycle";"G beta:gamma signalling through CDC42";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate PAKs";"MAPK6/MAPK4 signaling";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling" XP_018902757.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018911272.1 3 Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_018910987.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_018909265.1 5 MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981 "L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)" XP_018914825.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597 "Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events" XP_018913292.1 42 Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-9610379;Reactome: R-HSA-3214847;Reactome: R-HSA-427359;Reactome: R-HSA-73728;Reactome: R-HSA-5334118;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-1912408;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-9616222;Reactome: R-HSA-5625886;Reactome: R-HSA-3214841;Reactome: R-HSA-69473;Reactome: R-HSA-977225;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-171306;Reactome: R-HSA-2559582 "Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Late Events";"HATs acetylate histones";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"DNA methylation";"SUMOylation of chromatin organization proteins";"Meiotic synapsis";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"Transcriptional regulation of granulopoiesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PKMTs methylate histone lysines";"G2/M DNA damage checkpoint";"Amyloid fiber formation";"PRC2 methylates histones and DNA";"HCMV Early Events";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Packaging Of Telomere Ends";"Senescence-Associated Secretory Phenotype (SASP)" XP_018910432.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_018899611.1 7 KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Choline biosynthesis III";"Synthesis of PG";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism";"Synthesis of PA" XP_018898481.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_018895758.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_018907444.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_018901438.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018899230.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-167590 "ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation" XP_018910161.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_018902525.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_018908356.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_018903757.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901107.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490 "Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Collagen degradation" XP_018910818.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72702 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition" XP_018896628.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_018897840.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_018909872.1 3 MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403 "5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_018915293.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_018896017.1 4 MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" XP_018900648.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_018911600.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018900142.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_018902961.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018899394.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018904212.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018903724.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018915897.1 3 Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1" XP_018914247.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" XP_018904149.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408 "Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation" XP_018901399.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_018909044.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018900723.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_018912385.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018897192.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_018902981.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018904468.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_018897410.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402 "Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex" XP_018896075.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_018901515.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_018903988.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018900879.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_018898899.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018900807.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_018913542.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018909667.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018915805.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_018903405.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018912280.1 4 Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807062 "Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol" XP_018899514.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_018916924.1 8 KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982 "Purine metabolism";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor" XP_018908704.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018902797.1 7 Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61 "Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Citrate cycle (TCA cycle)" XP_018898271.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_018915886.1 4 Reactome: R-HSA-4755583;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199 "Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate" XP_018900328.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_018903100.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_018901925.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018901965.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_018912402.1 7 MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11 "Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Methane metabolism" XP_018902124.1 2 Reactome: R-HSA-430039;MetaCyc: PWY-6938 "mRNA decay by 5' to 3' exoribonuclease";"NADH repair" XP_018911308.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_018900161.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_018899261.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_018904038.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603 "Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine" XP_018913190.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018898039.1 1 KEGG: 00565+3.1.1.47 "Ether lipid metabolism" XP_018897755.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_018897649.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_018898297.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018896769.1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis" XP_018917264.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I" XP_018896062.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Peptide chain elongation" XP_018898438.1 5 Reactome: R-HSA-1660499;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6368 "Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation" XP_018911908.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018907623.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_018904089.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018907773.1 6 KEGG: 00380+1.14.13.9;MetaCyc: PWY-5651;Reactome: R-HSA-71240;MetaCyc: PWY-7717;MetaCyc: PWY-6309;MetaCyc: PWY-7765 "Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II" XP_018900513.1 7 KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22 "Glutathione metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism" XP_018909107.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_018898692.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_018908141.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018903565.1 17 MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;Reactome: R-HSA-196780;Reactome: R-HSA-163765;MetaCyc: PWY-5789;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-6722;Reactome: R-HSA-3371599 "Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Glyoxylate assimilation";"Pyruvate metabolism";"Carnitine metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"Jadomycin biosynthesis";"Candicidin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency" XP_018913733.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_018904814.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_018902831.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_018900294.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_018899723.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_018904366.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597 "Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events" XP_018915593.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018910095.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018911924.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018914525.1 24 Reactome: R-HSA-432040;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-416482;Reactome: R-HSA-418592;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-500657;Reactome: R-HSA-418594 "Vasopressin regulates renal water homeostasis via Aquaporins";"Ca2+ pathway";"G-protein activation";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 1";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events" XP_018917000.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_018900486.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"Kinesins";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Separation of Sister Chromatids";"Gap junction assembly";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion" XP_018914820.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"PKA activation";"Purine metabolism";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_018901444.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018913175.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_018912853.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018902621.1 10 KEGG: 00510+2.4.1.83;MetaCyc: PWY-7921;MetaCyc: PWY-7661;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-913709;Reactome: R-HSA-162699;MetaCyc: PWY-7979;MetaCyc: PWY-7922 "N-Glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_018902670.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018909899.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_018901992.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018900480.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018916917.1 12 Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-399719;Reactome: R-HSA-9609736 "Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"RAF/MAP kinase cascade";"Purine metabolism";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors" XP_018904769.1 6 Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-8951664;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Neddylation";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex" XP_018907951.1 6 MetaCyc: PWY-6922;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344 "L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)" XP_018902956.1 29 Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-3371453;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-3108214;Reactome: R-HSA-912446;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-3371511;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-68962 "Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Regulation of HSF1-mediated heat shock response";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"SUMOylation of DNA damage response and repair proteins";"Meiotic recombination";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"HSF1 activation";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex" XP_018901673.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018912274.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_018899902.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018910400.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913902.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_018904150.1 14 Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944 "Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2" XP_018915419.1 10 Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590 "MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Neddylation";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling" XP_018901474.1 5 Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131 "Collagen degradation";"MHC class II antigen presentation";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR" XP_018907340.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018897989.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex" XP_018908790.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018911523.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_018912336.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018911151.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018899830.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_018911171.1 1 Reactome: R-HSA-1234174 "Cellular response to hypoxia" XP_018913845.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018911333.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018903907.1 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" XP_018899901.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018897175.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_018900140.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_018916420.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_018914551.1 13 Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101 "Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"CS/DS degradation" XP_018914593.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_018899603.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018905075.1 31 MetaCyc: PWY-4381;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7858;MetaCyc: PWY-6519;MetaCyc: PWY-5973;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWYG-321;MetaCyc: PWY-8049;Reactome: R-HSA-199220;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-7746;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7723;MetaCyc: PWY-7663;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-5367;MetaCyc: PWY-5142;Reactome: R-HSA-2426168;MetaCyc: PWY-5994;MetaCyc: PWY-6282 "Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"";"Pederin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mycobacterial sulfolipid biosynthesis";"Biotin metabolism";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)" XP_018917060.1 4 Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping" XP_018904755.1 4 KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation" XP_018917982.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_018897612.1 11 KEGG: 00720+1.1.1.42;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-5913;MetaCyc: PWY-7268;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-7124;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.42 "Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)" XP_018899815.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018918231.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_018917401.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_018914591.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_018912697.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_018899355.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_018916692.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_018910549.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_018914921.1 15 Reactome: R-HSA-5358752;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747 "T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated" XP_018908992.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018904358.1 10 KEGG: 00330+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41 "Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism" XP_018907383.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72702 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition" XP_018911334.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_018896193.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_018916946.1 24 Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-416482;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-400042 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G alpha (12/13) signalling events";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"G alpha (z) signalling events";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion" XP_018907462.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_018913857.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018917434.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_018901617.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018899538.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_018900816.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_018898000.1 6 KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685 "Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species" XP_018896855.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018915481.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018916896.1 5 MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817 "CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_018899977.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018907777.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_018906617.1 6 KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221 "Pentose phosphate pathway";"Sorbitol biosynthesis II";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_018916792.1 4 Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228 "Crosslinking of collagen fibrils";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix" XP_018912704.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_018914895.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation" XP_018902721.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018902331.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_018913135.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_018898627.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_018898622.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_018909091.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-2132295 "Antigen processing: Ubiquitination & Proteasome degradation";"MHC class II antigen presentation" XP_018902256.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828 "MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis" XP_018909922.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_018903621.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_018895655.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018898231.1 10 MetaCyc: PWY-6397;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-7344 "Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis" XP_018898658.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_018918238.1 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_018912294.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_018900724.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214 "Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_018904151.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408 "Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation" XP_018907976.1 6 Reactome: R-HSA-1489509;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;Reactome: R-HSA-418597 "DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"G alpha (z) signalling events" XP_018913545.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_018914376.1 6 MetaCyc: PWY-7433;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290 "Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis" XP_018897276.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_018907690.1 12 Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-418885;KEGG: 04150+2.7.11.1 "Rho GTPase cycle";"G alpha (q) signalling events";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"mTOR signaling pathway" XP_018896662.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018914029.1 5 Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_018918279.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018904283.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018899606.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" XP_018911159.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018905628.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_018916665.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018897380.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_018906297.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_018896089.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018909363.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_018900979.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018897998.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_018909422.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018906049.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018897583.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_018902637.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018901665.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018913358.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_018905578.1 5 KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-7761 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)" XP_018914021.1 17 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;Reactome: R-HSA-5685938;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-1221632;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"HDR through Single Strand Annealing (SSA)";"Human cytomegalovirus infection";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Meiotic synapsis";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_018909545.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018898120.1 10 KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11 "Methane metabolism";"Galactose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis" XP_018901664.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018914858.1 6 Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-9640463;Reactome: R-HSA-75105 "ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Wax biosynthesis";"Fatty acyl-CoA biosynthesis" XP_018896996.1 3 Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228 "Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix" XP_018906960.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_018917067.1 10 MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-4041 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle" XP_018905190.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018899009.1 6 Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363 "Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_018903187.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018897639.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018904211.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_018914368.1 13 MetaCyc: PWY-6370;MetaCyc: PWY-7112;Reactome: R-HSA-196836;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1 "Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Vitamin C (ascorbate) metabolism";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Ascorbate glutathione cycle";"Glutathione metabolism" XP_018900613.1 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" XP_018901149.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_018907955.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018896692.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018916539.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018900528.1 5 KEGG: 00750+2.7.1.35;MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-6798695;Reactome: R-HSA-964975 "Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate" XP_018907179.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_018900868.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_018914854.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_018917542.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_018896161.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018899528.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_018912261.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_018906580.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018902904.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018909804.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018917285.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_018899178.1 14 MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8051 "Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I" XP_018910516.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway" XP_018908957.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018904190.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815 "Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones" XP_018915754.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018911309.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018918259.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018897839.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_018913381.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_018905417.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_018901369.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018903869.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_018914087.1 7 MetaCyc: PWY-5188;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-6782315 "Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"tRNA modification in the nucleus and cytosol" XP_018904785.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-3065676;Reactome: R-HSA-3065678 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)" XP_018917450.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_018900808.1 19 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-3214858;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-8876725 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"RMTs methylate histone arginines";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Protein methylation" XP_018897946.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018902262.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" XP_018900194.1 25 Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-381771;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-392851;Reactome: R-HSA-8964315;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-416482;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-428930 "Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"Ca2+ pathway";"G-protein activation";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G alpha (z) signalling events";"G alpha (s) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through BTK";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor" XP_018912940.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" XP_018917081.1 4 MetaCyc: PWY-2942;MetaCyc: PWY-2941;KEGG: 00300+4.1.1.20;MetaCyc: PWY-5097 "L-lysine biosynthesis III";"L-lysine biosynthesis II";"Lysine biosynthesis";"L-lysine biosynthesis VI" XP_018906342.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_018911250.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_018899297.1 9 Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-3928662 "Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling" XP_018910401.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018906069.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_018917106.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_018896459.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_018905549.1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332 "Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Kinesins";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin" XP_018906185.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_018902723.1 4 Reactome: R-HSA-1234176;Reactome: R-HSA-3232142;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SUMOylation of ubiquitinylation proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_018910993.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_018914207.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_018915271.1 15 Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593 "Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity" XP_018898180.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018908630.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018898244.1 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" XP_018916889.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_018916146.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_018902125.1 11 MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00500+3.6.1.9 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Tunicamycin biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Starch and sucrose metabolism" XP_018908659.1 13 Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802948 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Relaxin signaling pathway";"Signaling downstream of RAS mutants";"Human cytomegalovirus infection";"Human papillomavirus infection";"Signaling by moderate kinase activity BRAF mutants";"Thermogenesis";"PI3K-Akt signaling pathway";"Signaling by BRAF and RAF fusions";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Signaling by high-kinase activity BRAF mutants" XP_018905205.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_018916349.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_018907842.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_018917266.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_018914018.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018896798.1 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_018915738.1 20 Reactome: R-HSA-3371571;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389357 "HSF1-dependent transactivation";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"Regulation of PTEN gene transcription";"Thermogenesis";"mTOR signaling pathway";"mTOR signalling";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Human papillomavirus infection";"Macroautophagy";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"CD28 dependent PI3K/Akt signaling" XP_018901810.1 30 KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8941332;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-9634638;Reactome: R-HSA-6804759;Reactome: R-HSA-1358803;Reactome: R-HSA-6804757;Reactome: R-HSA-8948751;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-198693;Reactome: R-HSA-199418;Reactome: R-HSA-9614399;Reactome: R-HSA-69656;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-111447;Reactome: R-HSA-211163;Reactome: R-HSA-5628897;Reactome: R-HSA-6804758;Reactome: R-HSA-8876198;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69202 "Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"RUNX2 regulates genes involved in cell migration";"PI3K-Akt signaling pathway";"CTLA4 inhibitory signaling";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of TP53 Activity through Association with Co-factors";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of TP53 Degradation";"Regulation of PTEN stability and activity";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"AKT phosphorylates targets in the nucleus";"Negative regulation of the PI3K/AKT network";"Regulation of localization of FOXO transcription factors";"Cyclin A:Cdk2-associated events at S phase entry";"mTOR signaling pathway";"Relaxin signaling pathway";"Activation of BAD and translocation to mitochondria";"AKT-mediated inactivation of FOXO1A";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Acetylation";"RAB GEFs exchange GTP for GDP on RABs";"Human cytomegalovirus infection";"Cyclin E associated events during G1/S transition" XP_018917231.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_018916707.1 5 Reactome: R-HSA-166208;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-165159 "mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"mTOR signalling" XP_018896540.1 5 MetaCyc: PWY-6098;KEGG: 00909+4.2.1.129+5.4.99.17;Reactome: R-HSA-191273;MetaCyc: PWY-7072;Reactome: R-HSA-2426168 "Diploterol biosynthesis";"Sesquiterpenoid and triterpenoid biosynthesis";"Cholesterol biosynthesis";"Hopanoid biosynthesis (bacteria)";"Activation of gene expression by SREBF (SREBP)" XP_018902277.1 13 Reactome: R-HSA-532668;Reactome: R-HSA-3371511;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-9646399;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-5689877;Reactome: R-HSA-8876725;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8866654 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"HSF1 activation";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"Aggrephagy";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Josephin domain DUBs";"Protein methylation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"E3 ubiquitin ligases ubiquitinate target proteins" XP_018903098.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_018906674.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018910680.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018905718.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_018900275.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018918101.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_018901663.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018918248.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018902057.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018911571.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_018912593.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018910580.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018901306.1 26 Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-2644606;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-5621575;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1234158 "Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Attenuation phase";"Circadian Clock";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"CD209 (DC-SIGN) signaling";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor" XP_018909882.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018899268.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018910389.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018917928.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018914316.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" XP_018913492.1 12 MetaCyc: PWY-5857;MetaCyc: PWY-6978;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-5873;Reactome: R-HSA-1268020;MetaCyc: PWY-5870;MetaCyc: PWY-5871;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6708 "Ubiquinol-10 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_018917021.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_018916414.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_018916548.1 6 KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148;MetaCyc: PWY-7817;Reactome: R-HSA-1483166;MetaCyc: PWY-5668;MetaCyc: PWY-5269 "Glycerophospholipid metabolism";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PA";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II" XP_018900708.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018904632.1 10 KEGG: 00710+2.7.2.3;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-6886;Reactome: R-HSA-70171 "Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis" XP_018906063.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_018900387.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829 "Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_018915853.1 56 Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-75815 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D" XP_018907768.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706 "Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_018917215.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_018913946.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018901737.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_018902552.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_018900697.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_018911166.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018896431.1 4 Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_018908424.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018900720.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018912497.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_018897353.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_018911357.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_018901730.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018917951.1 9 KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_018907264.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_018897970.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_018904876.1 7 Reactome: R-HSA-1483226;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-7625;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351 "Synthesis of PI";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_018906417.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018902056.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018895699.1 4 KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963 "Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I" XP_018916300.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_018905269.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_018900634.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_018903392.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_018912395.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_018899333.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018913861.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018902129.1 5 KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism" XP_018904136.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018916738.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018908912.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_018898370.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_018902921.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_018906070.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_018916143.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288 "mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1" XP_018901152.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_018905033.1 42 MetaCyc: PWY-5109;MetaCyc: PWY-7778;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-6435;MetaCyc: PWY-5138;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-7007;MetaCyc: PWY-6946;MetaCyc: PWY-7654;MetaCyc: PWY-6945;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-6583;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7094;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-7606;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00623+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00627+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-5789;MetaCyc: PWY-7401;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35 "Fermentation to 2-methylbutanoate";"2-methylpropene degradation";"Lysine degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Carbon fixation pathways in prokaryotes";"Geraniol degradation";"Propanoate metabolism";"Pyruvate fermentation to hexanol (engineered)";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Limonene and pinene degradation";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol I";"Fatty acid elongation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid salvage";"Butanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Toluene degradation";"Phenylalanine metabolism";"Fatty acid degradation";"Methyl tert-butyl ether degradation";"Aminobenzoate degradation";"Caprolactam degradation";"Tryptophan metabolism";"Spodoptera littoralis pheromone biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"alpha-Linolenic acid metabolism";"Androstenedione degradation";"Valine, leucine and isoleucine degradation";"beta-Alanine metabolism";"Fatty acid degradation" XP_018898026.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_018914190.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018904875.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_018896402.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018908721.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018917953.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018914185.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018902391.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_018906536.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018896848.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901805.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" XP_018908725.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018915262.1 13 KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198 "Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_018897242.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018896237.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018902755.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018913501.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018917430.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_018915588.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_018900516.1 7 KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22 "Glutathione metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism" XP_018895878.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018904082.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_018902931.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_018907576.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_018899078.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_018896828.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018903750.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018901054.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_018915418.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" XP_018913854.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018900292.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018896399.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018915132.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018909421.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018897468.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018909340.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018900776.1 4 MetaCyc: PWY-7174;Reactome: R-HSA-72731;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_018913323.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_018913815.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018900948.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_018906878.1 6 MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_018899270.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913054.1 11 Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-3214847 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones" XP_018914476.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_018907697.1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346 "ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis" XP_018912186.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_018917818.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)" XP_018911503.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_018899734.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_018902359.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_018906276.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_018906425.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018916920.1 12 Reactome: R-HSA-9609736;Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-8849932 "Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Long-term potentiation";"NrCAM interactions";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules" XP_018913603.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_018916664.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018899560.1 12 KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"Activation of AMPK downstream of NMDARs";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Macroautophagy";"mTOR signaling pathway" XP_018912081.1 6 KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism" XP_018901105.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018914464.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018908603.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018902587.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" XP_018909518.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018906370.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_018898644.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_018904417.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018901565.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" XP_018914410.1 6 KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221 "Pentose phosphate pathway";"Caprolactam degradation";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_018904549.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018903069.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_018910617.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_018914252.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels" XP_018916298.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_018903200.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system" XP_018903517.1 4 MetaCyc: PWY-7849;KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691;MetaCyc: PWY-7394 "Urate conversion to allantoin III";"Purine metabolism";"Urate conversion to allantoin I";"Urate conversion to allantoin II" XP_018910193.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_018916542.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism" XP_018909903.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_018916649.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_018905361.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_018901517.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_018913272.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_018903467.1 3 KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_018912869.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018908159.1 13 MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5 "Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism" XP_018912288.1 5 Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_018914435.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_018911726.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_018913780.1 6 MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_018902693.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_018911460.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018914844.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018910000.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_018904152.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018900180.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018917797.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_018896234.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018904912.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_018909599.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018916793.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_018906164.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_018912702.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_018902233.1 10 MetaCyc: PWY-5849;MetaCyc: PWY-5844;Reactome: R-HSA-2142789;MetaCyc: PWY-7996;MetaCyc: PWY-5895;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5839;MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-5892 "Menaquinol-6 biosynthesis";"Menaquinol-9 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-13 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-12 biosynthesis" XP_018897394.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018906051.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018909144.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080 "Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I" XP_018901854.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619 "Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis" XP_018900165.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018911314.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_018900382.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018912500.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_018915884.1 10 KEGG: 00410+2.6.1.19;Reactome: R-HSA-916853;MetaCyc: PWY-6537;KEGG: 00640+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-5022;KEGG: 00650+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-6535 "beta-Alanine metabolism";"Degradation of GABA";"4-aminobutanoate degradation II";"Propanoate metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation V";"Butanoate metabolism";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation III";"4-aminobutanoate degradation I" XP_018917654.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" XP_018912027.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018897143.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_018896240.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018906504.1 24 Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-6814122 "Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"Ca2+ pathway";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_018897641.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018916709.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_018915991.1 5 KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" XP_018898612.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018907831.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018896697.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018903379.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_018913907.1 3 Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793 "RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis" XP_018906396.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018909086.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167162 "Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape" XP_018912300.1 4 Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399 "Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Aggrephagy" XP_018898048.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_018899006.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018899238.1 13 Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809 "Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization" XP_018911112.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018917360.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018917457.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018901924.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018914864.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018916027.1 7 Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-8943724;Reactome: R-HSA-983231;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519 "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN gene transcription";"Factors involved in megakaryocyte development and platelet production";"HDMs demethylate histones";"Estrogen-dependent gene expression" XP_018896088.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018904810.1 19 KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-1622;Reactome: R-HSA-70263;MetaCyc: PWY-8086;MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-561 "Cysteine and methionine metabolism";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"Pyruvate metabolism";"Methane metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_018897624.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018910506.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018904970.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_018915551.1 5 Reactome: R-HSA-4755579;MetaCyc: PWY-6129;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199 "Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate" XP_018900504.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_018902958.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_018902326.1 5 Reactome: R-HSA-1482883;Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20 "Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis" XP_018900659.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607 "G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends" XP_018904988.1 3 Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542 "RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation" XP_018901656.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_018902362.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_018911970.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_018901406.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018912024.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018909896.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018898573.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_018900479.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018899264.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018898439.1 5 Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580;MetaCyc: PWY-6368 "Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation" XP_018902834.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_018911230.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_018915944.1 12 Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-427413;Reactome: R-HSA-73762 "RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_018917961.1 2 KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26 "Galactose metabolism";"Starch and sucrose metabolism" XP_018901627.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_018902855.1 5 Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310 "HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway" XP_018910370.1 6 Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018900942.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018909317.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_018912094.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018912405.1 40 Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-5578749;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-6803529 "mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcriptional regulation by small RNAs";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"FGFR2 alternative splicing" XP_018904361.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_018918159.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018917497.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018918269.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_018902195.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-156581 "Ub-specific processing proteases";"Methylation" XP_018906980.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_018909336.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018906267.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_018910665.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_018901853.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619 "Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis" XP_018896414.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018914406.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_018903853.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_018898387.1 4 KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines" XP_018896766.1 31 MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-5994;MetaCyc: PWY-6282;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;MetaCyc: PWYG-321;MetaCyc: PWY-6113;MetaCyc: PWY-8049;MetaCyc: PWY-7746;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-9029558;MetaCyc: PWY-8012;MetaCyc: PWY-5973;Reactome: R-HSA-163765;MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6519;MetaCyc: PWY-7858;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-7723 "Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"";"Superpathway of mycolate biosynthesis";"Pederin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Biotin metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mupirocin biosynthesis";"Cis-vaccenate biosynthesis";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence" XP_018912694.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_018907603.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018906744.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_018913021.1 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_018900553.1 4 Reactome: R-HSA-3359462;Reactome: R-HSA-3359463;Reactome: R-HSA-196741;Reactome: R-HSA-8964011 "Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance" XP_018907510.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018910990.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_018915658.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;MetaCyc: PWY-7199;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556 "Neutrophil degranulation";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II" XP_018911181.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018913831.1 4 Reactome: R-HSA-4719377;Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360 "Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)" XP_018906690.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_018914570.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_018903367.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018905029.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018896223.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5461 "Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Betanidin degradation" XP_018918013.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018913027.1 5 Reactome: R-HSA-2173789;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5689603;Reactome: R-HSA-8856825 "TGF-beta receptor signaling activates SMADs";"Neddylation";"Iron uptake and transport";"UCH proteinases";"Cargo recognition for clathrin-mediated endocytosis" XP_018917277.1 20 Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756 "Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation" XP_018913004.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_018913717.1 5 Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787;Reactome: R-HSA-373080 "BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Activation of SMO";"Hedgehog 'off' state";"Class B/2 (Secretin family receptors)" XP_018906093.1 5 Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_018903779.1 10 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Ub-specific processing proteases";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Human cytomegalovirus infection" XP_018914150.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_018909055.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018908237.1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I" XP_018899501.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_018913159.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_018907044.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_018901920.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_018913790.1 9 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis" XP_018913127.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_018906608.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018918099.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_018900133.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_018897512.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018898989.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-428540 "Downstream signal transduction";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Activation of RAC1" XP_018895735.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_018900878.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Translation initiation complex formation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_018911227.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018915136.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_018901912.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_018917736.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018900123.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590 "Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling" XP_018896529.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_018905914.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018911102.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018901265.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_018909376.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_018918093.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018900962.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_018900050.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018899959.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-9020702 "Neutrophil degranulation";"Interleukin-1 signaling" XP_018910991.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018906583.1 57 Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603 "Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Degradation of AXIN";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Neddylation";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"UCH proteinases" XP_018917909.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_018900746.1 17 Reactome: R-HSA-1538133;Reactome: R-HSA-113501;Reactome: R-HSA-1362300;Reactome: R-HSA-139915;Reactome: R-HSA-2559580;Reactome: R-HSA-1362277;Reactome: R-HSA-2559585;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408;Reactome: R-HSA-69202;Reactome: R-HSA-6804114;Reactome: R-HSA-9616222;Reactome: R-HSA-69231;Reactome: R-HSA-111448;Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69205 "G0 and Early G1";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Activation of PUMA and translocation to mitochondria";"Oxidative Stress Induced Senescence";"Transcription of E2F targets under negative control by DREAM complex";"Oncogene Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation";"Cyclin E associated events during G1/S transition";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional regulation of granulopoiesis";"Cyclin D associated events in G1";"Activation of NOXA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription" XP_018902695.1 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_018911196.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_018918052.1 56 Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-174184 "Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Degradation of AXIN";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Neddylation";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_018899833.1 14 Reactome: R-HSA-3769402;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-2173788;Reactome: R-HSA-450520;Reactome: R-HSA-9648025;Reactome: R-HSA-5687128;Reactome: R-HSA-165054;Reactome: R-HSA-141444 "Deactivation of the beta-catenin transactivating complex";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"Downregulation of TGF-beta receptor signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"EML4 and NUDC in mitotic spindle formation";"MAPK6/MAPK4 signaling";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_018918077.1 13 MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5537 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Pyruvate fermentation to acetate V" XP_018897969.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_018911088.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_018909105.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_018916768.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018914015.1 6 Reactome: R-HSA-9022537;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781 "Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"PPARA activates gene expression" XP_018896615.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018910691.1 24 Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-2730905;Reactome: R-HSA-5218920;Reactome: R-HSA-9634635;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-354192;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-444257;Reactome: R-HSA-202424;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-114604;KEGG: 04926+2.7.11.1 "CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated vascular permeability";"Estrogen-stimulated signaling through PRKCZ";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Integrin signaling";"mTOR signaling pathway";"Activation of AKT2";"Thermogenesis";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"RSK activation";"Downstream TCR signaling";"Human cytomegalovirus infection";"VEGFR2 mediated cell proliferation";"GPVI-mediated activation cascade";"Relaxin signaling pathway" XP_018909592.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_018917194.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_018896454.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018897027.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018914498.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018911354.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018901269.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_018898807.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_018912169.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018907136.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_018909402.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_018896852.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901497.1 7 MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_018915274.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_018916776.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018909910.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018909990.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_018895729.1 5 Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs" XP_018913460.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_018914259.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_018906818.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_018917902.1 4 MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75 "Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_018906475.1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" XP_018912292.1 5 KEGG: 00100+2.5.1.21;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;KEGG: 00909+2.5.1.21 "Steroid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Sesquiterpenoid and triterpenoid biosynthesis" XP_018914334.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_018902717.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018914556.1 7 Reactome: R-HSA-1474151;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-69205;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines";"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"Folate transformations II (plants)";"One carbon pool by folate" XP_018908657.1 10 MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826 "Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis" XP_018914772.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_018900911.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018903260.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018901482.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018901919.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852 "Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy" XP_018909799.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_018902511.1 6 Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980 "Mitochondrial protein import";"Photosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"ATP biosynthesis" XP_018916912.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;MetaCyc: PWY-7221 "Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Purine metabolism";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis" XP_018897929.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-380994 "PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_018916304.1 5 Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-2426168 "Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)" XP_018901540.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_018898806.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_018900880.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018905579.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018896973.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018896749.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018901124.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_018915637.1 4 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-3371453;Reactome: R-HSA-8950505 "Cristae formation";"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_018905916.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018917475.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_018898166.1 2 KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_018896470.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163359 "G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation" XP_018911404.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_018916421.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_018906902.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018902920.1 4 KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847 "Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones" XP_018909967.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_018898905.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018900279.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_018906745.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_018909499.1 12 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Glycerophospholipid metabolism" XP_018902622.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_018911545.1 8 KEGG: 00360+4.3.1.24;MetaCyc: PWY-6457;Reactome: R-HSA-70921;MetaCyc: PWY-5048;KEGG: 00940+4.3.1.24;MetaCyc: PWY-5883;MetaCyc: PWY-1121;MetaCyc: PWY-6444 "Phenylalanine metabolism";"Cinnamoyl-coa biosynthesis";"Histidine catabolism";"Rosmarinic acid biosynthesis I";"Phenylpropanoid biosynthesis";"Ephedrine biosynthesis";"Suberin monomers biosynthesis";"Benzoate biosynthesis II (CoA-independent, non-beta-oxidative)" XP_018899239.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_018899542.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_018902991.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_018897836.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_018914543.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_018898618.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619 "Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis" XP_018914746.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_018910418.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_018903985.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018897262.1 10 Reactome: R-HSA-983231;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6365;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6554;MetaCyc: PWY-6366;KEGG: 04070+2.7.1.159;Reactome: R-HSA-1855204 "Factors involved in megakaryocyte development and platelet production";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol" XP_018912138.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018903176.1 5 Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221 "Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway" XP_018903940.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_018904324.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018906420.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_018916643.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_018914380.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018898192.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_018911241.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_018916591.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018906648.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018911047.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018915699.1 7 Reactome: R-HSA-171306;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-1221632 "Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis" XP_018911069.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_018905702.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018913608.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018903474.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018916999.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_018899088.1 4 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300 "DNA methylation";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA" XP_018917163.1 7 Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178 "O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans" XP_018901370.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018907709.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018902261.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656 "Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling" XP_018906046.1 57 Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Neddylation";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of AXIN";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"UCH proteinases";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_018904018.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_018906962.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_018901775.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_018901477.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_018905604.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018915942.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" XP_018897053.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018911745.1 4 MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_018902960.1 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_018907417.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_018906330.1 7 KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism" XP_018909187.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580 "mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence" XP_018901092.1 10 MetaCyc: PWY-8053;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411 "Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)" XP_018914744.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018902666.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_018909090.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-2132295 "Antigen processing: Ubiquitination & Proteasome degradation";"MHC class II antigen presentation" XP_018918236.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_018909113.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018900825.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_018908156.1 5 MetaCyc: PWY-7185;Reactome: R-HSA-6798695;MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6 "UTP and CTP dephosphorylation I";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Purine metabolism" XP_018916865.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_018910512.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation" XP_018915575.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_018898995.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018916614.1 3 Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420 "Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)" XP_018905620.1 18 Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167243 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery" XP_018900471.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation" XP_018913994.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_018902349.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_018914888.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601 "Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_018896750.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018903855.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_018900861.1 17 Reactome: R-HSA-937042;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-975163;Reactome: R-HSA-168638;Reactome: R-HSA-9014325;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-9645460;Reactome: R-HSA-1169091;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-937072;Reactome: R-HSA-5607764 "IRAK2 mediated activation of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Downstream TCR signaling";"Ub-specific processing proteases";"Alpha-protein kinase 1 signaling pathway";"Activation of NF-kappaB in B cells";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling" XP_018910028.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_018900318.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214 "Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs" XP_018898079.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_018904286.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018907878.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_018917847.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_018898275.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018906582.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I" XP_018897999.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017 "Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_018911316.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018907604.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018897542.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_018907263.1 29 Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-5696400;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-72086 "Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Dual Incision in GG-NER";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping" XP_018917622.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_018898011.1 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_018900586.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018906540.1 7 KEGG: 00620+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268 "Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism" XP_018901828.1 6 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;Reactome: R-HSA-400253 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Circadian Clock" XP_018901750.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018911995.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_018907950.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_018917864.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_018901963.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_018910696.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_018909068.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_018914907.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018898602.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_018897148.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_018911377.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018904008.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018908400.1 8 Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-3371571 "mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation" XP_018911179.1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" XP_018896400.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018899090.1 4 Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37 "DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism" XP_018908303.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018902460.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018903354.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_018910477.1 4 KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_018904158.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_018903417.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018902657.1 5 KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4 "Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Butanoate metabolism";"Geraniol degradation";"Valine, leucine and isoleucine degradation" XP_018909651.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-418594 "G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G alpha (i) signalling events" XP_018897026.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018905989.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018898113.1 10 KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11 "Galactose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism" XP_018906570.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018916460.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_018898821.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018903574.1 3 Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271 "GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism" XP_018900410.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_018899890.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_018909270.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_018912711.1 17 MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7176 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis" XP_018909406.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_018903942.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_018908261.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018904874.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781 "ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression" XP_018900791.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-5461 "Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation" XP_018904421.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018918071.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018911725.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_018897544.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_018897944.1 11 Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-1963642;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795 "RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling" XP_018905299.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex" XP_018917800.1 4 KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_018906427.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_018900681.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018905273.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018899802.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_018903073.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018898483.1 5 Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_018898926.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978 "Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production" XP_018915659.1 13 KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456;KEGG: 00051+5.3.1.8;Reactome: R-HSA-1268020;Reactome: R-HSA-446205;Reactome: R-HSA-1362409;MetaCyc: PWY-5659;MetaCyc: PWY-6992;MetaCyc: PWY-3861;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-3881 "Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Mitochondrial protein import";"Synthesis of GDP-mannose";"Mitochondrial iron-sulfur cluster biogenesis";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"Mannitol degradation II";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis" XP_018913456.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" XP_018896411.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018914444.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_018917265.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_018896532.1 4 Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260 "Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_018917304.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_018906539.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018900796.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469 "Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis" XP_018914399.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_018908978.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018900976.1 18 Reactome: R-HSA-6798695;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;Reactome: R-HSA-163765;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-7384;Reactome: R-HSA-75105;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5172;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5 "Neutrophil degranulation";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Methylaspartate cycle";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes" XP_018897633.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018917680.1 19 Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-202733 "Regulation of TLR by endogenous ligand";"VLDL assembly";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Chylomicron assembly";"LDL remodeling";"Scavenging by Class A Receptors";"Chylomicron remodeling";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall" XP_018913318.1 4 Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202 "Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition" XP_018908377.1 13 MetaCyc: PWY-7709;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-7736;MetaCyc: PWY-5122;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7721 "(3R)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis";"Geranyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis" XP_018916921.1 12 Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-8849932 "Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"NrCAM interactions";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules" XP_018896082.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_018897491.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_018912282.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_018905461.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_018902200.1 14 MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601 "Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_018907145.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018903975.1 14 MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587 "Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)" XP_018908863.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_018900672.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_018896541.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_018912514.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_018895849.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018903691.1 18 Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-6803 "Synthesis of PA";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing" XP_018911330.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_018909494.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_018915552.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_018905149.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018907575.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_018917907.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018909114.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" XP_018912001.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018902516.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018902387.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_018898262.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_018909230.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_018901751.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018904678.1 14 MetaCyc: PWY-1622;MetaCyc: PWY-3661-1;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-2161;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3841 "Formaldehyde assimilation I (serine pathway)";"Glycine betaine degradation II (mammalian)";"Metabolism of folate and pterines";"Folate transformations I";"One carbon pool by folate";"Methane metabolism";"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Photorespiration ";"Folate polyglutamylation";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Folate transformations II (plants)" XP_018904542.1 7 Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-445095 "Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Nephrin family interactions";"Interaction between L1 and Ankyrins" XP_018898009.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018903363.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018915674.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_018902593.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_018908120.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018899233.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018902861.1 6 KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143 "Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis" XP_018907601.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018902305.1 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis" XP_018917022.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_018908148.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_018900332.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_018908000.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_018918010.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_018915131.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" XP_018918100.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_018905298.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018906345.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_018905027.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018902519.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-6799198 "Respiratory electron transport";"Mitochondrial protein import";"Complex I biogenesis" XP_018906517.1 4 Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_018899384.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_018899910.1 22 MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-5353;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7606;MetaCyc: PWY-6433;MetaCyc: PWY-7726;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7728;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7053;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134 "Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation" XP_018916779.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018911161.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018902992.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_018903900.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018910335.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018900676.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_018911476.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_018900755.1 12 Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-381038;Reactome: R-HSA-2132295 "AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes";"MHC class II antigen presentation" XP_018917263.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_018912693.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_018914523.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018903300.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_018916599.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018915119.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_018901127.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_018917063.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_018902678.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_018903654.1 19 Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825 "Chylomicron clearance";"Chylomicron assembly";"LDL remodeling";"Scavenging by Class A Receptors";"Chylomicron remodeling";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"VLDL assembly";"Clathrin-mediated endocytosis";"VLDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis" XP_018901988.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_018899531.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018906820.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018903011.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_018900840.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_018909679.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase" XP_018896827.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018899522.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018912361.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_018904811.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" XP_018910108.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_018907730.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018910671.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants" XP_018908720.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018916368.1 6 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062;Reactome: R-HSA-390247;Reactome: R-HSA-5684045;Reactome: R-HSA-2046105;Reactome: R-HSA-2046106 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis";"Beta-oxidation of very long chain fatty acids";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Linoleic acid (LA) metabolism";"alpha-linolenic acid (ALA) metabolism" XP_018899502.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_018900949.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018915116.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_018901450.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_018913521.1 5 MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-7234 "Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III" XP_018907682.1 12 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"DCC mediated attractive signaling";"mTOR signaling pathway";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Relaxin signaling pathway";"Rho GTPase cycle";"G alpha (12/13) signalling events";"Human cytomegalovirus infection" XP_018909463.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1" XP_018904759.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex" XP_018899536.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181430 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle" XP_018897679.1 2 Reactome: R-HSA-5654726;Reactome: R-HSA-190373 "Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation" XP_018905456.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_018901585.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018908552.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_018905101.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_018913226.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_018908924.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018909031.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_018917055.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_018902386.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_018907063.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763 "MET receptor recycling";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction" XP_018908858.1 13 KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1 "Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism" XP_018914276.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_018909188.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018911140.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial protein import";"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018899646.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018911415.1 9 Reactome: R-HSA-9657050;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-9656255;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-5649702;Reactome: R-HSA-110328 "Defective OGG1 Localization";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Binding";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_018912271.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862 "Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_018913787.1 17 Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-1169091;Reactome: R-HSA-9014325;Reactome: R-HSA-202424;Reactome: R-HSA-9645460;Reactome: R-HSA-5689880;Reactome: R-HSA-975163;Reactome: R-HSA-4086398;Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-937042;Reactome: R-HSA-5357956;Reactome: R-HSA-450302 "CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Activation of NF-kappaB in B cells";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Downstream TCR signaling";"Alpha-protein kinase 1 signaling pathway";"Ub-specific processing proteases";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ca2+ pathway";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation" XP_018912173.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018900236.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018897147.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth" XP_018906834.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018907659.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_018917416.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_018915506.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_018916600.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018914067.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018902768.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_018899997.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018902360.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_018915018.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018903723.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_018896466.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555 "Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Purine metabolism";"PKA activation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events" XP_018918215.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_018913814.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018915067.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018907522.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_018911990.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018909795.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_018912620.1 3 KEGG: 00040+3.1.1.11;MetaCyc: PWY-7248;MetaCyc: PWY-7246 "Pentose and glucuronate interconversions";"Pectin degradation II";"Pectin degradation I" XP_018911381.1 5 KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018897582.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_018917683.1 11 Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400253 "Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock" XP_018902503.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_018906259.1 4 Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788 "SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling" XP_018914715.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" XP_018905270.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_018906592.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018910262.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018907897.1 10 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04926+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Recycling pathway of L1";"Relaxin signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Human cytomegalovirus infection" XP_018900057.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018899562.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018916799.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_018903901.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018913846.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018915966.1 8 Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-196025 "Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions" XP_018905867.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018907342.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018917427.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018904602.1 8 Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750;Reactome: R-HSA-5685942 "HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)" XP_018902679.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018906634.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018915281.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018900026.1 4 Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis" XP_018896397.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018911390.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_018898149.1 10 MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Galactose metabolism";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)" XP_018913864.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018900920.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_018905666.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018912393.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_018902318.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_018907905.1 6 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions" XP_018896469.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Purine metabolism";"PKA activation";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_018910886.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits" XP_018901279.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_018915507.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018903983.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018912560.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_018896358.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018911980.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_018907328.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018907936.1 6 Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_018904756.1 13 Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-437239 "LDL clearance";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1" XP_018895687.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018900316.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Macroautophagy" XP_018914330.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018904024.1 6 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-416993 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors" XP_018913087.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_018901691.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9 "Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_018916359.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_018904250.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_018905462.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_018898017.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_018895928.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_018897191.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_018912295.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_018903730.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_018915453.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_018901026.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_018896543.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_018898209.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_018897557.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_018914378.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_018915289.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_018902114.1 13 MetaCyc: PWY-7198;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_018911405.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018899674.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_018905427.1 3 KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_018910163.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018915997.1 5 KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2 "Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" XP_018907341.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018902924.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" XP_018905610.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_018910339.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018912167.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_018906953.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_018904108.1 6 Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685 "Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Peroxisomal protein import";"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species" XP_018917297.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_018911939.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018905200.1 29 Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-113418 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex" XP_018907038.1 22 Reactome: R-HSA-6798695;MetaCyc: PWY-622;KEGG: 00520+5.3.1.9;MetaCyc: PWY-7385;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-621;MetaCyc: PWY-8013;KEGG: 00010+5.3.1.9;Reactome: R-HSA-5628897;KEGG: 00030+5.3.1.9;MetaCyc: PWY-6981;MetaCyc: PWY-5514;MetaCyc: PWY-5054;MetaCyc: PWY-3801;KEGG: 00500+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-5384;MetaCyc: PWY-7238;MetaCyc: PWY-6992;Reactome: R-HSA-70171;MetaCyc: PWY-5659 "Neutrophil degranulation";"Starch biosynthesis";"Amino sugar and nucleotide sugar metabolism";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Sucrose degradation III (sucrose invertase)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Glycolysis / Gluconeogenesis";"TP53 Regulates Metabolic Genes";"Pentose phosphate pathway";"Chitin biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"D-sorbitol biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Sucrose biosynthesis III";"Sucrose degradation IV (sucrose phosphorylase)";"Sucrose biosynthesis II";"1,5-anhydrofructose degradation";"Glycolysis";"GDP-mannose biosynthesis" XP_018916996.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018902505.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex" XP_018908521.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018914031.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_018901839.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018912407.1 11 Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_018905647.1 7 Reactome: R-HSA-73817;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205;MetaCyc: PWY-6596 "Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Adenosine nucleotides degradation I" XP_018910914.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018913138.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018901777.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_018904178.1 8 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"T cell receptor signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_018913037.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Neutrophil degranulation";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_018897879.1 4 KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716 "Selenocompound metabolism";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_018910042.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_018903204.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_018904703.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_018895896.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018916679.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018917873.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018896090.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018899647.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018910365.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_018897176.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018917804.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018911176.1 11 Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-174430 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand synthesis initiation" XP_018901312.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018908909.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_018907761.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018900975.1 18 Reactome: R-HSA-75105;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5690;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5172 "Fatty acyl-CoA biosynthesis";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Acetyl-coa biosynthesis III (from citrate)" XP_018906911.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018914827.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942 "Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)" XP_018897037.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018907400.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295 "Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"MHC class II antigen presentation" XP_018917791.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018914771.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_018898990.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-428540 "Downstream signal transduction";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Activation of RAC1" XP_018908971.1 3 Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3 "Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism" XP_018916499.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends" XP_018916213.1 12 MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II" XP_018902869.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_018896422.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018909166.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_018896481.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018913315.1 4 Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69202 "Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition" XP_018916894.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_018917735.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis" XP_018906788.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_018907883.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018906855.1 5 Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-936440 "TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling" XP_018901690.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159 "Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling" XP_018914480.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_018913449.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_018906837.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018906112.1 7 MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500 "Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle" XP_018898295.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018900097.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_018903442.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_018901122.1 4 KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines" XP_018917593.1 5 KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;MetaCyc: PWY-5531;Reactome: R-HSA-189451;MetaCyc: PWY-7766 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)" XP_018896926.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018895650.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018914575.1 2 KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_018899765.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-5689880 "Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"Ub-specific processing proteases" XP_018899083.1 179 Reactome: R-HSA-180585;Reactome: R-HSA-156827;Reactome: R-HSA-5362768;Reactome: R-HSA-205043;Reactome: R-HSA-8856828;Reactome: R-HSA-5654727;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-8939902;Reactome: R-HSA-174048;Reactome: R-HSA-382556;Reactome: R-HSA-9615710;Reactome: R-HSA-937039;Reactome: R-HSA-8866652;Reactome: R-HSA-209560;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-2122948;Reactome: R-HSA-68949;Reactome: R-HSA-1253288;Reactome: R-HSA-209543;Reactome: R-HSA-3785653;Reactome: R-HSA-211733;Reactome: R-HSA-8948747;Reactome: R-HSA-72706;Reactome: R-HSA-110312;Reactome: R-HSA-69231;Reactome: R-HSA-5357905;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-1169091;Reactome: R-HSA-5689896;Reactome: R-HSA-5358346;Reactome: R-HSA-2565942;Reactome: R-HSA-901032;Reactome: R-HSA-5684264;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-5675482;Reactome: R-HSA-9020702;Reactome: R-HSA-2979096;Reactome: R-HSA-5689877;Reactome: R-HSA-9613829;Reactome: R-HSA-5610780;Reactome: R-HSA-917937;Reactome: R-HSA-8856825;Reactome: R-HSA-975956;Reactome: R-HSA-8866654;Reactome: R-HSA-162588;Reactome: R-HSA-174084;Reactome: R-HSA-110314;Reactome: R-HSA-975957;Reactome: R-HSA-937041;Reactome: R-HSA-156902;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-936964;Reactome: R-HSA-5678895;Reactome: R-HSA-8876493;Reactome: R-HSA-6804756;Reactome: R-HSA-5654732;Reactome: R-HSA-5654726;Reactome: R-HSA-9645460;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-72764;Reactome: R-HSA-5656121;Reactome: R-HSA-8863795;Reactome: R-HSA-202424;Reactome: R-HSA-977225;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-192823;Reactome: R-HSA-69481;Reactome: R-HSA-975144;Reactome: R-HSA-5676590;Reactome: R-HSA-2408557;Reactome: R-HSA-4641258;Reactome: R-HSA-4641263;Reactome: R-HSA-6782135;Reactome: R-HSA-5205685;Reactome: R-HSA-5607761;Reactome: R-HSA-5357956;Reactome: R-HSA-5696394;Reactome: R-HSA-6804760;Reactome: R-HSA-2173796;Reactome: R-HSA-9033241;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-8852276;Reactome: R-HSA-5655862;Reactome: R-HSA-182971;Reactome: R-HSA-936440;Reactome: R-HSA-8875360;Reactome: R-HSA-9646399;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-6804757;Reactome: R-HSA-9633012;Reactome: R-HSA-3322077;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-1169408;Reactome: R-HSA-174154;Reactome: R-HSA-5696395;Reactome: R-HSA-168928;Reactome: R-HSA-2672351;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-69541;Reactome: R-HSA-1295596;Reactome: R-HSA-6783310;Reactome: R-HSA-3769402;Reactome: R-HSA-450408;Reactome: R-HSA-937072;Reactome: R-HSA-6781827;Reactome: R-HSA-179409;Reactome: R-HSA-349425;Reactome: R-HSA-174490;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-937042;Reactome: R-HSA-9013507;Reactome: R-HSA-6791226;Reactome: R-HSA-5654733;Reactome: R-HSA-532668;Reactome: R-HSA-912631;Reactome: R-HSA-2173795;Reactome: R-HSA-5632684;Reactome: R-HSA-5696400;Reactome: R-HSA-1799339;Reactome: R-HSA-5656169;Reactome: R-HSA-72689;Reactome: R-HSA-6781823;Reactome: R-HSA-450321;Reactome: R-HSA-201681;Reactome: R-HSA-2173791;Reactome: R-HSA-5610785;Reactome: R-HSA-5696397;Reactome: R-HSA-975110;Reactome: R-HSA-975163;Reactome: R-HSA-2173788;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-9013973;Reactome: R-HSA-175474;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-2644606;Reactome: R-HSA-9637628;Reactome: R-HSA-9636383;Reactome: R-HSA-1236382;Reactome: R-HSA-2559582;Reactome: R-HSA-1358803;Reactome: R-HSA-450302;Reactome: R-HSA-5675221;Reactome: R-HSA-2122947;Reactome: R-HSA-69601;Reactome: R-HSA-5693565;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-168927;Reactome: R-HSA-2559585;Reactome: R-HSA-5689901;Reactome: R-HSA-168638;Reactome: R-HSA-8849469;Reactome: R-HSA-3134975;Reactome: R-HSA-9604323;Reactome: R-HSA-110320;Reactome: R-HSA-2691232 "Vif-mediated degradation of APOBEC3G";"L13a-mediated translational silencing of Ceruloplasmin expression";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NRIF signals cell death from the nucleus";"Clathrin-mediated endocytosis";"Negative regulation of FGFR2 signaling";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Cyclin B";"ABC-family proteins mediated transport";"Late endosomal microautophagy";"IRAK1 recruits IKK complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"NF-kB is activated and signals survival";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Activated NOTCH1 Transmits Signal to the Nucleus";"Orc1 removal from chromatin";"Downregulation of ERBB4 signaling";"p75NTR recruits signalling complexes";"Myoclonic epilepsy of Lafora";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN localization";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translesion synthesis by REV1";"Cyclin D associated events in G1";"Regulation of TNFR1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Activation of NF-kappaB in B cells";"Ovarian tumor domain proteases";"Hedgehog ligand biogenesis";"Regulation of PLK1 Activity at G2/M Transition";"ER Quality Control Compartment (ERQC)";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of necroptotic cell death";"Interleukin-1 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Josephin domain DUBs";"Chaperone Mediated Autophagy";"Degradation of GLI1 by the proteasome";"Iron uptake and transport";"Cargo recognition for clathrin-mediated endocytosis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"E3 ubiquitin ligases ubiquitinate target proteins";"Budding and maturation of HIV virion";"Autodegradation of Cdh1 by Cdh1:APC/C";"Recognition of DNA damage by PCNA-containing replication complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"IKK complex recruitment mediated by RIP1";"Peptide chain elongation";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Defective CFTR causes cystic fibrosis";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of TP53 Activity through Phosphorylation";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Alpha-protein kinase 1 signaling pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Eukaryotic Translation Termination";"Translesion synthesis by POLI";"Downregulation of ERBB2 signaling";"Downstream TCR signaling";"Amyloid fiber formation";"Neddylation";"FCERI mediated NF-kB activation";"Viral mRNA Translation";"G2/M Checkpoints";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NIK-->noncanonical NF-kB signaling";"Selenocysteine synthesis";"Degradation of DVL";"Regulation of FZD by ubiquitination";"Dual incision in TC-NER";"Pink/Parkin Mediated Mitophagy";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR1-induced NFkappaB signaling pathway";"DNA Damage Recognition in GG-NER";"Regulation of TP53 Activity through Methylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Peroxisomal protein import";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translesion synthesis by POLK";"EGFR downregulation";"Negative regulators of DDX58/IFIH1 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Aggrephagy";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Degradation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Glycogen synthesis";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"ISG15 antiviral mechanism";"APC/C:Cdc20 mediated degradation of Securin";"Formation of Incision Complex in GG-NER";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Stimuli-sensing channels";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Stabilization of p53";"Spry regulation of FGF signaling";"Fanconi Anemia Pathway";"Deactivation of the beta-catenin transactivating complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of the E3 ubiquitin ligase COP1";"Membrane binding and targetting of GAG proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"IRAK2 mediated activation of TAK1 complex";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol";"Negative regulation of FGFR4 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of signaling by CBL";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Hedgehog 'on' state";"Dual Incision in GG-NER";"SRP-dependent cotranslational protein targeting to membrane";"Termination of translesion DNA synthesis";"Formation of a pool of free 40S subunits";"Formation of TC-NER Pre-Incision Complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TCF dependent signaling in response to WNT";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"GLI3 is processed to GLI3R by the proteasome";"Gap-filling DNA repair synthesis and ligation in GG-NER";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downregulation of TGF-beta receptor signaling";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"TICAM1-dependent activation of IRF3/IRF7";"Assembly Of The HIV Virion";"Separation of Sister Chromatids";"Degradation of AXIN";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Modulation by Mtb of host immune system";"Prevention of phagosomal-lysosomal fusion";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Senescence-Associated Secretory Phenotype (SASP)";"Downregulation of ERBB2:ERBB3 signaling";"activated TAK1 mediates p38 MAPK activation";"Negative regulation of MAPK pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Oncogene Induced Senescence";"Metalloprotease DUBs";"NOD1/2 Signaling Pathway";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of innate immune responses to cytosolic DNA";"Negative regulation of NOTCH4 signaling";"Translesion Synthesis by POLH";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_018904853.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_018914095.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018903311.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018916356.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018904601.1 8 Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-8953750;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_018904600.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018898636.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_018899004.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_018913607.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018898102.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018902788.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018901056.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_018905909.1 7 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis" XP_018906920.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018900051.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018900379.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_018899340.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018901129.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_018916184.1 3 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation" XP_018896460.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_018896784.1 5 Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-75105 "Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis" XP_018904028.1 3 Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588 "Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_018915642.1 11 KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-6992;Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-7586;Reactome: R-HSA-4043916;MetaCyc: PWY-882;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456 "Fructose and mannose metabolism";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation" XP_018907135.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_018909446.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018909691.1 5 Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68867 "Orc1 removal from chromatin";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex" XP_018899175.1 34 Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-69273 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Cyclin A/B1/B2 associated events during G2/M transition" XP_018906889.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018896557.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_018901867.1 5 Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131 "Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"MHC class II antigen presentation";"Collagen degradation";"Trafficking and processing of endosomal TLR" XP_018907893.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_018914274.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_018915447.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018901583.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018905437.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_018899828.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_018905636.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018903266.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_018908230.1 4 Reactome: R-HSA-6787450;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol" XP_018912384.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018912460.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018904654.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_018901782.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_018907180.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_018905309.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949 "Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin" XP_018897565.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018896100.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_018910505.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_018910149.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018914764.1 12 MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-7230;MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;KEGG: 00130+1.14.99.60 "Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_018901653.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_018917703.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018903358.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_018903244.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_018896759.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018916431.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_018896505.1 9 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis" XP_018902026.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_018915667.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_018908358.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_018906048.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018914671.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018910880.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_018912275.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_018915030.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018908571.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_018915729.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_018896887.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_018915639.1 4 KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation" XP_018913835.1 5 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-201722 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex" XP_018905351.1 5 Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5610787 "Activation of SMO";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state" XP_018902942.1 3 MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_018900213.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_018905643.1 58 MetaCyc: PWY-7606;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00360+4.2.1.17;KEGG: 00281+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00627+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;Reactome: R-HSA-77346;MetaCyc: PWY-7401;KEGG: 00592+4.2.1.17;KEGG: 00310+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;Reactome: R-HSA-77350;MetaCyc: PWY-5109;MetaCyc: PWY-7778;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-5138;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;Reactome: R-HSA-77288;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6863;Reactome: R-HSA-77348;MetaCyc: PWY-7007;Reactome: R-HSA-77310;MetaCyc: PWY-7654;MetaCyc: PWY-6946;MetaCyc: PWY-6945;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5177;Reactome: R-HSA-77285;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;Reactome: R-HSA-77305;Reactome: R-HSA-1482798;KEGG: 00280+4.2.1.17;KEGG: 00930+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-7216;KEGG: 00362+4.2.1.17;MetaCyc: PWY-1361;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Benzoate degradation";"Toluene degradation";"Pyruvate fermentation to butanol II (engineered)";"Phenylalanine metabolism";"Geraniol degradation";"Fatty acid elongation";"Fatty acid degradation";"Tryptophan metabolism";"Methyl tert-butyl ether degradation";"Aminobenzoate degradation";"Fatty acid degradation";"Caprolactam degradation";"Spodoptera littoralis pheromone biosynthesis";"Tryptophan metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"alpha-Linolenic acid metabolism";"Lysine degradation";"beta-Alanine metabolism";"Androstenedione degradation";"Valine, leucine and isoleucine degradation";"Carbon fixation pathways in prokaryotes";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fermentation to 2-methylbutanoate";"2-methylpropene degradation";"Butanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Lysine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Carbon fixation pathways in prokaryotes";"Geraniol degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Propanoate metabolism";"Pyruvate fermentation to hexanol (engineered)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Methyl ketone biosynthesis (engineered)";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Limonene and pinene degradation";"Glutaryl-coa degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Fatty acid elongation";"Pyruvate fermentation to butanol I";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Acyl chain remodeling of CL";"Valine, leucine and isoleucine degradation";"Caprolactam degradation";"Fatty acid salvage";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Benzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)" XP_018911007.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" XP_018918115.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018902329.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_018901784.1 3 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation" XP_018913817.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018912335.1 6 Reactome: R-HSA-1655829;Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-381426 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_018908628.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018903430.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_018898482.1 5 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis" XP_018905710.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_018904126.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018903506.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_018899843.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_018909045.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018915984.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins" XP_018899992.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Purine metabolism";"PKA activation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_018917657.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018899608.1 3 Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193 "Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_018895600.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism" XP_018916309.1 5 KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_018911358.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018914314.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_018913264.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018901313.1 3 Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760 "RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation" XP_018900505.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_018912188.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_018908972.1 3 Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3 "Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism" XP_018901432.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_018902671.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_018907922.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018910125.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018912904.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_018905289.1 16 MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-7124;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-2221;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-7218 "Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_018917023.1 11 Reactome: R-HSA-5668599;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.137;KEGG: 04070+2.7.1.137;MetaCyc: PWY-6352;Reactome: R-HSA-168138;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1632852;Reactome: R-HSA-1660517;Reactome: R-HSA-109704 "RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Macroautophagy";"Synthesis of PIPs at the late endosome membrane";"PI3K Cascade" XP_018917860.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_018899341.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018909085.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018907506.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_018914692.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_018916778.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018906943.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_018917471.1 4 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism" XP_018917241.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression" XP_018896236.1 3 Reactome: R-HSA-2206291;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096 "MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation";"HS-GAG degradation" XP_018916042.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_018902324.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_018908392.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_018902673.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_018914323.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_018906050.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018895836.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018909175.1 2 KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841 "Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation" XP_018901856.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_018909302.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_018915083.1 11 Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135 "Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER" XP_018898313.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_018909407.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_018910956.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018901655.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_018903961.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018899826.1 18 MetaCyc: PWY-7115;MetaCyc: PWY-5690;KEGG: 00630+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7383;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-1622;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Glyoxylate and dicarboxylate metabolism";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" XP_018916651.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_018914917.1 15 Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348 "Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex" XP_018900963.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_018899472.1 3 Reactome: R-HSA-6787639;Reactome: R-HSA-5619078;Reactome: R-HSA-727802 "GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars" XP_018899273.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018908925.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018897326.1 3 KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686 "Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I" XP_018917237.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_018908660.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018906505.1 24 Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-163359;Reactome: R-HSA-416482;Reactome: R-HSA-418592;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-500657 "ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Glucagon signaling in metabolic regulation";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 1";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"Ca2+ pathway";"G-protein activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors" XP_018896239.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018909104.1 13 MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-6859;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-7709;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141 "Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis" XP_018906418.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018906135.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018901363.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_018915177.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_018902495.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018906198.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_018902452.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_018916777.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018916962.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_018896021.1 12 KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13 "Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism" XP_018917412.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_018908977.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_018902708.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018900498.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_018899832.1 14 Reactome: R-HSA-3769402;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-450520;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-5687128;Reactome: R-HSA-9648025 "Deactivation of the beta-catenin transactivating complex";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"HuR (ELAVL1) binds and stabilizes mRNA";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"MAPK6/MAPK4 signaling";"EML4 and NUDC in mitotic spindle formation" XP_018898309.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018903263.1 30 Reactome: R-HSA-5696400;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-2564830;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-674695 "Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events" XP_018896760.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018916489.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_018898374.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018896453.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018912391.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_018902013.1 5 Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638 "VEGFA-VEGFR2 Pathway";"p38MAPK events";"DSCAM interactions";"mTOR signaling pathway";"NOD1/2 Signaling Pathway" XP_018912485.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018905363.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_018897743.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018911375.1 29 Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-77075 "RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE" XP_018909574.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018904768.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_018912224.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018898969.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131 "Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Collagen degradation";"Trafficking and processing of endosomal TLR" XP_018900378.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_018913074.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018909440.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018898429.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018910730.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018906110.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815 "Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones" XP_018913816.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018915967.1 8 Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-432720 "Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis" XP_018898025.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_018897712.1 3 Reactome: R-HSA-9645722;Reactome: R-HSA-111471;Reactome: R-HSA-140837 "Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation" XP_018896753.1 5 Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558 "Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" XP_018898594.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_018902266.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape" XP_018902332.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_018907698.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_018895617.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_018903040.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018897973.1 10 MetaCyc: PWY-5484;MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-7003;KEGG: 00051+5.3.1.1;MetaCyc: PWY-6142;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70171 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Glycolysis" XP_018899845.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018916321.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018900933.1 56 Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174154 "Activation of NF-kappaB in B cells";"Neddylation";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin" XP_018914612.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_018905651.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_018906673.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_018910499.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018900916.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_018897144.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_018896499.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_018910735.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_018907896.1 10 KEGG: 04926+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human cytomegalovirus infection";"RSK activation";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_018903190.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018898175.1 5 KEGG: 00280+1.2.4.4;Reactome: R-HSA-389661;Reactome: R-HSA-70895;MetaCyc: PWY-5046;KEGG: 00640+1.2.4.4 "Valine, leucine and isoleucine degradation";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Propanoate metabolism" XP_018914430.1 6 MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17 "Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway" XP_018914954.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018900276.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018898620.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018904451.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018902925.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_018917816.1 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_018915445.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-179409 "APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A" XP_018903528.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018914301.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_018911734.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018915480.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018906333.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_018917600.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018915797.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_018895891.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018914656.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_018912680.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187 "Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress" XP_018903075.1 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" XP_018911100.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018912703.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018909837.1 13 Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52 "CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation" XP_018907923.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_018909346.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018911540.1 2 KEGG: 00780+2.8.1.6;MetaCyc: PWY-7380 "Biotin metabolism";"Biotin biosynthesis from 8-amino-7-oxononanoate II" XP_018908342.1 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" XP_018912851.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018906964.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_018899814.1 14 Reactome: R-HSA-70895;MetaCyc: PWY-5076;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5108;KEGG: 00270+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5104;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5101 "Branched-chain amino acid catabolism";"L-leucine degradation III";"Glucosinolate biosynthesis";"L-valine degradation II";"L-isoleucine biosynthesis V";"Cysteine and methionine metabolism";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Pantothenate and CoA biosynthesis";"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis II" XP_018914870.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018915033.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018914763.1 12 MetaCyc: PWY-5857;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-7233;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-6708 "Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_018896839.1 5 KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3 "Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)" XP_018899777.1 4 Reactome: R-HSA-189483;MetaCyc: PWY-5874;KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937 "Heme degradation";"Heme degradation I";"Porphyrin and chlorophyll metabolism";"Iron uptake and transport" XP_018898903.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_018895893.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018914275.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_018899989.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040 "Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Purine metabolism";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_018902863.1 6 Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952 "Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_018913818.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018897699.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018913314.1 4 Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202 "Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition" XP_018900197.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760 "PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation" XP_018913656.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_018918073.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_018901244.1 13 MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-8052;Reactome: R-HSA-6785470;MetaCyc: PWY-7286;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-8868766;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-6787450 "Trna methylation (yeast)";"Methylwyosine biosynthesis";"2-arachidonoylglycerol biosynthesis";"tRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"rRNA processing in the mitochondrion";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"tRNA modification in the mitochondrion" XP_018912523.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_018909088.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018903046.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018902554.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_018908478.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018900714.1 10 Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation" XP_018902442.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_018909612.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_018898596.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018901916.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018906699.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018896092.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_018901654.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_018913837.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018902132.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018909708.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018898906.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018903526.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_018906926.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_018912621.1 3 KEGG: 00040+3.1.1.11;MetaCyc: PWY-7248;MetaCyc: PWY-7246 "Pentose and glucuronate interconversions";"Pectin degradation II";"Pectin degradation I" XP_018906510.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018897648.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_018917900.1 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_018902504.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_018901827.1 6 Reactome: R-HSA-2173788;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Circadian Clock";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018910927.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_018913657.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_018903607.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_018898534.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-2586552 "Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling";"Signaling by Leptin" XP_018917382.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_018910360.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_018908758.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018904027.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018908243.1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I" XP_018908391.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_018913047.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018901081.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018914530.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018909176.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852 "Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy" XP_018896390.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_018918128.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018915762.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_018904603.1 8 Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_018895656.1 21 KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7198;MetaCyc: PWY-7219;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7184;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.6+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7222 "Purine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_018910168.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018896720.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_018916412.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_018897229.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_018899633.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_018917455.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018896939.1 1 KEGG: 00230+3.6.1.3 "Purine metabolism" XP_018900748.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018896185.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598 "Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis" XP_018902687.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_018900444.1 12 KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-7901;MetaCyc: PWY-6936;MetaCyc: PWY-6309;MetaCyc: PWY-2821;MetaCyc: PWY-801;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;MetaCyc: PWY-1187 "Selenocompound metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from homomethionine" XP_018918091.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018899337.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018912287.1 24 Reactome: R-HSA-163560;Reactome: R-HSA-432040;Reactome: R-HSA-5610785;KEGG: 04150+2.7.11.11;Reactome: R-HSA-381676;Reactome: R-HSA-9634600;Reactome: R-HSA-5687128;Reactome: R-HSA-4420097;Reactome: R-HSA-392517;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-5621575;Reactome: R-HSA-422356;Reactome: R-HSA-163615;Reactome: R-HSA-8853659;Reactome: R-HSA-983231;Reactome: R-HSA-111931;Reactome: R-HSA-442720;Reactome: R-HSA-8963896;Reactome: R-HSA-180024;Reactome: R-HSA-9010642;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-163358 "Triglyceride catabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"GLI3 is processed to GLI3R by the proteasome";"mTOR signaling pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"MAPK6/MAPK4 signaling";"VEGFA-VEGFR2 Pathway";"Rap1 signalling";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"CD209 (DC-SIGN) signaling";"Regulation of insulin secretion";"PKA activation";"RET signaling";"Factors involved in megakaryocyte development and platelet production";"PKA-mediated phosphorylation of CREB";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"HDL assembly";"DARPP-32 events";"ROBO receptors bind AKAP5";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"PKA-mediated phosphorylation of key metabolic factors" XP_018915798.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_018909857.1 3 Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300 "HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors" XP_018914260.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_018898289.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018902480.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018913158.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_018911486.1 4 KEGG: 00410+4.1.1.9;Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241 "beta-Alanine metabolism";"Beta-oxidation of very long chain fatty acids";"Propanoate metabolism";"Peroxisomal protein import" XP_018915708.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_018897462.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_018905494.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018902010.1 5 Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24 "DSCAM interactions";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"mTOR signaling pathway" XP_018899537.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_018914149.1 6 MetaCyc: PWY-5744;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5743 "Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"3-hydroxypropanoate cycle" XP_018908195.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018895711.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)" XP_018896140.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_018901991.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_018908366.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_018899908.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_018911943.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_018899080.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_018897872.1 52 Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-73776;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-167290;Reactome: R-HSA-6803529;Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-76071;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-76061;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-112382 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Promoter Escape";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of HIV elongation";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"HIV Transcription Initiation";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex" XP_018911091.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018908242.1 4 KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_018905792.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_018897819.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018910652.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_018900566.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018915460.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018906550.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy" XP_018900058.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018909409.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018910724.1 2 Reactome: R-HSA-114608;Reactome: R-HSA-2132295 "Platelet degranulation";"MHC class II antigen presentation" XP_018917857.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_018902489.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018897465.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_018909888.1 6 KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17 "Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation";"Ascorbate and aldarate metabolism" XP_018904079.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_018904489.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018916918.1 12 Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-399719 "Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"NrCAM interactions";"Long-term potentiation";"Purine metabolism";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors" XP_018906925.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_018915672.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_018916224.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018907256.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_018918243.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018899861.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_018914164.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_018907727.1 7 Reactome: R-HSA-2160456;MetaCyc: PWY-7158;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;Reactome: R-HSA-8964208 "Phenylketonuria";"L-phenylalanine degradation V";"Folate biosynthesis";"L-tyrosine biosynthesis IV";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism" XP_018911353.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018896593.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_018917979.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_018900717.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018917769.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_018899457.1 12 MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-3801;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Glycerolipid metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Galactose metabolism" XP_018916823.1 2 Reactome: R-HSA-2559584;Reactome: R-HSA-3214847 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)";"HATs acetylate histones" XP_018912251.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_018904254.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_018911666.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_018910548.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_018900317.1 5 Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-1632852 "TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"Macroautophagy" XP_018905093.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_018901316.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018914266.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_018914573.1 1 Reactome: R-HSA-419771 "Opsins" XP_018907401.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131 "MHC class II antigen presentation";"Collagen degradation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR" XP_018911516.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_018908728.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_018903540.1 18 MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166 "Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Synthesis of PA" XP_018902097.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_018915893.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_018905278.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_018904154.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018917061.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I" XP_018900173.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_018906932.1 3 KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation" XP_018904319.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_018908816.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_018914200.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358752 "AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated" XP_018917026.1 2 Reactome: R-HSA-5173105;Reactome: R-HSA-5083628 "O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_018917591.1 5 MetaCyc: PWY-5514;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-6855 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Chitin degradation I (archaea)" XP_018917091.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_018897073.1 52 Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-113418;Reactome: R-HSA-76066;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-5601884;Reactome: R-HSA-5250924;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-73779;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-76071;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-76061;Reactome: R-HSA-674695;Reactome: R-HSA-1834949 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA" XP_018918220.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018905489.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_018908911.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_018909129.1 7 Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472 "HCMV Early Events";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_018916167.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018913834.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018914474.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_018901584.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018918103.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018899632.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_018915921.1 18 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;Reactome: R-HSA-5689901;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-3108214;Reactome: R-HSA-8953750;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;MetaCyc: PWY-7511;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-1221632;Reactome: R-HSA-6804756 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Metalloprotease DUBs";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of DNA damage response and repair proteins";"Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Protein ubiquitination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Meiotic synapsis";"Regulation of TP53 Activity through Phosphorylation" XP_018900360.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018910707.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018913462.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_018911095.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018911534.1 7 MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-7282;Reactome: R-HSA-73817 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" XP_018905659.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018898254.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_018905576.1 5 KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-7761 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)" XP_018900944.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018917066.1 10 MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2 "4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Cyanoamino acid metabolism" XP_018907021.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_018916403.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_018916731.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_018904091.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_018908468.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018905689.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism" XP_018916650.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_018897186.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_018914782.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_018907851.1 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" XP_018913509.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018907079.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018904653.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018904056.1 19 Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901 "Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"LDL clearance";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Chylomicron assembly";"Scavenging by Class A Receptors";"LDL remodeling";"Chylomicron remodeling" XP_018898825.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_018917507.1 13 Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5 "Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes" XP_018906074.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_018898418.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018899123.1 11 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-69231;Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"Cyclin D associated events in G1";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_018897207.1 3 Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases" XP_018915183.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_018904766.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018910349.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018906921.1 20 Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-5696397 "Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_018903663.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_018913059.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018906159.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018901768.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018914657.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_018914040.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_018898437.1 5 Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.64;KEGG: 04070+3.1.3.64;MetaCyc: PWY-6580;MetaCyc: PWY-6368 "Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation" XP_018901650.1 4 MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26 "Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate" XP_018916452.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_018914923.1 15 Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-5467333;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348 "Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants are not K63 polyubiquitinated";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex" XP_018901917.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852 "Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy" XP_018909269.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018908629.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018904706.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-389357 "Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling" XP_018896244.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018915649.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_018917172.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018908853.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_018900383.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018906098.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018914423.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018909264.1 5 MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2 "L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism" XP_018917616.1 32 Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-168325;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-167238 "Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation" XP_018917170.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018911306.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_018911414.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_018897659.1 3 Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis" XP_018901918.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852 "Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy" XP_018903609.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018906353.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_018909966.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_018913833.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018914421.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018918151.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018901647.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria" XP_018909964.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_018902927.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_018895659.1 21 MetaCyc: PWY-7205;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7219;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7187 "CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_018909342.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018899455.1 12 KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801 "Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycogen synthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Stachyose degradation";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)" XP_018904788.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_018907515.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018907735.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_018913891.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018899383.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_018918011.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_018906899.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018898540.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_018916141.1 12 Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells" XP_018909742.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_018898595.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_018901396.1 52 Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902 "NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity" XP_018912947.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018901581.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018897390.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018904023.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_018899381.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_018910448.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_018913252.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018900967.1 3 MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12 "Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism" XP_018908984.1 57 Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-68949 "Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Neutrophil degranulation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Orc1 removal from chromatin" XP_018900389.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_018900893.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_018916771.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018905386.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_018914739.1 17 KEGG: 04660+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167287;KEGG: 05235+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-167243;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-75955 "T cell receptor signaling pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation" XP_018902795.1 6 Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383;Reactome: R-HSA-6798695 "Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"HS-GAG degradation";"Other glycan degradation";"Lysosomal oligosaccharide catabolism";"Neutrophil degranulation" XP_018902891.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_018904868.1 7 Reactome: R-HSA-1483226;MetaCyc: PWY-7625;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11 "Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system" XP_018912095.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018918090.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018911449.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER" XP_018912401.1 27 Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-975957;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-159227;Reactome: R-HSA-975956;Reactome: R-HSA-113418;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159236;Reactome: R-HSA-674695;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-9010553;Reactome: R-HSA-72203;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-73856;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-6803529 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"Transport of the SLBP independent Mature mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the Early Elongation Complex";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Pre-transcription Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Regulation of expression of SLITs and ROBOs";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Termination";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing" XP_018916540.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_018914833.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_018897318.1 9 Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy";"Neutrophil degranulation";"mTOR signalling";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" XP_018914304.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_018904529.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" XP_018914889.1 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis" XP_018910913.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018901137.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018899891.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_018901716.1 4 MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22 "Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism" XP_018898057.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018900695.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_018912909.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_018898652.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018896375.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_018915989.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" XP_018900554.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018909482.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7 "Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis" XP_018904088.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018906901.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018909785.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018907900.1 8 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018896376.1 40 Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-5578749;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-168325;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529 "Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"Viral Messenger RNA Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing" XP_018896802.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_018916653.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018897790.1 8 Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Ion channel transport";"Insulin receptor recycling";"Photosynthesis";"Transferrin endocytosis and recycling" XP_018899385.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_018905453.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018914023.1 17 Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-1221632;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 04151+2.7.11.1 "Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Meiotic synapsis";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Thermogenesis";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"PI3K-Akt signaling pathway" XP_018896081.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_018910315.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018898517.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7411 "Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)" XP_018901139.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_018905091.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_018912728.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018908927.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_018913646.1 15 Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459 "Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_018912466.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018908409.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_018913844.1 7 KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25 "Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phytate degradation I";"Streptomycin biosynthesis" XP_018917057.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_018903129.1 3 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis" XP_018904500.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_018898373.1 3 MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9 "Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_018897894.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-5628897 "Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes" XP_018908923.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061 "Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I" XP_018914613.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_018898678.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_018902181.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_018904809.1 5 Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565 "Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_018907876.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_018900193.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018902260.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656 "Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling" XP_018905290.1 16 KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-5723;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-7124;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-6886;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-6901 "Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation" XP_018913222.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-113501 "Removal of the Flap Intermediate";"Polymerase switching";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" XP_018912333.1 7 Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531 "MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus" XP_018900124.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018896613.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018900412.1 2 KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" XP_018905584.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_018902421.1 6 MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1 "Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_018898515.1 10 KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051 "Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I" XP_018903567.1 17 Reactome: R-HSA-3371599;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-196780;Reactome: R-HSA-163765;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1 "Defective HLCS causes multiple carboxylase deficiency";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Jadomycin biosynthesis";"Fatty acid biosynthesis";"Carnitine metabolism";"Pyruvate metabolism";"Glyoxylate assimilation";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)" XP_018915804.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_018908670.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_018899309.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_018915803.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_018917506.1 13 MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5 "Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism" XP_018912098.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018903785.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018904613.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_018898346.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_018898314.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_018895597.1 4 KEGG: 00770+2.1.2.11;KEGG: 00770+6.3.2.1;MetaCyc: PWY-6654;KEGG: 00410+6.3.2.1 "Pantothenate and CoA biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis III (archaebacteria)";"beta-Alanine metabolism" XP_018903301.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_018909976.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168 "Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)" XP_018906440.1 3 Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_018912903.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-156711 "G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Polo-like kinase mediated events" XP_018912539.1 4 MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87 "Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis" XP_018896635.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018905104.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_018916394.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_018906256.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018916902.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_018897640.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018915664.1 5 KEGG: 00140+1.3.1.22;MetaCyc: PWY-7455;MetaCyc: PWY-6032;KEGG: 00905+1.3.1.22;Reactome: R-HSA-193048 "Steroid hormone biosynthesis";"Allopregnanolone biosynthesis";"Digitoxigenin biosynthesis";"Brassinosteroid biosynthesis";"Androgen biosynthesis" XP_018908132.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131 "Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR" XP_018914167.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_018917493.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_018914817.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040 "Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"PKA activation";"G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_018912725.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018903560.1 17 KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6722;Reactome: R-HSA-3371599;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-163765;MetaCyc: PWY-5789 "Pyruvate metabolism";"Carnitine metabolism";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Glyoxylate assimilation";"Candicidin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Aflatoxin biosynthesis";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_018915500.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018911284.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018916914.1 8 Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Purine metabolism";"RAF/MAP kinase cascade" XP_018905546.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_018896612.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018914451.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018916095.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_018913302.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_018916935.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018896673.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_018902018.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_018896116.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018914930.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_018906429.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180585 "Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G" XP_018917142.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_018897036.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018905161.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress" XP_018904476.1 4 KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism" XP_018900096.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_018917166.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018901640.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018913644.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" XP_018905622.1 18 Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-6807505 "RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes" XP_018910859.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_018910965.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018903278.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_018917338.1 14 MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7411 "CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)" XP_018911040.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_018903956.1 5 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling" XP_018916804.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018898744.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018905475.1 18 MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839 "Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE" XP_018910394.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018917245.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018917782.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_018899118.1 5 Reactome: R-HSA-392154;Reactome: R-HSA-1222556;MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39 "Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"Arginine biosynthesis" XP_018903216.1 11 MetaCyc: PWY-381;Reactome: R-HSA-210455;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2 "Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Arginine biosynthesis" XP_018903595.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_018895595.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018898055.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_018909805.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018905133.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_018906626.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_018907296.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001 "Neutrophil degranulation";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Sialic acid metabolism" XP_018908841.1 15 Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes" XP_018902758.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018911928.1 13 MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913 "Methylaspartate cycle";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)" XP_018898967.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_018918045.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018911126.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018911518.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018903213.1 11 KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-381;MetaCyc: PWY-6549;Reactome: R-HSA-210455 "Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism" XP_018896830.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_018906490.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018908095.1 12 Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;MetaCyc: PWY-7901;MetaCyc: PWY-6842;KEGG: 00450+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-801;MetaCyc: PWY-2821;MetaCyc: PWY-6936;MetaCyc: PWY-6309 "Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Glucosinolate biosynthesis from tyrosine";"Glutathione-mediated detoxification II";"Selenocompound metabolism";"Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)" XP_018900117.1 4 Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-166058 "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" XP_018907149.1 5 Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880 "Regulation of PTEN stability and activity";"Protein ubiquitination";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases" XP_018899235.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_018896765.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105 "Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis" XP_018912354.1 10 Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483 "Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs" XP_018908128.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018911167.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_018897226.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_018912945.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018900315.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8854214 "Macroautophagy";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs" XP_018913379.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_018911105.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_018903563.1 17 KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-163765;Reactome: R-HSA-196780 "Fatty acid biosynthesis";"Carnitine metabolism";"Pyruvate metabolism";"Glyoxylate assimilation";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism" XP_018904081.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_018895906.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018902524.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_018904322.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018897926.1 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_018906516.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_018914428.1 5 KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_018896073.1 10 MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-4041 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle" XP_018905095.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_018901030.1 15 Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693565 "G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_018913348.1 13 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation" XP_018898076.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018903020.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018912855.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_018900809.1 56 Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-69481 "Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"G2/M Checkpoints" XP_018904382.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018911070.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375280 "G alpha (q) signalling events";"Amine ligand-binding receptors" XP_018899157.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_018914861.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018902067.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018896077.1 10 MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13 "Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism" XP_018914759.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_018916218.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_018900362.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-937072 "MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_018896610.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018915254.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018916380.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018910721.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_018905130.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018901597.1 18 KEGG: 00400+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1 "Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Sulfolactate degradation III";"Arginine and proline metabolism" XP_018905226.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018914429.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018909881.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018906261.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_018908480.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018915982.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1" XP_018914506.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018900860.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018902134.1 4 MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4 "Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_018916026.1 7 Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-983231;Reactome: R-HSA-8943724;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519 "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Factors involved in megakaryocyte development and platelet production";"Regulation of PTEN gene transcription";"HDMs demethylate histones";"Estrogen-dependent gene expression" XP_018896888.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-264870;Reactome: R-HSA-6798695 "Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation" XP_018916648.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_018905703.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018917077.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_018898255.1 10 MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-7344;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism" XP_018912854.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_018918265.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018895984.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018910649.1 15 Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167152 "Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat" XP_018915698.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018908380.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_018903310.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018917007.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_018901773.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_018897939.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_018911461.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018917715.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_018912481.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_018910092.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187 "Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing" XP_018906956.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_018898613.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018905551.1 13 KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1 "Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism" XP_018902338.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018915514.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018915934.1 7 Reactome: R-HSA-5658034;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5362798 "HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state";"Activation of SMO";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Release of Hh-Np from the secreting cell" XP_018915511.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_018916506.1 11 Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-2173796;Reactome: R-HSA-72163;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"mRNA Splicing - Major Pathway";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_018907511.1 3 Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)" XP_018897133.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_018910276.1 5 Reactome: R-HSA-9630221;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-9630222 "Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding" XP_018899174.1 34 Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-69273;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-167246;Reactome: R-HSA-113418 "TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex" XP_018914479.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_018895575.1 14 Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5696397 "Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Polymerase switching";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_018896186.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619 "Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis" XP_018902676.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_018910396.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018915089.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_018898123.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018903332.1 3 KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100;Reactome: R-HSA-71262 "Lysine degradation";"L-carnitine biosynthesis";"Carnitine synthesis" XP_018908341.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018910167.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018900363.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041 "Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1" XP_018908067.1 5 Reactome: R-HSA-901032;Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-381038 "ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes" XP_018904812.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_018912025.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018910866.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_018897426.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018903202.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_018915969.1 8 Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells" XP_018906574.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018899520.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018907879.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_018896449.1 3 MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9 "Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis" XP_018913217.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018911343.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_018905245.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018909646.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_018917944.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018898653.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018897927.1 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_018897618.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018903140.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018915587.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409 "Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis" XP_018900558.1 6 Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-139915 "Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria" XP_018916588.1 3 KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_018900331.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_018897868.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018905509.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_018908390.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_018908121.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018903149.1 2 Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "Formation of apoptosome";"Regulation of the apoptosome activity" XP_018915641.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018904950.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018917410.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_018914727.1 3 Reactome: R-HSA-5694530;Reactome: R-HSA-948021;Reactome: R-HSA-204005 "Cargo concentration in the ER";"Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport" XP_018898542.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257 "G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN" XP_018908385.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism" XP_018910082.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_018906365.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018900144.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_018911157.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018911222.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_018900409.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_018914263.1 52 Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-76071;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-6803529;Reactome: R-HSA-5601884;Reactome: R-HSA-5250924;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-113418;Reactome: R-HSA-5617472 "TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"FGFR2 alternative splicing";"PIWI-interacting RNA (piRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_018908958.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018914168.1 1 MetaCyc: PWY-6938 "NADH repair" XP_018915763.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_018916263.1 57 Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764 "SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling" XP_018910812.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_018911555.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018903233.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018905272.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018908401.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_018902509.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_018900704.1 2 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_018913832.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018916571.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018904725.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018902862.1 6 KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143 "Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis" XP_018909224.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018915663.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_018912624.1 3 KEGG: 00040+3.1.1.11;MetaCyc: PWY-7248;MetaCyc: PWY-7246 "Pentose and glucuronate interconversions";"Pectin degradation II";"Pectin degradation I" XP_018905631.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276 "Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Degradation of AXIN";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Neddylation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_018904512.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018901914.1 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_018903130.1 3 Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11 "Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" XP_018901121.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_018903733.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_018909089.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-2132295 "Antigen processing: Ubiquitination & Proteasome degradation";"MHC class II antigen presentation" XP_018910081.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_018914389.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_018898453.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_018899684.1 15 Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700 "Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_018905623.1 18 Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-167242 "Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_018908993.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018914277.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_018902930.1 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" XP_018899446.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_018900181.1 7 Reactome: R-HSA-192456;Reactome: R-HSA-1912420;Reactome: R-HSA-975634;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-350054 "Digestion of dietary lipid";"Pre-NOTCH Processing in Golgi";"Retinoid metabolism and transport";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway" XP_018897461.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_018903597.1 8 Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5173105 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation" XP_018907983.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_018903114.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_018916500.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_018913775.1 8 Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210 "Regulation of TP53 Degradation";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_018901649.1 14 Reactome: R-HSA-5620924;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-1632852;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Intraflagellar transport";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Macroautophagy";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_018902447.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_018907720.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018910482.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018906590.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018916085.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_018907102.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_018917990.1 7 KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514;MetaCyc: PWY-8004;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-6906;Reactome: R-HSA-71336 "Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Entner-Doudoroff pathway I";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Pentose phosphate pathway" XP_018903479.1 17 Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-176187;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8953750;Reactome: R-HSA-69601;Reactome: R-HSA-75035;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-1433557 "Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Activation of ATR in response to replication stress";"Human cytomegalovirus infection";"G2/M DNA damage checkpoint";"Thermogenesis";"mTOR signaling pathway";"Transcriptional Regulation by E2F6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"Processing of DNA double-strand break ends";"Signaling by SCF-KIT" XP_018908676.1 17 Reactome: R-HSA-1169091;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325;Reactome: R-HSA-202424;Reactome: R-HSA-168638;Reactome: R-HSA-4086398;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-450321 "Activation of NF-kappaB in B cells";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Downstream TCR signaling";"NOD1/2 Signaling Pathway";"Ca2+ pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_018902428.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_018904919.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018903612.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_018899575.1 7 Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-8043;MetaCyc: PWY-7255 "Glutathione synthesis and recycling";"Glutathione metabolism";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)" XP_018910423.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_018915444.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018910209.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018915602.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018901713.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_018900943.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018897255.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_018905497.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-983231 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production" XP_018913126.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_018914576.1 2 KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_018914403.1 13 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"mTOR signalling";"Regulation of PTEN gene transcription";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy" XP_018915408.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018918230.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018903352.1 11 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"p38MAPK events";"mTOR signaling pathway";"Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection" XP_018906012.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018917029.1 2 Reactome: R-HSA-5173105;Reactome: R-HSA-5083628 "O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_018896078.1 10 MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-4041 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle" XP_018906538.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018904511.1 14 Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519 "MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression" XP_018912805.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_018917103.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_018901336.1 14 Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-674695 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events" XP_018901830.1 6 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018905381.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" XP_018900384.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018915697.1 11 Reactome: R-HSA-5693571;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3270619;Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Nonhomologous End-Joining (NHEJ)";"Relaxin signaling pathway";"IRF3-mediated induction of type I IFN";"E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection";"Cytosolic sensors of pathogen-associated DNA";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_018914321.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018909457.1 7 Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946 "Estrogen-dependent gene expression";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_018914202.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_018896059.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557 "Translation initiation complex formation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis" XP_018905065.1 13 Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-419037;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-216083;Reactome: R-HSA-1442490;Reactome: R-HSA-186797;Reactome: R-HSA-3000157;Reactome: R-HSA-1650814;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090 "ECM proteoglycans";"Collagen chain trimerization";"NCAM1 interactions";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Integrin cell surface interactions";"Collagen degradation";"Signaling by PDGF";"Laminin interactions";"Collagen biosynthesis and modifying enzymes";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures" XP_018898817.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_018899143.1 9 MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5744 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation" XP_018910681.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018896203.1 3 Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018910643.1 12 Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-166208;Reactome: R-HSA-9010553 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs" XP_018898462.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018914322.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018914436.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689896 "Ub-specific processing proteases";"Ovarian tumor domain proteases" XP_018911019.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_018917790.1 2 KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199 "N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate" XP_018908833.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018913654.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_018907892.1 10 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Relaxin signaling pathway";"Recycling pathway of L1";"Human cytomegalovirus infection";"RSK activation" XP_018905393.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_018916313.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_018898570.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_018912123.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)" XP_018902926.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_018899705.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018898104.1 10 Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042 "Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)" XP_018899925.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_018916780.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018903142.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018912394.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_018898604.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018904249.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018915495.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018912935.1 5 Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391 "Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)" XP_018910704.1 8 MetaCyc: PWY-6901;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-8086;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268 "Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism" XP_018915000.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018902341.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_018899957.1 5 KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" YP_086803.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018914348.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_018902661.1 5 KEGG: 00650+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4 "Butanoate metabolism";"Mevalonate degradation";"Synthesis and degradation of ketone bodies";"Geraniol degradation";"Valine, leucine and isoleucine degradation" XP_018896779.1 5 Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-75105 "Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis" XP_018912206.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_018917931.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018901090.1 13 Reactome: R-HSA-416572;Reactome: R-HSA-3928663;Reactome: R-HSA-5627117;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1 "Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"RHO GTPases Activate ROCKs";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"EPHB-mediated forward signaling";"mTOR signaling pathway" XP_018906140.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018917173.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018904193.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018903309.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018912102.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018905495.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018898660.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018909793.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_018910614.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_018916630.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018902793.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_018916381.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018914756.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_018899112.1 1 Reactome: R-HSA-201451 "Signaling by BMP" XP_018915927.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018901385.1 27 Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_018907762.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_018910065.1 6 Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-5632927 "Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH3" XP_018900329.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_018913612.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_018914770.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_018909195.1 5 Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_018906320.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_018899577.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_018898251.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway" XP_018908168.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018900364.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade" XP_018904484.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018909278.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018899857.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_018895738.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis" XP_018897184.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_018896892.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018912534.1 4 Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-9020702 "IRAK1 recruits IKK complex";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling" XP_018905366.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018909998.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018908122.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018895629.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174 "Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_018914879.1 13 KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662 "Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism" XP_018897230.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_018918257.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018916079.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_018916572.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018916681.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_018918235.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_018897145.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade" XP_018916826.1 5 Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749 "Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I" XP_018912355.1 10 Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852 "Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy" XP_018902030.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018899224.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018904478.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_018918042.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_018910673.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946 "Platelet degranulation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants" XP_018909202.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_018895889.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018906982.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018902184.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_018906513.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" XP_018912686.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_018908705.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018906587.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_018912640.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_018901449.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_018898933.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490 "Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Collagen degradation" XP_018904337.1 12 KEGG: 00630+6.4.1.3;MetaCyc: PWY-5743;MetaCyc: PWY-7384;KEGG: 00720+6.4.1.3;Reactome: R-HSA-196780;Reactome: R-HSA-71032;MetaCyc: PWY-5789;MetaCyc: PWYG-321;KEGG: 00640+6.4.1.3;MetaCyc: PWY-6728;Reactome: R-HSA-3371599;KEGG: 00280+6.4.1.3 "Glyoxylate and dicarboxylate metabolism";"3-hydroxypropanoate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Propionyl-CoA catabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"";"Propanoate metabolism";"Methylaspartate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Valine, leucine and isoleucine degradation" XP_018903993.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018912328.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_018897272.1 12 MetaCyc: PWY-5856;MetaCyc: PWY-6978;MetaCyc: PWY-5857;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;Reactome: R-HSA-1268020;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5871;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870 "Ubiquinol-9 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)" XP_018909614.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_018911094.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018898988.1 5 Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131 "Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"MHC class II antigen presentation";"Collagen degradation";"Trafficking and processing of endosomal TLR" XP_018908582.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_018905593.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" XP_018895939.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_018913531.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018897395.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018906132.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018899855.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_018916272.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_018899853.1 15 Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756 "Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation" XP_018906089.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_018912667.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_018896728.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_018903357.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_018915302.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_018912089.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_018902382.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_018899812.1 14 MetaCyc: PWY-5076;Reactome: R-HSA-70895;MetaCyc: PWY-5057;MetaCyc: PWY-5108;KEGG: 00966+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-7767;MetaCyc: PWY-5103;KEGG: 00770+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5078 "L-leucine degradation III";"Branched-chain amino acid catabolism";"L-valine degradation II";"L-isoleucine biosynthesis V";"Glucosinolate biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis III";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine degradation";"L-isoleucine degradation II" XP_018898516.1 10 MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7411 "Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)" XP_018898257.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_018901626.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018917997.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018908486.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_018909345.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018910013.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018903731.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_018902015.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_018909180.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_018910879.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_018916961.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_018913433.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_018897273.1 12 Reactome: R-HSA-1268020;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5871;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-6978;MetaCyc: PWY-5857;MetaCyc: PWY-5872;Reactome: R-HSA-2142789 "Mitochondrial protein import";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis" XP_018917128.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018916135.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018910343.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018910127.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_018896410.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018917627.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_018915098.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018897307.1 8 MetaCyc: PWY-7115;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-5743 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle" XP_018912706.1 8 Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Blockage of phagosome acidification";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_018897463.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_018916895.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_018907913.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_018903259.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018900143.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_018895883.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018917078.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_018904262.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_018896461.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_018911265.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_018896840.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018914860.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing" XP_018899935.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Amino acids regulate mTORC1" XP_018904679.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827 "Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex" XP_018907989.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic" XP_018905517.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_018912387.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_018912467.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901441.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018911385.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_018897091.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_018906624.1 7 Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases";"UCH proteinases";"DNA Damage Recognition in GG-NER";"Telomere Extension By Telomerase";"HATs acetylate histones" XP_018901938.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018904485.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018912026.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018911592.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018916176.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_018907728.1 7 Reactome: R-HSA-2160456;MetaCyc: PWY-7158;KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00360+1.14.16.1;Reactome: R-HSA-8964208 "Phenylketonuria";"L-phenylalanine degradation V";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Phenylalanine metabolism" XP_018915253.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018911012.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018909529.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018900812.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7445 "Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation" XP_018917247.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018912232.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018909898.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_018897275.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_018906551.1 1 KEGG: 00780+2.6.1.62 "Biotin metabolism" XP_018913213.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018912858.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_018906147.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018910099.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018916859.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018916858.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_018897151.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018896624.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018896512.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_018906952.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_018907536.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018906832.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018901106.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490 "Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"MHC class II antigen presentation";"Collagen degradation" XP_018897569.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018916568.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018902254.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828 "MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis" XP_018902304.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis" XP_018917498.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_018900333.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_018901682.1 1 Reactome: R-HSA-419771 "Opsins" XP_018908836.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_018905212.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_018903542.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_018898900.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018912483.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_018911564.1 8 Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556 "Nef Mediated CD8 Down-regulation";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes" XP_018898966.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_018898463.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_018898785.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_018908879.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_018904017.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018896889.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827 "Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex" XP_018905154.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes" XP_018909668.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018898626.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_018903505.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_018902283.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018913776.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_018900839.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_018913121.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018904026.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination" XP_018904326.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018901783.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_018910171.1 6 KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-6908 "Thiamine metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)" XP_018903132.1 3 KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis" XP_018899444.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_018903016.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_018904937.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018902449.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_018913722.1 5 Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922 "Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Activation of SMO";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium" XP_018906518.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_018914251.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_018904246.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018911264.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_018909138.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018903022.1 10 Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-2197563;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-350054 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway" XP_018915166.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018896391.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_018914412.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018904161.1 5 Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_018900404.1 3 KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9 "Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate" XP_018899091.1 4 Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37 "DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism" XP_018900359.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_018900008.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_018895945.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018906907.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018908698.1 6 Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216 "MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization" XP_018905142.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018906260.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-191859 "tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly" XP_018907906.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_018907504.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_018904596.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_018902859.1 6 KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_018901873.1 25 Reactome: R-HSA-8949275;Reactome: R-HSA-8941284;Reactome: R-HSA-8940973;Reactome: R-HSA-8939245;Reactome: R-HSA-8939247;Reactome: R-HSA-8939256;Reactome: R-HSA-8939246;Reactome: R-HSA-9616222;Reactome: R-HSA-8939243;Reactome: R-HSA-8877330;Reactome: R-HSA-8934593;Reactome: R-HSA-8941333;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8941326;Reactome: R-HSA-8931987;Reactome: R-HSA-8951936;Reactome: R-HSA-8941858;Reactome: R-HSA-8935964;Reactome: R-HSA-8939242;Reactome: R-HSA-8941332;Reactome: R-HSA-8951911;Reactome: R-HSA-8939236 "RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"RUNX2 regulates bone development";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX3 regulates p14-ARF";"Regulation of RUNX3 expression and activity";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates genes involved in cell migration";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_018898904.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018916598.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018908024.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_018896195.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813 "Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids" XP_018911774.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018898404.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_018914553.1 13 KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2160916 "Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation" XP_018916276.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018912671.1 9 Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783 "A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type" XP_018917884.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_018905667.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018902684.1 2 Reactome: R-HSA-442660;Reactome: R-HSA-352230 "Na+/Cl- dependent neurotransmitter transporters";"Amino acid transport across the plasma membrane" XP_018897264.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_018916828.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_018910358.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018908204.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_018904595.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_018903631.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018897891.1 5 Reactome: R-HSA-6798695;KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;Reactome: R-HSA-71336;MetaCyc: PWY-8060 "Neutrophil degranulation";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I" XP_018910258.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018912245.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_018900431.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs" XP_018909204.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018903291.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018915755.1 10 Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_018911050.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_018901276.1 3 Reactome: R-HSA-983231;Reactome: R-HSA-383280;Reactome: R-HSA-8939236 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_018900209.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_018904983.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_018905295.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_018913178.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018902479.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_018909594.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_018916773.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018914813.1 14 Reactome: R-HSA-4419969;MetaCyc: PWY-8053;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-7782 "Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Synthesis of PE";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Synthesis of PC";"Triglyceride biosynthesis";"Plasmalogen biosynthesis" XP_018903366.1 10 Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-76042 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_018910455.1 1 MetaCyc: PWY-6938 "NADH repair" XP_018911261.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018908353.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_018910435.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_018899956.1 3 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_018917802.1 5 Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16 "Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018898465.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes" XP_018896023.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_018909490.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_018896484.1 3 MetaCyc: PWY-5694;MetaCyc: PWY-5705;KEGG: 00230+4.3.2.3 "Allantoin degradation to glyoxylate I";"Allantoin degradation to glyoxylate III";"Purine metabolism" XP_018908053.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_018902989.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-380972 "Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_018901696.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_018902517.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018899149.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_018909794.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_018904573.1 6 MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143 "Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis" XP_018917402.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_018900515.1 7 KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00330+2.5.1.22 "Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism" XP_018899581.1 6 MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12 "Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis" XP_018914337.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_018907915.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_018896433.1 3 Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-2151201 "HATs acetylate histones";"UCH proteinases";"Transcriptional activation of mitochondrial biogenesis" XP_018901831.1 6 KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018902939.1 4 KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_018917781.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_018903905.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018916677.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018902980.1 66 Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-176412;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-2559582;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-5610785;Reactome: R-HSA-176407;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-179409;Reactome: R-HSA-1169091;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-141430;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695 "Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Phosphorylation of the APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Degradation of AXIN";"Separation of Sister Chromatids";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Neddylation";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"GLI3 is processed to GLI3R by the proteasome";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"APC-Cdc20 mediated degradation of Nek2A";"Activation of NF-kappaB in B cells";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Neutrophil degranulation" XP_018906632.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_018900430.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)" XP_018906686.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_018895834.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_018916680.1 3 KEGG: 00300+5.1.1.7;MetaCyc: PWY-2941;MetaCyc: PWY-5097 "Lysine biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis VI" XP_018904416.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_018914492.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_018909473.1 2 Reactome: R-HSA-8950505;Reactome: R-HSA-8937144 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Aryl hydrocarbon receptor signalling" XP_018901155.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_018914365.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018907334.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018911477.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_018910596.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018900719.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018903957.1 5 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018910922.1 57 Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601 "CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Neddylation";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" XP_018914755.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_018913122.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_018911792.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" XP_018909098.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events" XP_018899615.1 7 MetaCyc: PWY-3561;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039 "Choline biosynthesis III";"Synthesis of PG";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Synthesis of PA";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_018903899.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018918258.1 8 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_018915586.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018912363.1 182 Reactome: R-HSA-72689;Reactome: R-HSA-5656169;Reactome: R-HSA-1799339;Reactome: R-HSA-5696400;Reactome: R-HSA-5632684;Reactome: R-HSA-2173791;Reactome: R-HSA-201681;Reactome: R-HSA-975163;Reactome: R-HSA-2173788;Reactome: R-HSA-975110;Reactome: R-HSA-5696397;Reactome: R-HSA-5610785;Reactome: R-HSA-6781823;Reactome: R-HSA-450321;Reactome: R-HSA-175474;Reactome: R-HSA-9013973;Reactome: R-HSA-2559582;Reactome: R-HSA-9636383;Reactome: R-HSA-1236382;Reactome: R-HSA-9637628;Reactome: R-HSA-2644606;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-8849469;Reactome: R-HSA-5689901;Reactome: R-HSA-168638;Reactome: R-HSA-2559585;Reactome: R-HSA-9010553;Reactome: R-HSA-168927;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-2691232;Reactome: R-HSA-110320;Reactome: R-HSA-3134975;Reactome: R-HSA-450302;Reactome: R-HSA-72695;Reactome: R-HSA-1358803;Reactome: R-HSA-69601;Reactome: R-HSA-5693565;Reactome: R-HSA-2122947;Reactome: R-HSA-5675221;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-9646399;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-182971;Reactome: R-HSA-8852276;Reactome: R-HSA-936440;Reactome: R-HSA-8875360;Reactome: R-HSA-2672351;Reactome: R-HSA-168928;Reactome: R-HSA-5696395;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-6804757;Reactome: R-HSA-1169408;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-9633012;Reactome: R-HSA-3322077;Reactome: R-HSA-179409;Reactome: R-HSA-6781827;Reactome: R-HSA-937072;Reactome: R-HSA-72649;Reactome: R-HSA-174490;Reactome: R-HSA-349425;Reactome: R-HSA-1295596;Reactome: R-HSA-6783310;Reactome: R-HSA-5610783;Reactome: R-HSA-69541;Reactome: R-HSA-450408;Reactome: R-HSA-3769402;Reactome: R-HSA-9013507;Reactome: R-HSA-912631;Reactome: R-HSA-2173795;Reactome: R-HSA-532668;Reactome: R-HSA-6791226;Reactome: R-HSA-5654733;Reactome: R-HSA-983168;Reactome: R-HSA-937042;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-975957;Reactome: R-HSA-937041;Reactome: R-HSA-400253;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-8856825;Reactome: R-HSA-5610780;Reactome: R-HSA-917937;Reactome: R-HSA-110314;Reactome: R-HSA-174084;Reactome: R-HSA-162588;Reactome: R-HSA-8866654;Reactome: R-HSA-8876493;Reactome: R-HSA-2894862;Reactome: R-HSA-5678895;Reactome: R-HSA-936964;Reactome: R-HSA-69481;Reactome: R-HSA-192823;Reactome: R-HSA-2871837;Reactome: R-HSA-977225;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-975144;Reactome: R-HSA-8854050;Reactome: R-HSA-5654726;Reactome: R-HSA-9645460;Reactome: R-HSA-5654732;Reactome: R-HSA-6804756;Reactome: R-HSA-8863795;Reactome: R-HSA-202424;Reactome: R-HSA-5656121;Reactome: R-HSA-72764;Reactome: R-HSA-68827;Reactome: R-HSA-9033241;Reactome: R-HSA-2173796;Reactome: R-HSA-6804760;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-8939236;Reactome: R-HSA-4641263;Reactome: R-HSA-4641258;Reactome: R-HSA-2408557;Reactome: R-HSA-5607761;Reactome: R-HSA-5357956;Reactome: R-HSA-5696394;Reactome: R-HSA-5205685;Reactome: R-HSA-6782135;Reactome: R-HSA-205043;Reactome: R-HSA-8856828;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-156827;Reactome: R-HSA-75815;Reactome: R-HSA-8866652;Reactome: R-HSA-209560;Reactome: R-HSA-937039;Reactome: R-HSA-2122948;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-917729;Reactome: R-HSA-6807004;Reactome: R-HSA-5654727;Reactome: R-HSA-9615710;Reactome: R-HSA-382556;Reactome: R-HSA-174048;Reactome: R-HSA-5358346;Reactome: R-HSA-5689896;Reactome: R-HSA-445989;Reactome: R-HSA-1169091;Reactome: R-HSA-901032;Reactome: R-HSA-2565942;Reactome: R-HSA-209543;Reactome: R-HSA-3785653;Reactome: R-HSA-1253288;Reactome: R-HSA-68949;Reactome: R-HSA-5357905;Reactome: R-HSA-9014325;Reactome: R-HSA-110312;Reactome: R-HSA-69231;Reactome: R-HSA-72706;Reactome: R-HSA-8948747;Reactome: R-HSA-211733;Reactome: R-HSA-5689877;Reactome: R-HSA-2979096;Reactome: R-HSA-72702;Reactome: R-HSA-9613829;Reactome: R-HSA-1236974;Reactome: R-HSA-5684264;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5675482;Reactome: R-HSA-174178 "Formation of a pool of free 40S subunits";"Termination of translesion DNA synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Dual Incision in GG-NER";"Hedgehog 'on' state";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TCF dependent signaling in response to WNT";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downregulation of TGF-beta receptor signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Gap-filling DNA repair synthesis and ligation in GG-NER";"GLI3 is processed to GLI3R by the proteasome";"Formation of TC-NER Pre-Incision Complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Assembly Of The HIV Virion";"TICAM1-dependent activation of IRF3/IRF7";"Senescence-Associated Secretory Phenotype (SASP)";"Prevention of phagosomal-lysosomal fusion";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Modulation by Mtb of host immune system";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of AXIN";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Metalloprotease DUBs";"NOD1/2 Signaling Pathway";"Oncogene Induced Senescence";"Regulation of expression of SLITs and ROBOs";"TICAM1, RIP1-mediated IKK complex recruitment";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Translesion Synthesis by POLH";"Regulation of innate immune responses to cytosolic DNA";"activated TAK1 mediates p38 MAPK activation";"Formation of the ternary complex, and subsequently, the 43S complex";"Downregulation of ERBB2:ERBB3 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulation of MAPK pathway";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Aggrephagy";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"EGFR downregulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulators of DDX58/IFIH1 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Stimuli-sensing channels";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Formation of Incision Complex in GG-NER";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Regulation of TP53 Degradation";"ISG15 antiviral mechanism";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Glycogen synthesis";"APC-Cdc20 mediated degradation of Nek2A";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Translation initiation complex formation";"Membrane binding and targetting of GAG proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"Spry regulation of FGF signaling";"Fanconi Anemia Pathway";"Degradation of GLI2 by the proteasome";"Stabilization of p53";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deactivation of the beta-catenin transactivating complex";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulation of signaling by CBL";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Major pathway of rRNA processing in the nucleolus and cytosol";"Negative regulation of FGFR4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"IRAK2 mediated activation of TAK1 complex";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"IKK complex recruitment mediated by RIP1";"Circadian Clock";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Cargo recognition for clathrin-mediated endocytosis";"Degradation of GLI1 by the proteasome";"Iron uptake and transport";"Recognition of DNA damage by PCNA-containing replication complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Budding and maturation of HIV virion";"E3 ubiquitin ligases ubiquitinate target proteins";"InlA-mediated entry of Listeria monocytogenes into host cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Defective CFTR causes cystic fibrosis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"G2/M Checkpoints";"Viral mRNA Translation";"FCERI mediated NF-kB activation";"Amyloid fiber formation";"Neddylation";"NIK-->noncanonical NF-kB signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of FGFR1 signaling";"Alpha-protein kinase 1 signaling pathway";"Negative regulation of FGFR3 signaling";"Regulation of TP53 Activity through Phosphorylation";"Downregulation of ERBB2 signaling";"Downstream TCR signaling";"Translesion synthesis by POLI";"Eukaryotic Translation Termination";"CDT1 association with the CDC6:ORC:origin complex";"Peroxisomal protein import";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of TP53 Activity through Methylation";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of FZD by ubiquitination";"Degradation of DVL";"Selenocysteine synthesis";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR1-induced NFkappaB signaling pathway";"DNA Damage Recognition in GG-NER";"Pink/Parkin Mediated Mitophagy";"Dual incision in TC-NER";"NRIF signals cell death from the nucleus";"Clathrin-mediated endocytosis";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ubiquitin-dependent degradation of Cyclin D";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"NF-kB is activated and signals survival";"IRAK1 recruits IKK complex";"Activated NOTCH1 Transmits Signal to the Nucleus";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity";"Negative regulation of FGFR2 signaling";"Late endosomal microautophagy";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Cyclin B";"Hedgehog ligand biogenesis";"Ovarian tumor domain proteases";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Activation of NF-kappaB in B cells";"ER Quality Control Compartment (ERQC)";"Regulation of PLK1 Activity at G2/M Transition";"p75NTR recruits signalling complexes";"Myoclonic epilepsy of Lafora";"Downregulation of ERBB4 signaling";"Orc1 removal from chromatin";"Regulation of TNFR1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Translesion synthesis by REV1";"Cyclin D associated events in G1";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of PTEN localization";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Josephin domain DUBs";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Ribosomal scanning and start codon recognition";"Chaperone Mediated Autophagy";"ER-Phagosome pathway";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Regulation of necroptotic cell death";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_018913265.1 3 KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709 "N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins" XP_018897385.1 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" XP_018909619.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_018913512.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018905997.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018909043.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018900761.1 57 Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590 "Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling" XP_018911317.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_018911123.1 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_018899462.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_018911475.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_018914240.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_018917686.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_018917967.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_018899345.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_018895829.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018896520.1 7 Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_018904938.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_018911133.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018914379.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes" XP_018913123.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_018900130.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018903037.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018913173.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018910984.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA" XP_018902402.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018917598.1 15 Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-6807505 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes" XP_018908386.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_018908289.1 6 MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599 "UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate" XP_018916494.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_018901708.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018902827.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018912085.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018904673.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_018910870.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018917707.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_018899272.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901658.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_018907916.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_018902343.1 5 Reactome: R-HSA-1482883;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20 "Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis" XP_018917400.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_018896609.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018915501.1 4 Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3;Reactome: R-HSA-6798695;Reactome: R-HSA-2162123 "Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism";"Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)" XP_018904984.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_018908516.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018896498.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_018912332.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_018898766.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_018896232.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_018906277.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_018899985.1 5 Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131 "Collagen degradation";"MHC class II antigen presentation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR" XP_018898408.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_018903913.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_018915214.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_018907409.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018908419.1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" XP_018906072.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_018910924.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_018911407.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949 "Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin" XP_018899586.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018908239.1 4 KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_018909517.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_018896891.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018915448.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_018902623.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_018900675.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_018913690.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_018901093.1 10 MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7411 "CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)" XP_018902278.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018896191.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_018899240.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_018914781.1 8 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5269;KEGG: 05235+3.1.3.16;MetaCyc: PWY-5668;KEGG: 00564+3.1.3.27;MetaCyc: PWY-7817;Reactome: R-HSA-1483148 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Cardiolipin biosynthesis II";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG" XP_018911820.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" XP_018912859.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018906729.1 3 Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129 "Sphingolipid de novo biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)" XP_018917417.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_018916913.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism" XP_018915433.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_018910911.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018915250.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018912857.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018897773.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018899864.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_018909260.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018902590.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018913843.1 7 Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25 "Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Phytate degradation I";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Inositol phosphate metabolism" XP_018897069.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018906622.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_018908378.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018905017.1 2 KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26 "Starch and sucrose metabolism";"Galactose metabolism" XP_018901302.1 26 Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657;Reactome: R-HSA-9018519;Reactome: R-HSA-5621575;Reactome: R-HSA-9013695;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-2644606;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-201722 "Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes";"Estrogen-dependent gene expression";"CD209 (DC-SIGN) signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Circadian Clock";"Attenuation phase";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex" XP_018905577.1 5 MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-5381 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)" XP_018899454.1 12 Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9 "Glycogen synthesis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_018905561.1 13 MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_018898301.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901193.1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" XP_018897861.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018915943.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" XP_018905092.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_018911252.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901929.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018914179.1 3 KEGG: 00040+3.1.1.11;MetaCyc: PWY-7246;MetaCyc: PWY-7248 "Pentose and glucuronate interconversions";"Pectin degradation I";"Pectin degradation II" XP_018902775.1 15 MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6886 "Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Rubisco shunt";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)" XP_018897082.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_018908658.1 13 Reactome: R-HSA-9649948;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 05170+2.7.11.1 "Signaling downstream of RAS mutants";"Human cytomegalovirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Relaxin signaling pathway";"Signaling by high-kinase activity BRAF mutants";"mTOR signaling pathway";"Thermogenesis";"Signaling by moderate kinase activity BRAF mutants";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Signaling by BRAF and RAF fusions";"Human immunodeficiency virus 1 infection" XP_018897231.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_018896670.1 7 Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-2173796 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_018903910.1 4 Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919 "Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Crosslinking of collagen fibrils" XP_018917889.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018917175.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018906548.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018912170.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_018901808.1 30 KEGG: 05163+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-5628897;Reactome: R-HSA-8876198;Reactome: R-HSA-6804758;Reactome: R-HSA-211163;Reactome: R-HSA-111447;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69656;Reactome: R-HSA-9614399;Reactome: R-HSA-199418;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-198693;Reactome: R-HSA-5218920;Reactome: R-HSA-8948751;Reactome: R-HSA-392451;Reactome: R-HSA-1358803;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-9634638;Reactome: R-HSA-6804759;Reactome: R-HSA-389513;Reactome: R-HSA-389357;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8941332;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400 "Human cytomegalovirus infection";"Cyclin E associated events during G1/S transition";"TP53 Regulates Metabolic Genes";"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TP53 Activity through Acetylation";"AKT-mediated inactivation of FOXO1A";"Activation of BAD and translocation to mitochondria";"Relaxin signaling pathway";"mTOR signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of localization of FOXO transcription factors";"Negative regulation of the PI3K/AKT network";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"AKT phosphorylates targets in the nucleus";"VEGFR2 mediated vascular permeability";"Regulation of PTEN stability and activity";"G beta:gamma signalling through PI3Kgamma";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of TP53 Activity through Association with Co-factors";"CTLA4 inhibitory signaling";"CD28 dependent PI3K/Akt signaling";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"RUNX2 regulates genes involved in cell migration";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer" XP_018900972.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_018905488.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_018911997.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_018906498.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_018900525.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_018896680.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_018912010.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" YP_086806.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018903055.1 7 KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7219;KEGG: 00250+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-7234 "Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III" XP_018915070.1 42 Reactome: R-HSA-606279;Reactome: R-HSA-73772;Reactome: R-HSA-5693571;Reactome: R-HSA-3214842;Reactome: R-HSA-5625886;Reactome: R-HSA-3214841;Reactome: R-HSA-3214858;Reactome: R-HSA-9616222;Reactome: R-HSA-110329;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-69473;Reactome: R-HSA-2559582;Reactome: R-HSA-171306;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-8939236;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-5617472;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-73728;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-4551638 "Deposition of new CENPA-containing nucleosomes at the centromere";"RNA Polymerase I Promoter Escape";"Nonhomologous End-Joining (NHEJ)";"HDMs demethylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PKMTs methylate histone lysines";"RMTs methylate histone arginines";"Transcriptional regulation of granulopoiesis";"Cleavage of the damaged pyrimidine";"HCMV Early Events";"PRC2 methylates histones and DNA";"Amyloid fiber formation";"G2/M DNA damage checkpoint";"Senescence-Associated Secretory Phenotype (SASP)";"Packaging Of Telomere Ends";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"DNA methylation";"RNA Polymerase I Promoter Opening";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"SUMOylation of chromatin organization proteins" XP_018896800.1 3 KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_018910164.1 12 Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948 "Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_018906258.1 4 Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356 "Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_018900883.1 5 MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817 "CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_018918134.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018903759.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_018905067.1 31 Reactome: R-HSA-2426168;MetaCyc: PWY-6282;MetaCyc: PWY-5994;MetaCyc: PWY-6799;MetaCyc: PWY-5147;MetaCyc: PWY-5142;MetaCyc: PWY-5367;MetaCyc: PWY-8047;MetaCyc: PWY-5971;MetaCyc: PWY-5966-1;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-7664;Reactome: R-HSA-163765;MetaCyc: PWY-5973;MetaCyc: PWY-8012;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7746;Reactome: R-HSA-9029558;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-6113;Reactome: R-HSA-199220;MetaCyc: PWY-7858;MetaCyc: PWY-6519;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-4381 "Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis I (plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"Cis-vaccenate biosynthesis";"Mupirocin biosynthesis";"Biotin metabolism";"Mycobacterial sulfolipid biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (bacteria and plants)" XP_018917045.1 11 Reactome: R-HSA-983712;Reactome: R-HSA-5663213;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-2029482;Reactome: R-HSA-917977;Reactome: R-HSA-4420097;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Ion channel transport";"RHO GTPases Activate WASPs and WAVEs";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Regulation of actin dynamics for phagocytic cup formation";"Transferrin endocytosis and recycling";"VEGFA-VEGFR2 Pathway";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" XP_018910679.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018902696.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018916130.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_018906343.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_018915965.1 8 Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-432720 "Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis" XP_018906262.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018903892.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_018914065.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018899162.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_018912806.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_018914103.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_018917609.1 2 Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_018907168.1 57 Reactome: R-HSA-8939902;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813 "Regulation of RUNX2 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Neutrophil degranulation";"ER-Phagosome pathway";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids" XP_018896316.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018903863.1 52 Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-5250924;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-6803529;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-76061;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-76071;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-72086 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"B-WICH complex positively regulates rRNA expression";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"FGFR2 alternative splicing";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping" XP_018897564.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018916916.1 12 Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-5673001 "Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"Purine metabolism";"Long-term potentiation";"NrCAM interactions";"RAF/MAP kinase cascade" XP_018900954.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018917926.1 6 Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017 "Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"Tryptophan metabolism";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_018904318.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018896485.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_018909082.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_018909271.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_018911413.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_018912176.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018917675.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018916230.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-176407 "Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_018896970.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018907903.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-176407 "Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_018912662.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_018905108.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_018902662.1 5 KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4 "Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Geraniol degradation";"Valine, leucine and isoleucine degradation" XP_018904870.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604 "VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling" XP_018915933.1 7 Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5362798 "HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Hedgehog 'on' state";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Release of Hh-Np from the secreting cell" XP_018902216.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_018909697.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018899092.1 4 KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118 "Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation" XP_018905592.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HCMV Early Events";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_018911536.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_018895623.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018895700.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_018905665.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018902530.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_018904444.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_018897978.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018897243.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I" XP_018903573.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018908376.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018915673.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_018898431.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_018912151.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018917984.1 6 MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1 "Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" XP_018895898.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018912318.1 11 Reactome: R-HSA-912694;Reactome: R-HSA-389948;Reactome: R-HSA-388841;Reactome: R-HSA-432142;Reactome: R-HSA-114604;Reactome: R-HSA-9008059;Reactome: R-HSA-210990;Reactome: R-HSA-391160;Reactome: R-HSA-877312;Reactome: R-HSA-909733;Reactome: R-HSA-512988 "Regulation of IFNA signaling";"PD-1 signaling";"Costimulation by the CD28 family";"Platelet sensitization by LDL";"GPVI-mediated activation cascade";"Interleukin-37 signaling";"PECAM1 interactions";"Signal regulatory protein family interactions";"Regulation of IFNG signaling";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling" XP_018898274.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018918268.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_018898586.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018909337.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018910716.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018896315.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-114608 "MHC class II antigen presentation";"Platelet degranulation" XP_018898690.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_018899218.1 44 Reactome: R-HSA-879415;Reactome: R-HSA-9649948;Reactome: R-HSA-5654726;Reactome: R-HSA-1295596;Reactome: R-HSA-5654732;Reactome: R-HSA-5674135;Reactome: R-HSA-170968;Reactome: R-HSA-2559582;Reactome: R-HSA-5674499;Reactome: R-HSA-6802946;Reactome: R-HSA-8943724;Reactome: R-HSA-5675221;Reactome: R-HSA-9635465;Reactome: R-HSA-375165;Reactome: R-HSA-6811558;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-198753;Reactome: R-HSA-445144;Reactome: R-HSA-5654733;Reactome: R-HSA-2871796;Reactome: R-HSA-6802952;Reactome: R-HSA-2559585;Reactome: R-HSA-8940973;Reactome: R-HSA-3371453;Reactome: R-HSA-444257;Reactome: R-HSA-5668599;Reactome: R-HSA-6802955;Reactome: R-HSA-9627069;Reactome: R-HSA-5663213;Reactome: R-HSA-112409;Reactome: R-HSA-6802948;Reactome: R-HSA-162658;Reactome: R-HSA-881907;Reactome: R-HSA-74749;Reactome: R-HSA-450341;Reactome: R-HSA-8939211;Reactome: R-HSA-2029482;Reactome: R-HSA-9634638;Reactome: R-HSA-5654727;Reactome: R-HSA-202670;Reactome: R-HSA-5673001;Reactome: R-HSA-456926;Reactome: R-HSA-982772 "Advanced glycosylation endproduct receptor signaling";"Signaling downstream of RAS mutants";"Negative regulation of FGFR1 signaling";"Spry regulation of FGF signaling";"Negative regulation of FGFR3 signaling";"MAP2K and MAPK activation";"Frs2-mediated activation";"Senescence-Associated Secretory Phenotype (SASP)";"Negative feedback regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants";"Regulation of PTEN gene transcription";"Negative regulation of MAPK pathway";"Suppression of apoptosis";"NCAM signaling for neurite out-growth";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"ERK/MAPK targets";"Signal transduction by L1";"Negative regulation of FGFR4 signaling";"FCERI mediated MAPK activation";"Signaling by BRAF and RAF fusions";"Oncogene Induced Senescence";"RUNX2 regulates osteoblast differentiation";"Regulation of HSF1-mediated heat shock response";"RSK activation";"RHO GTPases Activate NADPH Oxidases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of the apoptosome activity";"RHO GTPases Activate WASPs and WAVEs";"RAF-independent MAPK1/3 activation";"Signaling by high-kinase activity BRAF mutants";"Golgi Cisternae Pericentriolar Stack Reorganization";"Gastrin-CREB signalling pathway via PKC and MAPK";"Signal attenuation";"Activation of the AP-1 family of transcription factors";"ESR-mediated signaling";"Regulation of actin dynamics for phagocytic cup formation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Negative regulation of FGFR2 signaling";"ERKs are inactivated";"RAF/MAP kinase cascade";"Thrombin signalling through proteinase activated receptors (PARs)";"Growth hormone receptor signaling" XP_018913150.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018900832.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018915492.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018915184.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018896851.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913061.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018900587.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018903163.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018913899.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-111367 "RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs" XP_018896751.1 31 MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-5994;MetaCyc: PWY-6282;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-8049;MetaCyc: PWY-7746;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-9029558;MetaCyc: PWY-5973;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-7664;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-7858;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-7723 "Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Activation of gene expression by SREBF (SREBP)";"";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Pederin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Biotin metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Cis-vaccenate biosynthesis";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence" XP_018914400.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_018905594.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_018898783.1 5 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" XP_018914829.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" XP_018902794.1 10 KEGG: 04151+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 04150+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04070+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05170+2.7.1.153;MetaCyc: PWY-6352 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane";"Human immunodeficiency virus 1 infection";"3-phosphoinositide biosynthesis" XP_018899521.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018901115.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_018902335.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases" XP_018907872.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_018910301.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018911951.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018914189.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018904569.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018907042.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-399997 "G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion" XP_018915404.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018909502.1 3 Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence" XP_018900986.1 12 Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4 "Transport and synthesis of PAPS";"Sulfur metabolism";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Selenocompound metabolism";"Monobactam biosynthesis";"Sulfite oxidation III";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Purine metabolism" XP_018897984.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018907839.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_018899937.1 8 Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556 "Nef Mediated CD8 Down-regulation";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes" XP_018916919.1 12 Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-442982 "Long-term potentiation";"Purine metabolism";"NrCAM interactions";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor" XP_018904572.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018916958.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_018916860.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018911097.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018898773.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018897006.1 3 Reactome: R-HSA-1442490;Reactome: R-HSA-1474228;Reactome: R-HSA-1592389 "Collagen degradation";"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases" XP_018913069.1 8 Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-4551638 "PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"HCMV Early Events";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins" XP_018899775.1 4 KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937;MetaCyc: PWY-5874;Reactome: R-HSA-189483 "Porphyrin and chlorophyll metabolism";"Iron uptake and transport";"Heme degradation I";"Heme degradation" XP_018897524.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_018899380.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_018910361.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation" XP_018905512.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-432040 "PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_018916171.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_018908929.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_018910915.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018913655.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_018903510.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_018912705.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_018905068.1 13 Reactome: R-HSA-419037;Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-3000171 "NCAM1 interactions";"ECM proteoglycans";"Collagen chain trimerization";"Extracellular matrix organization";"Laminin interactions";"Signaling by PDGF";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions" XP_018914128.1 4 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_018907557.1 4 MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_018909696.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018912179.1 3 MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695 "Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation" XP_018898441.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_018905573.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_018916734.1 10 Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_018910547.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_018901187.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_018905144.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018899778.1 4 Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483;MetaCyc: PWY-5874 "Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation";"Heme degradation I" XP_018910345.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018906568.1 20 Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-6837 "Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" XP_018895830.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway" XP_018898684.1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane" XP_018909897.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_018901364.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_018900531.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-2151201;Reactome: R-HSA-8862803;MetaCyc: PWY-6854;Reactome: R-HSA-8950505;Reactome: R-HSA-3299685 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Transcriptional activation of mitochondrial biogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Detoxification of Reactive Oxygen Species" XP_018905646.1 7 KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596;KEGG: 00230+1.1.1.205;MetaCyc: PWY-7221;Reactome: R-HSA-73817;MetaCyc: PWY-5695;Reactome: R-HSA-6798695 "Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Neutrophil degranulation" XP_018917167.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018899427.1 5 Reactome: R-HSA-111458;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "Formation of apoptosome";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_018904723.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018906497.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_018906931.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_018906104.1 7 Reactome: R-HSA-8856828;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855183 "Clathrin-mediated endocytosis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol" XP_018895783.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018901147.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_018908865.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018912051.1 5 Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-2426168 "Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)" XP_018917830.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_018899540.1 8 Reactome: R-HSA-5173105;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629 "O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_018917927.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_018914787.1 5 Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921 "Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation" XP_018898243.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_018913207.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289 "Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation" XP_018914449.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_018910529.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection" XP_018908096.1 12 MetaCyc: PWY-2821;MetaCyc: PWY-801;MetaCyc: PWY-601;MetaCyc: PWY-6309;MetaCyc: PWY-6936;MetaCyc: PWY-7901;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13 "Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tyrosine";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Tryptophan catabolism";"Cysteine and methionine metabolism" XP_018913474.1 15 Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-9603505 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"NTRK3 as a dependence receptor" XP_018912029.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_018917145.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_018902557.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_018917866.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018900999.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-983168 "Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018905216.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_018909672.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018917381.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_018903351.1 3 Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" XP_018905650.1 6 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway" XP_018903151.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_018917337.1 14 MetaCyc: PWY-7782;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-7589 "Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)" XP_018909137.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_018905107.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_018901245.1 19 MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;Reactome: R-HSA-380270;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;Reactome: R-HSA-380320;MetaCyc: PWY-7221 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Recruitment of NuMA to mitotic centrosomes";"Guanosine ribonucleotides de novo biosynthesis" XP_018906018.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018900153.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_018896016.1 12 MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_018901677.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018903272.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018897409.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex" XP_018910172.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_018901538.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_018909778.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_018912205.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_018901108.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090 "Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Collagen degradation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures" XP_018899124.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018914074.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383 "Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation" XP_018898293.1 6 MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-4261 "Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerol degradation I" XP_018916139.1 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_018913224.1 52 Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-6803529;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-5250924;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-76066 "Signaling by FGFR2 IIIa TM";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"FGFR2 alternative splicing";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"B-WICH complex positively regulates rRNA expression";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_018911182.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_018908388.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_018906636.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018903010.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_018911255.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018915983.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970 "Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1" XP_018904968.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_018916487.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_018906900.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018903004.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_018912353.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_018908108.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_018901445.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_018904033.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_018903548.1 13 MetaCyc: PWY-7883;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52 "Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series" XP_018901428.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018914569.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_018896406.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018917980.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_018902807.1 5 KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_018907712.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018902320.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_018895899.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018903570.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-2160916 "AURKA Activation by TPX2";"Hyaluronan uptake and degradation" XP_018899583.1 6 MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442 "Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis" XP_018901156.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_018901468.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018908538.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018904060.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018898897.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_018913738.1 7 KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367 "Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" XP_018903429.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018916577.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_018913459.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018916915.1 8 Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9609736 "Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors" XP_018905652.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_018900306.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_018906053.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_018906270.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_018896657.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018917117.1 10 MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-4041 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle" XP_018906786.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018914250.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_018907156.1 9 Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;MetaCyc: PWY-6455;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;MetaCyc: PWY-6454;Reactome: R-HSA-5632681 "Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Vancomycin resistance II";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Vancomycin resistance I";"Ligand-receptor interactions" XP_018898097.1 10 KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385 "Methane metabolism";"Galactose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)" XP_018910495.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018906344.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_018897647.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018915016.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018911596.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018897241.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018902777.1 15 MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-8004 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Entner-Doudoroff pathway I" XP_018911355.1 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_018897948.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018908536.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018916751.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_018903139.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018898957.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490 "Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"MHC class II antigen presentation";"Collagen degradation" XP_018899125.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018909835.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_018913060.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018918222.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018907507.1 14 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-380270;Reactome: R-HSA-2500257;Reactome: R-HSA-5620912;Reactome: R-HSA-2467813;Reactome: R-HSA-2565942;Reactome: R-HSA-68877;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Recruitment of mitotic centrosome proteins and complexes";"Resolution of Sister Chromatid Cohesion";"Anchoring of the basal body to the plasma membrane";"Separation of Sister Chromatids";"Regulation of PLK1 Activity at G2/M Transition";"Mitotic Prometaphase";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_018909613.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_018904419.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018910744.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_018916541.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" XP_018909849.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018911162.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018912076.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_018900745.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518 "MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2" XP_018915251.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018896908.1 10 Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23 "Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"Other glycan degradation" XP_018896173.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_018907664.1 7 Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Signaling by Retinoic Acid" XP_018905625.1 18 Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167287 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery" XP_018908174.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018899314.1 9 Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-3928662;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-6794361 "RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"EPHB-mediated forward signaling";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins" XP_018909669.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018905215.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" XP_018914908.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_018903898.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018913152.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018902490.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018904000.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_018896531.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_018909645.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_018901475.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695 "Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation" XP_018899262.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913496.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Blockage of phagosome acidification" XP_018907790.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018899342.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_018911303.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188 "Neutrophil degranulation";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" XP_018912863.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018899161.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018912171.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_018912489.1 6 Reactome: R-HSA-110362;Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-69166;Reactome: R-HSA-5685939 "POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)" XP_018917716.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_018896455.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018913736.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018902508.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex" XP_018917604.1 7 KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921 "D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation" XP_018913895.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018916910.1 8 Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9609736 "Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors" XP_018910511.1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5041;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6 "Methylation";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism" XP_018902664.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins" XP_018915503.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_018907984.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation" XP_018914887.1 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7724 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_018898015.1 33 Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-4570464 "Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins" XP_018914603.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-167590 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation" XP_018908258.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_018903143.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018895683.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018904225.1 13 MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-1722;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2161;MetaCyc: PWY-7909;MetaCyc: PWY-5030;MetaCyc: PWY-6613 "Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_018895697.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018902567.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018917165.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018899614.1 7 KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4 "Glycerophospholipid metabolism";"Synthesis of PG";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism" XP_018903396.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018913305.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_018900078.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_018902008.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_018909521.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018916281.1 3 MetaCyc: PWY-7979;KEGG: 00515+2.7.1.183;Reactome: R-HSA-5173105 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation" XP_018902119.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_018907852.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_018904980.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_018901628.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_018900350.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_018902658.1 5 KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4 "Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Butanoate metabolism";"Geraniol degradation";"Valine, leucine and isoleucine degradation" XP_018900871.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_018902948.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing" XP_018914989.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018915565.1 5 Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;MetaCyc: PWY-6277 "Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_018904002.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_018896061.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018917346.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018913075.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018909164.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_018896110.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_018910434.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_018917856.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018911537.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_018913244.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018912168.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018899598.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018913770.1 16 Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700 "Oxidative Stress Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_018899847.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018904229.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_018902017.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_018908301.1 6 KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346;MetaCyc: PWY-7820 "Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)" XP_018915765.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_018913432.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018909950.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018896486.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_018908791.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018906803.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_018903572.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018917483.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_018895937.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_018895781.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018916711.1 11 Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380259 "Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes" XP_018917361.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018913144.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_018913741.1 5 MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;Reactome: R-HSA-6798695 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Purine metabolism";"UTP and CTP dephosphorylation I";"Neutrophil degranulation" XP_018915021.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018909919.1 9 Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-69205 "CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"G1/S-Specific Transcription" XP_018915870.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_018916934.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018912666.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_018914124.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_018900079.1 29 Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-427413 "Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression" XP_018896519.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_018910776.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_018914761.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_018900007.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018899269.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913250.1 3 MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade" XP_018910689.1 7 MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism" XP_018902606.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_018914748.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_018917140.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_018901073.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018901580.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018909124.1 5 Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530 "RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_018896669.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-69205 "G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription" XP_018898371.1 3 MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9 "Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_018904350.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018901990.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_018916256.1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453 "Glycerolipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis" XP_018908420.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" XP_018899733.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_018904775.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_018918067.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018897311.1 4 KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;Reactome: R-HSA-209931 "Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis" XP_018903566.1 17 MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-196780;Reactome: R-HSA-163765;MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6722;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;KEGG: 00254+6.4.1.2 "3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"Fatty acid biosynthesis";"Carnitine metabolism";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Glyoxylate assimilation";"Candicidin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Aflatoxin biosynthesis" XP_018914097.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018896373.1 33 Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-168325 "SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis" XP_018907952.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_018905322.1 13 Reactome: R-HSA-1855204;Reactome: R-HSA-9027277;Reactome: R-HSA-2424491;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-202433;MetaCyc: PWY-6351;Reactome: R-HSA-2871796 "Synthesis of IP3 and IP4 in the cytosol";"Erythropoietin activates Phospholipase C gamma (PLCG)";"DAP12 signaling";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Generation of second messenger molecules";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"FCERI mediated MAPK activation" XP_018900718.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018904674.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_018903702.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018902881.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_018914096.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018916229.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813 "Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids" XP_018913849.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018904784.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_018902443.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_018910706.1 8 KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481 "Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate" XP_018917738.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018901143.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_018910978.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_018908438.1 14 MetaCyc: PWY-6842;KEGG: 00450+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-6309;MetaCyc: PWY-6936;MetaCyc: PWY-601;MetaCyc: PWY-801;Reactome: R-HSA-8964539;MetaCyc: PWY-2821;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;Reactome: R-HSA-8964208;KEGG: 00380+2.6.1.7;MetaCyc: PWY-1187 "Glutathione-mediated detoxification II";"Selenocompound metabolism";"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Glutamate and glutamine metabolism";"Glucosinolate biosynthesis from phenylalanine";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Phenylalanine metabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from homomethionine" XP_018901278.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_018911757.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-390471 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis" XP_018904598.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_018902445.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018902454.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_018900872.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_018913299.1 5 Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-201681 "Regulation of PTEN stability and activity";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT" XP_018915650.1 19 Reactome: R-HSA-5687128;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-194840;Reactome: R-HSA-8964616;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5627123;Reactome: R-HSA-983231;Reactome: R-HSA-5626467;Reactome: R-HSA-428543;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-114604;Reactome: R-HSA-389359;Reactome: R-HSA-8950505 "MAPK6/MAPK4 signaling";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"Rho GTPase cycle";"G beta:gamma signalling through CDC42";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate PAKs";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate IQGAPs";"Inactivation of CDC42 and RAC1";"Myogenesis";"DCC mediated attractive signaling";"EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"GPVI-mediated activation cascade";"CD28 dependent Vav1 pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_018901899.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018903935.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_018900352.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_018912627.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_018906741.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_018901407.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_018911894.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_018909487.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_018911519.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_018897650.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018911155.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway" XP_018900614.1 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" XP_018918033.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018913136.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_018903312.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_018900813.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018902683.1 2 Reactome: R-HSA-352230;Reactome: R-HSA-442660 "Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters" XP_018904581.1 6 KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426 "N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_018916983.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-76042 "HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_018899695.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018902595.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_018908383.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism" XP_018903215.1 11 Reactome: R-HSA-8964539;MetaCyc: PWY-381;MetaCyc: PWY-6549;Reactome: R-HSA-210455;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964 "Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II" XP_018899885.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018913506.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_018911785.1 10 Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111457 "Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria" XP_018898603.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_018906055.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_018898111.1 4 MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway" XP_018917176.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018911073.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018904745.1 4 MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;Reactome: R-HSA-964975 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate" XP_018896067.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_018910994.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_018899141.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018916606.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018909483.1 7 MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5469 "Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Sesamin biosynthesis" XP_018909965.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_018897150.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth" XP_018912512.1 12 Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-141444;KEGG: 05235+3.1.3.16;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_018917996.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018908866.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018898405.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_018901657.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_018905084.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_018909315.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018908834.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018916543.1 5 KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_018900178.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_018914890.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis" XP_018903938.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_018900361.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_018902225.1 6 MetaCyc: PWY-6922;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344 "L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)" XP_018907931.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018913211.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_018909618.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018904571.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018909858.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690 "SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events" XP_018901250.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018897808.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_018916051.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_018895778.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018902786.1 9 Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796;Reactome: R-HSA-193648 "GPVI-mediated activation cascade";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation";"NRAGE signals death through JNK" XP_018911335.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018907523.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_018909333.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_018912830.1 3 KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999;Reactome: R-HSA-6806664 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Metabolism of vitamin K" XP_018902310.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_018900747.1 17 Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-111448;Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-6804114;Reactome: R-HSA-9616222;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-1362277;Reactome: R-HSA-139915;Reactome: R-HSA-1362300;Reactome: R-HSA-113501;Reactome: R-HSA-1538133 "G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Activation of NOXA and translocation to mitochondria";"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional regulation of granulopoiesis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Transcription of E2F targets under negative control by DREAM complex";"Activation of PUMA and translocation to mitochondria";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G0 and Early G1" XP_018914900.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557 "Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis" XP_018913609.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018906972.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_018913894.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018916137.1 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" XP_018916712.1 11 Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-380284 "MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_018906520.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018910507.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation" XP_018898909.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-191859;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168 "Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)" XP_018915064.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018907982.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_018901997.1 11 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-6811436 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic" XP_018902962.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018905071.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018900802.1 16 Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-201722;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-2559586;Reactome: R-HSA-3214847;Reactome: R-HSA-5693565 "Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Formation of the beta-catenin:TCF transactivating complex";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"DNA Damage/Telomere Stress Induced Senescence";"HATs acetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_018902665.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_018917059.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I" XP_018899599.1 6 Reactome: R-HSA-110357;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-110373;Reactome: R-HSA-110362 "Displacement of DNA glycosylase by APEX1";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"POLB-Dependent Long Patch Base Excision Repair" XP_018917244.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_018897149.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_018916750.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018906111.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_018917919.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018896241.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018916937.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018896870.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_018905545.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018899360.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_018899640.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands" XP_018911398.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_018899274.1 3 Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9022699 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"MECP2 regulates neuronal receptors and channels" XP_018916857.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_018918111.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-532668 "Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_018904770.1 5 MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6 "D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism" XP_018918038.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018908205.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7115 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_018901235.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018909205.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_018916534.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_018901964.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_018901260.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_018904284.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_018901189.1 31 MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-5994;Reactome: R-HSA-2426168;MetaCyc: PWY-8049;MetaCyc: PWYG-321;MetaCyc: PWY-6113;Reactome: R-HSA-199220;MetaCyc: PWY-7746;Reactome: R-HSA-9029558;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-7858;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-7723 "Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Pederin biosynthesis";"";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Mycobacterial sulfolipid biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Biotin metabolism";"Cis-vaccenate biosynthesis";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence" XP_018910597.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018914469.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018907726.1 7 MetaCyc: PWY-7158;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00400+1.14.16.1;Reactome: R-HSA-2160456 "L-phenylalanine degradation V";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism";"L-tyrosine biosynthesis IV";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylketonuria" XP_018902433.1 29 Reactome: R-HSA-3108214;Reactome: R-HSA-912446;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-5696395;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-3371511;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-5655862;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-3371453;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210 "SUMOylation of DNA damage response and repair proteins";"Meiotic recombination";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Formation of Incision Complex in GG-NER";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"HSF1 activation";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Translesion synthesis by POLK";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_018911679.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018916980.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_018900530.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_018906838.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_018916998.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_018908868.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_018896597.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018903749.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018899858.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_018900974.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018917988.1 7 Reactome: R-HSA-71336;MetaCyc: PWY-8004;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-6906;MetaCyc: PWY-5514;KEGG: 00030+3.1.1.31 "Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway" XP_018896303.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_018904748.1 33 Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-69656;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-69273;Reactome: R-HSA-6781823 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"mRNA Capping";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of TC-NER Pre-Incision Complex" XP_018902940.1 4 Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_018914527.1 3 Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17 "Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism" XP_018903214.1 11 MetaCyc: PWY-6549;Reactome: R-HSA-210455;MetaCyc: PWY-381;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6964;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2 "L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle II";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis" XP_018910666.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_018917474.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_018917347.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_018908434.1 14 MetaCyc: PWY-6309;MetaCyc: PWY-6936;MetaCyc: PWY-2821;Reactome: R-HSA-8964539;MetaCyc: PWY-601;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;Reactome: R-HSA-8964208;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240 "L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Glutamate and glutamine metabolism";"Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Phenylalanine metabolism";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Tryptophan catabolism" XP_018903538.1 18 Reactome: R-HSA-1482801;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4 "Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism" XP_018902296.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_018896994.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis" XP_018913761.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Blockage of phagosome acidification" XP_018906047.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018895798.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_018911158.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018901145.1 11 KEGG: 00250+6.3.5.5;MetaCyc: PWY-5686;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7791;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7400 "Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II";"Pyrimidine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)" XP_018900535.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_018915712.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_018896922.1 10 Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695 "MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Other glycan degradation";"Sphingolipid metabolism";"Neutrophil degranulation" XP_018913319.1 4 Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69202 "Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition" XP_018915766.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_018910265.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018912293.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_018896683.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018916898.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018909904.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_018914066.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018913153.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018913803.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_018916669.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018897863.1 52 Reactome: R-HSA-113418;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-76071;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-76061;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167160 "Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_018911982.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_018909343.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_018898322.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_018915684.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018902257.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656 "TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling" XP_018899414.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557 "Translation initiation complex formation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis" XP_018901725.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_018896086.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018899936.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Amino acids regulate mTORC1" XP_018896491.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_018910718.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018911117.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018896623.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_018913917.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018897713.1 3 Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471 "Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response" XP_018916562.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018905380.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974 "Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA" XP_018901091.1 13 Reactome: R-HSA-5627117;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662 "RHO GTPases Activate ROCKs";"Relaxin signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"EPHB-mediated forward signaling" XP_018911392.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018899369.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_018908379.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_018899561.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018903116.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_018901541.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_018899087.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018914223.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_018908219.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018897076.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_018900721.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018910981.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_018910638.1 8 KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_018917171.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018901860.1 14 MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724 "(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_018897422.1 4 Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275;Reactome: R-HSA-8866427 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Post-translational protein phosphorylation";"VLDLR internalisation and degradation" XP_018901141.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_018910508.1 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II" XP_018896832.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_018897560.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018908726.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_018917232.1 10 Reactome: R-HSA-432720;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-917729;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383 "Lysosome Vesicle Biogenesis";"Negative regulation of MET activity";"Ub-specific processing proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion" XP_018914455.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018914375.1 6 MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;Reactome: R-HSA-913709 "Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins" XP_018896834.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_018913866.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018899823.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_018897306.1 8 MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_018899900.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_018913220.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018900158.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018915871.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4085377 "SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"snRNP Assembly";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins" XP_018908227.1 12 Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-73762;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924 "NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression" XP_018898040.1 17 Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-174084 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_018905810.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_018896570.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_018902830.1 11 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation" XP_018899316.1 5 MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2 "L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism" XP_018918254.1 3 Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_018911410.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_018898027.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_018918044.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018902444.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_018912619.1 3 KEGG: 00040+3.1.1.11;MetaCyc: PWY-7246;MetaCyc: PWY-7248 "Pentose and glucuronate interconversions";"Pectin degradation I";"Pectin degradation II" XP_018898325.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_018916561.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018902789.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018904680.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018897185.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_018900643.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_018913858.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018911478.1 4 Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-1655829 "CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_018913778.1 8 Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Regulation of PTEN localization";"Dual incision in TC-NER" XP_018906394.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018909368.1 4 KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" XP_018896674.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_018900319.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018909481.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_018908488.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_018904507.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_018910618.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_018918051.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018912316.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018899585.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148 "RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_018914339.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_018911307.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_018904676.1 14 KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-2161;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-3661-1;MetaCyc: PWY-1622;MetaCyc: PWY-2201;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-5497 "Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Photorespiration ";"Folate polyglutamylation";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Glycine betaine degradation II (mammalian)";"Formaldehyde assimilation I (serine pathway)";"Folate transformations I";"One carbon pool by folate";"Methane metabolism";"Purine nucleobases degradation II (anaerobic)" XP_018913313.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202 "Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition" XP_018905066.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_018909962.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_018897084.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_018909001.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018902345.1 12 MetaCyc: PWY-6708;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-5873;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;MetaCyc: PWY-5857 "Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)" XP_018897541.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_018896226.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-430039;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway" XP_018901232.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex" XP_018914148.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_018906565.1 20 KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858 "beta-Alanine metabolism";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II" XP_018913117.1 1 Reactome: R-HSA-6804115 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_018912663.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_018912498.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_018904159.1 6 Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-194840;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36 "Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Rho GTPase cycle";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism" XP_018899116.1 5 Reactome: R-HSA-392154;Reactome: R-HSA-1222556;MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39 "Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"Arginine biosynthesis" XP_018898780.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_018901427.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018917129.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018908840.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_018918083.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_018916861.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018906102.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_018899609.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018914001.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_018900940.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018917049.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_018910348.1 56 Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8939902 "Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity" XP_018905910.1 7 Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Pyruvate metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_018895658.1 21 MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;MetaCyc: PWY-7198;MetaCyc: PWY-7221;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7222;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7205 "UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation" XP_018903970.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_018909366.1 4 KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis" XP_018902306.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)" XP_018899142.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_018899941.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_018904031.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_018905106.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_018898912.1 5 Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131 "Collagen degradation";"MHC class II antigen presentation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR" XP_018913850.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_018902680.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_018907454.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_018906534.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018907986.1 7 Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Pyruvate metabolism" XP_018897411.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex" XP_018912030.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_018906893.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018906268.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_018898802.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_018917794.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018914602.1 8 Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Blockage of phagosome acidification";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_018916449.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018917470.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018902860.1 6 Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920 "Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)" XP_018909516.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018905387.1 10 Reactome: R-HSA-72695;Reactome: R-HSA-381042;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-382556;Reactome: R-HSA-72731;Reactome: R-HSA-9648895;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"PERK regulates gene expression";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ABC-family proteins mediated transport";"Recycling of eIF2:GDP";"Response of EIF2AK1 (HRI) to heme deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_018899267.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018906598.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_018908519.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018915937.1 4 MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate" XP_018898158.1 7 KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;Reactome: R-HSA-446205 "Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose" XP_018916905.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_018915003.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018896511.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"PKA activation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_018912748.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018905294.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_018906382.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018898774.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_018917925.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_018909102.1 13 MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-6859;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7182;MetaCyc: PWY-7659;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-5122 "Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Geranyl diphosphate biosynthesis" XP_018909073.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_018913728.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018897632.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018904578.1 6 Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952 "Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_018913683.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_018909493.1 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471;Reactome: R-HSA-196741 "Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_018900391.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_018903936.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_018912388.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_018895674.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018898013.1 33 Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-9648025 "Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation" XP_018914903.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018909203.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_018906652.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_018908856.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_018912415.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_018895794.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018913419.1 8 Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-922;MetaCyc: PWY-7524;Reactome: R-HSA-191273 "Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis" XP_018907803.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_018900741.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_018912006.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_018898464.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259 "Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes" XP_018914475.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_018901939.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018898191.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-1834949 "IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA" XP_018909510.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_018914681.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_018912456.1 9 KEGG: 00550+2.4.1.227;MetaCyc: PWY-6385;Reactome: R-HSA-5633231;MetaCyc: PWY-6470;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00513+2.4.1.141 "Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Various types of N-glycan biosynthesis" XP_018896467.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-170670 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway" XP_018899716.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_018912856.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_018908602.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018905352.1 5 Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5610787 "Hedgehog 'on' state";"Activation of SMO";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state" XP_018898809.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_018906309.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER" XP_018913039.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_018914728.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_018912749.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018899344.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_018905585.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_018907476.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_018917952.1 18 KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00220+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6642;MetaCyc: PWY-7115;KEGG: 00400+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643 "Novobiocin biosynthesis";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism";"Arginine and proline metabolism";"Sulfolactate degradation III";"Arginine biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II" XP_018908605.1 6 KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism" XP_018905090.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_018897056.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_018916824.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018914425.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018909900.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_018912965.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018895593.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_018900647.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018913026.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018906563.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_018900337.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018909470.1 10 Reactome: R-HSA-1989781;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10 "PPARA activates gene expression";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Butanoate metabolism";"Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"Ferrichrome A biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis" XP_018904488.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018905094.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_018909731.1 1 Reactome: R-HSA-419771 "Opsins" XP_018917836.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829 "Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_018911926.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_018911180.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_018917233.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018904191.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_018897578.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018903777.1 10 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;Reactome: R-HSA-201722 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"HATs acetylate histones";"Relaxin signaling pathway";"Ub-specific processing proteases";"Formation of the beta-catenin:TCF transactivating complex" XP_018905806.1 4 Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLI" XP_018914350.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_018916244.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_018909636.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression" XP_018906428.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_018906419.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_018899382.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_018911098.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018913280.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_018911101.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018895682.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018907558.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_018910126.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_018912658.1 1 KEGG: 00970+6.1.1.5 "Aminoacyl-tRNA biosynthesis" XP_018913529.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_018908054.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_018899638.1 17 Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-1834949;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-3270619;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586 "Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Cytosolic sensors of pathogen-associated DNA";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"IRF3-mediated induction of type I IFN";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence" XP_018899717.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_018898115.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_018902832.1 57 Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236 "Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"UCH proteinases";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Neddylation";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Degradation of AXIN";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_018910715.1 3 KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44 "Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_018896856.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018913561.1 5 Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-936964;Reactome: R-HSA-933541 "TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation" XP_018897988.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018912389.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_018914296.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018911974.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_018898114.1 5 Reactome: R-HSA-2206305;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857 "MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Keratan sulfate degradation" XP_018900552.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018913249.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_018914391.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_018916413.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_018907137.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_018901395.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_018914030.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex" XP_018917742.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_018895813.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits" XP_018909136.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_018905602.1 6 KEGG: 00040+5.1.3.1;KEGG: 00710+5.1.3.1;MetaCyc: PWY-1861;Reactome: R-HSA-71336;MetaCyc: PWY-5723;KEGG: 00030+5.1.3.1 "Pentose and glucuronate interconversions";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Rubisco shunt";"Pentose phosphate pathway" XP_018907857.1 6 Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00270+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52 "Serine biosynthesis";"Glycine, serine and threonine metabolism";"Vitamin B6 metabolism";"Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism" XP_018916573.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_018912303.1 8 Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69183 "Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand" XP_018900660.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607 "G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends" XP_018901130.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_018904304.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018898822.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_018903024.1 31 MetaCyc: PWY-7858;MetaCyc: PWY-6519;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-4381;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-5973;Reactome: R-HSA-163765;MetaCyc: PWY-7746;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-6113;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-5966-1;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-8047;MetaCyc: PWY-5971;MetaCyc: PWY-6799;MetaCyc: PWY-5147;MetaCyc: PWY-5142;MetaCyc: PWY-5367;Reactome: R-HSA-2426168;MetaCyc: PWY-6282;MetaCyc: PWY-5994 "(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Cis-vaccenate biosynthesis";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Biotin metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis I (plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis (animals and fungi, cytoplasm)" XP_018913307.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_018903714.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_018897940.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_018909080.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-69473 "Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint" XP_018913764.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018916676.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_018915459.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018905087.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_018908399.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-380972 "Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"mTOR signalling";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_018908097.1 12 MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-601;MetaCyc: PWY-801;MetaCyc: PWY-6936;MetaCyc: PWY-6309;MetaCyc: PWY-7901;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842 "Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Selenocompound metabolism";"Glutathione-mediated detoxification II" XP_018897942.1 11 Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-8863795;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-2219530 "PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_018912419.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018914002.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_018917831.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_018905318.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_018917138.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_018904905.1 14 MetaCyc: PWY-5667;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51 "CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Glycerolipid metabolism" XP_018898294.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_018911819.1 12 Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167290 "Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation" XP_018915410.1 33 Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-170822 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_018902388.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_018912471.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_018905534.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_018899193.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_018905224.1 3 KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096 "Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation" XP_018909678.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" XP_018910027.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_018902127.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018918060.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018897835.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_018902638.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_018914401.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-202433;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Generation of second messenger molecules";"Regulation of actin dynamics for phagocytic cup formation" XP_018899905.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018908175.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_018897271.1 12 MetaCyc: PWY-6978;MetaCyc: PWY-5857;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-5855;Reactome: R-HSA-1268020;MetaCyc: PWY-5871;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;MetaCyc: PWY-6708 "Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_018903941.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_018913538.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_018913293.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018895732.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance" XP_018902453.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_018914460.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_018917030.1 2 Reactome: R-HSA-5083628;Reactome: R-HSA-5173105 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation" XP_018907262.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018904675.1 14 MetaCyc: PWY-1622;Reactome: R-HSA-196757;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-2161 "Formaldehyde assimilation I (serine pathway)";"Metabolism of folate and pterines";"Glycine betaine degradation II (mammalian)";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Methane metabolism";"One carbon pool by folate";"Photorespiration ";"Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Folate transformations II (plants)";"Folate polyglutamylation" XP_018912011.1 8 Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Ion channel transport";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" XP_018910154.1 15 Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580 "Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Oxidative Stress Induced Senescence" XP_018896768.1 31 MetaCyc: PWY-5994;MetaCyc: PWY-6282;Reactome: R-HSA-2426168;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-5147;MetaCyc: PWY-6799;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-7723;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7858;MetaCyc: PWY-6519;Reactome: R-HSA-199220;MetaCyc: PWYG-321;MetaCyc: PWY-6113;MetaCyc: PWY-8049;MetaCyc: PWY-7746;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;MetaCyc: PWY-5973;MetaCyc: PWY-8012;MetaCyc: PWY-7664 "Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Vitamin B5 (pantothenate) metabolism";"";"Superpathway of mycolate biosynthesis";"Pederin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Biotin metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Cis-vaccenate biosynthesis";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)" XP_018916310.1 5 Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32 "Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism" XP_018902528.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_018902510.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_018914227.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_018896617.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018903511.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_018904900.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" YP_086814.1 7 Reactome: R-HSA-611105;KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198;MetaCyc: PWY-6692;MetaCyc: PWY-4302;MetaCyc: PWY-5083;MetaCyc: PWY-3781 "Respiratory electron transport";"Oxidative phosphorylation";"Complex I biogenesis";"Fe(II) oxidation";"Aerobic respiration III (alternative oxidase pathway)";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration I (cytochrome c)" XP_018908815.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_018900065.1 13 Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-416993;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-437239 "LDL clearance";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1" XP_018902337.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018895775.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_018897941.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159231 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_018896776.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018896587.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_018917088.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_018911311.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_018907055.1 4 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_018900736.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-380284 "MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_018897930.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-380994 "PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_018912836.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_018907696.1 4 Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis" XP_018910615.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_018898834.1 18 MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839 "Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Synthesis of PA";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE" XP_018902032.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018912158.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018912178.1 3 KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B "Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates" XP_018905287.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_018900980.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018912062.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_018917513.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_018910057.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_018917303.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018911139.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_018913721.1 5 Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-5610787;Reactome: R-HSA-373080 "Activation of SMO";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state";"Class B/2 (Secretin family receptors)" XP_018909628.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_018900677.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" XP_018901855.1 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7724 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_018907059.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018913998.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_018916492.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018898847.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_018910347.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018912296.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_018911068.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_018908112.1 6 Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-622 "Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis" XP_018910917.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_018898413.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_018903832.1 14 Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167287 "RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery" XP_018906890.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080 "Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I" XP_018906224.1 5 KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;Reactome: R-HSA-197264 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinamide salvaging" XP_018914590.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_018908150.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_018917206.1 3 MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099 "L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling" XP_018917985.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_018912525.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_018904021.1 17 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_018916875.1 4 Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483 "Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)" XP_018915947.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_018902202.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_018904612.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_018899025.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_018900499.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_018914017.1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-983189 "Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Kinesins" XP_018909755.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018915881.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_018904522.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_018900760.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_018913058.1 9 Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Human cytomegalovirus infection";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway" XP_018899429.1 5 MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;Reactome: R-HSA-9627069;Reactome: R-HSA-111458 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism";"Regulation of the apoptosome activity";"Formation of apoptosome" XP_018909670.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018900635.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_018908221.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276 "Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Degradation of AXIN";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Neddylation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_018914463.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018914749.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_018896007.1 12 MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70171 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis" XP_018914904.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018914194.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-141444 "Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_018899338.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_018910612.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_018899519.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_018915949.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_018910657.1 6 MetaCyc: PWY-6829;Reactome: R-HSA-8868766;MetaCyc: PWY-7285;Reactome: R-HSA-6785470;MetaCyc: PWY-7286;Reactome: R-HSA-6787450 "Trna methylation (yeast)";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"tRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the mitochondrion" XP_018897382.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_018910731.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170 "MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_018912404.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-532668 "Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_018910906.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_018908433.1 14 MetaCyc: PWY-6309;MetaCyc: PWY-6936;MetaCyc: PWY-2821;Reactome: R-HSA-8964539;MetaCyc: PWY-801;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;Reactome: R-HSA-8964208;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240 "L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Glutamate and glutamine metabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Phenylalanine metabolism";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Tryptophan catabolism" XP_018918180.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018918110.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-8957275 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation" XP_018909702.1 4 KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_018898377.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018911315.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_018911356.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_018909462.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_018915980.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018905586.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_018896783.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018906639.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_018908037.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_018909955.1 3 Reactome: R-HSA-446193;Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis" XP_018906280.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018897476.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_018914056.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018895604.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018900722.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018903097.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_018898238.1 10 MetaCyc: PWY-6317;MetaCyc: PWY-7344;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-6397 "D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis" XP_018917413.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_018909486.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_018914258.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_018898327.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_018910030.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_018903778.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018909673.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_018899042.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_018902959.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_018903292.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018912334.1 7 Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168333 "Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_018900913.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_018914769.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_018913359.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_018910600.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_018900960.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_018915235.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018913781.1 6 KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;MetaCyc: PWY-7761;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism" XP_018908393.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601 "Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_018910806.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_018903355.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection" XP_018912061.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_018896718.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_018896929.1 10 KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Other glycan degradation";"Sphingolipid metabolism";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Glycosaminoglycan degradation" XP_018917025.1 2 Reactome: R-HSA-5173105;Reactome: R-HSA-5083628 "O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_018907442.1 7 Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-140837;Reactome: R-HSA-8957275;Reactome: R-HSA-416476 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"G alpha (i) signalling events";"Peptide ligand-binding receptors";"Intrinsic Pathway of Fibrin Clot Formation";"Post-translational protein phosphorylation";"G alpha (q) signalling events" XP_018907402.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_018900232.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_018905520.1 8 Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-983231 "PKA activation in glucagon signalling";"PKA activation";"Hedgehog 'off' state";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production" XP_018909561.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation" XP_018912910.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_018914778.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_018909069.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_018916291.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018903144.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_018914760.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_018911798.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_018899207.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_018905603.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_018917868.1 6 Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403 "Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)" XP_018911057.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_018904293.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018901270.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080 "Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I" XP_018914295.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_018897997.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_018899148.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_018904869.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_018917188.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation" XP_018910086.1 6 Reactome: R-HSA-5358565;Reactome: R-HSA-5545483;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2" XP_018897464.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_018914824.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-170660 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway" XP_018903850.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_018906073.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation" XP_018917986.1 33 Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-165054 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA" XP_018899474.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_018895944.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_018900995.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_018910364.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_018905201.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-5619107 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_018899518.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181430 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle" XP_018918216.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018903185.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_018912023.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_018911163.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_018902327.1 2 KEGG: 00900+2.7.7.60;MetaCyc: PWY-7560 "Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II" XP_018902180.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018912284.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_018899984.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490 "Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Collagen degradation" XP_018909924.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018903912.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_018904986.1 8 Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-9648025 "SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation" XP_018901635.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018916994.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_018909461.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_018912028.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_018915782.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" XP_018918219.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018896893.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_018907571.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_018906854.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_018916698.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_018901035.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_018895596.1 4 KEGG: 00770+6.3.2.1;KEGG: 00770+2.1.2.11;KEGG: 00410+6.3.2.1;MetaCyc: PWY-6654 "Pantothenate and CoA biosynthesis";"Pantothenate and CoA biosynthesis";"beta-Alanine metabolism";"Phosphopantothenate biosynthesis III (archaebacteria)" XP_018910599.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_018904576.1 6 MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143 "Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis" XP_018908337.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018910759.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_018896900.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_018910675.1 9 Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955 "Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_018907416.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_018901182.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_018895590.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_018896607.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018916874.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_018908880.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_018906710.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_018897554.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_018901151.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_018897165.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_018907804.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_018899494.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_018909918.1 4 KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558 "Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine" XP_018913937.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_018917817.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_018898646.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_018913873.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK" XP_018906495.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_018911290.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_018902865.1 57 Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome" XP_018898434.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_018898844.1 56 Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128 "Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling" XP_018917473.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_018902923.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_018899463.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_018914437.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_018898331.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_018913176.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_018904610.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_018908947.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_018896188.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs" XP_018897412.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_018907022.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_018908601.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_018916531.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_018903787.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-5099900 "Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4" XP_018902130.1 5 KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37 "Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism" XP_018917169.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_018907871.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_018901031.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_018903851.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_018897553.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_018902668.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_018900188.1 6 Reactome: R-HSA-983168;Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-8863795;Reactome: R-HSA-2173788;Reactome: R-HSA-8948751 "Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN stability and activity" XP_018899724.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_018913440.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_018900961.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_018916981.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_018900751.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018906071.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_018909491.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_018905028.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_018904244.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_018901686.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_018902656.1 5 KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4 "Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Geraniol degradation" XP_018901852.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080 "Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I" XP_018909671.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase" XP_018902967.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_018900753.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018916727.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-111932 "Ion transport by P-type ATPases";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF activation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB" XP_018901415.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_018910257.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_018915002.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_018910690.1 24 Reactome: R-HSA-2730905;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-9634635;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-114604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-354192;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-165158;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2871837 "Role of LAT2/NTAL/LAB on calcium mobilization";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Estrogen-stimulated signaling through PRKCZ";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"Downstream TCR signaling";"RSK activation";"Human cytomegalovirus infection";"VEGFR2 mediated cell proliferation";"GPVI-mediated activation cascade";"Relaxin signaling pathway";"Integrin signaling";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Activation of AKT2";"Thermogenesis";"FCERI mediated NF-kB activation" XP_018908172.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_018907259.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_018899831.1 14 Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-5687128;Reactome: R-HSA-9648025;Reactome: R-HSA-450520;Reactome: R-HSA-2173788;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-69273;Reactome: R-HSA-68877;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-3769402 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"MAPK6/MAPK4 signaling";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA";"Downregulation of TGF-beta receptor signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cyclin A/B1/B2 associated events during G2/M transition";"Mitotic Prometaphase";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Deactivation of the beta-catenin transactivating complex" XP_018897995.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_018897803.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_018917456.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_018914443.1 18 MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7224;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7176;Reactome: R-HSA-5624138;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7227 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Trafficking of myristoylated proteins to the cilium";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_018912501.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_018911861.1 2 Reactome: R-HSA-114608;Reactome: R-HSA-2132295 "Platelet degranulation";"MHC class II antigen presentation" XP_018898717.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_018914878.1 13 MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_018914677.1 18 MetaCyc: PWY-7205;MetaCyc: PWY-7184;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7176 "CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis" XP_018913768.1 16 Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593 "Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity" XP_018912364.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_018904771.1 5 MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation" XP_018902373.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_018918242.1 8 Reactome: R-HSA-6791461;Reactome: R-HSA-71336;KEGG: 00051+5.3.1.6;MetaCyc: PWY-5723;Reactome: R-HSA-5659996;KEGG: 00710+5.3.1.6;MetaCyc: PWY-1861;KEGG: 00030+5.3.1.6 "RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Rubisco shunt";"RPIA deficiency: failed conversion of R5P to RU5P";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway" XP_018896917.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_018902259.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" XP_018900145.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters"