Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_050489065.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation" XP_050491493.1 5 Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Interleukin-7 signaling" XP_050480097.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050476985.1 42 Reactome: R-HSA-2559580;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-110328;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-8939236;Reactome: R-HSA-427359;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-5334118;Reactome: R-HSA-110330;Reactome: R-HSA-5250924;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-110329;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-171306;Reactome: R-HSA-73772;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-212300;Reactome: R-HSA-73728;Reactome: R-HSA-606279;Reactome: R-HSA-5693565 "Oxidative Stress Induced Senescence";"HDACs deacetylate histones";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SIRT1 negatively regulates rRNA expression";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected purine";"B-WICH complex positively regulates rRNA expression";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"RMTs methylate histone arginines";"Cleavage of the damaged pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Escape";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"PRC2 methylates histones and DNA";"RNA Polymerase I Promoter Opening";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_050484301.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050485525.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_050480509.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_050496930.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050489499.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_050485075.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_050482507.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_050493740.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_050472560.1 3 Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5 "Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation" XP_050483904.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_050475527.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_050488175.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_050485283.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_050472130.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_050477231.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5628897 "Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling";"TP53 Regulates Metabolic Genes" XP_050472171.1 3 KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662;MetaCyc: PWY-7277 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)" XP_050473805.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050476041.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050473735.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050472339.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050473803.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050496917.1 3 Reactome: R-HSA-2173791;Reactome: R-HSA-4608870;Reactome: R-HSA-420029 "TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Asymmetric localization of PCP proteins";"Tight junction interactions" XP_050483332.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation" XP_050483088.1 8 Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68949 "CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin" XP_050488531.1 3 Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517 "cGMP effects";"Ca2+ pathway";"Rap1 signalling" XP_050491221.1 29 Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772 "Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape" XP_050491576.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_050490986.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_050493388.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050488658.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_050494522.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_050495832.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_050482156.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050482009.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_050481991.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050482236.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_050490298.1 5 MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_050475476.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" XP_050484669.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_050482243.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_050473398.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050496185.1 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" XP_050481816.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050478085.1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis" XP_050491538.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_050492833.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050496434.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_050481655.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_050474325.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050493756.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050487645.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050487053.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_050486799.1 5 KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway" XP_050474177.1 3 Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741 "Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_050485734.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050471055.1 6 KEGG: 00710+5.1.3.1;KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;Reactome: R-HSA-71336;MetaCyc: PWY-1861 "Carbon fixation in photosynthetic organisms";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Rubisco shunt";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_050471964.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050469631.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane" XP_050472205.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_050469776.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_050483651.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050487107.1 10 MetaCyc: PWY-5839;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5844;MetaCyc: PWY-5849;MetaCyc: PWY-5892;MetaCyc: PWY-5895;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5891;MetaCyc: PWY-7996 "Menaquinol-7 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-13 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-4 biosynthesis I" XP_050470969.1 5 KEGG: 00790+3.4.19.9;KEGG: 00513+2.4.1.142;MetaCyc: PWY-2161B;KEGG: 00510+2.4.1.142;Reactome: R-HSA-6798695 "Folate biosynthesis";"Various types of N-glycan biosynthesis";"Glutamate removal from folates";"N-Glycan biosynthesis";"Neutrophil degranulation" XP_050485757.1 7 Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;MetaCyc: PWY-7886;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-7818 "Synthesis of PC";"Glycerophospholipid metabolism";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)" XP_050479639.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_050477486.1 5 MetaCyc: PWY-6129;Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;Reactome: R-HSA-446199 "Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate" XP_050469760.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_050473417.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050485725.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050496513.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050472453.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_050496199.1 5 MetaCyc: PWY-8043;Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3 "Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism" XP_050469702.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050480526.1 3 Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942 "Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)" XP_050473968.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050492292.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050472103.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050493226.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_050475518.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_050493516.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_050481458.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_050477482.1 5 Reactome: R-HSA-4755579;MetaCyc: PWY-6129;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199 "Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate" XP_050494377.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_050471696.1 10 MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-7559 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway" XP_050487390.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_050473397.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050492730.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050469372.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_050474539.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050473096.1 10 Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201 "Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis" XP_050482462.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050491688.1 8 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_050473558.1 7 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-373753 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Nephrin family interactions" XP_050495779.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516 "Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin" XP_050491178.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050474054.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050470600.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050472524.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878 "COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport" XP_050484354.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_050490913.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_050484290.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050496926.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050491870.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050482557.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_050474169.1 7 KEGG: 00360+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208 "Phenylalanine metabolism";"L-tyrosine biosynthesis IV";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V";"Phenylketonuria";"Phenylalanine metabolism" XP_050484018.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_050479901.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050470418.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_050482473.1 6 Reactome: R-HSA-6796648;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5632927 "TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3" XP_050482860.1 5 KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-3781 "Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)" XP_050477472.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_050476154.1 4 MetaCyc: PWY-6482;Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493 "Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2" XP_050497038.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050493630.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050477255.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_050485304.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050493721.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_050481689.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050480106.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050485069.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_050487331.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_050475846.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_050476946.1 8 Reactome: R-HSA-1855183;KEGG: 00562+5.5.1.4;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-6372;MetaCyc: PWY-4661;MetaCyc: PWY-6664;MetaCyc: PWY-2301 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis" XP_050485291.1 3 MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099 "L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling" XP_050473388.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050469394.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050472490.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050492303.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_050469568.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_050473736.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_050475264.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_050489897.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_050476947.1 4 KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" XP_050493109.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_050470074.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050474416.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_050481699.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050487844.1 11 Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_050474424.1 7 KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2 "Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis" XP_050474282.1 4 KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)" XP_050476162.1 5 KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68 "Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_050493610.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_050471528.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_050477997.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_050493208.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050477263.1 9 Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-113501 "Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" XP_050490276.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050480322.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050492475.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_050475141.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050483008.1 5 MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-7761 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)" XP_050484305.1 4 Reactome: R-HSA-446210;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906 "Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_050488946.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050484000.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Photosynthesis";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"ATP biosynthesis";"Amino acids regulate mTORC1" XP_050478742.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_050483619.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_050487687.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" XP_050471615.1 5 Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321 "Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_050483850.1 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" XP_050494001.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_050474730.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_050486289.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_050474432.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_050476308.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050478475.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050482521.1 19 Reactome: R-HSA-5626467;Reactome: R-HSA-5687128;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-114604;Reactome: R-HSA-3928662;Reactome: R-HSA-525793;Reactome: R-HSA-8964616;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-182971 "RHO GTPases activate IQGAPs";"MAPK6/MAPK4 signaling";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"DCC mediated attractive signaling";"RHO GTPases activate KTN1";"GPVI-mediated activation cascade";"EPHB-mediated forward signaling";"Myogenesis";"G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"EGFR downregulation" XP_050472049.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_050470296.1 6 MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-6174;KEGG: 00900+2.7.1.36 "Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis" XP_050472025.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_050479594.1 8 Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-111458;Reactome: R-HSA-8953750 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"Formation of apoptosome";"Transcriptional Regulation by E2F6" XP_050473935.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_050491787.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_050474833.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050470699.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050484789.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779 "RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_050474498.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_050479593.1 8 Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_050484155.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050482339.1 7 Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;MetaCyc: PWY-7221;MetaCyc: PWY-5695;Reactome: R-HSA-73817;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596 "Neutrophil degranulation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I" XP_050493735.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050484906.1 7 Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1362300 "Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_050486403.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2 "Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism" XP_050484004.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050474214.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_050470476.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_050490740.1 19 Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-8856825 "VLDL assembly";"VLDL clearance";"Platelet sensitization by LDL";"LDL clearance";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"LDL remodeling";"Scavenging by Class H Receptors";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Chylomicron assembly";"Chylomicron clearance";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis" XP_050477778.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling" XP_050480355.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_050484150.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050476849.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050480041.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_050496401.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050471613.1 5 Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence" XP_050480313.1 3 KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_050485685.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Aggrephagy" XP_050481428.1 15 Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944 "Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2" XP_050470577.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050480714.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050477594.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9609736 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors" XP_050470687.1 33 Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-141444 "Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050475666.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050493628.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050487563.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_050490220.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050489936.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_050480237.1 10 MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6372;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362 "1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_050480329.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_050478039.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_050470824.1 8 Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER" XP_050472609.1 6 MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;Reactome: R-HSA-73817 "Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_050470187.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_050487000.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_050469460.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_050489987.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_050482769.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_050489999.1 3 Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110357 "Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1" XP_050483350.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_050485132.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974 "Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA" XP_050472250.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050484077.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050471139.1 2 Reactome: R-HSA-2206307;Reactome: R-HSA-2024096 "MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation" XP_050489051.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_050473386.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050476578.1 10 MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Fructose and mannose metabolism";"Galactose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)" XP_050481972.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_050475686.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_050473355.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050495355.1 11 Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631 "SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility" XP_050485045.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_050490999.1 15 Reactome: R-HSA-5358752;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262 "T41 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_050469452.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_050473123.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-114608 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation" XP_050471262.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_050472132.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase" XP_050478859.1 8 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Neutrophil degranulation" XP_050476095.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_050478803.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050482766.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050479248.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_050470374.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050496362.1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368082 "Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"RORA activates gene expression" XP_050476494.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins" XP_050496824.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050480494.1 24 KEGG: 05163+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165158;KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated cell proliferation";"RSK activation";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"Activation of AKT2";"Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Downstream TCR signaling";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"Thermogenesis";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway" XP_050485164.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050490255.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_050473822.1 5 Reactome: R-HSA-6804756;Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-6811555;Reactome: R-HSA-5668599 "Regulation of TP53 Activity through Phosphorylation";"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases" XP_050486223.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_050493775.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_050485766.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_050485705.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport" XP_050481980.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "Clathrin-mediated endocytosis";"Neutrophil degranulation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_050484418.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_050471888.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_050478741.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_050479229.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_050493373.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_050480028.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_050495541.1 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" XP_050496589.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050479443.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69166 "DNA replication initiation";"Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate" XP_050484709.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_050470891.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_050482793.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_050489275.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_050496834.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050485295.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050484979.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_050475193.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_050479785.1 2 MetaCyc: PWY-8061;Reactome: R-HSA-2393930 "8-oxo-(d)GTP detoxification II";"Phosphate bond hydrolysis by NUDT proteins" XP_050470599.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050473061.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_050487696.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050471476.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050492082.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_050478830.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_050486904.1 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" XP_050488570.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification" XP_050480092.1 24 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;Reactome: R-HSA-2871837;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;Reactome: R-HSA-392451;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;Reactome: R-HSA-202424;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-9634635;Reactome: R-HSA-354192;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated cell proliferation";"RSK activation";"FCERI mediated NF-kB activation";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"Activation of AKT2";"RHO GTPases activate PKNs";"G beta:gamma signalling through PI3Kgamma";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"Downstream TCR signaling";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"Thermogenesis";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Estrogen-stimulated signaling through PRKCZ";"Integrin signaling";"PI3K-Akt signaling pathway" XP_050470302.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050481312.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_050473399.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050490983.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_050472248.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050483455.1 10 MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-7559 "Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway" XP_050470957.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050474722.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_050489006.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050475582.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_050491708.1 4 MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23 "Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism" XP_050488575.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" XP_050470606.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_050481982.1 56 Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702 "Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"UCH proteinases";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling" XP_050473337.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050474285.1 13 KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916 "Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation" XP_050489074.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_050486765.1 10 KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"RSK activation";"Human cytomegalovirus infection";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway" XP_050493227.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_050469398.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050471794.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050476382.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_050488354.1 14 Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5656121 "Polymerase switching";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI" XP_050495896.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050472851.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050471136.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050478502.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050478393.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_050486941.1 5 Reactome: R-HSA-917937;Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603 "Iron uptake and transport";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"Neddylation";"UCH proteinases" XP_050487986.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050472743.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_050469629.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_050492534.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_050481392.1 5 MetaCyc: PWY-4361;Reactome: R-HSA-111458;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;Reactome: R-HSA-9627069 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Methionine salvage pathway";"Cysteine and methionine metabolism";"Regulation of the apoptosome activity" XP_050475144.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050496209.1 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" XP_050471810.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_050471716.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050487973.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_050471374.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_050483760.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols" XP_050472469.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_050491508.1 5 Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"Interleukin-7 signaling" XP_050494384.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_050483291.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_050488162.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_050486932.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_050469584.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_050478243.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_050495313.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis" XP_050483349.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_050490283.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050491865.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050483393.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050482813.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050478928.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050489935.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_050481703.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050493286.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050483694.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_050488668.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050473122.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"Post-translational protein phosphorylation" XP_050477637.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_050480236.1 10 KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-4661 "Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_050478016.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050491490.1 5 Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509 "Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes" XP_050470585.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_050482783.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_050489659.1 3 Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096 "MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation" XP_050482859.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050493552.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_050483125.1 5 Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Dual incision in TC-NER" XP_050475234.1 56 Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050 "Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Degradation of DVL";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_050485966.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050488251.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050479840.1 4 MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49 "Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway" XP_050477659.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_050491501.1 5 Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695 "Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling" XP_050485751.1 7 MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-7886;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483191 "Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PC" XP_050481227.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050483858.1 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" XP_050487273.1 10 MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7571;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00650+2.3.3.10 "Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Ferrichrome A biosynthesis";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Butanoate metabolism" XP_050478570.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050479751.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_050481184.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_050474071.1 20 MetaCyc: PWY-5136;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920 "Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Fatty acid degradation";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)" XP_050481391.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_050477911.1 15 KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-7383;MetaCyc: PWY-8004;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7218 "Pyruvate metabolism";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_050474816.1 11 Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670 "Hedgehog 'off' state";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway" XP_050472489.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050480130.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050471312.1 4 Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I" XP_050484197.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050488193.1 7 Reactome: R-HSA-201688;Reactome: R-HSA-201681;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258 "WNT mediated activation of DVL";"TCF dependent signaling in response to WNT";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL" XP_050482319.1 5 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling" XP_050480926.1 11 KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-7821;MetaCyc: PWY-6545 "Pantothenate and CoA biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Starch and sucrose metabolism";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_050479028.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050482453.1 4 Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_050470756.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_050472302.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_050490500.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_050474286.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_050488547.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692 "Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity" XP_050487690.1 6 Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8963889 "CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes" XP_050469918.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_050494244.1 10 MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051 "Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I" XP_050476902.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_050479946.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050485653.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050476324.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050478053.1 3 Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989 "TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" XP_050488192.1 7 Reactome: R-HSA-4641262;Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-5663220 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"PCP/CE pathway";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"RHO GTPases Activate Formins" XP_050482417.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050472121.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050485117.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_050489631.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921 "Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_050477653.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_050472155.1 16 Reactome: R-HSA-3134963;Reactome: R-HSA-209543;Reactome: R-HSA-1236974;Reactome: R-HSA-166058;Reactome: R-HSA-9020702;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-975138;Reactome: R-HSA-5602680;Reactome: R-HSA-1257604;Reactome: R-HSA-5602498;Reactome: R-HSA-1810476;Reactome: R-HSA-5603037;Reactome: R-HSA-6811558;Reactome: R-HSA-975871;Reactome: R-HSA-975155 "DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"p75NTR recruits signalling complexes";"ER-Phagosome pathway";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Interleukin-1 signaling";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 deficiency (TLR5)";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR5)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome" XP_050489459.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288 "TP53 Regulates Metabolic Genes";"mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1" XP_050482659.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_050484949.1 5 MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22 "Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism" XP_050480233.1 10 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6361 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)" XP_050488173.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_050481098.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050482864.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050490652.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050483385.1 20 MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920 "10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)" XP_050473434.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol" XP_050494049.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_050487947.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_050484368.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050469580.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_050478132.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_050476490.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050479934.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_050477864.1 7 Reactome: R-HSA-5633231;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6471;MetaCyc: PWY-6385;Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6470 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis III (mycobacteria)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)" XP_050490495.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_050492002.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Stearate biosynthesis I (animals)" XP_050472824.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050475397.1 9 Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6781823 "Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex" XP_050475478.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic" XP_050481679.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050482687.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050481647.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050482388.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050470961.1 9 Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897 "mTOR signalling";"mTORC1-mediated signalling";"MAP2K and MAPK activation";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes" XP_050490919.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050486281.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_050477165.1 26 Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-8866654;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-1362277;Reactome: R-HSA-110314;Reactome: R-HSA-4615885;Reactome: R-HSA-69091;Reactome: R-HSA-6804114;Reactome: R-HSA-110312;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-6782135;Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-174414;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397 "PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Transcription of E2F targets under negative control by DREAM complex";"Recognition of DNA damage by PCNA-containing replication complex";"SUMOylation of DNA replication proteins";"Polymerase switching";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by REV1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Dual incision in TC-NER";"G1/S-Specific Transcription";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_050489611.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050478751.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_050486169.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050484923.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_050490526.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_050493186.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_050471638.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_050480854.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516 "Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin" XP_050479111.1 7 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Deadenylation of mRNA";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition" XP_050483723.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050496949.1 4 KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Selenocompound metabolism" XP_050472087.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation" XP_050476009.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_050493545.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_050483166.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_050471695.1 10 MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041 "Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle" XP_050473333.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050484671.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_050483966.1 4 Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281 "Selenocysteine synthesis";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_050472701.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination" XP_050479465.1 29 Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167172 "Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"HIV Transcription Initiation";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome" XP_050489511.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_050491864.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050493063.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050475058.1 6 KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism" XP_050481890.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050470287.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_050481426.1 15 Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459 "Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050485041.1 3 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_050490404.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050478694.1 6 Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275 "RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation" XP_050493123.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050486867.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050477456.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050485439.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_050488872.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050477996.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_050489016.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050472737.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_050489064.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_050491408.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_050494221.1 7 Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17 "tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" XP_050485294.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050496225.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin" XP_050492047.1 6 MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6118 "Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerol degradation I";"Synthesis of PA";"Glycerol-3-phosphate shuttle" XP_050478976.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_050494370.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_050483427.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_050471581.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_050487459.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050472166.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_050482311.1 3 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_050493712.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_050490996.1 15 Reactome: R-HSA-5358752;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262 "T41 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_050493452.1 8 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_050496825.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050478757.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_050489332.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_050481231.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050489925.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050473924.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_050485764.1 3 KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis" XP_050472997.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050473327.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7589 "Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)" XP_050471260.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_050489938.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050493119.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050490122.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050478619.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050482002.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-1433559 "Neddylation";"Regulation of KIT signaling" XP_050469699.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_050489502.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_050490693.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050485261.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_050484590.1 8 Reactome: R-HSA-5659996;MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00051+5.3.1.6;Reactome: R-HSA-6791461;KEGG: 00710+5.3.1.6;KEGG: 00030+5.3.1.6;MetaCyc: PWY-1861 "RPIA deficiency: failed conversion of R5P to RU5P";"Rubisco shunt";"Pentose phosphate pathway";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of RU5P to R5P";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_050481996.1 3 Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420 "Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)" XP_050477326.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897 "Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes" XP_050475516.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_050487895.1 19 Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825 "Platelet sensitization by LDL";"LDL clearance";"VLDL clearance";"VLDL assembly";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Chylomicron clearance";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis" XP_050470241.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050471239.1 18 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"mTORC1-mediated signalling";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050496489.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_050476707.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_050482551.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050490960.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_050489537.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_050476850.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050473619.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050489457.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-1632852 "mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy" XP_050473945.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_050484984.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050491876.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_050483582.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050473069.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_050488215.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation" XP_050475199.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050470935.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050481486.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050474917.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050474996.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_050472093.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050485740.1 3 Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_050493121.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050487949.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_050493627.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050476096.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_050481313.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_050492524.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex" XP_050481881.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_050485031.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050473895.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050488613.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation" XP_050478737.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_050473376.1 12 KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1839117 "PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Rho GTPase cycle";"Human papillomavirus infection";"NRAGE signals death through JNK";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by FGFR1 in disease";"Human cytomegalovirus infection";"Signaling by cytosolic FGFR1 fusion mutants" XP_050479891.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050475556.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_050494245.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050473969.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050493708.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_050476000.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" XP_050472781.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_050470407.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_050485174.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_050484878.1 3 KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis" XP_050478804.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050482318.1 5 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_050487143.1 12 MetaCyc: PWY-6672;MetaCyc: PWY-5108;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00630+6.2.1.1 "Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Methane metabolism";"Lupulone and humulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis";"Pyruvate metabolism";"Propanoate metabolism";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism" XP_050494036.1 7 KEGG: 00730+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7185;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-7184 "Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_050486170.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050471481.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050471341.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_050493596.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050493609.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_050492496.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_050471448.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_050484102.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_050474741.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_050486026.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_050470710.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050487831.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_050488242.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex" XP_050493019.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_050477055.1 9 Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-191859;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2426168 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Circadian Clock";"snRNP Assembly";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)" XP_050485846.1 13 KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_050470691.1 33 Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_050492874.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_050486252.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_050484318.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_050493614.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_050482699.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_050485589.1 52 Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-6781827 "RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_050476361.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-428930 "G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor" XP_050495039.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_050494733.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409 "Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis" XP_050476230.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_050477447.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-2160916 "AURKA Activation by TPX2";"Hyaluronan uptake and degradation" XP_050486010.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050486848.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050483646.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050491232.1 7 MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824 "Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis" XP_050488945.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050491603.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_050475689.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_050476577.1 10 MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis IV (plant cytosol)" XP_050470034.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050478297.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin" XP_050492461.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_050485130.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949 "Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin" XP_050478283.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050478230.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050477609.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952 "HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions" XP_050471161.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050491988.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_050491261.1 3 MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581 "Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_050475472.1 5 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_050469586.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050474798.1 3 Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050484188.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050477271.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_050493110.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_050487573.1 7 Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation" XP_050493086.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579 "Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange" XP_050485655.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050492117.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_050490819.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_050476496.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050493497.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050494129.1 4 Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_050469594.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050486615.1 5 KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;MetaCyc: PWY-5531;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_050496314.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis" XP_050477289.1 6 Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210 "Mitochondrial protein import";"Oxidative phosphorylation";"ATP biosynthesis";"Cristae formation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling" XP_050487409.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_050481475.1 16 Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558 "Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"G alpha (q) signalling events";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_050484688.1 6 MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143 "Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis" XP_050490981.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_050474770.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_050493281.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_050471003.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_050472714.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_050477194.1 9 MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5484;Reactome: R-HSA-70171 "Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis" XP_050480186.1 24 Reactome: R-HSA-354192;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;Reactome: R-HSA-2730905;Reactome: R-HSA-202424;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165158;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-5218921;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1 "Integrin signaling";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Downstream TCR signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"Activation of AKT2";"Human papillomavirus infection";"FCERI mediated NF-kB activation";"VEGFR2 mediated cell proliferation";"Human immunodeficiency virus 1 infection";"RSK activation";"Human cytomegalovirus infection" XP_050487704.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050485017.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050484156.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_050487333.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_050470733.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050488540.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_050491554.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_050480825.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050486237.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" XP_050472387.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_050489157.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_050494778.1 2 Reactome: R-HSA-5655302;Reactome: R-HSA-1839117 "Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants" XP_050487742.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_050484535.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050482758.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_050479241.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_050492346.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_050482390.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050492383.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050478720.1 24 Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-190861 "COPI-mediated anterograde transport";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Recycling pathway of L1";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Gap junction assembly" XP_050486017.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050487777.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050496463.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)" XP_050469623.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050478551.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_050491743.1 4 Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1" XP_050484475.1 26 Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-380320 "Recycling pathway of L1";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes" XP_050486045.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_050486789.1 7 KEGG: 00100+1.3.1.70;MetaCyc: PWY-8026;MetaCyc: PWY-6074;MetaCyc: PWY-7154;Reactome: R-HSA-191273;Reactome: R-HSA-9022692;MetaCyc: PWY-2541 "Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Zymosterol biosynthesis";"Ergosterol biosynthesis II";"Cholesterol biosynthesis";"Regulation of MECP2 expression and activity";"Phytosterol biosynthesis (plants)" XP_050482803.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_050485803.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050477296.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_050493096.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_050478591.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050469696.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_050477658.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_050490918.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_050483781.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050469530.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050472739.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_050494763.1 2 Reactome: R-HSA-5655302;Reactome: R-HSA-1839117 "Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants" XP_050472319.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050484862.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_050494773.1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" XP_050479239.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_050489830.1 9 KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)" XP_050491443.1 10 Reactome: R-HSA-156827;Reactome: R-HSA-9648895;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-381042;Reactome: R-HSA-9633012;Reactome: R-HSA-72731;Reactome: R-HSA-382556;Reactome: R-HSA-72649 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Recycling of eIF2:GDP";"ABC-family proteins mediated transport";"Translation initiation complex formation" XP_050493084.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_050470308.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_050472881.1 5 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-212300 "DNA methylation";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA" XP_050488718.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050492184.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_050469848.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050482765.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_050481460.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" XP_050470097.1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" XP_050482816.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050493989.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_050496802.1 11 MetaCyc: PWY-6352;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1632852;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-109704 "3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Inositol phosphate metabolism";"Macroautophagy";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade" XP_050474755.1 18 Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-5689901;Reactome: R-HSA-1221632;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"Metalloprotease DUBs";"Meiotic synapsis";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint" XP_050477618.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066 "Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation" XP_050482472.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050477290.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670 "Purine metabolism";"Hedgehog 'off' state";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway" XP_050493374.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_050475763.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_050479156.1 5 KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;MetaCyc: PWY-8043 "Cysteine and methionine metabolism";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis" XP_050484829.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_050490564.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_050492342.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_050497077.1 6 Reactome: R-HSA-5654693;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-9028731;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700 "FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling" XP_050485023.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050486612.1 57 Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091 "Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells" XP_050478249.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050496365.1 9 Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-400206 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha" XP_050488753.1 4 MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate" XP_050485514.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_050485536.1 5 Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198 "Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs" XP_050484694.1 6 KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920 "Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)" XP_050472498.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050481474.1 16 Reactome: R-HSA-114604;Reactome: R-HSA-1433557;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-1660499;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-512988 "GPVI-mediated activation cascade";"Signaling by SCF-KIT";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"RET signaling";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling" XP_050472395.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050485940.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_050490721.1 5 MetaCyc: PWY-6012;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012-1;MetaCyc: PWY-6289;Reactome: R-HSA-199220 "Acyl carrier protein metabolism";"Pantothenate and CoA biosynthesis";"Acyl carrier protein activation";"Petrobactin biosynthesis";"Vitamin B5 (pantothenate) metabolism" XP_050488539.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_050475565.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_050479795.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6807505 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes" XP_050481989.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_050491487.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050496843.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_050470114.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_050479673.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" XP_050490654.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050488495.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050478813.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050488318.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_050472623.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050491989.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050491240.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation" XP_050477193.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_050471515.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_050481018.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050491699.1 6 Reactome: R-HSA-2046106;Reactome: R-HSA-1369062;Reactome: R-HSA-2046105;Reactome: R-HSA-9603798;Reactome: R-HSA-5684045;Reactome: R-HSA-390247 "alpha-linolenic acid (ALA) metabolism";"ABC transporters in lipid homeostasis";"Linoleic acid (LA) metabolism";"Class I peroxisomal membrane protein import";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Beta-oxidation of very long chain fatty acids" XP_050476594.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_050470545.1 4 KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4 "Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism" XP_050492699.1 12 MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5872;MetaCyc: PWY-6708;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5870 "Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)" XP_050469569.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_050481103.1 6 Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368 "Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation" XP_050473623.1 3 KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_050494068.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_050470158.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_050490055.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050479245.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion" XP_050478017.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050492729.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050472438.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050481039.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_050476105.1 16 Reactome: R-HSA-2046105;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-2046106;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041 "Linoleic acid (LA) metabolism";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"alpha-linolenic acid (ALA) metabolism";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis" XP_050475593.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050488229.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050475479.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_050469612.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_050487964.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_050490814.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_050474769.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_050487627.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_050480135.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_050477445.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-2160916 "AURKA Activation by TPX2";"Hyaluronan uptake and degradation" XP_050469392.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050493787.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050483063.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050485438.1 3 MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism" XP_050476969.1 4 MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6 "S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism" XP_050485047.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_050473688.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050495127.1 4 MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1 "Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism" XP_050484193.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050493141.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050474832.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050482809.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050488095.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_050470434.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050476903.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_050489038.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050485407.1 17 Reactome: R-HSA-200425;Reactome: R-HSA-163765;MetaCyc: PWY-6679;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-5743;Reactome: R-HSA-196780 "Carnitine metabolism";"ChREBP activates metabolic gene expression";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Biotin transport and metabolism" XP_050482784.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_050470719.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_050470242.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050475674.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_050486292.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_050472009.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050480274.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050486639.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050474516.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050483915.1 4 MetaCyc: PWY-8040;MetaCyc: PWY-7383;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1 "Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"D-Alanine metabolism" XP_050478724.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050471759.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_050489090.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050478084.1 4 Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_050493219.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050487045.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_050488437.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050475664.1 11 MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-3861;Reactome: R-HSA-446205;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456;KEGG: 00051+5.3.1.8 "Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Mannitol degradation II";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism" XP_050491223.1 29 Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-6782135 "RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER" XP_050479982.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_050481606.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050493161.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_050472627.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050489850.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_050483727.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050489805.1 3 KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619 "Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI" XP_050488958.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_050472585.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050493229.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_050492953.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050483791.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-5667 "Synthesis of PA";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I" XP_050482335.1 5 KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451 "Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_050472853.1 4 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_050484325.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_050483344.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050470005.1 10 MetaCyc: PWY-5497;MetaCyc: PWY-5030;MetaCyc: PWY-2201;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613 "Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Folate transformations I";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_050478113.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" XP_050480832.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_050493190.1 10 MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00240+2.1.1.45;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7187;MetaCyc: PWY-3841;Reactome: R-HSA-69205;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7199 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleosides salvage" XP_050489285.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_050482099.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_050482005.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135 "Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER" XP_050489533.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_050476876.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050494382.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_050488356.1 33 Reactome: R-HSA-69656;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-69231;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-8939236;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-69202;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-167158 "Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex" XP_050481963.1 8 MetaCyc: PWY-7524;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-2426168 "Mevalonate pathway III (archaea)";"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)" XP_050477270.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_050469462.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_050489501.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_050490473.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050487201.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_050471218.1 8 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012 "Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050486849.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050489019.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050473022.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050488265.1 7 MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25 "Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis" XP_050476687.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050486312.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288 "Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1" XP_050487283.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_050483498.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_050481674.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050494270.1 3 MetaCyc: PWY-5129;Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17 "Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism" XP_050482340.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050484007.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_050474467.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-6784531 "HCMV Late Events";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus" XP_050485691.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690 "Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events" XP_050473195.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_050488339.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_050471616.1 5 Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796 "Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation" XP_050476319.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050472730.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_050476252.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_050470768.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_050472936.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050471224.1 11 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-383280 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway" XP_050472882.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_050470608.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_050478726.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050477000.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_050494381.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_050494391.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050490800.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_050496951.1 4 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_050492774.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050486029.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_050491742.1 2 Reactome: R-HSA-2564830;Reactome: R-HSA-83936 "Cytosolic iron-sulfur cluster assembly";"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050484834.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_050480590.1 19 Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825 "VLDL assembly";"Platelet sensitization by LDL";"LDL clearance";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"LDL remodeling";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Chylomicron assembly";"Chylomicron clearance";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis" XP_050470552.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_050491644.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_050484319.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_050476107.1 16 MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;Reactome: R-HSA-2046106;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-2046105 "Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"alpha-linolenic acid (ALA) metabolism";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Linoleic acid (LA) metabolism" XP_050470447.1 29 Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823 "RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_050490408.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050473779.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050481761.1 14 Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314 "HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Polymerase switching";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex" XP_050489498.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_050486064.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_050487108.1 10 MetaCyc: PWY-5892;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5895;MetaCyc: PWY-7996;MetaCyc: PWY-5891;MetaCyc: PWY-5839;MetaCyc: PWY-5890;Reactome: R-HSA-2142789;MetaCyc: PWY-5844;MetaCyc: PWY-5849 "Menaquinol-12 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-11 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-10 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis" XP_050486423.1 56 Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-202424 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling" XP_050477607.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-111932 "Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion homeostasis";"RAF activation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB" XP_050497118.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane" XP_050486253.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_050474135.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050491828.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_050481805.1 6 MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370 "D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALT can cause Galactosemia";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism" XP_050472001.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050481904.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050479385.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_050484005.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050485025.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_050471537.1 25 Reactome: R-HSA-8936459;Reactome: R-HSA-9616222;Reactome: R-HSA-8941326;Reactome: R-HSA-8941284;Reactome: R-HSA-8951911;Reactome: R-HSA-8934593;Reactome: R-HSA-8939247;Reactome: R-HSA-8939245;Reactome: R-HSA-8877330;Reactome: R-HSA-8935964;Reactome: R-HSA-8941333;Reactome: R-HSA-8939256;Reactome: R-HSA-9018519;Reactome: R-HSA-8931987;Reactome: R-HSA-8949275;Reactome: R-HSA-8941332;Reactome: R-HSA-8939243;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-8878166;Reactome: R-HSA-8939242;Reactome: R-HSA-8941858;Reactome: R-HSA-8951936;Reactome: R-HSA-8939246;Reactome: R-HSA-8939902 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates bone development";"RUNX2 regulates chondrocyte maturation";"RUNX3 regulates RUNX1-mediated transcription";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in WNT signaling";"Estrogen-dependent gene expression";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates genes involved in cell migration";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Regulation of RUNX3 expression and activity";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX2 expression and activity" XP_050486051.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_050489106.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050476356.1 5 MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3 "Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Pyrimidine metabolism" XP_050493794.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_050473972.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050479466.1 29 Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Dual Incision in GG-NER";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_050485373.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_050476630.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" XP_050487636.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050483795.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_050486442.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050481941.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_050474560.1 6 KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-6731;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-5941 "Starch and sucrose metabolism";"Starch degradation V";"Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Glycogen degradation II" XP_050487058.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_050493774.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_050474728.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_050476234.1 5 Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656253 "Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_050478507.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation" XP_050493282.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_050490455.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050484367.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050483313.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135 "Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation" XP_050495095.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_050477067.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-111367 "RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs" XP_050493002.1 12 KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4 "Purine metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Selenate reduction";"Selenocompound metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Monobactam biosynthesis" XP_050473729.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_050480258.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_050483124.1 5 Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_050485507.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_050472283.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_050472768.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050473991.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_050493704.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_050473915.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_050477862.1 13 MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5537;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5 "Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Propanoate metabolism" XP_050483037.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases" XP_050483342.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050481962.1 8 MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-2426168 "Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)" XP_050491000.1 15 Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated" XP_050487632.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_050481233.1 33 Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276 "snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways" XP_050479672.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_050469669.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050489685.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050484908.1 7 Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133 "Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1" XP_050485678.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "Aggrephagy";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_050476059.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050489540.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_050477784.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_050470280.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050491958.1 16 Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128 "TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling" XP_050494119.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050472465.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_050487568.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050489002.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_050473982.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_050478744.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_050474000.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_050472375.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050482549.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050470466.1 6 Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900 "Disinhibition of SNARE formation";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4" XP_050484537.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050472258.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_050483563.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050477535.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050469424.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050490571.1 10 Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-6804756 "AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation" XP_050470573.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050476884.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_050474001.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_050471357.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050476678.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_050496432.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_050489886.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852 "Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Macroautophagy" XP_050492458.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_050484922.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050487576.1 7 Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105 "Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation" XP_050485863.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_050479860.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_050496487.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_050480278.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050485657.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050475462.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_050482316.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050493290.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_050480310.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_050478144.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_050485063.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050469390.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050478506.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_050482729.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050469961.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050492994.1 12 MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4 "Selenate reduction";"Selenocompound metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Purine metabolism";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism" XP_050478957.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism" XP_050481664.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050493140.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050472300.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport" XP_050481906.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050496145.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050484306.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050489968.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_050489337.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis" XP_050492355.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_050486810.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050477697.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_050493101.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_050480738.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_050485769.1 3 KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317 "Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)" XP_050484966.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_050488880.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050493945.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050477138.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_050480728.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_050478566.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050488280.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_050489274.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_050473016.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050479867.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050474563.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_050480252.1 10 Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-4661 "Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_050492932.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050487051.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation" XP_050477463.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_050485660.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6 "Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism" XP_050482629.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_050491657.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050480711.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050471222.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_050486893.1 8 Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750 "Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6" XP_050493225.1 10 KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357956;Reactome: R-HSA-5357905;KEGG: 05170+2.7.11.1 "T cell receptor signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling";"Human immunodeficiency virus 1 infection" XP_050471914.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_050474894.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_050473858.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Oxidative phosphorylation";"ATP biosynthesis";"Amino acids regulate mTORC1";"Ion channel transport";"Photosynthesis";"Transferrin endocytosis and recycling" XP_050471352.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_050490733.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050493145.1 6 MetaCyc: PWY-6368;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;Reactome: R-HSA-1660517;KEGG: 00562+3.1.3.64;KEGG: 04070+3.1.3.64 "3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_050485379.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_050491027.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_050492727.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050471860.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050473635.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695 "Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Neutrophil degranulation" XP_050483534.1 3 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_050469953.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_050472526.1 17 Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-69091 "Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching" XP_050469963.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050488174.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_050476743.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_050495607.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976 "Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols" XP_050492467.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050493802.1 14 MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788 "Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC" XP_050496695.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_050487020.1 9 Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-9656255;Reactome: R-HSA-9657050;Reactome: R-HSA-9656256;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-5649702 "Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Binding";"Defective OGG1 Localization";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_050472810.1 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_050493509.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050479856.1 4 Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_050491229.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression" XP_050476244.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_050469595.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050485046.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_050492513.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_050477464.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050474050.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050485693.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"HCMV Early Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_050485156.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050484504.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050493471.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_050482229.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_050478986.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_050473053.1 18 MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;Reactome: R-HSA-499943;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7205;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220 "Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_050471669.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050488554.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_050472243.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050484375.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_050472778.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_050485993.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_050473389.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050482555.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050484486.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_050470601.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050472138.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1" XP_050472247.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050475829.1 10 Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-3821 "Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification" XP_050475062.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050475635.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050492384.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_050478045.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy" XP_050477399.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" XP_050480270.1 24 KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5218921;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;Reactome: R-HSA-202424;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"RSK activation";"VEGFR2 mediated cell proliferation";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"RHO GTPases activate PKNs";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"Activation of AKT2";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"Downstream TCR signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of TP53 Degradation";"Thermogenesis";"CLEC7A (Dectin-1) signaling";"Relaxin signaling pathway" XP_050479547.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050482054.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050477602.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066 "Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation" XP_050493804.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_050484961.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762 "Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation" XP_050483281.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_050471250.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050490299.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_050480788.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050489327.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642 "Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_050470326.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050472939.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050482008.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_050488357.1 33 Reactome: R-HSA-112382;Reactome: R-HSA-69656;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-69231;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-8939236;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-69202 "Formation of RNA Pol II elongation complex";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition" XP_050476875.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050480774.1 17 Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-174414;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-69183 "Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Processive synthesis on the C-strand of the telomere";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand" XP_050484238.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050472051.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050488492.1 57 Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442 "Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Hedgehog 'on' state";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs" XP_050489480.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050482420.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_050487014.1 12 MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4 "Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism" XP_050483353.1 5 KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3 "Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)" XP_050482833.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_050484406.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_050493284.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_050475767.1 2 Reactome: R-HSA-975634;Reactome: R-HSA-192456 "Retinoid metabolism and transport";"Digestion of dietary lipid" XP_050470534.1 4 Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030 "Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis" XP_050486318.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_050486649.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050475642.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050489046.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_050488239.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050494017.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_050477644.1 9 Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-3642279 "Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"TGFBR2 MSI Frameshift Mutants in Cancer" XP_050494804.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_050470774.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_050473027.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050477807.1 3 MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996 "Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)" XP_050496927.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050482514.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_050481872.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_050485999.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_050472740.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_050485253.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050488763.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050476545.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_050474915.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050472750.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_050486460.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_050472370.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050493221.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_050483613.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-139915 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria" XP_050471217.1 8 KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection" XP_050481877.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050496403.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050497053.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes" XP_050490812.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_050474814.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_050485749.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_050476779.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050478207.1 16 Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553 "Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Neddylation";"Regulation of expression of SLITs and ROBOs" XP_050497048.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050489287.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_050477269.1 9 Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-68962 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Polymerase switching";"DNA replication initiation";"Activation of the pre-replicative complex" XP_050496162.1 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" XP_050479226.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_050480959.1 6 MetaCyc: PWY-5497;MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442 "Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis" XP_050475195.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_050496836.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050492457.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050488176.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_050489644.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_050470117.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_050494058.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_050483458.1 13 MetaCyc: PWY-5537;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690 "Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)" XP_050470237.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050470718.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation" XP_050487480.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_050476954.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_050471851.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_050493667.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050474667.1 4 Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-176187 "Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress" XP_050477413.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050486619.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_050490580.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation" XP_050477034.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_050470693.1 33 Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-159231 "SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_050474508.1 10 KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Other glycan degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_050491461.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_050494651.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409 "Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis" XP_050487924.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_050472127.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" XP_050472809.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_050473950.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_050482878.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050492897.1 6 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-204005 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"COPII-mediated vesicle transport" XP_050489988.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_050491921.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_050494006.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_050470304.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050472149.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_050471092.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050474677.1 14 Reactome: R-HSA-141444;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-9648025;Reactome: R-HSA-380259;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-8854518 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"AURKA Activation by TPX2" XP_050469817.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050486788.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050475948.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050493711.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_050486853.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050491820.1 33 Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-159231 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_050489778.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050470381.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050484515.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050479637.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_050478590.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050478601.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050472027.1 9 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-5218920;Reactome: R-HSA-2871796;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated vascular permeability";"FCERI mediated MAPK activation";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_050469748.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-204005 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPII-mediated vesicle transport" XP_050484880.1 3 Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271 "GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_050495415.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis" XP_050471920.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050473941.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_050487019.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_050478481.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050484251.1 7 Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798 "HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell" XP_050478814.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050474754.1 18 Reactome: R-HSA-5693565;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-5689901;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"Metalloprotease DUBs";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_050484381.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_050492521.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050483503.1 3 Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078 "GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)" XP_050485491.1 12 MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-9620244 "Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"Long-term potentiation" XP_050478387.1 8 Reactome: R-HSA-6787639;MetaCyc: PWY-5739;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-7573 "GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis" XP_050479929.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_050493955.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050480133.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_050472135.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1" XP_050491286.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_050491189.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_050492965.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_050471396.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_050481681.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050474217.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-3238698 "Neutrophil degranulation";"WNT ligand biogenesis and trafficking" XP_050473162.1 9 Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-442982 "Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"Neurexins and neuroligins";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor" XP_050474668.1 4 Reactome: R-HSA-111465;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-176187 "Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress" XP_050496413.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662 "TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism" XP_050493612.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_050483799.1 10 Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264 "Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation" XP_050488027.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050491478.1 24 Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-190861 "COPI-mediated anterograde transport";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Recycling pathway of L1";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Gap junction assembly" XP_050478459.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050475083.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_050480766.1 17 Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER" XP_050482003.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER" XP_050485186.1 17 MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-7383;MetaCyc: PWY-5392;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00270+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622 "Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Methylaspartate cycle";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)" XP_050493747.1 7 Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484 "Gluconeogenesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_050492364.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_050470605.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050478977.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050491873.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050485013.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050477943.1 2 Reactome: R-HSA-5633231;Reactome: R-HSA-446193 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_050482626.1 7 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22 "Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_050470274.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050490000.1 3 Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110357 "Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1" XP_050492123.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_050477458.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050488461.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050481644.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_050477468.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_050492313.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050481175.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050480547.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_050471264.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_050484015.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050481315.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-450520;Reactome: R-HSA-69273;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-9634638 "MAPK6/MAPK4 signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_050477311.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_050492591.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050475481.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-442720 "Hedgehog 'off' state";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_050488881.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050492278.1 4 Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69202 "Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition" XP_050476227.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_050480991.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression" XP_050474561.1 6 MetaCyc: PWY-6731;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-7238 "Starch degradation III";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II" XP_050481756.1 14 Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862 "Translesion synthesis by REV1";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Polymerase switching";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK" XP_050480993.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168 "PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)" XP_050487620.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_050487708.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_050480755.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation" XP_050485965.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829 "COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_050495810.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409 "Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis" XP_050493139.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050486300.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_050480795.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_050481507.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_050489859.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_050475181.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_050481202.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050484970.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription" XP_050479271.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779 "RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_050487054.1 16 Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176412 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C" XP_050478727.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_050479223.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_050493254.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050481169.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050482169.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050487461.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050472473.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_050471632.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080 "Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)" XP_050474076.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_050483936.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-4793954;MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)" XP_050482276.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050497083.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_050493401.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050478259.1 8 KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1 "Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis" XP_050481649.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_050480374.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_050482964.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050470073.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050486636.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050483084.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation" XP_050492477.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050492561.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_050481012.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050487267.1 4 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;Reactome: R-HSA-2408557 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis" XP_050492237.1 12 KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932 "Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction" XP_050480257.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_050482914.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_050470805.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214 "Macroautophagy";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs" XP_050486933.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane" XP_050494199.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_050471751.1 10 Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-111458 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome" XP_050483286.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_050484547.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_050473191.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_050484248.1 7 Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-373080 "Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)" XP_050494126.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050481323.1 17 Reactome: R-HSA-112382;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167290;KEGG: 05235+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167152 "Formation of RNA Pol II elongation complex";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat" XP_050490042.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050486283.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_050493069.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050485449.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_050488056.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_050476384.1 14 Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity" XP_050482648.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_050491940.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_050484626.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050477223.1 8 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_050480818.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050495074.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050473780.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050486967.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050480303.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_050488382.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_050491214.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-389513 "AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling" XP_050493391.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_050486452.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050488563.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_050487968.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_050493091.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_050475309.1 6 KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817 "One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_050490907.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" XP_050492538.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050485251.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050492372.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_050475475.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_050475497.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_050487878.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"Degradation of DVL";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D" XP_050487278.1 57 Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-532668;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1" XP_050491444.1 10 Reactome: R-HSA-156827;Reactome: R-HSA-9648895;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72731;Reactome: R-HSA-382556;Reactome: R-HSA-72649 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Recycling of eIF2:GDP";"ABC-family proteins mediated transport";"Translation initiation complex formation" XP_050493506.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_050482094.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_050480507.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_050491224.1 29 Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73779 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_050476573.1 14 Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;MetaCyc: PWY-6453 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Synthesis of PC";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Synthesis of PE";"Anandamide biosynthesis II";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis" XP_050471897.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050485154.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050483405.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050492954.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050482760.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_050480124.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_050486798.1 5 Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409 "Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation" XP_050485352.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050471639.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_050479592.1 8 Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111458 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"Formation of apoptosome" XP_050493666.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050496609.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050476716.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050489334.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"Kinesins";"MHC class II antigen presentation" XP_050469600.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050487266.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050487753.1 52 Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-76071;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242 "mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_050469916.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_050487694.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050478381.1 5 MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)" XP_050472204.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_050489867.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050490457.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050487810.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050497084.1 7 Reactome: R-HSA-2173795;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939;Reactome: R-HSA-110362;Reactome: R-HSA-3108214 "Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA damage response and repair proteins" XP_050481794.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_050485732.1 10 MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-8004;Reactome: R-HSA-70263;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;KEGG: 00010+2.7.2.3 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis" XP_050470325.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050484693.1 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway" XP_050476683.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-611105 "Mitochondrial protein import";"Respiratory electron transport" XP_050470079.1 14 Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-113418 "TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex" XP_050497104.1 8 KEGG: 00030+2.2.1.2;MetaCyc: PWY-1861;Reactome: R-HSA-71336;MetaCyc: PWY-5723;Reactome: R-HSA-6791462;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;Reactome: R-HSA-8950505 "Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_050479554.1 9 Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" XP_050493600.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_050493341.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane" XP_050489683.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint" XP_050482380.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_050474998.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_050469911.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_050472652.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_050493613.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_050475014.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_050471256.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_050472237.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_050494332.1 3 Reactome: R-HSA-1660499;KEGG: 04660+2.7.10.2;Reactome: R-HSA-111465 "Synthesis of PIPs at the plasma membrane";"T cell receptor signaling pathway";"Apoptotic cleavage of cellular proteins" XP_050469958.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050486420.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050487980.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050478715.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050473616.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050494772.1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" XP_050490306.1 5 KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_050487046.1 5 Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-918233 "TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway" XP_050491078.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_050477999.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_050488647.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050491410.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_050474389.1 11 MetaCyc: PWY-6538;MetaCyc: PWY-5497;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-6608;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6999;MetaCyc: PWY-6596;MetaCyc: PWY-6606;KEGG: 00232+1.17.3.2;KEGG: 00230+1.17.1.4+1.17.3.2 "Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Drug metabolism - other enzymes";"Theophylline degradation";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Caffeine metabolism";"Purine metabolism" XP_050492924.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050491624.1 5 Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-4420097 "p38MAPK events";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway" XP_050487374.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050485872.1 14 Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-1474228;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"Degradation of the extracellular matrix";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells" XP_050490370.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_050483320.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation" XP_050492514.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_050488373.1 18 Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4 "Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism" XP_050470410.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_050476908.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050486959.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_050492750.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway" XP_050470697.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050469775.1 28 Reactome: R-HSA-3371453;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5696395;Reactome: R-HSA-110314 "Regulation of HSF1-mediated heat shock response";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"HSF1 activation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex" XP_050487747.1 52 Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-73980;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-76071;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-167152;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-5617472 "RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Termination";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_050491360.1 26 Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-389977 "Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"Recycling pathway of L1";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway" XP_050494193.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_050475662.1 11 MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-3861;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;KEGG: 00051+5.3.1.8 "Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism" XP_050482270.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050493595.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_050484256.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050483617.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_050486653.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway" XP_050471067.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050474895.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_050496461.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050473223.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565 "Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_050486533.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_050485753.1 7 KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483191;MetaCyc: PWY-3385;MetaCyc: PWY-7886;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-7818 "Glycerophospholipid metabolism";"Synthesis of PC";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)" XP_050486856.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_050487842.1 11 Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_050492714.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" XP_050483789.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7411 "Synthesis of PA";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)" XP_050491847.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_050472146.1 1 Reactome: R-HSA-417973 "Adenosine P1 receptors" XP_050490244.1 24 Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-9009391;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-416476 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events" XP_050472606.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_050494100.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050476094.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_050476235.1 16 Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1963640;Reactome: R-HSA-1251985;Reactome: R-HSA-1250347;Reactome: R-HSA-1250342;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"GRB2 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB4";"PI3K events in ERBB2 signaling" XP_050473797.1 3 Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757 "HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation" XP_050472188.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_050472628.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050493549.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_050475590.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050480358.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050477285.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Purine metabolism";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_050476359.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)" XP_050491799.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050483408.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050478265.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050480337.1 2 Reactome: R-HSA-189085;Reactome: R-HSA-2129379 "Digestion of dietary carbohydrate";"Molecules associated with elastic fibres" XP_050487056.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_050488713.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050494459.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_050478844.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565 "Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_050479125.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050477264.1 9 Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-69166 "DNA replication initiation";"Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate" XP_050470952.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_050494372.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_050493094.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_050493088.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_050487733.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_050477590.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5576892 "Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation" XP_050470178.1 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" XP_050488043.1 16 Reactome: R-HSA-70263;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-1622;MetaCyc: PWY-7124;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7218 "Gluconeogenesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Formaldehyde assimilation I (serine pathway)";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_050493525.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_050474806.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050484832.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_050476945.1 8 Reactome: R-HSA-1855183;KEGG: 00562+5.5.1.4;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-6372;MetaCyc: PWY-2301;MetaCyc: PWY-4661;MetaCyc: PWY-6664 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis" XP_050477787.1 12 Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events" XP_050471872.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050476521.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" XP_050475250.1 7 Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711 "Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events" XP_050478743.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_050485878.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_050487040.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_050496889.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_050482794.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_050476093.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_050492796.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" XP_050470469.1 10 Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162 "RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape" XP_050486926.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism" XP_050485555.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_050476563.1 2 Reactome: R-HSA-804914;Reactome: R-HSA-9029569 "Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_050486715.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_050472097.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_050490447.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050472390.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_050492485.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_050490070.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_050491950.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_050470159.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_050470532.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_050477146.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_050481173.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050475402.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_050475105.1 3 Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490 "Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation" XP_050485610.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602 "Fatty acid elongation";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_050492835.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050475059.1 6 KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock" XP_050497091.1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453 "Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis" XP_050493108.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_050480670.1 57 Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276 "Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Neddylation";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_050472664.1 17 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-72649 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Translation initiation complex formation" XP_050495130.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050483073.1 8 KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1 "Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis" XP_050469950.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050496213.1 4 Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568 "ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"Attenuation phase" XP_050493129.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050483322.1 9 Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948 "Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants" XP_050472554.1 3 KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_050487244.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974 "Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA" XP_050472769.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050493791.1 13 Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-8856828 "VLDLR internalisation and degradation";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"Clathrin-mediated endocytosis" XP_050470861.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_050471514.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050496988.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_050485635.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_050486081.1 42 KEGG: 00592+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-7216;MetaCyc: PWY-5789;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-5138;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-7778;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-6945;MetaCyc: PWY-7779;MetaCyc: PWY-7007;KEGG: 00410+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-7401;KEGG: 00623+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-6883;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7606;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-6944;MetaCyc: PWY-1361;MetaCyc: PWY-5109;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-7726 "alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Butanoate metabolism";"Fatty acid degradation";"Fatty acid degradation";"Fatty acid elongation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Tryptophan metabolism";"Butanoate metabolism";"Pyruvate fermentation to butanol I";"2-methylpropene degradation";"Phenylalanine metabolism";"Fatty acid salvage";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl tert-butyl ether degradation";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Aminobenzoate degradation";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Toluene degradation";"Caprolactam degradation";"Carbon fixation pathways in prokaryotes";"Lysine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to butanol II (engineered)";"Geraniol degradation";"Spodoptera littoralis pheromone biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Limonene and pinene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Androstenedione degradation";"Benzoyl-coa degradation I (aerobic)";"Fermentation to 2-methylbutanoate";"Benzoate degradation";"Pyruvate fermentation to hexanol (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_050481095.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050478593.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050488822.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050495839.1 21 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-6545;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7221;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7219;MetaCyc: PWY-7205 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"CMP phosphorylation" XP_050497028.1 14 MetaCyc: PWY-5101;MetaCyc: PWY-5104;MetaCyc: PWY-5057;MetaCyc: PWY-7767;MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;KEGG: 00966+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5076;Reactome: R-HSA-70895;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103 "L-isoleucine biosynthesis II";"L-isoleucine biosynthesis IV";"L-valine degradation II";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"Glucosinolate biosynthesis";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V";"L-leucine degradation III";"Branched-chain amino acid catabolism";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III" XP_050485521.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050484246.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050488812.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_050485027.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050486001.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_050482159.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050478568.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050477150.1 17 MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6627;MetaCyc: PWY-6608;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6644 "Guanine and guanosine salvage";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Purine catabolism";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Fluoroacetate and fluorothreonine biosynthesis" XP_050490818.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_050482419.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_050490971.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_050479890.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050479338.1 26 Reactome: R-HSA-3371568;Reactome: R-HSA-8941856;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-400253 "Attenuation phase";"RUNX3 regulates NOTCH signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"Circadian Clock" XP_050487984.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050480810.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050494378.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_050479633.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" XP_050489865.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_050473722.1 5 KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181 "Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism" XP_050480783.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_050473781.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050472523.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658 "COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization" XP_050476568.1 8 Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-111458;Reactome: R-HSA-8953750 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"Formation of apoptosome";"Transcriptional Regulation by E2F6" XP_050470314.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050488866.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050474005.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_050485389.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050490627.1 5 KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895 "Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency" XP_050490816.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_050474836.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_050483749.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050473615.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050492512.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_050483628.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_050487572.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation" XP_050479469.1 3 KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_050496610.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050472207.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_050480913.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050474720.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_050474562.1 6 KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-6731;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-5941 "Starch and sucrose metabolism";"Starch degradation V";"Starch degradation III";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II" XP_050490988.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_050475110.1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" XP_050487483.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_050474771.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_050484770.1 6 MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6922 "L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_050487745.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050476229.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_050470008.1 4 MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-7285;MetaCyc: PWY-6829 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis";"Trna methylation (yeast)" XP_050480635.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_050472883.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_050486568.1 52 Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091 "Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells" XP_050488148.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050489465.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050474371.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_050487699.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050477888.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_050479985.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050494204.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_050486016.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050478197.1 10 MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397 "UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis" XP_050482172.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050473922.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_050470214.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_050479600.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050487460.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050486390.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050470377.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050483438.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_050473905.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050483524.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230 "RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA" XP_050485656.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050487923.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC" XP_050492574.1 11 Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" XP_050471847.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050484146.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050494212.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862 "Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK" XP_050480080.1 9 MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664 "Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II" XP_050491938.1 11 Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Ub-specific processing proteases";"Transcription of the HIV genome";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_050482623.1 7 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22 "Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_050493124.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050476972.1 4 KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_050474497.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050479520.1 33 Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168325 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis" XP_050478471.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050478821.1 14 Reactome: R-HSA-500657;Reactome: R-HSA-4086398;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-434316;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-399997;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-418217 "Presynaptic function of Kainate receptors";"Ca2+ pathway";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Acetylcholine regulates insulin secretion";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G beta:gamma signalling through PLC beta" XP_050469525.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050486053.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508 "Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_050485537.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_050471060.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466 "Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis" XP_050481993.1 3 MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048 "Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG" XP_050492391.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050484638.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_050474058.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_050493430.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_050489196.1 56 Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome" XP_050493090.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_050488191.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050487458.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050493380.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_050490401.1 13 Reactome: R-HSA-937042;Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325 "IRAK2 mediated activation of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex" XP_050479382.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_050475212.1 9 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection" XP_050496614.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050492124.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_050477812.1 3 MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996 "Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)" XP_050482483.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_050483530.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050496521.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050494852.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_050488879.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050477517.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050495046.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_050471866.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" XP_050478486.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-196025 "Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions" XP_050490360.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050491076.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050485406.1 17 Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-6679;Reactome: R-HSA-163765;Reactome: R-HSA-200425 "Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Carnitine metabolism" XP_050489736.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_050487705.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_050479831.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050496066.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108 "Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis" XP_050475173.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050481013.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050470908.1 13 MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-7736 "Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis" XP_050486648.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050475012.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_050478595.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050488374.1 18 KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416 "Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Synthesis of PA";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_050491749.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_050491961.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050477225.1 8 Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Activation of RAC1";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_050481796.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_050489076.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_050481876.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_050482491.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_050469625.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050476360.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-416476 "Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events" XP_050490998.1 15 Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated" XP_050469558.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050484848.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_050486677.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050474605.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050477754.1 16 Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-8951664;Reactome: R-HSA-167290;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-75955 "HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Neddylation";"Pausing and recovery of HIV elongation";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation" XP_050496897.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_050494760.1 2 Reactome: R-HSA-5655302;Reactome: R-HSA-1839117 "Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants" XP_050488957.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_050482546.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050491834.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050475801.1 8 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_050491956.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_050478548.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_050493664.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050475584.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_050477366.1 5 Reactome: R-HSA-196843;MetaCyc: PWY-6168;MetaCyc: PWY-7863;KEGG: 00740+2.7.1.26;MetaCyc: PWY-5523 "Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis";"Riboflavin metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)" XP_050489484.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_050496585.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_050479976.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827 "Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_050478919.1 7 Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-8950505;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-5620922 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium" XP_050482444.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050482279.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050472131.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase" XP_050473832.1 31 Reactome: R-HSA-9029558;MetaCyc: PWY-8012;MetaCyc: PWY-7858;MetaCyc: PWY-5973;MetaCyc: PWY-5989;MetaCyc: PWY-5142;MetaCyc: PWY-4381;MetaCyc: PWY-7723;MetaCyc: PWY-5994;Reactome: R-HSA-199220;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-8049;MetaCyc: PWY-5966-1;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-6113;Reactome: R-HSA-75105;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6519;Reactome: R-HSA-163765;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-5367;MetaCyc: PWY-5366;MetaCyc: PWY-7664;MetaCyc: PWYG-321;MetaCyc: PWY-6799;MetaCyc: PWY-7746;MetaCyc: PWY-7663;MetaCyc: PWY-6282 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mupirocin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Cis-vaccenate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Biotin metabolism";"8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Petroselinate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis IV (anaerobic)";"";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mycobacterial sulfolipid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)" XP_050490980.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_050476795.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050491392.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_050472139.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164 "MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade" XP_050485390.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050479150.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_050492573.1 11 Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579 "Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange" XP_050481037.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_050476315.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050482482.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_050475677.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_050482780.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_050479148.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_050471295.1 8 Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885 "Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins" XP_050473939.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_050475961.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_050472267.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050486000.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_050471640.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_050491741.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050493230.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_050474215.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-6798695 "WNT ligand biogenesis and trafficking";"Neutrophil degranulation" XP_050492528.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050487487.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_050494246.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050482559.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_050487784.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050493472.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_050490597.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_050487707.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_050474052.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050493288.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_050481322.1 17 Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167290;KEGG: 05235+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-112382;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_050479806.1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-112043 "Ion homeostasis";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events" XP_050473402.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050484842.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_050483039.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_050476785.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_050485827.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_050473252.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050481444.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_050470320.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050470450.1 29 Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-167160 "Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_050486167.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels" XP_050475030.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_050497130.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050493232.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_050497061.1 22 MetaCyc: PWY-8013;MetaCyc: PWY-6142;Reactome: R-HSA-6798695;KEGG: 00030+5.3.1.9;MetaCyc: PWY-6992;MetaCyc: PWY-7347;MetaCyc: PWY-621;KEGG: 00520+5.3.1.9;Reactome: R-HSA-70263;KEGG: 00500+5.3.1.9;MetaCyc: PWY-622;MetaCyc: PWY-6981;MetaCyc: PWY-5514;MetaCyc: PWY-5659;MetaCyc: PWY-5384;Reactome: R-HSA-5628897;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-3801;MetaCyc: PWY-5054;MetaCyc: PWY-7238;KEGG: 00010+5.3.1.9 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Neutrophil degranulation";"Pentose phosphate pathway";"1,5-anhydrofructose degradation";"Sucrose biosynthesis III";"Sucrose degradation III (sucrose invertase)";"Amino sugar and nucleotide sugar metabolism";"Gluconeogenesis";"Starch and sucrose metabolism";"Starch biosynthesis";"Chitin biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"GDP-mannose biosynthesis";"Sucrose degradation IV (sucrose phosphorylase)";"TP53 Regulates Metabolic Genes";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Sucrose degradation II (sucrose synthase)";"D-sorbitol biosynthesis I";"Sucrose biosynthesis II";"Glycolysis / Gluconeogenesis" XP_050492998.1 12 Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25 "Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction";"Purine metabolism" XP_050479802.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398 "DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Ca2+ pathway" XP_050484473.1 26 Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"HCMV Early Events" XP_050486793.1 4 MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1 "Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism" XP_050471416.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_050486342.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_050474015.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_050496922.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050487830.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_050490703.1 4 Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_050483380.1 20 KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340 "alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)" XP_050477906.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168325 "SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis" XP_050488316.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050475190.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1" XP_050486973.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050485378.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_050494014.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_050491853.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_050471428.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_050480815.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050486925.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism" XP_050481990.1 3 Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420 "Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)" XP_050477226.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159 "Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling" XP_050477056.1 9 Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-191859;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2426168 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Circadian Clock";"snRNP Assembly";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)" XP_050475150.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050482393.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_050492362.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_050475567.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_050476913.1 12 MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4 "Assimilatory sulfate reduction III";"Sulfur metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Selenate reduction";"Selenocompound metabolism" XP_050482026.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050469433.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050486396.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050482239.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_050485148.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_050489779.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050483925.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_050491445.1 2 Reactome: R-HSA-8934593;Reactome: R-HSA-69231 "Regulation of RUNX1 Expression and Activity";"Cyclin D associated events in G1" XP_050492350.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_050475349.1 4 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_050475482.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_050494208.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_050470531.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_050469401.1 4 Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping" XP_050496435.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_050470887.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_050472010.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050476592.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_050489323.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-212676 "Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle" XP_050470139.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050486262.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_050472818.1 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_050492443.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_050485300.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050480883.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_050478390.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_050469457.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050496587.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_050471817.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050494064.1 5 Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253 "Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_050496965.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_050495532.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026 "Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_050481799.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_050485345.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050481329.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_050487886.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050470624.1 7 KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12 "Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)" XP_050472234.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_050481162.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050486438.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050470315.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050496856.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_050481461.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_050486692.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050486851.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050494002.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_050486549.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_050494223.1 7 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" XP_050482028.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050496821.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050489050.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_050477080.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050474430.1 9 Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475 "Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_050481298.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050474721.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_050487577.1 7 Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation" XP_050480827.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_050481988.1 3 MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048 "Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG" XP_050491750.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_050484686.1 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_050480323.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050482763.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050479799.1 13 Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509 "Ca2+ pathway";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling" XP_050477087.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_050485165.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050470553.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_050496357.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_050477466.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_050471065.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050479914.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050475056.1 6 Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16 "Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050493515.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_050477885.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_050477259.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_050482101.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_050477599.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050474631.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" XP_050473350.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050483470.1 13 MetaCyc: PWY-6969;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-5537 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V" XP_050471005.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_050490566.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_050496485.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_050491423.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_050494334.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_050494035.1 11 MetaCyc: PWY-5123;MetaCyc: PWY-7524;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7560;MetaCyc: PWY-922;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7102;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-191273 "Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway III (archaea)";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis" XP_050476155.1 4 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482;Reactome: R-HSA-8849175 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Threonine catabolism" XP_050478001.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_050488044.1 16 MetaCyc: PWY-1622;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-7124;KEGG: 00010+4.2.1.11;KEGG: 00680+4.2.1.11;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-8004 "Formaldehyde assimilation I (serine pathway)";"Glycerol degradation to butanol";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I" XP_050470339.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050492045.1 6 MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6118 "Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol degradation I";"Triglyceride catabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle" XP_050494067.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_050470662.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050488430.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_050474179.1 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471;Reactome: R-HSA-196741 "Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_050472378.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050471764.1 5 KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39 "Arginine biosynthesis";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism" XP_050475043.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050475552.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_050475176.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050493703.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_050485701.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_050483127.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050482993.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050484560.1 26 Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497 "HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_050493758.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_050492456.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_050494041.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_050491809.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_050479584.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050477710.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050475480.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" XP_050486634.1 14 MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053 "Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis II" XP_050478621.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050483009.1 5 MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_050493849.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_050493868.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases" XP_050476745.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_050496072.1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" XP_050470855.1 9 KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315 "Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol" XP_050482873.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_050474421.1 7 KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2 "Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis" XP_050485650.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527 "Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation" XP_050476579.1 10 KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861 "Galactose metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_050482067.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_050490687.1 12 Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"ISG15 antiviral mechanism";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050487965.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_050489007.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050478379.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_050469453.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_050485445.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_050490268.1 6 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-5269;MetaCyc: PWY-5668;MetaCyc: PWY-7817;KEGG: 00564+2.7.8.5 "Synthesis of PG";"Synthesis of PA";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism" XP_050475168.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050484380.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_050473390.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050496591.1 6 MetaCyc: PWY-6906;MetaCyc: PWY-7395;MetaCyc: PWY-7077;KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25 "Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism" XP_050482119.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050488434.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins" XP_050494220.1 7 Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17 "tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" XP_050475308.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_050481205.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050472080.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_050480962.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_050475082.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_050470007.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_050470919.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050470077.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050490016.1 15 Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-176034;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Interactions of Tat with host cellular proteins";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation" XP_050473157.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050482206.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_050487722.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" XP_050484402.1 9 Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616 "CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication" XP_050484019.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_050483437.1 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_050477846.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_050496486.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_050496381.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050475656.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_050485520.1 13 Reactome: R-HSA-2214320;Reactome: R-HSA-419037;Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-1650814;Reactome: R-HSA-186797 "Anchoring fibril formation";"NCAM1 interactions";"Collagen chain trimerization";"Crosslinking of collagen fibrils";"Collagen degradation";"Laminin interactions";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Extracellular matrix organization";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF" XP_050485994.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_050473106.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050491703.1 4 MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662 "Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism" XP_050476786.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_050478474.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050470167.1 5 Reactome: R-HSA-389661;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853 "Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)" XP_050492352.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_050493379.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050477671.1 33 KEGG: 00260+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-6313;MetaCyc: PWY-7013;MetaCyc: PWY-7111;MetaCyc: PWY-6333;MetaCyc: PWY-5079;KEGG: 00626+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5751;MetaCyc: PWY-5480;MetaCyc: PWY-6342;MetaCyc: PWY-5082;MetaCyc: PWY-5486;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-7396;MetaCyc: PWY-6587;KEGG: 00071+1.1.1.1;MetaCyc: PWY-1801;KEGG: 00625+1.1.1.1;KEGG: 00010+1.1.1.1;KEGG: 00592+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-6802;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00680+1.1.1.284;MetaCyc: PWY-3162;MetaCyc: PWY-6871;MetaCyc: PWY-5057 "Glycine, serine and threonine metabolism";"Retinol metabolism";"L-leucine degradation III";"Serotonin degradation";"(S)-propane-1,2-diol degradation";"Pyruvate fermentation to isobutanol (engineered)";"Acetaldehyde biosynthesis I";"L-phenylalanine degradation III";"Naphthalene degradation";"Drug metabolism - cytochrome P450";"Chitin degradation to ethanol";"Phenylethanol biosynthesis";"Pyruvate fermentation to ethanol I";"Noradrenaline and adrenaline degradation";"L-methionine degradation III";"Pyruvate fermentation to ethanol II";"Metabolism of xenobiotics by cytochrome P450";"Protein S-nitrosylation and denitrosylation";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol III";"Fatty acid degradation";"Formaldehyde oxidation II (glutathione-dependent)";"Chloroalkane and chloroalkene degradation";"Glycolysis / Gluconeogenesis";"alpha-Linolenic acid metabolism";"Ethanol oxidation";"Salidroside biosynthesis";"Tyrosine metabolism";"L-isoleucine degradation II";"Methane metabolism";"L-tryptophan degradation V (side chain pathway)";"3-methylbutanol biosynthesis (engineered)";"L-valine degradation II" XP_050474804.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050478383.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050485476.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050481813.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"UCH proteinases";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin" XP_050482441.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050488667.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050487015.1 12 MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053 "Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II" XP_050493122.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050481705.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_050483410.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050470700.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050479998.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_050479842.1 1 MetaCyc: PWY-6938 "NADH repair" XP_050475129.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050478256.1 8 KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1 "Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism" XP_050476169.1 14 MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51 "Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism" XP_050476877.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050482954.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_050477442.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050486168.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050483600.1 14 Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955 "Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation" XP_050489675.1 4 Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-186763 "Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1";"Downstream signal transduction" XP_050487481.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_050475895.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050482735.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_050479084.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050472197.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" XP_050484277.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050490527.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050475831.1 10 MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;Reactome: R-HSA-70370 "D-galactose detoxification";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism" XP_050491740.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050471871.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_050484750.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050492116.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes" XP_050494336.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_050485455.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050483383.1 20 MetaCyc: PWY-5136;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6 "Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism" XP_050485681.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_050473964.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050482041.1 3 MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141 "Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_050484907.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-1362300;Reactome: R-HSA-69231 "G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1" XP_050480117.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050486590.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_050483785.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-6453 "Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis" XP_050470379.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050482213.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_050471808.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_050491233.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469 "Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis" XP_050475748.1 7 Reactome: R-HSA-3214842;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-983231;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886 "HDMs demethylate histones";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Factors involved in megakaryocyte development and platelet production";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" XP_050481096.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050479353.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050486031.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_050488573.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_050492126.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_050481995.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_050474105.1 6 Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-913709;MetaCyc: PWY-7433 "Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation" XP_050479386.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_050487335.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_050488868.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050478295.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_050477540.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_050492389.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Macroautophagy";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_050478305.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050478100.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_050480587.1 8 KEGG: 00250+4.3.2.1;MetaCyc: PWY-4983;MetaCyc: PWY-5154;MetaCyc: PWY-4984;MetaCyc: PWY-5;KEGG: 00220+4.3.2.1;Reactome: R-HSA-70635;MetaCyc: PWY-7400 "Alanine, aspartate and glutamate metabolism";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Canavanine biosynthesis";"Arginine biosynthesis";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)" XP_050478602.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050474797.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050485689.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids" XP_050480103.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_050473021.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050478055.1 3 Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989 "TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" XP_050477095.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_050481974.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050481435.1 15 Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607 "Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends" XP_050480316.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050493512.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_050476719.1 6 Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-191859 "SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly" XP_050485663.1 11 Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-112382 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex" XP_050477773.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050486805.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-68952 "Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Polymerase switching";"Activation of the pre-replicative complex";"DNA replication initiation" XP_050491705.1 4 KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_050478858.1 11 Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection";"Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection";"IRF3-mediated induction of type I IFN";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_050483467.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_050489823.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_050489939.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050476847.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050484855.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones" XP_050489167.1 13 MetaCyc: PWY-6351;Reactome: R-HSA-2029485;Reactome: R-HSA-2424491;Reactome: R-HSA-9027277;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Role of phospholipids in phagocytosis";"DAP12 signaling";"Erythropoietin activates Phospholipase C gamma (PLCG)";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_050494371.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_050475036.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050476241.1 4 Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-9615017 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_050481128.1 6 Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368 "Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation" XP_050475116.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation" XP_050482385.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050486394.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_050471531.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050484879.1 3 KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271 "Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_050478618.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_050489701.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_050471507.1 3 KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562 "Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria" XP_050485152.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050493287.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_050486512.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050470574.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050483311.1 9 Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948 "Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants" XP_050494343.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050485690.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase" XP_050491821.1 33 Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-141444 "Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050471953.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-389661 "Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation" XP_050472775.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_050481617.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_050477774.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050486927.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism" XP_050470207.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050480957.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050470421.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_050495640.1 10 Reactome: R-HSA-2894862;Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_050472000.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050471798.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050490570.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_050483033.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_050486972.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050483282.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_050479092.1 7 KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11 "Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_050485770.1 3 KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis" XP_050471004.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_050471245.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity" XP_050473826.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_050493950.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050492838.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_050472284.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_050474556.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050491007.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050484586.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_050483724.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050471226.1 11 Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253 "Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock" XP_050483133.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050477282.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" XP_050478807.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050493768.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050486393.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050482661.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050480255.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_050479091.1 7 MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367 "2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" XP_050473343.1 8 MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_050487631.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_050484228.1 3 Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_050473795.1 3 Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690 "Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events" XP_050477256.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_050475246.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277 "Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex" XP_050483415.1 18 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7226 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_050486247.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050480616.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050473338.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050478725.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_050471095.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050473621.1 3 KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_050481975.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "Neutrophil degranulation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_050482180.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050470251.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050490026.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_050491552.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050483086.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress" XP_050476487.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050470695.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050493099.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_050469397.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050482271.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050485659.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050485405.1 17 MetaCyc: PWY-5789;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Candicidin biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis" XP_050489493.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_050487357.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050476915.1 12 MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4 "Selenate reduction";"Selenocompound metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Purine metabolism";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism" XP_050487865.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_050472147.1 6 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6781827 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Protein ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_050482214.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_050493138.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050473214.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050489998.1 3 Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331 "Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine" XP_050483386.1 20 MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7338 "6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)" XP_050473024.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050469914.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_050479149.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_050485317.1 6 KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism" XP_050476140.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050470288.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_050474660.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050493224.1 10 KEGG: 05165+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357905;Reactome: R-HSA-5357956;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"T cell receptor signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Human immunodeficiency virus 1 infection" XP_050491135.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050474876.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050485325.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7724 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_050494161.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_050495458.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_050481178.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050471685.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052 "Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state" XP_050491629.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050491839.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_050488532.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_050474344.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-72203 "mRNA Splicing - Major Pathway";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA" XP_050477605.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719 "Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF activation";"Ion transport by P-type ATPases";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors" XP_050486766.1 8 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Recycling pathway of L1";"PI3K-Akt signaling pathway" XP_050478377.1 8 Reactome: R-HSA-6787639;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740;MetaCyc: PWY-66;MetaCyc: PWY-5739;KEGG: 00520+4.2.1.47;MetaCyc: PWY-7573;MetaCyc: PWY-5738 "GDP-fucose biosynthesis";"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-mycosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis" XP_050487417.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_050470442.1 57 Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin" XP_050480805.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050491467.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" XP_050485508.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_050489277.1 7 Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1268020 "Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"ATP biosynthesis";"Mitochondrial protein import" XP_050492080.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050495565.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_050493389.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_050488521.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_050471266.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050497108.1 5 KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-6906;MetaCyc: PWY-5514 "Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_050478516.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA" XP_050484948.1 5 KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22 "Sphingolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_050477561.1 12 Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-982772;Reactome: R-HSA-5362798;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-75893;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Growth hormone receptor signaling";"Release of Hh-Np from the secreting cell";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"TNF signaling";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation" XP_050479119.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_050472961.1 12 MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6121;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6613;KEGG: 00230+6.3.4.13;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9 "5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Aminoacyl-tRNA biosynthesis";"Biotin transport and metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate" XP_050478173.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050492368.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_050475061.1 6 KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788 "Th1 and Th2 cell differentiation";"Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling" XP_050487700.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050472774.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_050469585.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_050484900.1 5 MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;Reactome: R-HSA-73817 "5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" XP_050470169.1 5 MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;Reactome: R-HSA-389661 "Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Proline catabolism";"Glyoxylate metabolism and glycine degradation" XP_050485634.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_050474985.1 2 Reactome: R-HSA-72764;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"Methylation" XP_050494189.1 13 MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;Reactome: R-HSA-499943 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates" XP_050473060.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_050472907.1 4 Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_050479138.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050476914.1 12 Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25 "Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction";"Purine metabolism" XP_050487375.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050473916.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_050491481.1 24 Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-6807878 "Gap junction assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"Kinesins";"Recycling pathway of L1";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"COPI-mediated anterograde transport" XP_050472808.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050477106.1 5 Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging" XP_050472463.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_050493513.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_050492104.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050476167.1 13 MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7254 "Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)" XP_050480781.1 6 Reactome: R-HSA-8951664;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8936459 "Neddylation";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050479531.1 33 Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142 "NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins" XP_050480435.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050488648.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050480808.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050480118.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_050471006.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_050493745.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_050475464.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_050477230.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159 "Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling" XP_050477928.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050478989.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_050493429.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_050481437.1 15 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)" XP_050490728.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_050485400.1 17 KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;MetaCyc: PWY-5789;Reactome: R-HSA-163765;Reactome: R-HSA-200425;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2 "Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism" XP_050484243.1 7 Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798 "Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell" XP_050493087.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_050491922.1 19 Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-8876725;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-3214858;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Translation initiation complex formation";"Protein methylation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"RMTs methylate histone arginines";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_050479157.1 5 Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3 "Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Cysteine and methionine metabolism" XP_050493611.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_050493353.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_050472259.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_050479486.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_050470925.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050475248.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69656 "G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry" XP_050486536.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_050493462.1 8 Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_050472776.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_050471752.1 29 Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167161 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"HIV Transcription Initiation" XP_050493458.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_050480759.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_050484252.1 7 Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684 "HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state" XP_050489188.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_050472298.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444 "COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050481425.1 15 Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence" XP_050483429.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_050475581.1 7 Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1 "Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism" XP_050476387.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_050473927.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_050487168.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" XP_050493231.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_050479233.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_050480129.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050494327.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_050479388.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_050483428.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_050474534.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050489069.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050478806.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050485680.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy" XP_050479800.1 13 Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-139853 "Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Ca2+ pathway";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels" XP_050478131.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050486678.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050477459.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050493098.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_050493694.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050471408.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_050469432.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050470173.1 3 Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793 "RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis" XP_050486392.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050491634.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_050483521.1 11 Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-202733;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253 "Syndecan interactions";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Cell surface interactions at the vascular wall";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_050493165.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_050481109.1 6 KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66 "Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system" XP_050490978.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_050482750.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_050482757.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" XP_050470327.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050473235.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_050484293.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050481215.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050487039.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_050489055.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_050484672.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_050481657.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_050494383.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_050474024.1 9 MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;MetaCyc: PWY-5981 "Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III" XP_050471044.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_050470977.1 13 Reactome: R-HSA-110320;Reactome: R-HSA-5362768;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-3371511;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-8876725;Reactome: R-HSA-5678895;Reactome: R-HSA-8866654;Reactome: R-HSA-382556;Reactome: R-HSA-5689896 "Translesion Synthesis by POLH";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"Josephin domain DUBs";"HSF1 activation";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Protein methylation";"Defective CFTR causes cystic fibrosis";"E3 ubiquitin ligases ubiquitinate target proteins";"ABC-family proteins mediated transport";"Ovarian tumor domain proteases" XP_050488397.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050489322.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-212676 "Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle" XP_050486638.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050488939.1 12 Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-749476 "RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation" XP_050487760.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_050496363.1 9 Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1989781 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock";"PPARA activates gene expression" XP_050473105.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050480817.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050477662.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_050487309.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_050480484.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_050494080.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050486980.1 13 Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-5030;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-6613;KEGG: 00720+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;KEGG: 00670+6.3.4.3 "Metabolism of folate and pterines";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Folate transformations II (plants)";"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate" XP_050493604.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807;Reactome: R-HSA-8854691 "T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling" XP_050495131.1 4 MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494 "Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV" XP_050485298.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050484200.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_050484175.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050479488.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_050478494.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050480314.1 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_050474347.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026 "Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_050470054.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050478462.1 4 KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-5661270 "Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycerol degradation I";"Formation of xylulose-5-phosphate" XP_050486587.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_050481562.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_050486554.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_050486681.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050492137.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events" XP_050476149.1 7 Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-1221632;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813 "Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Meiotic synapsis";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_050486404.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2 "Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism" XP_050482739.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_050473159.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_050472028.1 9 Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920;Reactome: R-HSA-193648 "GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability";"NRAGE signals death through JNK" XP_050470170.1 5 Reactome: R-HSA-70688;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853 "Proline catabolism";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)" XP_050486797.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050495916.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_050486828.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_050471434.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_050481333.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050481410.1 8 Reactome: R-HSA-5083633;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis" XP_050475640.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050473723.1 5 MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation" XP_050490568.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_050496985.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_050492275.1 4 Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277 "Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex" XP_050486248.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050487041.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_050482209.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_050475031.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_050488955.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_050472377.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050481226.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050483011.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050490010.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_050496625.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_050492537.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050494089.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050475037.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050470172.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050473237.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_050490036.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" XP_050483510.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050470414.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_050482300.1 8 Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Activation of RAC1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_050476110.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050486196.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_050485118.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_050472143.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050474781.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050476885.1 29 KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-5693616;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-349425;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-6803207;Reactome: R-HSA-5693568;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-6803204;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804760 "Relaxin signaling pathway";"Processing of DNA double-strand break ends";"Regulation of TP53 Degradation";"Thermogenesis";"Stabilization of p53";"Presynaptic phase of homologous DNA pairing and strand exchange";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Autodegradation of the E3 ubiquitin ligase COP1";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Human papillomavirus infection";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human cytomegalovirus infection";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Methylation" XP_050474515.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050479147.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050479234.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_050488661.1 4 MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)" XP_050484129.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050477926.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_050482210.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_050488714.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050474772.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_050491263.1 3 Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis" XP_050474890.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_050472230.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_050493381.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_050488219.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" XP_050482378.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_050487082.1 9 Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568 "HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_050474854.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050478109.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" XP_050479162.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050473942.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_050489893.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_050470758.1 17 Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-174048 "APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_050488338.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_050472959.1 12 MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.2;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.9 "5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Aminoacyl-tRNA biosynthesis";"Biotin transport and metabolism";"One carbon pool by folate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"One carbon pool by folate" XP_050473974.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050485234.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050477567.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_050474835.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050477904.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_050479267.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_050470767.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_050471790.1 14 KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-3781;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7279;Reactome: R-HSA-611105;MetaCyc: PWY-6728 "Butanoate metabolism";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"Methylaspartate cycle" XP_050483038.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_050481165.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050475915.1 6 Reactome: R-HSA-73930;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-110357 "Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1" XP_050483926.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_050493770.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050488925.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Translation initiation complex formation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" XP_050472795.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050482822.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050489514.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050491985.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050488394.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050491460.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_050492728.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050474168.1 7 KEGG: 00400+1.14.16.1;Reactome: R-HSA-2160456;MetaCyc: PWY-7158;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;MetaCyc: PWY-6134 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylketonuria";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine metabolism";"L-tyrosine biosynthesis IV" XP_050490278.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050493235.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_050486675.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050483701.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_050479357.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_050482278.1 3 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805 "Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation" XP_050489698.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050480653.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_050470056.1 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_050493548.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_050492876.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_050475660.1 11 MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-5659;MetaCyc: PWY-882;Reactome: R-HSA-446205;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;MetaCyc: PWY-7586;MetaCyc: PWY-6992 "Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Mannitol degradation II";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation" XP_050486195.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_050469495.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_050472238.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_050486852.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050487611.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050481201.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_050472702.1 14 Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942 "Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Polymerase switching";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)" XP_050481186.1 3 Reactome: R-HSA-913709;Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117 "O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis" XP_050488321.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050482810.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050473215.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_050477640.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_050470045.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050477610.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050472008.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050490894.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_050483790.1 10 MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8055;Reactome: R-HSA-1483166 "Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA" XP_050469464.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050492592.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050491915.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_050470323.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050493672.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050473116.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689896 "Ub-specific processing proteases";"Ovarian tumor domain proteases" XP_050484453.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050474635.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_050476845.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_050487639.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050476924.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_050474212.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_050490972.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_050479094.1 7 MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_050469893.1 4 Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594 "TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events" XP_050487543.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_050483970.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_050493368.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050476739.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_050476383.1 14 Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity" XP_050487726.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050488829.1 7 Reactome: R-HSA-1474151;MetaCyc: PWY-6614;Reactome: R-HSA-69205;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757;MetaCyc: PWY-3841 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"Folate biosynthesis";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations II (plants)" XP_050484628.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050485049.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_050475644.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050492776.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050482014.1 6 MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5663 "Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I" XP_050485929.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050492536.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050471518.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_050486609.1 12 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167246 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript" XP_050470711.1 12 MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118 "Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Lupulone and humulone biosynthesis";"Methane metabolism";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Chitin degradation to ethanol" XP_050497080.1 4 Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-446199 "Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate" XP_050496210.1 5 Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling" XP_050474606.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_050469529.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050487716.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050491739.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050485731.1 3 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA" XP_050476510.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050471699.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-5826 "Glutathione metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis" XP_050490823.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_050483319.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955 "Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_050485157.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050491736.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_050479137.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050478736.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_050483987.1 5 Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681 "Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT" XP_050471611.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796 "mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation" XP_050492793.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" XP_050494768.1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" XP_050490015.1 15 Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-176034 "Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins" XP_050491470.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_050479247.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_050494056.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_050490249.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050469565.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050479638.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_050475465.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_050483072.1 8 KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1 "Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis" XP_050489272.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_050478107.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" XP_050476381.1 5 KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2 "Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)" XP_050483922.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050490567.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_050472653.1 7 MetaCyc: PWY-6855;KEGG: 00030+3.1.1.31;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-8004;MetaCyc: PWY-5514;Reactome: R-HSA-71336 "Chitin degradation I (archaea)";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway" XP_050473725.1 2 KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_050489152.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_050479121.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_050483782.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-6453 "Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis" XP_050489477.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050493615.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_050484898.1 5 Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6122 "Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II" XP_050470554.1 4 KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030 "Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis" XP_050479983.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050483818.1 11 Reactome: R-HSA-2029485;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8053 "Role of phospholipids in phagocytosis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Sphingolipid metabolism";"Ether lipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II" XP_050489866.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_050496799.1 8 KEGG: 05165+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_050478257.1 8 KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1 "Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism" XP_050480628.1 4 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300 "DNA methylation";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA" XP_050478891.1 8 MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate" XP_050471248.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis" XP_050482768.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_050487001.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_050480243.1 10 Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554 "Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)" XP_050472470.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_050482561.1 11 Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973 "Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation" XP_050487013.1 12 KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053 "Arachidonic acid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II" XP_050481498.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_050482162.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050470168.1 5 KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;Reactome: R-HSA-70688 "Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Proline catabolism" XP_050479996.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_050474893.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_050490227.1 52 Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76066;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-73980;Reactome: R-HSA-8851708;Reactome: R-HSA-167162;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-5601884;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-749476;Reactome: R-HSA-6781823 "NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Termination";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"PIWI-interacting RNA (piRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex" XP_050473936.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_050485877.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_050485393.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050473584.1 5 MetaCyc: PWY-5188;Reactome: R-HSA-189451;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24 "Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism" XP_050478543.1 6 Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_050496407.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_050471676.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050493602.1 3 Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2 "Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway" XP_050470372.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050475802.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050496896.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_050493505.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_050490056.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050479297.1 26 Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-9619483 "Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs" XP_050487218.1 11 Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-193692 "NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR" XP_050469947.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_050475201.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_050491597.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_050489386.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_050485408.1 17 Reactome: R-HSA-163765;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744 "ChREBP activates metabolic gene expression";"Carnitine metabolism";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Glyoxylate assimilation" XP_050479256.1 8 Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport" XP_050473807.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050475568.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_050497097.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_050476245.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_050493095.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_050491064.1 18 KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4 "Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Synthesis of PA";"Anandamide biosynthesis I";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism" XP_050472249.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050470804.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050477695.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_050484503.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_050478549.1 6 MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_050495189.1 4 KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)" XP_050472353.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050477467.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_050477483.1 5 Reactome: R-HSA-4755579;MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94 "Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Androgen biosynthesis";"N-Glycan biosynthesis" XP_050470517.1 4 Reactome: R-HSA-975144;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;MetaCyc: PWY-7511 "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Protein ubiquitination" XP_050479762.1 4 Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-8963889 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes" XP_050492109.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_050479899.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050481117.1 6 Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66 "Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism" XP_050492657.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050481899.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050469409.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_050481806.1 6 KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-5609978;MetaCyc: PWY-6527 "Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Stachyose degradation" XP_050473873.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_050492964.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050483097.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050470526.1 4 KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931 "Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Serotonin and melatonin biosynthesis" XP_050486046.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_050473949.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050477118.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_050483180.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050481478.1 16 Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391 "Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"G alpha (q) signalling events";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling" XP_050480081.1 9 MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664 "Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II" XP_050479832.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050475054.1 4 Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_050480100.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_050485694.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444 "Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050475164.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050487783.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050496490.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_050483157.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050472006.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050492910.1 4 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin" XP_050486965.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_050474552.1 4 Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-428540 "VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Nephrin family interactions";"Activation of RAC1" XP_050470284.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050480317.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050493137.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050471419.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_050473738.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_050489699.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_050473037.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050479993.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_050484983.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050470408.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_050473976.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050496070.1 6 KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695 "Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Peroxisomal protein import";"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation" XP_050476253.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050482275.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050475133.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050492551.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_050488171.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_050480943.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_050484323.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_050484405.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_050477879.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_050485302.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050496387.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050470722.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050480944.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_050488719.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050482146.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism" XP_050490443.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050472800.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050487077.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_050483930.1 16 Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-176407 "Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_050484396.1 12 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_050494162.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_050474056.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_050487764.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050473335.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050472122.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050485799.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_050493778.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_050476357.1 5 Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3 "Pyrimidine salvage";"Pyrimidine catabolism";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes" XP_050488160.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_050484152.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050492770.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050493645.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050477061.1 3 MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367 "3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" XP_050474649.1 3 Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050480286.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_050469648.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050486376.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_050494007.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_050477355.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172 "RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome" XP_050494380.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_050493469.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_050473585.1 12 Reactome: R-HSA-381183;MetaCyc: PWY-5189;Reactome: R-HSA-114608;MetaCyc: PWY-5188;Reactome: R-HSA-381042;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;KEGG: 00860+4.2.1.24;Reactome: R-HSA-381033;Reactome: R-HSA-6798695;Reactome: R-HSA-189451;Reactome: R-HSA-381070 "ATF6 (ATF6-alpha) activates chaperone genes";"Tetrapyrrole biosynthesis II (from glycine)";"Platelet degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Porphyrin and chlorophyll metabolism";"ATF6 (ATF6-alpha) activates chaperones";"Neutrophil degranulation";"Heme biosynthesis";"IRE1alpha activates chaperones" XP_050479926.1 7 Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724 "Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription" XP_050493390.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_050492629.1 6 Reactome: R-HSA-5632684;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-201722 "Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex" XP_050480831.1 29 Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167161 "Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"HIV Transcription Initiation" XP_050471043.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_050478378.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_050494706.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_050496184.1 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" XP_050492334.1 5 Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695 "STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Neutrophil degranulation" XP_050488970.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050489410.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050473311.1 15 Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167290 "TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation" XP_050480830.1 29 Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex" XP_050492140.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_050491127.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050486047.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_050471838.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_050476375.1 5 MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation" XP_050482608.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050470676.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050484472.1 6 MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism" XP_050494492.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_050491692.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050489472.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050493695.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050496142.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050481183.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_050492950.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_050481977.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_050496135.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_050483326.1 9 Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948 "Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants" XP_050480285.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_050483580.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050490123.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050488068.1 52 Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-674695;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-73980;Reactome: R-HSA-8851708;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-5601884;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-6782210;Reactome: R-HSA-72165 "Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Termination";"Signaling by FGFR2 IIIa TM";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway" XP_050492523.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050470313.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_050479669.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_050489112.1 6 MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_050484932.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762 "Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation" XP_050480502.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_050471042.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_050493026.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050487623.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050483806.1 10 Reactome: R-HSA-3000171;Reactome: R-HSA-2453902;MetaCyc: PWY-7394;MetaCyc: PWY-5691;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;Reactome: R-HSA-977225;Reactome: R-HSA-2453864 "Non-integrin membrane-ECM interactions";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Retinoid metabolism and transport";"Neutrophil degranulation";"Purine metabolism";"Urate conversion to allantoin III";"Amyloid fiber formation";"Retinoid cycle disease events" XP_050485737.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050494376.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_050480630.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_050479674.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_050474178.1 3 Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741 "Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_050489627.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_050491601.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_050473482.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050486339.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_050482231.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_050489151.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_050492580.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_050496133.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_050486713.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_050478110.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_050496952.1 4 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_050471691.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050494764.1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" XP_050480075.1 4 MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_050477385.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_050473850.1 13 KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883 "Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II" XP_050470043.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050491702.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_050470567.1 7 Reactome: R-HSA-1655829;Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5578749 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs" XP_050489534.1 17 Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-176187;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1221632;KEGG: 05163+2.7.11.1 "Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Human papillomavirus infection";"Activation of ATR in response to replication stress";"Human immunodeficiency virus 1 infection";"Meiotic synapsis";"Human cytomegalovirus infection" XP_050496408.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_050471304.1 8 Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050481307.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050487391.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_050494216.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1" XP_050487156.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_050476165.1 13 KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7254;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2 "Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes" XP_050489276.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_050473378.1 12 Reactome: R-HSA-5655302;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1 "Signaling by FGFR1 in disease";"Human immunodeficiency virus 1 infection";"Signaling by cytosolic FGFR1 fusion mutants";"Human cytomegalovirus infection";"Rho GTPase cycle";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"NRAGE signals death through JNK";"Human papillomavirus infection" XP_050480127.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_050492021.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_050477481.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_050482815.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050487269.1 7 Reactome: R-HSA-71403;MetaCyc: PWY-5084;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71064 "Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism" XP_050470285.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050475249.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69656 "G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry" XP_050480884.1 12 KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476 "Human papillomavirus infection";"NRAGE signals death through JNK";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Rho GTPase cycle";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events" XP_050494016.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_050492480.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_050482013.1 6 MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6983 "Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis" XP_050482274.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050478567.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_050474889.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_050480860.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_050476466.1 10 Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.159;Reactome: R-HSA-983231;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6554;MetaCyc: PWY-6366;Reactome: R-HSA-1855204;MetaCyc: PWY-6362;MetaCyc: PWY-6365 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis" XP_050483329.1 9 Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946 "Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants" XP_050487023.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725 "Fatty acid elongation";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_050485548.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050485930.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_050472574.1 7 MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277 "5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_050485334.1 14 MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725 "Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_050476890.1 6 KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_050490563.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_050476901.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_050494060.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_050492231.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516 "Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin" XP_050475845.1 5 KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;MetaCyc: PWY-8060;Reactome: R-HSA-71336;Reactome: R-HSA-6798695 "Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"Neutrophil degranulation" XP_050487562.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_050489031.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050480924.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050491829.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050492771.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050495043.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_050469917.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_050475060.1 6 Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16 "Circadian Clock";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050486547.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_050483729.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050471610.1 5 Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24 "FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway" XP_050472984.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050489903.1 4 KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801 "Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion" XP_050485935.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_050486245.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050472709.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_050493245.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214 "DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_050483717.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_050494735.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409 "Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis" XP_050483221.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050491136.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050470337.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050470661.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050480498.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_050489520.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_050486337.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_050473377.1 12 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-5655302;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"NRAGE signals death through JNK";"Human papillomavirus infection";"Rho GTPase cycle";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease";"Human immunodeficiency virus 1 infection" XP_050477603.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-111932 "Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Long-term potentiation";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB" XP_050473971.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050482097.1 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" XP_050488190.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-4086400;Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4641262 "RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"PCP/CE pathway";"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_050473620.1 56 Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-174084 "Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_050486814.1 7 Reactome: R-HSA-73817;MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-7221;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205 "Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Purine metabolism" XP_050484865.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones" XP_050492253.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_050491682.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_050474091.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050493328.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_050480927.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050479555.1 9 Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends" XP_050493102.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_050492331.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_050471094.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050471364.1 4 Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356 "TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_050475954.1 11 Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210 "Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_050482919.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050471259.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_050474901.1 9 MetaCyc: PWY-6351;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Phosphatidylinositol signaling system" XP_050483315.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952 "Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions" XP_050481555.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050494015.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_050471985.1 14 MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-561;MetaCyc: PWY-4302;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-3781;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1 "Methylaspartate cycle";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism" XP_050482006.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_050472187.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_050477795.1 12 Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6804756 "Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation" XP_050493085.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_050477777.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins" XP_050491079.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" XP_050478847.1 6 KEGG: 00750+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;KEGG: 00270+2.6.1.52 "Vitamin B6 metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism" XP_050488815.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_050492832.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050473676.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050494247.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050482548.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050472556.1 3 Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" XP_050474736.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_050489079.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_050470720.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_050482759.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050487641.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050477452.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-5689877 "DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Josephin domain DUBs" XP_050493468.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_050487621.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_050470247.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050487252.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-977225 "TBC/RABGAPs";"Amyloid fiber formation" XP_050488716.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050483047.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases" XP_050493700.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_050469465.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050470243.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050485633.1 5 MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6 "D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_050474224.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_050481923.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_050494335.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050483227.1 3 KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686 "Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I" XP_050488169.1 10 Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-9022538 "NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA" XP_050482730.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050475042.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050496812.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_050489043.1 4 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_050471309.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_050473581.1 7 Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-381042;Reactome: R-HSA-381183 "ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes" XP_050473328.1 14 MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-8053 "Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II" XP_050477117.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_050493518.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_050495567.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols" XP_050475673.1 14 MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602 "Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_050476188.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_050481618.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_050494188.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_050487470.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050484921.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050490655.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050488887.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050489928.1 19 Reactome: R-HSA-6798695;Reactome: R-HSA-75105;MetaCyc: PWY-5913;MetaCyc: PWY-5537;KEGG: 00020+2.3.3.8;Reactome: R-HSA-163765;MetaCyc: PWY-5172;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5 "Neutrophil degranulation";"Fatty acyl-CoA biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Propanoate metabolism" XP_050478980.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_050481717.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_050480289.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050479484.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_050470276.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050491680.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_050478752.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane" XP_050488168.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050489489.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_050493543.1 14 MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634 "Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport" XP_050482164.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050470569.1 7 Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-180746 "Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein" XP_050478385.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_050494238.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_050472089.1 4 Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis" XP_050481933.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_050477108.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-1368108 "Neutrophil degranulation";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_050492571.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint" XP_050474745.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_050476700.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050494953.1 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" XP_050479380.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_050480806.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050477294.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_050485992.1 3 Reactome: R-HSA-5689880;Reactome: R-HSA-110314;Reactome: R-HSA-6783310 "Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway" XP_050469391.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050473802.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050491458.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_050480715.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050470525.1 7 KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-7838;MetaCyc: PWY-5129;MetaCyc: PWY-7836;MetaCyc: PWY-7841 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis" XP_050472658.1 17 Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565 "Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_050474837.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050473436.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol" XP_050485495.1 8 Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;MetaCyc: PWY-7221 "Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis" XP_050490973.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_050491785.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050487688.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_050478496.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050475182.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_050469649.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050472088.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938 "Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)" XP_050493020.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_050488944.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050481163.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050482338.1 7 Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;MetaCyc: PWY-7221;Reactome: R-HSA-73817;MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596 "Neutrophil degranulation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I" XP_050492388.1 4 Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852 "Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Macroautophagy" XP_050490746.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_050481302.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_050470664.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050486637.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050488210.1 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_050483474.1 18 KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00960+2.6.1.1;MetaCyc: PWY-5913 "Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"(R)-cysteate degradation";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"Sulfolactate degradation III";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)" XP_050497029.1 14 MetaCyc: PWY-5076;Reactome: R-HSA-70895;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5104;MetaCyc: PWY-5057;MetaCyc: PWY-7767 "L-leucine degradation III";"Branched-chain amino acid catabolism";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis IV";"L-valine degradation II";"L-leucine degradation IV (Stickland reaction)" XP_050487991.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050482280.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050486691.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_050483849.1 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" XP_050493257.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050470915.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_050482485.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_050487323.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_050488107.1 3 Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" XP_050491896.1 24 Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-416482 "ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Ca2+ pathway";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events" XP_050488641.1 4 Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862 "Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK" XP_050489450.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_050475085.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050482952.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050480948.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050473965.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050472002.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050478203.1 11 Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-170670 "G alpha (s) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway" XP_050482282.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050490931.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_050486532.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_050481234.1 33 Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-141444 "Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050487972.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_050478376.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_050475378.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_050478293.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_050495183.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050479276.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_050472254.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_050496915.1 3 Reactome: R-HSA-420029;Reactome: R-HSA-4608870;Reactome: R-HSA-2173791 "Tight junction interactions";"Asymmetric localization of PCP proteins";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)" XP_050490128.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050489929.1 19 Reactome: R-HSA-6798695;MetaCyc: PWY-5913;Reactome: R-HSA-75105;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5537;MetaCyc: PWY-5172;Reactome: R-HSA-163765;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5 "Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Propanoate metabolism";"C5-Branched dibasic acid metabolism" XP_050488422.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_050469847.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050472708.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_050480936.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_050478553.1 5 Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825 "Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis" XP_050484468.1 6 KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6364 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis" XP_050491639.1 7 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14 "Purine metabolism";"Thiamine metabolism";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes" XP_050481491.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_050494054.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_050482632.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_050485064.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050476967.1 14 MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4 "Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Arachidonic acid metabolism" XP_050480102.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_050475013.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_050471438.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_050483568.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050492490.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_050490089.1 4 Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26 "A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate" XP_050493773.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_050472374.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050484940.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_050484429.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane" XP_050481534.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050478545.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_050469976.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442 "ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs" XP_050489017.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050484125.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_050487578.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"O-linked glycosylation" XP_050490569.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_050470248.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050477220.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050475555.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_050493710.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_050481235.1 10 KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11 "Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_050482225.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis" XP_050485687.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_050481343.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_050492968.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050489658.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" XP_050472210.1 5 Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787 "Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog 'off' state" XP_050470859.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_050476784.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050472888.1 6 KEGG: 00520+5.4.2.10;Reactome: R-HSA-446210;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6749;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation" XP_050480949.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_050496925.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050477272.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_050472005.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050469706.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_050481801.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_050476585.1 10 MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861 "Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Galactose metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_050482281.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050474095.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050469624.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050493786.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050488943.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050477717.1 12 Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_050482787.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_050484510.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_050488189.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262 "RHO GTPases Activate Formins";"Degradation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_050496909.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_050486052.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050483935.1 5 MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954;MetaCyc: PWY-7919;Reactome: R-HSA-532668 "Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_050477925.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050488844.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_050472251.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050489014.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050487644.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050489291.1 20 Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-5693607 "Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Processing of DNA double-strand break ends" XP_050480841.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-212436 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway" XP_050470663.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050482294.1 2 MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_050472521.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878 "COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport" XP_050478044.1 8 Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483 "Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs" XP_050470828.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050474314.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_050477286.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Purine metabolism";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" XP_050470071.1 3 KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1 "Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway" XP_050471954.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050481600.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion" XP_050477038.1 7 MetaCyc: PWY-6840;Reactome: R-HSA-174403;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2 "Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism" XP_050481170.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050494087.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050474219.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-3238698 "Neutrophil degranulation";"WNT ligand biogenesis and trafficking" XP_050496360.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472 "PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_050483432.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_050476582.1 10 MetaCyc: PWY-7385;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11 "1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Methane metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis" XP_050489293.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_050478708.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)" XP_050477619.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802955 "Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_050469563.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_050475084.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_050492946.1 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes" XP_050477923.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_050471683.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867 "Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex" XP_050492757.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_050486624.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_050475306.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_050475504.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_050483314.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952 "Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions" XP_050471525.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_050491008.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050492363.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_050480925.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050475538.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_050482027.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050492588.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050477779.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_050477994.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_050484697.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_050494088.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050482736.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_050469902.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050481798.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_050489474.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050473310.1 15 Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-167158 "Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex" XP_050481656.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_050477037.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050472471.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_050476228.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_050495835.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876 "Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs" XP_050477134.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_050496837.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050469943.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_050480945.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050482475.1 6 Reactome: R-HSA-5632968;Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648 "Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes" XP_050475528.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_050471081.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_050492462.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050474526.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_050479080.1 3 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism" XP_050491648.1 7 MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism" XP_050469458.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050474007.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_050486384.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_050478476.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050470689.1 33 Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408 "NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism" XP_050476798.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_050483860.1 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" XP_050485331.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)" XP_050493001.1 12 KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932 "Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction" XP_050481905.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_050474554.1 4 Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-4420097 "Activation of RAC1";"Nephrin family interactions";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway" XP_050477781.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins" XP_050469924.1 3 Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760 "RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation" XP_050470951.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_050481653.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_050473622.1 3 Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17 "Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis" XP_050489807.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20 "Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism" XP_050494051.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_050488670.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050478550.1 6 KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_050487442.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_050488824.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050494206.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes" XP_050475044.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_050474016.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_050480527.1 3 Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320 "Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH" XP_050485281.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_050489619.1 7 KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7791 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"UMP biosynthesis III" XP_050474805.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_050470301.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_050490820.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_050484680.1 6 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_050472520.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_050495346.1 11 Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631 "Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility" XP_050476636.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050478822.1 14 KEGG: 04070+3.1.4.11;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-1855204;Reactome: R-HSA-434316;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-399997;Reactome: R-HSA-112043;MetaCyc: PWY-6367;Reactome: R-HSA-418217;MetaCyc: PWY-6351 "Phosphatidylinositol signaling system";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"Synthesis of IP3 and IP4 in the cytosol";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Acetylcholine regulates insulin secretion";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"G beta:gamma signalling through PLC beta";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_050486466.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375280 "G alpha (q) signalling events";"Amine ligand-binding receptors" XP_050471608.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580 "mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence" XP_050484766.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050480814.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050482968.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050492712.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_050491959.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050470317.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050479942.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050491986.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_050469746.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_050483012.1 5 MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_050474916.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050482010.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-1433559 "Neddylation";"Regulation of KIT signaling" XP_050489741.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_050474747.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_050486960.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050474030.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_050479853.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050472742.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_050487763.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_050487599.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050484625.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050485014.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_050480123.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_050471172.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_050486607.1 12 Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152 "RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat" XP_050489012.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050480758.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050479605.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050477287.1 11 Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-170670 "Hedgehog 'off' state";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway" XP_050473107.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050488602.1 4 KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;MetaCyc: PWY-7250;Reactome: R-HSA-947581 "Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis" XP_050473926.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_050475171.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050469952.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_050484980.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050472137.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1" XP_050473940.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_050477174.1 5 Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-9627069 "SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity" XP_050479886.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050471510.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_050476562.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_050487233.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050470907.1 13 MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7410;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-7659;MetaCyc: PWY-7736 "(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis" XP_050474012.1 5 Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050490653.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050478607.1 4 Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922 "Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_050489908.1 4 KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603 "Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine" XP_050481607.1 8 Reactome: R-HSA-5689880;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "Ub-specific processing proteases";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_050475039.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050478809.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050470912.1 5 KEGG: 00230+3.6.1.6;MetaCyc: PWY-7210;MetaCyc: PWY-7185;Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6 "Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Neutrophil degranulation";"Pyrimidine metabolism" XP_050478285.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050477655.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_050487689.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" XP_050483805.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050477927.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050490817.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_050477137.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_050496395.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-6804115;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_050491710.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_050489340.1 13 Reactome: R-HSA-437239;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-8866427;Reactome: R-HSA-416993 "Recycling pathway of L1";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"LDL clearance";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors" XP_050477929.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050483441.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050477591.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324 "Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_050479139.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050490607.1 5 Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994 "Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_050469919.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_050480733.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_050472114.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050492716.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050475192.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_050476916.1 12 KEGG: 00230+2.7.1.25;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550 "Purine metabolism";"Selenate reduction";"Selenocompound metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Purine metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se" XP_050481622.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_050477086.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_050477115.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050490152.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_050483494.1 13 KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7198 "Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_050483113.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050489033.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050488717.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050476216.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050485615.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601 "Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_050497024.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_050473966.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050483549.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_050488271.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_050485744.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050480108.1 5 MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891 "Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)" XP_050489295.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_050482301.1 3 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_050489774.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_050473490.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_050483808.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050476102.1 16 MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-2046105;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6433;Reactome: R-HSA-2046106;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199 "Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Linoleic acid (LA) metabolism";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"alpha-linolenic acid (ALA) metabolism";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Fatty acid elongation" XP_050483085.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050493605.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_050486631.1 17 Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-5689880;Reactome: R-HSA-450302;Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956;Reactome: R-HSA-4086398;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-202424;Reactome: R-HSA-937042;Reactome: R-HSA-9020702;Reactome: R-HSA-937072;Reactome: R-HSA-2871837 "CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"Ub-specific processing proteases";"activated TAK1 mediates p38 MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway";"Ca2+ pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex";"Interleukin-1 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FCERI mediated NF-kB activation" XP_050474288.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_050473724.1 11 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_050481517.1 4 Reactome: R-HSA-901032;KEGG: 00513+3.2.1.113;KEGG: 00510+3.2.1.113;MetaCyc: PWY-7919 "ER Quality Control Compartment (ERQC)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)" XP_050484463.1 7 Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67 "Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism" XP_050480730.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_050491231.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214 "Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_050473238.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_050491307.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050489488.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_050473952.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_050489321.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676 "Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle" XP_050492718.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050471513.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050492582.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050470058.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_050477229.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5628897 "Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling";"TP53 Regulates Metabolic Genes" XP_050494767.1 2 Reactome: R-HSA-5655302;Reactome: R-HSA-1839117 "Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants" XP_050490390.1 6 KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22 "Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions" XP_050486906.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_050481467.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050485706.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation" XP_050496961.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050477142.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-180024 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events" XP_050473054.1 18 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7205;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_050478756.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_050472048.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050487602.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_050491542.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_050477739.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050482161.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050493127.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050482208.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_050488329.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050472193.1 12 Reactome: R-HSA-71240;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;MetaCyc: PWY-6309;MetaCyc: PWY-2821;MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13 "Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism" XP_050487189.1 34 Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-9639288;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180746 "Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amino acids regulate mTORC1";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Nuclear import of Rev protein" XP_050478734.1 2 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_050480500.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_050476834.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA" XP_050497037.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050489892.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_050481958.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_050470239.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050491732.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050477616.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-111932 "Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB" XP_050487334.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_050494179.1 13 MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_050478805.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050480912.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050480960.1 6 MetaCyc: PWY-5497;MetaCyc: PWY-7442;MetaCyc: PWY-6608;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606 "Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation II" XP_050476713.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_050481450.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" XP_050477588.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9620244 "Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Long-term potentiation" XP_050487642.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050488523.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_050473163.1 9 Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-6794361 "EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Neurexins and neuroligins" XP_050490221.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050486314.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_050496801.1 11 Reactome: R-HSA-5668599;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-109704;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "RHO GTPases Activate NADPH Oxidases";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Inositol phosphate metabolism";"Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_050472547.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_050472104.1 58 Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-5689901;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176 "Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"MAPK6/MAPK4 signaling";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Metalloprotease DUBs";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_050470752.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050470281.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050492847.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_050493942.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_050484508.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_050495647.1 10 Reactome: R-HSA-2894862;Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_050492010.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050487520.1 6 Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-9022537 "HDACs deacetylate histones";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex" XP_050482740.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_050485481.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050484398.1 12 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_050475886.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050493457.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050486030.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_050483321.1 9 Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948 "Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants" XP_050481901.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane" XP_050478589.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050480328.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes" XP_050485824.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_050490409.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050492319.1 12 MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801 "Sucrose biosynthesis II";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Stachyose degradation";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)" XP_050473218.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_050494048.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_050491855.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_050491973.1 5 KEGG: 00270+1.1.1.95;KEGG: 00260+1.1.1.95;Reactome: R-HSA-977347;KEGG: 00680+1.1.1.95;MetaCyc: PWY-8010 "Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)" XP_050488724.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050474997.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_050482877.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050477942.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-73779 "HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_050492250.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050493470.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_050471255.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_050485873.1 14 Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-6798695;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-1474228;Reactome: R-HSA-3928665 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Degradation of the extracellular matrix";"EPH-ephrin mediated repulsion of cells" XP_050470236.1 27 Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-3371453 "SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response" XP_050491638.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_050486054.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508 "Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_050488524.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_050494755.1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" XP_050470857.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_050474116.1 9 MetaCyc: PWY-7112;Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18 "4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes" XP_050490296.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_050473677.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050481814.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_050474678.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-3108214 "Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins" XP_050485808.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_050494052.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_050475741.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050473104.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050485299.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050477546.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050478874.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_050488302.1 13 KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7533;Reactome: R-HSA-196836;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842;Reactome: R-HSA-156590 "Drug metabolism - other enzymes";"Glutathione metabolism";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II";"Glutathione conjugation" XP_050475959.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_050492870.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes" XP_050491709.1 4 Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483 "Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)" XP_050471237.1 18 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Viral mRNA Translation" XP_050487456.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis" XP_050497027.1 14 MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5101;MetaCyc: PWY-5057;MetaCyc: PWY-7767;Reactome: R-HSA-70895;MetaCyc: PWY-5076;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42 "L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis II";"L-valine degradation II";"L-leucine degradation IV (Stickland reaction)";"Branched-chain amino acid catabolism";"L-leucine degradation III";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis" XP_050492314.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050470340.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050493801.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_050477315.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_050477029.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_050479966.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_050470558.1 20 Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-69473 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint" XP_050487982.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050494053.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_050476215.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050477604.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-936837 "Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"RAF activation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases" XP_050474422.1 7 KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2 "Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism" XP_050493871.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_050477806.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050482004.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER" XP_050471505.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_050478600.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050485611.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602 "Fatty acid elongation";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_050471258.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_050482341.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050483656.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050489022.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050469856.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_050479224.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_050470598.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050491321.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_050486402.1 3 Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2" XP_050473996.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_050475586.1 4 KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I" XP_050487808.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_050483728.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050474009.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_050476613.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_050474900.1 9 MetaCyc: PWY-6351;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Phosphatidylinositol signaling system" XP_050482174.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050477623.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-111932 "Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Long-term potentiation";"RAF activation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB" XP_050491413.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_050472579.1 7 MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817 "5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_050469410.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_050480834.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_050479911.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_050484202.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_050493103.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_050472814.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_050470619.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_050495840.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_050480739.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_050486278.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_050489516.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_050492575.1 11 Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616 "Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_050483908.1 22 MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5353;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7606;MetaCyc: PWY-6958;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs" XP_050481404.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_050486552.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_050473038.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050481561.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_050469747.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_050469582.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_050474454.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695 "Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling" XP_050482376.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_050485765.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_050472817.1 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_050494219.1 7 MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_050492966.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050473962.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050479106.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_050476055.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050476481.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_050471519.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050487978.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050494194.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_050480241.1 10 KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-4661 "Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_050479116.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_050478861.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion" XP_050470732.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_050471243.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis" XP_050489010.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_050487255.1 29 Reactome: R-HSA-3371453;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-3371511;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-912446 "Regulation of HSF1-mediated heat shock response";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HSF1 activation";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Meiotic recombination" XP_050472102.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050471895.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050496631.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_050471807.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_050475992.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_050484450.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050493629.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050488877.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050491239.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466 "Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis" XP_050494226.1 7 MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050476231.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_050474220.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050484067.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050487750.1 52 Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-73980;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-73780;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-76071 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Termination";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_050479915.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050484981.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050483990.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511 "Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination" XP_050486971.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050489124.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050485477.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050469598.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050488209.1 3 Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887 "tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation" XP_050481722.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050470669.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050485683.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion" XP_050480359.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050474457.1 5 Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243 "Interleukin-7 signaling";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050496794.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050487324.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_050486287.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_050471562.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050482650.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_050480722.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133 "Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1" XP_050487171.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050492326.1 12 MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9 "Sucrose biosynthesis II";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Stachyose degradation";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism" XP_050477612.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952 "Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"RAF activation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions" XP_050470217.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050489283.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_050474897.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050485658.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050477471.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_050474284.1 4 Reactome: R-HSA-446193;Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_050482953.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_050489858.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_050484489.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_050473777.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050491827.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_050487199.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050497052.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_050493118.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050483290.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_050488097.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase" XP_050476917.1 12 KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25 "Monobactam biosynthesis";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Selenate reduction";"Selenocompound metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Purine metabolism" XP_050477652.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_050492700.1 12 MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-6708;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5870 "Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)" XP_050471041.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_050476379.1 5 MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" XP_050482814.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050474346.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-9610379;Reactome: R-HSA-72203;Reactome: R-HSA-4570464 "mRNA Splicing - Major Pathway";"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA";"SUMOylation of RNA binding proteins" XP_050482414.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050486918.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050473992.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_050475158.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050494005.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_050475075.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050473919.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_050471641.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_050493425.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_050479940.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050482284.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_050488218.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_050489468.1 8 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_050488328.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050484534.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050490577.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_050483527.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050484190.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050491577.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_050477036.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_050495038.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409 "Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis" XP_050488213.1 3 MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450 "Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion" XP_050492731.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050484311.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_050484761.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_050470954.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050491984.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050470504.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_050472822.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050488727.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050492442.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_050469567.1 5 MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_050474555.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050472255.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_050483715.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_050478464.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_050469581.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_050491626.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_050484507.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_050489394.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_050482560.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_050473928.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_050477895.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050472803.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050484639.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_050492753.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_050485704.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation" XP_050473678.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050483356.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-6811558 "Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_050484681.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_050494993.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_050482564.1 11 Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-428890 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling" XP_050469670.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_050480290.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050484588.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_050486846.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050480503.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_050477805.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050491259.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211945;Reactome: R-HSA-211981 "Endogenous sterols";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds";"Xenobiotics" XP_050493258.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050479676.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_050478558.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_050488938.1 12 Reactome: R-HSA-1834949;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-73762;Reactome: R-HSA-749476 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation" XP_050485168.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050479470.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_050487826.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_050471996.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050471064.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050477860.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050489187.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_050484404.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_050488355.1 14 Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862 "Translesion synthesis by REV1";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Polymerase switching";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK" XP_050478716.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050489333.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation" XP_050494249.1 11 Reactome: R-HSA-391160;Reactome: R-HSA-432142;Reactome: R-HSA-389948;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-909733;Reactome: R-HSA-877312;Reactome: R-HSA-912694;Reactome: R-HSA-9008059;Reactome: R-HSA-210990 "Signal regulatory protein family interactions";"Platelet sensitization by LDL";"PD-1 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Interferon alpha/beta signaling";"Regulation of IFNG signaling";"Regulation of IFNA signaling";"Interleukin-37 signaling";"PECAM1 interactions" XP_050480438.1 24 KEGG: 04151+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-9634635;Reactome: R-HSA-2730905;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5218921;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Integrin signaling";"Estrogen-stimulated signaling through PRKCZ";"Role of LAT2/NTAL/LAB on calcium mobilization";"Relaxin signaling pathway";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Thermogenesis";"Downstream TCR signaling";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"Activation of AKT2";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"RSK activation";"VEGFR2 mediated cell proliferation";"Human cytomegalovirus infection" XP_050469863.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_050486966.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050483497.1 13 KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_050494449.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516 "Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin" XP_050469470.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_050494293.1 23 Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-418594 "Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G-protein activation";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events" XP_050493398.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_050489458.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159 "Macroautophagy";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling" XP_050496613.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050472850.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050476759.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_050485034.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_050492577.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-69166 "Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate" XP_050489137.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377 "Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of SUMOylation proteins" XP_050485029.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050485518.1 13 Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-419037;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-3000157;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-1442490 "Collagen chain trimerization";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"NCAM1 interactions";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Laminin interactions";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Extracellular matrix organization";"Collagen degradation" XP_050485565.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050487637.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050493665.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050486249.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050491211.1 22 Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358751 "APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Trunc