Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_012243415.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_012249575.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024227331.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024224627.1 3 Reactome: R-HSA-159740;MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90 "Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_012249697.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_003492267.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_024228112.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012239362.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_024224201.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003490075.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_003490785.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_024220298.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012247311.2 9 Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948 "Signaling downstream of RAS mutants";"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants" XP_024227611.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_003487244.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003487895.1 20 Reactome: R-HSA-9639288;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-166208;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;KEGG: 05165+2.7.11.1 "Amino acids regulate mTORC1";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Human cytomegalovirus infection";"Macroautophagy";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"HSF1-dependent transactivation";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Thermogenesis";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"Human papillomavirus infection" XP_024221231.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012239744.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012239040.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_003489635.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003491989.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_024222188.1 5 Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_003485376.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_024223151.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_012240303.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_024221601.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558 "Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K Cascade";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_024226960.1 14 Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-6798695;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-1474228;Reactome: R-HSA-977225 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Neutrophil degranulation";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Degradation of the extracellular matrix";"Amyloid fiber formation" XP_024226766.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_024222614.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_012246798.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024224672.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080 "Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" XP_012237857.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_024226089.1 15 Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-5467333;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-3769402;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Deactivation of the beta-catenin transactivating complex";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated" XP_003485375.1 3 Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490 "Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation" XP_012249649.1 6 Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122 "Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis" XP_012241855.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024222034.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_024226039.1 14 Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167200 "Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_003489037.1 5 Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;MetaCyc: PWY-5381 "Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)" XP_024221086.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_003485638.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012243385.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024227606.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012239356.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670 "Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway" XP_003489725.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_024226396.1 12 MetaCyc: PWY-3801;MetaCyc: PWY-6527;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599 "Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate" XP_012243996.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_024220635.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_024223813.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_012237144.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_012243488.1 57 Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553 "Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs" XP_012236936.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012238167.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_012237536.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_024224076.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012242937.1 8 Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747 "Ub-specific processing proteases";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization" XP_012242202.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012246736.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_024224636.1 6 Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761 "Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)" XP_012240188.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003485852.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_024226664.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_012236479.1 6 MetaCyc: PWY-6906;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;MetaCyc: PWY-5514;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.3 "Chitin derivatives degradation";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism" XP_012248534.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003487878.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_024225304.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_012239330.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_024227325.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003485576.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012242024.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003487883.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024223481.1 11 Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-174430;Reactome: R-HSA-5685942 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"DNA replication initiation";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)" XP_024222855.1 14 KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-975634 "alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Retinoid metabolism and transport" XP_024224647.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012240770.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024226950.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012241282.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024226916.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003485590.1 3 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes" XP_003490931.1 2 Reactome: R-HSA-69231;Reactome: R-HSA-8934593 "Cyclin D associated events in G1";"Regulation of RUNX1 Expression and Activity" XP_012249239.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012237201.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012240738.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003486418.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_024221777.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_003493441.1 7 KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;MetaCyc: PWY-6134;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158 "Folate biosynthesis";"Phenylalanine metabolism";"Phenylketonuria";"Phenylalanine metabolism";"L-tyrosine biosynthesis IV";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V" XP_003489336.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012244291.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_003490634.1 3 Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709 "Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins" XP_012238079.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012246844.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_024225251.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012249146.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012246233.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012246621.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_024223292.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_024221468.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_003489562.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012243822.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_024228045.1 10 Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6372;MetaCyc: PWY-6369;MetaCyc: PWY-6361;MetaCyc: PWY-4661;MetaCyc: PWY-6362 "Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_024225770.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-8866654;Reactome: R-HSA-110314 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex" XP_003494112.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_003487993.1 11 KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-525793;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-8939236 "T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myogenesis";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_024222403.1 7 MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;Reactome: R-HSA-5578999;MetaCyc: PWY-6840;MetaCyc: PWY-7255 "Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)" XP_012248535.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003490127.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_024226897.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012249696.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_012248141.1 12 MetaCyc: PWY-7385;Reactome: R-HSA-70263;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13 "1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Methane metabolism" XP_024224621.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_024226785.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012236314.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024224997.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024221527.1 8 Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1 "Glycolysis";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Galactose metabolism";"Streptomycin biosynthesis" XP_012244727.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_003491387.1 10 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-437239;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"RSK activation";"Recycling pathway of L1";"Relaxin signaling pathway" XP_003488895.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012238911.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447 "RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria" XP_012245669.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_003486398.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012240848.1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-174437;Reactome: R-HSA-5685938 "HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)" XP_024226141.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012238417.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003491361.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003493654.1 3 Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078 "GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)" XP_024222962.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972 "Sciadonate biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)" XP_012237473.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_012244284.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_012250317.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024228149.1 5 KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3 "Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_003493505.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024227883.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends" XP_024227180.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003487887.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_012248624.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_024221284.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024223561.1 33 Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638 "Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins" XP_012246647.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_024220206.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024220746.1 6 Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516 "Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane" XP_024221771.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_012241714.1 4 Reactome: R-HSA-8964011;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463;Reactome: R-HSA-196741 "HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_012239681.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_012245260.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-442982 "Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Long-term potentiation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor" XP_024224548.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003489600.1 5 Reactome: R-HSA-5675221;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948 "Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants" XP_012236968.1 6 MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_024222259.1 5 MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_024227731.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012237221.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_003491546.1 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" XP_003485604.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003485030.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003494087.1 56 Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764 "CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Regulation of RAS by GAPs";"UCH proteinases";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling" XP_012244087.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003491665.1 33 Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-69202;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-69656;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-69273;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-69231;Reactome: R-HSA-5696395 "Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"Cyclin A:Cdk2-associated events at S phase entry";"mRNA Capping";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin D associated events in G1";"Formation of Incision Complex in GG-NER" XP_012236417.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362277 "Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex" XP_012249112.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003487797.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003484744.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012244415.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024225791.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_024223552.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003491864.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_024222988.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_024222558.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_024226927.1 34 Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-9639288;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Amino acids regulate mTORC1";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins" XP_003491510.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_003487351.1 5 Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785 "Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome" XP_012249803.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_024221280.1 4 Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188 "Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)" XP_003488356.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060;MetaCyc: PWY-7180 "Neutrophil degranulation";"Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation" XP_024220607.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_003486694.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_003486213.1 5 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-201722 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex" XP_012236983.1 11 Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756 "AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation" XP_024221528.1 8 KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_012244366.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003486019.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_003489721.1 33 Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408 "Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"HCMV Early Events";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism" XP_024225379.1 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_024227244.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-912631 "MET receptor recycling";"Downstream signal transduction";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL" XP_003494072.1 4 Reactome: R-HSA-6782315;Reactome: R-HSA-156581;Reactome: R-HSA-72764;Reactome: R-HSA-6790901 "tRNA modification in the nucleus and cytosol";"Methylation";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol" XP_003493784.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012241638.1 14 Reactome: R-HSA-168333;Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-5687128;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-2173788;Reactome: R-HSA-9634638;Reactome: R-HSA-141444;Reactome: R-HSA-3769402 "NEP/NS2 Interacts with the Cellular Export Machinery";"HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"MAPK6/MAPK4 signaling";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"Downregulation of TGF-beta receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deactivation of the beta-catenin transactivating complex" XP_024226746.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_024225653.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012239543.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208 "Amino acids regulate mTORC1";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling" XP_012247533.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012236745.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_012242121.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_003491567.1 8 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Activation of RAC1";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_003491576.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_012243295.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_003486828.1 9 Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-9639288 "TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"MAP2K and MAPK activation";"Amino acids regulate mTORC1" XP_012236493.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003488024.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012247407.1 3 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis" XP_003492363.1 3 MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9 "Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_024221674.1 7 Reactome: R-HSA-5693571;Reactome: R-HSA-983168;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565;MetaCyc: PWY-7511;Reactome: R-HSA-69473 "Nonhomologous End-Joining (NHEJ)";"Antigen processing: Ubiquitination & Proteasome degradation";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination";"G2/M DNA damage checkpoint" XP_024222448.1 57 Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-180585 "GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G" XP_012240630.1 29 Reactome: R-HSA-912446;Reactome: R-HSA-5651801;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-3108214;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-3371511;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-68962;Reactome: R-HSA-5693616;Reactome: R-HSA-174437 "Meiotic recombination";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HSF1 activation";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Activation of the pre-replicative complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand" XP_012244918.1 8 MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-922 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway I" XP_012237200.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012247170.1 17 KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-6722;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-6679 "Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Propanoate metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Jadomycin biosynthesis" XP_024222896.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003493974.1 20 Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756 "G2/M DNA damage checkpoint";"Polymerase switching";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation" XP_024222385.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_012246199.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003491130.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_024224604.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012249815.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_024227335.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012247531.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003486688.1 179 Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-1169408;Reactome: R-HSA-5205685;Reactome: R-HSA-201681;Reactome: R-HSA-8951664;Reactome: R-HSA-901032;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-9014325;Reactome: R-HSA-5696394;Reactome: R-HSA-936440;Reactome: R-HSA-110314;Reactome: R-HSA-2565942;Reactome: R-HSA-8866652;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-2979096;Reactome: R-HSA-5689896;Reactome: R-HSA-72689;Reactome: R-HSA-5689880;Reactome: R-HSA-174048;Reactome: R-HSA-9010553;Reactome: R-HSA-5357905;Reactome: R-HSA-156902;Reactome: R-HSA-1236382;Reactome: R-HSA-5655862;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-975163;Reactome: R-HSA-5693565;Reactome: R-HSA-175474;Reactome: R-HSA-192823;Reactome: R-HSA-8856825;Reactome: R-HSA-5675482;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-6782210;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-1295596;Reactome: R-HSA-8876493;Reactome: R-HSA-5684264;Reactome: R-HSA-450321;Reactome: R-HSA-2173788;Reactome: R-HSA-5607761;Reactome: R-HSA-72764;Reactome: R-HSA-6804757;Reactome: R-HSA-349425;Reactome: R-HSA-5696397;Reactome: R-HSA-6781827;Reactome: R-HSA-110320;Reactome: R-HSA-2408557;Reactome: R-HSA-8866654;Reactome: R-HSA-8948747;Reactome: R-HSA-9020702;Reactome: R-HSA-6782135;Reactome: R-HSA-9637628;Reactome: R-HSA-450302;Reactome: R-HSA-9613829;Reactome: R-HSA-5693607;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5654733;Reactome: R-HSA-156827;Reactome: R-HSA-4641257;Reactome: R-HSA-168928;Reactome: R-HSA-5654726;Reactome: R-HSA-6804760;Reactome: R-HSA-2173791;Reactome: R-HSA-187577;Reactome: R-HSA-3134975;Reactome: R-HSA-5689877;Reactome: R-HSA-5668541;Reactome: R-HSA-9636383;Reactome: R-HSA-4608870;Reactome: R-HSA-2691232;Reactome: R-HSA-110312;Reactome: R-HSA-69017;Reactome: R-HSA-2559585;Reactome: R-HSA-5656169;Reactome: R-HSA-912631;Reactome: R-HSA-9013507;Reactome: R-HSA-9615710;Reactome: R-HSA-6783310;Reactome: R-HSA-5654732;Reactome: R-HSA-162588;Reactome: R-HSA-6791226;Reactome: R-HSA-9604323;Reactome: R-HSA-5656121;Reactome: R-HSA-5357956;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-937042;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-445989;Reactome: R-HSA-975110;Reactome: R-HSA-202424;Reactome: R-HSA-2894862;Reactome: R-HSA-8941858;Reactome: R-HSA-917729;Reactome: R-HSA-182971;Reactome: R-HSA-5676590;Reactome: R-HSA-937041;Reactome: R-HSA-180585;Reactome: R-HSA-917937;Reactome: R-HSA-8852276;Reactome: R-HSA-6807004;Reactome: R-HSA-2173795;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-937039;Reactome: R-HSA-6781823;Reactome: R-HSA-6804756;Reactome: R-HSA-5607764;Reactome: R-HSA-8856828;Reactome: R-HSA-209560;Reactome: R-HSA-8854050;Reactome: R-HSA-3769402;Reactome: R-HSA-975956;Reactome: R-HSA-8863795;Reactome: R-HSA-4641263;Reactome: R-HSA-1799339;Reactome: R-HSA-75815;Reactome: R-HSA-69231;Reactome: R-HSA-937072;Reactome: R-HSA-2644606;Reactome: R-HSA-5675221;Reactome: R-HSA-5658442;Reactome: R-HSA-1253288;Reactome: R-HSA-1358803;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-205043;Reactome: R-HSA-69541;Reactome: R-HSA-2122948;Reactome: R-HSA-5358346;Reactome: R-HSA-936964;Reactome: R-HSA-983168;Reactome: R-HSA-2122947;Reactome: R-HSA-382556;Reactome: R-HSA-2559582;Reactome: R-HSA-977225;Reactome: R-HSA-3322077;Reactome: R-HSA-168638;Reactome: R-HSA-5696400;Reactome: R-HSA-168927;Reactome: R-HSA-3785653;Reactome: R-HSA-9646399;Reactome: R-HSA-72706;Reactome: R-HSA-5685942;Reactome: R-HSA-209543;Reactome: R-HSA-975144;Reactome: R-HSA-180534;Reactome: R-HSA-5654727;Reactome: R-HSA-9645460;Reactome: R-HSA-8875360;Reactome: R-HSA-5362768;Reactome: R-HSA-179409;Reactome: R-HSA-975957;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-9033241;Reactome: R-HSA-5689901;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-2672351;Reactome: R-HSA-174490;Reactome: R-HSA-532668;Reactome: R-HSA-400253;Reactome: R-HSA-9013973;Reactome: R-HSA-2559580;Reactome: R-HSA-5696395;Reactome: R-HSA-9633012;Reactome: R-HSA-2173796;Reactome: R-HSA-68949;Reactome: R-HSA-8849469 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"ISG15 antiviral mechanism";"Pink/Parkin Mediated Mitophagy";"TCF dependent signaling in response to WNT";"Neddylation";"ER Quality Control Compartment (ERQC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TICAM1,TRAF6-dependent induction of TAK1 complex";"DNA Damage Recognition in GG-NER";"Negative regulators of DDX58/IFIH1 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of PLK1 Activity at G2/M Transition";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Ovarian tumor domain proteases";"Formation of a pool of free 40S subunits";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of expression of SLITs and ROBOs";"Regulation of TNFR1 signaling";"Peptide chain elongation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Translesion synthesis by POLK";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Assembly Of The HIV Virion";"Viral mRNA Translation";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of necroptotic cell death";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Spry regulation of FGF signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Downregulation of TGF-beta receptor signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Eukaryotic Translation Termination";"Regulation of TP53 Degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Translesion Synthesis by POLH";"Selenocysteine synthesis";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of PTEN localization";"Interleukin-1 signaling";"Dual incision in TC-NER";"Modulation by Mtb of host immune system";"activated TAK1 mediates p38 MAPK activation";"Chaperone Mediated Autophagy";"Processing of DNA double-strand break ends";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Negative regulation of FGFR4 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Degradation of AXIN";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Negative regulation of FGFR1 signaling";"Regulation of TP53 Activity through Methylation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of innate immune responses to cytosolic DNA";"Josephin domain DUBs";"TNFR2 non-canonical NF-kB pathway";"Prevention of phagosomal-lysosomal fusion";"Asymmetric localization of PCP proteins";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Translesion synthesis by REV1";"CDK-mediated phosphorylation and removal of Cdc6";"Oncogene Induced Senescence";"Termination of translesion DNA synthesis";"Regulation of signaling by CBL";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Late endosomal microautophagy";"Fanconi Anemia Pathway";"Negative regulation of FGFR3 signaling";"Budding and maturation of HIV virion";"Major pathway of rRNA processing in the nucleolus and cytosol";"Negative regulation of NOTCH4 signaling";"Translesion synthesis by POLI";"TNFR1-induced NFkappaB signaling pathway";"UCH proteinases";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"IRAK2 mediated activation of TAK1 complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Downstream TCR signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of RUNX3 expression and activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"EGFR downregulation";"NIK-->noncanonical NF-kB signaling";"IKK complex recruitment mediated by RIP1";"Vif-mediated degradation of APOBEC3G";"Iron uptake and transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of MET activity";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"IRAK1 recruits IKK complex";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Activity through Phosphorylation";"CLEC7A (Dectin-1) signaling";"Clathrin-mediated endocytosis";"NF-kB is activated and signals survival";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Deactivation of the beta-catenin transactivating complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Downregulation of ERBB2 signaling";"Regulation of FZD by ubiquitination";"SRP-dependent cotranslational protein targeting to membrane";"Ubiquitin-dependent degradation of Cyclin D";"Cyclin D associated events in G1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of MAPK pathway";"Regulation of RAS by GAPs";"Downregulation of ERBB4 signaling";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"NRIF signals cell death from the nucleus";"Stabilization of p53";"Activated NOTCH1 Transmits Signal to the Nucleus";"Hedgehog ligand biogenesis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Antigen processing: Ubiquitination & Proteasome degradation";"NOTCH1 Intracellular Domain Regulates Transcription";"ABC-family proteins mediated transport";"Senescence-Associated Secretory Phenotype (SASP)";"Amyloid fiber formation";"Glycogen synthesis";"NOD1/2 Signaling Pathway";"Dual Incision in GG-NER";"TICAM1, RIP1-mediated IKK complex recruitment";"Myoclonic epilepsy of Lafora";"Aggrephagy";"GTP hydrolysis and joining of the 60S ribosomal subunit";"HDR through Homologous Recombination (HRR)";"p75NTR recruits signalling complexes";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Vpu mediated degradation of CD4";"Negative regulation of FGFR2 signaling";"Alpha-protein kinase 1 signaling pathway";"InlB-mediated entry of Listeria monocytogenes into host cell";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC-Cdc20 mediated degradation of Nek2A";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Peroxisomal protein import";"Metalloprotease DUBs";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Stimuli-sensing channels";"Membrane binding and targetting of GAG proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Circadian Clock";"TICAM1-dependent activation of IRF3/IRF7";"Oxidative Stress Induced Senescence";"Formation of Incision Complex in GG-NER";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Orc1 removal from chromatin";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1" XP_003487570.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756 "Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation" XP_012237296.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024223611.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_012244241.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762 "Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation" XP_003490220.1 18 Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167158 "Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex" XP_024220412.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003490056.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024224223.1 17 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6783310;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-3371453;KEGG: 05170+2.7.11.1;Reactome: R-HSA-176187;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Fanconi Anemia Pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"mTOR signaling pathway";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of HSF1-mediated heat shock response";"Human immunodeficiency virus 1 infection";"Activation of ATR in response to replication stress";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation" XP_024224622.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972 "Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)" XP_012237445.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_012246112.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024227941.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_012239429.1 5 MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41 "CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism" XP_024220261.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_024222281.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024227896.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_012238020.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_012249736.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003485455.1 9 Reactome: R-HSA-9656255;Reactome: R-HSA-110357;Reactome: R-HSA-9657050;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-5649702;Reactome: R-HSA-9656256 "Defective OGG1 Substrate Binding";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Processing" XP_003489036.1 5 Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-197264 "Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging" XP_003489294.1 4 KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9 "One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines";"One carbon pool by folate" XP_012249650.1 6 MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122 "Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis" XP_024226605.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_003489216.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_024220229.1 6 MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_012245014.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012247160.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012239149.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_003487872.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003493744.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_003492322.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012240299.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_012246248.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710 "HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy" XP_003487799.1 30 Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-198693;Reactome: R-HSA-199418;Reactome: R-HSA-8941332;Reactome: R-HSA-5628897;Reactome: R-HSA-8948751;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804759;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-69202;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-9634638;Reactome: R-HSA-211163;Reactome: R-HSA-111447;Reactome: R-HSA-389513;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8876198;Reactome: R-HSA-1257604;Reactome: R-HSA-9614399;Reactome: R-HSA-389357;Reactome: R-HSA-1358803;Reactome: R-HSA-69656;Reactome: R-HSA-392451;KEGG: 05163+2.7.11.1 "Regulation of TP53 Degradation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Acetylation";"AKT phosphorylates targets in the nucleus";"Negative regulation of the PI3K/AKT network";"RUNX2 regulates genes involved in cell migration";"TP53 Regulates Metabolic Genes";"Regulation of PTEN stability and activity";"Human papillomavirus infection";"Regulation of TP53 Activity through Association with Co-factors";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Cyclin E associated events during G1/S transition";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"AKT-mediated inactivation of FOXO1A";"Activation of BAD and translocation to mitochondria";"CTLA4 inhibitory signaling";"Human immunodeficiency virus 1 infection";"RAB GEFs exchange GTP for GDP on RABs";"PIP3 activates AKT signaling";"Regulation of localization of FOXO transcription factors";"CD28 dependent PI3K/Akt signaling";"Downregulation of ERBB2:ERBB3 signaling";"Cyclin A:Cdk2-associated events at S phase entry";"G beta:gamma signalling through PI3Kgamma";"Human cytomegalovirus infection" XP_012239864.1 57 Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178 "Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Ub-specific processing proteases";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_012249148.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024224549.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024227188.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003484597.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_003485760.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_003493793.1 14 KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-3781;MetaCyc: PWY-5690;MetaCyc: PWY-7279;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302 "Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)" XP_003484734.1 8 Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-141444 "Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024221410.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7214 "Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_012247320.1 19 KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7288 "alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)" XP_024220550.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_012249957.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_012239704.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012247797.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_003487506.1 4 Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_012241003.1 3 Reactome: R-HSA-1660662;MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12 "Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism" XP_012245034.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003487847.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_012248116.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012237977.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024224693.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_024220534.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012242329.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_012237966.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_012241066.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_003488107.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_024222271.1 10 MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15 "Stigma estolide biosynthesis";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_003494034.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_012246845.1 5 Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656237 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2" XP_003485200.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012249863.1 13 Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-422356 "Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Ion homeostasis";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion" XP_012238138.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012246723.1 4 KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27 "Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_012244997.1 9 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Thermogenesis" XP_003490969.1 14 MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433 "Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)" XP_024224337.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003486695.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012243170.2 12 Reactome: R-HSA-9617324;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-399719 "Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors" XP_003490145.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_012240424.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_012246111.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003489554.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_024226346.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012249574.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024223289.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_003490624.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012240425.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_024226347.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012240776.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024227369.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_024224052.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003486310.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_012245111.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_024224507.1 14 MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667 "Plasmalogen biosynthesis";"Synthesis of PA";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I" XP_024224391.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_012236713.1 14 Reactome: R-HSA-418217;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-4086398;KEGG: 04070+3.1.4.11;Reactome: R-HSA-500657;MetaCyc: PWY-7039;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-6367 "G beta:gamma signalling through PLC beta";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Ca2+ pathway";"Phosphatidylinositol signaling system";"Presynaptic function of Kainate receptors";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism" XP_012242114.1 16 Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity" XP_024222940.1 14 MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis" XP_012247973.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012238532.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_003486266.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024226610.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_012248383.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_012241254.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_012246717.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_012248546.1 18 MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4 "Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Synthesis of PA";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism" XP_024221547.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_012243058.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_024220755.1 8 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-7817;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;KEGG: 05235+3.1.3.16;MetaCyc: PWY-5269 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Synthesis of PG";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Cardiolipin biosynthesis II" XP_024223464.1 3 Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144 "Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_012241960.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024227113.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_012236318.1 13 KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802952 "Thermogenesis";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"MAP2K and MAPK activation";"Human immunodeficiency virus 1 infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Signaling by BRAF and RAF fusions" XP_003494005.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012243601.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_003489598.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_024227634.1 4 Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLI" XP_012244587.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003485166.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_024220859.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" XP_012240132.1 8 Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-111458 "Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"Formation of apoptosome" XP_003493554.1 14 Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-1474228;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-6798695;Reactome: R-HSA-205043 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"Degradation of the extracellular matrix";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"NRIF signals cell death from the nucleus" XP_012240397.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_003487158.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_012236800.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_012249295.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_012249637.1 20 MetaCyc: PWY-6837;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7574 "Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II" XP_024228048.1 10 MetaCyc: PWY-6362;MetaCyc: PWY-4661;MetaCyc: PWY-6361;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus" XP_012247398.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024228486.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_024220829.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_024226479.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012249732.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-163615 "Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"PKA activation in glucagon signalling";"PKA activation" XP_024224022.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_003492227.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis" XP_003491400.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_012248776.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_003486113.2 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_012245798.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_024225491.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_012244697.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497 "HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_012242882.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012242672.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003494081.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_003485172.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024220748.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003493059.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003492218.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_024223345.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012245733.1 27 Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690 "Viral Messenger RNA Synthesis";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events" XP_012238700.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_024226368.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012246180.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_024227007.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_024224648.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_024220532.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024227482.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_024226742.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_003494126.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_012236247.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012249632.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_003485589.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_024221628.1 3 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_012238609.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_012236143.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_024221824.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003492401.1 5 KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_003491353.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012247072.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_024225587.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012236430.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_024227778.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012244248.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation" XP_024222464.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_003485656.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012245010.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012247901.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_003491196.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_012248111.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_003485026.1 3 Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)" XP_024226755.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_024220924.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_003490088.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003484771.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012243728.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_012249308.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012237801.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_012240483.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024222473.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024227763.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012244593.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_012241369.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_003487139.1 24 Reactome: R-HSA-392170;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-428930;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418592 "ADP signalling through P2Y purinoceptor 12";"G alpha (i) signalling events";"G alpha (q) signalling events";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (12/13) signalling events";"G-protein activation";"G alpha (z) signalling events";"Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1" XP_003487790.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation" XP_012238017.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_024226338.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_012241340.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" NP_001267051.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_024224526.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012242103.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024221130.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024225101.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_012249762.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_003486007.1 4 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;Reactome: R-HSA-8849175;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)" XP_003486635.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_003486057.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination" XP_024225707.1 8 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Activation of RAC1";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_012236525.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_012247272.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_003486422.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012249821.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024226928.1 34 Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-9639288;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-9648025;Reactome: R-HSA-168276 "Separation of Sister Chromatids";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Amino acids regulate mTORC1";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"HCMV Early Events";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways" XP_003485929.1 4 Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189 "Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)" XP_003486249.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_012243417.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_012243891.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012237240.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024220239.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_003489242.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012243814.1 19 KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00720+2.3.3.8;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-5172;Reactome: R-HSA-71403;Reactome: R-HSA-163765;MetaCyc: PWY-7384 "Propanoate metabolism";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)" XP_012250040.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024221069.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012245301.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003491961.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877 "COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase" XP_012250233.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024225549.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_012246768.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_003494393.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_012245223.2 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_003485059.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024226258.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_012236746.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_003488285.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024224339.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012248918.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint" XP_024223037.1 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_003488850.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_024221960.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012244686.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497 "HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_003485517.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012249751.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_024220804.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024222032.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_012240106.2 5 Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_012244644.1 7 KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-3385;MetaCyc: PWY-7886;Reactome: R-HSA-1483191 "Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Plasmalogen biosynthesis";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC" XP_012249176.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" XP_012239351.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359 "PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation" XP_024228474.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_012245035.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003491125.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024220247.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012249907.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003491807.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" XP_012241643.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012244694.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_024223353.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024221579.1 8 Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68616 "CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication" XP_012236826.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012244902.1 8 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_003489806.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_012247735.1 5 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis" XP_024222980.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_024222605.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012247472.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_003487264.1 5 KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981 "Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)" XP_012249201.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024222168.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-141444;Reactome: R-HSA-196299 "Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade" XP_012246633.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003494404.1 4 Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1" XP_012243759.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER" XP_012238843.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_024225581.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003494114.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012239420.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_024223584.1 4 Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511 "Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination" XP_012242731.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012247887.1 16 Reactome: R-HSA-6811558;Reactome: R-HSA-389357;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-416476;Reactome: R-HSA-8853659;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-912526;Reactome: R-HSA-1433557 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"G alpha (q) signalling events";"RET signaling";"Rho GTPase cycle";"Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT" XP_024222711.1 57 Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902 "Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Regulation of RAS by GAPs";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity" XP_024225489.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012239236.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012244681.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877 "COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase" XP_012241991.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012244584.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_012247857.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_024228104.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012239542.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" XP_012240504.1 17 MetaCyc: PWY-7179;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;Reactome: R-HSA-74217;MetaCyc: PWY-5532;MetaCyc: PWY-5695;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-6644;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1 "Purine deoxyribonucleosides degradation I";"Guanosine nucleotides degradation III";"Purine catabolism";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage";"Neutrophil degranulation";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism" XP_012241849.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024225850.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_003492889.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024224720.1 3 Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B "Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates" XP_003492501.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_024221248.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_003485104.1 7 MetaCyc: PWY-7805;MetaCyc: PWY-6605;Reactome: R-HSA-6798695;MetaCyc: PWY-6610;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807;Reactome: R-HSA-74217 "(aminomethyl)phosphonate degradation";"Adenine and adenosine salvage II";"Neutrophil degranulation";"Adenine salvage";"Purine metabolism";"Glyphosate degradation III";"Purine salvage" XP_012250314.1 4 MetaCyc: PWY-7174;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_003484941.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_012248091.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012249481.1 6 Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368 "Rho GTPase cycle";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_024220703.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024222881.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003492009.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5743 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle" XP_024228148.1 5 MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403 "Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_024226438.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_024220216.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_024220248.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003494464.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_012243607.1 5 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis" XP_003487965.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012239328.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_024223451.1 15 Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616 "HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_003485067.1 14 MetaCyc: PWY-2161;KEGG: 00460+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-181;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-1622;KEGG: 00670+2.1.2.1;MetaCyc: PWY-2201;KEGG: 00630+2.1.2.1 "Folate polyglutamylation";"Cyanoamino acid metabolism";"Metabolism of folate and pterines";"Glycine, serine and threonine metabolism";"Glycine betaine degradation I";"Methane metabolism";"Glycine betaine degradation II (mammalian)";"Photorespiration ";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Formaldehyde assimilation I (serine pathway)";"One carbon pool by folate";"Folate transformations I";"Glyoxylate and dicarboxylate metabolism" XP_012243106.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003484532.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_024228051.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003493535.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012245439.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024224832.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003485284.1 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" XP_012237768.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_024225079.1 7 KEGG: 00230+2.4.2.7;MetaCyc: PWY-6610;Reactome: R-HSA-74217;MetaCyc: PWY-7807;MetaCyc: PWY-7805;Reactome: R-HSA-6798695;MetaCyc: PWY-6605 "Purine metabolism";"Adenine salvage";"Purine salvage";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Neutrophil degranulation";"Adenine and adenosine salvage II" XP_003486008.1 4 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-8849175 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism" XP_003486153.2 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_024220267.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_012241308.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012248114.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_003486585.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_003489434.1 12 MetaCyc: PWY-5872;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-6708;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-5871 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)" XP_012240335.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012238940.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_003487441.1 6 MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622 "Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)" XP_003486227.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_003485073.1 2 KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_012241391.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_003489748.1 29 Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping" XP_012242710.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024224603.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024222814.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_024226086.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_024227036.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135 "Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"MAP2K and MAPK activation" XP_012241968.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003490350.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_003492746.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024225536.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003490338.1 6 Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700 "Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling" XP_024222993.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003490375.1 13 MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1 "Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes" XP_024226953.1 57 Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607761 "Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling" XP_012241277.1 33 Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-170822 "Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_024220472.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_024227463.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012247969.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_003487033.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_003488091.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-532668;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" XP_003484857.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_012247723.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_012236238.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_012245353.1 7 KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897 "Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes" XP_024221062.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_024220841.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_012240688.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_024222604.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012237685.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_024224974.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012236186.1 6 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-416993;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Trafficking of GluR2-containing AMPA receptors";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003490140.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012236368.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_003486840.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_012240627.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003493617.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_003485643.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_012236461.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_024224883.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_012247060.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_024220944.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_012249537.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024223276.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012241368.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012238754.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012250472.1 3 KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286 "One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation" XP_024221843.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_003485946.1 1 MetaCyc: PWY-6938 "NADH repair" XP_012238581.1 8 Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-3371571 "mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"HSF1-dependent transactivation" XP_024226844.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024220854.1 10 MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317 "UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"Galactose metabolism";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)" XP_012241061.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012240849.1 11 Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685942 "Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)" XP_012237765.1 11 Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928 "A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis" XP_024221000.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003493428.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_024223355.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003488549.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024224620.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_024225467.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024224609.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_024221844.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_024224646.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_024224118.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_003489563.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_003487254.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_024222115.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012248960.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_003491398.1 4 KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" XP_024227085.1 17 KEGG: 00680+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-1622;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115 "Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_012249772.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_003490636.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003484601.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_003485294.1 5 KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154 "Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase" XP_012239298.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012249633.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_012249526.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012244933.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012242584.1 7 Reactome: R-HSA-140837;Reactome: R-HSA-381426;Reactome: R-HSA-375276;Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Intrinsic Pathway of Fibrin Clot Formation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Peptide ligand-binding receptors";"Post-translational protein phosphorylation";"Platelet degranulation";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_024225943.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001 "NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade" XP_012244979.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_003488899.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism" XP_024220556.1 11 Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670 "G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway" XP_012240823.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_003491815.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012239674.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_012248140.1 12 MetaCyc: PWY-7385;Reactome: R-HSA-70263;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13 "1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Methane metabolism" XP_012245596.1 15 Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-3769402;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5689896;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262 "S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_024226088.1 15 Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-3769402;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5689896 "APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Deactivation of the beta-catenin transactivating complex";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases" XP_003492146.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_003484788.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012239610.2 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012245834.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_024225876.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001 "Trafficking of AMPA receptors";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Long-term potentiation";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade" XP_003487176.1 9 Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-1362277;Reactome: R-HSA-69017;Reactome: R-HSA-68962;Reactome: R-HSA-68689 "Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_024225676.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003490361.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_012244145.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012246345.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024220821.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003492221.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_012245701.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003493345.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_012247642.1 6 Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3 "Triglyceride catabolism";"Glycerol degradation I";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism" XP_012239012.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_003488712.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_003486506.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-114608 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Platelet degranulation" XP_012244772.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_003493368.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_012241354.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Juniperonate biosynthesis" XP_012239406.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_012243739.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_003489867.1 14 Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-2173788 "HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of TGF-beta receptor signaling" XP_024226595.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" XP_024227156.1 5 KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22 "Sphingolipid metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism" XP_012247890.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5358606;Reactome: R-HSA-5685938;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint" XP_024220238.1 3 MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887 "Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation" XP_024228359.1 4 Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-4420097 "Nephrin family interactions";"Downstream signal transduction";"Activation of RAC1";"VEGFA-VEGFR2 Pathway" XP_012249528.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012250323.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024220828.1 3 MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807 "(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III" XP_003485621.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024222402.1 7 KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-6840;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403 "Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_012247205.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012239152.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012249517.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_012241931.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_024227694.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_003490827.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757 "VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation" XP_024220548.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_003493766.1 6 Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization" XP_003490580.1 26 Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736 "Separation of Sister Chromatids";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"MHC class II antigen presentation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors" XP_024228145.1 4 Reactome: R-HSA-9031525;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-8866427 "NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"VLDLR internalisation and degradation" XP_012246841.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_003489299.1 6 Reactome: R-HSA-674695;Reactome: R-HSA-5632684;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_012239969.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024227574.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012248212.2 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_003493977.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_024226456.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_003492868.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024221391.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation" XP_012248557.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003489947.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385 "mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_003491617.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68827 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex" XP_012242879.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase" XP_003488945.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_012238090.1 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" XP_024226608.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_024224396.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_024225408.1 19 Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026 "Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"VLDL assembly";"Scavenging by Class F Receptors";"LDL remodeling";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Chylomicron assembly";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Chylomicron clearance" XP_012238512.1 11 KEGG: 00720+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-6549;MetaCyc: PWY-5913;MetaCyc: PWY-7124;KEGG: 00480+1.1.1.42 "Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)";"Glutathione metabolism" XP_012236458.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_003490414.1 5 MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-6692 "Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation" XP_003487434.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription" XP_024226408.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_003490277.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7036 "Sciadonate biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II" XP_003488575.1 3 Reactome: R-HSA-8876725;Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60 "Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation" XP_012242299.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_012240090.1 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" XP_003485804.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-442720 "PKA activation";"PKA activation in glucagon signalling";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_012246686.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_024220605.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-983168 "Macroautophagy";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012238430.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003484628.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_003489798.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_024220932.1 3 Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989 "RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" XP_012244720.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012244984.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_012242325.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024222715.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_024227292.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_024225448.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012241116.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_024220268.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_003487650.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_003492576.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012243981.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003489396.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_024223205.1 11 Reactome: R-HSA-69166;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473 "Removal of the Flap Intermediate";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint" XP_024221913.1 5 MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_012243167.1 12 Reactome: R-HSA-5673001;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors" XP_012237113.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-381038;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport" XP_012239517.1 42 Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-9616222;Reactome: R-HSA-9018519;Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-5625886;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-110328;Reactome: R-HSA-5250924;Reactome: R-HSA-1221632;Reactome: R-HSA-977225;Reactome: R-HSA-1912408;Reactome: R-HSA-5334118;Reactome: R-HSA-9609690;Reactome: R-HSA-5693607;Reactome: R-HSA-8936459;Reactome: R-HSA-73728;Reactome: R-HSA-427359;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-606279;Reactome: R-HSA-3214842;Reactome: R-HSA-3214858;Reactome: R-HSA-110331;Reactome: R-HSA-4551638;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Transcriptional regulation of granulopoiesis";"Estrogen-dependent gene expression";"Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"B-WICH complex positively regulates rRNA expression";"Meiotic synapsis";"Amyloid fiber formation";"Pre-NOTCH Transcription and Translation";"DNA methylation";"HCMV Early Events";"Processing of DNA double-strand break ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RNA Polymerase I Promoter Opening";"SIRT1 negatively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDMs demethylate histones";"RMTs methylate histone arginines";"Cleavage of the damaged purine";"SUMOylation of chromatin organization proteins";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence" XP_024222334.1 4 Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356 "TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_012249908.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024226137.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024226505.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012247970.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_024220593.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_024220744.1 6 Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183 "Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_024224376.1 9 Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Neutrophil degranulation";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" XP_003494027.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_012241455.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_003492309.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_024221721.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003492178.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_003493461.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_024220599.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_024220628.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_003491459.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_012236412.1 12 KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"DCC mediated attractive signaling";"PI3K-Akt signaling pathway";"G alpha (q) signalling events";"Human cytomegalovirus infection";"Rho GTPase cycle";"mTOR signaling pathway";"Thermogenesis";"NRAGE signals death through JNK";"Human papillomavirus infection" XP_003491912.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_024225443.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_012240510.1 22 MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-8041;MetaCyc: PWY-7049;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-6433;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7606;MetaCyc: PWY-5080;MetaCyc: PWY-7726 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_012244245.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation" XP_012247572.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003488269.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012247224.1 8 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection" XP_003490427.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024224643.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012249353.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_012245874.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_024227263.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_024220589.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_012245823.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024222545.1 4 Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2 "Selenocysteine synthesis";"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_012244711.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_012236899.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_024227864.1 3 Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_012248642.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_003487512.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_024222341.1 11 MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-6453;Reactome: R-HSA-2029485;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8051 "Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Role of phospholipids in phagocytosis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I" XP_012239498.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_012244943.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_024226356.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024222343.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance" XP_024226594.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_003486126.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003491804.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012242664.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_012250107.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_012244089.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012245734.1 27 Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168271 "Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus" XP_012245713.2 3 Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51 "Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" XP_012248930.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_012244440.1 5 Reactome: R-HSA-446199;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-4755579 "Synthesis of Dolichyl-phosphate";"Androgen biosynthesis";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ" XP_012239918.1 52 Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-5250924;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-76071;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-5578749;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-5617472;Reactome: R-HSA-749476;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-76061;Reactome: R-HSA-73762 "mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Transcriptional regulation by small RNAs";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Initiation" XP_012249527.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012242378.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_012240736.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_003489772.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012249250.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_003487267.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_024224596.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012236513.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024227613.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_024227604.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003486659.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_024225717.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_012240307.1 6 MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-5609978;Reactome: R-HSA-70370 "Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Galactose catabolism" XP_012246953.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012238293.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_003494701.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins" XP_003488295.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_012250057.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_012242986.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012247962.2 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_024228396.1 13 Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5218921 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Effects of PIP2 hydrolysis";"Ion homeostasis";"Ca2+ pathway";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation" XP_012240953.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_003485287.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway" XP_024227522.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_024222260.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_012245841.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012245871.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024223681.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012241505.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_024227813.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_012244671.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_024227759.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_024226633.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012238619.1 7 MetaCyc: PWY-5659;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-882 "GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)" XP_003493212.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003485997.1 14 MetaCyc: PWY-7782;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667 "Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I" XP_012242631.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012247036.1 14 MetaCyc: PWY-8055;MetaCyc: PWY-8053;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-8052 "Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"Synthesis of PC";"Anandamide biosynthesis I";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis" XP_024225285.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024222058.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_024222116.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024228132.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012248457.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_012237089.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_012244682.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012243455.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_003493467.1 10 MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11 "1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Galactose metabolism" XP_003491148.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_012238477.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012241130.1 12 MetaCyc: PWY-5855;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;Reactome: R-HSA-1268020;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6708;MetaCyc: PWY-6978;MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-5871 "Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Mitochondrial protein import";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)" XP_024221886.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events" XP_012237856.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_012246752.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012238152.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA" XP_003492551.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012243511.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_003491839.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012239243.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_012241198.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_024220473.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003487446.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024225107.1 4 KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_012243093.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_012244527.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_012239828.2 5 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_012245829.1 19 Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-202733 "LDL clearance";"Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"LDL remodeling";"Scavenging by Class F Receptors";"VLDL assembly";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Cell surface interactions at the vascular wall" XP_012246957.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024226350.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012237800.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_012237958.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_012243084.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003491775.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_024222581.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_003484595.1 14 Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167242 "Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_012245011.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_024227163.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly" XP_012249222.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_003494534.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012245334.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins" XP_024225409.1 19 Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-8964038 "Scavenging by Class B Receptors";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"LDL remodeling";"VLDL assembly";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"Chylomicron clearance";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL clearance" XP_012239909.1 3 Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13 "G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system" XP_024227945.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_003492764.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024225696.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012245494.1 14 Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-113418 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex" XP_024223133.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003490889.1 4 Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48 "Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_012243976.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_024221508.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_024220444.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012246870.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_012249478.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012244311.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_012240317.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012249386.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_012238279.1 9 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"tRNA modification in the nucleus and cytosol";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation" XP_003492928.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_024224641.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012243178.1 8 Reactome: R-HSA-442982;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244 "Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation" XP_012244934.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003485082.1 9 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695 "TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"Neutrophil degranulation" XP_012237438.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_003491284.1 3 Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627 "O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6" XP_012243683.2 6 Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-1989781 "HDACs deacetylate histones";"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"PPARA activates gene expression" XP_024220660.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012242860.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_003485506.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012249901.1 10 KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;MetaCyc: PWY-6932;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340 "Purine metabolism";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenate reduction";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Monobactam biosynthesis";"Sulfur metabolism";"Sulfate activation for sulfonation" XP_024223946.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012249109.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012241199.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_024224389.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_003490944.1 10 Reactome: R-HSA-9648895;Reactome: R-HSA-72695;Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-382556;Reactome: R-HSA-72731;Reactome: R-HSA-72702 "Response of EIF2AK1 (HRI) to heme deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ABC-family proteins mediated transport";"Recycling of eIF2:GDP";"Ribosomal scanning and start codon recognition" XP_003484811.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012238019.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_012239359.1 10 KEGG: 04070+2.7.1.159;MetaCyc: PWY-6366;MetaCyc: PWY-6362;Reactome: R-HSA-983231;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;Reactome: R-HSA-1855204;MetaCyc: PWY-6365;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.134+2.7.1.159 "Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Factors involved in megakaryocyte development and platelet production";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism" XP_003493609.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003485441.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_024226230.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024226229.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003485295.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_003491890.1 13 Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-419037;Reactome: R-HSA-8948216;Reactome: R-HSA-3000178;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-2214320 "Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Laminin interactions";"Signaling by PDGF";"Integrin cell surface interactions";"NCAM1 interactions";"Collagen chain trimerization";"ECM proteoglycans";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Anchoring fibril formation" XP_012249969.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_024225892.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-111932 "Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Ion homeostasis";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB" XP_012241830.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_024221920.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_012249197.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_012236454.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_024227021.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024220597.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_003492175.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_003491089.2 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_024226132.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012237087.1 1 Reactome: R-HSA-419771 "Opsins" XP_012248037.1 3 Reactome: R-HSA-1474228;Reactome: R-HSA-1592389;Reactome: R-HSA-1442490 "Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases";"Collagen degradation" XP_024224442.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012249635.1 20 MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6 "10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation" XP_012246604.1 14 MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-7124;MetaCyc: PWY-7218 "Rubisco shunt";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_003486107.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003489778.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_024227538.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_003491566.1 14 MetaCyc: PWY-5108;MetaCyc: PWY-5103;KEGG: 00270+2.6.1.42;MetaCyc: PWY-7767;KEGG: 00770+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5101;MetaCyc: PWY-5057;KEGG: 00290+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5104;MetaCyc: PWY-5078;KEGG: 00966+2.6.1.42 "L-isoleucine biosynthesis V";"L-isoleucine biosynthesis III";"Cysteine and methionine metabolism";"L-leucine degradation IV (Stickland reaction)";"Pantothenate and CoA biosynthesis";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis II";"L-valine degradation II";"Valine, leucine and isoleucine biosynthesis";"Valine, leucine and isoleucine degradation";"L-leucine degradation III";"L-isoleucine biosynthesis IV";"L-isoleucine degradation II";"Glucosinolate biosynthesis" XP_024224330.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_012239666.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012239123.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_024221796.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_012236687.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-380972 "Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_003487192.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_012248529.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024220835.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012247153.2 5 MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341 "L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)" XP_003492075.1 4 KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685;Reactome: R-HSA-2393930;KEGG: 00230+3.6.1.17 "Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species";"Phosphate bond hydrolysis by NUDT proteins";"Purine metabolism" XP_003492718.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_024224835.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_024226066.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012238197.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012248104.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_012244708.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024225469.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" XP_003484552.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_024226739.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_003490637.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012240526.1 4 Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;MetaCyc: PWY-6281 "Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_003493114.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_012249784.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_012237688.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445 "Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation" XP_012246539.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003489520.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_012242586.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_003487781.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024221131.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_003493852.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_003491990.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_024223949.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012244635.1 1 Reactome: R-HSA-6804759 "Regulation of TP53 Activity through Association with Co-factors" XP_012241576.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_012249795.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_003487202.3 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_012238863.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7 "Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis" XP_012249586.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012240053.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_003489015.1 6 Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-5609978 "Galactose catabolism";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia" XP_012238692.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012237378.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_012243395.1 4 KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315 "Zeatin biosynthesis";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol" XP_024225677.1 8 MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;MetaCyc: PWY-7391 "Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)" XP_003492869.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_012244280.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_012237406.1 4 MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases" XP_012250326.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024224390.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_012237374.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003487840.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_024227195.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003491784.2 19 Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-432142 "Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"VLDL assembly";"LDL remodeling";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Chylomicron clearance";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Platelet sensitization by LDL" XP_012236098.1 3 Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801 "Glutathione conjugation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)" XP_012237684.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003485637.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003491739.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_012244281.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012238295.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024220483.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012239011.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_024223956.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024220302.1 5 Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796 "Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation" XP_024221266.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003493240.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_024227836.1 11 MetaCyc: PWY-6607;MetaCyc: PWY-6606;MetaCyc: PWY-5695;KEGG: 00983+1.17.3.2;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6538;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-6999;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4+1.17.3.2 "Guanosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Caffeine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Theophylline degradation";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism" XP_024220647.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024225296.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_003494167.1 12 MetaCyc: PWY-7385;Reactome: R-HSA-70263;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13 "1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Methane metabolism" XP_024224186.1 11 Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530 "SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_012247271.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_012246705.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012236757.1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768 "ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_012249147.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012239069.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_003492621.1 4 KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475 "Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_003492402.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024220391.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_012245492.1 14 Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167242 "Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_012249884.1 11 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection" XP_003487706.1 3 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_012248800.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012242163.1 4 Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494 "Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV" XP_024228013.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_012243108.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024227765.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024222737.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_012243221.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_012238592.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012247173.1 17 MetaCyc: PWY-6679;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2 "Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"Fatty acid biosynthesis" XP_012246543.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024221393.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation" XP_012249535.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_024227594.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_012237759.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003490925.1 5 Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_003485561.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_003489949.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_003487960.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_012245041.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012238516.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_012236425.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_012246881.1 6 Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211 "Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling" XP_012247210.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I" XP_003488152.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_003493458.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_003492776.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012241844.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003489669.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_024227476.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003491649.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003491703.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012247884.1 16 Reactome: R-HSA-9009391;Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-6811558;Reactome: R-HSA-1433557;Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-912526;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-194840 "Extra-nuclear estrogen signaling";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by SCF-KIT";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"Interleukin receptor SHC signaling";"Interleukin-7 signaling";"RET signaling";"G alpha (q) signalling events";"Costimulation by the CD28 family";"Rho GTPase cycle" XP_024221394.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_012238513.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003486468.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012243960.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_003493026.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003494658.1 5 Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001 "Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Sialic acid metabolism" XP_012241868.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_024221961.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_024223573.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003484658.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-901042 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle" XP_024222875.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170 "MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_024221463.1 9 MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system" XP_012244730.1 11 Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167290 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation" XP_024223428.1 10 MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15 "Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_012240586.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_024223344.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024227381.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012244672.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_003487886.1 11 KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-6549 "Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"L-glutamine biosynthesis III" XP_012249466.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024224969.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" XP_012238893.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012240040.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_024226951.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024226588.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012241139.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012236505.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024226853.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_003489558.1 4 Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_024223932.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_003494273.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" XP_012241196.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_003488372.2 18 KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-7783 "Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation" XP_012243071.1 5 Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-350054 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway" XP_012245952.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_024220511.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_024223997.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_003489536.1 3 KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661 "Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis" XP_024222640.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024227323.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024228162.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012248087.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_024222189.1 5 Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024224550.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003494147.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_012242618.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012236416.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1362277 "Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex" XP_024220544.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_024223658.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024225218.1 5 MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_003485006.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_003491165.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_003494364.1 7 Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid" XP_024223595.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_012239682.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003491376.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_003486813.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024225871.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952 "Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"RAF activation";"Long-term potentiation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions" XP_012250272.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_012248989.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024222454.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594 "Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events" XP_012240181.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012240819.1 3 Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166 "Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2" XP_024222943.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_012238922.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_012239094.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_012250348.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_003484723.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_024222601.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003488010.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_012236937.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012246162.1 12 MetaCyc: PWY-3801;MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599 "Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Stachyose degradation";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate" XP_012248631.1 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" XP_003488502.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_003487585.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_024227084.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_012244244.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_012239550.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012249439.1 7 MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-1855204 "D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol" XP_024220456.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012240171.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003492742.1 16 Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-1251985;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-1250347;Reactome: R-HSA-6785631;Reactome: R-HSA-1250342;Reactome: R-HSA-1250196;Reactome: R-HSA-1963640;Reactome: R-HSA-9664565;Reactome: R-HSA-1236394;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"Nuclear signaling by ERBB4";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"SHC1 events in ERBB4 signaling";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB4";"Downregulation of ERBB2 signaling";"Signaling by ERBB2" XP_024220466.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024224793.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012243243.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_024225917.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_003484404.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_024225518.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003489128.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_024224912.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003485791.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_012238587.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024222667.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-176407 "APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_024220960.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012238523.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012238006.1 4 MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14 "Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism" XP_012237694.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_024223900.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_003485509.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_003487649.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_003489777.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_024225910.1 9 MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52 "Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis" XP_024224966.1 4 Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8 "Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_024223412.1 4 Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_003486248.2 5 MetaCyc: PWY-5667;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;MetaCyc: PWY-7902 "CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis" XP_003486580.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_012241253.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_024225656.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_003494381.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_012236112.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012236647.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" XP_012239947.1 11 Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_003485374.1 10 Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096 "Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Other glycan degradation";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Sphingolipid metabolism";"HS-GAG degradation" XP_012247538.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003489097.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_024220645.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787 "G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state" XP_012238817.1 5 Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003494923.1 1 Reactome: R-HSA-419771 "Opsins" XP_012239030.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_024227837.1 11 MetaCyc: PWY-6607;KEGG: 00983+1.17.3.2;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-6538;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6999;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6608;MetaCyc: PWY-6596 "Guanosine nucleotides degradation I";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Caffeine degradation III (bacteria, via demethylation)";"Caffeine metabolism";"Theophylline degradation";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I" XP_012238280.1 9 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_024222455.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670 "Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway" XP_024227749.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_012242268.1 5 KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin degradation I (archaea)";"Chitin derivatives degradation" XP_012238115.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024220457.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012243486.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_024221287.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024220978.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_024220941.1 14 MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-399997;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;KEGG: 04070+3.1.4.11;Reactome: R-HSA-434316;Reactome: R-HSA-500657;MetaCyc: PWY-7039;Reactome: R-HSA-112043 "2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Acetylcholine regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Phosphatidylinositol signaling system";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Presynaptic function of Kainate receptors";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events" XP_003486633.1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane" XP_003490895.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024221346.1 9 Reactome: R-HSA-69017;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-1362277;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68949 "CDK-mediated phosphorylation and removal of Cdc6";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Orc1 removal from chromatin" XP_003494144.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_003494911.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024225777.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003485538.1 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" XP_003486209.1 27 Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-165054 "SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA" XP_012242118.1 16 Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569 "Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_024221709.1 7 Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-7282 "Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_003490503.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003484606.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_024226851.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012237687.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003490902.1 5 MetaCyc: PWY-5189;Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis" XP_003488808.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012236617.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_003486197.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012244701.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport" XP_003488328.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_003488276.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_012245896.1 4 MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726 "Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation" XP_024225050.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003488216.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_003493983.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003491524.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012248652.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_024225195.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642 "Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle" XP_012247465.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003487518.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_024220462.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003485170.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024227305.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_003488598.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_024225410.1 19 Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825 "Scavenging by Class B Receptors";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Scavenging by Class F Receptors";"LDL remodeling";"VLDL assembly";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Platelet sensitization by LDL";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis" XP_012238663.2 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_012241762.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003488135.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003491197.1 18 KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7409 "Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Synthesis of PA";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_024222821.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012247016.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024220441.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003484674.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_012250153.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003489516.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2467813 "Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Separation of Sister Chromatids" XP_003492047.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" XP_003490262.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_024220489.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024220418.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003489394.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-176407 "APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_003485913.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-380994 "FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_024224095.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_003492846.1 12 MetaCyc: PWY-7817;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9 "Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_024221994.1 8 KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;Reactome: R-HSA-6798695;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193;MetaCyc: PWY-7181;MetaCyc: PWY-6556;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage" XP_024221065.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024226079.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012248961.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_012245112.1 7 MetaCyc: PWY-6596;MetaCyc: PWY-5695;KEGG: 00230+1.1.1.205;Reactome: R-HSA-73817;MetaCyc: PWY-7221;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205 "Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Neutrophil degranulation";"Drug metabolism - other enzymes" XP_012249759.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_012245674.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_024226765.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_012246954.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_003488763.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003494778.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-210991 "Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Basigin interactions" XP_024224986.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012242215.1 4 KEGG: 00510+2.7.1.108;Reactome: R-HSA-4755583;MetaCyc: PWY-6129;Reactome: R-HSA-446199 "N-Glycan biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate" XP_024221798.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_012236144.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012237115.1 12 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_012237955.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_024225660.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_012239355.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1 "Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Purine metabolism" XP_012247312.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695 "Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Neutrophil degranulation" XP_003488703.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_012246141.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_012240109.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism" XP_003491027.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis" XP_003484731.1 8 Reactome: R-HSA-6787639;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5739;MetaCyc: PWY-66;MetaCyc: PWY-7573 "GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-D-perosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis" XP_003485586.1 15 MetaCyc: PWY-5484;MetaCyc: PWY-2221;Reactome: R-HSA-70171;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-7383 "Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Pyruvate metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_024224141.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_012236399.1 12 KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885 "Thermogenesis";"G alpha (q) signalling events";"Human cytomegalovirus infection";"mTOR signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"DCC mediated attractive signaling" XP_024222380.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_024226751.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_012242925.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003488982.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_003493556.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012245342.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1632852 "mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"Macroautophagy" XP_003489468.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_012241005.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003488588.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events" XP_012241117.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis" XP_024221955.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_003490533.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024220269.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_024226129.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024223218.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012239490.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024226130.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012240107.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_003494061.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_012249462.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_024224392.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_012239788.1 10 MetaCyc: PWY-5849;MetaCyc: PWY-5839;MetaCyc: PWY-5892;MetaCyc: PWY-5895;MetaCyc: PWY-5844;MetaCyc: PWY-5890;Reactome: R-HSA-2142789;MetaCyc: PWY-5891;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163 "Menaquinol-6 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-10 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_024223066.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012242339.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_012238129.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_003490369.1 8 Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-190873 "EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"Gap junction degradation" XP_003489922.1 7 Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024226679.1 4 KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16 "Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_024220409.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024221542.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_003490949.1 6 Reactome: R-HSA-69166;Reactome: R-HSA-110362;Reactome: R-HSA-162594;Reactome: R-HSA-5685939;Reactome: R-HSA-174437;Reactome: R-HSA-5651801 "Removal of the Flap Intermediate";"POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair" XP_024226763.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_003487505.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_012239225.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024225112.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_012244296.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024224708.1 2 KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_024226845.1 4 KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603 "Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine" XP_012250361.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_012244921.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024222606.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024220408.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012242878.1 7 Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690 "Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"HCMV Early Events" XP_024222957.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_003485496.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012236109.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012238593.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012243055.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_012242431.1 11 Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558 "Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_024224784.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012248444.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003490803.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_024220715.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012245304.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003486842.1 25 Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-380270;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Mitotic Prometaphase";"Recruitment of mitotic centrosome proteins and complexes";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Separation of Sister Chromatids" XP_024225018.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003486437.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012240971.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_024227456.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_024220278.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756 "HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation" XP_024223738.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_024224151.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_012240582.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012250199.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_003484498.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_012241370.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_012249013.1 22 Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-389513;Reactome: R-HSA-5358749 "Separation of Sister Chromatids";"Platelet sensitization by LDL";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated" XP_003492136.1 2 Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_024224117.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012246437.1 4 KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726 "Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation" XP_024221324.1 7 Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-110362 "DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"POLB-Dependent Long Patch Base Excision Repair" XP_012242704.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012247469.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024225220.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_024224544.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003491530.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003485606.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_012247019.1 4 KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22 "Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism" XP_024228032.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_024228039.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012242774.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_003489269.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012237189.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_003493891.3 3 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance" XP_012240583.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_024221912.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_012244293.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_012236801.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_003485546.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-8950505;Reactome: R-HSA-9615017;Reactome: R-HSA-2151201;MetaCyc: PWY-6854;Reactome: R-HSA-8862803 "Detoxification of Reactive Oxygen Species";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_003486096.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_003486958.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_012236891.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_003493484.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_003487939.2 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_003485914.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897 "Neutrophil degranulation";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTOR signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes" XP_024228180.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_003491618.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012242686.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012237804.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_012238525.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012248817.1 11 MetaCyc: PWY-6607;MetaCyc: PWY-6606;MetaCyc: PWY-5695;KEGG: 00983+1.17.3.2;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6538;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-6999;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-5497 "Guanosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Caffeine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Theophylline degradation";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)" XP_003490904.1 56 Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-9010553 "Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs" XP_024226915.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024221235.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003489733.2 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_024224893.1 10 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)" XP_024222915.1 6 MetaCyc: PWY-5067;MetaCyc: PWY-622;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;Reactome: R-HSA-3878781 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen storage disease type IV (GBE1)" XP_012245449.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_012240943.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012238561.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_003486331.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-212676 "Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle" XP_003494224.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_003494742.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_012244985.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_012247005.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024220390.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_003485527.1 10 Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167161 "RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation" XP_012246799.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024222263.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_003488958.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003488259.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012246473.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_024220226.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024225015.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024221309.1 24 Reactome: R-HSA-5625740;Reactome: R-HSA-6804757;Reactome: R-HSA-2730905;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218921;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-202424;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;Reactome: R-HSA-354192;KEGG: 05163+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-2871837 "RHO GTPases activate PKNs";"Regulation of TP53 Degradation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"RSK activation";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated cell proliferation";"VEGFR2 mediated vascular permeability";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"Downstream TCR signaling";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"Integrin signaling";"Human cytomegalovirus infection";"Activation of AKT2";"CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation" XP_003493477.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012236824.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024223387.1 9 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Thermogenesis" XP_012248509.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_012249254.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024222673.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_024226657.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_012246164.1 12 MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599 "Sucrose degradation II (sucrose synthase)";"Galactose metabolism";"Stachyose degradation";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate" XP_012239395.1 5 MetaCyc: PWY-7918;MetaCyc: PWY-7919;Reactome: R-HSA-532668;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106 "Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis" XP_003493678.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_003486018.1 5 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis" XP_012237772.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_012249713.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_024220825.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012247281.1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-373080;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838 "Hedgehog 'off' state";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Activation of SMO" XP_024227978.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_012245039.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012245918.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_024227898.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_003493252.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_012245628.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003486908.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport" XP_024220277.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation" XP_012249711.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_003485269.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012241718.1 4 MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662 "Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism" XP_024220547.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_024227143.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012243122.1 6 Reactome: R-HSA-69166;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-5651801 "Removal of the Flap Intermediate";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair" XP_024224098.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_003484411.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_024224149.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_003490956.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_012248453.1 14 MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;Reactome: R-HSA-975634;Reactome: R-HSA-1482788 "Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Acyl chain remodelling of PC" XP_003484491.1 42 MetaCyc: PWY-6863;MetaCyc: PWY-5789;MetaCyc: PWY-5136;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-6945;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-6435;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-7094;MetaCyc: PWY-6944;MetaCyc: PWY-7656;MetaCyc: PWY-7401;MetaCyc: PWY-5109;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00640+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-7779;MetaCyc: PWY-7778;MetaCyc: PWY-7726;KEGG: 00623+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-1361;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00280+4.2.1.17+1.1.1.35 "Pyruvate fermentation to hexanol (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Glutaryl-coa degradation";"Tryptophan metabolism";"Fatty acid degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Butanoate metabolism";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Geraniol degradation";"Limonene and pinene degradation";"Aminobenzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"4-hydroxybenzoate biosynthesis III (plants)";"alpha-Linolenic acid metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid salvage";"Androstenedione degradation";"Spodoptera littoralis pheromone biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fermentation to 2-methylbutanoate";"Butanoate metabolism";"Caprolactam degradation";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Phenylalanine metabolism";"Fatty acid elongation";"Pyruvate fermentation to butanol I";"Methyl tert-butyl ether degradation";"2-methylpropene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Toluene degradation";"Benzoate degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Benzoyl-coa degradation I (aerobic)";"Lysine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Valine, leucine and isoleucine degradation" XP_012241439.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_003487957.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription" XP_003484740.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024226877.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012244531.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_012238599.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012246549.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003489220.1 29 Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-3371511;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-3108214;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;Reactome: R-HSA-912446 "HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"HSF1 activation";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"Meiotic recombination" XP_003488377.1 10 KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-3821 "Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification" XP_012240337.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003491383.1 7 MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205 "Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Neutrophil degranulation";"Drug metabolism - other enzymes" XP_003487378.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012246550.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024223971.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_012246942.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012238857.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_024222742.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_012237176.1 6 MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539 "L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism" XP_003492072.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024227486.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_024224989.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_012244707.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_012249760.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_003487142.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER" XP_003490669.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_012249906.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012236435.1 3 MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_003491298.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012238080.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012247433.1 5 KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-6122;Reactome: R-HSA-73817 "Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis" XP_012236315.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003485066.2 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012244424.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_012246741.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_012245597.1 15 Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-3769402;Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5689896;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262 "S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_012247532.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012239692.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_024224471.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization" XP_024221802.1 4 Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-5674400 "Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer" XP_012241006.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012238511.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_024220217.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_024228397.1 13 Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-112043 "Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"Ion homeostasis";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events" XP_012236548.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024226666.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_024224121.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_024228429.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003485399.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_024220810.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012243615.1 8 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_012241547.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_024222710.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_024225602.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_003486814.2 2 KEGG: 00030+1.1.1.47;Reactome: R-HSA-71384 "Pentose phosphate pathway";"Ethanol oxidation" XP_012249735.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-442720 "Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"PKA activation in glucagon signalling";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_024220328.1 3 Reactome: R-HSA-9609736;Reactome: R-HSA-212676;Reactome: R-HSA-6794361 "Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins" XP_012241652.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_012247968.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_024227785.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_024221211.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012237756.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012238551.1 18 MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4 "Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Synthesis of PA";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism" XP_003485031.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_012249142.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012249014.1 22 Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348 "Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex" XP_012237479.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012240739.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003484938.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_012245827.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003494383.1 4 MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate" XP_012243804.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003487851.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012246612.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_012247750.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_024221018.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_012245195.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-8856828 "Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis" XP_012249870.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024220971.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis" XP_003489127.1 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)" XP_012238977.1 22 Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-195253 "RAF activation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex" XP_024225438.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012246740.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003489677.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_024222992.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012250181.1 5 Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence" XP_012238461.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012244940.1 6 MetaCyc: PWY-6983;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-5663 "Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I" XP_012250141.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_024226790.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_024223574.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024227884.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress" XP_024228062.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681 "G alpha (i) signalling events";"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT" XP_012237989.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_012247809.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_024221414.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7214 "Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_024220250.1 4 KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation" XP_003493634.1 5 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_003489814.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_012244234.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_012248704.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_024225722.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012247133.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012240091.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024226355.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012244346.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-6807505 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes" XP_024224892.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" XP_012247951.1 6 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism" XP_024226353.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024224474.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_024224495.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012242859.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003487768.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003493972.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_003487645.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_024224542.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003486634.1 5 Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-936964;Reactome: R-HSA-936440 "TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling" XP_012243842.1 4 Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494 "Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV" XP_003484937.2 56 Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590 "TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Degradation of AXIN";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling" XP_024226452.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003493593.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003487091.1 4 Reactome: R-HSA-4719360;Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377 "Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_012243973.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_003484434.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_024227066.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024225252.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012245340.1 13 Reactome: R-HSA-2160916;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" XP_003492103.1 5 Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"EPHB-mediated forward signaling" XP_024226436.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_012244328.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003493327.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012249336.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003493996.1 14 MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis I" XP_012241758.1 29 Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_024220531.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012240243.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_024223999.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_024224591.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_003486974.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" XP_024225493.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_012237119.1 2 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_012246113.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024224846.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_024224988.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_012246951.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_003489720.1 10 KEGG: 04151+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05165+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-1660499;Reactome: R-HSA-9027276;KEGG: 05163+2.7.1.153;KEGG: 00562+2.7.1.153 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Human immunodeficiency virus 1 infection";"Synthesis of PIPs at the plasma membrane";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human cytomegalovirus infection";"Inositol phosphate metabolism" XP_012241606.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_024226944.1 17 MetaCyc: PWY-5789;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6679;MetaCyc: PWY-4381 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"Fatty acid biosynthesis";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Propanoate metabolism";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)" XP_024225468.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER" XP_024227317.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012240886.1 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_003492659.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012240230.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_024226165.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012238757.1 11 Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236 "Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Myogenesis";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_012239237.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_024225245.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024220684.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012248022.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012243576.1 12 Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-982772;Reactome: R-HSA-1251985;Reactome: R-HSA-5362798;Reactome: R-HSA-2660826;Reactome: R-HSA-75893;Reactome: R-HSA-177929;Reactome: R-HSA-193692 "Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Growth hormone receptor signaling";"Nuclear signaling by ERBB4";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"TNF signaling";"Signaling by EGFR";"Regulated proteolysis of p75NTR" XP_012238787.1 7 Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16 "Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_024222053.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_024227321.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012249230.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_012242850.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_003488559.2 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_003494084.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003492661.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_003486459.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange" XP_003490946.1 4 Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_003489463.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012238688.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012241447.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_024228400.1 13 Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-112043 "Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events" XP_012245625.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_003489866.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_024223294.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_012243654.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_003490517.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024225212.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_012249332.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_003485359.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_012242722.1 4 MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_003489833.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_012239066.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_003486196.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024224443.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003486056.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-4641258 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"UCH proteinases";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL" XP_024224890.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003489082.1 5 KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-427413 "Cysteine and methionine metabolism";"DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression" XP_024221970.1 4 KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9;Reactome: R-HSA-390247;Reactome: R-HSA-9033241 "Propanoate metabolism";"beta-Alanine metabolism";"Beta-oxidation of very long chain fatty acids";"Peroxisomal protein import" XP_024226122.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_003492927.1 19 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-8876725;Reactome: R-HSA-1799339;Reactome: R-HSA-3214858;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Protein methylation";"SRP-dependent cotranslational protein targeting to membrane";"RMTs methylate histone arginines";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs" XP_012240300.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_024221461.1 9 MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system" XP_024221096.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_024224638.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003484934.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_024220848.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012242883.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024227004.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_024225548.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427 "Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains" XP_012246689.1 4 KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism" XP_012247725.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_024221544.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_003494782.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_024228330.1 20 MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338 "6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)" XP_003492463.2 3 Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_012245624.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_003489651.2 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_024226283.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012248132.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_024220706.1 9 Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-438066 "Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation" XP_012240666.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_003486507.1 15 Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-75955 "Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation" XP_024225451.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012239174.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_012239334.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_012236501.1 9 Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-400206 "Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha" XP_012237579.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Neutrophil degranulation";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_024221489.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012246230.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003485078.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024222382.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_024224251.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_012245507.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_024220943.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_012248450.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024228459.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_012249150.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_024222866.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024224676.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_024220563.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024225737.1 4 Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Mitotic Telophase/Cytokinesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_012236223.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_024225055.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-156711 "G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events" XP_024221672.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_003492533.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_012242701.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024228432.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003493027.1 83 Reactome: R-HSA-912526;Reactome: R-HSA-1295596;Reactome: R-HSA-5654720;Reactome: R-HSA-8856825;Reactome: R-HSA-167044;Reactome: R-HSA-9645135;Reactome: R-HSA-9034864;Reactome: R-HSA-5655253;Reactome: R-HSA-2424491;Reactome: R-HSA-5654695;Reactome: R-HSA-9027284;Reactome: R-HSA-983695;Reactome: R-HSA-1236382;Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-8856828;Reactome: R-HSA-8983432;Reactome: R-HSA-354194;Reactome: R-HSA-5654700;Reactome: R-HSA-5654689;Reactome: R-HSA-5654693;Reactome: R-HSA-180292;Reactome: R-HSA-5637810;Reactome: R-HSA-5654706;Reactome: R-HSA-182971;Reactome: R-HSA-5654712;Reactome: R-HSA-5663213;Reactome: R-HSA-1433557;Reactome: R-HSA-5655291;Reactome: R-HSA-6807004;Reactome: R-HSA-9028335;Reactome: R-HSA-5654688;Reactome: R-HSA-1257604;Reactome: R-HSA-1250347;Reactome: R-HSA-512988;Reactome: R-HSA-5654719;Reactome: R-HSA-1963640;Reactome: R-HSA-9664565;Reactome: R-HSA-8851907;Reactome: R-HSA-375165;Reactome: R-HSA-389359;Reactome: R-HSA-5654699;Reactome: R-HSA-912631;Reactome: R-HSA-391160;Reactome: R-HSA-2871796;Reactome: R-HSA-9028731;Reactome: R-HSA-8853659;Reactome: R-HSA-2179392;Reactome: R-HSA-5654732;Reactome: R-HSA-2730905;Reactome: R-HSA-2029482;Reactome: R-HSA-9607240;Reactome: R-HSA-8853338;Reactome: R-HSA-9026519;Reactome: R-HSA-5654704;Reactome: R-HSA-74749;Reactome: R-HSA-5654726;Reactome: R-HSA-6811558;Reactome: R-HSA-5654727;Reactome: R-HSA-8875360;Reactome: R-HSA-5654710;Reactome: R-HSA-1250196;Reactome: R-HSA-186763;Reactome: R-HSA-1839117;Reactome: R-HSA-179812;Reactome: R-HSA-8875555;Reactome: R-HSA-388841;Reactome: R-HSA-112412;Reactome: R-HSA-8865999;Reactome: R-HSA-5654733;Reactome: R-HSA-5655302;Reactome: R-HSA-8875656;Reactome: R-HSA-2219530;Reactome: R-HSA-8851805;Reactome: R-HSA-180336;Reactome: R-HSA-1963642;Reactome: R-HSA-210993;Reactome: R-HSA-8853334;Reactome: R-HSA-9634285;Reactome: R-HSA-2428933;Reactome: R-HSA-74751;Reactome: R-HSA-1433559;Reactome: R-HSA-2871809 "Interleukin receptor SHC signaling";"Spry regulation of FGF signaling";"PI-3K cascade:FGFR4";"Cargo recognition for clathrin-mediated endocytosis";"Signalling to RAS";"STAT5 Activation";"Activated NTRK3 signals through RAS";"Signaling by FGFR2 in disease";"DAP12 signaling";"PI-3K cascade:FGFR2";"Erythropoietin activates RAS";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"PI3K Cascade";"RAF/MAP kinase cascade";"Clathrin-mediated endocytosis";"Interleukin-15 signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"FRS-mediated FGFR2 signaling";"PI-3K cascade:FGFR1";"FRS-mediated FGFR1 signaling";"GAB1 signalosome";"Constitutive Signaling by EGFRvIII";"FRS-mediated FGFR3 signaling";"EGFR downregulation";"FRS-mediated FGFR4 signaling";"RHO GTPases Activate WASPs and WAVEs";"Signaling by SCF-KIT";"Signaling by FGFR4 in disease";"Negative regulation of MET activity";"Activated NTRK2 signals through PI3K";"SHC-mediated cascade:FGFR1";"PIP3 activates AKT signaling";"SHC1 events in ERBB4 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC-mediated cascade:FGFR4";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"MET activates PI3K/AKT signaling";"NCAM signaling for neurite out-growth";"CD28 dependent Vav1 pathway";"SHC-mediated cascade:FGFR2";"Regulation of signaling by CBL";"Signal regulatory protein family interactions";"FCERI mediated MAPK activation";"Activated NTRK2 signals through FRS2 and FRS3";"RET signaling";"EGFR Transactivation by Gastrin";"Negative regulation of FGFR3 signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of actin dynamics for phagocytic cup formation";"FLT3 Signaling";"Signaling by FGFR3 point mutants in cancer";"Activated NTRK2 signals through RAS";"SHC-mediated cascade:FGFR3";"Signal attenuation";"Negative regulation of FGFR1 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR2 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"PI-3K cascade:FGFR3";"SHC1 events in ERBB2 signaling";"Downstream signal transduction";"Signaling by cytosolic FGFR1 fusion mutants";"GRB2 events in EGFR signaling";"MET activates RAP1 and RAC1";"Costimulation by the CD28 family";"SOS-mediated signalling";"MET activates PTPN11";"Negative regulation of FGFR4 signaling";"Signaling by FGFR1 in disease";"MET receptor recycling";"Constitutive Signaling by Aberrant PI3K in Cancer";"MET activates RAS signaling";"SHC1 events in EGFR signaling";"PI3K events in ERBB2 signaling";"Tie2 Signaling";"Signaling by FGFR3 fusions in cancer";"Constitutive Signaling by Overexpressed ERBB2";"SHC-related events triggered by IGF1R";"Insulin receptor signalling cascade";"Regulation of KIT signaling";"FCERI mediated Ca+2 mobilization" XP_012247179.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012249814.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_024220723.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_003494861.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" XP_024223810.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_012244568.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012250229.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy" XP_003490808.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685 "Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy" XP_024220469.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012246854.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_024220762.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003486881.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_003486629.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_024224865.1 14 MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-1622;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-181 "Glycine betaine degradation II (mammalian)";"Methane metabolism";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Metabolism of folate and pterines";"Cyanoamino acid metabolism";"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Folate transformations I";"Formaldehyde assimilation I (serine pathway)";"One carbon pool by folate";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Photorespiration " XP_024225286.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024221665.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_012248694.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_024225575.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012246927.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012249745.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012236444.1 29 Reactome: R-HSA-6796648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5685938;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5685942;Reactome: R-HSA-6803204;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6803207;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;Reactome: R-HSA-6804760;KEGG: 05163+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-912446;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-3371453 "TP53 Regulates Transcription of DNA Repair Genes";"Human papillomavirus infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"mTOR signaling pathway";"Thermogenesis";"HDR through Single Strand Annealing (SSA)";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Activity through Methylation";"Human cytomegalovirus infection";"Autodegradation of the E3 ubiquitin ligase COP1";"Meiotic recombination";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Human immunodeficiency virus 1 infection";"Stabilization of p53";"Regulation of HSF1-mediated heat shock response" XP_003490690.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_003490120.2 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012238690.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_024220592.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_012244706.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events" XP_012241526.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012241140.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024226062.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_003486446.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012242102.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_003490795.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012239326.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_003487061.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" XP_012247529.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024227923.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024220446.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003492938.1 33 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-6784531 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"tRNA processing in the nucleus" XP_024226337.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_003487871.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003493572.1 12 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4" XP_024221240.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012239096.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_024228079.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024220670.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024224137.1 3 Reactome: R-HSA-4724289;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267 "Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_024226780.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_003491199.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_003490876.1 3 Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-77588 "SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_012247449.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape" XP_024227383.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012240025.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012240519.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003491096.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_012241393.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012248632.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012237565.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024224150.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_012239667.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_012242460.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_003493709.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024222112.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024220707.1 9 Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-9609736 "RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors" XP_003484868.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108 "Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis" XP_024221223.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003486779.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_012237108.1 6 Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_012237321.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_012243888.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003485478.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_024220641.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024227367.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012244039.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_024228137.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_024226400.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202 "Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition" XP_003488933.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024226878.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012237954.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_024225662.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_012246450.2 3 Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331 "Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine" XP_012240229.1 6 MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6731;MetaCyc: PWY-7238;MetaCyc: PWY-6737;Reactome: R-HSA-70221 "Glycogen degradation II";"Starch and sucrose metabolism";"Starch degradation III";"Sucrose biosynthesis II";"Starch degradation V";"Glycogen breakdown (glycogenolysis)" XP_012236500.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_024223433.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_012240938.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_012246832.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_024223678.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012250160.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation" XP_024228037.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_012236725.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003485788.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_024221127.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024223449.1 15 Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616 "HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_024227484.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_024220606.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Macroautophagy";"Neutrophil degranulation" XP_003487216.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_003493696.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024228393.1 14 Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4 "Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism" XP_012245517.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024227031.1 9 Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-114608 "Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Platelet degranulation" XP_003485699.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_003488692.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024227431.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012239950.1 11 Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_024221866.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024224709.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170 "MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_003493067.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_024223130.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024228245.1 5 Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-380994 "Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_024226600.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012245544.1 13 MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-5537 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V" XP_012242478.1 7 Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1 "Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism" XP_012237889.1 14 MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism" XP_024227170.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012243855.2 16 Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_003485036.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_024223902.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012245519.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024220438.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012246161.1 12 Reactome: R-HSA-3322077;MetaCyc: PWY-7343;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9 "Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Sucrose biosynthesis II";"Stachyose degradation";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_012244298.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012247051.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_024227899.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_012236460.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_003494346.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003487596.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003493050.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012243193.1 14 MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis" XP_024220329.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_024224084.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003487651.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_003490395.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_024224562.1 8 MetaCyc: PWY-4984;MetaCyc: PWY-4983;MetaCyc: PWY-5154;Reactome: R-HSA-70635;MetaCyc: PWY-7400;KEGG: 00220+6.3.4.5;KEGG: 00250+6.3.4.5;MetaCyc: PWY-5 "Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Canavanine biosynthesis" XP_003490616.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012239910.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events" XP_024220546.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_003492933.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_012243660.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_024222145.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718 "PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes" XP_024225325.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_003488591.1 6 Reactome: R-HSA-8957275;Reactome: R-HSA-201722;Reactome: R-HSA-5626467;Reactome: R-HSA-3769402;Reactome: R-HSA-2173796;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"Formation of the beta-catenin:TCF transactivating complex";"RHO GTPases activate IQGAPs";"Deactivation of the beta-catenin transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_012247889.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942 "HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)" XP_012236594.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_012240134.1 8 Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111464 "TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Neutrophil degranulation";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_024225749.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012249804.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_003490179.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012244999.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012240701.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_024222059.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_024220833.1 3 MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1 "Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation" XP_012242848.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024222511.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_024221890.1 6 Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_003486087.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163615 "Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"PKA activation" XP_024227002.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_012242630.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024222436.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_024221128.1 12 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes" XP_024228063.1 4 Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594 "TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events" XP_012240423.2 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_024221534.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_024220436.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024226875.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012236997.1 8 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-5689880;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes" XP_024223633.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003489177.1 57 Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-532668;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation" XP_024221968.1 8 Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-165159 "mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Macroautophagy";"mTOR signalling" XP_024228307.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_012236815.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012240834.1 10 Reactome: R-HSA-69205;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7199;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7184;KEGG: 00240+2.1.1.45;MetaCyc: PWY-3841 "G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleosides salvage";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Folate transformations II (plants)" XP_003491722.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012247708.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_024227067.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003489578.1 5 KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006 "Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_012239103.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003489953.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012246859.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_012250024.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012248576.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122 "Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_024222580.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_024223421.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_012236559.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_012238895.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024223295.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_012249436.1 7 MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism" XP_012244174.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012240302.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_012239491.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" XP_024223654.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024221255.1 4 KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation" XP_024226598.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012246518.1 5 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway" XP_012238591.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012248443.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012245870.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-3238698 "Neutrophil degranulation";"WNT ligand biogenesis and trafficking" XP_012247206.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024224470.1 7 Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_024220873.1 12 Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Rho GTPase cycle";"mTOR signaling pathway";"Human cytomegalovirus infection";"G alpha (q) signalling events";"Thermogenesis";"Human papillomavirus infection";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_003492481.2 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_012240401.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012239629.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024222358.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_012242434.1 11 Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196 "ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling" XP_012239122.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_003492891.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024222547.1 4 KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism";"Selenocysteine synthesis" XP_024222191.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003485615.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_012237848.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_024226935.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" XP_024221396.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_024221376.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_024221374.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_003492822.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024225186.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642 "Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_012240128.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003491812.2 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_024226854.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_012237297.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012238573.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_003491838.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_012242022.1 18 Reactome: R-HSA-5362517;KEGG: 00310+1.8.1.4;Reactome: R-HSA-204174;MetaCyc: PWY-5046;KEGG: 00640+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00280+1.8.1.4;Reactome: R-HSA-70268;KEGG: 00020+1.8.1.4;Reactome: R-HSA-70895;KEGG: 00260+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00010+1.8.1.4;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5084;Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00620+1.8.1.4 "Signaling by Retinoic Acid";"Lysine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Propanoate metabolism";"Glycine degradation";"Valine, leucine and isoleucine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Branched-chain amino acid catabolism";"Glycine, serine and threonine metabolism";"Citric acid cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Pyruvate metabolism" XP_024224119.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_003493409.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane" XP_012247536.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012243782.1 8 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_003487151.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_012240632.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_012236268.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_012245990.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_024224848.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_024220305.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_024227104.1 3 KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis" XP_003489403.1 6 KEGG: 00562+3.1.3.64;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.64;MetaCyc: PWY-6580;Reactome: R-HSA-1660517;MetaCyc: PWY-6368 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide degradation" XP_012240362.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_012240922.1 7 Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6470;KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)" XP_024225348.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_024221329.1 4 KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847 "Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones" XP_012239766.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_003487994.1 11 Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-983231 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production" XP_012236286.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012242023.2 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_012242462.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003488001.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_003486157.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_012238393.1 10 Reactome: R-HSA-975634;Reactome: R-HSA-2453864;KEGG: 00230+3.5.2.17;Reactome: R-HSA-977225;MetaCyc: PWY-7849;MetaCyc: PWY-7394;Reactome: R-HSA-3000171;MetaCyc: PWY-5691;Reactome: R-HSA-2453902;Reactome: R-HSA-6798695 "Retinoid metabolism and transport";"Retinoid cycle disease events";"Purine metabolism";"Amyloid fiber formation";"Urate conversion to allantoin III";"Urate conversion to allantoin II";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin I";"The canonical retinoid cycle in rods (twilight vision)";"Neutrophil degranulation" XP_003492956.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_012242709.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003491977.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_003493830.2 3 Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314 "Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex" XP_012243544.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024226010.1 5 KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2 "Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)" XP_012247152.1 4 Reactome: R-HSA-3232142;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1234176 "SUMOylation of ubiquitinylation proteins";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_012240108.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_003485106.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012237802.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_003493639.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012238738.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_012240175.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024220447.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024227324.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024225118.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024221819.1 17 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174414;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair" XP_003484907.1 26 Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-389960;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-9609690 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Separation of Sister Chromatids";"Gap junction assembly";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Mitotic Prometaphase";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"HCMV Early Events" XP_012246292.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-156711 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events" XP_012236515.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024221397.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation" XP_024222676.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_012238076.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_012240097.1 4 KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis" XP_024227003.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_003485688.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_024227790.1 4 Reactome: R-HSA-446210;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906 "Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_012249331.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_012242516.2 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_024227795.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024220527.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003488494.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012248952.1 2 Reactome: R-HSA-2129379;Reactome: R-HSA-189085 "Molecules associated with elastic fibres";"Digestion of dietary carbohydrate" XP_012246039.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_024224002.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_003490864.1 8 MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_012239789.2 10 MetaCyc: PWY-5849;MetaCyc: PWY-5839;MetaCyc: PWY-5895;MetaCyc: PWY-5892;MetaCyc: PWY-5844;MetaCyc: PWY-7996;MetaCyc: PWY-5891;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5890 "Menaquinol-6 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-11 biosynthesis";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-10 biosynthesis" XP_012236325.1 9 Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-9609736 "RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors" XP_012239783.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_003492105.2 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003493195.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_012245262.1 19 Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-936837 "RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Ion homeostasis";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases" XP_012236956.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_024223177.1 3 Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166 "Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2" XP_012241045.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_024227605.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_003493275.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012236985.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_003489017.1 56 Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178 "Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Ub-specific processing proteases";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_024223264.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_003486330.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-212676 "Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle" XP_024225721.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_003492225.1 10 MetaCyc: PWY-7979;Reactome: R-HSA-4719360;Reactome: R-HSA-913709;Reactome: R-HSA-4717374;MetaCyc: PWY-7661;Reactome: R-HSA-162699;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-4719377 "Protein O-mannosylation III (mammals, core M3)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"O-linked glycosylation of mucins";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein N-glycosylation (Haloferax volcanii)";"Synthesis of dolichyl-phosphate mannose";"N-Glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_012237006.1 9 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-113507 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"E2F-enabled inhibition of pre-replication complex formation" XP_012245351.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "mTOR signalling";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" XP_024221267.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012246449.1 3 Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330 "Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_012240677.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003484679.1 10 MetaCyc: PWY-5691;MetaCyc: PWY-7394;Reactome: R-HSA-3000171;Reactome: R-HSA-2453902;Reactome: R-HSA-6798695;Reactome: R-HSA-975634;Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453864;MetaCyc: PWY-7849 "Urate conversion to allantoin I";"Urate conversion to allantoin II";"Non-integrin membrane-ECM interactions";"The canonical retinoid cycle in rods (twilight vision)";"Neutrophil degranulation";"Retinoid metabolism and transport";"Amyloid fiber formation";"Purine metabolism";"Retinoid cycle disease events";"Urate conversion to allantoin III" XP_012243454.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024228196.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012245341.1 13 Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52 "CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis" XP_024227315.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012238305.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_003494440.1 7 Reactome: R-HSA-1474151;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;MetaCyc: PWY-3841;MetaCyc: PWY-6614 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate biosynthesis";"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis" XP_003485878.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_003492954.1 5 Reactome: R-HSA-9033241;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896;Reactome: R-HSA-9033500 "Peroxisomal protein import";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins" XP_003494878.2 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_003490260.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170 "MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_024223108.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_012240550.1 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" XP_012237085.1 1 Reactome: R-HSA-419771 "Opsins" XP_003487562.1 3 KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_024222401.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_012248416.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_003485779.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_003493019.1 5 Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-977225;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399 "Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation";"Josephin domain DUBs";"Aggrephagy" XP_003484619.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-1433559 "Neddylation";"Regulation of KIT signaling" XP_003485975.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_003493551.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_024226397.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_012238294.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024225226.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642 "Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle" XP_024221192.1 6 MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426 "Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_012249437.1 7 MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367 "2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism" XP_024222551.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024222908.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012247202.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_003485125.2 9 MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52 "Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation" XP_024228484.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_003490076.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012242074.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024227264.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_003486736.1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" XP_012236834.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_003488906.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024220370.1 14 Reactome: R-HSA-68877;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-141444 "Mitotic Prometaphase";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_003485475.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024224494.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024226281.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024223018.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012239441.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012239100.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_003486698.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003485626.1 3 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism" XP_024227523.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012247702.1 12 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Macroautophagy";"Human cytomegalovirus infection";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway" XP_003493028.1 52 Reactome: R-HSA-1834949;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-5250924;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-76071;Reactome: R-HSA-167238;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-5617472;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-72086 "Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"mRNA Capping" XP_012238761.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_012247063.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_024226231.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024224057.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_012250142.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_003493717.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003489712.1 7 Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-203927 "Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis" XP_003488213.1 25 Reactome: R-HSA-8939242;Reactome: R-HSA-8941332;Reactome: R-HSA-8935964;Reactome: R-HSA-8939246;Reactome: R-HSA-8939247;Reactome: R-HSA-8941333;Reactome: R-HSA-8931987;Reactome: R-HSA-8939256;Reactome: R-HSA-8941858;Reactome: R-HSA-8941326;Reactome: R-HSA-8936459;Reactome: R-HSA-8939243;Reactome: R-HSA-8939902;Reactome: R-HSA-8941284;Reactome: R-HSA-8951911;Reactome: R-HSA-8951936;Reactome: R-HSA-8934593;Reactome: R-HSA-8939236;Reactome: R-HSA-8949275;Reactome: R-HSA-8878166;Reactome: R-HSA-8940973;Reactome: R-HSA-8877330;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-8939245 "RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in WNT signaling";"Regulation of RUNX3 expression and activity";"RUNX2 regulates bone development";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX2 expression and activity";"RUNX2 regulates chondrocyte maturation";"RUNX3 regulates RUNX1-mediated transcription";"RUNX3 regulates p14-ARF";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX3 Regulates Immune Response and Cell Migration";"Transcriptional regulation by RUNX2";"RUNX2 regulates osteoblast differentiation";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in BCR signaling" XP_012240578.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012244517.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012237589.1 3 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807 "Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III" XP_024225720.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_012244233.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024222603.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_003485265.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012246038.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_024223049.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_012238703.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_003493291.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003487727.1 17 Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-174414;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-69183;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the C-strand of the telomere";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_003488981.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_003487850.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012248818.1 10 MetaCyc: PWY-6362;MetaCyc: PWY-4661;MetaCyc: PWY-6361;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6372;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system" XP_012250448.1 2 Reactome: R-HSA-196299;Reactome: R-HSA-4641262 "Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_012246632.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_003493685.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_003494384.1 11 KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7790;MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+2.1.3.2;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5154;MetaCyc: PWY-7400;KEGG: 00240+3.5.2.3 "Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism" XP_012246683.1 3 Reactome: R-HSA-5694530;Reactome: R-HSA-948021;Reactome: R-HSA-204005 "Cargo concentration in the ER";"Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport" XP_012239175.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_024227155.1 5 KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22 "Sphingolipid metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism" XP_012244236.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation" XP_024223463.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_024227333.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012241543.1 10 KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04151+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3214847 "Relaxin signaling pathway";"Ub-specific processing proteases";"PI3K-Akt signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"HATs acetylate histones" XP_012239593.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012237300.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003493495.1 6 Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5632927;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648 "Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes" XP_012236630.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_012242025.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024226306.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024224541.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003485598.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003493166.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012240975.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase" XP_012248561.1 9 Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-8086;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1 "Biotin transport and metabolism";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" XP_003488798.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012241279.1 33 Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-180746 "Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of DNA replication proteins";"HCMV Early Events";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Nuclear import of Rev protein" XP_003490945.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_024223021.1 9 Reactome: R-HSA-2426168;Reactome: R-HSA-191859;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108 "Activation of gene expression by SREBF (SREBP)";"snRNP Assembly";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_024221220.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012244290.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_003486311.1 11 MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-5675;MetaCyc: PWY-6549;Reactome: R-HSA-8964539 "Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Nitrogen metabolism";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism" XP_024221075.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012245622.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003489344.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003492948.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024227271.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101 "HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation" XP_003490512.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024221001.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003493616.1 20 MetaCyc: PWY-7288;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6 "Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism" XP_024225789.1 18 KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-1622;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37 "Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes" XP_003488049.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_012240973.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024227558.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_012236234.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024226228.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024223512.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012238058.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012247035.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-7782;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-8052 "Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PC";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis" XP_024222660.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012238586.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-3232118 "Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"SUMOylation of transcription factors" XP_003489235.2 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_003488866.1 13 KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916 "Other glycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation" XP_012244716.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation" XP_012237693.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012243209.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601 "(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_003492041.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040 "PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation" XP_012245447.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012241381.1 10 Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695 "RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events" XP_012243502.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024225601.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_003484661.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" XP_003489200.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" XP_012244006.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024220565.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012246614.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_024225038.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012247993.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012243720.1 5 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-917937;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Iron uptake and transport";"UCH proteinases";"TGF-beta receptor signaling activates SMADs" XP_012242391.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012238554.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_012250158.1 18 MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7187;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6 "UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_012244012.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012236716.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012244372.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969 "Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina" XP_024220551.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012249244.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508 "Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_003486802.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_003492909.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_024225214.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_012240223.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024224781.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_012237683.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_024227491.1 10 KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Sphingolipid metabolism";"HS-GAG degradation";"Neutrophil degranulation";"Other glycan degradation";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation" XP_012244214.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_012249510.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_003488533.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_003487103.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024221914.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_003489417.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012237213.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_003494905.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003490061.1 4 KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841 "Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" XP_024226296.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_024223300.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_003487845.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012246843.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_024221094.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012236200.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003491114.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_012238921.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_003493781.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly" XP_024223020.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-191859;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"snRNP Assembly";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression" XP_012239996.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003492578.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_012249054.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_003493683.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_012240663.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_012238691.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_024221118.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012248318.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_012238842.1 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" XP_003486470.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012239974.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_003490998.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003488954.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003490157.1 9 Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-975634 "HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport" XP_012244994.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012240318.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012237774.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_012245662.1 19 Reactome: R-HSA-5627123;Reactome: R-HSA-525793;Reactome: R-HSA-8950505;Reactome: R-HSA-983231;Reactome: R-HSA-114604;Reactome: R-HSA-389359;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-5626467;Reactome: R-HSA-194840;Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-5625970;Reactome: R-HSA-418885;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-5663220 "RHO GTPases activate PAKs";"Myogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade";"CD28 dependent Vav1 pathway";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"RHO GTPases activate IQGAPs";"Rho GTPase cycle";"EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate KTN1";"DCC mediated attractive signaling";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"RHO GTPases Activate Formins" XP_024222366.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012244007.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003493159.1 14 MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-5723;MetaCyc: PWY-1622;MetaCyc: PWY-6901;KEGG: 00010+4.2.1.11;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7218;MetaCyc: PWY-7124 "Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Rubisco shunt";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)" XP_012240718.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_003493404.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_012242881.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024225937.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_012247017.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024222813.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_003489547.1 4 Reactome: R-HSA-4755609;MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87 "Defective DHDDS causes retinitis pigmentosa 59";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis" XP_024220258.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379 "Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events" XP_012243658.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_003486711.2 3 Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989 "TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" XP_003488806.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003486791.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_012239352.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418555 "Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events" XP_003487153.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_024221210.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024226883.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III" XP_024224286.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024221222.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_012246522.1 12 Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-5655302;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Rho GTPase cycle";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"NRAGE signals death through JNK";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_012244619.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_024228485.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_012246916.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_012238040.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_024228038.1 2 Reactome: R-HSA-189085;Reactome: R-HSA-2129379 "Digestion of dietary carbohydrate";"Molecules associated with elastic fibres" XP_012246173.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367 "Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines" XP_024223836.1 4 Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-212300 "SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"DNA methylation";"PRC2 methylates histones and DNA" XP_024225447.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012236635.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024221516.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003486578.2 4 KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation" XP_003486916.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_012240532.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_012250159.1 20 Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756 "G2/M DNA damage checkpoint";"Polymerase switching";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation" XP_012245520.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_003491900.1 3 MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099 "L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling" XP_012244762.1 9 KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_024220788.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003490444.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway" XP_012247858.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_012244601.1 10 KEGG: 05170+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"T cell receptor signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Regulation of TNFR1 signaling";"mTOR signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_003489373.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_024224491.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024223042.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_012239838.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_012248194.1 10 KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23 "Other glycan degradation";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Neutrophil degranulation";"HS-GAG degradation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism" XP_024226035.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012240766.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012249629.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003484389.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003492232.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012249149.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012241057.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_024223152.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_024226775.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-3270619 "Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"IRF3-mediated induction of type I IFN" XP_003489020.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" XP_012239256.1 2 Reactome: R-HSA-73621;Reactome: R-HSA-500753 "Pyrimidine catabolism";"Pyrimidine biosynthesis" XP_012248024.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003493220.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012242326.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012249482.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_012237107.1 6 MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_003493040.1 6 MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-5668 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PG";"Synthesis of PA";"Cardiolipin biosynthesis I" XP_024223282.1 6 MetaCyc: PWY-6368;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64;Reactome: R-HSA-1660517;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.64 "3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" XP_024223354.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024223973.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_024222113.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003488513.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003493767.1 5 Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3 "Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism" XP_012249372.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003490305.2 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_012246995.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024221189.1 6 KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920 "Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)" XP_012239628.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_003484399.1 12 KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;MetaCyc: PWY-6932;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340 "Purine metabolism";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenate reduction";"Sulfite oxidation III";"Monobactam biosynthesis";"Purine metabolism";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Sulfur metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation" XP_003494877.1 5 Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Regulation of the apoptosome activity" XP_003488349.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III" XP_024228210.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024226879.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012248911.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003491845.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_024227332.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024227262.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_003487269.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_024228022.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_012236477.1 6 KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation" XP_024220507.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024228394.1 13 Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509 "VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"Ion homeostasis";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling" XP_012244406.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_024222226.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012243032.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-159236 "SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003487565.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012247494.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003489676.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane" XP_003494712.2 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_003491563.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_024225911.1 8 KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "Oxidative phosphorylation";"Insulin receptor recycling";"Photosynthesis";"Ion channel transport";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" XP_012247302.1 13 MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Purine metabolism" XP_024223134.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012245352.1 7 KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500 "D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle" XP_003492761.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003492550.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_003489855.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_003486273.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-176187;Reactome: R-HSA-5693607 "Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends" XP_003489440.1 44 Reactome: R-HSA-8940973;Reactome: R-HSA-879415;Reactome: R-HSA-6802952;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5673001;Reactome: R-HSA-162658;Reactome: R-HSA-74749;Reactome: R-HSA-6802946;Reactome: R-HSA-5654726;Reactome: R-HSA-6811558;Reactome: R-HSA-9649948;Reactome: R-HSA-5654727;Reactome: R-HSA-5674499;Reactome: R-HSA-5654732;Reactome: R-HSA-2029482;Reactome: R-HSA-2559580;Reactome: R-HSA-445144;Reactome: R-HSA-6802955;Reactome: R-HSA-112409;Reactome: R-HSA-456926;Reactome: R-HSA-1295596;Reactome: R-HSA-202670;Reactome: R-HSA-2871796;Reactome: R-HSA-2559585;Reactome: R-HSA-9634638;Reactome: R-HSA-9627069;Reactome: R-HSA-375165;Reactome: R-HSA-5674135;Reactome: R-HSA-3371453;Reactome: R-HSA-881907;Reactome: R-HSA-5668599;Reactome: R-HSA-5675221;Reactome: R-HSA-8943724;Reactome: R-HSA-444257;Reactome: R-HSA-5663213;Reactome: R-HSA-5654733;Reactome: R-HSA-9635465;Reactome: R-HSA-6802948;Reactome: R-HSA-8939211;Reactome: R-HSA-198753;Reactome: R-HSA-450341;Reactome: R-HSA-170968;Reactome: R-HSA-2559582;Reactome: R-HSA-982772 "RUNX2 regulates osteoblast differentiation";"Advanced glycosylation endproduct receptor signaling";"Signaling by BRAF and RAF fusions";"mTOR signaling pathway";"RAF/MAP kinase cascade";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signal attenuation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of FGFR1 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling downstream of RAS mutants";"Negative regulation of FGFR2 signaling";"Negative feedback regulation of MAPK pathway";"Negative regulation of FGFR3 signaling";"Regulation of actin dynamics for phagocytic cup formation";"Oxidative Stress Induced Senescence";"Signal transduction by L1";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF-independent MAPK1/3 activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Spry regulation of FGF signaling";"ERKs are inactivated";"FCERI mediated MAPK activation";"Oncogene Induced Senescence";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of the apoptosome activity";"NCAM signaling for neurite out-growth";"MAP2K and MAPK activation";"Regulation of HSF1-mediated heat shock response";"Gastrin-CREB signalling pathway via PKC and MAPK";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of MAPK pathway";"Regulation of PTEN gene transcription";"RSK activation";"RHO GTPases Activate WASPs and WAVEs";"Negative regulation of FGFR4 signaling";"Suppression of apoptosis";"Signaling by high-kinase activity BRAF mutants";"ESR-mediated signaling";"ERK/MAPK targets";"Activation of the AP-1 family of transcription factors";"Frs2-mediated activation";"Senescence-Associated Secretory Phenotype (SASP)";"Growth hormone receptor signaling" XP_012247043.1 10 KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171 "Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis" XP_012243195.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_003489494.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_024227794.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003493268.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_003487642.1 16 Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-164939;Reactome: R-HSA-190873;Reactome: R-HSA-416993;Reactome: R-HSA-3928665;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-437239;Reactome: R-HSA-182218 "VLDLR internalisation and degradation";"LDL clearance";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Nef mediated downregulation of CD28 cell surface expression";"Gap junction degradation";"Trafficking of GluR2-containing AMPA receptors";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation" XP_012245198.1 6 MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_003493981.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_024228176.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)" XP_012243501.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012242038.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012247119.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003486344.1 11 Reactome: R-HSA-5668599;Reactome: R-HSA-109704;Reactome: R-HSA-1660499;Reactome: R-HSA-1632852;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660516;KEGG: 04070+2.7.1.137;Reactome: R-HSA-168138;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;MetaCyc: PWY-6352 "RHO GTPases Activate NADPH Oxidases";"PI3K Cascade";"Synthesis of PIPs at the plasma membrane";"Macroautophagy";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide biosynthesis" XP_024225590.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012249818.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012244522.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_012242756.1 11 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-212436;Reactome: R-HSA-383280 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"RORA activates gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway" XP_024223897.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012246826.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_012243943.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012241851.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012250346.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024222215.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_024226802.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024220800.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_003490158.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" XP_024226504.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012245175.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012240587.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_012249465.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003488790.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012248220.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_024225884.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948 "Long-term potentiation";"RAF activation";"Ion homeostasis";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants" XP_012237769.1 5 Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852 "Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Macroautophagy" XP_012248419.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_024220830.1 3 MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807 "(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III" XP_024220264.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_012245954.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_024221901.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012244387.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_003487810.1 13 MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7721;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7102;KEGG: 00900+2.5.1.10+2.5.1.1 "All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Methyl phomopsenoate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis" XP_012241692.1 8 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Recycling pathway of L1";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_003491159.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003492747.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024223757.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003486851.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "Trafficking of GluR2-containing AMPA receptors";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_012239948.1 11 Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948 "Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_003492313.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_024225638.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012236638.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024225338.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_024220465.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_024220572.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012240664.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_003494479.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_024221827.1 3 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843 "Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis" XP_012246994.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024226975.1 8 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_024224446.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_012237695.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003490141.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_024222247.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_012238620.1 7 MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-7586 "Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" XP_012245303.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024220807.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003490536.1 6 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-73762 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_024227349.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003487814.1 28 Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-3371511;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-5685942;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5651801 "Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HSF1 activation";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"HDR through Homologous Recombination (HRR)";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"PCNA-Dependent Long Patch Base Excision Repair" XP_012239363.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_012245853.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003487041.1 8 KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00620+1.1.1.27 "Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism" XP_012240836.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_024228441.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183 "PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes" XP_003493833.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003485983.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway" XP_024224360.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_012238504.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003491225.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024227737.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012238008.1 4 KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14 "Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism" XP_024220689.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012237535.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation" XP_003487931.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_012236352.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_024224652.1 8 Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001 "Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade" XP_003487207.2 4 Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping" XP_003485467.1 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_012238930.2 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_024224133.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012249905.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003490938.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_012247801.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_012247062.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003494736.1 6 Reactome: R-HSA-8951664;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402 "Neddylation";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex" XP_024220950.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012244755.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003484950.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012246114.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024223271.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003486245.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68949 "Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin" XP_024220908.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_003486926.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_024226762.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_003492028.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176412 "Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Phosphorylation of the APC/C" XP_003493597.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_024227762.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012246699.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024227373.1 16 Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-912526;Reactome: R-HSA-1433557 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"RET signaling";"G alpha (q) signalling events";"Rho GTPase cycle";"Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT" XP_012236322.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473 "Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint" XP_003492001.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024221936.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003491534.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_024224614.1 10 Reactome: R-HSA-382556;Reactome: R-HSA-72731;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-381042;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-9648895;Reactome: R-HSA-72695 "ABC-family proteins mediated transport";"Recycling of eIF2:GDP";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Response of EIF2AK1 (HRI) to heme deficiency";"Formation of the ternary complex, and subsequently, the 43S complex" XP_012247720.1 3 Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096 "MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation" XP_024226710.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_012244253.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_024222170.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003492458.1 6 KEGG: 00680+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00750+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00260+2.6.1.52;KEGG: 00270+2.6.1.52 "Methane metabolism";"Serine biosynthesis";"Vitamin B6 metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism" XP_012247879.1 4 Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178 "Integrin cell surface interactions";"Syndecan interactions";"Molecules associated with elastic fibres";"ECM proteoglycans" XP_003487643.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_003493229.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_024228395.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-422356;Reactome: R-HSA-5218921 "DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation" XP_003487399.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024225234.1 13 Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"LDL clearance";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis" XP_024221091.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012248390.1 7 KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363 "Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phytate degradation I";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_003493716.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_024227312.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012244347.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953 "HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation" XP_024224662.1 8 Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324 "Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_003491970.1 3 Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA" XP_024227216.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003491135.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_003492265.1 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2" XP_003485816.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_024222568.1 13 Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-445989;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-937072 "TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_012239697.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024228060.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_012250104.1 3 MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887 "Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation" XP_024221545.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_003493132.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012244029.1 5 MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_012238709.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_024223680.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012247938.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012239751.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_024220485.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012240835.1 10 MetaCyc: PWY-3841;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7184;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7199;Reactome: R-HSA-499943;Reactome: R-HSA-69205;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7198 "Folate transformations II (plants)";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_024223065.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012242051.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_012246144.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69205 "Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription" XP_024224139.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_024220484.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024223364.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-937072 "MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_024224818.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_003487078.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" XP_012239327.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_012244004.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012249438.1 7 KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367 "Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism" XP_012249763.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_024228100.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012250083.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012240295.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" XP_003494920.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024221797.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_012245331.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth" XP_012244173.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024228363.1 9 Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664 "Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Neddylation" XP_012236261.2 6 Reactome: R-HSA-446199;MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33 "Synthesis of Dolichyl-phosphate";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis" XP_024223685.1 33 Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3371453 "Nuclear import of Rev protein";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response" XP_012241639.1 14 Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-2173788;Reactome: R-HSA-9634638;Reactome: R-HSA-3769402;Reactome: R-HSA-141444 "NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"Downregulation of TGF-beta receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Deactivation of the beta-catenin transactivating complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012241060.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024228466.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_024228035.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_024228288.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_003494221.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" XP_012244794.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427 "Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains" XP_003489634.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012244696.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497 "Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_024223954.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012249953.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012240585.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_024220530.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024227040.1 9 Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946 "Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Neutrophil degranulation";"Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants" XP_003492329.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012238223.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_024220311.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024224650.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012242409.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_012241128.1 2 Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7 "Purine salvage";"Purine metabolism" XP_024223682.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024228292.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012249797.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012247025.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_003492667.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_024221905.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_003488612.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_003494408.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" XP_003489229.3 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_003492049.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_024221237.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003484413.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_012249912.1 3 Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_012243457.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_024227873.1 12 MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5856;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-5872;MetaCyc: PWY-7230;Reactome: R-HSA-2142789 "Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis" XP_003489203.1 2 Reactome: R-HSA-375280;Reactome: R-HSA-416476 "Amine ligand-binding receptors";"G alpha (q) signalling events" XP_012245458.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" XP_012241833.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012239017.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_012241707.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_012250100.1 8 MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-74217 "Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine salvage" XP_024225639.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003493116.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024223409.1 9 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_024225942.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165 "RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth" XP_003489937.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024226499.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_024226038.1 14 Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167246 "Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript" XP_012242419.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_012249859.1 4 KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004 "Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I" XP_012242327.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003493871.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_024227706.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_024220600.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_003494008.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_003489350.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_024221513.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_024225071.1 6 Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815 "PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity";"HCMV Early Events";"HDACs deacetylate histones" XP_012243456.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_024226662.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_003491998.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_012240876.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012247315.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_024224372.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024220526.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024221466.1 9 MetaCyc: PWY-6367;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-112043;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system" XP_024223858.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_024221753.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_012244838.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012236282.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_003488296.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_012242368.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024227453.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_003491654.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-202433;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"Generation of second messenger molecules";"RHO GTPases Activate WASPs and WAVEs" XP_012241163.1 5 Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948 "Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants" XP_024227038.1 9 Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946 "Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Neutrophil degranulation";"Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants" XP_024226363.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" XP_012243078.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003494405.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012239145.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_003486765.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_003493109.3 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_003486668.1 16 Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-167287;Reactome: R-HSA-1234176 "Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_003489019.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_003485043.1 4 MetaCyc: PWY-2781;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75 "Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Zeatin biosynthesis" XP_012246720.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024221919.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003491062.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012243233.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012239473.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_012237755.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003489044.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_024224096.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_024227296.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_012246563.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_012246131.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003490474.1 12 MetaCyc: PWY-5132;MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7118 "Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"L-isoleucine biosynthesis V";"Methane metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol" XP_024224509.1 5 Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-1912420 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi" XP_012244596.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_024221969.1 4 KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9 "Propanoate metabolism";"Beta-oxidation of very long chain fatty acids";"Peroxisomal protein import";"beta-Alanine metabolism" XP_003488766.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_024226647.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_012241617.1 56 Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-202424 "CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"UCH proteinases";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling" XP_024222374.1 10 MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-3821;MetaCyc: PWY-7344;MetaCyc: PWY-6397 "Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis" XP_012241873.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003486501.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_024225591.1 7 Reactome: R-HSA-1483213;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-7886;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818 "Synthesis of PE";"Plasmalogen biosynthesis";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)" XP_012240041.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_012237377.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003494178.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024223632.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_012243514.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012242693.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003489993.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_024223575.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003494363.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_024222128.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7 "Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis" XP_024225750.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003490780.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_003487286.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012245852.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003493194.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_003487499.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_024223578.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024225868.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-9609736 "Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"Long-term potentiation";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Ion homeostasis";"RAF activation";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors" XP_012244699.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877 "COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase" XP_012247502.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003491580.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024227808.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_024221904.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_012249327.1 4 MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_024227682.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_024225718.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_003484633.1 3 Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3 "Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism" XP_003490379.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_024228189.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_024226297.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003490586.1 3 Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831 "ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" XP_003490219.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_024227150.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_003492543.1 19 Reactome: R-HSA-4420097;Reactome: R-HSA-389359;Reactome: R-HSA-182971;Reactome: R-HSA-5626467;Reactome: R-HSA-194840;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-5625970;Reactome: R-HSA-418885;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-525793;Reactome: R-HSA-5627123;Reactome: R-HSA-8950505;Reactome: R-HSA-983231;Reactome: R-HSA-114604 "VEGFA-VEGFR2 Pathway";"CD28 dependent Vav1 pathway";"EGFR downregulation";"RHO GTPases activate IQGAPs";"Rho GTPase cycle";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"RHO GTPases activate KTN1";"DCC mediated attractive signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"Myogenesis";"RHO GTPases activate PAKs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade" XP_003486472.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_024225680.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "Neutrophil degranulation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" XP_012239888.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024227407.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_003487811.2 1 Reactome: R-HSA-70171 "Glycolysis" XP_012241083.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK" XP_012244785.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012238865.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7 "Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis" XP_012246191.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012236507.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024225455.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_012243805.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024228054.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012241252.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_012246237.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_024227342.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012242765.1 29 Reactome: R-HSA-6796648;Reactome: R-HSA-5696400;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-167161 "TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation" XP_024228293.1 5 KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2 "Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)" XP_024224706.1 15 Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408 "Ca2+ pathway";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation" XP_024224797.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012244287.1 6 Reactome: R-HSA-983168;Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-8863795;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Downregulation of ERBB2 signaling";"Protein ubiquitination" XP_003486610.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024224753.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_024221060.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_024221095.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_003486207.1 14 Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2467813;Reactome: R-HSA-2565942;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-8854518;Reactome: R-HSA-141444;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Separation of Sister Chromatids";"Regulation of PLK1 Activity at G2/M Transition";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"AURKA Activation by TPX2";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_003490504.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024224970.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism" XP_012246728.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024222550.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012241148.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_024223837.1 4 Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118 "SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation" XP_003488297.3 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_003492910.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003489996.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_012250135.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_012244916.1 8 MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273 "Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis" XP_003490778.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_024226328.1 16 Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-3214847;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"HATs acetylate histones";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends" XP_012243205.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis" XP_012239500.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_024226846.1 182 Reactome: R-HSA-5693565;Reactome: R-HSA-975163;Reactome: R-HSA-175474;Reactome: R-HSA-5357905;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-156902;Reactome: R-HSA-1236382;Reactome: R-HSA-5655862;Reactome: R-HSA-1234176;Reactome: R-HSA-450321;Reactome: R-HSA-8876493;Reactome: R-HSA-5684264;Reactome: R-HSA-72764;Reactome: R-HSA-5607761;Reactome: R-HSA-6804757;Reactome: R-HSA-2173788;Reactome: R-HSA-8856825;Reactome: R-HSA-192823;Reactome: R-HSA-4641258;Reactome: R-HSA-1295596;Reactome: R-HSA-211733;Reactome: R-HSA-6782210;Reactome: R-HSA-1236974;Reactome: R-HSA-5675482;Reactome: R-HSA-8948751;Reactome: R-HSA-901032;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-1169408;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-201681;Reactome: R-HSA-5205685;Reactome: R-HSA-5689896;Reactome: R-HSA-2979096;Reactome: R-HSA-174048;Reactome: R-HSA-5689880;Reactome: R-HSA-72689;Reactome: R-HSA-9014325;Reactome: R-HSA-936440;Reactome: R-HSA-5696394;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-110314;Reactome: R-HSA-2565942;Reactome: R-HSA-8866652;Reactome: R-HSA-5668541;Reactome: R-HSA-9636383;Reactome: R-HSA-5689877;Reactome: R-HSA-2691232;Reactome: R-HSA-4608870;Reactome: R-HSA-168928;Reactome: R-HSA-5654726;Reactome: R-HSA-187577;Reactome: R-HSA-3134975;Reactome: R-HSA-6804760;Reactome: R-HSA-2173791;Reactome: R-HSA-9615710;Reactome: R-HSA-5654732;Reactome: R-HSA-72649;Reactome: R-HSA-162588;Reactome: R-HSA-6791226;Reactome: R-HSA-6783310;Reactome: R-HSA-2559585;Reactome: R-HSA-69017;Reactome: R-HSA-110312;Reactome: R-HSA-9013507;Reactome: R-HSA-5656169;Reactome: R-HSA-912631;Reactome: R-HSA-2408557;Reactome: R-HSA-5696397;Reactome: R-HSA-349425;Reactome: R-HSA-110320;Reactome: R-HSA-6781827;Reactome: R-HSA-5693607;Reactome: R-HSA-68827;Reactome: R-HSA-9613829;Reactome: R-HSA-4641257;Reactome: R-HSA-5654733;Reactome: R-HSA-156827;Reactome: R-HSA-5610780;Reactome: R-HSA-72702;Reactome: R-HSA-8948747;Reactome: R-HSA-8866654;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-6782135;Reactome: R-HSA-9637628;Reactome: R-HSA-8854050;Reactome: R-HSA-3769402;Reactome: R-HSA-975956;Reactome: R-HSA-6781823;Reactome: R-HSA-937039;Reactome: R-HSA-209560;Reactome: R-HSA-8856828;Reactome: R-HSA-6804756;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-69231;Reactome: R-HSA-1799339;Reactome: R-HSA-2644606;Reactome: R-HSA-937072;Reactome: R-HSA-4641263;Reactome: R-HSA-8863795;Reactome: R-HSA-445989;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-975110;Reactome: R-HSA-2894862;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-5357956;Reactome: R-HSA-5656121;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-917937;Reactome: R-HSA-69481;Reactome: R-HSA-6807004;Reactome: R-HSA-2173795;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-182971;Reactome: R-HSA-917729;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-937041;Reactome: R-HSA-179409;Reactome: R-HSA-975957;Reactome: R-HSA-8875360;Reactome: R-HSA-5362768;Reactome: R-HSA-5654727;Reactome: R-HSA-9645460;Reactome: R-HSA-532668;Reactome: R-HSA-72695;Reactome: R-HSA-2672351;Reactome: R-HSA-174490;Reactome: R-HSA-5696395;Reactome: R-HSA-2559580;Reactome: R-HSA-2173796;Reactome: R-HSA-8849469;Reactome: R-HSA-9633012;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-9013973;Reactome: R-HSA-9033241;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-5689901;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-205043;Reactome: R-HSA-69541;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-936964;Reactome: R-HSA-2122948;Reactome: R-HSA-1253288;Reactome: R-HSA-5658442;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-1358803;Reactome: R-HSA-8939902;Reactome: R-HSA-9646399;Reactome: R-HSA-975144;Reactome: R-HSA-180534;Reactome: R-HSA-5685942;Reactome: R-HSA-72706;Reactome: R-HSA-209543;Reactome: R-HSA-977225;Reactome: R-HSA-2122947;Reactome: R-HSA-2559582;Reactome: R-HSA-382556;Reactome: R-HSA-5696400;Reactome: R-HSA-3785653;Reactome: R-HSA-168927;Reactome: R-HSA-168638;Reactome: R-HSA-3322077 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Assembly Of The HIV Virion";"Regulation of TNFR1 signaling";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Peptide chain elongation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Translesion synthesis by POLK";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"InlA-mediated entry of Listeria monocytogenes into host cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Eukaryotic Translation Termination";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of TP53 Degradation";"Downregulation of TGF-beta receptor signaling";"Cargo recognition for clathrin-mediated endocytosis";"Viral mRNA Translation";"Degradation of DVL";"Spry regulation of FGF signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"ER-Phagosome pathway";"Regulation of necroptotic cell death";"Regulation of PTEN stability and activity";"ER Quality Control Compartment (ERQC)";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ISG15 antiviral mechanism";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"TCF dependent signaling in response to WNT";"Pink/Parkin Mediated Mitophagy";"Ovarian tumor domain proteases";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"APC/C:Cdc20 mediated degradation of Cyclin B";"Ub-specific processing proteases";"Formation of a pool of free 40S subunits";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Negative regulators of DDX58/IFIH1 signaling";"DNA Damage Recognition in GG-NER";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of PLK1 Activity at G2/M Transition";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"TNFR2 non-canonical NF-kB pathway";"Prevention of phagosomal-lysosomal fusion";"Josephin domain DUBs";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Asymmetric localization of PCP proteins";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Negative regulation of FGFR1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of innate immune responses to cytosolic DNA";"Regulation of TP53 Activity through Methylation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Late endosomal microautophagy";"Negative regulation of FGFR3 signaling";"Translation initiation complex formation";"Budding and maturation of HIV virion";"Major pathway of rRNA processing in the nucleolus and cytosol";"Fanconi Anemia Pathway";"Oncogene Induced Senescence";"CDK-mediated phosphorylation and removal of Cdc6";"Translesion synthesis by REV1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Termination of translesion DNA synthesis";"Regulation of signaling by CBL";"Selenocysteine synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Autodegradation of the E3 ubiquitin ligase COP1";"Translesion Synthesis by POLH";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of DNA double-strand break ends";"CDT1 association with the CDC6:ORC:origin complex";"Chaperone Mediated Autophagy";"Degradation of AXIN";"Negative regulation of FGFR4 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Degradation of GLI1 by the proteasome";"Ribosomal scanning and start codon recognition";"Regulation of PTEN localization";"E3 ubiquitin ligases ubiquitinate target proteins";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"Dual incision in TC-NER";"Modulation by Mtb of host immune system";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Deactivation of the beta-catenin transactivating complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of TC-NER Pre-Incision Complex";"IRAK1 recruits IKK complex";"NF-kB is activated and signals survival";"Clathrin-mediated endocytosis";"Regulation of TP53 Activity through Phosphorylation";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cyclin D associated events in G1";"SRP-dependent cotranslational protein targeting to membrane";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of FZD by ubiquitination";"Downregulation of ERBB2 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Downstream TCR signaling";"UCH proteinases";"TNFR1-induced NFkappaB signaling pathway";"Translesion synthesis by POLI";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Iron uptake and transport";"G2/M Checkpoints";"Negative regulation of MET activity";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"EGFR downregulation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"IKK complex recruitment mediated by RIP1";"APC-Cdc20 mediated degradation of Nek2A";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of FGFR2 signaling";"Alpha-protein kinase 1 signaling pathway";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of the ternary complex, and subsequently, the 43S complex";"Stimuli-sensing channels";"Membrane binding and targetting of GAG proteins";"Formation of Incision Complex in GG-NER";"Oxidative Stress Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Orc1 removal from chromatin";"Circadian Clock";"TICAM1-dependent activation of IRF3/IRF7";"Peroxisomal protein import";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Metalloprotease DUBs";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"NRIF signals cell death from the nucleus";"Stabilization of p53";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Activated NOTCH1 Transmits Signal to the Nucleus";"Downregulation of ERBB4 signaling";"Regulation of RAS by GAPs";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of RUNX2 expression and activity";"Aggrephagy";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Vpu mediated degradation of CD4";"HDR through Homologous Recombination (HRR)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"p75NTR recruits signalling complexes";"Amyloid fiber formation";"NOTCH1 Intracellular Domain Regulates Transcription";"Senescence-Associated Secretory Phenotype (SASP)";"ABC-family proteins mediated transport";"Dual Incision in GG-NER";"Myoclonic epilepsy of Lafora";"TICAM1, RIP1-mediated IKK complex recruitment";"NOD1/2 Signaling Pathway";"Glycogen synthesis" XP_024226299.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_024227704.1 4 MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;Reactome: R-HSA-964975 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate" XP_012247261.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_012248322.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_024226336.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_024222122.1 9 KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-5744;Reactome: R-HSA-1475029 "Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide" XP_024227039.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952 "Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions" XP_012238527.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003492668.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_024222304.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012239164.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_003488209.1 3 KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403 "Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling" XP_012249955.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012247080.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012244980.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_012243824.1 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism" XP_003490037.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_003489528.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003494270.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_012243562.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012240870.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_024220945.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" XP_003488580.1 24 Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-190861 "EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Aggrephagy";"HCMV Early Events";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Separation of Sister Chromatids";"Gap junction assembly" XP_003489854.1 42 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-427389;Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-110331;Reactome: R-HSA-3214858;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-5625886;Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-1912408;Reactome: R-HSA-1221632;Reactome: R-HSA-5250924;Reactome: R-HSA-110328;Reactome: R-HSA-977225;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-5693607;Reactome: R-HSA-8936459;Reactome: R-HSA-5334118;Reactome: R-HSA-9609690 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"Cleavage of the damaged purine";"RMTs methylate histone arginines";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"G2/M DNA damage checkpoint";"HCMV Late Events";"Cleavage of the damaged pyrimidine";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"Pre-NOTCH Transcription and Translation";"Meiotic synapsis";"B-WICH complex positively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Amyloid fiber formation";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"Processing of DNA double-strand break ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"DNA methylation";"HCMV Early Events" XP_024225099.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003485817.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_024220539.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012242296.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024226821.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012247467.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012240133.1 8 Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-111458 "Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"Formation of apoptosome" XP_012245047.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012250198.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_024223741.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_012249573.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024226591.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024226663.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_024228458.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024222266.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012248555.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012239269.1 10 MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-7344;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-70370 "D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism" XP_012246033.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012249246.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_012247041.1 10 KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861 "Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_012237561.1 6 MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183 "3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_024222049.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_003487808.1 56 Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783 "Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI2 by the proteasome" XP_003490317.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes" XP_003492730.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_012248081.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024226673.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_012243566.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024226606.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_024222280.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003487509.1 4 Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols" XP_012244982.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_003490287.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_024220488.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024227812.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_024224163.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_012247923.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012247933.1 6 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Downregulation of TGF-beta receptor signaling" XP_003488600.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012249712.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_003494772.3 5 KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981 "Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)" XP_012244870.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_012246719.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012236397.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012245759.1 10 Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756 "G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation" XP_024222595.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_003491826.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040 "PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation" XP_003488668.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_012237333.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012242278.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024222932.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_003494421.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_012250244.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_003492094.2 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_024223727.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_003489366.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_003486836.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012247137.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_012246613.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_012242427.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_003493351.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024220655.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359 "PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation" XP_024226267.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_024222820.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024225592.1 7 Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818 "Synthesis of PE";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Choline biosynthesis I";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)" XP_003491650.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_012241011.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024220512.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003492806.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_003493128.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012243495.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_003490694.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_024224120.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_024226943.1 17 KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-6679 "Fatty acid biosynthesis";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Jadomycin biosynthesis" XP_024222088.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_024220560.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012238559.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003489681.1 57 Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-75815 "Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D" XP_012241985.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012249494.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_024220808.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003494456.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012237103.1 6 Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920 "Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)" XP_012250231.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation" XP_003489879.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_024223367.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade" XP_012245872.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_012243949.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_012245566.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003494505.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024226140.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012239187.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012236718.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003487892.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_012242116.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity" XP_024225039.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_003489461.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003484942.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012236138.1 11 Reactome: R-HSA-168138;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;Reactome: R-HSA-1660517;Reactome: R-HSA-109704;Reactome: R-HSA-5668599;Reactome: R-HSA-1660499;Reactome: R-HSA-1632852;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660516 "Toll Like Receptor 9 (TLR9) Cascade";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the late endosome membrane";"PI3K Cascade";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the plasma membrane";"Macroautophagy";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane" XP_012241452.1 17 Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-176408 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase" XP_012238560.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_003493720.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_003492182.1 57 Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895 "Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Ub-specific processing proteases";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis" XP_003486308.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003488690.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_024222778.1 18 Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5689901;Reactome: R-HSA-6796648;Reactome: R-HSA-8953750;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942 "SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Metalloprotease DUBs";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional Regulation by E2F6";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)" XP_012247936.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024225655.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_003484605.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445 "Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation" XP_012245884.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024221679.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012237529.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_012243703.1 6 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-264876 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Insulin processing" XP_024227015.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_003490133.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-383280;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines" XP_003493512.1 5 KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6892 "Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)" XP_024225588.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024221526.1 8 KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1 "Galactose metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_012246952.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012240098.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis" XP_012241923.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_024223265.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_003491320.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane" XP_024221375.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_003485443.1 12 KEGG: 00130+1.14.99.60;MetaCyc: PWY-5871;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-5873;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-5872 "Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)" XP_012241952.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_003494828.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003493726.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863 "RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination" XP_012246796.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024221014.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012245462.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_024225239.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-264642 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_012245583.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_024227612.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012250154.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012246955.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_012249700.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_012247436.1 5 MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6277 "5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_012236712.1 14 Reactome: R-HSA-434316;Reactome: R-HSA-4086398;KEGG: 04070+3.1.4.11;Reactome: R-HSA-399997;Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Ca2+ pathway";"Phosphatidylinositol signaling system";"Acetylcholine regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism" XP_024225381.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-2160916 "AURKA Activation by TPX2";"Hyaluronan uptake and degradation" XP_024226150.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis" XP_012240685.1 4 KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6 "One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_003490383.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-70171;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514 "Chitin degradation I (archaea)";"Glycolysis";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_024228068.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_003487218.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012243757.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_024220266.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_012237320.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_012240623.1 5 MetaCyc: PWY-7511;Reactome: R-HSA-901032;Reactome: R-HSA-381038;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346 "Protein ubiquitination";"ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis" XP_012245958.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003488219.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_024220595.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_012246198.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_024221514.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_024226554.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_024220975.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_024227949.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012247391.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024227190.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024221121.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003494775.1 22 Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated" XP_012236169.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_003485028.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_024224822.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_003484953.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_024225098.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_024221005.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_024227636.1 4 KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817 "Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" XP_024221330.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_012249879.1 11 KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_024223576.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003489176.1 7 Reactome: R-HSA-71064;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61 "Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism" XP_012248922.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress" XP_012247503.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012240112.1 16 Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174178 "Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_003490481.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_024226760.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_012237236.1 7 Reactome: R-HSA-1660516;MetaCyc: PWY-6352;MetaCyc: PWY-6351;Reactome: R-HSA-1660514;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67 "Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_012250038.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003490930.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_024226145.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_003493756.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_003487682.3 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012239271.1 10 MetaCyc: PWY-3821;MetaCyc: PWY-7344;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2 "D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism" XP_012242291.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism" XP_024221070.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_003488307.1 57 Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323 "Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling" XP_012244841.1 7 Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178 "Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans" XP_012236558.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_024220814.1 8 MetaCyc: PWY-6133;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2;KEGG: 00350+1.14.16.2;Reactome: R-HSA-209905;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5049;MetaCyc: PWY-3581 "(S)-reticuline biosynthesis II";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Catecholamine biosynthesis";"Folate biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis I" XP_003488124.1 22 Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated" XP_012237143.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_024224553.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_012250228.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion" XP_003491675.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012245873.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_012237763.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024224546.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024223083.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_012248017.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024226948.1 17 KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6679;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2 "Aflatoxin biosynthesis";"Propanoate metabolism";"Pyruvate metabolism";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes" XP_024223787.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_012244142.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_024228428.1 9 MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983;MetaCyc: PWY-6147;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-7442 "Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis" XP_024223017.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_024227681.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_024220728.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012237569.1 6 Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66 "Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system" XP_003489616.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024227339.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_003487332.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024221510.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_003491901.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_012239142.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_012247882.1 16 Reactome: R-HSA-114604;Reactome: R-HSA-9009391;Reactome: R-HSA-6811558;Reactome: R-HSA-512988;Reactome: R-HSA-2219530;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-1433557;Reactome: R-HSA-416476;Reactome: R-HSA-8853659;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-1266695;Reactome: R-HSA-912526;Reactome: R-HSA-1660499;Reactome: R-HSA-912631 "GPVI-mediated activation cascade";"Extra-nuclear estrogen signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Signaling by SCF-KIT";"G alpha (q) signalling events";"RET signaling";"Rho GTPase cycle";"Costimulation by the CD28 family";"Interleukin-7 signaling";"Interleukin receptor SHC signaling";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL" XP_024226855.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012241127.1 4 Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568 "ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"Attenuation phase" XP_024221311.1 24 Reactome: R-HSA-165158;Reactome: R-HSA-389357;Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;Reactome: R-HSA-5607764;KEGG: 05163+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;Reactome: R-HSA-354192;Reactome: R-HSA-202424;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218921;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-2730905;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5625740 "Activation of AKT2";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"CLEC7A (Dectin-1) signaling";"Human cytomegalovirus infection";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"Integrin signaling";"Downstream TCR signaling";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated cell proliferation";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Role of LAT2/NTAL/LAB on calcium mobilization";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"RSK activation";"PI3K-Akt signaling pathway";"RHO GTPases activate PKNs" XP_003486184.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024221715.1 3 Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5 "Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation" XP_012244958.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_024220411.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003489427.1 14 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-1632852;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5620924;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Macroautophagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"Intraflagellar transport";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_012240036.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_012240270.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_012236884.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_012248480.1 13 MetaCyc: PWY-7184;Reactome: R-HSA-74259;MetaCyc: PWY-7206;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00500+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine catabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Purine metabolism";"Purine metabolism";"Starch and sucrose metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_003490685.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_012246129.2 4 Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750 "Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6" XP_024220574.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012250426.1 7 MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol" XP_003490650.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_024220776.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012239409.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_003486452.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_024225776.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012242239.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662 "TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism" XP_012247464.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012238855.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012246646.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_012245456.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)" XP_024220648.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003493437.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024222994.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003489005.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_024222569.1 13 Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway" XP_024221139.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes" XP_012237212.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_003486241.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_024222099.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_012239417.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_003485525.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_024227322.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012248692.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003489185.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_012244915.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_024224288.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003488330.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012239098.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_024227192.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003492439.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012243471.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_024224759.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_003489512.1 6 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex" XP_024228186.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_012244700.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_024220716.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012236986.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_012250428.1 11 MetaCyc: PWY-5675;Reactome: R-HSA-8964539;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6963;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2 "Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Arginine biosynthesis" XP_012247085.1 6 Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2" XP_003491586.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003487451.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_024225586.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012247136.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012239068.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_012236887.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_003490877.1 7 Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-373753 "RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Nephrin family interactions" XP_024223040.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_024228069.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_012241257.1 7 Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-203927 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis" XP_024226282.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012237591.1 11 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Thermogenesis";"Nonhomologous End-Joining (NHEJ)";"Human papillomavirus infection";"IRF3-mediated induction of type I IFN";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"PI3K-Akt signaling pathway" XP_024223940.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012250112.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003491627.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_024228156.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024225077.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362277 "G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex" XP_003490115.2 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_024224197.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024220731.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_024226946.1 17 MetaCyc: PWY-6679;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-6722 "Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Propanoate metabolism";"Pyruvate metabolism";"Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis" XP_024226453.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024220523.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024226149.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis" XP_024223998.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_003485815.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_024224539.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024228357.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-428540 "Downstream signal transduction";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Activation of RAC1" XP_024220271.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_024220555.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359 "PKA activation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation" XP_012246858.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_003488183.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-168638 "mTOR signaling pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"NOD1/2 Signaling Pathway" XP_012245108.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_003490825.1 14 KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7782 "Glycerolipid metabolism";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis" XP_012249976.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_012250470.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003484632.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003486478.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_024225944.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_024225487.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024222570.1 13 Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-937072 "TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_012250061.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012240277.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_012240985.1 1 Reactome: R-HSA-417973 "Adenosine P1 receptors" XP_012246188.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024223759.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024226796.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003490640.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012241373.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_012248110.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_003486615.2 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_024224610.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_012243109.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012250275.1 9 MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-6118 "CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle" XP_003489365.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_012245368.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_012249858.1 4 MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268 "Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_003492188.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024221209.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_012248023.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003486518.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_003490253.1 12 Reactome: R-HSA-2408550;MetaCyc: PWY-6932;MetaCyc: PWY-6683;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;Reactome: R-HSA-174362 "Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenate reduction";"Assimilatory sulfate reduction III";"Sulfite oxidation III";"Purine metabolism";"Sulfur metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Purine metabolism";"Monobactam biosynthesis";"Selenocompound metabolism";"Transport and synthesis of PAPS" XP_024222118.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012246944.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024224794.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024228126.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_012245691.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012238707.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_003492652.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_003486036.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_003484592.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_012244314.1 52 Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-73772;Reactome: R-HSA-72163;Reactome: R-HSA-427413;Reactome: R-HSA-168325;Reactome: R-HSA-76061;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-167242;Reactome: R-HSA-5617472;Reactome: R-HSA-167238;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-76071;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-5578749;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-73780;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-1834949 "Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Major Pathway";"NoRC negatively regulates rRNA expression";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"Transcriptional regulation by small RNAs";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Chain Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic sensors of pathogen-associated DNA" XP_003484397.1 8 KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-4661;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;MetaCyc: PWY-2301 "Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis" XP_003485726.1 6 MetaCyc: PWY-7820;KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7346 "Teichuronic acid biosynthesis (B. subtilis 168)";"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)" XP_012248440.1 7 Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12;KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-204174 "Pyruvate metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_012242480.1 3 Reactome: R-HSA-420029;Reactome: R-HSA-4608870;Reactome: R-HSA-2173791 "Tight junction interactions";"Asymmetric localization of PCP proteins";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)" XP_003493750.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_003494127.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003494377.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003489462.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012236539.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012242677.1 26 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-3899300;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-8941856;Reactome: R-HSA-8866907;Reactome: R-HSA-201722 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"SUMOylation of transcription cofactors";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"RORA activates gene expression";"RUNX3 regulates NOTCH signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"Formation of the beta-catenin:TCF transactivating complex" XP_012239116.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_003492580.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_012241853.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024220809.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012249240.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_012239917.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport" XP_024225879.1 19 Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001 "Ion homeostasis";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Long-term potentiation";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade" XP_003485995.1 13 MetaCyc: PWY-8086;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism" XP_012240338.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_024226823.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024223395.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_024221312.1 24 KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218921;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-6804757;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;Reactome: R-HSA-389357;Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;Reactome: R-HSA-5607764;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;Reactome: R-HSA-354192;Reactome: R-HSA-202424;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated cell proliferation";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"Thermogenesis";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of TP53 Degradation";"RSK activation";"PI3K-Akt signaling pathway";"RHO GTPases activate PKNs";"Activation of AKT2";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"CLEC7A (Dectin-1) signaling";"Human cytomegalovirus infection";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"Integrin signaling";"Downstream TCR signaling";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection" XP_012247068.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012237324.1 24 KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-202424;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;Reactome: R-HSA-354192;KEGG: 05163+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-2871837;Reactome: R-HSA-5625740;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5674400;Reactome: R-HSA-5218921;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"Downstream TCR signaling";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"Integrin signaling";"Human cytomegalovirus infection";"Activation of AKT2";"CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation";"RHO GTPases activate PKNs";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"PI3K-Akt signaling pathway";"RSK activation";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated cell proliferation";"mTOR signaling pathway";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection" XP_012243801.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003488538.1 2 Reactome: R-HSA-9029569;Reactome: R-HSA-804914 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids" XP_012237953.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_003493025.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553 "Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs" XP_012245595.1 15 Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-3769402;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333 "Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated" XP_024226931.1 4 Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-3232142;Reactome: R-HSA-8951664 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of ubiquitinylation proteins";"Neddylation" XP_003493355.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases" XP_003492264.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736 "CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF activation";"Trafficking of AMPA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors" XP_003489189.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation" XP_024223705.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024225324.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_024227581.1 6 Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205 "TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_003492129.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_012245835.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_012246883.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_012239176.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_003487024.1 4 KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-8040;MetaCyc: PWY-7383 "D-Alanine metabolism";"Alanine racemization";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_012239891.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012238677.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_012248155.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_024224265.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003494457.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012238976.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-141444;Reactome: R-HSA-196299 "Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"RAF activation";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade" XP_012242040.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_003485398.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012239435.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012239829.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012249448.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_024223080.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012239516.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_024223107.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_024224644.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_024223393.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_003494859.1 4 Reactome: R-HSA-1362409;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581 "Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis" XP_012240343.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_012239849.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" XP_012237974.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_003487348.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012249028.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_003486240.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" XP_024225589.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012237005.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_012247260.1 4 KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4 "Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_024223398.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_012245000.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_024221546.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_024224746.1 4 KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_003492629.1 25 Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-381771;Reactome: R-HSA-6814122;Reactome: R-HSA-392451 "Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"G alpha (q) signalling events";"G alpha (i) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G-protein activation";"Thromboxane signalling through TP receptor";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma" XP_024225873.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-9617324 "Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"RAF activation";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Trafficking of AMPA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_012237762.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003485411.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" XP_003484757.1 10 MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7411 "Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)" XP_024220822.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012244704.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events" XP_012236607.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_012239624.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012244526.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_012244913.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_003490030.1 9 MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-112043 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events" XP_003486591.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012245762.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024221224.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012236982.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003487089.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003487629.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_003491548.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_003486295.1 15 Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-912446 "HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination" XP_024224798.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_012236916.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_012239963.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012241255.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_012239508.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation" XP_003494396.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_024221612.1 11 Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3000170;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-202733;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3560801 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Syndecan interactions";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"Cell surface interactions at the vascular wall";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD" XP_012241973.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_003485007.1 10 KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-5689880;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"HATs acetylate histones";"Human papillomavirus infection" XP_003491730.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_003485099.1 3 MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9 "Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_012250109.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_003484989.1 4 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_024225685.1 5 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003490184.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_024223758.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024228071.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_012241240.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003488684.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_003489957.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport" XP_012239061.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_024221541.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_024226945.1 17 MetaCyc: PWY-4381;MetaCyc: PWY-6679;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-5789 "Fatty acid biosynthesis initiation (bacteria and plants)";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Propanoate metabolism";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Fatty acid biosynthesis";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_003488429.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012240347.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142 "Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins" XP_012247488.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012237289.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003492282.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003489507.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003494791.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_003491859.1 10 KEGG: 04151+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5357956;Reactome: R-HSA-5357905;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"T cell receptor signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_012238590.1 5 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_003489593.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_024226798.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024226807.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003489967.2 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_012249841.1 12 MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;MetaCyc: PWY-6683;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4 "Sulfate activation for sulfonation";"Sulfur metabolism";"Sulfur metabolism";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Monobactam biosynthesis";"Purine metabolism";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism" XP_012250003.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_003494014.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003485619.1 6 MetaCyc: PWY-5097;KEGG: 00300+4.3.3.7;KEGG: 00261+4.3.3.7;MetaCyc: PWY-2941;MetaCyc: PWY-8088;MetaCyc: PWY-2942 "L-lysine biosynthesis VI";"Lysine biosynthesis";"Monobactam biosynthesis";"L-lysine biosynthesis II";"Dipicolinate biosynthesis";"L-lysine biosynthesis III" XP_024220451.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003485807.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_012236685.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-380972 "Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_012246931.1 13 Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-437239;Reactome: R-HSA-177504;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-167590 "Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Recycling pathway of L1";"Retrograde neurotrophin signalling";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation" XP_024227693.1 8 KEGG: 00250+6.3.5.5;MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5154;MetaCyc: PWY-7400;KEGG: 00240+3.5.2.3 "Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism" XP_024224083.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_012241372.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_012242459.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_012245707.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_012242279.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024221613.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024222463.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_003493017.1 6 Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_003487902.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012236491.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012238891.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_012236833.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_024226486.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012245123.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_012246958.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_003489178.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination" XP_003491166.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_024220961.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024226936.1 3 Reactome: R-HSA-111465;KEGG: 04660+2.7.10.2;Reactome: R-HSA-1660499 "Apoptotic cleavage of cellular proteins";"T cell receptor signaling pathway";"Synthesis of PIPs at the plasma membrane" XP_024227509.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003488436.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012239700.1 1 MetaCyc: PWY-6938 "NADH repair" XP_012246626.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_024223221.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_012244927.1 5 Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"EPHB-mediated forward signaling" XP_003485623.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012237238.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012244993.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024226136.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012249490.1 6 Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36 "Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Rho GTPase cycle";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system" XP_003491505.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012240735.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_012249979.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression" XP_012239151.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003488987.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_012243928.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024220639.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012236509.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_012239661.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003486788.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024221029.1 6 MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_003488663.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012247898.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_024228157.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024225339.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_003491146.1 32 Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-167162 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"mRNA Capping";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape" XP_024223394.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_003490784.1 7 Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472 "PRC2 methylates histones and DNA";"HCMV Early Events";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_012244703.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497 "HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_024220909.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_003491668.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_012242927.1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Ub-specific processing proteases" XP_003485521.2 4 Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880 "G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases" XP_024227454.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_012250105.1 3 Reactome: R-HSA-6787450;MetaCyc: PWY-7887;MetaCyc: PWY-7892 "tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_024223579.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024224122.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012246040.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003489218.2 5 KEGG: 00640+1.2.4.4;Reactome: R-HSA-70895;MetaCyc: PWY-5046;Reactome: R-HSA-389661;KEGG: 00280+1.2.4.4 "Propanoate metabolism";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"Valine, leucine and isoleucine degradation" XP_003489761.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_012248137.1 11 Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2132295 "Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation" XP_012246341.1 5 Reactome: R-HSA-9630222;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9630221 "Defective NTHL1 substrate binding";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing" XP_012239121.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_012249977.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis" XP_003484921.1 6 MetaCyc: PWY-7077;MetaCyc: PWY-7395;KEGG: 00052+3.5.1.25;MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+3.5.1.25 "N-acetyl-D-galactosamine degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Galactose metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism" XP_003491528.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003489756.1 3 Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320 "HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH" XP_024225695.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003486690.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events" XP_012239831.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_024227730.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012243823.1 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism" XP_024220725.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003486250.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024226037.1 14 Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167152 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_003493033.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024222471.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_003488369.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012240773.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024221962.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_012237757.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024222133.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012243930.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012247995.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024222714.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5545619 "Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN" XP_024224785.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024226646.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_003484585.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012240517.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_003486164.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_012245086.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024226262.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_024226536.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024223839.1 4 Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-212300 "SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"DNA methylation";"PRC2 methylates histones and DNA" XP_012247724.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_024225328.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_012244210.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_003493415.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_024222051.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012239634.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024225216.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_003492915.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_003492841.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_024220793.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_024227330.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012250347.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_003486764.1 5 Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20 "Neutrophil degranulation";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis" XP_003488229.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_003492109.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_024220439.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012247303.1 13 MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism" XP_003487576.1 17 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_012236324.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-69473 "Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint" XP_012247046.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes" XP_012249468.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003489023.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_003486426.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012246010.1 8 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_003487753.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858 "snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines" XP_003489976.1 4 KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_024227767.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012238063.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_003488113.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012241033.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-6799198 "Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis" XP_024222671.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_003486957.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_003484402.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024220459.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012238774.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_003485613.1 7 Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012238462.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_024222555.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_003485691.2 7 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_024227316.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024226791.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_012236093.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8936459 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012239288.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012246443.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695 "rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex" XP_024221395.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_012241862.1 4 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427 "DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins" XP_012237385.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_024226847.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024228152.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012243421.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003487077.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_003485358.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation" XP_024223362.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-937072 "MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_012236264.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012250360.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" XP_024226437.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035 "Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis" XP_024220819.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012245354.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2 "TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis" XP_024224078.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_024224649.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_003494551.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012248319.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_024226207.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_003491818.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_012245949.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_012247012.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024220765.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012248683.1 13 Reactome: R-HSA-8866654;Reactome: R-HSA-382556;Reactome: R-HSA-3371511;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-8876725;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-6798695;Reactome: R-HSA-5689877;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768 "E3 ubiquitin ligases ubiquitinate target proteins";"ABC-family proteins mediated transport";"HSF1 activation";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"Protein methylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"Neutrophil degranulation";"Josephin domain DUBs";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_012247501.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_012245642.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_012238168.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_012238667.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_012247122.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471 "Downstream signal transduction";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_012245021.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012249435.1 15 MetaCyc: PWY-7218;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723 "Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Rubisco shunt" XP_012247168.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024226457.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_012249255.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012243214.1 6 Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1 "Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism" XP_003486272.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_024220422.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012247376.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_003490335.1 14 MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8055 "Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis" XP_012236857.1 1 Reactome: R-HSA-6805567 "Keratinization" XP_024223788.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_024224388.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_003492228.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012238574.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_012239060.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_003485400.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012247203.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_012242910.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-6814122 "Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_003493643.1 17 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012246795.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012242591.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003492450.1 7 Reactome: R-HSA-446193;MetaCyc: PWY-6385;MetaCyc: PWY-5265;Reactome: R-HSA-5633231;MetaCyc: PWY-6470;MetaCyc: PWY-6471;KEGG: 00550+2.4.1.227 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis II (staphylococci)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis" XP_012242466.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_024225866.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244 "Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Ion homeostasis";"RAF activation";"Long-term potentiation" XP_003491916.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_024224159.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024221677.1 4 KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963 "Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I" XP_012243444.1 11 KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-3881;MetaCyc: PWY-7456;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-3861 "Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Mannitol biosynthesis";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II" XP_003486346.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012243655.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_024223955.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024223184.1 4 Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9 "Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" XP_012244177.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024226871.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024220792.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_024226139.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012236678.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003487844.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012242849.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012248663.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_012250151.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_024222989.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_024227635.1 4 Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLI" XP_024224486.1 10 Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Synthesis of PC";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation" XP_012240117.1 14 MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416 "Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_003489710.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_003485380.1 3 Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490 "Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation" XP_024223799.1 4 MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23 "Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism" XP_003484863.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_003486152.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024222235.1 5 Reactome: R-HSA-171007;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172 "p38MAPK events";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"DSCAM interactions" XP_012236717.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024222376.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_024221943.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003494734.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_012238706.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_024220236.1 7 Reactome: R-HSA-4641258;Reactome: R-HSA-201681;Reactome: R-HSA-4086400;Reactome: R-HSA-201688;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5368598 "Degradation of DVL";"TCF dependent signaling in response to WNT";"PCP/CE pathway";"WNT mediated activation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins" XP_024225111.1 7 Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656 "Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry" XP_024224782.1 11 KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-6992;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-3861;MetaCyc: PWY-882;MetaCyc: PWY-7586 "Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"1,5-anhydrofructose degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" XP_003493546.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_003493213.1 52 Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-76071;Reactome: R-HSA-167152;Reactome: R-HSA-76066;Reactome: R-HSA-167238;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-1834949;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-73780;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-76061;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-73772;Reactome: R-HSA-168325;Reactome: R-HSA-427413;Reactome: R-HSA-5617472;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-73779 "Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"RNA Polymerase I Promoter Escape";"Viral Messenger RNA Synthesis";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_012246625.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_003490339.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_024226455.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_024227147.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024226774.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation" XP_012250001.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024225741.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_003485962.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024223528.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_003484778.1 6 Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606 "Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_024222659.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012236714.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012248806.1 14 Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events" XP_024223396.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_024224497.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012247852.1 14 Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4 "Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism" XP_003486702.1 5 Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665 "Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells" XP_012241309.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012249171.1 8 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_012236434.1 3 MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7888 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)" XP_012238760.1 11 Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-8939236;Reactome: R-HSA-525793 "Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis" XP_024221728.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012243320.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024228456.1 14 MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7782;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8055 "Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis" XP_012244688.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_024220590.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_012236219.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003488658.1 8 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_024220974.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_012244685.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012238758.1 11 Reactome: R-HSA-525793;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-69231;Reactome: R-HSA-5693565 "Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_012245923.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012242911.1 10 Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-1483191 "Signal transduction by L1";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Synthesis of PC" XP_012238203.1 3 KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3 "Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism" XP_024220474.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024225665.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_024224080.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_003485616.1 7 Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_012236978.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024222898.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003485262.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_003490151.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_024226961.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_012245687.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012243215.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003491254.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003494282.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_012236221.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012247824.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_012245574.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003492284.1 3 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation" XP_012249880.1 11 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway" XP_012247415.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012245114.1 7 MetaCyc: PWY-6596;MetaCyc: PWY-5695;KEGG: 00230+1.1.1.205;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695 "Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Neutrophil degranulation" XP_012237720.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7 "Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis" XP_003490318.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_012248434.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012236142.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_003488019.3 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024223580.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003487504.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024224473.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_012243202.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs" XP_003485984.1 11 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"DNA replication initiation";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair" XP_012243796.1 7 Reactome: R-HSA-191273;KEGG: 00100+1.3.1.70;MetaCyc: PWY-2541;MetaCyc: PWY-7154;Reactome: R-HSA-9022692;MetaCyc: PWY-6074;MetaCyc: PWY-8026 "Cholesterol biosynthesis";"Steroid biosynthesis";"Phytosterol biosynthesis (plants)";"Ergosterol biosynthesis II";"Regulation of MECP2 expression and activity";"Zymosterol biosynthesis";"Sterol biosynthesis (methylotrophs)" XP_003489234.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012250108.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_003488443.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012240390.1 9 MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263 "Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis" XP_024224081.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024228402.1 13 Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-114508 "Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Ion homeostasis";"Effects of PIP2 hydrolysis" XP_003488644.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_012236396.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024220911.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_012243844.1 4 MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163 "Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism" XP_024227397.1 4 Reactome: R-HSA-901032;KEGG: 00510+3.2.1.113;KEGG: 00513+3.2.1.113;MetaCyc: PWY-7919 "ER Quality Control Compartment (ERQC)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)" XP_024223631.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_012244518.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_012241622.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_012247048.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_003491336.1 19 Reactome: R-HSA-983231;Reactome: R-HSA-114604;Reactome: R-HSA-525793;Reactome: R-HSA-5627123;Reactome: R-HSA-8950505;Reactome: R-HSA-2029482;Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-4420097;Reactome: R-HSA-389359;Reactome: R-HSA-5626467;Reactome: R-HSA-182971;Reactome: R-HSA-194840;Reactome: R-HSA-5687128;Reactome: R-HSA-428543 "Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade";"Myogenesis";"RHO GTPases activate PAKs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of actin dynamics for phagocytic cup formation";"DCC mediated attractive signaling";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"VEGFA-VEGFR2 Pathway";"CD28 dependent Vav1 pathway";"RHO GTPases activate IQGAPs";"EGFR downregulation";"Rho GTPase cycle";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1" XP_012242145.2 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_003486413.1 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" XP_012249467.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024220497.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_012237735.1 5 MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807 "Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_012237293.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003490844.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_024228146.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-8866427;Reactome: R-HSA-9031525;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Protein ubiquitination" XP_012241563.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012238010.1 4 KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621 "Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism" XP_024224016.1 16 Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-2559580 "Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence" XP_003486667.1 16 Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-1234176;Reactome: R-HSA-167287 "Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery" XP_003492036.1 7 KEGG: 04070+3.1.3.36;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204 "Phosphatidylinositol signaling system";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol" XP_012236421.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024226500.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003487141.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012241845.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003486435.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003487488.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012246573.1 5 KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-427413 "Cysteine and methionine metabolism";"DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression" XP_003494708.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins" XP_012243120.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012237567.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_012238436.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024226906.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012240294.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1" XP_003493163.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003493602.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957 "Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012243518.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20 "Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism" XP_012243956.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_012240769.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024220798.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_024223854.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_024222920.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024221597.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003484412.1 4 KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-6798695;Reactome: R-HSA-2162123 "Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)" XP_003487961.1 7 KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-882 "Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)" XP_012238576.1 13 MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-7102;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-7721 "Stellatic acid biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methyl phomopsenoate biosynthesis" XP_012249855.1 9 MetaCyc: PWY-7852;MetaCyc: PWY-6147;MetaCyc: PWY-6703;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-6983;KEGG: 00790+3.5.4.16 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis" XP_024224543.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012246425.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_024223817.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024220487.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012247891.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942 "HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)" XP_012247799.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_003493850.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024220561.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024220840.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_003486742.2 14 Reactome: R-HSA-500657;KEGG: 04070+3.1.4.11;Reactome: R-HSA-4086398;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-418217;Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367 "Presynaptic function of Kainate receptors";"Phosphatidylinositol signaling system";"Ca2+ pathway";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"G beta:gamma signalling through PLC beta";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism" XP_003494459.1 57 Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-2467813 "Degradation of GLI2 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids" XP_003492031.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_003487534.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_024220543.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_003490450.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_012244585.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012239093.1 5 Reactome: R-HSA-5545619;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257 "XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN" XP_012238871.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis" XP_003490571.1 3 KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753 "Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis" XP_012240976.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_012246922.2 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_012237102.1 6 MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143 "Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_024228198.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024227786.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_024227950.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024225664.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_024222390.1 9 Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-68952 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching";"G1/S-Specific Transcription";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"DNA replication initiation" XP_024225472.1 10 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of TNFR1 signaling";"Thermogenesis";"TNFR1-induced NFkappaB signaling pathway";"T cell receptor signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_024223564.1 3 Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569 "ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_003490079.1 5 Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA" XP_024220640.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024226902.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024224017.1 16 Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-2559580 "Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence" XP_012241655.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012241548.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_003493649.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024220480.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024224663.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_003490299.1 34 Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-5696395;Reactome: R-HSA-69231;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-69656;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-69273;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-69202;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-8939236;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6807505 "Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"Formation of Incision Complex in GG-NER";"Cyclin D associated events in G1";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes" XP_024224993.1 5 KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_003490419.1 6 KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;MetaCyc: PWY-6174 "Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)" XP_024222336.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_012237890.1 14 Reactome: R-HSA-1482788;Reactome: R-HSA-975634;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4 "Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism" XP_012239124.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_012239851.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012243894.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024226354.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003489533.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922 "Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium" XP_003493965.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_003486080.2 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_012239125.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_012242058.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012244728.1 11 Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167290 "RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation" XP_012244251.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation" XP_024222812.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_003486554.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_003485513.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024220471.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003492033.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012238486.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_003489666.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012241064.1 7 Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15 "tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012245177.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012241078.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_012247011.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024221716.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68689 "Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_024222456.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359 "G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation" XP_003488100.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_024223450.1 15 Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938 "Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)" XP_024227026.1 3 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_012238607.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_012246933.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_012243218.1 5 MetaCyc: PWY-7210;Reactome: R-HSA-6798695;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Purine metabolism" XP_012242067.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_012239178.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_024222532.1 4 MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Selenocysteine synthesis" XP_012246620.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003494590.2 4 MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59 "N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" XP_024220514.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012238231.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_024227429.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024225742.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024224845.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_003485953.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024225492.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_012238428.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012245505.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024223029.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003485601.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012244809.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012245295.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_003487270.1 7 Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505 "Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_003487515.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024226747.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003494370.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_012249525.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003488551.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_024227708.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012239067.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_024222949.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1" XP_003490858.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003485193.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829 "SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Aggrephagy";"Chaperone Mediated Autophagy" XP_024227804.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_012237369.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_024226726.1 7 KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism" XP_024225393.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012248280.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012243802.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003486606.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003491662.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_012241256.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_012246602.1 12 KEGG: 00720+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5132;MetaCyc: PWY-5108;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118 "Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pyruvate metabolism";"Chitin degradation to ethanol" XP_024224613.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion" XP_012243054.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_012239014.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_024227092.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_012243512.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003486453.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024224612.1 24 Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-68877 "Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Aggrephagy";"HCMV Early Events";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Gap junction assembly";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Mitotic Prometaphase" XP_012247039.1 10 Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11 "Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism" XP_012240381.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-432040 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"PKA activation in glucagon signalling";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_012247919.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012239861.1 12 Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex" XP_024227755.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003493660.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003489886.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003493160.1 7 KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363 "Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phytate degradation I";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_003492708.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I" XP_024226391.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012244683.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_024224510.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012237777.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"TBC/RABGAPs" XP_003493966.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_003490473.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024225788.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012242062.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_012249630.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_024220721.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_024227229.1 6 Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-4261 "Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol degradation I" XP_024222850.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_003490751.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" XP_003485646.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_003485654.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_024223480.1 11 Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5696400 "PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER" XP_003492943.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602 "(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_024220928.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012247825.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_012242267.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_012241312.1 6 Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13 "Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system" XP_012243197.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7619 "Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Juniperonate biosynthesis" XP_012246168.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_024224435.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_012241649.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012246110.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024220541.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_003488955.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003486944.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003494086.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400 "PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer" XP_024224440.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012238092.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_003484843.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_003494510.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_024224776.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012244783.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012246343.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012243995.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003494095.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_012249521.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_003487068.1 7 Reactome: R-HSA-110362;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-5685939;Reactome: R-HSA-2173795;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" XP_024227191.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024223360.1 3 KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662;MetaCyc: PWY-7277 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)" XP_024221548.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_024222945.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003487475.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_024223585.1 4 Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-9020702 "IRAK1 recruits IKK complex";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling" XP_024225740.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_024225289.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003486450.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012246809.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_012248435.1 12 KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8051 "Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I" XP_024227138.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_012241147.1 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_012241846.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024222543.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012245059.1 9 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_024228329.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003494410.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012239136.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086 "Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping" XP_003491605.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase" XP_012248326.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012241974.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_024220542.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012246148.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_003490754.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003491962.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_003485435.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_012243611.1 10 Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends" XP_003486535.2 3 Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)" XP_012247573.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012246348.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012244936.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_012238699.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012238748.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024224000.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_024221183.1 3 Reactome: R-HSA-69273;Reactome: R-HSA-418594;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"G alpha (i) signalling events";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_012248204.1 10 KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Other glycan degradation";"Glycosaminoglycan degradation" XP_024226142.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_024226711.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_012250102.1 10 Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-427413 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression" XP_024226859.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes" XP_012245002.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_003492917.1 11 Reactome: R-HSA-167161;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73776 "HIV Transcription Initiation";"Ub-specific processing proteases";"Transcription of the HIV genome";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape" XP_024225377.1 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_012244541.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_003491659.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024224157.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003490594.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_003488667.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_003485819.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339 "Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane" XP_012249529.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012240396.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012248420.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_003486447.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_024222009.1 3 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions" XP_024225453.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024226779.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012239407.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_003488304.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167161 "RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation" XP_012242866.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6807505 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes" XP_003488469.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_024224199.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012247609.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003487899.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_003491903.1 6 KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807 "Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)" XP_024227646.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_003488174.1 17 MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-1622;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-561 "TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_003486393.1 4 Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" XP_012237354.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_024221068.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024228128.1 33 Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-180746 "Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"HCMV Early Events";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Nuclear import of Rev protein" XP_012236295.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012245105.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012240591.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_012248517.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_003487736.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion" XP_024225683.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_012243211.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_003494770.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012245049.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024220385.1 6 MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817 "Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis" XP_012244330.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339 "Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane" XP_012245040.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024223302.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_003489174.1 9 Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-110314 "Neddylation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recognition of DNA damage by PCNA-containing replication complex" XP_012237242.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024222674.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_012248502.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024226488.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012250062.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_024226250.1 10 Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" XP_024226232.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024227162.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012244028.1 5 MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_012246831.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_024225213.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_012248018.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012242066.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003488800.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012238508.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024227193.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012245302.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003488033.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_024226609.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_024228093.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024226172.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012247941.1 6 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Downregulation of TGF-beta receptor signaling" XP_003489550.1 56 Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling" XP_024222305.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_012246965.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012244839.1 9 KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383 "Sphingolipid metabolism";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_003491603.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012243275.2 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_003489775.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_024225974.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-211945 "PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"Xenobiotics";"Phase I - Functionalization of compounds" XP_012236876.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003494409.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012241191.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_012237483.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012242341.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003489064.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)" XP_012237969.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_024221425.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024226611.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_012249477.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003485444.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_003494340.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex" XP_012236208.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_012237960.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_012248783.2 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012249446.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012239592.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012245529.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012237372.1 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_012249921.1 1 MetaCyc: PWY-6938 "NADH repair" XP_003494764.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012245928.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012237291.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024227760.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408 "Ca2+ pathway";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation" XP_024223785.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_024226929.1 34 Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-9639288;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638 "Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Amino acids regulate mTORC1";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins" XP_003491672.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_003489049.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870 "Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins" XP_003485969.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012242055.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003484643.1 3 MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" XP_012239120.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024220927.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024223737.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012236327.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_012239215.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_012248245.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003490043.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012244924.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_003493564.1 3 MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism" XP_012247050.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_024227137.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_003489423.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024226736.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024226870.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003493288.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_012247535.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012245661.1 19 Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-5663220;Reactome: R-HSA-3928662;Reactome: R-HSA-8964616;Reactome: R-HSA-4420097;Reactome: R-HSA-389359;Reactome: R-HSA-182971;Reactome: R-HSA-5626467;Reactome: R-HSA-194840;Reactome: R-HSA-428543;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-114604;Reactome: R-HSA-525793;Reactome: R-HSA-5627123;Reactome: R-HSA-8950505 "DCC mediated attractive signaling";"RHO GTPases activate KTN1";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases Activate Formins";"EPHB-mediated forward signaling";"G beta:gamma signalling through CDC42";"VEGFA-VEGFR2 Pathway";"CD28 dependent Vav1 pathway";"EGFR downregulation";"RHO GTPases activate IQGAPs";"Rho GTPase cycle";"Inactivation of CDC42 and RAC1";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade";"Myogenesis";"RHO GTPases activate PAKs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_012245305.1 17 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-1834949;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-3270619;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Cytosolic sensors of pathogen-associated DNA";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"IRF3-mediated induction of type I IFN";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)" XP_003486212.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-6799198 "Respiratory electron transport";"Mitochondrial protein import";"Complex I biogenesis" XP_024223087.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_003490593.2 7 Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-177929 "Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR" XP_024226648.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_012237122.1 26 Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2132295 "Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"HCMV Early Events";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"MHC class II antigen presentation" XP_003493292.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024227897.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_012246851.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_003486181.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_012248958.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012240939.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_024223906.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_024223275.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012242955.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_012243724.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_012246700.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003485635.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_024222510.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_012236655.1 6 KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;MetaCyc: PWY-7356;MetaCyc: PWY-6898;MetaCyc: PWY-6907;Reactome: R-HSA-196819 "Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism" XP_003488130.1 29 Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-73863 "RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination" XP_003493357.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012239786.1 9 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)" XP_024221882.1 9 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation" XP_024221490.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003485732.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003487336.1 10 MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-7112 "Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification" XP_012239616.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003488437.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208 "Macroautophagy";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling" XP_024225495.1 3 KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857 "Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis" XP_012247100.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_012243107.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003492315.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"ATP biosynthesis";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Photosynthesis";"Ion channel transport";"Oxidative phosphorylation" XP_012247967.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024220352.1 4 Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism" XP_024228230.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024224913.1 21 MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7219;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7205 "Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism";"CMP phosphorylation" XP_003486754.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003491884.1 10 MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6901;Reactome: R-HSA-70263;KEGG: 00010+2.7.2.3 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycolysis / Gluconeogenesis" XP_024220979.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_003493522.1 5 Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921 "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation" XP_012240986.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_024225049.1 6 Reactome: R-HSA-5620916;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012239412.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024226601.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_024220398.1 7 MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363 "Phytate degradation I";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_024225500.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040 "PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation" XP_024226604.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_024226106.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024227146.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_003489481.2 14 Reactome: R-HSA-611105;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-5690;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-561 "Respiratory electron transport";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_024226217.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012244354.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012239273.1 10 MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-7344;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328 "D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis" XP_024227475.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_012247226.1 8 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection" XP_012243893.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003484726.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024221392.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_003489265.1 5 Reactome: R-HSA-901032;Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768 "ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes";"Protein ubiquitination";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_012246196.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_024228025.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_003494550.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_003494036.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003487018.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_003485020.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012241905.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012242689.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_012244246.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation" XP_024224738.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_012240722.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_024220486.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_024226259.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_024226381.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012243198.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis" XP_012242913.1 10 Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-8934903 "WNT mediated activation of DVL";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Signal transduction by L1";"Receptor Mediated Mitophagy" XP_012241445.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_003489041.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_024226528.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_003486076.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_024226200.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_003485349.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_012245506.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_012246406.1 9 Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-75955 "RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation" XP_003493249.1 4 Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation";"Propanoate metabolism" XP_012242724.1 3 Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_012244782.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024222650.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003494352.1 20 Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-176187 "HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Polymerase switching";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress" XP_012245964.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003489815.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_012244551.2 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_012243735.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72702 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition" XP_003488605.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_024225855.1 5 MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210 "CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine" XP_003492263.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244 "Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Trafficking of AMPA receptors";"RAF activation";"Long-term potentiation" XP_012238505.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_003488435.1 19 MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7226;MetaCyc: PWY-7210;Reactome: R-HSA-380320;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-6545 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of NuMA to mitotic centrosomes";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_012242430.1 11 Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196 "RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling" XP_003485326.1 5 Reactome: R-HSA-5635838;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-373080 "Activation of SMO";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Hedgehog 'off' state";"Class B/2 (Secretin family receptors)" XP_003487188.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003488699.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7417 "Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)" XP_024221281.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012244343.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024228291.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012242242.1 2 Reactome: R-HSA-2564830;Reactome: R-HSA-5693554 "Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_012241226.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_024226849.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012240467.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024224292.1 4 KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_024221243.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024225171.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012236110.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012246194.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_003486540.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012236888.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_003487154.1 32 Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-167242 "Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_024228465.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_024224393.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_024227148.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003492745.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003484405.1 4 KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines" XP_012238379.1 4 KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_024220665.1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_024227687.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_003489686.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_012241735.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_012237875.1 13 KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836;MetaCyc: PWY-7533;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6370;MetaCyc: PWY-2261;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061 "Drug metabolism - other enzymes";"Glutathione metabolism";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Ascorbate recycling (cytosolic)";"Ascorbate glutathione cycle";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I" XP_012240614.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024224079.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_003486099.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024225323.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_012245046.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003493629.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_024226194.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_003492034.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012239841.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_012242699.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024220450.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003492143.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_024226937.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_024224640.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024225499.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043 "G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events" XP_012249500.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_012245869.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-3238698 "Neutrophil degranulation";"WNT ligand biogenesis and trafficking" XP_012242101.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_024220237.1 3 MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450 "Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion" XP_003488717.1 17 Reactome: R-HSA-975163;Reactome: R-HSA-4086398;Reactome: R-HSA-445989;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-937042;Reactome: R-HSA-450321;Reactome: R-HSA-937072;Reactome: R-HSA-5689880;Reactome: R-HSA-9014325;Reactome: R-HSA-168638;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-450302 "IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ca2+ pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Ub-specific processing proteases";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"activated TAK1 mediates p38 MAPK activation" XP_003485731.2 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_012243513.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003491619.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003486567.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024223593.1 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_024223581.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012242904.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-189451 "Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis" XP_024221540.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_003493711.1 7 Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1 "Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism" XP_024224968.1 4 Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943 "Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_003491716.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_003492488.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_012248629.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_024220476.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012245006.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_024220750.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_003485198.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_012242695.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012239029.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_003490025.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012248445.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012243951.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003490843.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003494337.1 7 KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363 "Streptomycin biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_024226302.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_003485773.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_024224314.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_012240970.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins" XP_024224171.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012247418.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024226387.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_024220533.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_003492397.1 5 Reactome: R-HSA-964975;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7204;MetaCyc: PWY-7282 "Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_024225881.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892 "Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Trafficking of AMPA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation" XP_024226124.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003490112.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108 "Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis" XP_024220778.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-1368082 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"RORA activates gene expression" XP_024228490.1 6 MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_012238779.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_024221889.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_024220591.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_003487140.1 6 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2 "Cristae formation";"Mitochondrial protein import";"ATP biosynthesis";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation" XP_024224511.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003488822.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-390471;Reactome: R-HSA-983168 "Neddylation";"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012238937.1 18 Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788 "Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC" XP_024223838.1 4 Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427 "PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation";"SUMOylation of DNA methylation proteins" XP_012238022.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_024227231.1 6 Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118 "Triglyceride catabolism";"Glycerol degradation I";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle" XP_003489013.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_012245051.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012249847.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_012244560.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_012242232.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_012246548.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012244931.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_012247544.1 6 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization" XP_012249451.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_024224999.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024224972.1 4 Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943 "Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_024225582.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012243964.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_024227822.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_003491831.2 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_012249980.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion" XP_003493144.1 5 Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300 "SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA" XP_012241537.1 14 Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397 "HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_024228154.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003491147.1 11 Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-3881;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-3861 "Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II" XP_003492085.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_003488721.1 57 Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870 "ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"UCH proteinases";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins" XP_024227046.1 19 MetaCyc: PWY-5136;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7606 "Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)" XP_012249329.1 5 Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88 "Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism" XP_024225537.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_024221536.1 7 Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838 "Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Activation of SMO" XP_024226678.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_012249380.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_003487709.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_024226743.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_024223515.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024225454.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024222868.1 8 Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-111464 "TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Regulation of the apoptosome activity";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_003484976.1 8 Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69091 "Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"DNA replication initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching" XP_003493117.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-1799339 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane" XP_012242195.1 8 Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-190873 "EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"Gap junction degradation" XP_003487767.3 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024221090.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012245038.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012248244.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012237829.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_012239668.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003486583.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_024227474.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_012244172.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_024225885.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948 "Long-term potentiation";"RAF activation";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants" XP_024227380.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012244811.1 9 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection" XP_003493686.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_003489631.1 56 Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590 "TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling" XP_003485810.1 9 Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"Neddylation";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_024220797.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_012250245.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_012248847.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_012236437.1 3 MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_003492541.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012245833.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_012238070.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport" XP_003493156.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_012246929.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012240089.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_003491915.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012244693.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events" XP_003485848.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163615 "Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"PKA activation" XP_003485458.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003489091.2 6 Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-110357;Reactome: R-HSA-110362 "Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair" XP_012248641.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_024224441.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012238025.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_012240280.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_012243950.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_024220718.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003492332.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001 "NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade" XP_003485605.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_003486267.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_012243325.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_024226148.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012239460.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024220564.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003492853.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003487683.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024226352.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024226348.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012243201.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012246062.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024226589.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003492839.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_012243080.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024223553.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012248182.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012248072.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_012245200.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_012244563.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012241333.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003488499.1 17 Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-5358565 "Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_003484390.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012242590.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012247920.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024226761.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_024228480.1 13 MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;MetaCyc: PWY-6367;Reactome: R-HSA-202433;Reactome: R-HSA-9027277;Reactome: R-HSA-2871796;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"DAP12 signaling";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"D-myo-inositol-5-phosphate metabolism";"Generation of second messenger molecules";"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated MAPK activation";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis" XP_003488587.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024222422.1 8 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_012237053.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_024222716.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_003491925.1 3 KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_012248778.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_012239809.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-8951664;Reactome: R-HSA-349425 "Protein ubiquitination";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1" XP_024228369.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_012245202.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_012237803.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_003489429.1 11 Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685942 "Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)" XP_003489169.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_024227754.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003492071.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003493545.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012236139.2 4 Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_012247899.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_024220749.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_012238941.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012249796.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024226329.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012237962.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_003485533.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_003487362.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003493491.2 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_003491270.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_003491458.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_012236547.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012249390.2 15 MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7218 "Rubisco shunt";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_003492545.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012236535.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003490267.1 4 Reactome: R-HSA-6811440;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Retrograde transport at the Trans-Golgi-Network";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024225661.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_024224937.1 10 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription" XP_012246823.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012240329.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012248719.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_024223808.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_003488382.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003487066.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_024226064.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012246041.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024220552.1 6 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-416993;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Trafficking of GluR2-containing AMPA receptors";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003485610.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012242233.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_024220981.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_003486201.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_012239742.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_012249007.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590 "Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation" XP_012237440.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_012237472.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_003487022.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003485806.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_012238042.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024228078.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine" XP_003490493.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012237318.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_024226487.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003487958.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897 "Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Macroautophagy";"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes" XP_012237692.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012237093.2 26 Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436 "Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Mitotic Prometaphase";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic" XP_012239084.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate" XP_012243057.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_012245819.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_012236462.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024226738.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_024224525.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_003490218.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_012249913.1 3 KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_024223755.1 6 Reactome: R-HSA-5684045;Reactome: R-HSA-2046105;Reactome: R-HSA-2046106;Reactome: R-HSA-390247;Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Linoleic acid (LA) metabolism";"alpha-linolenic acid (ALA) metabolism";"Beta-oxidation of very long chain fatty acids";"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_012238482.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159231 "snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_024222509.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_024227183.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_024224093.1 4 MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163 "Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism" XP_024223904.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_003489149.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism" XP_003493997.2 14 KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-975634;Reactome: R-HSA-1482788 "Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Acyl chain remodelling of PC" XP_003492002.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" XP_012249381.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-5633231 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_024227673.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_003491300.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003489564.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012248160.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_003492454.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_012239602.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_003488816.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012246715.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_012236898.1 12 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-5250924;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression" XP_012241251.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_003485152.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_003490051.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012240625.1 5 Reactome: R-HSA-381038;Reactome: R-HSA-901032;MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768 "XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)";"Protein ubiquitination";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_024223812.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012250441.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" XP_012239146.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_012249365.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_003487371.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012237961.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_012236436.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol" XP_024224777.1 5 MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-6782861;Reactome: R-HSA-196843 "Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Vitamin B2 (riboflavin) metabolism" XP_003490958.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_003484724.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_012249296.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_012250262.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_012237332.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012249789.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003493980.1 7 Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201 "Mitochondrial protein import";"ATP biosynthesis";"Cristae formation";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_012237967.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_024225084.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_012242406.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_024225057.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012245264.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736 "Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Trafficking of AMPA receptors";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors" XP_024226454.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024223095.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024227006.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_024226443.1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" XP_003488892.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_024225608.1 7 Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628 "Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_012248149.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012248775.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_024220934.1 3 Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-933542 "TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation" XP_024224220.1 17 Reactome: R-HSA-176187;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6796648;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;KEGG: 04714+2.7.11.1 "Activation of ATR in response to replication stress";"Human immunodeficiency virus 1 infection";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"Human papillomavirus infection";"mTOR signaling pathway";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Thermogenesis" XP_012250372.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012244021.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003488088.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-5466 "Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Matairesinol biosynthesis" XP_012245922.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_003487820.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012244417.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024226252.1 10 KEGG: 00410+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6537;Reactome: R-HSA-916853;MetaCyc: PWY-6535;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-5022;KEGG: 00650+2.6.1.19 "beta-Alanine metabolism";"L-glutamate degradation IV";"Propanoate metabolism";"4-aminobutanoate degradation II";"Degradation of GABA";"4-aminobutanoate degradation I";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation III";"4-aminobutanoate degradation V";"Butanoate metabolism" XP_024225772.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis" XP_012242923.1 7 Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-264870;Reactome: R-HSA-373753 "RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions" XP_024222340.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553 "mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs" XP_012243886.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_024227344.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012239226.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012246936.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012246160.1 12 MetaCyc: PWY-3801;MetaCyc: PWY-7817;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599 "Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Glycerolipid metabolism";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate" XP_003487841.2 56 Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-202424 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"UCH proteinases";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling" XP_003492847.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_024227005.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_024220712.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473 "Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint" XP_012247854.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_024228094.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012243738.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_012250476.1 3 Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757 "HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation" XP_003489323.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003494225.1 33 Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885 "Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"SUMOylation of DNA replication proteins" XP_012247885.1 16 Reactome: R-HSA-9009391;Reactome: R-HSA-114604;Reactome: R-HSA-512988;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-389357;Reactome: R-HSA-6811558;Reactome: R-HSA-1433557;Reactome: R-HSA-912526;Reactome: R-HSA-912631;Reactome: R-HSA-1660499;Reactome: R-HSA-388841;Reactome: R-HSA-194840;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-1266695 "Extra-nuclear estrogen signaling";"GPVI-mediated activation cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"CD28 dependent PI3K/Akt signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by SCF-KIT";"Interleukin receptor SHC signaling";"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane";"Costimulation by the CD28 family";"Rho GTPase cycle";"RET signaling";"G alpha (q) signalling events";"Interleukin-7 signaling" XP_012248722.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012241336.1 7 KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;MetaCyc: PWY-5129;MetaCyc: PWY-7838;MetaCyc: PWY-7836;MetaCyc: PWY-7839;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism" XP_003488441.1 5 KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863;MetaCyc: PWY-6168;Reactome: R-HSA-196843;MetaCyc: PWY-5523 "Riboflavin metabolism";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)" XP_024227328.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024226788.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_024220263.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_024221421.1 11 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8866654;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Human papillomavirus infection" XP_012238800.1 5 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-201722 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex" XP_024220241.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_024221650.1 8 Reactome: R-HSA-6787639;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5739;MetaCyc: PWY-66;MetaCyc: PWY-7573 "GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-D-perosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis" XP_024228192.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024224162.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_012241967.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012239497.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_003489284.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232 "Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_024228020.1 12 MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;KEGG: 00450+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4 "Sulfate activation for sulfonation";"Sulfur metabolism";"Sulfur metabolism";"Selenocompound metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Monobactam biosynthesis";"Sulfite oxidation III";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Assimilatory sulfate reduction III";"Purine metabolism" XP_012249758.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_003493044.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003490672.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012239102.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_024226813.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024224667.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_012241619.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_024228290.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_003493372.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024225714.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_012237691.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012249479.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003486265.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_012242696.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024223513.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_024225232.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642 "Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_003494899.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024222061.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_012248771.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_003489506.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024220515.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003489580.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_024221694.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_003490123.1 7 Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-212436;Reactome: R-HSA-2122947 "Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Generic Transcription Pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_012242862.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024225189.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642 "Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle" XP_012244283.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_003493653.1 10 KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2 "Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism" XP_024222282.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012237985.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012245300.1 9 KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822 "Other glycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)" XP_024225782.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_024221930.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214 "Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs" XP_024220596.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_012245553.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_003491647.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012241193.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_024225652.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012240928.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_012248020.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003490330.1 22 MetaCyc: PWY-5659;Reactome: R-HSA-5628897;MetaCyc: PWY-6142;MetaCyc: PWY-6981;Reactome: R-HSA-70171;MetaCyc: PWY-622;MetaCyc: PWY-3801;KEGG: 00500+5.3.1.9;MetaCyc: PWY-8013;KEGG: 00520+5.3.1.9;MetaCyc: PWY-5384;MetaCyc: PWY-7385;Reactome: R-HSA-70263;MetaCyc: PWY-7238;KEGG: 00010+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-621;KEGG: 00030+5.3.1.9;MetaCyc: PWY-5054;MetaCyc: PWY-5514;Reactome: R-HSA-6798695;MetaCyc: PWY-6992 "GDP-mannose biosynthesis";"TP53 Regulates Metabolic Genes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Chitin biosynthesis";"Glycolysis";"Starch biosynthesis";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation IV (sucrose phosphorylase)";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Sucrose biosynthesis II";"Glycolysis / Gluconeogenesis";"Sucrose biosynthesis III";"Sucrose degradation III (sucrose invertase)";"Pentose phosphate pathway";"D-sorbitol biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Neutrophil degranulation";"1,5-anhydrofructose degradation" XP_012248491.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012244914.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_012238329.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion" XP_012244523.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_003488713.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_012237588.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024220861.1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis" XP_024227135.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_024225288.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012237587.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_012237398.1 7 Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-5685939;Reactome: R-HSA-3108214;Reactome: R-HSA-2173795;Reactome: R-HSA-5696394 "Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER" XP_012243401.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_024228314.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_012236432.1 5 MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263 "Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Gluconeogenesis" XP_012249498.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins" XP_024227870.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_003491888.1 9 KEGG: 00401+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00950+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5 "Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis" XP_024225698.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_012243161.1 13 KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902 "Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Chitin degradation II (Vibrio)" XP_012241850.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012242698.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024224563.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_024223742.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_012246849.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_012237474.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_012237987.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003494138.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024220468.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003492639.1 6 Reactome: R-HSA-3371599;MetaCyc: PWY-6987;Reactome: R-HSA-196780;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181 "Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Lipoic acid metabolism" XP_012244698.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport" XP_003486495.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation" XP_024222613.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_012240771.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024224971.1 4 Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221 "Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis" XP_012246066.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" XP_024221543.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_012242379.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_012241203.2 6 MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1;KEGG: 00030+5.1.3.1 "Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" XP_024224253.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_012237964.2 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_012247225.1 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis" XP_012249241.1 56 Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783 "Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"UCH proteinases";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI2 by the proteasome" XP_024225508.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012244729.1 11 Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-75955 "Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation" XP_003493896.3 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012236752.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_012239095.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_012244710.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_012246034.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012239487.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012242705.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024221666.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_024221137.1 6 MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_012243266.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_012247323.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012245598.1 15 Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-3769402;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5689896 "APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases" XP_003489282.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012237313.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_003493287.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_012241949.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012244773.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_024221956.1 18 Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166 "Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Synthesis of PA" XP_012245919.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_024224438.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003490814.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_024227886.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_012250103.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012242381.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003489148.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-191859 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"snRNP Assembly" XP_012239153.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_003486123.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_012242702.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003487865.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012242723.1 3 MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_012249311.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681 "G alpha (i) signalling events";"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT" XP_003494645.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_012243929.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012246733.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_012237444.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_003486642.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6807505 "RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes" XP_012246260.1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" XP_012247696.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003485155.1 10 Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-917729;Reactome: R-HSA-182971;Reactome: R-HSA-432720;Reactome: R-HSA-8856825 "Ub-specific processing proteases";"Inhibition of membrane repair";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"EGFR downregulation";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis" XP_012245805.1 6 MetaCyc: PWY-6987;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15 "Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism" XP_012245832.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_003488818.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_012249642.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024224386.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_012237957.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_024225640.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012243424.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_012238936.1 18 MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4 "Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Synthesis of PA";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism" XP_003487508.1 58 Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-5689901;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870 "ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Metalloprotease DUBs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins" XP_012243561.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024220242.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_024224012.1 7 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation" XP_024225534.1 13 Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-419037;Reactome: R-HSA-2022090;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-2214320;Reactome: R-HSA-3000178;Reactome: R-HSA-1442490 "Laminin interactions";"Collagen chain trimerization";"Signaling by PDGF";"Integrin cell surface interactions";"NCAM1 interactions";"Assembly of collagen fibrils and other multimeric structures";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Anchoring fibril formation";"ECM proteoglycans";"Collagen degradation" XP_003484875.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012239990.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_003485122.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_024220478.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003493651.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012243570.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012248219.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_024222379.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003493516.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024228099.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024222331.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_024222031.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_003491360.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_003485277.1 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" XP_024221250.1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" XP_012239410.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_024227306.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_024223816.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_012239893.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012237203.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024226008.1 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)" XP_012244182.1 14 KEGG: 00280+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5076;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00270+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5108;MetaCyc: PWY-5103;MetaCyc: PWY-5101;MetaCyc: PWY-5057;KEGG: 00770+2.6.1.42;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis IV";"L-leucine degradation III";"Glucosinolate biosynthesis";"L-isoleucine degradation II";"Cysteine and methionine metabolism";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis II";"L-valine degradation II";"Pantothenate and CoA biosynthesis";"Branched-chain amino acid catabolism" XP_003484396.1 29 Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-69541;Reactome: R-HSA-912446;KEGG: 05163+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-5693571;Reactome: R-HSA-6803207;Reactome: R-HSA-6804756;Reactome: R-HSA-6804760;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5685942;Reactome: R-HSA-6803204;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;KEGG: 05165+2.7.11.1 "DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Human immunodeficiency virus 1 infection";"Regulation of HSF1-mediated heat shock response";"Stabilization of p53";"Meiotic recombination";"Human cytomegalovirus infection";"Autodegradation of the E3 ubiquitin ligase COP1";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Activity through Methylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"mTOR signaling pathway";"Thermogenesis";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Human papillomavirus infection" XP_024227359.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024223924.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012243293.1 3 KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors" XP_024220454.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003494366.2 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_024223273.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003485724.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_024221286.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024227930.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_024221244.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012243425.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_024225643.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012244594.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_012245318.1 31 MetaCyc: PWY-5973;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWYG-321;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;Reactome: R-HSA-75105;MetaCyc: PWY-6799;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-7664;MetaCyc: PWY-5994;MetaCyc: PWY-5142;MetaCyc: PWY-5989;MetaCyc: PWY-6519;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8047;MetaCyc: PWY-7858;MetaCyc: PWY-5367;MetaCyc: PWY-7388;MetaCyc: PWY-7746;MetaCyc: PWY-4381;MetaCyc: PWY-6282;MetaCyc: PWY-6113;MetaCyc: PWY-8012;MetaCyc: PWY-7723;MetaCyc: PWY-5147;MetaCyc: PWY-5971;MetaCyc: PWY-8049 "Cis-vaccenate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Bryostatin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Petroselinate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"Mupirocin biosynthesis";"Bacterial bioluminescence";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Pederin biosynthesis" XP_012240871.1 15 Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-3769402;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333 "Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Deactivation of the beta-catenin transactivating complex";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated" XP_024225452.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024227535.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024227607.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012239485.1 4 MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"Selenocompound metabolism" XP_024227014.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_003489930.1 13 KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;Reactome: R-HSA-3928663;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"EPHA-mediated growth cone collapse";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection" XP_012244441.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_003485745.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_024220627.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_012237060.1 4 MetaCyc: PWY-7383;MetaCyc: PWY-8040;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1 "Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"Alanine racemization";"D-Alanine metabolism" XP_003489260.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024221218.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024227320.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_024221509.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_003492856.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_003491346.2 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_024223492.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_024226607.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012239532.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_003491891.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-1660499 "Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane" XP_012238021.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_012241071.1 4 Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_024226700.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_024222669.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012239399.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_012243565.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012246906.1 7 KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00710+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00030+3.1.3.11 "Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Pentose phosphate pathway" XP_003485440.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_003490724.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" XP_024226949.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012249408.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012237564.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_024225783.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003488140.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_024226407.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_024221818.1 17 Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-174414;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801 "Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Processive synthesis on the C-strand of the telomere";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair" XP_012241546.2 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_012247079.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024227925.1 42 MetaCyc: PWY-6863;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5789;MetaCyc: PWY-5136;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-6945;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-7216;MetaCyc: PWY-6944;MetaCyc: PWY-7656;MetaCyc: PWY-7401;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7007;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00623+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7779;MetaCyc: PWY-6583;MetaCyc: PWY-7778;MetaCyc: PWY-1361;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00280+4.2.1.17+1.1.1.35 "Pyruvate fermentation to hexanol (engineered)";"beta-Alanine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid beta-oxidation II (plant peroxisome)";"Tryptophan metabolism";"Glutaryl-coa degradation";"Fatty acid degradation";"Butanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"Geraniol degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Limonene and pinene degradation";"Pyruvate fermentation to butanol II (engineered)";"Aminobenzoate degradation";"4-hydroxybenzoate biosynthesis III (plants)";"alpha-Linolenic acid metabolism";"Fatty acid salvage";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Androstenedione degradation";"Spodoptera littoralis pheromone biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Butanoate metabolism";"Caprolactam degradation";"Fermentation to 2-methylbutanoate";"Methyl ketone biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Fatty acid elongation";"Phenylalanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Toluene degradation";"Benzoate degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to butanol I";"2-methylpropene degradation";"Benzoyl-coa degradation I (aerobic)";"Lysine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Valine, leucine and isoleucine degradation" XP_003486559.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003486082.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003492482.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_012236966.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_012247406.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024228103.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003493481.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012240845.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_024220479.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012238000.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_012237319.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_024226036.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003494040.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_003491181.1 6 KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)" XP_003491253.1 16 Reactome: R-HSA-8951664;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167287;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167200 "Neddylation";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_012242852.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012237202.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003492647.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_003493907.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_012242674.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012240245.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012243145.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_024224436.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_012244856.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024222258.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_003493846.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012247408.1 3 Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11 "Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" XP_024221867.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003485784.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_003489694.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024221282.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003488203.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_012237817.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012236975.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003484720.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-432040 "Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Purine metabolism";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_024225724.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012240357.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-191859;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "RORA activates gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"snRNP Assembly";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_024224152.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_012238262.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_024225233.1 13 Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-437239;Reactome: R-HSA-177504 "MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Recycling pathway of L1";"Retrograde neurotrophin signalling" XP_024222033.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_012247798.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_003492262.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955 "RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Long-term potentiation";"RAF activation";"Ion homeostasis";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_024228197.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012237054.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012238704.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_003493877.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_024225327.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_003488571.1 2 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_003492836.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003489552.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012245207.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_003486733.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_012241948.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024220455.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012239545.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_024225854.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_003491296.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_012250234.1 14 MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-1187;Reactome: R-HSA-8964208;MetaCyc: PWY-601;MetaCyc: PWY-801;Reactome: R-HSA-71240;MetaCyc: PWY-6936;Reactome: R-HSA-8964539;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7 "L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Phenylalanine metabolism";"Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"Glutamate and glutamine metabolism";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism" XP_012238150.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_024227802.1 3 Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" XP_003488586.2 5 Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379 "Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events" XP_024222670.1 7 Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034 "Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Activation of SMO";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np" XP_003488289.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway" XP_012243227.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization" XP_012246530.1 12 Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1839117 "NRAGE signals death through JNK";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Rho GTPase cycle";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Signaling by FGFR1 in disease";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"Signaling by cytosolic FGFR1 fusion mutants" XP_003488110.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-168138 "Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade" XP_012237590.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024222851.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_012249278.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_003486985.1 6 KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952 "Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_012249733.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-432040 "Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"PKA activation in glucagon signalling";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_012241567.1 10 Reactome: R-HSA-201722;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Formation of the beta-catenin:TCF transactivating complex";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Ub-specific processing proteases";"HATs acetylate histones";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_003494328.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_024223679.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003487888.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024221434.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003486581.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024224434.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012239469.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_024222701.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_024227587.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_012246611.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_003493693.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012245927.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_024224225.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003492243.1 4 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270 "Glycerol degradation I";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate" XP_024228430.1 11 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;Reactome: R-HSA-4420097 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"VEGFA-VEGFR2 Pathway" XP_003484539.1 14 KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7783;MetaCyc: PWY-7409 "Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_024226814.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_003486200.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012242148.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_024223560.1 33 Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"HCMV Early Events";"RHO GTPases Activate Formins" XP_024224657.1 8 Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001 "Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade" XP_012237798.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_012238820.1 11 MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8052 "Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Role of phospholipids in phagocytosis";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis" XP_024221310.1 24 Reactome: R-HSA-202424;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-389357;Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;Reactome: R-HSA-5607764;KEGG: 05163+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-6804757;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218921;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1 "Downstream TCR signaling";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"Activation of AKT2";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"CLEC7A (Dectin-1) signaling";"Human cytomegalovirus infection";"Integrin signaling";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of TP53 Degradation";"RSK activation";"PI3K-Akt signaling pathway";"RHO GTPases activate PKNs";"Human papillomavirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated cell proliferation";"VEGFR2 mediated vascular permeability";"Thermogenesis" XP_024220492.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003488566.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012242231.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012248709.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_012248919.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation" XP_024225631.1 7 MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753 "UMP biosynthesis II";"Drug metabolism - other enzymes";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine biosynthesis" XP_024228237.1 12 Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-429947 "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA" XP_012236313.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003492760.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_024227430.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_024223968.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_024220461.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012243932.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003490459.1 3 KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350 "Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism" XP_012244127.1 7 Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790 "Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis II" XP_024222512.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024224655.1 12 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-438066 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation" XP_003486983.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_024227436.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024227656.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_024228075.1 3 Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638 "RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_003486636.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-1660661;Reactome: R-HSA-9609523 "Neutrophil degranulation";"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012243031.1 27 Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-159230 "NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA" XP_024223969.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_003488103.2 5 MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-7176 "UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis" XP_012249842.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_024224359.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_012240633.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012244676.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_003485630.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_012250058.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs" XP_012249373.1 4 Reactome: R-HSA-8866427;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-9031525 "VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake" XP_012244243.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_012248224.2 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012237223.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012242265.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_024225678.1 8 MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273 "Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis" XP_003486746.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_003488833.1 18 MetaCyc: PWY-7511;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5689901;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-6796648 "Protein ubiquitination";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Metalloprotease DUBs";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of DNA Repair Genes" XP_012237986.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_024224336.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012238189.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_003485301.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012248956.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012245956.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012245764.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012239946.1 11 Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948 "Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_012238791.1 7 KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_012249464.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012249911.1 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_024223368.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade" XP_024226903.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003488363.1 2 Reactome: R-HSA-73621;Reactome: R-HSA-500753 "Pyrimidine catabolism";"Pyrimidine biosynthesis" XP_024228036.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_024221656.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_024228153.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012249227.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_012243291.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_012245080.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_012247316.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_012237323.1 24 Reactome: R-HSA-392451;Reactome: R-HSA-9634635;Reactome: R-HSA-354192;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-2871837;Reactome: R-HSA-165158;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-202424;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-5218921;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905 "G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"Integrin signaling";"Human cytomegalovirus infection";"CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation";"Activation of AKT2";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"Downstream TCR signaling";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated cell proliferation";"mTOR signaling pathway";"Human papillomavirus infection";"RHO GTPases activate PKNs";"PI3K-Akt signaling pathway";"RSK activation";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization" XP_012238024.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_024221462.1 9 KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism" XP_012243861.1 8 Reactome: R-HSA-8953750;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_012236836.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_003488734.1 11 MetaCyc: PWY-7821;MetaCyc: PWY-6608;MetaCyc: PWY-6596;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6606;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-5381 "Tunicamycin biosynthesis";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)" XP_024223931.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_003492395.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_003492721.1 8 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human papillomavirus infection" XP_012245994.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003486597.2 8 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-7817;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;KEGG: 05235+3.1.3.16;MetaCyc: PWY-5269 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Synthesis of PG";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Cardiolipin biosynthesis II" XP_003491507.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_024221272.1 24 Reactome: R-HSA-392451;Reactome: R-HSA-428930;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-420092 "G beta:gamma signalling through PI3Kgamma";"Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"G-protein activation";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors" XP_012250475.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_003487946.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003490977.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972 "Sciadonate biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)" XP_012242865.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_003488083.1 3 Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282 "HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B" XP_003485146.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_003492172.2 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012249925.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial protein import";"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012241847.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003494894.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024220463.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024224437.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6807505;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination" XP_024223293.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_003491553.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012236424.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_012248626.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_024220549.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_012245586.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003488718.1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-983231 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production" XP_024221071.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024222502.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "ECM proteoglycans";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_012244042.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012249576.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012243430.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024227537.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" XP_003487599.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_012239707.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_024227254.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_012236549.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024226080.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012244193.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_012237595.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72702 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition" XP_024221600.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-5673001 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K Cascade";"RAF/MAP kinase cascade" XP_024224592.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_003487039.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024226587.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024227766.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012243171.1 12 MetaCyc: PWY-7221;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-451308 "Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor" XP_003486343.1 8 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418889 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Caspase activation via Dependence Receptors in the absence of ligand" XP_003488564.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_024225205.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-388844 "Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_024220495.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024224067.1 4 Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10 "Selenoamino acid metabolism";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_024225036.1 4 Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722 "Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)" XP_012239403.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_012242420.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_012238909.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024223291.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_012240305.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_012247295.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012244746.1 10 MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00051+5.3.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+5.3.1.1;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263 "Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Gluconeogenesis" XP_012246344.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003490404.1 4 KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_003494788.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_024227299.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_024226280.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012250320.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_012236632.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_012241192.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_024228332.1 20 MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338 "6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)" XP_003489014.2 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_024224175.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003488839.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003485993.1 5 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis" XP_003491508.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_012250028.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024224654.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244 "Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation" XP_012237996.1 5 Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_003486680.1 4 Reactome: R-HSA-164944;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-8849471 "Nef and signal transduction";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_003485050.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_012239168.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012246972.1 3 Reactome: R-HSA-196741;Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism" XP_024225450.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012250041.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003490125.1 29 Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-5696400;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-6781827 "RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_003492341.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_024222246.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_012236613.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling" XP_024223562.1 33 Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-180910 "Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs" XP_012244925.1 5 Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695 "Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Neutrophil degranulation" XP_024220803.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024224306.1 26 Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-201722;Reactome: R-HSA-8866907;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-3899300;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-3371568 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"RORA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Activation of the TFAP2 (AP-2) family of transcription factors";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"SUMOylation of transcription cofactors";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Attenuation phase" XP_024228287.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_024226805.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012236495.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_024223277.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_003489572.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_024220598.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_024224690.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012246697.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003487144.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012249701.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_024220802.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003488781.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_012247317.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024222848.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268 "Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_024226962.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_012238155.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex" XP_024220235.1 7 Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-5368598;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-4641258;Reactome: R-HSA-201681 "WNT mediated activation of DVL";"PCP/CE pathway";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of DVL";"TCF dependent signaling in response to WNT" XP_012240525.1 4 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;Reactome: R-HSA-2408557 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis" XP_003488310.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation" XP_003490639.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003489766.2 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_012244450.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-388844 "Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_003488951.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024222571.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024223572.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024225545.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_024222672.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012248924.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress" XP_003491795.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012237420.1 4 Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255 "HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis" XP_003486141.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6 "Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_024223044.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_024225242.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_024224889.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4086398 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway" XP_012246564.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-5689880 "Macroautophagy";"Ub-specific processing proteases" XP_003488530.1 8 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_012237412.1 4 Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437 "HATs acetylate histones";"UCH proteinases";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation" XP_012241104.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_012237862.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024227293.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_024226101.1 5 MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880 "Protein ubiquitination";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases" XP_012241742.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_003491709.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_003490147.1 10 Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-3299685;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-5628897 "SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes" XP_003489871.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003488996.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003490527.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_012243006.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024220559.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012248449.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024222090.1 7 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22 "Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism" XP_012249897.1 30 Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-5696400;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-2564830;Reactome: R-HSA-167246;Reactome: R-HSA-112382 "Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual Incision in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Cytosolic iron-sulfur cluster assembly";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex" XP_003490602.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003491380.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_012249844.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024224675.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012244211.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_024222377.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_024224660.1 8 Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324 "Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_012242270.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-70171;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514 "Chitin degradation I (archaea)";"Glycolysis";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_024222470.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_024221028.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_012236277.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_024228165.1 2 Reactome: R-HSA-5633231;Reactome: R-HSA-446193 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_012238433.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_003494917.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012248991.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012247637.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012248703.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_024222335.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_012245199.1 6 MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_012241653.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_003484431.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane" XP_024222337.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_024220813.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012244327.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024228155.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012248957.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_012237146.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_024220977.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_024227455.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_012242512.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_012243213.1 6 KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism" XP_012247903.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_024227695.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_024228073.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_012249012.1 22 Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"RAF activation";"RHO GTPases Activate Formins" XP_012244237.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation" XP_024227481.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_024227033.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695 "Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Neutrophil degranulation" XP_003492114.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024226442.1 6 KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-5530;MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17 "Caprolactam degradation";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism" XP_024224021.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170 "MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_024221165.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_024226676.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_003493613.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_012244960.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_012248086.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012238426.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012243756.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_024228110.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003488874.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_003485167.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"Kinesins" XP_024222052.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_003488370.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs" XP_024227377.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-5685938;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint" XP_003494521.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768 "ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"UCH proteinases";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_012242946.1 8 Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823 "Ub-specific processing proteases";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex" XP_012241335.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003487253.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024224050.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012236510.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012245840.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012243959.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_024226085.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_003485928.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024227585.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003491183.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_003489308.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003490927.1 4 Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483;MetaCyc: PWY-5874 "Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation";"Heme degradation I" XP_012236541.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012244907.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012244912.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_003494115.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003485692.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_003485752.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_003488510.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_003487323.1 9 MetaCyc: PWY-6367;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system" XP_012238566.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_003485519.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_024226958.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_003494771.3 5 Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344 "Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)" XP_024221026.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_024221515.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003491484.2 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_012239840.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_024226789.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_012249508.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_024226171.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012246848.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_003486130.1 18 MetaCyc: PWY-6643;MetaCyc: PWY-7117;MetaCyc: PWY-6642;KEGG: 00401+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00360+2.6.1.1;KEGG: 00270+2.6.1.1 "Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Novobiocin biosynthesis";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Sulfolactate degradation III";"Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Carbon fixation in photosynthetic organisms";"Alanine, aspartate and glutamate metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Phenylalanine metabolism";"Cysteine and methionine metabolism" XP_012242847.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003484516.1 14 MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433 "Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_003487609.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_024227388.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024228201.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5080 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_003489537.1 11 Reactome: R-HSA-210990;Reactome: R-HSA-9008059;Reactome: R-HSA-114604;Reactome: R-HSA-877312;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-391160;Reactome: R-HSA-389948;Reactome: R-HSA-432142;Reactome: R-HSA-912694;Reactome: R-HSA-388841 "PECAM1 interactions";"Interleukin-37 signaling";"GPVI-mediated activation cascade";"Regulation of IFNG signaling";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Signal regulatory protein family interactions";"PD-1 signaling";"Platelet sensitization by LDL";"Regulation of IFNA signaling";"Costimulation by the CD28 family" XP_012239385.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_012247384.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_024227557.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003491964.1 40 Reactome: R-HSA-5617472;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-203927;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-167238 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"MicroRNA (miRNA) biogenesis";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation" XP_024224123.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_003487331.2 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012250237.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_024226959.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_024226133.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012242924.1 7 Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-373753 "Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Nephrin family interactions" XP_024221138.1 6 MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363 "D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_003487034.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_024222054.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_024224160.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003487373.1 8 KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1 "Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis" XP_003488606.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012242592.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012239353.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670 "Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway" XP_003492211.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_012244521.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_003488960.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_024223356.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003484407.1 4 MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726 "Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation" XP_003491138.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024227525.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_024223046.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012244855.1 9 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_012241560.1 10 Reactome: R-HSA-5689880;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1 "Ub-specific processing proteases";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"HATs acetylate histones";"Thermogenesis" XP_012238522.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012247044.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740 "Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs" XP_003489171.1 13 MetaCyc: PWY-2201;MetaCyc: PWY-6613;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;Reactome: R-HSA-196757;MetaCyc: PWY-1722 "Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"One carbon pool by folate";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate" XP_024221814.1 15 Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-9603505;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-112382 "Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"NTRK3 as a dependence receptor";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex" XP_024223627.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024226260.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_012249225.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012250081.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003494922.1 6 MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5789;Reactome: R-HSA-196780 "3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism" XP_012247416.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024225287.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003484448.1 9 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_012244731.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003490658.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003490230.1 7 Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310 "G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway" XP_024221088.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024225642.1 5 MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;MetaCyc: PWY-5686;MetaCyc: PWY-7791;Reactome: R-HSA-500753 "UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine biosynthesis" XP_012239150.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_003484954.1 56 Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541 "APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway" XP_024225159.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_024221437.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024225945.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_003485618.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024226123.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_024226952.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012242154.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_024227298.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_012243625.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_024225004.1 10 MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2 "Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism" XP_003485952.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_024228487.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_012244978.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_012247906.1 4 Reactome: R-HSA-901032;KEGG: 00513+3.2.1.113;KEGG: 00510+3.2.1.113;MetaCyc: PWY-7919 "ER Quality Control Compartment (ERQC)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)" XP_012247493.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_003492093.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_003489805.1 14 Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-5651801 "Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair" XP_024228455.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis" XP_012236886.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_012242293.1 5 Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857 "MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"Keratan sulfate degradation" XP_003484784.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_012247321.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_003485911.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003488556.1 3 Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "Glycine degradation";"One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_012250014.1 13 MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871796;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-202433;Reactome: R-HSA-9027277;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;MetaCyc: PWY-7039 "2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"FCERI mediated MAPK activation";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Generation of second messenger molecules";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidylinositol signaling system";"DAP12 signaling";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule" XP_012250251.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024224778.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003485366.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003484961.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_024226644.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_024228108.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012250336.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003489955.2 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012243878.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_003493051.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination" XP_012240189.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012247756.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_012242505.1 4 MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_003487482.1 6 MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21 "Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_024226128.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024222816.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_012249489.1 6 Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_003486522.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003490783.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_012246983.1 7 KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134 "Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Phenylalanine metabolism";"Phenylketonuria";"Folate biosynthesis";"L-tyrosine biosynthesis IV" XP_012240422.2 6 Reactome: R-HSA-6781823;Reactome: R-HSA-6798695;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210 "Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_012242126.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_012246566.2 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_012243241.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_012249312.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681 "G alpha (i) signalling events";"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT" XP_024224786.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003490947.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs" XP_024225378.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-2160916 "AURKA Activation by TPX2";"Hyaluronan uptake and degradation" XP_012243072.1 5 Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation" XP_003494141.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_012236631.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_012246691.1 4 Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16 "Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_024225191.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-264642 "Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_024221089.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024226691.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012245179.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012239763.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_003488746.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012237118.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"AURKA Activation by TPX2" XP_012236877.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024221921.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_012241986.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012243740.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_024228130.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_003490251.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_012245174.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003486691.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024222383.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_012236629.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_003489047.1 17 MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;Reactome: R-HSA-74217;MetaCyc: PWY-5695;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-7179;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-6644;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1 "Guanine and guanosine salvage";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation I";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Purine metabolism" XP_003492426.1 2 KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105 "Fatty acid elongation";"Fatty acyl-CoA biosynthesis" XP_012238380.1 4 KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012244564.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_024227732.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024221229.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012241635.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_024223079.1 13 Reactome: R-HSA-196757;MetaCyc: PWY-1722;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2161;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-6613 "Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Folate polyglutamylation";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_003489309.1 3 Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166 "Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2" XP_024227869.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003492904.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs" XP_012239915.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_024223272.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012238481.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-168333 "Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_012249740.2 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_024226658.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_003490733.1 6 Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_003486247.1 4 Reactome: R-HSA-1237112;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_012245610.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012247006.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024220554.1 3 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes" XP_012249646.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012238923.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_024221735.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_003487355.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_024224331.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_012249306.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_024220929.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012243309.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_012239155.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_024223447.1 9 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_024227042.1 9 Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946 "Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants" XP_024226767.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_024220624.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024222098.1 11 Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-8940973 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation" XP_012240282.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_024223063.1 5 Reactome: R-HSA-5620924;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-983189 "Intraflagellar transport";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins" XP_024224161.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012237288.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012244791.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_012243327.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012249352.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_012249513.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_012240778.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012239005.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_003494106.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14 "Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012249531.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_024226852.1 6 MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_003485753.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events" XP_012239617.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012245167.1 18 KEGG: 00680+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-8086;MetaCyc: PWY-1622;MetaCyc: PWY-561;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;Reactome: R-HSA-70263;KEGG: 00270+1.1.1.37 "Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis";"Cysteine and methionine metabolism" XP_012246833.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_012243870.1 19 Reactome: R-HSA-983231;Reactome: R-HSA-114604;Reactome: R-HSA-5627123;Reactome: R-HSA-525793;Reactome: R-HSA-8950505;Reactome: R-HSA-5663213;Reactome: R-HSA-5625970;Reactome: R-HSA-418885;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8964616;Reactome: R-HSA-5663220;Reactome: R-HSA-389359;Reactome: R-HSA-4420097;Reactome: R-HSA-428543;Reactome: R-HSA-5687128;Reactome: R-HSA-182971;Reactome: R-HSA-194840;Reactome: R-HSA-5626467 "Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade";"RHO GTPases activate PAKs";"Myogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate KTN1";"DCC mediated attractive signaling";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"G beta:gamma signalling through CDC42";"RHO GTPases Activate Formins";"CD28 dependent Vav1 pathway";"VEGFA-VEGFR2 Pathway";"Inactivation of CDC42 and RAC1";"MAPK6/MAPK4 signaling";"EGFR downregulation";"Rho GTPase cycle";"RHO GTPases activate IQGAPs" XP_012238896.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024227544.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012239641.1 8 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human papillomavirus infection" XP_003492725.1 5 Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225 "HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_024220839.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_003490741.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024223007.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_003486637.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_012238212.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024221236.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003494750.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1362277 "G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex" XP_012240977.1 16 Reactome: R-HSA-5603041;Reactome: R-HSA-5602498;Reactome: R-HSA-5603037;Reactome: R-HSA-209543;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-3134963;Reactome: R-HSA-9020702;Reactome: R-HSA-975155;Reactome: R-HSA-1236974;Reactome: R-HSA-975110;Reactome: R-HSA-1810476;Reactome: R-HSA-5602680;Reactome: R-HSA-1257604;Reactome: R-HSA-975138;Reactome: R-HSA-6811558 "IRAK4 deficiency (TLR2/4)";"MyD88 deficiency (TLR2/4)";"IRAK4 deficiency (TLR5)";"p75NTR recruits signalling complexes";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"Interleukin-1 signaling";"MyD88 dependent cascade initiated on endosome";"ER-Phagosome pathway";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR5)";"PIP3 activates AKT signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_024224311.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_012243474.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003488028.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841 "Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines" XP_012249461.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_003486723.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003489688.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_024227512.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003486663.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003487455.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_012236361.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012239638.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Mitotic Prometaphase";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"HCMV Early Events";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins" XP_024223614.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_003492870.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_024226197.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_012248016.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024226896.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012245838.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012247013.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024224047.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_024227976.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_024225439.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003485620.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling" XP_012240624.1 5 MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346 "Protein ubiquitination";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis" XP_003484593.1 9 Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685942 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)" XP_012236892.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012242287.1 8 KEGG: 00030+2.2.1.2;MetaCyc: PWY-5723;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462;Reactome: R-HSA-71336;MetaCyc: PWY-1861 "Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_024222897.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012245851.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003485348.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_024222146.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718 "PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes" XP_003489574.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_003488528.1 8 MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241 "3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" XP_024225880.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-9617324 "Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_003490080.1 57 Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870 "ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins" XP_024227318.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012249783.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_012246930.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003494376.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012240393.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" XP_012249910.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012236316.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_003485120.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003490246.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024225326.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_012247342.1 13 MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Citrate cycle (TCA cycle)" XP_012240788.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012242117.1 16 Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723 "Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation" XP_024221190.1 6 Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_024226516.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012238935.1 2 Reactome: R-HSA-9029569;Reactome: R-HSA-804914 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids" XP_012247527.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003492666.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-6798695 "WNT ligand biogenesis and trafficking";"Neutrophil degranulation" XP_012247935.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003494130.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_024222501.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "ECM proteoglycans";"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_012241416.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024222524.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_024224590.1 6 Reactome: R-HSA-5685939;Reactome: R-HSA-162594;Reactome: R-HSA-69166;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-174437 "HDR through MMEJ (alt-NHEJ)";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand" XP_003491206.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685 "Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy" XP_024228195.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024225938.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_003489659.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012244569.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_024227437.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003493337.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012244309.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_003485214.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_012236719.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_024223542.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_003484810.2 7 KEGG: 00072+4.1.3.4;Reactome: R-HSA-77111;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00281+4.1.3.4 "Synthesis and degradation of ketone bodies";"Synthesis of Ketone Bodies";"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Peroxisomal protein import";"Geraniol degradation" XP_003487165.1 42 KEGG: 00592+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-6435;KEGG: 00627+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-6945;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-5136;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-6946;MetaCyc: PWY-1361;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-6583;MetaCyc: PWY-7778;KEGG: 00623+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-5138;KEGG: 00360+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-5109;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-6944;MetaCyc: PWY-7401;MetaCyc: PWY-7216;MetaCyc: PWY-7094 "alpha-Linolenic acid metabolism";"Limonene and pinene degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Geraniol degradation";"Pyruvate fermentation to butanol II (engineered)";"4-hydroxybenzoate biosynthesis III (plants)";"Aminobenzoate degradation";"Fatty acid degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Butanoate metabolism";"Glutaryl-coa degradation";"Tryptophan metabolism";"Fatty acid degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Benzoyl-coa degradation I (aerobic)";"Lysine degradation";"Valine, leucine and isoleucine degradation";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to butanol I";"2-methylpropene degradation";"Toluene degradation";"Benzoate degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Phenylalanine metabolism";"Fatty acid elongation";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Methyl ketone biosynthesis (engineered)";"Fermentation to 2-methylbutanoate";"Butanoate metabolism";"Caprolactam degradation";"Spodoptera littoralis pheromone biosynthesis";"Androstenedione degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid salvage" XP_003490720.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_012240763.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024221191.1 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)" XP_003491329.1 56 Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702 "TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"UCH proteinases";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling" XP_024221885.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events" XP_024226843.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003491743.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_012248636.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_024225014.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012236145.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_012243331.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_003489236.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_003489682.1 27 Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-167200;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-159227;Reactome: R-HSA-6807505;Reactome: R-HSA-111367;Reactome: R-HSA-72203;Reactome: R-HSA-975956;Reactome: R-HSA-112382;Reactome: R-HSA-975957;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-72187;Reactome: R-HSA-167152;Reactome: R-HSA-77588;Reactome: R-HSA-72086;Reactome: R-HSA-77595;Reactome: R-HSA-9010553;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Transport of the SLBP independent Mature mRNA";"RNA polymerase II transcribes snRNA genes";"SLBP independent Processing of Histone Pre-mRNAs";"Processing of Capped Intron-Containing Pre-mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of RNA Pol II elongation complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"mRNA 3'-end processing";"Formation of HIV elongation complex in the absence of HIV Tat";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Capping";"Processing of Intronless Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway" XP_012245810.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003493539.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_003494113.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003486169.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events" XP_024224742.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_024227863.1 12 MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism" XP_012244525.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_012240929.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_024225585.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012244715.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024220923.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012239894.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003491272.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_024226734.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_024222373.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012245848.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_003488751.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_003493276.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_003492357.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_003486621.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012240702.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_012244646.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_024222685.1 9 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)" XP_024220292.1 14 Reactome: R-HSA-8964208;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-801;MetaCyc: PWY-6936;Reactome: R-HSA-8964539;KEGG: 00380+2.6.1.7;MetaCyc: PWY-7901;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-1187 "Phenylalanine metabolism";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"Glutamate and glutamine metabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine" XP_024221517.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012244733.1 4 MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726 "Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation" XP_024227809.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_003493760.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024226652.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_024223951.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003491066.2 5 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_024225573.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012236504.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024221193.1 6 Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143 "Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis" XP_024220962.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_012245091.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_003492277.1 19 Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825 "Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"VLDL assembly";"LDL remodeling";"Scavenging by Class F Receptors";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Chylomicron clearance";"Platelet sensitization by LDL";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis" XP_012242007.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation" XP_024224110.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_012242508.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012245616.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024221940.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024221484.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_012236287.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024228109.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012237818.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003487783.2 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" XP_024223646.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003493851.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012246342.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024222692.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_012236788.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003485711.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_024223448.1 15 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-912446 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination" XP_012246701.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024221617.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_024227696.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_003484912.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport" XP_003492440.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_003491547.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_012239685.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003493395.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_012243208.1 14 MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis" XP_003486793.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012237295.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003492638.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003486195.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_024225058.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012246797.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_003494406.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024227810.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_024222389.1 9 Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-174411 "Polymerase switching";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere" XP_012245924.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_024225533.1 13 Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-3000157;Reactome: R-HSA-216083;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-419037;Reactome: R-HSA-1442490;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-2214320 "Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Laminin interactions";"Integrin cell surface interactions";"Signaling by PDGF";"Collagen chain trimerization";"NCAM1 interactions";"Collagen degradation";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Anchoring fibril formation" XP_012247849.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012246767.1 2 Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Methylation";"Eukaryotic Translation Termination" XP_012241138.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003484504.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508 "Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_012248507.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_024225406.1 19 KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;Reactome: R-HSA-163765;MetaCyc: PWY-7384;MetaCyc: PWY-5172;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00720+2.3.3.8 "Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes" XP_012242703.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024221161.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_024227336.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003488646.1 56 Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178 "Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"UCH proteinases";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_024226040.1 14 Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158 "Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex" XP_012248261.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012244751.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_024227811.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_012245201.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" XP_024226593.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012244691.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497 "HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_024223120.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-977225 "TBC/RABGAPs";"Amyloid fiber formation" XP_003494426.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_003493745.1 26 Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic" XP_024223846.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024227329.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003489377.1 19 Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-3214858;Reactome: R-HSA-1799339;Reactome: R-HSA-8876725;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"RMTs methylate histone arginines";"SRP-dependent cotranslational protein targeting to membrane";"Protein methylation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_024222434.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024221599.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-2219530 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_012244238.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_012244183.1 14 KEGG: 00770+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5057;MetaCyc: PWY-5101;MetaCyc: PWY-5108;MetaCyc: PWY-5103;MetaCyc: PWY-7767;KEGG: 00270+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5104 "Pantothenate and CoA biosynthesis";"Branched-chain amino acid catabolism";"L-valine degradation II";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis III";"L-leucine degradation IV (Stickland reaction)";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis";"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"Valine, leucine and isoleucine biosynthesis";"L-leucine degradation III";"L-isoleucine biosynthesis IV" XP_012238565.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_012242863.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_003490054.1 7 KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1 "Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" XP_024220862.1 12 Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04714+2.7.11.1 "DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"Human papillomavirus infection";"mTOR signaling pathway";"Rho GTPase cycle";"Human cytomegalovirus infection";"G alpha (q) signalling events";"Thermogenesis" XP_003489086.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003487702.2 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_012242183.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012236560.2 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_003493676.1 18 MetaCyc: PWY-6638;MetaCyc: PWY-5913;KEGG: 00710+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6643;MetaCyc: PWY-6642;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00250+2.6.1.1 "Sulfolactate degradation III";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Arginine biosynthesis";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Coenzyme M biosynthesis II";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism" XP_012238950.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003486342.1 8 Reactome: R-HSA-418889;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Caspase activation via Dependence Receptors in the absence of ligand";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_012239764.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_012247992.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012247591.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012240760.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024225037.1 4 MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163 "Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism" XP_024221578.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68689 "Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_003485893.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_024225241.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003491713.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_012242444.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_003490892.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012241620.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_003493032.1 12 Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-76066 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_012245682.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_024226367.1 19 Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3000497 "VLDL clearance";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"VLDL assembly";"Scavenging by Class F Receptors";"LDL remodeling";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Platelet sensitization by LDL";"Chylomicron clearance";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors" XP_012241752.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024227025.1 13 MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7227 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_003494659.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024224200.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024223594.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_012241854.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003487117.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_024223043.1 5 Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)" XP_012245518.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012245809.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_003488036.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_003490589.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_024220717.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012239804.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024224996.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003487531.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003487998.1 17 Reactome: R-HSA-139915;Reactome: R-HSA-69656;Reactome: R-HSA-9616222;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-1912408;Reactome: R-HSA-111448;Reactome: R-HSA-8953750;Reactome: R-HSA-1362300;Reactome: R-HSA-2559585;Reactome: R-HSA-69202;Reactome: R-HSA-6804114;Reactome: R-HSA-2559580;Reactome: R-HSA-2173796;Reactome: R-HSA-113501;Reactome: R-HSA-69231 "Activation of PUMA and translocation to mitochondria";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional regulation of granulopoiesis";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Pre-NOTCH Transcription and Translation";"Activation of NOXA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Oncogene Induced Senescence";"Cyclin E associated events during G1/S transition";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Oxidative Stress Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin D associated events in G1" XP_024226178.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4085377 "Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins" XP_024223652.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" XP_024224948.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_003489844.1 10 KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41 "Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism" XP_012242864.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_003488542.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012237736.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024221097.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_024221380.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_012237754.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_012240137.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012247259.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_024220281.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_012244416.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012249174.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012236384.1 29 Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5685938;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5685942;Reactome: R-HSA-6803204;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-6803207;Reactome: R-HSA-6804760;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-912446;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-3371453 "TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Human papillomavirus infection";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"mTOR signaling pathway";"Thermogenesis";"HDR through Single Strand Annealing (SSA)";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Methylation";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Autodegradation of the E3 ubiquitin ligase COP1";"Meiotic recombination";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Human immunodeficiency virus 1 infection";"Stabilization of p53";"Regulation of HSF1-mediated heat shock response" XP_012244562.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024228095.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012238939.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_003485116.1 5 Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_003489605.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012247455.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277 "G0 and Early G1";"Cyclin D associated events in G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex" XP_024220976.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_012240484.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012247707.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_024221007.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_024227807.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_003492633.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012250354.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_003494501.1 13 MetaCyc: PWY-7184;Reactome: R-HSA-74259;MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00740+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine catabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Purine metabolism";"Purine metabolism";"Riboflavin metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_024226677.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_012244939.1 6 MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-7442;MetaCyc: PWY-6983;Reactome: R-HSA-1474151 "Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_012240279.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_012240804.1 27 Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168271 "NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus" XP_003489248.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003494150.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003490801.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_012248090.1 5 Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" XP_012241743.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024223559.1 33 Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-170822 "Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_024225672.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_024226712.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_012247895.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_024227090.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_012244519.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_024221230.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003494461.1 8 Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69166 "Polymerase switching";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate" XP_024225593.1 3 KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis" XP_012238894.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024220557.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012243567.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003489852.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_012245415.1 3 Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis" XP_003494172.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012246554.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024226781.1 7 MetaCyc: PWY-6545;KEGG: 00730+3.6.1.15;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7185 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP dephosphorylation I" XP_003492564.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_024220948.1 3 Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300 "Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors" XP_012246572.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37 "NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"DNA methylation";"Cysteine and methionine metabolism" XP_012249330.1 5 KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853 "Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)" XP_024222895.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012239161.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_003488410.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_003491139.1 6 MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_012241016.1 12 KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.2;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121;Reactome: R-HSA-73817 "Purine metabolism";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Biotin transport and metabolism";"One carbon pool by folate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis" XP_024226018.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-203927 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis" XP_024224198.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012248073.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_003488421.2 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange" XP_012239331.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003489581.1 4 Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519 "ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase";"Estrogen-dependent gene expression" XP_012247902.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_024226799.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012237826.1 26 Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-190861 "EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Separation of Sister Chromatids";"Gap junction assembly" XP_024223220.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003485979.1 7 MetaCyc: PWY-4984;MetaCyc: PWY-31;KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-46;Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1 "Urea cycle";"Canavanine degradation";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Putrescine biosynthesis III";"Urea cycle";"Arginine biosynthesis" XP_012240752.1 19 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-3214858;Reactome: R-HSA-72695;Reactome: R-HSA-8876725;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"RMTs methylate histone arginines";"Formation of the ternary complex, and subsequently, the 43S complex";"Protein methylation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024220228.1 10 Reactome: R-HSA-427413;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017 "NoRC negatively regulates rRNA expression";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_012248923.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint" XP_012250052.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_024221491.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012240037.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_024223693.1 9 KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_012242269.1 5 Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514 "Glycolysis";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_012239325.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_012237237.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_012238600.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012249661.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_024225925.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024228066.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_012249015.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024227602.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003488975.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602 "(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_024221675.1 7 Reactome: R-HSA-5693571;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565 "Nonhomologous End-Joining (NHEJ)";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_003488035.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation" XP_012243661.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012236955.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_012237863.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_003490017.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012240111.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_024220724.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_012248808.1 14 Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167158 "Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex" XP_012241827.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012241337.1 7 KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;MetaCyc: PWY-5129;MetaCyc: PWY-7838;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;MetaCyc: PWY-7839 "Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis" XP_024220603.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-983168 "Macroautophagy";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012249787.1 12 KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;MetaCyc: PWY-6683;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4 "Sulfur metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Purine metabolism";"Monobactam biosynthesis";"Selenocompound metabolism";"Transport and synthesis of PAPS";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Assimilatory sulfate reduction III";"Sulfite oxidation III";"Purine metabolism" XP_024225874.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9617324 "Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Trafficking of AMPA receptors";"Long-term potentiation";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_024223351.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012245594.2 18 MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4 "Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Synthesis of PA";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism" XP_003491532.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation" XP_024227647.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_012245804.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_024220262.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_012245225.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_024221840.1 3 MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493 "Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2" XP_012248726.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_003488127.1 19 MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-1622 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Cysteine and methionine metabolism";"Gluconeogenesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)" XP_012239623.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024226699.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_024223641.1 10 Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922 "Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_012245504.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012239501.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012245692.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_024221964.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_024222846.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_003488137.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression" XP_024221120.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012243087.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-7589 "Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)" XP_012247468.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012243443.1 11 MetaCyc: PWY-3861;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-3881;MetaCyc: PWY-5659;MetaCyc: PWY-6992;Reactome: R-HSA-4043916;KEGG: 00520+5.3.1.8;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205 "Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Synthesis of GDP-mannose" XP_003490911.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_012248257.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_003493426.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_024223792.1 2 Reactome: R-HSA-2564830;Reactome: R-HSA-83936 "Cytosolic iron-sulfur cluster assembly";"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_003486408.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_003488000.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_012250099.1 7 Reactome: R-HSA-4641258;Reactome: R-HSA-201681;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-4086400;Reactome: R-HSA-201688 "Degradation of DVL";"TCF dependent signaling in response to WNT";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"PCP/CE pathway";"WNT mediated activation of DVL" XP_012238455.1 3 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_012242760.1 11 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-383280;Reactome: R-HSA-212436;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Nuclear Receptor transcription pathway";"Generic Transcription Pathway";"RORA activates gene expression";"Estrogen-dependent gene expression" XP_024224193.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_003493366.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012246707.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024223085.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_003484754.1 10 Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837 "Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation" XP_003486613.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_003486784.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_024221825.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012244648.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_024223790.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012249434.1 15 MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-6901;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-2221;Reactome: R-HSA-70171 "Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis" XP_012250384.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003486108.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_012239021.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012240380.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-264870;Reactome: R-HSA-6798695 "Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation" XP_012239914.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_003486194.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_003485597.1 4 Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922 "Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_024226801.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_012240192.1 16 MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-2046106;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7036;Reactome: R-HSA-2046105;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199 "Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"alpha-linolenic acid (ALA) metabolism";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Linoleic acid (LA) metabolism";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation" XP_003486552.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012244793.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_003485035.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012241321.1 11 Reactome: R-HSA-6804114;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400206 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha" XP_012248706.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012240561.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012245770.1 9 Reactome: R-HSA-3304356;Reactome: R-HSA-5689603;Reactome: R-HSA-3645790;Reactome: R-HSA-2173791;Reactome: R-HSA-3656535;Reactome: R-HSA-3642279;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789 "SMAD2/3 Phosphorylation Motif Mutants in Cancer";"UCH proteinases";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs" XP_024226405.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003489753.1 4 Reactome: R-HSA-975871;Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-6799198 "MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis" XP_024220880.1 12 KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"mTOR signaling pathway";"G alpha (q) signalling events";"Human cytomegalovirus infection";"Thermogenesis";"NRAGE signals death through JNK";"Human papillomavirus infection" XP_003486575.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_012242421.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_003485158.2 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_003492569.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_012246575.1 5 Reactome: R-HSA-212300;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-4655427 "PRC2 methylates histones and DNA";"DNA methylation";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins" XP_003491461.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_024228163.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_003486306.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72702 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition" XP_012240940.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_012249683.1 4 MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6 "S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism" XP_003486064.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_012241146.1 7 KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219 "Drug metabolism - other enzymes";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_012248547.1 18 Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-7417 "Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Synthesis of PA";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)" XP_024223811.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012237758.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012237131.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_012243597.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_024226011.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" XP_003486538.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_003494446.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012243056.1 3 KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_024221129.1 26 Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-389960 "COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Separation of Sister Chromatids";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC" XP_003491362.2 4 MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163 "Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism" XP_012240615.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins" XP_012244235.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation" XP_012238217.1 4 Reactome: R-HSA-5674400;Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399 "Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors" XP_024223613.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_003488541.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_024220649.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012239489.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024227815.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_003487004.2 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_003488783.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024222567.1 7 Reactome: R-HSA-9033241;KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;Reactome: R-HSA-77111;MetaCyc: PWY-5074 "Peroxisomal protein import";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Synthesis of Ketone Bodies";"Mevalonate degradation" XP_012241959.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_012244692.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_012243002.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012245366.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_003488957.1 9 Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928 "Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis" XP_012247021.1 4 MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22 "Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism" XP_012246956.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_024223905.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_003484493.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_012247466.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003490229.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_012248113.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_024228399.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-5218921 "DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Ca2+ pathway";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation" XP_003487533.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_024226895.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_024220782.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024222757.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012238478.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_003492940.1 7 Reactome: R-HSA-5689880;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-171319;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"Telomere Extension By Telomerase";"UCH proteinases" XP_012243503.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_024228140.1 4 Reactome: R-HSA-70688;MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2 "Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_003489974.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_003491233.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_003484488.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_012249903.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024224168.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_024226257.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_003494017.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_024226907.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_012247994.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012244718.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport" XP_024223093.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_012239471.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003494430.1 9 MetaCyc: PWY-6142;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-70263;MetaCyc: PWY-8086 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_024227261.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_003491249.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012246405.1 15 Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-6807505 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"RNA polymerase II transcribes snRNA genes" XP_012248514.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012237199.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012247177.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024220317.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_012243206.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972 "Sciadonate biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)" XP_024223941.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012248013.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_024227485.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_012240513.1 6 Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-73930 "POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway" XP_003491471.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_024220432.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68962 "Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex" XP_024225694.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003490257.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_012245836.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_012241889.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003493908.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_024221117.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012239401.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_012250053.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_003486396.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003486526.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012239830.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003492079.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_003489329.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_012237232.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_024225106.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_012244684.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_024220327.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_012247454.1 7 Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69231 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin D associated events in G1" XP_024226041.1 14 Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648 "Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes" XP_024223809.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_024223452.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003493410.1 3 Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691 "Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway";"Interleukin-20 family signaling" XP_012244588.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_012247120.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024227034.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948 "Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants" XP_024224540.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024224656.1 8 Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;MetaCyc: PWY-7221 "Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis" XP_012245365.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024226909.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_024221678.1 4 KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14 "Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Nitrogen metabolism" XP_012245109.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_012240765.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024220575.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012249248.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_003490910.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_012238831.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003492111.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003486292.2 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_024225359.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012245048.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003487969.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_012249120.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012245711.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_012244673.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_024226834.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012237669.2 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_012244717.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_003487616.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_024223710.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012239099.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_003487894.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_012247471.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_012246420.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_024224361.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_003489847.1 42 Reactome: R-HSA-110331;Reactome: R-HSA-3214858;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-4551638;Reactome: R-HSA-5693571;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-427389;Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-1912408;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-5250924;Reactome: R-HSA-110328;Reactome: R-HSA-2559582;Reactome: R-HSA-3214847;Reactome: R-HSA-73728;Reactome: R-HSA-8936459;Reactome: R-HSA-5693607;Reactome: R-HSA-9609690;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-5625886;Reactome: R-HSA-5578749;Reactome: R-HSA-2299718;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222 "Cleavage of the damaged purine";"RMTs methylate histone arginines";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"SUMOylation of chromatin organization proteins";"Nonhomologous End-Joining (NHEJ)";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Pre-NOTCH Transcription and Translation";"Amyloid fiber formation";"Meiotic synapsis";"B-WICH complex positively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Senescence-Associated Secretory Phenotype (SASP)";"HATs acetylate histones";"RNA Polymerase I Promoter Opening";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Processing of DNA double-strand break ends";"HCMV Early Events";"DNA methylation";"HCMV Late Events";"Cleavage of the damaged pyrimidine";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Transcriptional regulation by small RNAs";"Condensation of Prophase Chromosomes";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis" XP_024221074.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012246789.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_012242548.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012243859.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024222078.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_024227327.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003486760.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012237204.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_012244037.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_003484835.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012244904.1 8 Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Activation of RAC1";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_012247174.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024224547.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012249583.1 12 Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-429947 "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA" XP_003485089.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024224001.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_012236503.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012245446.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003493906.1 5 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis" XP_003486749.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012243543.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003487163.1 18 Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_003490405.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_024224485.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization" XP_012243090.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" XP_024227601.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003490232.1 17 MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7205;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism" XP_003485004.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003494883.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_012248417.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_012240772.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003491487.1 4 Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" XP_024225215.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_012246571.1 5 Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-4655427 "PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins" XP_012245837.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_003492977.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_012249453.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_003492628.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024227521.1 1 Reactome: R-HSA-8963901 "Chylomicron remodeling" XP_024224472.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_012242415.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_024222056.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_012244747.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003486090.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024220980.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_012238953.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003492503.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_024227189.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024225719.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012245367.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_024224754.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_024222964.1 6 Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-5609978 "Galactose catabolism";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia" XP_024224049.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024220855.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012247269.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_012245702.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024222435.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_003488789.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_003487913.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003491024.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012238866.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Justicidin B biosynthesis" XP_003487648.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_024223565.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003491271.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003485872.1 6 MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_012241405.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_003484964.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_012238515.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024228199.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_024220481.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024227806.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_024223022.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism" XP_024226873.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012241947.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003488239.1 18 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-166208;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_024224074.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012243428.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012240503.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_024220573.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012245333.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_024226199.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_003484945.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" XP_012247596.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024226264.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_024224887.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265 "Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes" XP_024224847.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_012243905.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024226135.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003488207.1 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" XP_024220259.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_012244906.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024224787.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024222255.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_024226287.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_012246651.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012240094.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_024223297.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_024220820.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003486856.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012247045.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740 "Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs" XP_012239126.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_024225890.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244 "Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Ion homeostasis";"RAF activation";"Long-term potentiation" XP_024225887.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-438066 "Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Trafficking of AMPA receptors";"RAF activation";"Long-term potentiation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation" XP_024227295.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_003493531.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-3232142 "Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"SUMOylation of ubiquitinylation proteins" XP_024228224.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_003494500.3 19 Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-8856825 "Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"VLDL assembly";"Scavenging by Class F Receptors";"LDL remodeling";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Chylomicron clearance";"LDL clearance";"Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis" XP_012250055.1 27 Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins" XP_003488200.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" XP_024221098.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_012242115.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408 "Transcriptional Regulation by VENTX";"Ca2+ pathway";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation" XP_024223544.1 20 Reactome: R-HSA-176187;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "Activation of ATR in response to replication stress";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Processing of DNA double-strand break ends";"Polymerase switching";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_012244411.1 17 Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-174414;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5656169 "PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the C-strand of the telomere";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis" XP_012237111.1 6 MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_003488743.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_003487030.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_003494509.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_012243217.2 4 Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012249702.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_024224378.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_024222582.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_012239157.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024227334.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003491040.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080 "Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" XP_003491774.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_024222143.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_003488092.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_024226105.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012248418.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_024225217.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_012240306.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_003485778.1 13 KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902 "Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Other glycan degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)" XP_012250179.1 5 Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341 "Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors" XP_024223640.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012249703.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_024227136.1 5 Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787;Reactome: R-HSA-373080 "Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Hedgehog 'off' state";"Class B/2 (Secretin family receptors)" XP_003491809.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_003485086.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_024227518.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_024220234.1 7 Reactome: R-HSA-4086400;Reactome: R-HSA-201688;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-4641258 "PCP/CE pathway";"WNT mediated activation of DVL";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"Degradation of DVL" XP_003492885.2 57 Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-75815 "FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D" XP_003494918.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012238579.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_024225633.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_024221043.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_003486701.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339 "Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane" XP_003488182.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-168638 "mTOR signaling pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"NOD1/2 Signaling Pathway" XP_003487177.1 57 Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050 "Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"UCH proteinases";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_024223343.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012245073.1 16 Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176412 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Phosphorylation of the APC/C" XP_024225380.1 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_003487646.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_003484743.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012239013.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_024222556.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_012244112.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_003488887.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_012244709.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6807878 "Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport" XP_024226007.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_024227882.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012240336.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_012237689.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012237568.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_012246140.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_012239848.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012247740.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_012239803.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012247096.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003485877.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_024221618.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003489695.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012241804.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012237252.2 8 KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27 "Propanoate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis" XP_012245821.1 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_024228047.1 10 KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6369;MetaCyc: PWY-6361;MetaCyc: PWY-6362 "Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_003492590.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003488222.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_012241856.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003490122.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_024220933.1 3 Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989 "TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" XP_012247208.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_024224082.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012239941.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15 "Synthesis of PA";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_012236522.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_012239224.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012248492.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012241258.1 7 Reactome: R-HSA-168333;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-165054 "NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA" XP_003492116.1 6 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape" XP_012238584.1 4 KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9;Reactome: R-HSA-390247;Reactome: R-HSA-9033241 "Propanoate metabolism";"beta-Alanine metabolism";"Beta-oxidation of very long chain fatty acids";"Peroxisomal protein import" XP_003489963.1 4 MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662 "Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism" XP_012243569.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012244468.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642 "Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_012242956.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_024224500.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012243616.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_024228503.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003484909.1 14 MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis" XP_024228364.1 9 Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664 "Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Neddylation" XP_012239101.1 5 Reactome: R-HSA-5545619;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880 "XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases" XP_012240224.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012239502.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_003493244.2 3 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-948021 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification" XP_012247325.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_024223748.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_012244981.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_003490222.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003487745.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_012247268.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_012247040.1 10 MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Galactose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)" XP_003487500.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012249888.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003485209.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642 "Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle" XP_024222008.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_012246685.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_003491728.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_003489347.1 15 Reactome: R-HSA-5358752;Reactome: R-HSA-5467333;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-3769402;Reactome: R-HSA-5358751;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-195253 "T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Deactivation of the beta-catenin transactivating complex";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex" XP_024222126.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7 "Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis" XP_012247049.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_024222290.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_003487110.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_003490999.1 14 MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis" XP_003485770.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024224499.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024222815.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012243232.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5080 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_012247726.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_012248899.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024223226.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012246914.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024221122.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012247440.1 5 KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22 "Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism" XP_012242089.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012241705.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_012237690.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012240389.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003485751.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_024223254.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012247431.1 5 Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3 "Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism" XP_024224166.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_024224097.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_024225663.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_012244928.1 56 Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68949 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"UCH proteinases";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin" XP_012246865.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-164843 "Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation" XP_012250177.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_012246743.2 8 KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism" XP_012236720.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553 "mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs" XP_012249432.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024223346.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012249450.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_012245065.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012241637.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_024223898.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_012237965.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_003489662.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_003492665.1 10 MetaCyc: PWY-6537;Reactome: R-HSA-916853;MetaCyc: PWY-5022;MetaCyc: PWY-6536;MetaCyc: PWY-6535;KEGG: 00250+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00410+2.6.1.19;KEGG: 00640+2.6.1.19 "4-aminobutanoate degradation II";"Degradation of GABA";"4-aminobutanoate degradation V";"4-aminobutanoate degradation III";"4-aminobutanoate degradation I";"Alanine, aspartate and glutamate metabolism";"Butanoate metabolism";"L-glutamate degradation IV";"beta-Alanine metabolism";"Propanoate metabolism" XP_003489071.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024220947.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_012246716.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_012250042.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024223546.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_003488795.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_024221436.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012250005.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012245012.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012237052.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012249891.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane" XP_003494715.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_003487754.1 4 KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4 "Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Folate biosynthesis" XP_003492814.1 7 Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4 "Synthesis of PA";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism" XP_012239364.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_003488555.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012237234.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003486525.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012244714.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497 "Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_003485614.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_012236711.1 14 Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-4086398;Reactome: R-HSA-434316;KEGG: 04070+3.1.4.11;Reactome: R-HSA-399997;Reactome: R-HSA-418217;Reactome: R-HSA-500657;MetaCyc: PWY-6367;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-1855204 "PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Ca2+ pathway";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidylinositol signaling system";"Acetylcholine regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol" XP_003490851.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_024224300.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_003491364.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012247350.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003490453.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_012239419.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_024225260.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_003491725.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_024228471.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_012239892.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012243563.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003487555.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_003493727.2 6 MetaCyc: PWY-6829;Reactome: R-HSA-8868766;MetaCyc: PWY-7286;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;MetaCyc: PWY-7285 "Trna methylation (yeast)";"rRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"Methylwyosine biosynthesis" XP_012236190.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6802952 "Neutrophil degranulation";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions" XP_024226861.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035 "TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_024227134.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_012237294.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003493499.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012244882.1 5 KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_003490750.1 30 Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-2644607;Reactome: R-HSA-9604323;Reactome: R-HSA-2894862;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-1170546;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-2565942;Reactome: R-HSA-2122947;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-5610780;Reactome: R-HSA-917937;Reactome: R-HSA-69231;Reactome: R-HSA-5684264 "Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Prolactin receptor signaling";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition";"NOTCH1 Intracellular Domain Regulates Transcription";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Degradation of GLI1 by the proteasome";"Iron uptake and transport";"Cyclin D associated events in G1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation" XP_024220257.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events" XP_012237211.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_024220729.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_003494934.2 13 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_012241442.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_024224987.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_024222286.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_003492046.1 5 MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37 "Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism" XP_012245679.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_024224281.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012240828.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_024222837.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012247059.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_024227469.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_003494429.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_024228460.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_024225200.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844 "Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_024222043.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003491229.1 6 MetaCyc: PWY-7765;KEGG: 00380+1.14.13.9;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-7717;MetaCyc: PWY-5651 "3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde" XP_012236279.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_012237968.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_012248268.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012238745.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_012247534.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012239794.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012245842.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_003494052.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_012236133.1 8 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Caspase activation via Dependence Receptors in the absence of ligand";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_024228111.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024228097.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003486618.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_012240233.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003490777.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012238432.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_012250066.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012247925.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012249532.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003493164.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003486349.2 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241 "Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import" XP_024224796.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012243828.1 19 MetaCyc: PWY-5172;MetaCyc: PWY-7384;Reactome: R-HSA-163765;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537 "Acetyl-coa biosynthesis III (from citrate)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"ChREBP activates metabolic gene expression";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Pyruvate fermentation to acetate V" XP_012249475.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression" XP_003486847.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_003485208.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_024228265.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_012236296.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024223634.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_024221061.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_012236422.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003490266.1 5 KEGG: 00680+1.1.1.95;KEGG: 00260+1.1.1.95;MetaCyc: PWY-8010;KEGG: 00270+1.1.1.95;Reactome: R-HSA-977347 "Methane metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Serine biosynthesis" XP_024221438.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012245069.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012238705.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012243100.1 10 Reactome: R-HSA-9648895;Reactome: R-HSA-72695;Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-382556;Reactome: R-HSA-72731;Reactome: R-HSA-72702 "Response of EIF2AK1 (HRI) to heme deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ABC-family proteins mediated transport";"Recycling of eIF2:GDP";"Ribosomal scanning and start codon recognition" XP_003484905.1 7 KEGG: 00510+2.7.8.15;Reactome: R-HSA-4549356;MetaCyc: PWY-6471;Reactome: R-HSA-446193;MetaCyc: PWY-6470;KEGG: 00550+2.7.8.13;MetaCyc: PWY-5265 "N-Glycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)" XP_003487605.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003493038.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_003492936.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_003489025.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012249111.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012237235.1 7 MetaCyc: PWY-6352;Reactome: R-HSA-1660516;MetaCyc: PWY-6351;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67 "3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system" XP_012245921.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_003487058.2 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_003485186.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012243418.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_003485820.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024224247.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012245651.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024220433.1 3 KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286 "One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation" XP_003486345.1 6 Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_024226892.1 6 Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648 "Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes" XP_024227835.1 14 MetaCyc: PWY-6606;MetaCyc: PWY-5695;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-6608;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6999;Reactome: R-HSA-8851680;KEGG: 00232+1.17.3.2;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6538;Reactome: R-HSA-74259 "Guanosine nucleotides degradation II";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Theophylline degradation";"Butyrophilin (BTN) family interactions";"Caffeine metabolism";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Purine catabolism" XP_024228187.1 7 Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_003492676.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012240974.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012239227.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003485880.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_003490671.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_003494937.2 4 MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate" XP_003486844.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_012248745.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012238694.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_024221123.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012250236.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_012239701.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_024226104.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024224779.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012236651.1 10 KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6397;MetaCyc: PWY-7344;MetaCyc: PWY-3821 "Galactose metabolism";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification" XP_012246235.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_024224170.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012238131.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_012242366.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_003493419.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_003491224.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_024225878.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"Long-term potentiation";"RAF activation";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Trafficking of AMPA receptors" XP_012245599.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_024223103.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003484948.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" XP_003487448.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003490821.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012239627.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_003486834.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_012242511.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_003485084.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003485276.1 10 Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172 "RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome" XP_024222453.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594 "Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events" XP_024220562.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024228147.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012247314.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024228370.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_012240979.1 5 Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166 "IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade" XP_024227478.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003493129.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-5689880 "Macroautophagy";"Ub-specific processing proteases" XP_012239242.1 3 MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7 "5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_012247828.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_012236127.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism" XP_024221828.1 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" XP_024224651.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_003487834.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPII-mediated vesicle transport" XP_024228297.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012248452.2 14 MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051 "Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis I" XP_003490424.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_012242330.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis" XP_024225446.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024228135.1 7 MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351 "Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_012243302.1 7 MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941;Reactome: R-HSA-6798695 "Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen degradation II";"Neutrophil degranulation" XP_012242292.1 4 Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_024223299.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_012243485.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_012245491.1 14 Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex" XP_003485320.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012246421.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003490153.1 10 Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-111459 "Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage" XP_003487503.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012249699.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_003485968.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003485661.1 8 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-167590 "Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation" XP_012239165.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_024226151.1 8 MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;MetaCyc: PWY-2301;KEGG: 00521+5.5.1.4;MetaCyc: PWY-4661 "Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_024220270.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_024223610.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_003487053.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003486898.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_024223033.1 9 Reactome: R-HSA-70263;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00710+1.2.1.12;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7003 "Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol" XP_012238952.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012248150.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_003494214.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_024220940.1 14 MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-399997;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-434316;KEGG: 04070+3.1.4.11;Reactome: R-HSA-500657 "D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidylinositol signaling system";"Presynaptic function of Kainate receptors" XP_012247971.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003486016.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_012243435.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024223181.1 10 MetaCyc: PWY-7199;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7187;Reactome: R-HSA-69205;Reactome: R-HSA-499943;MetaCyc: PWY-3841;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184;KEGG: 00670+2.1.1.45 "Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription";"Interconversion of nucleotide di- and triphosphates";"Folate transformations II (plants)";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"One carbon pool by folate" XP_024226645.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_003484994.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012243166.1 12 Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-447038;Reactome: R-HSA-5673001 "Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"RAF/MAP kinase cascade" XP_003488983.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972 "Sciadonate biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)" XP_012236722.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" XP_012243920.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_024222564.1 8 MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7115 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_024222217.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_012248494.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012244209.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_024221711.1 7 MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-7282;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism" XP_024222270.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_003489571.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI" XP_012245136.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012240660.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_024220420.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024220708.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024221015.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012240459.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins" XP_012247896.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_012248700.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_024222517.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012238617.1 7 MetaCyc: PWY-882;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8 "L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism" XP_024222368.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012242123.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024227539.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012243060.1 9 Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-2871796;Reactome: R-HSA-4420097;Reactome: R-HSA-193648 "FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"FCERI mediated MAPK activation";"VEGFA-VEGFR2 Pathway";"NRAGE signals death through JNK" XP_003484475.2 7 Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656 "Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry" XP_012249631.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_012245103.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003491577.1 13 Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-8866427 "Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"LDL clearance";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"VLDLR internalisation and degradation" XP_012246703.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024227194.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024227649.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_003487029.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_012239590.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_003492305.3 13 MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52 "Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_012248074.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_024225572.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024220415.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003492934.1 6 KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17 "Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation" XP_012244991.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_024220705.1 9 Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982 "Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor" XP_003492512.1 4 Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8950505;Reactome: R-HSA-8949613 "Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation" XP_012236193.1 9 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)" XP_024223957.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003486375.2 11 Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-432040 "Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Purine metabolism";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_003487069.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation" XP_012243922.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-113501 "DNA replication initiation";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Polymerase switching";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" XP_024222127.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis" XP_003492063.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" XP_024223612.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_003491585.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003489767.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_012246856.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_024226134.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012239981.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003492212.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_012237117.1 12 Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2" XP_012239733.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_024228064.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880 "G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases" XP_024228101.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012247042.1 10 KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11 "Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Galactose metabolism" XP_012248014.1 3 Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490 "Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation" XP_024223069.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695 "mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation" XP_003490638.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012242241.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662 "Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism" XP_012248441.1 12 MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053 "Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II" XP_024221433.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024226942.1 3 Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153 "eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis" XP_024225449.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024225648.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012236206.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_012238467.1 1 Reactome: R-HSA-156581 "Methylation" XP_003485391.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_012239488.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012238427.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012248620.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_024227139.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_024226904.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024224888.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398 "RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway" XP_012236280.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_003491529.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_024228191.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012242187.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_024224661.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012246151.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024220407.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012237730.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-69017 "Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6" XP_024226349.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003494418.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024222025.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6798695 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_012248788.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024225715.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_003489051.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_024220442.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012244247.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_003491754.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012241382.1 20 Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400 "PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER" XP_003492048.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_024226220.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_012245677.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_003494085.1 3 KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271 "Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"Fructose and mannose metabolism" XP_003486777.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_024221820.1 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_012248056.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_003488779.1 6 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones" XP_003493311.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_024224363.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_012245037.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012238848.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_003491074.1 15 Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling" XP_012249643.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024223347.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012243445.1 32 Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-167242 "HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_024226631.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_012243761.1 10 KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2 "Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism" XP_012242841.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024227294.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_024227378.1 11 Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange" XP_024227438.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024224025.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_003489636.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_012243496.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012249885.1 11 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway" XP_012242880.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_024227996.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_012243933.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024226592.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003487594.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003488610.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion" XP_012238001.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163615 "Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"PKA activation" XP_024220545.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_024221903.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_003489310.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_003490456.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_024224153.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_003491669.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012245140.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_003490065.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012240399.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_003488511.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_024221655.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_003490040.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_003488406.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_012239179.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012248328.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024223653.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024220282.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" XP_012249425.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473 "Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint" XP_024220781.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024228151.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012241092.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" XP_012237980.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012244383.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159231 "snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_012241103.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_003485492.1 10 KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-7909;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-1722 "One carbon pool by folate";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate" XP_012241065.1 7 Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15 "tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012243246.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization" XP_003493893.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003486168.1 3 Reactome: R-HSA-4086400;Reactome: R-HSA-373080;Reactome: R-HSA-4608870 "PCP/CE pathway";"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins" XP_012243098.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_003485289.1 14 KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-3781;MetaCyc: PWY-7279;Reactome: R-HSA-611105;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-4302 "Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration III (alternative oxidase pathway)" XP_012238756.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024220805.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024224795.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024224774.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_012245383.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation" XP_012238608.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_012238360.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003493691.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003488224.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_012250329.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012246541.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003494871.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024223768.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003494904.1 24 Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-190861 "EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Aggrephagy";"HCMV Early Events";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"MHC class II antigen presentation";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Gap junction assembly" XP_012247169.1 17 MetaCyc: PWY-6679;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2 "Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Propanoate metabolism";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Carnitine metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis" XP_024221671.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938 "Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)" XP_003490425.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_003488512.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012238951.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024220613.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_003493134.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012249805.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_012242851.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012249342.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_024223296.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_024220470.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003492752.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72702 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition" XP_012239411.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_012241848.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_024222216.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_003488889.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_024225872.1 19 Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-3371571 "Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Long-term potentiation";"RAF activation";"Trafficking of AMPA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation" XP_012247473.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_024223851.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003492701.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_003490773.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012244797.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_012244645.1 3 KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis" XP_012248242.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012243179.1 8 Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324 "Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_012249634.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003490156.2 29 Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-73863 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination" XP_012236810.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012250353.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_024221285.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003485114.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024225456.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_024223139.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012236498.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-1368082 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"RORA activates gene expression" XP_024224425.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_024223728.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_024226009.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" XP_003491564.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024221283.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012239154.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012239889.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024220448.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024220673.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_024223636.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_024228305.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012246553.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024227319.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012242197.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_003494015.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003489262.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012249961.1 13 KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2 "Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism" XP_012238035.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003491350.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003486671.1 10 Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-7344 "Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Galactose catabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis" XP_012236205.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_003485060.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_024225738.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012243000.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003490894.1 10 Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-445144 "Synthesis of PC";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Signal transduction by L1" XP_024226218.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_024226345.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012237783.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165181 "Macroautophagy";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB" XP_024222990.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_012242418.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_012250037.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024227310.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_024224998.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012244320.1 12 Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex" XP_012245102.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003491175.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_024220315.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_012246917.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_012245066.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012237466.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012238601.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024223845.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_012239016.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_003488012.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_003488387.2 9 Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-68962 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching";"G1/S-Specific Transcription";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Activation of the pre-replicative complex" XP_024223274.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024222554.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_024224289.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling" XP_024223730.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane" XP_024227230.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6952;Reactome: R-HSA-163560 "Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerol degradation I";"Glycerophosphodiester degradation";"Triglyceride catabolism" XP_003492480.1 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_024228106.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024227196.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003492500.2 15 Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700 "MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_012245815.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_012249845.1 6 MetaCyc: PWY-7442;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3 "Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism" XP_012241972.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_024225376.1 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_012249530.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_024223424.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_024220452.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012244649.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_012243244.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_024220406.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003485021.1 52 Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-5617472;Reactome: R-HSA-749476;Reactome: R-HSA-6782210;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-76061;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-168325;Reactome: R-HSA-73772;Reactome: R-HSA-72163;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-1834949;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-73780;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-76071 "Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Viral Messenger RNA Synthesis";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Major Pathway";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_003486214.1 7 KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;MetaCyc: PWY-6363 "Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_024225012.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024225117.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_012243858.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012239837.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_012240225.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012245266.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948 "Long-term potentiation";"RAF activation";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants" XP_003486855.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_024224780.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins" XP_012247010.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012237988.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003488189.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_024228005.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_024221701.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_012236524.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003489934.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024226395.1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" XP_003493580.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis" XP_012237287.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012242141.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_012246193.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003493396.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_024227977.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_012239430.1 5 MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41 "CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_012240468.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003485110.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_012237191.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_003485096.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012249172.1 8 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_012246808.2 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_024225654.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012242059.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024220751.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_012250106.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_003491765.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_024227032.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-114608 "MAP2K and MAPK activation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Platelet degranulation" XP_012242885.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024220437.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003486042.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_024223651.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012238506.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_012237716.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7 "Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis" XP_012243326.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_012237793.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-5673001 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K Cascade";"RAF/MAP kinase cascade" XP_024222172.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003493526.1 34 Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-9639288;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3301854 "SUMOylation of DNA replication proteins";"HCMV Early Events";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"Amino acids regulate mTORC1";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly" XP_012236830.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012239163.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_003493042.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72702 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition" XP_012239418.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_012246892.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003487608.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_024226642.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_024222585.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_012236835.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_024222386.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_003485573.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012245758.1 16 MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5749;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.4;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.4;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5913 "Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Itaconate degradation";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)" XP_012238289.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024220671.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_024227520.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_024224158.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012240764.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003485493.2 4 Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178 "Integrin cell surface interactions";"Syndecan interactions";"Molecules associated with elastic fibres";"ECM proteoglycans" XP_012238180.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003485479.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_003486929.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_024227382.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_012244905.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012242538.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012242277.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024227297.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_012238290.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003492643.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142 "Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins" XP_012236724.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003493155.2 4 MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_012247014.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012243742.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_024228102.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024221400.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity" XP_003494475.1 6 MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18 "Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism" XP_024220860.1 12 KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648 "Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Rho GTPase cycle";"Human cytomegalovirus infection";"G alpha (q) signalling events";"Thermogenesis";"Human papillomavirus infection";"NRAGE signals death through JNK" XP_024226840.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_024220663.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;MetaCyc: PWY-7511 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination" XP_024223791.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012249509.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012248998.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362300 "Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_003486590.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012244348.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_024220942.1 14 Reactome: R-HSA-399997;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-434316;KEGG: 04070+3.1.4.11;Reactome: R-HSA-500657;MetaCyc: PWY-7039;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-6367 "Acetylcholine regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidylinositol signaling system";"Presynaptic function of Kainate receptors";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism" XP_012246919.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_012250157.1 18 MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_003485721.1 10 Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-380972 "Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Carnitine metabolism";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_012244961.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_003493322.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003485118.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_003489324.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003490183.1 3 MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade" XP_024227308.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012237478.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_012246794.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_003494533.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012238213.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012248589.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_012247071.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012247698.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-8875555 "Downstream signal transduction";"MET receptor recycling";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1" XP_024223097.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_012248161.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012238350.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation" XP_003489391.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_024220477.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012247058.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_024223477.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003490918.2 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_003492630.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate" XP_024221225.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003494350.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_012248246.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012247304.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_003490614.2 5 Reactome: R-HSA-879415;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-8957275 "Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation" XP_003494790.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024228424.1 6 MetaCyc: PWY-6606;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-7442;Reactome: R-HSA-74259 "Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism" XP_024221657.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_012247344.1 13 KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5 "Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Propanoate metabolism" XP_024227326.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012240260.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199 "Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation" XP_024227008.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_012238689.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_003489862.1 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" XP_012236861.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_024220440.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012245124.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" XP_003484732.1 57 Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-450408 "Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"UCH proteinases";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_012244090.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003485309.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960 "BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC" XP_024225565.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_012237971.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_003493579.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_024220973.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_024221027.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_024223635.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_024225726.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012249757.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_012244166.1 10 Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"Inhibition of membrane repair";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity" XP_024220616.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_024224496.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012241946.2 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_024226537.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003494176.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012238065.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_012245703.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012244695.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_012240514.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_003487564.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_024228212.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012245033.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003485922.1 15 Reactome: R-HSA-9634285;Reactome: R-HSA-9665246;Reactome: R-HSA-9665244;Reactome: R-HSA-9664565;Reactome: R-HSA-9665251;Reactome: R-HSA-9665247;Reactome: R-HSA-9665250;Reactome: R-HSA-9652282;Reactome: R-HSA-1236382;Reactome: R-HSA-9665245;Reactome: R-HSA-9665249;Reactome: R-HSA-1227986;Reactome: R-HSA-5637810;Reactome: R-HSA-9665233;Reactome: R-HSA-8863795 "Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to AEE788";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to trastuzumab";"Downregulation of ERBB2 signaling" XP_012238039.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_024228473.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_024225948.1 13 Reactome: R-HSA-2160916;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" XP_024227470.1 12 MetaCyc: PWY-7385;Reactome: R-HSA-70263;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13 "1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Methane metabolism" XP_003488597.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_003487044.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024221941.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012249750.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024227926.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012246913.1 7 MetaCyc: PWY-7185;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00730+3.6.1.15;KEGG: 00230+3.6.1.15;MetaCyc: PWY-6545 "UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_012245528.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024228261.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_003493208.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_012242083.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012240088.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_012247299.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_024227603.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003487146.1 5 MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6 "Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism" XP_024222187.1 5 Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003485659.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863 "RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination" XP_012236418.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012242432.1 11 Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642 "Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling" XP_003491133.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012243469.1 7 KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7219;MetaCyc: PWY-7234 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III" XP_024220558.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024223437.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_024225550.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004 "Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity" XP_024221841.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_012247345.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_024226152.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003492219.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_012242338.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_024227483.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_003490896.1 7 Reactome: R-HSA-983170;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-381183;Reactome: R-HSA-3371453 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"IRE1alpha activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response" XP_024222457.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594 "Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events" XP_012249909.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003490955.3 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_012242463.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012245735.1 27 Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-5578749 "NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs" XP_012236445.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_003493342.1 11 MetaCyc: PWY-7102;MetaCyc: PWY-922;MetaCyc: PWY-5123;MetaCyc: PWY-7560;MetaCyc: PWY-6174;Reactome: R-HSA-191273;MetaCyc: PWY-6383;MetaCyc: PWY-7524;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6859;MetaCyc: PWY-7391 "Bisabolene biosynthesis (engineered)";"Mevalonate pathway I";"Trans, trans-farnesyl diphosphate biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"All-trans-farnesol biosynthesis";"Isoprene biosynthesis II (engineered)" XP_024221066.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012239912.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_012240602.1 13 KEGG: 00670+6.3.4.3;MetaCyc: PWY-2161;MetaCyc: PWY-1722;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9 "One carbon pool by folate";"Folate polyglutamylation";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"One carbon pool by folate" XP_012240301.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_003486853.1 11 KEGG: 04150+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"FOXO-mediated transcription of cell death genes";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_024220195.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003493705.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_003491115.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_012246869.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_024226146.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012239991.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_003490928.1 5 MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-191273 "Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis" XP_024224551.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_024228144.1 4 Reactome: R-HSA-8866427;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-9031525 "VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake" XP_012240824.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024226665.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_024225105.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_024226077.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_024227683.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012244713.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024223178.1 9 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_024226382.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003486608.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_012246540.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012241867.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024227543.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012243958.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_012249328.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)" XP_012242884.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003491171.1 7 KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7219;MetaCyc: PWY-7234 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III" XP_003484452.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_024220806.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012240775.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012240527.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_012244300.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003486117.1 10 Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692 "MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity" XP_003491278.1 8 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_003486641.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012244191.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_024226918.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012245176.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024221598.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012238347.1 15 Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-9603505;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"NTRK3 as a dependence receptor";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex" XP_003484707.1 6 Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-6898;MetaCyc: PWY-7356;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2 "Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism" XP_024225682.1 7 MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695 "Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Neutrophil degranulation" XP_003490519.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_012250045.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_024227703.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_012240308.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_003494079.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_012242155.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation" XP_003486523.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003488226.3 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024223129.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003490028.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003486560.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024222384.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_024228188.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_012240563.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003486681.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012246921.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_012236804.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_024222552.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024226596.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_003485311.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012247959.1 6 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;Reactome: R-HSA-163560 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism" XP_012246552.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003492449.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024224569.1 11 Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"RORA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)" XP_024226672.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_003491535.1 4 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_012244923.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012247937.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003486932.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012246824.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003491700.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024220475.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024224116.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012243856.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012237796.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558 "Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K Cascade";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_003491926.1 12 Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-73762;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-5250924;Reactome: R-HSA-9013508 "NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"RNA Polymerase I Transcription Initiation";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"NOTCH3 Intracellular Domain Regulates Transcription" XP_012248959.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_024227622.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012240562.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012243568.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003489877.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_012242675.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012248809.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_003490159.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012237771.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_012248025.1 3 KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis" XP_024221347.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024221016.1 11 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"FOXO-mediated transcription of cell death genes";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway" XP_012241507.1 33 Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-159230 "Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA" XP_003486803.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis" XP_012236423.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003492215.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_024221067.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012244669.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_012248253.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_012245942.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_012246197.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_024221568.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024228046.1 10 MetaCyc: PWY-6362;MetaCyc: PWY-6369;MetaCyc: PWY-6361;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6372 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)" XP_003494522.1 57 Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-349425 "Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"UCH proteinases";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1" XP_024223086.1 4 Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_012247215.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_012247037.1 14 KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;Reactome: R-HSA-75109;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4 "Glycerophospholipid metabolism";"Sphingolipid metabolism";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Synthesis of PE";"Synthesis of PC";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Glycerolipid metabolism" XP_003487540.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012236419.1 12 KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"mTOR signaling pathway";"G alpha (q) signalling events";"Human cytomegalovirus infection";"Thermogenesis";"NRAGE signals death through JNK";"Human papillomavirus infection" XP_024220207.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003491945.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_024225365.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_024228105.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024222713.1 5 MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7766;MetaCyc: PWY-7159 "3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_003489744.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_012244122.1 7 KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10 "Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis II";"Drug metabolism - other enzymes" XP_012246142.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_024226478.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012241195.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_003492920.1 24 Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-420092 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G-protein activation";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors" XP_003491902.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024227457.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_003484635.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_003494908.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_012239267.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_024222055.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_024220704.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024225056.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003491545.1 11 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_024224909.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_012237990.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359 "PKA activation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation" XP_024220460.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_024221555.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_012245926.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_012247004.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012245178.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_024220279.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation" XP_012247069.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012240689.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_012241038.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003493508.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003492491.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012245115.1 9 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection" XP_003489685.1 11 Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-6804114;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-2426168 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RORA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)" XP_012246416.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_024224379.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_024228401.1 13 Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5218921 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Ca2+ pathway";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation" XP_003493408.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_003490018.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_003486251.1 6 Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123 "Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I" XP_003494060.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003485813.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024220625.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012246195.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_003492100.2 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_012241441.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_003490579.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003491202.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_024227099.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024226778.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012249495.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_012239086.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012238216.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-1433559 "Neddylation";"Regulation of KIT signaling" XP_012241136.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012240382.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_003493016.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003487443.1 3 Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_024228007.1 8 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway" XP_003494726.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003485985.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_012243220.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_003487668.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_012245806.1 6 Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism" XP_012247175.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003486945.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_024224658.1 8 Reactome: R-HSA-442982;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244 "Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation" XP_012240780.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232 "Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_012242464.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012236428.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_003489450.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012243462.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024225728.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003489933.1 4 MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_012243164.2 12 Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001 "Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade" XP_012238755.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012239905.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012247270.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_024220651.1 3 MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_024228096.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024221182.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "G alpha (i) signalling events";"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_012240536.1 13 Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-5218920;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5628897 "Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes" XP_012237956.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_024226602.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_024222472.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012237570.1 6 Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368 "Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation" XP_003492542.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012246240.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_003491427.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_024227174.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_024222114.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003484618.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_012244929.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012249579.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024223609.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_024228080.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024227309.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012244529.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_012248513.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_024223789.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_012237976.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_024222666.1 16 Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176408 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase" XP_024226261.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_012241067.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_003488604.2 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_024228262.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription" XP_012244510.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012236991.1 8 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-5689880 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases" XP_024224626.1 3 KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740;MetaCyc: PWY-7999 "Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle" XP_003489880.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_012241446.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_024220801.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024226837.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012244962.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_024221208.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_003486359.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003489163.1 26 Reactome: R-HSA-8866654;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-1362277;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-4615885;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-6804114;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-5656121;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-174414;Reactome: R-HSA-69205;Reactome: R-HSA-5651801 "E3 ubiquitin ligases ubiquitinate target proteins";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of E2F targets under negative control by DREAM complex";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"SUMOylation of DNA replication proteins";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the C-strand of the telomere";"G1/S-Specific Transcription";"PCNA-Dependent Long Patch Base Excision Repair" XP_024226208.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_012239405.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_003490697.1 29 Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-5696400;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-167160 "RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"Dual Incision in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_012244932.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012242708.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012243600.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_012237750.1 8 KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_012244115.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003491014.2 6 Reactome: R-HSA-3656243;Reactome: R-HSA-2022857;Reactome: R-HSA-3000178;Reactome: R-HSA-2022854;Reactome: R-HSA-3656225;Reactome: R-HSA-3656244 "Defective ST3GAL3 causes MCT12 and EIEE15";"Keratan sulfate degradation";"ECM proteoglycans";"Keratan sulfate biosynthesis";"Defective CHST6 causes MCDC1";"Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)" XP_003493682.2 5 KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22 "Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism" XP_012236763.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003492913.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003484780.1 8 Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6;MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-5659996;Reactome: R-HSA-6791461;KEGG: 00710+5.3.1.6 "Pentose phosphate pathway";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"RPIA deficiency: failed conversion of R5P to RU5P";"RPIA deficiency: failed conversion of RU5P to R5P";"Carbon fixation in photosynthetic organisms" XP_003489261.1 10 KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-922;KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7524;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10 "Butanoate metabolism";"PPARA activates gene expression";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation" XP_024226812.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003486313.1 5 Reactome: R-HSA-936440;Reactome: R-HSA-6811555;Reactome: R-HSA-1169408;Reactome: R-HSA-6804756;Reactome: R-HSA-5668599 "Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation";"ISG15 antiviral mechanism";"Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate NADPH Oxidases" XP_012245632.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012237972.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003489349.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_003492540.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003488637.1 5 Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565 "Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_003492432.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003486536.3 7 MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862 "Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_012245683.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_003491331.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_024223030.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003493215.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012241348.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7036 "Juniperonate biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II" XP_003493198.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_012241086.1 11 Reactome: R-HSA-912694;Reactome: R-HSA-432142;Reactome: R-HSA-389948;Reactome: R-HSA-388841;Reactome: R-HSA-391160;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-877312;Reactome: R-HSA-210990;Reactome: R-HSA-9008059 "Regulation of IFNA signaling";"Platelet sensitization by LDL";"PD-1 signaling";"Costimulation by the CD28 family";"Signal regulatory protein family interactions";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"Regulation of IFNG signaling";"PECAM1 interactions";"Interleukin-37 signaling" XP_012249310.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681 "G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT" XP_003484752.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_003490324.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024220304.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_012240454.1 2 Reactome: R-HSA-192456;Reactome: R-HSA-975634 "Digestion of dietary lipid";"Retinoid metabolism and transport" XP_024226651.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_024221776.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_003485809.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_003485076.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_012242266.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_012248867.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_003484885.2 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_024224364.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_024221399.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_003488347.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_024225673.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_024225949.1 13 Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52 "CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Other glycan degradation";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_024227582.1 6 Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205 "TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_003492924.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion" XP_012245500.1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" XP_024222369.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012246788.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003494062.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_024222224.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012243784.1 8 Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5173105 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation" XP_012236979.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024225594.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_012245825.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012244784.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012240062.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012236626.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" XP_024222218.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_012245995.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012248697.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_012236429.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_003485741.1 20 MetaCyc: PWY-7288;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-6837;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340 "Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)" XP_024220566.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024225569.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport" XP_024224433.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012238431.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_003492331.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001 "NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade" XP_012237699.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation" XP_012239118.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_012236729.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_012245582.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_024227154.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012243857.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024225349.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_012239770.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_024220215.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024224492.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003485091.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012237051.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_024225786.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003485960.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024225877.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"Long-term potentiation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Trafficking of AMPA receptors" XP_024225869.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955 "RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Long-term potentiation";"RAF activation";"Ion homeostasis";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_012241581.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012241448.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_003493277.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_024225535.1 13 Reactome: R-HSA-1442490;Reactome: R-HSA-3000178;Reactome: R-HSA-2214320;Reactome: R-HSA-1474244;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-2243919;Reactome: R-HSA-186797;Reactome: R-HSA-419037;Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-3000157 "Collagen degradation";"ECM proteoglycans";"Anchoring fibril formation";"Extracellular matrix organization";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Crosslinking of collagen fibrils";"Signaling by PDGF";"NCAM1 interactions";"Integrin cell surface interactions";"Collagen chain trimerization";"Laminin interactions" XP_012236965.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_024226179.1 27 Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-5619107 "SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_003486033.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_003490019.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012244242.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_012247924.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012245676.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_012236733.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_003487971.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_003490521.1 3 Reactome: R-HSA-420029;Reactome: R-HSA-4608870;Reactome: R-HSA-2173791 "Tight junction interactions";"Asymmetric localization of PCP proteins";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)" XP_012247090.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003493699.1 7 Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277 "Cyclin D associated events in G1";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex" XP_024220722.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_012247287.1 10 MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13 "Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism" XP_024221944.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024227311.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_003492222.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024227814.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_024225787.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012246704.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012238804.1 3 Reactome: R-HSA-5362798;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_012239573.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012238528.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012247322.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_012240363.1 10 Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590 "Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling" XP_012248897.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins" XP_012237686.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012237855.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003488526.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" XP_012246236.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_012244091.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012242907.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012244005.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003484631.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003485706.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_012239790.1 10 MetaCyc: PWY-5849;MetaCyc: PWY-5839;MetaCyc: PWY-5892;MetaCyc: PWY-5895;MetaCyc: PWY-5844;MetaCyc: PWY-5891;KEGG: 00130+2.1.1.163;Reactome: R-HSA-2142789;MetaCyc: PWY-7996;MetaCyc: PWY-5890 "Menaquinol-6 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-11 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-10 biosynthesis" XP_024225276.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_024223219.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024220443.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012249854.1 9 KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-6703;MetaCyc: PWY-6147;MetaCyc: PWY-7852 "Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)" XP_024226073.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024225666.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_024227385.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003492658.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003488517.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_024226932.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024227276.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012248977.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5578749 "Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs" XP_003484850.1 5 MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668 "Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_012247463.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012238598.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_024221398.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_012243758.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_024228358.1 4 Reactome: R-HSA-4420097;Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-373753 "VEGFA-VEGFR2 Pathway";"Activation of RAC1";"Downstream signal transduction";"Nephrin family interactions" XP_012250483.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_024223880.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_024224498.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003491397.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012241702.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_003486645.1 8 KEGG: 00790+1.14.16.2;KEGG: 00350+1.14.16.2;Reactome: R-HSA-209905;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5394;MetaCyc: PWY-6133;MetaCyc: PWY-3581;MetaCyc: PWY-5049 "Folate biosynthesis";"Tyrosine metabolism";"Catecholamine biosynthesis";"Isoquinoline alkaloid biosynthesis";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis II";"(S)-reticuline biosynthesis I";"Rosmarinic acid biosynthesis II" XP_012240649.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_003485300.1 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724 "Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription" XP_012240972.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins" XP_012243885.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_012243783.1 8 Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5173105 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation" XP_012249636.1 20 MetaCyc: PWY-7007;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;Reactome: R-HSA-9033241 "Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import" XP_024224387.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_003494007.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024224625.1 3 KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors" XP_003485077.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_003494372.1 5 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Purine metabolism";"Thiamine metabolism" XP_024222663.1 26 Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"MHC class II antigen presentation";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic" XP_003490986.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_003489359.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_003490329.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012237409.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_003488198.1 11 Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-72163;Reactome: R-HSA-350054;Reactome: R-HSA-1912408 "RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation" XP_003494666.1 3 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA" XP_003487020.1 22 MetaCyc: PWY-6433;MetaCyc: PWY-7727;MetaCyc: PWY-5353;MetaCyc: PWY-7053;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7049;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7728 "Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)" XP_024223577.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012236732.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_012243324.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_003487129.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_024222190.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_024220672.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_012238815.1 5 Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "Chromatin modifying enzymes";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012245440.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_024228404.1 4 MetaCyc: PWY-5041;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581 "S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation" XP_003494093.1 3 KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336 "Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_024226458.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_003486236.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_024222561.1 8 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Activation of RAC1";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_012239335.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_012242934.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024220300.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_012237480.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_024226667.1 3 Reactome: R-HSA-4086398;Reactome: R-HSA-392517;Reactome: R-HSA-418457 "Ca2+ pathway";"Rap1 signalling";"cGMP effects" XP_003492117.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003492991.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012241055.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003485409.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_003492441.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987 "Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis" XP_012241392.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_024226147.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_012245099.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012243500.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_003490343.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_024224381.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_012240505.1 17 MetaCyc: PWY-7179;MetaCyc: PWY-6608;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179-1;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-6611;MetaCyc: PWY-5532;MetaCyc: PWY-5695;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6620;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1 "Purine deoxyribonucleosides degradation I";"Guanosine nucleotides degradation III";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II";"Purine catabolism";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Purine salvage";"Neutrophil degranulation";"Guanine and guanosine salvage";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism" XP_012247319.1 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_024221945.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012236523.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024221465.1 9 Reactome: R-HSA-112043;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204 "PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol" XP_012238938.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_024226461.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012244528.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_012238130.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_024221119.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003487551.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_024224189.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012243962.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_003485308.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-141430 "Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_024228098.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012248603.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_024220907.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_012243001.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012248389.1 7 KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-6363 "Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_024222441.1 5 MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954 "Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)" XP_024220608.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_012238767.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_003488293.2 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_024222339.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing" XP_024225716.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012246712.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003486845.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_003492433.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012241999.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_024220536.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003487934.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_003492293.1 7 KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2 "Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism" XP_012236134.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_012247601.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012248327.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012242858.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_024220529.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024228238.1 12 Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-429947 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Deadenylation of mRNA" XP_024223383.1 7 MetaCyc: PWY-6122;Reactome: R-HSA-73817;Reactome: R-HSA-196780;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+6.3.4.13 "5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Biotin transport and metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism" XP_024225583.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012241334.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012249848.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_003494065.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_003484410.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_024222381.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_012238059.1 6 MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_012243624.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_024227842.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012242113.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence" XP_012239673.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_012242680.1 26 Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-8866907;Reactome: R-HSA-1234158;Reactome: R-HSA-5621575;Reactome: R-HSA-3371568;Reactome: R-HSA-3899300;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-918233;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-9614657 "NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression by Hypoxia-inducible Factor";"CD209 (DC-SIGN) signaling";"Attenuation phase";"SUMOylation of transcription cofactors";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes" XP_012249704.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_012243004.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012248707.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_003485719.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024221539.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_012248698.2 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_024222867.1 8 Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750 "SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6" XP_012246882.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_003493969.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_024226745.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_003494949.1 4 Reactome: R-HSA-947581;MetaCyc: PWY-6823;MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis" XP_024228328.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012237301.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_024226341.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_024220910.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_003486477.1 9 Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-438066;Reactome: R-HSA-6794361;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932 "Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Neurexins and neuroligins";"Long-term potentiation";"Synaptic adhesion-like molecules" XP_012244600.1 10 KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Regulation of TNFR1 signaling";"mTOR signaling pathway";"Thermogenesis";"TNFR1-induced NFkappaB signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"T cell receptor signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_024222658.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012239890.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012249103.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_012242707.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003484939.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024223707.1 57 Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-75815 "Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D" XP_024222394.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012242128.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_003486942.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003494319.2 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003487598.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003493378.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_024221073.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_003487612.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_024227684.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_024223683.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024221811.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_003485241.1 2 MetaCyc: PWY-8061;Reactome: R-HSA-2393930 "8-oxo-(d)GTP detoxification II";"Phosphate bond hydrolysis by NUDT proteins" XP_003484463.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003485236.1 4 Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211 "ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes" XP_012246232.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012249734.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling" XP_012243895.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003492479.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_003487148.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_012237749.1 8 KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1 "Streptomycin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism" XP_024223558.1 33 Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885 "Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"SUMOylation of DNA replication proteins" XP_024227103.1 3 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_024221136.1 6 MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis" XP_012247267.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_024227477.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024223867.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_003487042.1 8 KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481 "Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate" XP_003485377.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_003484772.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_024222849.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_003493168.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024223744.1 8 Reactome: R-HSA-5173105;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;Reactome: R-HSA-5083633 "O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_003490421.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_024228286.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_012239024.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_012246850.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_024226131.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024220413.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012247185.1 14 Reactome: R-HSA-205043;Reactome: R-HSA-6798695;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-1474228;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-9013507 "NRIF signals cell death from the nucleus";"Neutrophil degranulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"Degradation of the extracellular matrix";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_003491255.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024224677.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012238051.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024220843.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" XP_012249205.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012246996.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012236433.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol" XP_012249151.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_024224967.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" XP_012244908.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003494906.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_003488280.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012240419.1 5 Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012249247.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_012249778.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024226811.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_003489332.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_024228296.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_003491862.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_024227471.1 12 KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13 "Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis" XP_024224815.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012240887.1 3 Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193 "Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_024225357.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_003489258.1 3 Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722 "Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" XP_012236443.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_024220659.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012248493.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012240817.1 3 Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166 "Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2" XP_003493618.1 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_003489341.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_003487405.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_003490068.1 19 Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-8964038 "Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Chylomicron assembly";"VLDL assembly";"Scavenging by Class F Receptors";"LDL remodeling";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL clearance" XP_003493348.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_024225082.1 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism" XP_024221710.1 7 MetaCyc: PWY-7282;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism" XP_003492981.1 4 MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate" XP_024226023.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012243251.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_024225858.1 5 MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism" XP_024227016.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_024224530.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012244329.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012242514.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_012238759.1 11 Reactome: R-HSA-69231;Reactome: R-HSA-5693565;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-525793 "Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Myogenesis" XP_024228131.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_012238790.1 7 Reactome: R-HSA-351202;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16 "Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_003484495.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_012248181.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012236289.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_012238351.2 3 Reactome: R-HSA-70350;Reactome: R-HSA-168928;Reactome: R-HSA-9639288 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Amino acids regulate mTORC1" XP_003486416.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_024221087.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_012236897.1 3 KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis" XP_003486092.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003486089.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_024226630.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_012245663.1 19 Reactome: R-HSA-4420097;Reactome: R-HSA-389359;Reactome: R-HSA-194840;Reactome: R-HSA-5626467;Reactome: R-HSA-182971;Reactome: R-HSA-428543;Reactome: R-HSA-5687128;Reactome: R-HSA-2029482;Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-525793;Reactome: R-HSA-5627123;Reactome: R-HSA-8950505;Reactome: R-HSA-983231;Reactome: R-HSA-114604 "VEGFA-VEGFR2 Pathway";"CD28 dependent Vav1 pathway";"Rho GTPase cycle";"RHO GTPases activate IQGAPs";"EGFR downregulation";"Inactivation of CDC42 and RAC1";"MAPK6/MAPK4 signaling";"Regulation of actin dynamics for phagocytic cup formation";"DCC mediated attractive signaling";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"Myogenesis";"RHO GTPases activate PAKs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade" XP_024227037.1 9 Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946 "Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Neutrophil degranulation";"Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants" XP_024222225.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_012241538.1 14 Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "HDR through Homologous Recombination (HRR)";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1" XP_003493763.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012236502.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_003492537.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_024225337.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_012240516.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_003488291.1 3 Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999 "Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle" XP_012239842.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003488480.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_024224338.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012243618.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-166208 "Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling" XP_024220588.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_012241779.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_012237723.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024225882.1 19 Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-936837 "RAF activation";"Ion homeostasis";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases" XP_003488095.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-159236 "tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_024226063.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024220445.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012244520.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_012236967.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_003487846.1 33 Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-165054 "SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"RHO GTPases Activate Formins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA" XP_024224051.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012247996.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024222089.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_024223899.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_003488569.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_024227439.1 12 KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4 "Sulfur metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Monobactam biosynthesis";"Purine metabolism";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Assimilatory sulfate reduction III";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Purine metabolism" XP_024222675.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_003485027.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_012239160.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_003492268.1 12 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4" XP_012247745.2 6 MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_024223342.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012245110.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_012240101.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_024228239.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_024222219.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_003484842.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012237260.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane" XP_024224545.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003489413.1 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_024220397.1 7 MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol" XP_024228366.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_024222712.1 5 MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;MetaCyc: PWY-5531 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)" XP_003491464.1 52 Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553 "Vpu mediated degradation of CD4";"Degradation of AXIN";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"UCH proteinases";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs" XP_003491630.1 7 Reactome: R-HSA-71336;MetaCyc: PWY-6855;MetaCyc: PWY-6906;MetaCyc: PWY-8004;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;KEGG: 00030+3.1.1.31 "Pentose phosphate pathway";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Entner-Doudoroff pathway I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway" XP_003485511.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_024228120.1 5 KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;Reactome: R-HSA-389661;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88 "Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism" XP_003492588.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_012236207.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012250331.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003491832.2 3 Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_024222965.1 6 Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;MetaCyc: PWY-6317 "Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)" XP_012238304.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_003488774.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" XP_003491413.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012246026.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024226908.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_024223852.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012242909.1 4 Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48 "Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes" XP_012239839.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_012239270.1 10 MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-7344 "Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis" XP_012247409.1 3 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_024224849.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_003486950.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2" XP_003489639.1 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_012248921.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756 "G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation" XP_012238023.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_003491366.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69091 "Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching" XP_024226157.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024226934.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003484416.1 8 Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841 "SUMOylation of chromatin organization proteins";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines" XP_024221379.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_003485321.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003485012.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024226905.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024227408.1 5 MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841;Reactome: R-HSA-196757 "Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations II (plants)";"Metabolism of folate and pterines" XP_003488398.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003485725.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_024222245.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_024220205.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012247172.1 17 MetaCyc: PWY-6679;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780;Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-163765;Reactome: R-HSA-2426168 "Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Propanoate metabolism";"Glyoxylate assimilation";"Biotin transport and metabolism";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)" XP_024223592.1 11 Reactome: R-HSA-6804114;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400206 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha" XP_003493043.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024225442.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_003493513.1 5 MetaCyc: PWY-6892;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7 "Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism" XP_024220799.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_012239465.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_012247355.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012237430.1 18 MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7227;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7205;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_003494209.2 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_024224947.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_024223427.1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA" XP_012241241.2 57 Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-9010553 "Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs" XP_012236721.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_012244239.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_024224831.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003490228.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_003486312.1 5 Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722 "PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex" XP_012248702.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_024228092.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003486052.2 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012250111.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_003489530.1 7 MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716 "Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_012238814.1 11 MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-2029485;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8052 "Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Role of phospholipids in phagocytosis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis" XP_012250152.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_012242753.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_024224263.1 6 Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape" XP_012239162.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_003492581.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024224752.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_024227366.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_024227851.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_012241636.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_012239333.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003492995.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_003489253.1 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" XP_012243053.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_003486328.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012237145.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_003490259.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_012244926.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662 "Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"EPHB-mediated forward signaling" XP_012241177.1 11 Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-174430;Reactome: R-HSA-5685942 "Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)" XP_024222518.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012239916.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_012244292.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_012237188.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_003489052.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-180024 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events" XP_012241087.1 11 Reactome: R-HSA-114604;Reactome: R-HSA-877312;Reactome: R-HSA-210990;Reactome: R-HSA-9008059;Reactome: R-HSA-389948;Reactome: R-HSA-432142;Reactome: R-HSA-912694;Reactome: R-HSA-388841;Reactome: R-HSA-512988;Reactome: R-HSA-909733;Reactome: R-HSA-391160 "GPVI-mediated activation cascade";"Regulation of IFNG signaling";"PECAM1 interactions";"Interleukin-37 signaling";"PD-1 signaling";"Platelet sensitization by LDL";"Regulation of IFNA signaling";"Costimulation by the CD28 family";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interferon alpha/beta signaling";"Signal regulatory protein family interactions" XP_003492651.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_024220467.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003487121.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_024227645.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_003487539.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003485185.2 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_012250195.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_012246909.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003492565.1 13 MetaCyc: PWY-6370;MetaCyc: PWY-2261;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-7533;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1 "Ascorbate recycling (cytosolic)";"Ascorbate glutathione cycle";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Drug metabolism - other enzymes";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Ascorbate and aldarate metabolism" XP_003490038.1 24 Reactome: R-HSA-983231;Reactome: R-HSA-5610783;Reactome: R-HSA-163560;Reactome: R-HSA-392517;Reactome: R-HSA-5621575;Reactome: R-HSA-5610785;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-163358;Reactome: R-HSA-9634600;Reactome: R-HSA-5610780;KEGG: 04150+2.7.11.11;Reactome: R-HSA-442720;Reactome: R-HSA-9010642;Reactome: R-HSA-164378;Reactome: R-HSA-4420097;Reactome: R-HSA-163615;Reactome: R-HSA-111931;Reactome: R-HSA-180024;Reactome: R-HSA-8963896;Reactome: R-HSA-8853659;Reactome: R-HSA-5687128;Reactome: R-HSA-422356 "Factors involved in megakaryocyte development and platelet production";"Degradation of GLI2 by the proteasome";"Triglyceride catabolism";"Rap1 signalling";"CD209 (DC-SIGN) signaling";"GLI3 is processed to GLI3R by the proteasome";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA-mediated phosphorylation of key metabolic factors";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Degradation of GLI1 by the proteasome";"mTOR signaling pathway";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"ROBO receptors bind AKAP5";"PKA activation in glucagon signalling";"VEGFA-VEGFR2 Pathway";"PKA activation";"PKA-mediated phosphorylation of CREB";"DARPP-32 events";"HDL assembly";"RET signaling";"MAPK6/MAPK4 signaling";"Regulation of insulin secretion" XP_024220796.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_024226876.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_024224048.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024223729.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012245369.1 2 Reactome: R-HSA-2173796;Reactome: R-HSA-6785807 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interleukin-4 and Interleukin-13 signaling" XP_003489278.3 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012243216.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003491239.1 4 MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7807 "(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Pyrophosphate hydrolysis";"Glyphosate degradation III" XP_012246718.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024226891.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012246264.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_024225857.1 5 KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013;Reactome: R-HSA-446210 "Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine" XP_024225679.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024223563.1 33 Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-180746 "Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"HCMV Early Events";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Nuclear import of Rev protein" XP_003493894.1 2 Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" XP_012243575.1 9 Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3656535;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-3645790;Reactome: R-HSA-3304356 "TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"TGFBR2 Kinase Domain Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_024225784.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012239186.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003492521.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003493712.1 7 Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517 "Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid" XP_012248243.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003484425.1 56 Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-9020702 "TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling" XP_012238164.1 16 Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-182218;Reactome: R-HSA-196025;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-164939;Reactome: R-HSA-416993;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-177504 "WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Formation of annular gap junctions";"Recycling pathway of L1";"LDL clearance";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Nef mediated downregulation of CD28 cell surface expression";"Trafficking of GluR2-containing AMPA receptors";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling" XP_024225609.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171 "ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions" XP_012245808.1 6 MetaCyc: PWY-6987;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15 "Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism" XP_003485870.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_012246932.1 13 Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8866427 "Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"VLDLR internalisation and degradation" XP_003494463.1 4 MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20 "Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism" XP_012246725.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003491374.1 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" XP_024225779.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012248187.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024227889.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72702 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition" XP_024225506.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003484851.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012238514.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024225097.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_024224493.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_024221931.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_024224315.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_012243841.2 4 Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494 "Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV" XP_012247800.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_024225244.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012250082.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012239028.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012249663.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_003493630.1 13 KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5392 "Propanoate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II" XP_012249978.1 7 Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_012241072.1 4 Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_012245488.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012239787.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_012242290.1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_012244647.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_024223482.1 11 Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801 "Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair" XP_003487843.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation" XP_012243780.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" XP_012240372.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024221356.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_003487967.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012240854.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_003492177.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_024225170.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012247940.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_012246731.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012244965.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_012250098.1 7 Reactome: R-HSA-4641258;Reactome: R-HSA-201681;Reactome: R-HSA-5368598;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-201688;Reactome: R-HSA-4086400 "Degradation of DVL";"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"WNT mediated activation of DVL";"PCP/CE pathway" XP_003487367.1 5 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)" XP_003486347.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_024220636.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_012243603.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_012245763.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024221971.1 4 KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9 "Propanoate metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism" XP_012242888.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_024223298.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_003492168.1 42 Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5693571;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638;Reactome: R-HSA-69473;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-110331;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-5625886;Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-5693607;Reactome: R-HSA-8936459;Reactome: R-HSA-5334118;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-110328;Reactome: R-HSA-5250924;Reactome: R-HSA-1221632;Reactome: R-HSA-977225;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408 "DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Nonhomologous End-Joining (NHEJ)";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins";"G2/M DNA damage checkpoint";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged purine";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HCMV Late Events";"Cleavage of the damaged pyrimidine";"Processing of DNA double-strand break ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"DNA methylation";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"B-WICH complex positively regulates rRNA expression";"Meiotic synapsis";"Amyloid fiber formation";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation" XP_012240661.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_012239540.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_012241789.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway" XP_003492662.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012246918.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_012244240.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_003490874.2 15 Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176412 "Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Phosphorylation of the APC/C" XP_003484716.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012245043.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012240700.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_012238862.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Justicidin B biosynthesis" XP_012248085.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003494605.1 3 KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism" XP_003488470.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_012236633.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_012239749.1 26 Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Gap junction assembly";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic" XP_012245584.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_024226649.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_024223972.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_003488802.1 37 Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-983170;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-204005;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-9639288;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-4551638 "Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"MHC class II antigen presentation";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"HCMV Early Events";"COPII-mediated vesicle transport";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Amino acids regulate mTORC1";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins" XP_003493221.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012249519.1 27 Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-180746 "Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein" XP_024228008.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012244705.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012242458.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012241222.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_003493323.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state" XP_012245247.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-438066 "Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Trafficking of AMPA receptors";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation" XP_012241401.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_024226860.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740 "Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs" XP_024228065.1 4 Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594 "TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events" XP_012237279.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003492272.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_003489418.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003493567.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012240699.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_003484611.1 3 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_024224335.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012249832.2 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_012239544.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208 "mTOR signalling";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling" XP_003489743.1 3 Reactome: R-HSA-8964058;Reactome: R-HSA-1369062;Reactome: R-HSA-9029569 "HDL remodeling";"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_003485408.1 11 Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation" XP_024226102.1 5 MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681 "Protein ubiquitination";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT" XP_012248088.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012238237.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69091 "Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching" XP_024227045.1 19 MetaCyc: PWY-7338;MetaCyc: PWY-7007;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6 "10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism" XP_024224255.1 7 Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2122948 "Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_012239860.1 12 Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-167243 "Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery" XP_024225856.1 5 Reactome: R-HSA-446210;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16 "Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism" XP_003493354.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012241803.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_024226222.1 9 Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-3656535;Reactome: R-HSA-3304356;Reactome: R-HSA-3645790;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"UCH proteinases" XP_024228074.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_012241634.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_012246696.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_024226351.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003487563.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_024227648.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_024227410.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_024223517.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_024227738.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_024226144.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_024227379.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_024224659.1 8 Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324 "Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_024226803.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024222944.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_024227384.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_024223270.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024228461.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024226674.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_012248474.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_012237072.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003488777.2 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_012248127.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_012246855.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_024228107.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_024220664.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;MetaCyc: PWY-7511 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination" XP_003488040.2 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_012236508.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_012247810.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_024224741.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003492485.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_024227550.1 6 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock" XP_003488087.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-5466 "Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Matairesinol biosynthesis" XP_024226013.1 2 KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_003492107.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012244702.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_012243366.2 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_024224965.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" XP_003484616.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781 "Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression" XP_003491321.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_024220435.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_024227458.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_003488676.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_024220674.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024227935.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-5660862 "Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)" XP_012240847.1 11 Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685942 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)" XP_012236415.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012247026.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012249196.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_024224642.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012246853.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_003484998.1 17 Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6796648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6783310;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371453 "Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"mTOR signaling pathway";"Thermogenesis";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Human papillomavirus infection";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Relaxin signaling pathway";"Fanconi Anemia Pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Human immunodeficiency virus 1 infection";"Regulation of HSF1-mediated heat shock response" XP_003489793.2 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_012236111.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003491691.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012240116.1 16 Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176408 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase" XP_003487791.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation" XP_003493397.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_012249367.1 4 MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-5737 "L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis" XP_003493391.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_003486729.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012241616.1 4 KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation" XP_024225507.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024228083.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_024226061.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024223608.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_012237243.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_024225219.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_003492911.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_003489810.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_024226974.1 8 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_012250183.1 5 Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580 "FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence" XP_024220652.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_003485522.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_003488041.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_024220449.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003493768.2 4 Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_012239254.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024220832.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012247434.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_012247162.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_003485963.2 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_024225875.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952 "Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"RAF activation";"Long-term potentiation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions" XP_024222277.1 10 MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8053 "Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II" XP_003488068.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012241984.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012242749.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231 "Growth hormone receptor signaling";"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production" XP_024222893.1 6 Reactome: R-HSA-5632987;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606 "Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_012240932.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_012249333.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003485828.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012248019.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012240496.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_003491100.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_024226065.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_003494897.2 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_024226195.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_003487481.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_012246272.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_003489188.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012245920.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_012248442.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003487273.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_012250200.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_012249660.1 9 MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061 "4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Glutathione-mediated detoxification I" XP_003487577.1 17 Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_003488627.1 4 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;Reactome: R-HSA-72731 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP" XP_012237439.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_012247186.1 14 Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-1474228;Reactome: R-HSA-977225 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Degradation of the extracellular matrix";"Amyloid fiber formation" XP_024222184.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_003493541.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012240629.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003486586.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-5689880 "Ovarian tumor domain proteases";"Ub-specific processing proteases" XP_012236863.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_003492881.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012242513.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_012238780.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_003486288.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_024220389.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_003491390.1 7 KEGG: 00100+1.3.1.70;Reactome: R-HSA-191273;Reactome: R-HSA-9022692;MetaCyc: PWY-6074;MetaCyc: PWY-7154;MetaCyc: PWY-2541;MetaCyc: PWY-8026 "Steroid biosynthesis";"Cholesterol biosynthesis";"Regulation of MECP2 expression and activity";"Zymosterol biosynthesis";"Ergosterol biosynthesis II";"Phytosterol biosynthesis (plants)";"Sterol biosynthesis (methylotrophs)" XP_024220926.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_024225883.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244 "Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Trafficking of AMPA receptors";"RAF activation";"Long-term potentiation" XP_003490121.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_012242861.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_012243059.1 9 Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-416482;Reactome: R-HSA-114604;Reactome: R-HSA-2871809 "NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"FCERI mediated MAPK activation";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events";"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization" XP_012241082.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK" XP_003488483.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_012238786.1 7 KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16 "Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism" XP_012241311.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-418597 "Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events" XP_024225243.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_024227435.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-69481 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"UCH proteinases";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints" XP_012244989.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_012244689.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase" XP_012237447.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_024225889.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-3371571 "Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Long-term potentiation";"RAF activation";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation" XP_003487266.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024225641.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012236740.1 179 Reactome: R-HSA-187577;Reactome: R-HSA-3134975;Reactome: R-HSA-6804760;Reactome: R-HSA-2173791;Reactome: R-HSA-5654726;Reactome: R-HSA-168928;Reactome: R-HSA-2691232;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-9636383;Reactome: R-HSA-5689877;Reactome: R-HSA-9013507;Reactome: R-HSA-5656169;Reactome: R-HSA-912631;Reactome: R-HSA-69017;Reactome: R-HSA-2559585;Reactome: R-HSA-110312;Reactome: R-HSA-5654732;Reactome: R-HSA-162588;Reactome: R-HSA-6791226;Reactome: R-HSA-6783310;Reactome: R-HSA-9615710;Reactome: R-HSA-6781827;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-349425;Reactome: R-HSA-2408557;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-9637628;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-8866654;Reactome: R-HSA-4641257;Reactome: R-HSA-5610780;Reactome: R-HSA-5654733;Reactome: R-HSA-156827;Reactome: R-HSA-5693607;Reactome: R-HSA-68827;Reactome: R-HSA-9613829;Reactome: R-HSA-5610785;Reactome: R-HSA-156902;Reactome: R-HSA-1236382;Reactome: R-HSA-5655862;Reactome: R-HSA-1234176;Reactome: R-HSA-5357905;Reactome: R-HSA-9010553;Reactome: R-HSA-175474;Reactome: R-HSA-5693565;Reactome: R-HSA-975163;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-1295596;Reactome: R-HSA-5675482;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-6782210;Reactome: R-HSA-8856825;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-5607761;Reactome: R-HSA-6804757;Reactome: R-HSA-2173788;Reactome: R-HSA-450321;Reactome: R-HSA-8876493;Reactome: R-HSA-5684264;Reactome: R-HSA-201681;Reactome: R-HSA-5205685;Reactome: R-HSA-1169408;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-901032;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-110314;Reactome: R-HSA-8866652;Reactome: R-HSA-2565942;Reactome: R-HSA-9014325;Reactome: R-HSA-936440;Reactome: R-HSA-5696394;Reactome: R-HSA-5689880;Reactome: R-HSA-174048;Reactome: R-HSA-72689;Reactome: R-HSA-5689896;Reactome: R-HSA-2979096;Reactome: R-HSA-9645460;Reactome: R-HSA-5654727;Reactome: R-HSA-975957;Reactome: R-HSA-179409;Reactome: R-HSA-8875360;Reactome: R-HSA-5362768;Reactome: R-HSA-5689901;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-9033241;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5696395;Reactome: R-HSA-2559580;Reactome: R-HSA-2173796;Reactome: R-HSA-68949;Reactome: R-HSA-8849469;Reactome: R-HSA-9633012;Reactome: R-HSA-400253;Reactome: R-HSA-9013973;Reactome: R-HSA-532668;Reactome: R-HSA-174490;Reactome: R-HSA-2672351;Reactome: R-HSA-195253;Reactome: R-HSA-1358803;Reactome: R-HSA-8939902;Reactome: R-HSA-1253288;Reactome: R-HSA-5658442;Reactome: R-HSA-5675221;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-936964;Reactome: R-HSA-2122948;Reactome: R-HSA-69541;Reactome: R-HSA-205043;Reactome: R-HSA-5696400;Reactome: R-HSA-3785653;Reactome: R-HSA-168927;Reactome: R-HSA-3322077;Reactome: R-HSA-168638;Reactome: R-HSA-977225;Reactome: R-HSA-382556;Reactome: R-HSA-2122947;Reactome: R-HSA-2559582;Reactome: R-HSA-180534;Reactome: R-HSA-975144;Reactome: R-HSA-72706;Reactome: R-HSA-5685942;Reactome: R-HSA-209543;Reactome: R-HSA-9646399;Reactome: R-HSA-209560;Reactome: R-HSA-8856828;Reactome: R-HSA-6804756;Reactome: R-HSA-5607764;Reactome: R-HSA-6781823;Reactome: R-HSA-937039;Reactome: R-HSA-3769402;Reactome: R-HSA-975956;Reactome: R-HSA-8854050;Reactome: R-HSA-4641263;Reactome: R-HSA-8863795;Reactome: R-HSA-2644606;Reactome: R-HSA-937072;Reactome: R-HSA-75815;Reactome: R-HSA-69231;Reactome: R-HSA-1799339;Reactome: R-HSA-450408;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5656121;Reactome: R-HSA-9604323;Reactome: R-HSA-5357956;Reactome: R-HSA-975110;Reactome: R-HSA-2894862;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-445989;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-937041;Reactome: R-HSA-917729;Reactome: R-HSA-182971;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-917937;Reactome: R-HSA-8852276;Reactome: R-HSA-6807004;Reactome: R-HSA-69481;Reactome: R-HSA-2173795;Reactome: R-HSA-180585 "SCF(Skp2)-mediated degradation of p27/p21";"Regulation of innate immune responses to cytosolic DNA";"Regulation of TP53 Activity through Methylation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Negative regulation of FGFR1 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"Prevention of phagosomal-lysosomal fusion";"Josephin domain DUBs";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Termination of translesion DNA synthesis";"Regulation of signaling by CBL";"CDK-mediated phosphorylation and removal of Cdc6";"Oncogene Induced Senescence";"Translesion synthesis by REV1";"Negative regulation of FGFR3 signaling";"Budding and maturation of HIV virion";"Major pathway of rRNA processing in the nucleolus and cytosol";"Fanconi Anemia Pathway";"Late endosomal microautophagy";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Autodegradation of the E3 ubiquitin ligase COP1";"Selenocysteine synthesis";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"Modulation by Mtb of host immune system";"Dual incision in TC-NER";"Regulation of PTEN localization";"E3 ubiquitin ligases ubiquitinate target proteins";"Degradation of AXIN";"Degradation of GLI1 by the proteasome";"Negative regulation of FGFR4 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Processing of DNA double-strand break ends";"CDT1 association with the CDC6:ORC:origin complex";"Chaperone Mediated Autophagy";"GLI3 is processed to GLI3R by the proteasome";"Peptide chain elongation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Translesion synthesis by POLK";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of TNFR1 signaling";"Regulation of expression of SLITs and ROBOs";"Assembly Of The HIV Virion";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Spry regulation of FGF signaling";"Regulation of necroptotic cell death";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cargo recognition for clathrin-mediated endocytosis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of TP53 Degradation";"Downregulation of TGF-beta receptor signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"InlA-mediated entry of Listeria monocytogenes into host cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TCF dependent signaling in response to WNT";"Pink/Parkin Mediated Mitophagy";"ISG15 antiviral mechanism";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER Quality Control Compartment (ERQC)";"Neddylation";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Recognition of DNA damage by PCNA-containing replication complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PLK1 Activity at G2/M Transition";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Negative regulators of DDX58/IFIH1 signaling";"DNA Damage Recognition in GG-NER";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Cyclin B";"Formation of a pool of free 40S subunits";"Ovarian tumor domain proteases";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Alpha-protein kinase 1 signaling pathway";"Negative regulation of FGFR2 signaling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"APC-Cdc20 mediated degradation of Nek2A";"InlB-mediated entry of Listeria monocytogenes into host cell";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Metalloprotease DUBs";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Peroxisomal protein import";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Formation of Incision Complex in GG-NER";"Oxidative Stress Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Orc1 removal from chromatin";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Circadian Clock";"TICAM1-dependent activation of IRF3/IRF7";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Membrane binding and targetting of GAG proteins";"Stimuli-sensing channels";"Degradation of beta-catenin by the destruction complex";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB4 signaling";"Regulation of RAS by GAPs";"Negative regulation of MAPK pathway";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Activated NOTCH1 Transmits Signal to the Nucleus";"Stabilization of p53";"NRIF signals cell death from the nucleus";"Dual Incision in GG-NER";"Myoclonic epilepsy of Lafora";"TICAM1, RIP1-mediated IKK complex recruitment";"Glycogen synthesis";"NOD1/2 Signaling Pathway";"Amyloid fiber formation";"ABC-family proteins mediated transport";"NOTCH1 Intracellular Domain Regulates Transcription";"Senescence-Associated Secretory Phenotype (SASP)";"Vpu mediated degradation of CD4";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"HDR through Homologous Recombination (HRR)";"p75NTR recruits signalling complexes";"Aggrephagy";"NF-kB is activated and signals survival";"Clathrin-mediated endocytosis";"Regulation of TP53 Activity through Phosphorylation";"CLEC7A (Dectin-1) signaling";"Formation of TC-NER Pre-Incision Complex";"IRAK1 recruits IKK complex";"Deactivation of the beta-catenin transactivating complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of FZD by ubiquitination";"Downregulation of ERBB2 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Ubiquitin-dependent degradation of Cyclin D";"Cyclin D associated events in G1";"SRP-dependent cotranslational protein targeting to membrane";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"UCH proteinases";"Translesion synthesis by POLI";"Negative regulation of NOTCH4 signaling";"TNFR1-induced NFkappaB signaling pathway";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"IKK complex recruitment mediated by RIP1";"Endosomal Sorting Complex Required For Transport (ESCRT)";"EGFR downregulation";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Iron uptake and transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of MET activity";"G2/M Checkpoints";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Vif-mediated degradation of APOBEC3G" XP_012237794.1 5 Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558 "PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_024227787.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_012246025.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003484955.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012247918.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012246852.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_003491799.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012244481.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_024224617.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_024227387.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003490236.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_003484462.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_024223249.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012236278.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_003492532.2 5 MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781 "Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)" XP_012246706.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012240622.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA" XP_024228070.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_012241415.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_003491370.1 8 Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-8953750;Reactome: R-HSA-5693554 "Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_024223150.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012244748.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_012248635.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_012249375.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_024220249.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024224477.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_024225532.1 13 Reactome: R-HSA-2214320;Reactome: R-HSA-1474244;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-216083;Reactome: R-HSA-419037;Reactome: R-HSA-3000157;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090 "Anchoring fibril formation";"Extracellular matrix organization";"Non-integrin membrane-ECM interactions";"Collagen degradation";"ECM proteoglycans";"Signaling by PDGF";"Collagen chain trimerization";"Integrin cell surface interactions";"NCAM1 interactions";"Laminin interactions";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures" XP_012237050.1 22 MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-6433;MetaCyc: PWY-7727;MetaCyc: PWY-5353;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6958;MetaCyc: PWY-7049;MetaCyc: PWY-7035 "Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis" XP_003485756.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_024220732.1 7 Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656 "Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry" XP_003488176.1 31 Reactome: R-HSA-163765;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-5973;MetaCyc: PWY-5366;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;MetaCyc: PWY-6799;MetaCyc: PWY-7664;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-5994;MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWY-8047;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-6282;MetaCyc: PWY-4381;MetaCyc: PWY-7746;MetaCyc: PWY-7388;MetaCyc: PWY-5367;MetaCyc: PWY-5147;MetaCyc: PWY-5971;MetaCyc: PWY-7723;MetaCyc: PWY-8049;MetaCyc: PWY-8012 "ChREBP activates metabolic gene expression";"";"Activation of gene expression by SREBF (SREBP)";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"Bryostatin biosynthesis";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Petroselinate biosynthesis";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bacterial bioluminescence";"Pederin biosynthesis";"Mupirocin biosynthesis" XP_003491894.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_012248290.1 14 Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4 "Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism" XP_012239949.1 11 Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-2979096 "Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_024226060.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_024221417.1 60 MetaCyc: PWY-7654;MetaCyc: PWY-6945;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;Reactome: R-HSA-1482798;MetaCyc: PWY-5136;KEGG: 00410+4.2.1.17;KEGG: 00650+4.2.1.17;MetaCyc: PWY-6863;KEGG: 00592+4.2.1.17;Reactome: R-HSA-77285;Reactome: R-HSA-77305;MetaCyc: PWY-7606;Reactome: R-HSA-77348;KEGG: 00903+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-6435;Reactome: R-HSA-77346;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;Reactome: R-HSA-77310;MetaCyc: PWY-5109;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-7656;MetaCyc: PWY-7401;KEGG: 00720+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-7094;MetaCyc: PWY-6946;MetaCyc: PWY-1361;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-6583;MetaCyc: PWY-7779;KEGG: 00310+4.2.1.17;KEGG: 00362+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00360+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;KEGG: 00281+4.2.1.17;KEGG: 00930+4.2.1.17;Reactome: R-HSA-77288;KEGG: 00640+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;KEGG: 00062+4.2.1.17+1.1.1.211 "(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Butanoate metabolism";"Glutaryl-coa degradation";"Tryptophan metabolism";"Fatty acid degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Acyl chain remodeling of CL";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Butanoate metabolism";"Pyruvate fermentation to hexanol (engineered)";"alpha-Linolenic acid metabolism";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Limonene and pinene degradation";"Geraniol degradation";"Aminobenzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"4-hydroxybenzoate biosynthesis III (plants)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fermentation to 2-methylbutanoate";"Caprolactam degradation";"Butanoate metabolism";"Androstenedione degradation";"Spodoptera littoralis pheromone biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Carbon fixation pathways in prokaryotes";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid salvage";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Benzoyl-coa degradation I (aerobic)";"Lysine degradation";"Valine, leucine and isoleucine degradation";"Fatty acid degradation";"Valine, leucine and isoleucine degradation";"2-methylpropene degradation";"Pyruvate fermentation to butanol I";"Methyl tert-butyl ether degradation";"Lysine degradation";"Benzoate degradation";"Toluene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Benzoate degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Phenylalanine metabolism";"Fatty acid elongation";"Tryptophan metabolism";"Geraniol degradation";"Caprolactam degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fatty acid elongation" XP_024228489.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_003492169.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_003485948.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003490036.1 11 MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7206;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9 "Tunicamycin biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Starch and sucrose metabolism";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis" XP_012248382.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_012236348.1 14 Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Dual Incision in GG-NER" XP_012244774.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_012244957.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_012246867.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695 "IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation" XP_024226268.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012246868.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_024226675.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_012236637.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" XP_012243871.1 19 Reactome: R-HSA-5663220;Reactome: R-HSA-3928662;Reactome: R-HSA-8964616;Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-182971;Reactome: R-HSA-194840;Reactome: R-HSA-5626467;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-4420097;Reactome: R-HSA-389359;Reactome: R-HSA-114604;Reactome: R-HSA-983231;Reactome: R-HSA-8950505;Reactome: R-HSA-525793;Reactome: R-HSA-5627123 "RHO GTPases Activate Formins";"EPHB-mediated forward signaling";"G beta:gamma signalling through CDC42";"DCC mediated attractive signaling";"RHO GTPases activate KTN1";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EGFR downregulation";"Rho GTPase cycle";"RHO GTPases activate IQGAPs";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"VEGFA-VEGFR2 Pathway";"CD28 dependent Vav1 pathway";"GPVI-mediated activation cascade";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Myogenesis";"RHO GTPases activate PAKs" XP_024220795.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_012244270.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012236107.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_012250174.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint" XP_024220697.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_024225361.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_003486971.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003491308.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_003493255.1 16 MetaCyc: PWY-7124;MetaCyc: PWY-7218;Reactome: R-HSA-70263;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6901;MetaCyc: PWY-1622;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-6886 "Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Rubisco shunt";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)" XP_024227688.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_012246023.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane" XP_024225490.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_024228440.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-380994 "FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_024226634.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012237586.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_012239750.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_012239169.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003489129.1 5 Reactome: R-HSA-111469;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-111463 "SMAC, XIAP-regulated apoptotic response";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs" XP_012240509.1 22 MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7053;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7727;MetaCyc: PWY-6433;MetaCyc: PWY-5353;MetaCyc: PWY-7728;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7049;MetaCyc: PWY-6958;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7592 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)" XP_012238507.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_012240244.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003487130.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_024224124.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012240740.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_012249956.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_012241924.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012240173.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012238306.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_003487432.1 5 KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Citrate cycle (TCA cycle)" XP_003489706.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_024220756.1 8 MetaCyc: PWY-7817;KEGG: 00564+3.1.3.27;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5269;KEGG: 05235+3.1.3.16;Reactome: R-HSA-1483148;MetaCyc: PWY-5668 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis II";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Synthesis of PG";"Cardiolipin biosynthesis I" XP_012240218.1 6 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;Reactome: R-HSA-3878781;MetaCyc: PWY-5067;MetaCyc: PWY-622 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis" XP_012241032.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-6799198 "Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis" XP_003484852.1 4 KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Selenocompound metabolism" XP_012237410.1 5 MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism" XP_012248153.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_003488208.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_024220736.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_024226815.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012250214.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_024221848.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858 "snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines" XP_012241345.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003494223.1 2 Reactome: R-HSA-2393930;MetaCyc: PWY-6502 "Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I" XP_012244391.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012246147.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_024220482.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012240452.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_003486163.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_024226082.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_024225867.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-111932 "Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB" XP_024223076.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012242082.1 17 MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7205;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7220 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_012242998.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003489708.1 6 Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-5099900 "Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4" XP_012239180.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024227041.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955 "Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_024227074.1 7 Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-1538133 "Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"G0 and Early G1" XP_003493749.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012239779.2 56 Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Ub-specific processing proteases";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling" XP_012245495.1 14 Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-113418 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex" XP_012237925.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_012241704.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_012240628.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_024226825.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003490258.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012241015.1 12 MetaCyc: PWY-6122;MetaCyc: PWY-6613;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.4.13;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.2;Reactome: R-HSA-196780;KEGG: 00230+6.3.3.1;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121 "5-aminoimidazole ribonucleotide biosynthesis II";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Aminoacyl-tRNA biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Biotin transport and metabolism";"Purine metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I" XP_012242922.1 8 Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652 "Ub-specific processing proteases";"Regulation of TP53 Degradation";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_003487607.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport" XP_003491657.1 12 Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167290 "Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation" XP_024228425.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_012240430.1 7 Reactome: R-HSA-5625886;Reactome: R-HSA-983231;Reactome: R-HSA-9029569;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Factors involved in megakaryocyte development and platelet production";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDMs demethylate histones";"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_024225723.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012239329.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_012245050.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012236096.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_012241056.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003487977.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_012238606.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_024224973.1 4 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism" XP_003491134.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_003489043.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012245499.1 2 KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105 "Fatty acid elongation";"Fatty acyl-CoA biosynthesis" XP_012242905.1 12 Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-381070;Reactome: R-HSA-189451;Reactome: R-HSA-381042;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-3371453;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;Reactome: R-HSA-381183 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"IRE1alpha activates chaperones";"Heme biosynthesis";"PERK regulates gene expression";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Regulation of HSF1-mediated heat shock response";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"ATF6 (ATF6-alpha) activates chaperone genes" XP_012244285.1 6 Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8863795 "Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2 signaling" XP_003490604.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012249492.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_012237094.2 3 Reactome: R-HSA-69273;Reactome: R-HSA-418594;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"G alpha (i) signalling events";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_012249916.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781 "Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression" XP_003484388.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012237770.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_003491297.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_003492140.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012242311.1 5 MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8 "Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation" XP_003489398.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_003491335.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012238775.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_012240284.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Respiratory electron transport";"Mitochondrial protein import" XP_012244425.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_012238234.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_024220623.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012250374.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_024222185.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_003484893.1 7 KEGG: 00983+2.7.4.14;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219 "Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_012245350.1 7 MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2 "Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism" XP_012246846.1 5 Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656237 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2" XP_003494587.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012248325.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003485182.1 19 KEGG: 00020+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;MetaCyc: PWY-5172;MetaCyc: PWY-7384;Reactome: R-HSA-163765;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5 "Citrate cycle (TCA cycle)";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Acetyl-coa biosynthesis III (from citrate)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"ChREBP activates metabolic gene expression";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes" XP_012241906.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012241449.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_012239167.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003494765.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_012246165.1 12 KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;MetaCyc: PWY-7817;MetaCyc: PWY-3801;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9 "Galactose metabolism";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Stachyose degradation";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_003494751.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-170822 "Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_003488186.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012244687.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_024225725.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_003487852.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_003486748.1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346 "ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis" XP_024224653.1 8 Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736 "RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors" XP_012245690.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012236736.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_024220794.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_003489208.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_012243234.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_012248812.1 10 MetaCyc: PWY-6362;MetaCyc: PWY-6369;MetaCyc: PWY-6361;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6372 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)" XP_012249960.1 13 MetaCyc: PWY-8086;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;KEGG: 00020+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-5392;MetaCyc: PWY-7384 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)" XP_003484589.1 2 Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_024220464.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_024223290.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_012238567.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012247383.1 40 Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-167162;Reactome: R-HSA-5617472;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-203927;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-168325 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"MicroRNA (miRNA) biogenesis";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis" XP_024226325.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" XP_003487149.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_024222657.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012236426.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_012238057.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_024223566.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012239509.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_012246631.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_003484836.1 8 Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2 "Ion channel transport";"Photosynthesis";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ATP biosynthesis";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Oxidative phosphorylation" XP_012244712.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_003493046.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012238538.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003494094.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_024222563.1 8 MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1 "Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Nitrogen metabolism" XP_003484634.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_003492223.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003489116.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012249672.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003485283.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_024223970.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_012244297.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012236231.1 5 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation" XP_012244565.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003494146.1 7 MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-7625 "3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)" XP_024227175.1 14 Reactome: R-HSA-611105;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-561 "Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_024220458.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_024225886.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736 "Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors" XP_012238695.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_012244798.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_024220496.1 8 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_003494345.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003485892.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_003491277.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_024220316.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_003486474.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_024226910.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_012241194.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_024224365.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_003484906.1 3 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway" XP_012247003.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012246018.2 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_024224957.1 8 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Recycling pathway of L1" XP_024222223.1 5 MetaCyc: PWY-6289;Reactome: R-HSA-199220;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012-1;MetaCyc: PWY-6012 "Petrobactin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Pantothenate and CoA biosynthesis";"Acyl carrier protein activation";"Acyl carrier protein metabolism" XP_024226848.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012249828.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_012247357.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012247417.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012249476.1 8 Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-167590 "Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation" XP_012238232.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_024226947.1 17 MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6679;MetaCyc: PWY-4381 "Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis";"Fatty acid biosynthesis";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Propanoate metabolism";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)" XP_012236962.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024228018.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_012244273.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_003486110.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012236414.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_024224755.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_012238678.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_003491853.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_024223944.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_024225702.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_012245013.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_024224280.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_024225785.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012241908.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003486466.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_003484928.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_024226083.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_003488993.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003489504.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_024226298.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_024227343.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012249268.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_012241757.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_024228398.1 13 Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-4086398;Reactome: R-HSA-983695;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509 "VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Ca2+ pathway";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling" XP_012248470.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_024220777.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression" XP_012243504.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003491185.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_024223352.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_024226737.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_003489872.1 17 Reactome: R-HSA-674695;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167242;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-113418;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167246;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"Th1 and Th2 cell differentiation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"T cell receptor signaling pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex" XP_012240777.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_024225307.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_024222894.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012236790.1 14 Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397 "HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_003492579.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_024221072.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_003487789.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_012244530.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_024223903.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_003491236.1 9 Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-3642279;Reactome: R-HSA-3656535;Reactome: R-HSA-2173791;Reactome: R-HSA-3645790;Reactome: R-HSA-5689603;Reactome: R-HSA-3304356 "TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 Kinase Domain Mutants in Cancer";"UCH proteinases";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_012241429.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_003486951.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_024222586.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-164843 "Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation" XP_003485310.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012246943.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003485305.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012239637.1 24 Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-437239 "MHC class II antigen presentation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Separation of Sister Chromatids";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"Aggrephagy";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1" XP_024227764.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_024228325.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003487678.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_003488125.1 22 Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348 "Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"RAF activation";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex" XP_012249452.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_012236829.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_024220410.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012239147.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_024227844.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_012242700.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003488371.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Eukaryotic Translation Termination" XP_003491176.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012238864.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7 "Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis" XP_024221810.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_024227187.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012237563.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_003488847.1 4 KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_003493427.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_024220701.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003485017.1 24 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-420092;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-9009391;Reactome: R-HSA-400042 "G alpha (q) signalling events";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G-protein activation";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion" XP_012238064.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_024228084.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_012238747.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_024224645.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_024223711.1 13 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-416572;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-3928663;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"Sema4D induced cell migration and growth-cone collapse";"Human papillomavirus infection";"RHO GTPases Activate ROCKs";"EPHA-mediated growth cone collapse";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway" XP_012242380.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins" XP_003485762.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003492582.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003491282.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_003491261.1 33 MetaCyc: PWY-7396;KEGG: 00010+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-5082;MetaCyc: PWY-6587;MetaCyc: PWY-5751;MetaCyc: PWY-6333;MetaCyc: PWY-5076;MetaCyc: PWY-6802;MetaCyc: PWY-5480;MetaCyc: PWY-5057;MetaCyc: PWY-6871;MetaCyc: PWY-5078;KEGG: 00830+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-5486;MetaCyc: PWY-7111;KEGG: 00680+1.1.1.284;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00625+1.1.1.1;KEGG: 00071+1.1.1.1;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-1801;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-7798;KEGG: 00982+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-3162 "Butanol and isobutanol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Serotonin degradation";"L-methionine degradation III";"Pyruvate fermentation to ethanol III";"Phenylethanol biosynthesis";"Acetaldehyde biosynthesis I";"L-leucine degradation III";"Salidroside biosynthesis";"Pyruvate fermentation to ethanol I";"L-valine degradation II";"3-methylbutanol biosynthesis (engineered)";"L-isoleucine degradation II";"Retinol metabolism";"Ethanol oxidation";"Pyruvate fermentation to ethanol II";"Pyruvate fermentation to isobutanol (engineered)";"Methane metabolism";"alpha-Linolenic acid metabolism";"(S)-propane-1,2-diol degradation";"Chloroalkane and chloroalkene degradation";"Fatty acid degradation";"Tyrosine metabolism";"L-phenylalanine degradation III";"Formaldehyde oxidation II (glutathione-dependent)";"Metabolism of xenobiotics by cytochrome P450";"Chitin degradation to ethanol";"Protein S-nitrosylation and denitrosylation";"Drug metabolism - cytochrome P450";"Naphthalene degradation";"Noradrenaline and adrenaline degradation";"L-tryptophan degradation V (side chain pathway)" XP_024223283.1 6 MetaCyc: PWY-6368;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;Reactome: R-HSA-1660517;KEGG: 04070+3.1.3.64;KEGG: 00562+3.1.3.64 "3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism" XP_012247167.1 17 Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744 "Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Glyoxylate assimilation" XP_012244951.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012244176.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012248154.1 7 KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;MetaCyc: PWY-7625 "Inositol phosphate metabolism";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)" XP_024227510.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_024223918.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"